|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
1009-1244 |
6.86e-51 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
:
Pssm-ID: 397130 Cd Length: 203 Bit Score: 178.71 E-value: 6.86e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 1009 QRKVKGSLNKMTLEKFDKISDQILEIAMQsrkenDGRTLKQVIQLTFEKATDEPNFSNMYARFARKMMDSIDdsirdegv 1088
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMS-----DPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNLRNP-------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 1089 ldknnqpvrggLLFRKYLLSRCQEDFERGwkanlpsgkageAEIMSDEYyvaaAIKRRGLGLVRFIGELFKLSMLSEKIM 1168
Cdd:pfam02854 68 -----------TDFGIHLLNRLQEEFEKR------------FELEENEQ----GNRRRRLGLVRFLGELYKFGLLTEKIL 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 1169 HECIKRLLGNVTDPE----EEEIESLCRLLMTVGVNIDaTEKGHAAMDVYVLRMETITKI---PNLPSRIKFMLMDVMDS 1241
Cdd:pfam02854 121 FECLKELLSSLTKEDlkrdLFNLECLLTLLTTIGKLLE-NEKLPKLMDQFLDEIQKYVLSkddPKLSSRLRFMLQDLIEL 199
|
...
gi 19115514 1242 RKN 1244
Cdd:pfam02854 200 RKN 202
|
|
| eIF_4G1 |
pfam12152 |
Eukaryotic translation initiation factor 4G1; This domain is found in eukaryotes, and is about ... |
793-846 |
9.89e-11 |
|
Eukaryotic translation initiation factor 4G1; This domain is found in eukaryotes, and is about 80 amino acids in length. It is found in association with pfam02854. This domain is part of the protein eIF_4G. It binds to eIF_4E by wrapping around its N terminal to form the eIF_4F complex. This complex binds various eIF_4E-BPs (binding proteins) to regulate initiation of translation.
:
Pssm-ID: 432365 [Multi-domain] Cd Length: 60 Bit Score: 58.38 E-value: 9.89e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 19115514 793 LESLLNSQFITDFSALVYPSTIKPPSTEEALKAGKYEYDVPFLLQFQSVYTDKP 846
Cdd:pfam12152 6 LESLKSARPIEDIYSFKYPEGIESPDPALNKEAVKYRYDPDFLLQFKDVVKEKP 59
|
|
| Herpes_BLLF1 super family |
cl37540 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
2-290 |
1.97e-06 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
The actual alignment was detected with superfamily member pfam05109:
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 52.61 E-value: 1.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 2 SSKPPSNTPKFSYARALASSQSNKS-NSTKASENNTATAekqavKPSGVE-PTNTSRANAQKKTESTGKITSEADTEKyN 79
Cdd:pfam05109 409 ATNATTTTHKVIFSKAPESTTTSPTlNTTGFAAPNTTTG-----LPSSTHvPTNLTAPASTGPTVSTADVTSPTPAGT-T 482
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 80 SSKSPVNKEGSVEKKSSE-KSSTNNKPWRGDNTSKPSANSSAERTSSQHQKPeTSSQIGKdnAAPVENVNEKSTSQETAP 158
Cdd:pfam05109 483 SGASPVTPSPSPRDNGTEsKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNA-TSPTLGK--TSPTSAVTTPTPNATSPT 559
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 159 PVSTVPiqfgsiTRNAAIPSKPKVSGNMQNKSGVSSYSSKSQSVNSSVTSNPPHT-----EEPVAAKP--EASSTATKGP 231
Cdd:pfam05109 560 PAVTTP------TPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTlggtsSTPVVTSPpkNATSAVTTGQ 633
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 232 RPTTSASNTNTS--PANGAPTNKPSTDINTTD--------------------PATQTTQVSASNSPA-----LSGSSTPS 284
Cdd:pfam05109 634 HNITSSSTSSMSlrPSSISETLSPSTSDNSTShmplltsahptggenitqvtPASTSTHHVSTSSPAprpgtTSQASGPG 713
|
....*.
gi 19115514 285 NTSSRS 290
Cdd:pfam05109 714 NSSTST 719
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
470-574 |
1.75e-03 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
:
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 42.14 E-value: 1.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 470 QQKKSSALKIVNPVThTEVVVPQKNASSPNPsetNSRAETPTAAPPQISEEEASQRKDAIKLAI------QQRIQEKAEA 543
Cdd:TIGR02794 25 HSVKPEPGGGAEIIQ-AVLVDPGAVAQQANR---IQQQKKPAAKKEQERQKKLEQQAEEAEKQRaaeqarQKELEQRAAA 100
|
90 100 110
....*....|....*....|....*....|.
