|
Name |
Accession |
Description |
Interval |
E-value |
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
18-431 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 758.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 18 VVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFSELE 97
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 98 KLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAELGKQSIGTTGKGIGPAYSTKATRSGIRVHHLYHWAEFEARYRKN 177
Cdd:pfam00709 81 ELEERGIDVPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 178 VADLQKRYGAF---EYDVEAELIRYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSSNTTV 254
Cdd:pfam00709 161 LELKNKLLEKLygePLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTTA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 255 GGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTMINGYT 334
Cdd:pfam00709 241 GGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGVT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 335 SLNLTKLDILDALDEIKVAVAYIINGKRIETFPADLDSLEEAEIVYETFPGWKVPTTGITHWDQMPENAKKYIEFIEKFV 414
Cdd:pfam00709 321 GLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEELL 400
|
410
....*....|....*..
gi 19115576 415 GVPITFIGVGPGRDEML 431
Cdd:pfam00709 401 GVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
17-432 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 702.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 17 TVVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFSEL 96
Cdd:smart00788 2 VVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 97 EKLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAELgkqsIGTTGKGIGPAYSTKATRSGIRVHHLYHWAEFEARYRK 176
Cdd:smart00788 82 EELEAKGVDVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLEE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 177 NVAD----LQKRYGAFEYDVEAELIRYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSSNT 252
Cdd:smart00788 158 LLDYknflLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSNT 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 253 TVGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTMING 332
Cdd:smart00788 238 TAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRING 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 333 YTSLNLTKLDILDALDEIKVAVAYIINGKRIETFPADLDSLEEAEIVYETFPGWKVPTTGITHWDQMPENAKKYIEFIEK 412
Cdd:smart00788 318 ITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERIEE 397
|
410 420
....*....|....*....|
gi 19115576 413 FVGVPITFIGVGPGRDEMLV 432
Cdd:smart00788 398 LVGVPVSIISTGPDREQTIV 417
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
17-434 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 671.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 17 TVVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFSEL 96
Cdd:COG0104 2 VVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 97 EKLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAELGKQSIGTTGKGIGPAYSTKATRSGIRVHHLYHWAEFEARYRK 176
Cdd:COG0104 82 DGLEARGVDVRSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLEE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 177 NVAD----LQKRYGAFEYDVEAELIRYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSSNT 252
Cdd:COG0104 162 LLEYknflLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSNT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 253 TVGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTMING 332
Cdd:COG0104 242 TAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRING 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 333 YTSLNLTKLDILDALDEIKVAVAYIINGKRIETFPADLDSLEEAEIVYETFPGWKVPTTGITHWDQMPENAKKYIEFIEK 412
Cdd:COG0104 322 LTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERIEE 401
|
410 420
....*....|....*....|..
gi 19115576 413 FVGVPITFIGVGPGRDEMLVKE 434
Cdd:COG0104 402 LLGVPISIVSVGPDREQTIVRR 423
|
|
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
17-434 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 652.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 17 TVVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFSEL 96
Cdd:PRK01117 4 VVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALLKEI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 97 EKLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAELGKQSIGTTGKGIGPAYSTKATRSGIRVHHLYHWAEFEARYRK 176
Cdd:PRK01117 84 DELEARGVDVRERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEKLEE 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 177 NVAD----LQKRYGAFEYDVEAELIRYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSSNT 252
Cdd:PRK01117 164 NLEYknflLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTSSNT 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 253 TVGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTMING 332
Cdd:PRK01117 244 TAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAVRVNG 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 333 YTSLNLTKLDILDALDEIKVAVAYIINGKRIETFPADLDSLEEAEIVYETFPGWKVPTTGITHWDQMPENAKKYIEFIEK 412
Cdd:PRK01117 324 LTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIKRIEE 403
|
410 420
....*....|....*....|..
gi 19115576 413 FVGVPITFIGVGPGRDEMLVKE 434
Cdd:PRK01117 404 LTGVPISIISTGPDRDQTIILR 425
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
18-432 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 594.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 18 VVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFSELE 97
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 98 KLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAELGKQSIGTTGKGIGPAYSTKATRSGIRVHHLYH----WAEFEAR 173
Cdd:TIGR00184 81 YLEKRGISVRDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDdeafAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 174 YRKNVADLQKRYGAFEYDVEAELIRYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSSNTT 253
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 254 VGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTMINGY 333
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 334 TSLNLTKLDILDALDEIKVAVAYIINGKRIETFPADLDSLEEAEIVYETFPGWKVPTTGITHWDQMPENAKKYIEFIEKF 413
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEEL 400
|
410
....*....|....*....
