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Conserved domains on  [gi|19112180|ref|NP_595388|]
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Swr1 complex histone chaperone module subunit Swc2 [Schizosaccharomyces pombe]

Protein Classification

Vps72/YL1 family protein( domain architecture ID 12065836)

Vps72/YL1 family protein similar to budding yeast Vps72 (vacuolar protein sorting-associated protein 72), a Htz1-binding component of the SWR1 complex, which is required for the incorporation of the histone variant H2AZ into chromatin; contains YL1 C-terminal domain which is found in proteins that are not YL1 protein

Gene Ontology:  GO:0006355|GO:0006338|GO:0140849

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YL1 pfam05764
YL1 nuclear protein; The proteins in this family are designated YL1. These proteins have been ...
 11-231 1.31e-19

YL1 nuclear protein; The proteins in this family are designated YL1. These proteins have been shown to be DNA-binding and may be a transcription factor.


:

Pssm-ID: 461734 [Multi-domain]  Cd Length: 245  Bit Score: 85.93  E-value: 1.31e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112180    11 RTRRANAGNKMRELLEKEHlrmtqQNAEIEKEDEEY------NIEEEEEAERDIEISSESSDEEAELKKLEEEGEEVEKI 84
Cdd:pfam05764   1 RARRSTAGNRMKKLLEQEL-----EDDELELLFAEEeddeefESEEEEEDESDSDFDSSEDDEDSEEEEDDDEGEKELQR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112180    85 LRDEERIKKRKIQKNRAANLQRTLQPPKRPTPSAASEVPKKKYKKIK--------------VDPSARRTSSRMHTVLMAQ 150
Cdd:pfam05764  76 QERKKRRSKKEKKKRKAQEAILKLFKKAAIKRKKVKIDKPRKAPAPRpkkkseraswlpteEDGPTRRKSSRSSTVQNKE 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112180   151 STETRLQEAKPRR--------KYTVSASANRQKGTMTQQQRFEEAAKTEAQNLSSLRNYVHLEEQRR-LRLKRNAAKHRQ 221
Cdd:pfam05764 156 ATHERLKEAEERRkkqlarmkKKAARKKKKKEEKPLTQEERLAEAAETEEINLKSLNRWEEQEEEKKkEQRAKLAALKRR 235

                         250
                  ....*....|
gi 19112180   222 LREPILKFIS 231
Cdd:pfam05764 236 KLGPVIRYWS 245
YL1_C smart00993
YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. ...
 271-298 4.51e-10

YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. These proteins have been shown to be DNA-binding and may be a transcription factor. This domain is found in proteins that are not YL1 proteins.


:

Pssm-ID: 198061 [Multi-domain]  Cd Length: 30  Bit Score: 54.05  E-value: 4.51e-10
                           10        20
                   ....*....|....*....|....*...
gi 19112180    271 CVITGKPAIYLDPVTQLPISNVQAFQQV 298
Cdd:smart00993   3 CDITGLPARYRDPKTGLRYANAEAYKVI 30
 
Name Accession Description Interval E-value
YL1 pfam05764
YL1 nuclear protein; The proteins in this family are designated YL1. These proteins have been ...
 11-231 1.31e-19

YL1 nuclear protein; The proteins in this family are designated YL1. These proteins have been shown to be DNA-binding and may be a transcription factor.


Pssm-ID: 461734 [Multi-domain]  Cd Length: 245  Bit Score: 85.93  E-value: 1.31e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112180    11 RTRRANAGNKMRELLEKEHlrmtqQNAEIEKEDEEY------NIEEEEEAERDIEISSESSDEEAELKKLEEEGEEVEKI 84
Cdd:pfam05764   1 RARRSTAGNRMKKLLEQEL-----EDDELELLFAEEeddeefESEEEEEDESDSDFDSSEDDEDSEEEEDDDEGEKELQR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112180    85 LRDEERIKKRKIQKNRAANLQRTLQPPKRPTPSAASEVPKKKYKKIK--------------VDPSARRTSSRMHTVLMAQ 150
Cdd:pfam05764  76 QERKKRRSKKEKKKRKAQEAILKLFKKAAIKRKKVKIDKPRKAPAPRpkkkseraswlpteEDGPTRRKSSRSSTVQNKE 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112180   151 STETRLQEAKPRR--------KYTVSASANRQKGTMTQQQRFEEAAKTEAQNLSSLRNYVHLEEQRR-LRLKRNAAKHRQ 221
Cdd:pfam05764 156 ATHERLKEAEERRkkqlarmkKKAARKKKKKEEKPLTQEERLAEAAETEEINLKSLNRWEEQEEEKKkEQRAKLAALKRR 235

                         250
                  ....*....|
gi 19112180   222 LREPILKFIS 231
Cdd:pfam05764 236 KLGPVIRYWS 245
YL1_C smart00993
YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. ...
 271-298 4.51e-10

YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. These proteins have been shown to be DNA-binding and may be a transcription factor. This domain is found in proteins that are not YL1 proteins.


