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Conserved domains on  [gi|429243777|ref|NP_594969|]
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Maf-like protein Ifs1 [Schizosaccharomyces pombe]

Protein Classification

nucleoside triphosphate pyrophosphatase( domain architecture ID 10088068)

Maf family nucleoside triphosphate (NTP) pyrophosphatase hydrolyzes nucleotides to their respective monophosphates

CATH:  3.90.950.10
EC:  3.6.1.-
Gene Ontology:  GO:0047429|GO:0009146|GO:0000166
PubMed:  8387996
SCOP:  4000518

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 32-227 1.15e-77

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


:

Pssm-ID: 238310  Cd Length: 180  Bit Score: 231.98  E-value: 1.15e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  32 IILASGSPRRKQLFEQMGFPnVETCVSGFPEDLNKsmYITPWEYAADTSVQKAIAVYEKLAAeedsPDIVVSADTILILD 111
Cdd:cd00555    1 LILASASPRRRELLEQLGIP-FEVVPSDIDETPIK--GESPEDYVLRLAEAKAEAVAARLPP----DALVIGADTVVVLD 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 112 SEIMEKPNDPKHHLAMLKKLRNSKtpHKVFTAVSVIvpmevpiHPGYVMKTHLEETQVKFDPsITDEFLEAYVRCGEGSD 191
Cdd:cd00555   74 GRILGKPKDREEAREMLKRLSGRT--HEVYTGVALI-------DPGGKLVTDVESTKVRFRE-LSDEEIEAYVASGEPLD 143

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 429243777 192 KAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKL 227
Cdd:cd00555  144 KAGAYGIQGLGGALIERIEGDYSNVVGLPLPELLKL 179
 
Name Accession Description Interval E-value
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 32-227 1.15e-77

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 231.98  E-value: 1.15e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  32 IILASGSPRRKQLFEQMGFPnVETCVSGFPEDLNKsmYITPWEYAADTSVQKAIAVYEKLAAeedsPDIVVSADTILILD 111
Cdd:cd00555    1 LILASASPRRRELLEQLGIP-FEVVPSDIDETPIK--GESPEDYVLRLAEAKAEAVAARLPP----DALVIGADTVVVLD 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 112 SEIMEKPNDPKHHLAMLKKLRNSKtpHKVFTAVSVIvpmevpiHPGYVMKTHLEETQVKFDPsITDEFLEAYVRCGEGSD 191
Cdd:cd00555   74 GRILGKPKDREEAREMLKRLSGRT--HEVYTGVALI-------DPGGKLVTDVESTKVRFRE-LSDEEIEAYVASGEPLD 143

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 429243777 192 KAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKL 227
Cdd:cd00555  144 KAGAYGIQGLGGALIERIEGDYSNVVGLPLPELLKL 179
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 32-231 5.62e-66

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 201.86  E-value: 5.62e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777   32 IILASGSPRRKQLFEQMGFPnVETCVSGFPEDLNKSmYITPWEYAADTSVQKAIAvyeklaaeedspdIVVSADTILILd 111
Cdd:pfam02545   1 LILASASPRRRELLEQLGIE-FEVVPSDIDETPLKE-DPAPEEYVLRLARAKAEA-------------LVIGADTVVVL- 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  112 seIMEKPNDPKHHLAMLKKLRNSKtpHKVFTAVSVIVPMEVPIHpgyvmKTHLEETQVKFDPsITDEFLEAYVRCGEGSD 191
Cdd:pfam02545  65 --ILGKPKDEEEARAMLKRLSGRT--HEVYTGVALINPGGGTGG-----VSFVETTRVTFRP-LSDEEIEAYVATGEPLD 134

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 429243777  192 KAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKLMEEA 231
Cdd:pfam02545 135 KAGAYGIQGLGAALVERIEGDYSNVVGLPLIELLRLLREL 174
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 30-231 4.92e-65

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 199.88  E-value: 4.92e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  30 KRIILASGSPRRKQLFEQMGFPnVETCVSGFPEDLNKSMyiTPWEYAADTSVQKAIAVYEKLAaeedsPDIVVSADTILI 109
Cdd:COG0424    1 PKLILASASPRRRELLEQLGLP-FEVVPPDIDETPLPGE--SPEELVLRLARAKAEAVAARLP-----DALVLGADTVVV 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 110 LDSEIMEKPNDPKHHLAMLKKLRNSKtpHKVFTAVSVIvpmevpiHPGYVMKTHLEETQVKFDPsITDEFLEAYVRCGEG 189
Cdd:COG0424   73 LDGRILGKPADAEEARAMLRRLSGRT--HRVHTGVALI-------DPGGRLWTRVVTTRVTFRP-LSDAEIEAYLATGEP 142