gi 19115576 414 VGVPITFIGVGPGRDEMLV 432
Cdd:TIGR00184 401 TGVPVTIISTGPEREQTID 419
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
17-432 |
0e+00 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 541.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 17 TVVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFSEL 96
Cdd:cd03108 3 TVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFEEI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 97 EKLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAELGKQSIGTTGKGIGPAYSTKATRSGIRVHHlyhwaefearyrk 176
Cdd:cd03108 83 EELEKKGIDVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD------------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 177 nvadlqkrygafeydveaelirykelaqrlkPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSSNTTVGG 256
Cdd:cd03108 150 -------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSSNTTAGG 198
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 257 VCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTMINGYTSL 336
Cdd:cd03108 199 VCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRINGLTEL 278
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 337 NLTKLDIldaldeikvavayiingkrietfpadldsleeaeivyetfpgwkvpttgithwdqmpeNAKKYIEFIEKFVGV 416
Cdd:cd03108 279 ALTKLDV----------------------------------------------------------NAQKYIERIEELLGV 300
|
410
....*....|....*.
gi 19115576 417 PITFIGVGPGRDEMLV 432
Cdd:cd03108 301 PITYISVGPDREQTII 316
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
16-332 |
9.12e-28 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 111.69 E-value: 9.12e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 16 ITVVLGSQWGDEGKGKLVDILC--DNVDVCARCqGGNNAGHTIV-ANGVTYDFHILPSGLVNPKC-QNLIGSGVVVYLPA 91
Cdd:NF038379 1 VDVVVDGQFGSTGKGLIAGYLAerAAPDVVVRA-AGPNAGHTYIdDEGRKFVHRMLPNGIVSPPLkQVLIGPGSEIDLEV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 92 FFSELEKLEQKGLKCRDRIFISDRAHLVFDYHQRadalnEAELGKQS-IGTTGKGIGPAystkatrsgirvhhlyhwaeF 170
Cdd:NF038379 80 LREEIEELEDAGHDVGKRLLIHEQATVIELHKHV-----EEEAGPMTkIGSTKKGIGAA--------------------R 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 171 EARYRKNVADLQkrygafeyDVEAELIRYKELAQRLKPFVIDAVAFMYE-ALQSKKRILVEGANALMLDLDFGTYPFVTS 249
Cdd:NF038379 135 AAKIRRNPSTLG--------DAEGDFGEGAVRDQPWEIAERVVDNALYDfALQAAERIQIEGTQGYSLGLHAGFYPYCTS 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 250 SNTTVGGVCTGLGVPPQ--RIANSIGVVKAYTTRVGA-----GPFPTE-QLNEIGdhlqsVGREVGVTTGRKRRCGWLDL 321
Cdd:NF038379 207 RDCTPADFLADAGIPLPnvDAFKVVGTARTYPIRVAGwsgnsYPDQGEtTWEELG-----LPEELTTVTKKVRRVGTFSA 281
|
330
....*....|.
gi 19115576 322 VVVKYSTMING 332
Cdd:NF038379 282 EQVREAVQANG 292
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
18-431 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 758.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 18 VVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFSELE 97
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 98 KLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAELGKQSIGTTGKGIGPAYSTKATRSGIRVHHLYHWAEFEARYRKN 177
Cdd:pfam00709 81 ELEERGIDVPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 178 VADLQKRYGAF---EYDVEAELIRYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSSNTTV 254
Cdd:pfam00709 161 LELKNKLLEKLygePLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTTA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 255 GGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTMINGYT 334
Cdd:pfam00709 241 GGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGVT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 335 SLNLTKLDILDALDEIKVAVAYIINGKRIETFPADLDSLEEAEIVYETFPGWKVPTTGITHWDQMPENAKKYIEFIEKFV 414
Cdd:pfam00709 321 GLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEELL 400
|
410
....*....|....*..