Pssm-ID: 198061 [Multi-domain]  Cd Length: 30  Bit Score: 54.05  E-value: 4.51e-10
                           10        20
                   ....*....|....*....|....*...
gi 19112180    271 CVITGKPAIYLDPVTQLPISNVQAFQQV 298
Cdd:smart00993   3 CDITGLPARYRDPKTGLRYANAEAYKVI 30
YL1_C pfam08265
YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. ...
 271-298 2.12e-09

YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. These proteins have been shown to be DNA-binding and may be a transcription factor. This domain is found in proteins that are not YL1 proteins.


Pssm-ID: 462412  Cd Length: 29  Bit Score: 51.98  E-value: 2.12e-09
                          10        20
                  ....*....|....*....|....*...
gi 19112180   271 CVITGKPAIYLDPVTQLPISNVQAFQQV 298
Cdd:pfam08265   2 CDITGLPAKYRDPKTGLPYANVEAYKVI 29
 
Name Accession Description Interval E-value
YL1 pfam05764
YL1 nuclear protein; The proteins in this family are designated YL1. These proteins have been ...
 11-231 1.31e-19

YL1 nuclear protein; The proteins in this family are designated YL1. These proteins have been shown to be DNA-binding and may be a transcription factor.


Pssm-ID: 461734 [Multi-domain]  Cd Length: 245  Bit Score: 85.93  E-value: 1.31e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112180    11 RTRRANAGNKMRELLEKEHlrmtqQNAEIEKEDEEY------NIEEEEEAERDIEISSESSDEEAELKKLEEEGEEVEKI 84
Cdd:pfam05764   1 RARRSTAGNRMKKLLEQEL-----EDDELELLFAEEeddeefESEEEEEDESDSDFDSSEDDEDSEEEEDDDEGEKELQR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112180    85 LRDEERIKKRKIQKNRAANLQRTLQPPKRPTPSAASEVPKKKYKKIK--------------VDPSARRTSSRMHTVLMAQ 150
Cdd:pfam05764  76 QERKKRRSKKEKKKRKAQEAILKLFKKAAIKRKKVKIDKPRKAPAPRpkkkseraswlpteEDGPTRRKSSRSSTVQNKE 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112180   151 STETRLQEAKPRR--------KYTVSASANRQKGTMTQQQRFEEAAKTEAQNLSSLRNYVHLEEQRR-LRLKRNAAKHRQ 221
Cdd:pfam05764 156 ATHERLKEAEERRkkqlarmkKKAARKKKKKEEKPLTQEERLAEAAETEEINLKSLNRWEEQEEEKKkEQRAKLAALKRR 235

                         250
                  ....*....|
gi 19112180   222 LREPILKFIS 231
Cdd:pfam05764 236 KLGPVIRYWS 245
YL1_C smart00993
YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. ...
 271-298 4.51e-10

YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. These proteins have been shown to be DNA-binding and may be a transcription factor. This domain is found in proteins that are not YL1 proteins.


Pssm-ID: 198061 [Multi-domain]  Cd Length: 30  Bit Score: 54.05  E-value: 4.51e-10
                           10        20
                   ....*....|....*....|....*...
gi 19112180    271 CVITGKPAIYLDPVTQLPISNVQAFQQV 298
Cdd:smart00993   3 CDITGLPARYRDPKTGLRYANAEAYKVI 30
YL1_C pfam08265
YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. ...
 271-298 2.12e-09

YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. These proteins have been shown to be DNA-binding and may be a transcription factor. This domain is found in proteins that are not YL1 proteins.


Pssm-ID: 462412  Cd Length: 29  Bit Score: 51.98  E-value: 2.12e-09
                          10        20
                  ....*....|....*....|....*...
gi 19112180   271 CVITGKPAIYLDPVTQLPISNVQAFQQV 298
Cdd:pfam08265   2 CDITGLPAKYRDPKTGLPYANVEAYKVI 29
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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