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 429243777 190 SDKAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKLMEEA 231
Cdd:COG0424  143 LDKAGAYGIQGLGAALVERIEGSYSNVVGLPLIELLELLREL 184
PRK00648 PRK00648
Maf-like protein; Reviewed
 28-230 8.59e-48

Maf-like protein; Reviewed


Pssm-ID: 234807  Cd Length: 191  Bit Score: 156.22  E-value: 8.59e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  28 KDKRIILASGSPRRKQLFEQMGFPNveTCVSGFPEDLNKSMYITPWEYAADTSVQKAIAVYEKLAAEEdspdIVVSADTI 107
Cdd:PRK00648   1 MKYKIILASSSPRRKEILEGFRIPF--EVVPSPFVEESYPYSLDPEEITLELARLKAEAVRSDLFPDE----LIITADTI 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 108 LILDSEIMEKPNDPKHHLAMLKKLRNsKTpHKVFTAVSVIvpmevpiHPGYVMKTHlEETQVKFDPsITDEFLEAYVRCG 187
Cdd:PRK00648  75 VWYDGKVLGKPKDEEEAVEMLRTLSG-KT-HEVITGVCLL-------HNGKLLSGS-ETTQVTFRE-LSDEEIEYYIDTY 143

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 429243777 188 EGSDKAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKLMEE 230
Cdd:PRK00648 144 KPLDKAGAYGIQEWGGLIVKKIEGSYYNVMGLPIQTLYEELKE 186
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 30-228 1.15e-47

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 155.63  E-value: 1.15e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777   30 KRIILASGSPRRKQLFEQMGFPnVETCVSGFPEDLNKSMyiTPWEYAADTSVQKAIAVYEKLaaeedsPD-IVVSADTIL 108
Cdd:TIGR00172   3 KELILASQSPRRKELLEELGIS-FEQIVSEFDEKSLKTT--SPRELVYRLAKEKAQAVAELL------ADaLIIGADTVV 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  109 ILDSEIMEKPNDPKHHLAMLKKLRNSKtpHKVFTAVSVIVPmevpihpgYVMKTHLEETQVKFDpSITDEFLEAYVRCGE 188
Cdd:TIGR00172  74 ILDGEIYGKPKDKEEAAEFLRKLSGQE--HEVYTAVALIDS--------VHLLTFLDVTKVHFR-ALDPEEIEKYVESGE 142

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 429243777  189 GSDKAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKLM 228
Cdd:TIGR00172 143 PLEKAGAFGIEGFGAPLIKKIDGDYSNVVGLPLEKLLGAL 182
 
Name Accession Description Interval E-value
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 32-227 1.15e-77

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 231.98  E-value: 1.15e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  32 IILASGSPRRKQLFEQMGFPnVETCVSGFPEDLNKsmYITPWEYAADTSVQKAIAVYEKLAAeedsPDIVVSADTILILD 111
Cdd:cd00555    1 LILASASPRRRELLEQLGIP-FEVVPSDIDETPIK--GESPEDYVLRLAEAKAEAVAARLPP----DALVIGADTVVVLD 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 112 SEIMEKPNDPKHHLAMLKKLRNSKtpHKVFTAVSVIvpmevpiHPGYVMKTHLEETQVKFDPsITDEFLEAYVRCGEGSD 191
Cdd:cd00555   74 GRILGKPKDREEAREMLKRLSGRT--HEVYTGVALI-------DPGGKLVTDVESTKVRFRE-LSDEEIEAYVASGEPLD 143

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 429243777 192 KAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKL 227
Cdd:cd00555  144 KAGAYGIQGLGGALIERIEGDYSNVVGLPLPELLKL 179
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 32-231 5.62e-66