gi 19115576 415 GVPITFIGVGPGRDEML 431
Cdd:pfam00709 401 GVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
17-432 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 702.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 17 TVVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFSEL 96
Cdd:smart00788 2 VVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 97 EKLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAELgkqsIGTTGKGIGPAYSTKATRSGIRVHHLYHWAEFEARYRK 176
Cdd:smart00788 82 EELEAKGVDVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLEE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 177 NVAD----LQKRYGAFEYDVEAELIRYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSSNT 252
Cdd:smart00788 158 LLDYknflLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSNT 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 253 TVGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTMING 332
Cdd:smart00788 238 TAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRING 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 333 YTSLNLTKLDILDALDEIKVAVAYIINGKRIETFPADLDSLEEAEIVYETFPGWKVPTTGITHWDQMPENAKKYIEFIEK 412
Cdd:smart00788 318 ITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERIEE 397
|
410 420
....*....|....*....|
gi 19115576 413 FVGVPITFIGVGPGRDEMLV 432
Cdd:smart00788 398 LVGVPVSIISTGPDREQTIV 417
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
17-434 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 671.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 17 TVVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFSEL 96
Cdd:COG0104 2 VVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 97 EKLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAELGKQSIGTTGKGIGPAYSTKATRSGIRVHHLYHWAEFEARYRK 176
Cdd:COG0104 82 DGLEARGVDVRSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLEE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 177 NVAD----LQKRYGAFEYDVEAELIRYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSSNT 252
Cdd:COG0104 162 LLEYknflLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSNT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 253 TVGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTMING 332
Cdd:COG0104 242 TAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRING 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 333 YTSLNLTKLDILDALDEIKVAVAYIINGKRIETFPADLDSLEEAEIVYETFPGWKVPTTGITHWDQMPENAKKYIEFIEK 412
Cdd:COG0104 322 LTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERIEE 401
|
410 420
....*....|....*....|..
gi 19115576 413 FVGVPITFIGVGPGRDEMLVKE 434
Cdd:COG0104 402 LLGVPISIVSVGPDREQTIVRR 423
|
|
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
17-434 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 652.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 17 TVVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFSEL 96
Cdd:PRK01117 4 VVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALLKEI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 97 EKLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAELGKQSIGTTGKGIGPAYSTKATRSGIRVHHLYHWAEFEARYRK 176
Cdd:PRK01117 84 DELEARGVDVRERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEKLEE 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 177 NVAD----LQKRYGAFEYDVEAELIRYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSSNT 252
Cdd:PRK01117 164 NLEYknflLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTSSNT 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 253 TVGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTMING 332
Cdd:PRK01117 244 TAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAVRVNG 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 333 YTSLNLTKLDILDALDEIKVAVAYIINGKRIETFPADLDSLEEAEIVYETFPGWKVPTTGITHWDQMPENAKKYIEFIEK 412
Cdd:PRK01117 324 LTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIKRIEE 403
|
410 420
....*....|....*....|..
gi 19115576 413 FVGVPITFIGVGPGRDEMLVKE 434
Cdd:PRK01117 404 LTGVPISIISTGPDRDQTIILR 425
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
3-433 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 649.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 3 SVRETGVNVSNDGITVVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIG 82
Cdd:PTZ00350 1 SFEHDSLNGLKSKVVVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 83 SGVVVYLPAFFSELEKLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAELGK--QSIGTTGKGIGPAYSTKATRSGIR 160
Cdd:PTZ00350 81 NGVVIHLPSLLEEIEQLTKKGINLLGRLYISDRAHLVFDLHQAIDGIQESEKGKggTQIGTTKRGIGPCYSTKASRTGLR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 161 VHHLYHWAEFEARYRKNVADLQKRYGAFEYDVEAELIRYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLD 240