gi 19115514 544 EAKRKAEEKARLEAEENaKREAEEQAKREAE 574
Cdd:TIGR02794 101 EKAAKQAEQAAKQAEEK-QKQAEEAKAKQAA 130
|
|
| PTZ00121 super family |
cl31754 |
MAEBL; Provisional |
501-756 |
2.13e-03 |
|
MAEBL; Provisional
The actual alignment was detected with superfamily member PTZ00121:
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 42.82 E-value: 2.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 501 SETNSRAETPTAAPPQISEEEASQRKDAIKLAIQQRIQEKAEAEAKRKAEEKARLEAEENAKREAEEQAKREAEEKAKRE 580
Cdd:PTZ00121 1506 AEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEE 1585
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 581 AEEKAKREAEEKAKREAEENAKREAEEKAKREAEEKAKREAEEKAKREAEEKAKREAEEKAKREAEEKAKREAEEKAKRE 660
Cdd:PTZ00121 1586 AKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE 1665
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 661 AEENAKREAEEKAKREAEENAKREAEEKVKRETEEnaKRKAEEEGKREADknpEIKSSAPLASSEaNVDTSKQTNATEPE 740
Cdd:PTZ00121 1666 EAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEE--AKKAEELKKKEAE---EKKKAEELKKAE-EENKIKAEEAKKEA 1739
|
250
....*....|....*.
gi 19115514 741 VVDKTKVEKLKASEGK 756
Cdd:PTZ00121 1740 EEDKKKAEEAKKDEEE 1755
|
|
| PRK10263 super family |
cl35903 |
DNA translocase FtsK; Provisional |
215-567 |
5.92e-03 |
|
DNA translocase FtsK; Provisional
The actual alignment was detected with superfamily member PRK10263:
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 41.22 E-value: 5.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 215 EPVAAKPEASSTATKGPRPTTSASNTNTSPANGAPTNKPSTDINTTdPATQTTQVSASNSPAlsgSSTPSNTSSRSNRQN 294
Cdd:PRK10263 318 EPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQPV-PGPQTGEPVIAPAPE---GYPQQSQYAQPAVQY 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 295 HGNFSEkrhydrygnshPSYNKYSHYQHGFNYNNSGNNRNEsgHPRFRNSRRNYNNQGAYPTYMSNGRSANQSPRNNPQN 374
Cdd:PRK10263 394 NEPLQQ-----------PVQPQQPYYAPAAEQPAQQPYYAP--APEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQS 460
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 375 VNNGSTPIQIPVSLQTPYGQvygqPQYIVDPNMVQYGPILQ---PGYVPQYYpvyhqtpYTQNFPNMSRSGSQVSD--QV 449
Cdd:PRK10263 461 TYQTEQTYQQPAAQEPLYQQ----PQPVEQQPVVEPEPVVEetkPARPPLYY-------FEEVEEKRAREREQLAAwyQP 529
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 450 VESPNSSTLsprngfapIVKQQKKSSALKIVNPVTHTEVVVPQknASSPNPSETNSRAETPTAAP-----------PQIS 518
Cdd:PRK10263 530 IPEPVKEPE--------PIKSSLKAPSVAAVPPVEAAAAVSPL--ASGVKKATLATGAAATVAAPvfslansggprPQVK 599
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19115514 519 EEEASQ-----------RKD----AIKLAIQQRIQEKAEAEAKRKAEEKARLEAEENAKREAEE 567
Cdd:PRK10263 600 EGIGPQlprpkrirvptRRElasyGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDE 663
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
1009-1244 |
6.86e-51 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
Pssm-ID: 397130 Cd Length: 203 Bit Score: 178.71 E-value: 6.86e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 1009 QRKVKGSLNKMTLEKFDKISDQILEIAMQsrkenDGRTLKQVIQLTFEKATDEPNFSNMYARFARKMMDSIDdsirdegv 1088
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMS-----DPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNLRNP-------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 1089 ldknnqpvrggLLFRKYLLSRCQEDFERGwkanlpsgkageAEIMSDEYyvaaAIKRRGLGLVRFIGELFKLSMLSEKIM 1168
Cdd:pfam02854 68 -----------TDFGIHLLNRLQEEFEKR------------FELEENEQ----GNRRRRLGLVRFLGELYKFGLLTEKIL 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 1169 HECIKRLLGNVTDPE----EEEIESLCRLLMTVGVNIDaTEKGHAAMDVYVLRMETITKI---PNLPSRIKFMLMDVMDS 1241
Cdd:pfam02854 121 FECLKELLSSLTKEDlkrdLFNLECLLTLLTTIGKLLE-NEKLPKLMDQFLDEIQKYVLSkddPKLSSRLRFMLQDLIEL 199
|
...
gi 19115514 1242 RKN 1244
Cdd:pfam02854 200 RKN 202
|
|
| MIF4G |
smart00543 |
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The ... |
1009-1244 |
1.53e-43 |
|
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA. Ponting (TiBS) "Novel eIF4G domain homologues (in press)
Pssm-ID: 214713 Cd Length: 200 Bit Score: 157.52 E-value: 1.53e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 1009 QRKVKGSLNKMTLEKFDKISDQILEIAMQsrkenDGRTLKQVIQLTFEKATDEPNFSNMYARFARKMMDSIDDsirdegv 1088
Cdd:smart00543 1 EKKVKGLINKLSPSNFESIIKELLKLNNS-----DKNLRKYILELIFEKAVEEPNFIPAYARLCALLNAKNPD------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 1089 ldknnqpvrggllFRKYLLSRCQEDFERGwkanlpsgkageaeimsdEYYVAAAIKRRGLGLVRFIGELFKLSMLSEKIM 1168
Cdd:smart00543 69 -------------FGSLLLERLQEEFEKG------------------LESEEESDKQRRLGLVRFLGELYNFQVLTSKII 117
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 1169 HECIKRLLGNVTDPE----EEEIESLCRLLMTVGVNIDAtEKGHAAMDVYVLRMETITKIP---NLPSRIKFMLMDVMDS 1241
Cdd:smart00543 118 LELLKELLNDLTKLDpprsDFSVECLLSLLPTCGKDLER-EKSPKLLDEILERLQDYLLKKdktELSSRLRFMLELLIEL 196
|
...