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 201.86  E-value: 5.62e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777   32 IILASGSPRRKQLFEQMGFPnVETCVSGFPEDLNKSmYITPWEYAADTSVQKAIAvyeklaaeedspdIVVSADTILILd 111
Cdd:pfam02545   1 LILASASPRRRELLEQLGIE-FEVVPSDIDETPLKE-DPAPEEYVLRLARAKAEA-------------LVIGADTVVVL- 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  112 seIMEKPNDPKHHLAMLKKLRNSKtpHKVFTAVSVIVPMEVPIHpgyvmKTHLEETQVKFDPsITDEFLEAYVRCGEGSD 191
Cdd:pfam02545  65 --ILGKPKDEEEARAMLKRLSGRT--HEVYTGVALINPGGGTGG-----VSFVETTRVTFRP-LSDEEIEAYVATGEPLD 134

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 429243777  192 KAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKLMEEA 231
Cdd:pfam02545 135 KAGAYGIQGLGAALVERIEGDYSNVVGLPLIELLRLLREL 174
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 30-231 4.92e-65

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 199.88  E-value: 4.92e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  30 KRIILASGSPRRKQLFEQMGFPnVETCVSGFPEDLNKSMyiTPWEYAADTSVQKAIAVYEKLAaeedsPDIVVSADTILI 109
Cdd:COG0424    1 PKLILASASPRRRELLEQLGLP-FEVVPPDIDETPLPGE--SPEELVLRLARAKAEAVAARLP-----DALVLGADTVVV 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 110 LDSEIMEKPNDPKHHLAMLKKLRNSKtpHKVFTAVSVIvpmevpiHPGYVMKTHLEETQVKFDPsITDEFLEAYVRCGEG 189
Cdd:COG0424   73 LDGRILGKPADAEEARAMLRRLSGRT--HRVHTGVALI-------DPGGRLWTRVVTTRVTFRP-LSDAEIEAYLATGEP 142

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 429243777 190 SDKAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKLMEEA 231
Cdd:COG0424  143 LDKAGAYGIQGLGAALVERIEGSYSNVVGLPLIELLELLREL 184
PRK00648 PRK00648
Maf-like protein; Reviewed
 28-230 8.59e-48

Maf-like protein; Reviewed


Pssm-ID: 234807  Cd Length: 191  Bit Score: 156.22  E-value: 8.59e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  28 KDKRIILASGSPRRKQLFEQMGFPNveTCVSGFPEDLNKSMYITPWEYAADTSVQKAIAVYEKLAAEEdspdIVVSADTI 107
Cdd:PRK00648   1 MKYKIILASSSPRRKEILEGFRIPF--EVVPSPFVEESYPYSLDPEEITLELARLKAEAVRSDLFPDE----LIITADTI 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 108 LILDSEIMEKPNDPKHHLAMLKKLRNsKTpHKVFTAVSVIvpmevpiHPGYVMKTHlEETQVKFDPsITDEFLEAYVRCG 187
Cdd:PRK00648  75 VWYDGKVLGKPKDEEEAVEMLRTLSG-KT-HEVITGVCLL-------HNGKLLSGS-ETTQVTFRE-LSDEEIEYYIDTY 143

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 429243777 188 EGSDKAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKLMEE 230
Cdd:PRK00648 144 KPLDKAGAYGIQEWGGLIVKKIEGSYYNVMGLPIQTLYEELKE 186
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 30-228 1.15e-47

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 155.63  E-value: 1.15e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777   30 KRIILASGSPRRKQLFEQMGFPnVETCVSGFPEDLNKSMyiTPWEYAADTSVQKAIAVYEKLaaeedsPD-IVVSADTIL 108
Cdd:TIGR00172   3 KELILASQSPRRKELLEELGIS-FEQIVSEFDEKSLKTT--SPRELVYRLAKEKAQAVAELL------ADaLIIGADTVV 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  109 ILDSEIMEKPNDPKHHLAMLKKLRNSKtpHKVFTAVSVIVPmevpihpgYVMKTHLEETQVKFDpSITDEFLEAYVRCGE 188
Cdd:TIGR00172  74 ILDGEIYGKPKDKEEAAEFLRKLSGQE--HEVYTAVALIDS--------VHLLTFLDVTKVHFR-ALDPEEIEKYVESGE 142

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 429243777  189 GSDKAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKLM 228
Cdd:TIGR00172 143 PLEKAGAFGIEGFGAPLIKKIDGDYSNVVGLPLEKLLGAL 182
PRK14361 PRK14361
Maf-like protein; Provisional
 32-231 3.00e-38

