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Conserved domains on  [gi|63054719|ref|NP_595429|]
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dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase [Schizosaccharomyces pombe]

Protein Classification

glycosyltransferase family protein( domain architecture ID 229536)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PMT_2 super family cl21590
Dolichyl-phosphate-mannose-protein mannosyltransferase; This family contains members that are ...
 31-351 3.90e-24

Dolichyl-phosphate-mannose-protein mannosyltransferase; This family contains members that are not captured by pfam02366.


The actual alignment was detected with superfamily member pfam03901:

Pssm-ID: 473917  Cd Length: 414  Bit Score: 104.75  E-value: 3.90e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63054719    31 KVEESFAMQAIHDIQTYRWDLSKYDHLEFPGAvkRSFIPSLFIAVLSYIPSWFV-----NPLLAARWTIGYLSWESMNSV 105
Cdd:pfam03901  21 DPDEHFQSWEPLHYLIFGYGFLTWEWSPKYGI--RSYLYPLLFALPYYLLARLFgdskyLVFYAPRLLLGLFSALCDYYL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63054719   106 SCSISKRFGTLSGALFILFSCAQFHLVYYMSRPLSNIFGLIATNHSLSLLLKN--------NYYGSISILVFAAAIVRSE 177
Cdd:pfam03901  99 YRAVCRKYGLEIARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLLEYgntsvsnyKYLKAVLLIAALAILGRPT 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63054719   178 IALLLMCLILPLLLQRRITLSKLLL-----VGISSSLAAVGASFLIDSYFWGAWCWPELEAFLFNVVEGKSSDWGTSPFY 252
Cdd:pfam03901 179 SALLWLPLVLYLLLRLRGKRLKLFLflaisLGLLVALLVLGAVILIDSYFYGRFVFTPLNFLKYNVLSNGSSFYGTHPWY 258

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63054719   253 YYFVRLPWLFLNPTTLLFLLISFVYIKPAR----LLIYVPLFFIFVYSFLGHKEWRFIIYSIPWFNAASAIGASLCFNAS 328
Cdd:pfam03901 259 FYFSNGLPNILGPFLLAFILGPLVLLLRKVsrlsQLLAPILIWLFIYSLQPHKEERFLYPVYPLILLSAAIALTRLSRRS 338

                         330       340
                  ....*....|....*....|...
gi 63054719   329 KFGKKIFEILRLMFFSGIIFGFI 351
Cdd:pfam03901 339 WKVRKKLSLLFLLLFFNVSLARL 361
 
Name Accession Description Interval E-value
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
 31-351 3.90e-24

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 104.75  E-value: 3.90e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63054719    31 KVEESFAMQAIHDIQTYRWDLSKYDHLEFPGAvkRSFIPSLFIAVLSYIPSWFV-----NPLLAARWTIGYLSWESMNSV 105
Cdd:pfam03901  21 DPDEHFQSWEPLHYLIFGYGFLTWEWSPKYGI--RSYLYPLLFALPYYLLARLFgdskyLVFYAPRLLLGLFSALCDYYL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63054719   106 SCSISKRFGTLSGALFILFSCAQFHLVYYMSRPLSNIFGLIATNHSLSLLLKN--------NYYGSISILVFAAAIVRSE 177
Cdd:pfam03901  99 YRAVCRKYGLEIARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLLEYgntsvsnyKYLKAVLLIAALAILGRPT 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63054719   178 IALLLMCLILPLLLQRRITLSKLLL-----VGISSSLAAVGASFLIDSYFWGAWCWPELEAFLFNVVEGKSSDWGTSPFY 252
Cdd:pfam03901 179 SALLWLPLVLYLLLRLRGKRLKLFLflaisLGLLVALLVLGAVILIDSYFYGRFVFTPLNFLKYNVLSNGSSFYGTHPWY 258