Cdd:PTZ00350 161 VGDLLNFETFEKKYRKLVEKLQEQYNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIKEGKRVLVEGANATMLDID 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 241 FGTYPFVTSSNTTVGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLD 320
Cdd:PTZ00350 241 FGTYPYVTSSNTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 321 LVVVKYSTMINGYTSLNLTKLDILDALDEIKVAVAYIINGKRIE--TFPADLDSLEEAEIVYETFPGWKVPTTGITHWDQ 398
Cdd:PTZ00350 321 IPALRYVQMINGFDSINLTKLDVLSGLKEIKICVNYKNKGTGLEigRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEE 400
|
410 420 430
....*....|....*....|....*....|....*
gi 19115576 399 MPENAKKYIEFIEKFVGVPITFIGVGPGRDEMLVK 433
Cdd:PTZ00350 401 LPENAQKYVLFIEELLGVPIVWIGVGPNRENMIVK 435
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
14-433 |
0e+00 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 638.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 14 DGITVVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIV-ANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAF 92
Cdd:PLN02513 2 SQVSAVLGTQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYnDEGKKFALHLVPSGILNEKTTCVIGNGVVVHLPGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 93 FSELEKLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAELGKQSIGTTGKGIGPAYSTKATRSGIRVHHLYHWAEFEA 172
Cdd:PLN02513 82 FEEIDGLESNGVSCEGRLLVSDRAHLLFDFHQEVDGLREAELAGSKIGTTKRGIGPAYSSKATRNGLRVGDLRHMDTFAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 173 RYRKNVADLQKRYGAFEYD---VEAELIRYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTS 249
Cdd:PLN02513 162 KLRELLADAAARFEGFEYDasmVEEEVEAYKKFAERLEPFITDTVHYLNEAIQAGKKILVEGAQATMLDIDFGTYPFVTS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 250 SNTTVGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTM 329
Cdd:PLN02513 242 SNPSAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTELFGELGDLLREAGQEFGTTTGRPRRCGWLDIVALKYSCQ 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 330 INGYTSLNLTKLDILDALDEIKVAVAY-IINGKRIETFPADLDSLEEAEIVYETFPGWKVPTTGITHWDQMPENAKKYIE 408
Cdd:PLN02513 322 INGFTSLNLTKLDVLSGLPEIKIGVAYkTPDGKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPAAAQAYVE 401
|
410 420
....*....|....*....|....*
gi 19115576 409 FIEKFVGVPITFIGVGPGRDEMLVK 433
Cdd:PLN02513 402 RIEELVGVPVHYIGVGPGRDALIVK 426
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
18-432 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 594.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 18 VVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFSELE 97
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 98 KLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAELGKQSIGTTGKGIGPAYSTKATRSGIRVHHLYH----WAEFEAR 173
Cdd:TIGR00184 81 YLEKRGISVRDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDdeafAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 174 YRKNVADLQKRYGAFEYDVEAELIRYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSSNTT 253
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 254 VGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTMINGY 333
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 334 TSLNLTKLDILDALDEIKVAVAYIINGKRIETFPADLDSLEEAEIVYETFPGWKVPTTGITHWDQMPENAKKYIEFIEKF 413
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEEL 400
|
410
....*....|....*....
gi 19115576 414 VGVPITFIGVGPGRDEMLV 432
Cdd:TIGR00184 401 TGVPVTIISTGPEREQTID 419
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
17-432 |
0e+00 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 541.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 17 TVVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFSEL 96
Cdd:cd03108 3 TVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFEEI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 97 EKLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAELGKQSIGTTGKGIGPAYSTKATRSGIRVHHlyhwaefearyrk 176
Cdd:cd03108 83 EELEKKGIDVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD------------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 177 nvadlqkrygafeydveaelirykelaqrlkPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSSNTTVGG 256
Cdd:cd03108 150 -------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSSNTTAGG 198
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 257 VCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTMINGYTSL 336
Cdd:cd03108 199 VCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRINGLTEL 278
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 337 NLTKLDIldaldeikvavayiingkrietfpadldsleeaeivyetfpgwkvpttgithwdqmpeNAKKYIEFIEKFVGV 416
Cdd:cd03108 279 ALTKLDV----------------------------------------------------------NAQKYIERIEELLGV 300
|
410
....*....|....*.