gi 19115514 1242 RKN 1244
Cdd:smart00543 197 RKN 199
|
|
| eIF_4G1 |
pfam12152 |
Eukaryotic translation initiation factor 4G1; This domain is found in eukaryotes, and is about ... |
793-846 |
9.89e-11 |
|
Eukaryotic translation initiation factor 4G1; This domain is found in eukaryotes, and is about 80 amino acids in length. It is found in association with pfam02854. This domain is part of the protein eIF_4G. It binds to eIF_4E by wrapping around its N terminal to form the eIF_4F complex. This complex binds various eIF_4E-BPs (binding proteins) to regulate initiation of translation.
Pssm-ID: 432365 [Multi-domain] Cd Length: 60 Bit Score: 58.38 E-value: 9.89e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 19115514 793 LESLLNSQFITDFSALVYPSTIKPPSTEEALKAGKYEYDVPFLLQFQSVYTDKP 846
Cdd:pfam12152 6 LESLKSARPIEDIYSFKYPEGIESPDPALNKEAVKYRYDPDFLLQFKDVVKEKP 59
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
2-290 |
1.97e-06 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 52.61 E-value: 1.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 2 SSKPPSNTPKFSYARALASSQSNKS-NSTKASENNTATAekqavKPSGVE-PTNTSRANAQKKTESTGKITSEADTEKyN 79
Cdd:pfam05109 409 ATNATTTTHKVIFSKAPESTTTSPTlNTTGFAAPNTTTG-----LPSSTHvPTNLTAPASTGPTVSTADVTSPTPAGT-T 482
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 80 SSKSPVNKEGSVEKKSSE-KSSTNNKPWRGDNTSKPSANSSAERTSSQHQKPeTSSQIGKdnAAPVENVNEKSTSQETAP 158
Cdd:pfam05109 483 SGASPVTPSPSPRDNGTEsKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNA-TSPTLGK--TSPTSAVTTPTPNATSPT 559
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 159 PVSTVPiqfgsiTRNAAIPSKPKVSGNMQNKSGVSSYSSKSQSVNSSVTSNPPHT-----EEPVAAKP--EASSTATKGP 231
Cdd:pfam05109 560 PAVTTP------TPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTlggtsSTPVVTSPpkNATSAVTTGQ 633
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 232 RPTTSASNTNTS--PANGAPTNKPSTDINTTD--------------------PATQTTQVSASNSPA-----LSGSSTPS 284
Cdd:pfam05109 634 HNITSSSTSSMSlrPSSISETLSPSTSDNSTShmplltsahptggenitqvtPASTSTHHVSTSSPAprpgtTSQASGPG 713
|
....*.
gi 19115514 285 NTSSRS 290
Cdd:pfam05109 714 NSSTST 719
|
|
| PRK13914 |
PRK13914 |
invasion associated endopeptidase; |
18-140 |
8.63e-06 |
|
invasion associated endopeptidase;
Pssm-ID: 237555 [Multi-domain] Cd Length: 481 Bit Score: 50.19 E-value: 8.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 18 LASSQSNKSNSTKASENNTATAEKQAVKPSGVEPTNTSRANAQKKTESTGK-ITSEADTEKYNSSKSPVNKEGSVEKKSS 96
Cdd:PRK13914 241 LAIKQTANTATPKAEVKTEAPAAEKQAAPVVKENTNTNTATTEKKETTTQQqTAPKAPTEAAKPAPAPSTNTNANKTNTN 320
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 19115514 97 EKSSTNNkpwrgDNTSKPSANSSAERTSSQHQKPETSSQIGKDN 140
Cdd:PRK13914 321 TNTNTNN-----TNTSTPSKNTNTNTNSNTNTNSNTNANQGSSN 359
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
470-574 |
1.75e-03 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 42.14 E-value: 1.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 470 QQKKSSALKIVNPVThTEVVVPQKNASSPNPsetNSRAETPTAAPPQISEEEASQRKDAIKLAI------QQRIQEKAEA 543
Cdd:TIGR02794 25 HSVKPEPGGGAEIIQ-AVLVDPGAVAQQANR---IQQQKKPAAKKEQERQKKLEQQAEEAEKQRaaeqarQKELEQRAAA 100
|
90 100 110
....*....|....*....|....*....|.