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63054719   253 YYFVRLPWLFLNPTTLLFLLISFVYIKPAR----LLIYVPLFFIFVYSFLGHKEWRFIIYSIPWFNAASAIGASLCFNAS 328
Cdd:pfam03901 259 FYFSNGLPNILGPFLLAFILGPLVLLLRKVsrlsQLLAPILIWLFIYSLQPHKEERFLYPVYPLILLSAAIALTRLSRRS 338

                         330       340
                  ....*....|....*....|...
gi 63054719   329 KFGKKIFEILRLMFFSGIIFGFI 351
Cdd:pfam03901 339 WKVRKKLSLLFLLLFFNVSLARL 361
PLN02816 PLN02816
mannosyltransferase
 212-311 2.28e-04

mannosyltransferase


Pssm-ID: 215437  Cd Length: 546  Bit Score: 43.87  E-value: 2.28e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63054719  212 VGASFLIDSYFWGAWCWPELEAFLFNVVEGKSSDWGTSPFYYYFVRlPWLFLNPTTLLFLLISFVYIKPARLLIYVpLFF 291
Cdd:PLN02816 251 LGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQ-GFLVMLFTFTPFSIAGIIKSKNQKLSALI-LWV 328

                         90       100
                 ....*....|....*....|
gi 63054719  292 IFVYSFLGHKEWRFIIYSIP 311
Cdd:PLN02816 329 LAIYSILGHKEFRFVLPVLP 348
 
Name Accession Description Interval E-value
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
 31-351 3.90e-24

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 104.75  E-value: 3.90e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63054719    31 KVEESFAMQAIHDIQTYRWDLSKYDHLEFPGAvkRSFIPSLFIAVLSYIPSWFV-----NPLLAARWTIGYLSWESMNSV 105
Cdd:pfam03901  21 DPDEHFQSWEPLHYLIFGYGFLTWEWSPKYGI--RSYLYPLLFALPYYLLARLFgdskyLVFYAPRLLLGLFSALCDYYL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63054719   106 SCSISKRFGTLSGALFILFSCAQFHLVYYMSRPLSNIFGLIATNHSLSLLLKN--------NYYGSISILVFAAAIVRSE 177
Cdd:pfam03901  99 YRAVCRKYGLEIARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLLEYgntsvsnyKYLKAVLLIAALAILGRPT 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63054719   178 IALLLMCLILPLLLQRRITLSKLLL-----VGISSSLAAVGASFLIDSYFWGAWCWPELEAFLFNVVEGKSSDWGTSPFY 252
Cdd:pfam03901 179 SALLWLPLVLYLLLRLRGKRLKLFLflaisLGLLVALLVLGAVILIDSYFYGRFVFTPLNFLKYNVLSNGSSFYGTHPWY 258

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63054719   253 YYFVRLPWLFLNPTTLLFLLISFVYIKPAR----LLIYVPLFFIFVYSFLGHKEWRFIIYSIPWFNAASAIGASLCFNAS 328
Cdd:pfam03901 259 FYFSNGLPNILGPFLLAFILGPLVLLLRKVsrlsQLLAPILIWLFIYSLQPHKEERFLYPVYPLILLSAAIALTRLSRRS 338

                         330       340
                  ....*....|....*....|...
gi 63054719   329 KFGKKIFEILRLMFFSGIIFGFI 351
Cdd:pfam03901 339 WKVRKKLSLLFLLLFFNVSLARL 361
PLN02816 PLN02816
mannosyltransferase
 212-311 2.28e-04

mannosyltransferase


Pssm-ID: 215437  Cd Length: 546  Bit Score: 43.87  E-value: 2.28e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63054719  212 VGASFLIDSYFWGAWCWPELEAFLFNVVEGKSSDWGTSPFYYYFVRlPWLFLNPTTLLFLLISFVYIKPARLLIYVpLFF 291
Cdd:PLN02816 251 LGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQ-GFLVMLFTFTPFSIAGIIKSKNQKLSALI-LWV 328

                         90       100
                 ....*....|....*....|
gi 63054719  292 IFVYSFLGHKEWRFIIYSIP 311
Cdd:PLN02816 329 LAIYSILGHKEFRFVLPVLP 348
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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