gi 19115576 417 PITFIGVGPGRDEMLV 432
Cdd:cd03108 301 PITYISVGPDREQTII 316
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
17-432 |
1.17e-127 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 375.83 E-value: 1.17e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 17 TVVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFSEL 96
Cdd:PRK13787 4 SLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQTICVIGNGVVLDPLFFIEEC 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 97 EKLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAELGKQ-SIGTTGKGIGPAYSTKATRSGIRVHHLYHwAEFEARYr 175
Cdd:PRK13787 84 DRLQKEGFPVKDKLLLSDACHLLFPYHSQIDSARETTSSQEhKIGTTKKGIGICYADKMMRTGLRVGDLLD-KSYKRRL- 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 176 KNVADLQKRYGAFEYDVEAelIRYKELAQRLKPF-------VIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVT 248
Cdd:PRK13787 162 KHLVDEKNRELDKLYGMPP--VSYNDINDGLKFFlskvgknIINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 249 SSNTTVGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYST 328
Cdd:PRK13787 240 SSNPTTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEVLRQKGGEFGATTGRPRRCGWFDVEMLKHSV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 329 MINGYTSLNLTKLDILDALDEIKVAVAYIINGKRIETFPAdlDSLEEAEIVYETFPGWKVPTTGITHWDQMPENAKKYIE 408
Cdd:PRK13787 320 RINGITSIALTKIDILSDYDTIPVAVGYKLNGKTLDCFPS--QGLEKVEPLYEEFPGWKDDISGINEFQKLPEKCKNYIS 397
|
410 420
....*....|....*....|....
gi 19115576 409 FIEKFVGVPITFIGVGPGRDEMLV 432
Cdd:PRK13787 398 ALEKWIGVKINLVSTGPDRKDTII 421
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
17-434 |
1.11e-126 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 372.98 E-value: 1.11e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 17 TVVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSG-LVNPKCqnLIGSGVVVYLPAFFSE 95
Cdd:PRK13786 3 TIITGAQFGDEGKGKIVDLLAKDYDIVARFQGGDNAGHTVKVGDEVYKLHLIPSGfLLDARV--LIGPGVVLNPEVLAEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 96 LEKLEQKGLKCR-DRIFISDRAHLVFDYHQRADALNEAELgKQSIGTTGKGIGPAYSTKATRSGIRVHHLYHWAEFEARY 174
Cdd:PRK13786 81 IDMLEKHGVKVDaEKLGIDAKTSIIMPYHIELDGLRESAR-TEKIGTTKRGIGFAYIDKIARDEVRMSDLVDKERLMRRL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 175 RKNVADLQKRYGAFEYD----VEAELI-RYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTS 249
Cdd:PRK13786 160 EELAPQKEKEIKELGGDpsivRDEALIdKYLELGRQLAPYITDVSYEINKALDEGKSVLAEGAQGTHLDVIHGTQKFVTS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 250 SNTTVGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTM 329
Cdd:PRK13786 240 SSTIAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTELKDEAGEHLQDVGGEFGTTTGRPRRCGWFDLPLLKKAIY 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 330 INGYTSLNLTKLDILDALDEIKVAVAYIINGKRIETFPADLDSLEEAEIVYETFPGWKVPTTGITHWDQMPENAKKYIEF 409
Cdd:PRK13786 320 LNGYTEIALTKLDVLTGLDPIKICVGYELDGEILDYPPELTSDLARCVPVYEELEGWSTDLTEVKAYEDLPENARNYVER 399
|
410 420
....*....|....*....|....*
gi 19115576 410 IEKFVGVPITFIGVGPGRDEMLVKE 434
Cdd:PRK13786 400 LEELMGVPIKYISVGPGREQTFKKE 424
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
18-430 |
2.35e-122 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 361.34 E-value: 2.35e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 18 VVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFSELE 97
Cdd:PRK13783 4 VIVGLQWGDEGKGKVVTYLSRYYDIVVRYSGGANAGHTVNYGDFKVVHHLLPSADFKKNVGAAIGNGVVLDLEVLVEELE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 98 KLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAELGKQsIGTTGKGIGPAYSTKATRSGIRVHHLYHWAEFEARYRKN 177
Cdd:PRK13783 84 ELKEKFPDYSGRIFISELAHVVLPVHKELDEIIESVRKNA-IGTTKRGIGPAYADKVMRVGVRLADLFDEEKLREFLEKI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 178 VADLQKRYGaFEYDVEAELIRYKELAQRLKPFVIDAVAfMYEALQsKKRILVEGANALMLDLDFGTYPFVTSSNTTVGGV 257
Cdd:PRK13783 163 LSLYKKLYG-IEFDVEKMMEDLLTFYEKIKDLVVSPVE-IKRILE-EKSVLFEGTQGVLLDLDVGTYPYVTSSNCSTTGV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 258 CTGLGVPPQrIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTMINGYTSLN 337
Cdd:PRK13783 240 SAGMGFPVK-VDEVIGVFKAYTTRVGEGPFPTELFGEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLRYAIEVSGVDSLV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 338 LTKLDILDALDEIKVAVAYIINGKRIETfPADLDSLEEAEIVYETFPGWKvpttgiTHWDQmpeNAKKYIEFIEKFVGVP 417
Cdd:PRK13783 319 MTKADVLNGFEKIKVCVRYEIGGKEVRD-PSSLRDLEKAEPVYEEFDGWK------SLEDK---NFLKFVDFIERETGRK 388
|
410
....*....|...