gi 19115514 544 EAKRKAEEKARLEAEENaKREAEEQAKREAE 574
Cdd:TIGR02794 101 EKAAKQAEQAAKQAEEK-QKQAEEAKAKQAA 130
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
501-756 |
2.13e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 42.82 E-value: 2.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 501 SETNSRAETPTAAPPQISEEEASQRKDAIKLAIQQRIQEKAEAEAKRKAEEKARLEAEENAKREAEEQAKREAEEKAKRE 580
Cdd:PTZ00121 1506 AEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEE 1585
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 581 AEEKAKREAEEKAKREAEENAKREAEEKAKREAEEKAKREAEEKAKREAEEKAKREAEEKAKREAEEKAKREAEEKAKRE 660
Cdd:PTZ00121 1586 AKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE 1665
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 661 AEENAKREAEEKAKREAEENAKREAEEKVKRETEEnaKRKAEEEGKREADknpEIKSSAPLASSEaNVDTSKQTNATEPE 740
Cdd:PTZ00121 1666 EAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEE--AKKAEELKKKEAE---EKKKAEELKKAE-EENKIKAEEAKKEA 1739
|
250
....*....|....*.
gi 19115514 741 VVDKTKVEKLKASEGK 756
Cdd:PTZ00121 1740 EEDKKKAEEAKKDEEE 1755
|
|
| TolA |
COG3064 |
Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis]; |
516-568 |
3.48e-03 |
|
Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442298 [Multi-domain] Cd Length: 485 Bit Score: 41.56 E-value: 3.48e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 19115514 516 QISEEEASQRKDAIKLAIQQRIQEKAE----AEAKRKAEEKARLEAEENAKREAEEQ 568
Cdd:COG3064 92 KAAAEKAKAAKEAEAAAAAEKAAAAAEkekaEEAKRKAEEEAKRKAEEERKAAEAEA 148
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
215-567 |
5.92e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 41.22 E-value: 5.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 215 EPVAAKPEASSTATKGPRPTTSASNTNTSPANGAPTNKPSTDINTTdPATQTTQVSASNSPAlsgSSTPSNTSSRSNRQN 294
Cdd:PRK10263 318 EPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQPV-PGPQTGEPVIAPAPE---GYPQQSQYAQPAVQY 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 295 HGNFSEkrhydrygnshPSYNKYSHYQHGFNYNNSGNNRNEsgHPRFRNSRRNYNNQGAYPTYMSNGRSANQSPRNNPQN 374
Cdd:PRK10263 394 NEPLQQ-----------PVQPQQPYYAPAAEQPAQQPYYAP--APEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQS 460
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 375 VNNGSTPIQIPVSLQTPYGQvygqPQYIVDPNMVQYGPILQ---PGYVPQYYpvyhqtpYTQNFPNMSRSGSQVSD--QV 449
Cdd:PRK10263 461 TYQTEQTYQQPAAQEPLYQQ----PQPVEQQPVVEPEPVVEetkPARPPLYY-------FEEVEEKRAREREQLAAwyQP 529
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 450 VESPNSSTLsprngfapIVKQQKKSSALKIVNPVTHTEVVVPQknASSPNPSETNSRAETPTAAP-----------PQIS 518
Cdd:PRK10263 530 IPEPVKEPE--------PIKSSLKAPSVAAVPPVEAAAAVSPL--ASGVKKATLATGAAATVAAPvfslansggprPQVK 599
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19115514 519 EEEASQ-----------RKD----AIKLAIQQRIQEKAEAEAKRKAEEKARLEAEENAKREAEE 567
Cdd:PRK10263 600 EGIGPQlprpkrirvptRRElasyGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDE 663
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
1009-1244 |
6.86e-51 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
Pssm-ID: 397130 Cd Length: 203 Bit Score: 178.71 E-value: 6.86e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 1009 QRKVKGSLNKMTLEKFDKISDQILEIAMQsrkenDGRTLKQVIQLTFEKATDEPNFSNMYARFARKMMDSIDdsirdegv 1088
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMS-----DPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNLRNP-------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 1089 ldknnqpvrggLLFRKYLLSRCQEDFERGwkanlpsgkageAEIMSDEYyvaaAIKRRGLGLVRFIGELFKLSMLSEKIM 1168
Cdd:pfam02854 68 -----------TDFGIHLLNRLQEEFEKR------------FELEENEQ----GNRRRRLGLVRFLGELYKFGLLTEKIL 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 1169 HECIKRLLGNVTDPE----EEEIESLCRLLMTVGVNIDaTEKGHAAMDVYVLRMETITKI---PNLPSRIKFMLMDVMDS 1241
Cdd:pfam02854 121 FECLKELLSSLTKEDlkrdLFNLECLLTLLTTIGKLLE-NEKLPKLMDQFLDEIQKYVLSkddPKLSSRLRFMLQDLIEL 199
|
...