Maf-like protein; Provisional


Pssm-ID: 172837  Cd Length: 187  Bit Score: 131.59  E-value: 3.00e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  32 IILASGSPRRKQLFEQMGFPnVETCVSGFPEDlnkSMYITPWEYAADTSVQKAIAVyeklaAEEDSPDIVVSADTILILD 111
Cdd:PRK14361   1 VILASGSPRRRELLENLGVP-FQVVVSGEAED---STETDPARLAAELALLKARAV-----ARLHPDAVVIAADTVVALG 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 112 SEIMEKPNDPKHHLAMLKKLrnSKTPHKVFTAVSVIvpmevpiHPGyVMKTHLEETQVKFDPsITDEFLEAYVRCGEGSD 191
Cdd:PRK14361  72 GVLLAKPADEAENEAFLRVL--SGRTHQVYTGVAVL-------SRG-TEQVGVERTDVTFRA-LTAAEISFYARSGEGLD 140

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 429243777 192 KAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKLMEEA 231
Cdd:PRK14361 141 KAGGYGIQGVGMALVSRVEGDYSNVVGFPLSLVIRLLRGA 180
PRK14362 PRK14362
Maf-like protein; Provisional
 29-235 5.38e-38

Maf-like protein; Provisional


Pssm-ID: 172838  Cd Length: 207  Bit Score: 131.52  E-value: 5.38e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  29 DKRIILASGSPRRKQLFEQMGFP-NVETCVSGFPEDLNKSMyitPWEYAADTSVQKAIAVYEKLAAEedspdIVVSADTI 107
Cdd:PRK14362  11 ACPVVLASGSPRRREFLEQMGLPfEVILPGAAEPSPIEGEQ---PEAYARRAAEAKARAVAADHAGR-----LVIAADTV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 108 LILDSEIMEKPNDPKHHLAMLKKLrnSKTPHKVFTAVSVIVPmevpihpGYVMKTHLEETQVKFDPSiTDEFLEAYVRCG 187
Cdd:PRK14362  83 VALDGMILGKPADRADALSMLRRL--AGRTHEVVSACCVVLP-------DGGREVFHAITRVTMWDW-PEAALAAYVATG 152

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 429243777 188 EGSDKAGGYAIQGHGALLIESIIGDFSNVVGLPIRatfKLMEEALEQG 235
Cdd:PRK14362 153 EPSDKAGAYGIQGIGAFLVRSIEGSWSNVVGLPVA---ELTALLLRRG 197
PRK00078 PRK00078
Maf-like protein; Reviewed
 30-231 1.06e-37

Maf-like protein; Reviewed


Pssm-ID: 234618  Cd Length: 192  Bit Score: 130.23  E-value: 1.06e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  30 KRIILASGSPRRKQLFEQMgFPNVETCVSGFPEDL---NKSMYitpwEYAADTSVQKAIAVYEKLaaeEDSPDIVVSADT 106
Cdd:PRK00078   1 MKIILASASERRQELLKRI-LEDFQVIVSDFDESSvpfKGNIE----SYVMNLAEGKARSVSKKL---DQESSIVIGCDT 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 107 ILILDSEIMEKPNDPKHHLAMLKKLrnSKTPHKVFTAVSVIVPMEVPIHPGYVMkthleeTQVKFDpSITDEFLEAYVRC 186
Cdd:PRK00078  73 IVAFNGKVLGKPKDEEDAFEMLKAL--SGNEHEVYSGIAILDTKSNKIIKDFVC------TEVKFS-KLTDRQIRKYINT 143

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 429243777 187 GEGSDKAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKLMEEA 231
Cdd:PRK00078 144 GEPMDKAGAYGIQGKGGVFVEEINGCYYNVVGLPLNKLYKMLEEM 188
PRK14365 PRK14365
Maf-like protein; Provisional
 30-231 2.61e-36

Maf-like protein; Provisional


Pssm-ID: 237690  Cd Length: 197  Bit Score: 126.86  E-value: 2.61e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  30 KRIILASGSPRRKQLFEQMGFPNVETCVSGFPEDLNKSMyiTPWEYAADTSVQKAIAVyeklAAEEDSpDIVVSADTILI 109
Cdd:PRK14365   2 RRIILASASPRRKELLKQLIGDNFLVYPSSYEEPPQPGL--DPEELLLKHSLEKARDV----AKHFDS-GIIISADTSVF 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 110 LDSEIMEKPNDPKHHLAMLKKLRNSKTphKVFTAVSVIvPMEVPIHpgyvmKTHLEETQVKFDpSITDEFLEAYVRCGEG 189
Cdd:PRK14365  75 CNGEVLGKPASPENAEEMLEKLSGRKF--LVITGLTVL-DLDSGKE-----ISEIESTDVWMT-ELSREQILAYVRTGEP 145

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 429243777 190 SDKAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKLMEEA 231
Cdd:PRK14365 146 LDKAGAFAIQGKGAVLVEKIEGDFFNVVGLPLFRLGKILEKL 187
Maf_Ham1 cd00985
Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum ...
 32-171 4.40e-32

Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard nucleotides, such as hypoxanthine/xanthine NTP, but not standard nucleotides.