gi 19115576 418 ITFIGVGPGRDEM 430
Cdd:PRK13783 389 IAYISTGPKIEEI 401
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
15-429 |
7.39e-122 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 360.28 E-value: 7.39e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 15 GITVVlGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFS 94
Cdd:PRK13788 3 GIAII-GAQWGDEGKGKVVDALAPEADFVVRYQGGANAGHTVVAKGKTFKLNLLPSGVLHPHATSVLGDGMVIDPFRFAE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 95 ELEKLEQKGLKcrDRIFISDRAHLVFDYHQRADAlneaelGKQSIGTTGKGIGPAYSTKATRSGIRVHHLYHWAEFEARY 174
Cdd:PRK13788 82 ERENLRAGGLN--PKLLISERAHLVLPHHKYVDG------RKNFVGTTGRGIGPAYSDRARRVGIRFGDLLDEAVLRERV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 175 RKNVA---DLQKRYG-AFEYDVEAELIRYKELaqrLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSS 250
Cdd:PRK13788 154 ERLLEakpNSTREAGwDTVEKALADLAPMREI---LLPFIADTGSLLREAIREGKRVLFEGAQATLLDLNYGTYPYVTSS 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 251 NTTVGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVG----REVGVTTGRKRRCGWLDLVVVKY 326
Cdd:PRK13788 231 HPTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEVFGEMAIRLRGKGgnpwDEFGTTTGRARRVGWLDLVLLKY 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 327 STMINGYTSLNLTKLDILDALDEIKVAVAYiingkrietfpadldsLEEAEIVYETFPGWKvPTTGITHWDQMPENAKKY 406
Cdd:PRK13788 311 ACEVNGFDGLVLTKLDVLSGLEKVKVCVEY----------------DDDGQPVYKELPGWG-DLDGVKSREALPKEAQAY 373
|
410 420
....*....|....*....|...
gi 19115576 407 IEFIEKFVGVPITFIGVGPGRDE 429
Cdd:PRK13788 374 LELIEETTGVPVVMFSTSPRRED 396
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
16-434 |
2.47e-112 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 337.50 E-value: 2.47e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 16 ITVVlGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCqNLIGSGVVVYLPAFFSE 95
Cdd:PRK13785 3 VTIV-GSQLGDEGKGGVVDLYGDAADVVVRYQGGDNAGHTVVHGGEEYKLSLVPSGAVRGKI-GVLGNGCVVNPETLFDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 96 LEKLEQKGLKCRDRIfiSDRAHLVFDYHQRADALNEAELGK--QSIGTTGKGIGPAYSTKATRSGIRVHHLYHWAEFEAR 173
Cdd:PRK13785 81 IDALRERGLDPDVRV--AERAHVILPYHRVLDGIEEEAKSDsdLEVGTTGRGIGPTYEDKAGRRGVRVGDLLDPDVLRDR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 174 YR----------KNVADLQKRYGAFEYDVEAELIRYKELAQRLKP--FVIDAVAFMYEALQSKKRILVEGANALMLDLDF 241
Cdd:PRK13785 159 LEyvvpqkralaEDVYGLDASETPEAFDVDALFEEYREYGERLAEedMTVNAGDFLAERIDDGDNVMLEGAQGTSIDIDH 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 242 GTYPFVTSSNTTVGGVCTGLGVPPQRIANS--IGVVKAYTTRVGAGPFPTE---------------QLNEIGDHLQSVGR 304
Cdd:PRK13785 239 GNYPYVTSSNPTAGGAATGTGLGPTVVGQGevVGIVKAYLSRVGSGPLPTElggvegdtpdeggrpDEEELATYIREEGG 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 305 EVGVTTGRKRRCGWLDLVVVKYSTMINGYTSLNLTKLDILDALDEIKVAVAYIINGKRIETFPADLDSLEEAEIVYETFP 384
Cdd:PRK13785 319 EYGTVTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYELDGEELLTMPATTERWARCEPNFRSFD 398