gi 19115514 1242 RKN 1244
Cdd:pfam02854 200 RKN 202
|
|
| MIF4G |
smart00543 |
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The ... |
1009-1244 |
1.53e-43 |
|
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA. Ponting (TiBS) "Novel eIF4G domain homologues (in press)
Pssm-ID: 214713 Cd Length: 200 Bit Score: 157.52 E-value: 1.53e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 1009 QRKVKGSLNKMTLEKFDKISDQILEIAMQsrkenDGRTLKQVIQLTFEKATDEPNFSNMYARFARKMMDSIDDsirdegv 1088
Cdd:smart00543 1 EKKVKGLINKLSPSNFESIIKELLKLNNS-----DKNLRKYILELIFEKAVEEPNFIPAYARLCALLNAKNPD------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 1089 ldknnqpvrggllFRKYLLSRCQEDFERGwkanlpsgkageaeimsdEYYVAAAIKRRGLGLVRFIGELFKLSMLSEKIM 1168
Cdd:smart00543 69 -------------FGSLLLERLQEEFEKG------------------LESEEESDKQRRLGLVRFLGELYNFQVLTSKII 117
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 1169 HECIKRLLGNVTDPE----EEEIESLCRLLMTVGVNIDAtEKGHAAMDVYVLRMETITKIP---NLPSRIKFMLMDVMDS 1241
Cdd:smart00543 118 LELLKELLNDLTKLDpprsDFSVECLLSLLPTCGKDLER-EKSPKLLDEILERLQDYLLKKdktELSSRLRFMLELLIEL 196
|
...
gi 19115514 1242 RKN 1244
Cdd:smart00543 197 RKN 199
|
|
| eIF_4G1 |
pfam12152 |
Eukaryotic translation initiation factor 4G1; This domain is found in eukaryotes, and is about ... |
793-846 |
9.89e-11 |
|
Eukaryotic translation initiation factor 4G1; This domain is found in eukaryotes, and is about 80 amino acids in length. It is found in association with pfam02854. This domain is part of the protein eIF_4G. It binds to eIF_4E by wrapping around its N terminal to form the eIF_4F complex. This complex binds various eIF_4E-BPs (binding proteins) to regulate initiation of translation.
Pssm-ID: 432365 [Multi-domain] Cd Length: 60 Bit Score: 58.38 E-value: 9.89e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 19115514 793 LESLLNSQFITDFSALVYPSTIKPPSTEEALKAGKYEYDVPFLLQFQSVYTDKP 846
Cdd:pfam12152 6 LESLKSARPIEDIYSFKYPEGIESPDPALNKEAVKYRYDPDFLLQFKDVVKEKP 59
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
2-290 |
1.97e-06 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 52.61 E-value: 1.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 2 SSKPPSNTPKFSYARALASSQSNKS-NSTKASENNTATAekqavKPSGVE-PTNTSRANAQKKTESTGKITSEADTEKyN 79
Cdd:pfam05109 409 ATNATTTTHKVIFSKAPESTTTSPTlNTTGFAAPNTTTG-----LPSSTHvPTNLTAPASTGPTVSTADVTSPTPAGT-T 482
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 80 SSKSPVNKEGSVEKKSSE-KSSTNNKPWRGDNTSKPSANSSAERTSSQHQKPeTSSQIGKdnAAPVENVNEKSTSQETAP 158
Cdd:pfam05109 483 SGASPVTPSPSPRDNGTEsKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNA-TSPTLGK--TSPTSAVTTPTPNATSPT 559
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 159 PVSTVPiqfgsiTRNAAIPSKPKVSGNMQNKSGVSSYSSKSQSVNSSVTSNPPHT-----EEPVAAKP--EASSTATKGP 231
Cdd:pfam05109 560 PAVTTP------TPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTlggtsSTPVVTSPpkNATSAVTTGQ 633
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 232 RPTTSASNTNTS--PANGAPTNKPSTDINTTD--------------------PATQTTQVSASNSPA-----LSGSSTPS 284
Cdd:pfam05109 634 HNITSSSTSSMSlrPSSISETLSPSTSDNSTShmplltsahptggenitqvtPASTSTHHVSTSSPAprpgtTSQASGPG 713
|
....*.