Pssm-ID: 238485  Cd Length: 131  Bit Score: 113.75  E-value: 4.40e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  32 IILASGSPRRKQLFEQMGFPNVETCVSGFPEDLNKSmyiTPWEYAADTSVQKAIAVYEKLAaeedsPDIVVSADTILILD 111
Cdd:cd00985    1 LILASGSPRRLEELKQIGGIEFEVLPSDIDETGLKG---EPEDTVEELALLKARAVAERLP-----DAPVIADDTGLVVD 72

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 112 SEIMEKPNDPKHHLAMLKKLRNSKtpHKVFTAVSVivpmevpIHPGYVMKTHLEETQVKF 171
Cdd:cd00985   73 GRPGGKPARFAEALEMLRGLSGRT--AEFVTAVAL-------VDPDGKIITFEGETEGKI 123
PRK14363 PRK14363
Maf-like protein; Provisional
 31-221 2.61e-31

Maf-like protein; Provisional


Pssm-ID: 184647  Cd Length: 204  Bit Score: 114.22  E-value: 2.61e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  31 RIILASGSPRRKQLFEQMGF------PNVETCVSGFPEDLNKSMyitpweyaadtSVQKAIAVYEKLAAEEDspdIVVSA 104
Cdd:PRK14363   2 RIILASSSPRRRQLMELLGIefevekPDVEEEFLESPEETVREL-----------SLRKAEWVFKKRKEEEI---LVIGS 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 105 DTILILDSEIMEKPNDPKHHLAMLKKLRNSKtpHKVFTAVSVIVPMEVpihpgyvmKTHLEETQVKFDpSITDEFLEAYV 184
Cdd:PRK14363  68 DTVVVLDGNILGKPESLEEAKGMLKKLSGRW--HVVYTGVAFVSSETK--------DVIVSSTKVRFR-ELPESVIDYYV 136

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 429243777 185 RCGEGSDKAGGYAIQGHGALLIESIIGDFSNVVGLPI 221
Cdd:PRK14363 137 EKYRPLDKAGAYGIQDFAAVFVEKIEGDFFTVVGFPL 173
PRK14368 PRK14368
Maf-like protein; Provisional
 28-221 1.02e-29

Maf-like protein; Provisional


Pssm-ID: 237693  Cd Length: 193  Bit Score: 109.87  E-value: 1.02e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  28 KDKRIILASGSPRRKQLFEQMGFpNVETCVSGFPEDLNKSMyiTPWEYAADTSVQKAIAVYEKLAAEedspdIVVSADTI 107
Cdd:PRK14368   3 ANSPIVLASASPRRSELLASAGI-EFDVVPADIPEEPLPGE--EPVDHVLRLAREKARAAAALAEGR-----FFIGADTI 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 108 LILDSEIMEKPNDPKHHLAMLKKLrnSKTPHKVFTAVSVIVpmevpiHPGYVMKTHLEETQVKFDPsITDEFLEAYVRCG 187
Cdd:PRK14368  75 VVCDGEIMGKPKDEADAVRMLKKL--SGVPHEVITGFAVYD------RERDGCVTKAVRTKVFFKP-LRDEEIRDYIATG 145

                        170       180       190
                 ....*....|....*....|....*....|....
gi 429243777 188 EGSDKAGGYAIQGHGALLIESIIGDFSNVVGLPI 221
Cdd:PRK14368 146 CPMDKAGAYAIQGGAAHMVRKIDGSYTNVVGLPL 179
PRK04694 PRK04694
Maf-like protein; Reviewed
 34-228 9.23e-26