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 19115576 385 GWK------VPTTGithWDQMPENAKKYIEFIEKFVGVPITFIGVGPGRDEMLVKE 434
Cdd:PRK13785 399 GWPevdwaaVAEEG---YDALPENARTYLEYVSDELDTPIYAVGVGPGREETVVLE 451
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
18-434 |
5.55e-103 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 312.72 E-value: 5.55e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 18 VVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFSELE 97
Cdd:PRK13784 5 VIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALDEEIT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 98 KLEQKGLKCR-DRIFISDRAHLVFDYHQRADALNEAELGKQsIGTTGKGIGPAYSTKATRSGIRVHHLYHWAEFEARYRK 176
Cdd:PRK13784 85 RLQAKGIAISaENLFVSESCTIITSYHKLLDAVRESNTSEK-IGTTGKGIGPAYEDKVSRKGIKFKHLFDKDLLRSRLAI 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 177 NVAD---LQKRYGAFEY-DVEAELIRYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSSNT 252
Cdd:PRK13784 164 SLAEketLFRDLYKVEYpTLEQEFDKLFALGQKLKQYAADTFSIIDQAIAAGKNVVYEGAQGVLLDVDYGTYPFVTSSNT 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 253 TVGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTMING 332
Cdd:PRK13784 244 SVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLDLPLLKYSAKCSN 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 333 YTSLNLTKLDILDALDEIKVAVAYIINGKRIE-TFPA-DLDSLEEAEIVYETFPGWKVPTTgithwDQMPENAKKYIEFI 410
Cdd:PRK13784 324 LTSIALTKVDVLSDMDTLKVCIGYKYEGKEIYcAYPGiDLYKVEPILVEMEPFSIDETVTK-----DNMPAALKTYLKTI 398
|
410 420
....*....|....*....|....
gi 19115576 411 EKFVGVPITFIGVGPGRDEMLVKE 434
Cdd:PRK13784 399 ENHVGIPISSLAYGPSREQILFFE 422
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
17-425 |
9.79e-85 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 262.51 E-value: 9.79e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 17 TVVLGSQWGDEGKGKLVDILC--DNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFS 94
Cdd:PRK04293 4 TIVVGGFFGDEGKGKIIAYLAlkDKPSIIARGGVGPNAGHTVEYNGKKYGLRMIPSGFVNKDAKLAIGAGVLVDPEVLLK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 95 ELEKleqkgLKCRDRIFISDRAHLVFDYHQRADALNEaELGKQsIGTTGKGIGPAYSTKATRsgirvhhlyhwaefeary 174
Cdd:PRK04293 84 EVEE-----LNVGGRVFVDYRCGIIEEKHVEEDRSDE-HLSKK-IGSTGTGCGPANADRVLR------------------ 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 175 rknVADLQKrygafeyDVEAelirykelaqrLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSSNTTV 254
Cdd:PRK04293 139 ---RLKLAK-------DVEE-----------LEKYLTDVPEEVNEALDRGENVLIEGTQGFGLSLYYGTYPYVTSKDTTA 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 255 GGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVgrEVGVTTGRKRRCGWLDLVVVKYSTMINGYT 334
Cdd:PRK04293 198 SGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTELSLEEAEKLGLV--EYGTVTGRRRRVGPFDFELARRAARINGAT 275
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 335 SLNLTKLDILDaldeikvavayiingkrietfpadldslEEAeivyetfpgwkvptTGITHWDQMPENAKKYIEFIEKFV 414
Cdd:PRK04293 276 QIAITKLDKLD----------------------------KEA--------------YGVTEYDKLPPEAKKFIEEIEEEL 313
|
410
....*....|.