gi 19115514 285 NTSSRS 290
Cdd:pfam05109 714 NSSTST 719
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
6-568 |
7.13e-06 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 50.92 E-value: 7.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 6 PSNTPKFSYARALASSQSNKSNSTKASENNTATAEKQAVKPSGVEPT------------NTSRANAQK-KTESTGKITSE 72
Cdd:pfam03154 34 PTNEDLRSSGRNSPSAASTSSNDSKAESMKKSSKKIKEEAPSPLKSAkrqrekgasdteEPERATAKKsKTQEISRPNSP 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 73 ADTEKYNSSKSPVNKEGSVEKK---SSEKSSTNNKPWRGDNTSkpSANSSAERTSSQHQKPETSSQIGKDNAAPVENVNE 149
Cdd:pfam03154 114 SEGEGESSDGRSVNDEGSSDPKdidQDNRSTSPSIPSPQDNES--DSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGT 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 150 KSTSQETAPP-VSTVPIQFGSITR---NAAIPSKPKVSGNMQNKSGVSSYSSKSQSVNSSVTSNPPHTEEPVAAKPEASS 225
Cdd:pfam03154 192 TQAATAGPTPsAPSVPPQGSPATSqppNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSL 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 226 TATKGPRPTTSASNTNTSPANGAPtnkpstdinttDPATQTTQVSASNSPALSGSSTPSNTSSRSNRQNHGNFSEKRHYD 305
Cdd:pfam03154 272 HGQMPPMPHSLQTGPSHMQHPVPP-----------QPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPP 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 306 RYGNSHPSYNKYSHYQHGFNYNNSGNNRNES-GHPRFRNSRRNYNNQGAYP--------TYMSNGRSANQSP---RNNPQ 373
Cdd:pfam03154 341 REQPLPPAPLSMPHIKPPPTTPIPQLPNPQShKHPPHLSGPSPFQMNSNLPpppalkplSSLSTHHPPSAHPpplQLMPQ 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 374 NVNNGSTPIQIPVSLQTPYGQVYG--QPQYIVDPNMVQYGPILQPGYVPQYYPVYhqTPYTQNFPNMSRSGSQVSDQVVE 451
Cdd:pfam03154 421 SQQLPPPPAQPPVLTQSQSLPPPAasHPPTSGLHQVPSQSPFPQHPFVPGGPPPI--TPPSGPPTSTSSAMPGIQPPSSA 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 452 SPNSSTLSPRNGFAPIVKQQKKSSALkivNPVTHTEVVVPQKNASSPNPSETNSRAETPTAAPPQISEEE---ASQRKD- 527
Cdd:pfam03154 499 SVSSSGPVPAAVSCPLPPVQIKEEAL---DEAEEPESPPPPPRSPSPEPTVVNTPSHASQSARFYKHLDRgynSCARTDl 575
|
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 19115514 528 ------AIKLAiqqRIQEKAEAEAKRKAEEKARLEAEENAKREAEEQ 568
Cdd:pfam03154 576 yfmplaGSKLA---KKREEALEKAKREAEQKAREEKEREKEKEKERE 619
|
|
| PRK13914 |
PRK13914 |
invasion associated endopeptidase; |
18-140 |
8.63e-06 |
|
invasion associated endopeptidase;
Pssm-ID: 237555 [Multi-domain] Cd Length: 481 Bit Score: 50.19 E-value: 8.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 18 LASSQSNKSNSTKASENNTATAEKQAVKPSGVEPTNTSRANAQKKTESTGK-ITSEADTEKYNSSKSPVNKEGSVEKKSS 96
Cdd:PRK13914 241 LAIKQTANTATPKAEVKTEAPAAEKQAAPVVKENTNTNTATTEKKETTTQQqTAPKAPTEAAKPAPAPSTNTNANKTNTN 320
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 19115514 97 EKSSTNNkpwrgDNTSKPSANSSAERTSSQHQKPETSSQIGKDN 140
Cdd:PRK13914 321 TNTNTNN-----TNTSTPSKNTNTNTNSNTNTNSNTNANQGSSN 359
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
470-574 |
1.75e-03 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 42.14 E-value: 1.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 470 QQKKSSALKIVNPVThTEVVVPQKNASSPNPsetNSRAETPTAAPPQISEEEASQRKDAIKLAI------QQRIQEKAEA 543
Cdd:TIGR02794 25 HSVKPEPGGGAEIIQ-AVLVDPGAVAQQANR---IQQQKKPAAKKEQERQKKLEQQAEEAEKQRaaeqarQKELEQRAAA 100
|
90 100 110
....*....|....*....|....*....|.
gi 19115514 544 EAKRKAEEKARLEAEENaKREAEEQAKREAE 574
Cdd:TIGR02794 101 EKAAKQAEQAAKQAEEK-QKQAEEAKAKQAA 130
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
501-756 |
2.13e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 42.82 E-value: 2.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 501 SETNSRAETPTAAPPQISEEEASQRKDAIKLAIQQRIQEKAEAEAKRKAEEKARLEAEENAKREAEEQAKREAEEKAKRE 580
Cdd:PTZ00121 1506 AEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEE 1585
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 581 AEEKAKREAEEKAKREAEENAKREAEEKAKREAEEKAKREAEEKAKREAEEKAKREAEEKAKREAEEKAKREAEEKAKRE 660
Cdd:PTZ00121 1586 AKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE 1665
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 661 AEENAKREAEEKAKREAEENAKREAEEKVKRETEEnaKRKAEEEGKREADknpEIKSSAPLASSEaNVDTSKQTNATEPE 740
Cdd:PTZ00121 1666 EAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEE--AKKAEELKKKEAE---EKKKAEELKKAE-EENKIKAEEAKKEA 1739
|
250
....*....|....*.