Maf-like protein; Reviewed


Pssm-ID: 179873  Cd Length: 190  Bit Score: 99.27  E-value: 9.23e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  34 LASGSPRRKQLFEQMGFPnVETCVSGFPEdlNKSMYITPWEYAADTSVQKAIAVYEKLAAEeDSPDIVVSADTILILDSE 113
Cdd:PRK04694   4 LASRSPRRRELLQRLDVP-FQTLQLDVPE--VRAADESPDHYVQRVALEKAHAGLALVQAA-DADAIVLGSDTEVVLGER 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 114 IMEKPNDPKHHLAMLKKLrnSKTPHKVFTAVSVIVPMEVPIHPGYVmkthleeTQVKFDpSITDEFLEAYVRCGEGSDKA 193
Cdd:PRK04694  80 VFGKPVDVDDAIAMLRAL--SGRTHQVLTAVVLVCAQRAPAQALVV-------SEVTFD-LLDDAQIAAYAASGEPMGKA 149

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 429243777 194 GGYAIQGHGALLIESIIGDFSNVVGLPIRATFKLM 228
Cdd:PRK04694 150 GAYAIQGRAERFIRHLSGSYSGVMGLPLYQTSQLL 184
PRK14364 PRK14364
Maf-like protein; Provisional
 34-229 3.71e-25

Maf-like protein; Provisional


Pssm-ID: 184648  Cd Length: 181  Bit Score: 97.77  E-value: 3.71e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  34 LASGSPRRKQLFEQMGFpNVETcvsgFPEDLNKSMYI--TPWEYAADTSVQKAIAVYEKLaaeedsPD-IVVSADTILIL 110
Cdd:PRK14364   1 LASSSPRRRELLQQLGL-NFEI----YSPDIDESVHEgeLVHQYVERLAREKAQAVLNIF------PDsVIIAADTSLGL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 111 DSEIMEKPNDPKHHLAMLKKLrnSKTPHKVFTAVSVIVPMEvpihpgyvMKTHLEETQVKFDPsITDEFLEAYVRCGEGS 190
Cdd:PRK14364  70 DGQIIGKPDSKQHAFDIWKQL--SGRWHDVFSGICIATQQQ--------ILSQVVQTQVEFAS-LTTQDMEDYWATGEPV 138

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 429243777 191 DKAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKLME 229
Cdd:PRK14364 139 GKAGAYAIQGIASQYIPKIQGSYSNVVGLPLYEFSQLFK 177
PRK14367 PRK14367
Maf-like protein; Provisional
 32-230 4.53e-25

Maf-like protein; Provisional


Pssm-ID: 237692  Cd Length: 202  Bit Score: 97.83  E-value: 4.53e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  32 IILASGSPRRKQLFEQMGFPNVEtcvsgFPEDLNKSMYI--TPWEYA---ADTSVQKAIAVY-EKLAAEEDSPdiVVSAD 105
Cdd:PRK14367   4 LYLGSNSPRRMEILTQLGYRVVK-----LPAGIDETVKAgeTPARYVqrmAEEKNRTALTLFcETNGTMPDFP--LITAD 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 106 TILILDSEIMEKPNDPKHHLAMLKKLrnSKTPHKVFTAVSvivpmevpIHPGYVMKTHLEETQVKFDPsITDEFLEAYVR 185
Cdd:PRK14367  77 TCVVSDGIILGKPRSQAEAIEFLNRL--SGKQHTVLTAVC--------IHYRGKTSSRVQTNRVVFKP-LSSEEISAYVQ 145

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 429243777 186 CGEGSDKAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKLMEE 230
Cdd:PRK14367 146 SGEPMDKAGAYAVQGIGGIFIQSIEGSFSGIMGLPVYETVSMLQD 190
PRK01441 PRK01441
Maf-like protein; Reviewed
 30-228 1.20e-23

Maf-like protein; Reviewed


Pssm-ID: 167232  Cd Length: 207  Bit Score: 94.40  E-value: 1.20e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  30 KRIILASGSPRRKQLFEQMGF-PNvetcvSGFPEDLNKSMYIT--PWEYAADTSVQKAIAVYEKLAAEED-SPDIVVSAD 105
Cdd:PRK01441   5 PKLVLASGSPRRVELLNQAGIePD-----RLMPADIDETPKRAehPRSLARRLSREKAEAALEALQGDDDwRGAYILAAD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 106 TILILDSEIMEKPNDPKHHLAMLKKLrnSKTPHKVFTAVSVIVPMEVpihpgyvMKTHLEETQVKFDpSITDEFLEAYVR 185
Cdd:PRK01441  80 TVVAVGRRILPKAELVDEASQCLRLL--SGRNHRVYTGVCLVTPDGK-------LRQKLVETRVRFK-RLSREDIEAYLA 149