gi 19115576 415 GVPITFIGVGP 425
Cdd:PRK04293 314 GVPVTLISTGP 324
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
16-332 |
9.12e-28 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 111.69 E-value: 9.12e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 16 ITVVLGSQWGDEGKGKLVDILC--DNVDVCARCqGGNNAGHTIV-ANGVTYDFHILPSGLVNPKC-QNLIGSGVVVYLPA 91
Cdd:NF038379 1 VDVVVDGQFGSTGKGLIAGYLAerAAPDVVVRA-AGPNAGHTYIdDEGRKFVHRMLPNGIVSPPLkQVLIGPGSEIDLEV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 92 FFSELEKLEQKGLKCRDRIFISDRAHLVFDYHQRadalnEAELGKQS-IGTTGKGIGPAystkatrsgirvhhlyhwaeF 170
Cdd:NF038379 80 LREEIEELEDAGHDVGKRLLIHEQATVIELHKHV-----EEEAGPMTkIGSTKKGIGAA--------------------R 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 171 EARYRKNVADLQkrygafeyDVEAELIRYKELAQRLKPFVIDAVAFMYE-ALQSKKRILVEGANALMLDLDFGTYPFVTS 249
Cdd:NF038379 135 AAKIRRNPSTLG--------DAEGDFGEGAVRDQPWEIAERVVDNALYDfALQAAERIQIEGTQGYSLGLHAGFYPYCTS 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 250 SNTTVGGVCTGLGVPPQ--RIANSIGVVKAYTTRVGA-----GPFPTE-QLNEIGdhlqsVGREVGVTTGRKRRCGWLDL 321
Cdd:NF038379 207 RDCTPADFLADAGIPLPnvDAFKVVGTARTYPIRVAGwsgnsYPDQGEtTWEELG-----LPEELTTVTKKVRRVGTFSA 281
|
330
....*....|.
gi 19115576 322 VVVKYSTMING 332
Cdd:NF038379 282 EQVREAVQANG 292
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
16-431 |
5.70e-18 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 86.26 E-value: 5.70e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 16 ITVVLGSQWGDEGKGKLVDI-----LCDNVdvcARCQGGNNAGHTIVAN-GVTYDFHILPSGLVNPKCQNLIGSGVVVYl 89
Cdd:PTZ00351 171 VIMVAGAFFGDEGKGKTVDAvahhpLCTCI---ARVNSGENAGHTVYDKaGRKFVFNLAPSGLLLPGKRNYIGPECVMD- 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 90 PAFFSELE--KLEQKGLKCRDRIFISDRAhLVFDYHQRADALneaelGKQSIGTTGKGIGPAYSTKATRSGIRVHHLYHw 167
Cdd:PTZ00351 247 PVSFMEKEiiQLIDAGIDYRDRLFIGNVC-IVTPYHKLLDLL-----GSAANSSTLKGMAPVHGSKVMKRGIRLDHIFN- 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 168 aEFEARYRKNVADLQKRYGAFEYD--VEAELIRY-----KELAQRLKPFVI------DAVAFM----------------- 217
Cdd:PTZ00351 320 -DDETLRKRLEKDMDTYLGLLKVKnlSDADVVRLcreenSDGVVRVPDYVIafaqakDKVEFLvklyrdrvrhnpdfpar 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 218 ----YE---ALQSKKRILVEGANALML-DLDFGTYPFVTSSNTTVGGVCTGLGVPPQRIANSI-GVVKAY-TTRVGAG-- 285
Cdd:PTZ00351 399 cdvtYElhaAVLRGEKVLLEGPQSYWLsNARTKFWESTTSADTTAAGLLAASQLNFQKFKSVVlNVHKAPgSSRVGIGac 478
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 286 -----------------------------------------PF------------PTEQLNEIGDHLQSVGR-------- 304
Cdd:PTZ00351 479 pssfvpqdyfsaqniktlrdlpsatcanfeavqrtlfrdgfPHsndkarhngimaPVEYSDETGDYNIGVAMaiasaqhh 558
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115576 305 -EVGVTTGRKRRCGWLDLVVVKYSTMINGyTSLNLTKLDILDALDEIKVAVAYII---NGKRIETF-----PADL----D 371
Cdd:PTZ00351 559 gECGAVTKKPRVCGFFDCVLQHEVNSIQG-PYLTISALDRGDEYDKVGVTIAYVYynpEGKQVDVNghvykNGDIiragD 637
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 19115576 372 SLEEAEIVYETFP------GWK---VPTTGITHWDQMPENAKKYIEFIEKFVGVPITFIGVGPGRDEML 431
Cdd:PTZ00351 638 PVPSEPALYHCHPivklidGWRdnpIAAAKRRRNAPLPRGVCELLSTIEYFTNCKILSIGNGPNGDDII 706
|
|
| |