gi 19115514 741 VVDKTKVEKLKASEGK 756
Cdd:PTZ00121 1740 EEDKKKAEEAKKDEEE 1755
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
6-283 |
2.25e-03 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 42.25 E-value: 2.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 6 PSNTPKFSYARALASSQSNKSNSTKASENNTATAEKQAVKPSGVEPTNTSRANAQKKTESTGKITSEADTEKYNSSKSPV 85
Cdd:pfam17823 69 PVTLTKGTSAAHLNSTEVTAEHTPHGTDLSEPATREGAADGAASRALAAAASSSPSSAAQSLPAAIAALPSEAFSAPRAA 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 86 NKEGSVEKKSSEKSSTNNKPWRGDNTSKPSANSS--AERTSSQHQKPETSSQIGKDNAAPVENVNEKSTSQETaPPVSTV 163
Cdd:pfam17823 149 ACRANASAAPRAAIAAASAPHAASPAPRTAASSTtaASSTTAASSAPTTAASSAPATLTPARGISTAATATGH-PAAGTA 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 164 PIQFGSITRNAAIPSKPKVSGNMQNKSGVSSYSSKSQSVNSSVTSNPPHTEEPVAAKPEASSTATKGP------------ 231
Cdd:pfam17823 228 LAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAKHMPSDTMARNPaapmgaqaqgpi 307
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 19115514 232 --------------RPTTSASNTNTSPANGAPTNKPSTDINTTDPAtQTTQVSASNSPALSGSSTP 283
Cdd:pfam17823 308 iqvstdqpvhntagEPTPSPSNTTLEPNTPKSVASTNLAVVTTTKA-QAKEPSASPVPVLHTSMIP 372
|
|
| PRK13914 |
PRK13914 |
invasion associated endopeptidase; |
51-281 |
3.22e-03 |
|
invasion associated endopeptidase;
Pssm-ID: 237555 [Multi-domain] Cd Length: 481 Bit Score: 41.71 E-value: 3.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 51 PTNTSRANAQKKTESTGKITSEADTEKYNSSKSPVNKEGSVEKKSS---EKSSTNNKPWRGDNTSKPSAN--SSAERTSS 125
Cdd:PRK13914 147 PVAPTQEVKKETTTQQAAPAAETKTEVKQTTQATTPAPKVAETKETpvvDQNATTHAVKSGDTIWALSVKygVSVQDIMS 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 126 QHQKPETSSQIGKDNAApvenvnekSTSQETAPPVSTVPIQFGSITRNAAipskPKVSGNmQNKSGVSSYSSKSQSVNSS 205
Cdd:PRK13914 227 WNNLSSSSIYVGQKLAI--------KQTANTATPKAEVKTEAPAAEKQAA----PVVKEN-TNTNTATTEKKETTTQQQT 293
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 19115514 206 VTSNPPHTEEPVAAkPEASSTATKGPRPTTSASNTNTSPANGAPTNKPSTDINTTDPATQTTQVSASNSPALSGSS 281
Cdd:PRK13914 294 APKAPTEAAKPAPA-PSTNTNANKTNTNTNTNTNNTNTSTPSKNTNTNTNSNTNTNSNTNANQGSSNNNSNSSASA 368
|
|
| TolA |
COG3064 |
Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis]; |
516-568 |
3.48e-03 |
|
Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442298 [Multi-domain] Cd Length: 485 Bit Score: 41.56 E-value: 3.48e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 19115514 516 QISEEEASQRKDAIKLAIQQRIQEKAE----AEAKRKAEEKARLEAEENAKREAEEQ 568
Cdd:COG3064 92 KAAAEKAKAAKEAEAAAAAEKAAAAAEkekaEEAKRKAEEEAKRKAEEERKAAEAEA 148
|
|
| PHA03255 |
PHA03255 |
BDLF3; Provisional |
206-313 |
4.32e-03 |
|
BDLF3; Provisional
Pssm-ID: 165513 [Multi-domain] Cd Length: 234 Bit Score: 40.66 E-value: 4.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 206 VTSNPPHTEEPvAAKPEASSTATKGPRPTTSASNTNTSPANGAPTNKP--STDINTTDPATqTTQVSASNSPALS-GSST 282
Cdd:PHA03255 43 VTTPSPSASGP-STNQSTTLTTTSAPITTTAILSTNTTTVTSTGTTVTpvPTTSNASTINV-TTKVTAQNITATEaGTGT 120
|
90 100 110
....*....|....*....|....*....|.