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 429243777 186 CGEGSDKAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKLM 228
Cdd:PRK01441 150 SGEWRGKAGGYAIQGIAGSFVVKLVGSYTNVVGLPLYETVSLL 192
PRK14366 PRK14366
Maf-like protein; Provisional
 26-228 2.96e-16

Maf-like protein; Provisional


Pssm-ID: 237691  Cd Length: 195  Bit Score: 74.45  E-value: 2.96e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  26 QLKDKRIILASGSPRRKQLFEQMGFPNVETcvsgFPEDLNKSmyITPWEYAADTSVQKAIAVYEKLAAEedSPD-IVVSA 104
Cdd:PRK14366   1 MLKFDNLILASSSKQRLALLEQIGVVPGEI----VSPDIDES--PLKKELPKDYSIRMAKEKAEKVQSL--RPDkFVLGA 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 105 DTILILDSEIMEKPNDPKHHLAMLKKLrnSKTPHKVFTAVSVIVPMEVpIHPGYVMkthleeTQVKFDpSITDEFLEAYV 184
Cdd:PRK14366  73 DTVVCCGRRILLKAETEEQAEEYLELL--SGRRHRVYTSVCLYTPGGK-LHIRSVV------TVVKFK-RLSKQEIKYYI 142

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 429243777 185 RCGEGSDKAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKLM 228
Cdd:PRK14366 143 ASGEWKGKAGGCNIQGLAGKFVLSINGSYSSIIGLPLHETYCLL 186
PRK02478 PRK02478
Maf-like protein; Reviewed
 32-238 1.57e-11

Maf-like protein; Reviewed


Pssm-ID: 167380  Cd Length: 199  Bit Score: 61.29  E-value: 1.57e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  32 IILASGSPRRKQLFEQMGFPnvetcVSGFPEDLNKSMYITPWEYAADTSVQKAIAVYEKLAAE--EDSPD-IVVSADTIL 108
Cdd:PRK02478   5 LILASKSPFRRALLENAGLE-----FSAAAADIDERAVEAPLEESGATPEDVALVLAEAKAIDvsERFPGaLVIGCDQTM 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 109 ILDSEIMEKPNDPKHHLAMLKKLrnSKTPHKVFTAVsvivpmeVPIHPGYVMKTHLEETQVKFDPsITDEFLEAYV-RCG 187
Cdd:PRK02478  80 SLGDEVFHKPKDMEEARRHLQKL--SGKTHQLNSAV-------VLVRDGKVLWRHVSIAHMTMRD-LDAGFIGRHLaRVG 149

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 429243777 188 EgsdKA----GGYAIQGHGALLIESIIGDFSNVVGLPIratFKLMEEALEQGDAD 238
Cdd:PRK02478 150 E---KAlssvGAYQLEGEGIQLFEKIEGDYFTILGLPL---LPLLAKLRELGAID 198
PRK04056 PRK04056
septum formation inhibitor Maf;
32-221 1.97e-09

septum formation inhibitor Maf;


Pssm-ID: 179732  Cd Length: 180  Bit Score: 55.35  E-value: 1.97e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777  32 IILASGSPRRKQL-------FEQMGFpnvetcvsGFPEDLNKSmyITPWEYAADTSVQKAIAVYEKLAAEEDspdiVVSA 104
Cdd:PRK04056   2 IILASSSSTRANLlkeagieFEQKSL--------DFDEESIKK--TSPKEFVYLAVKGKLEQFLKKYGNECN----LLVA 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429243777 105 DTILILDSEIMEKPNDPKHHLAMLKKLRNSKTphKVFTAVSVIVP-MEVpihpgyvmkTHLEETQVKFDPSITDEfLEAY 183
Cdd:PRK04056  68 DSVVSCGNKILRKAKDKEEAREMLKLQSGNEI--SVLTCMILKSPeKEW---------LDLSVTTYRFKKFDEDD-LEKY 135

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 429243777 184 VRCGEGSDKAGGYAIQGHGALLIESIIGDFSNVVGLPI 221
Cdd:PRK04056 136 LESGLWQGKAGACMVEGFHKKYIKSVSGNESTAMGLNV 173
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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