gi 19115514 283 PSNTSSRSNRQNHGNFSEKRHYDRYGNSHPS 313
Cdd:PHA03255 121 STGVTSNVTTRSSSTTSATTRITNATTLAPT 151
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
40-543 |
4.67e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 41.68 E-value: 4.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 40 EKQAVKPSG-VEPTNtsranaqKKTESTGKITSEADTEKYNSSKSPVNKEGSveKKSSEKSSTNNKPWRGDNTSKPSANS 118
Cdd:pfam03154 22 KKQTASPDGrASPTN-------EDLRSSGRNSPSAASTSSNDSKAESMKKSS--KKIKEEAPSPLKSAKRQREKGASDTE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 119 SAERTSSQHQKpetSSQIGKDNAaPVENVNEKSTSQETAPPVSTVPIQFGSITRNAAiPSKPKVSGNMQNKSGVSSYSSK 198
Cdd:pfam03154 93 EPERATAKKSK---TQEISRPNS-PSEGEGESSDGRSVNDEGSSDPKDIDQDNRSTS-PSIPSPQDNESDSDSSAQQQIL 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 199 SQSVNSSVTSNPPhTEEPVAAKPEASSTATKGPRPTTSASNTNTSPANGAPTNKPSTDINTTDPATQTTQVSASNSPA-- 276
Cdd:pfam03154 168 QTQPPVLQAQSGA-ASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSph 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 277 -----LSGSSTPSNTSSRSNRQ--NHGNFSEKRHYDRYGnshPSYNKYSHYQHGFNYNNSGNNRNESGHPRFRNSRRNYN 349
Cdd:pfam03154 247 pplqpMTQPPPPSQVSPQPLPQpsLHGQMPPMPHSLQTG---PSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQ 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 350 NQGAYPTYMSNgrSANQSPRNN-----PQNVNNGSTPIQIPVSlQTPYGQVYGQPQYIVDPNMVQYG------PILQP-G 417
Cdd:pfam03154 324 RIHTPPSQSQL--QSQQPPREQplppaPLSMPHIKPPPTTPIP-QLPNPQSHKHPPHLSGPSPFQMNsnlpppPALKPlS 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 418 YVPQYYPVYHQTPYTQNFPNmsrsGSQVSDQVVESPnssTLSPRNGFAPIVKQQKKSSALKIVNP----VTHTEVVVPQK 493
Cdd:pfam03154 401 SLSTHHPPSAHPPPLQLMPQ----SQQLPPPPAQPP---VLTQSQSLPPPAASHPPTSGLHQVPSqspfPQHPFVPGGPP 473
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 19115514 494 NASSPNPSETNSRAETPTAAPPQISEEEASQRKDAIKLAIQQRIQEKAEA 543
Cdd:pfam03154 474 PITPPSGPPTSTSSAMPGIQPPSSASVSSSGPVPAAVSCPLPPVQIKEEA 523
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1-288 |
5.31e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 41.44 E-value: 5.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 1 MSSKPPSNTPkfSYARALASSQSNKSNST--KASENNTATAEKQAVKPSGVEPT---NTSRANAQKKTESTGKITSEADT 75
Cdd:pfam05109 473 VTSPTPAGTT--SGASPVTPSPSPRDNGTesKAPDMTSPTSAVTTPTPNATSPTpavTTPTPNATSPTLGKTSPTSAVTT 550
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 76 EKYNSSkSPVNKEGSVEKKSSEKSSTNNKPWRGDNTSKPSANSSAERTSSQhQKPETSSQIGKDNAAPV-----ENVNEK 150
Cdd:pfam05109 551 PTPNAT-SPTPAVTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSP-QANTTNHTLGGTSSTPVvtsppKNATSA 628
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 151 STSQE---TAPPVSTVPIQFGSITRNAAipskPKVSGNmqnksgvssyssKSQSVNSSVTSNPPHTEEPVAAKPEASST- 226
Cdd:pfam05109 629 VTTGQhniTSSSTSSMSLRPSSISETLS----PSTSDN------------STSHMPLLTSAHPTGGENITQVTPASTSTh 692
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19115514 227 --ATKGPRPTTSASNTNTSPANGAPTNKPStDINTTDpATQTTQVSASNSPALSGSSTPSNTSS 288
Cdd:pfam05109 693 hvSTSSPAPRPGTTSQASGPGNSSTSTKPG-EVNVTK-GTPPKNATSPQAPSGQKTAVPTVTST 754
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
215-567 |
5.92e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 41.22 E-value: 5.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 215 EPVAAKPEASSTATKGPRPTTSASNTNTSPANGAPTNKPSTDINTTdPATQTTQVSASNSPAlsgSSTPSNTSSRSNRQN 294
Cdd:PRK10263 318 EPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQPV-PGPQTGEPVIAPAPE---GYPQQSQYAQPAVQY 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 295 HGNFSEkrhydrygnshPSYNKYSHYQHGFNYNNSGNNRNEsgHPRFRNSRRNYNNQGAYPTYMSNGRSANQSPRNNPQN 374
Cdd:PRK10263 394 NEPLQQ-----------PVQPQQPYYAPAAEQPAQQPYYAP--APEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQS 460
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 375 VNNGSTPIQIPVSLQTPYGQvygqPQYIVDPNMVQYGPILQ---PGYVPQYYpvyhqtpYTQNFPNMSRSGSQVSD--QV 449
Cdd:PRK10263 461 TYQTEQTYQQPAAQEPLYQQ----PQPVEQQPVVEPEPVVEetkPARPPLYY-------FEEVEEKRAREREQLAAwyQP 529
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115514 450 VESPNSSTLsprngfapIVKQQKKSSALKIVNPVTHTEVVVPQknASSPNPSETNSRAETPTAAP-----------PQIS 518
Cdd:PRK10263 530 IPEPVKEPE--------PIKSSLKAPSVAAVPPVEAAAAVSPL--ASGVKKATLATGAAATVAAPvfslansggprPQVK 599
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19115514 519 EEEASQ-----------RKD----AIKLAIQQRIQEKAEAEAKRKAEEKARLEAEENAKREAEE 567
Cdd:PRK10263 600 EGIGPQlprpkrirvptRRElasyGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDE 663
|
|
| |
