Swr1 complex histone chaperone module subunit Vps71 [Schizosaccharomyces pombe]
Protein Classification
zinc finger HIT domain-containing protein( domain architecture ID 19137923)
zinc finger HIT domain-containing protein may be involved in Box C/D snoRNP Biogenesis
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| zf-HIT_ZNHIT1_like | cd21437 | HIT zinc finger found in zinc finger HIT domain-containing protein 1 (ZNHIT1) and similar ... |
93-135 | 4.41e-20 | ||
HIT zinc finger found in zinc finger HIT domain-containing protein 1 (ZNHIT1) and similar proteins; The family includes ZNHIT1 and its yeast counterpart, the vacuolar protein sorting-associated protein 71 (Vps71p). ZNHIT1, also known as cyclin-G1-binding protein 1 (CGBP1), zinc finger protein subfamily 4A member 1 (ZNFN4A1), or p18 Hamlet, may have a role in inducing apoptosis through p53 signaling. It binds to Rev-erb beta and releases its inhibitory effect on the transcription of apolipoprotein C3 (APOC3) without affecting its DNA-binding activity. The yeast counterpart Vps71p, also referred to as SWR complex protein 6 (Swc6p), plays a role in the exchange of histone H2A for the H2A variant HZT1, a euchromatin-specific factor, leading to chromatin remodeling and transcriptional changes of targeted genes. It is indirectly involved in vacuolar protein sorting. Members of this family contain a zf-HIT domain characterized by a "treble-clef" fold through interleaved CCCC and CCHC zinc finger motifs, both of which bind a zinc ion. : Pssm-ID: 467791 Cd Length: 43 Bit Score: 77.27 E-value: 4.41e-20
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| Name | Accession | Description | Interval | E-value | ||
| zf-HIT_ZNHIT1_like | cd21437 | HIT zinc finger found in zinc finger HIT domain-containing protein 1 (ZNHIT1) and similar ... |
93-135 | 4.41e-20 | ||
HIT zinc finger found in zinc finger HIT domain-containing protein 1 (ZNHIT1) and similar proteins; The family includes ZNHIT1 and its yeast counterpart, the vacuolar protein sorting-associated protein 71 (Vps71p). ZNHIT1, also known as cyclin-G1-binding protein 1 (CGBP1), zinc finger protein subfamily 4A member 1 (ZNFN4A1), or p18 Hamlet, may have a role in inducing apoptosis through p53 signaling. It binds to Rev-erb beta and releases its inhibitory effect on the transcription of apolipoprotein C3 (APOC3) without affecting its DNA-binding activity. The yeast counterpart Vps71p, also referred to as SWR complex protein 6 (Swc6p), plays a role in the exchange of histone H2A for the H2A variant HZT1, a euchromatin-specific factor, leading to chromatin remodeling and transcriptional changes of targeted genes. It is indirectly involved in vacuolar protein sorting. Members of this family contain a zf-HIT domain characterized by a "treble-clef" fold through interleaved CCCC and CCHC zinc finger motifs, both of which bind a zinc ion. Pssm-ID: 467791 Cd Length: 43 Bit Score: 77.27 E-value: 4.41e-20
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| zf-HIT | pfam04438 | HIT zinc finger; This presumed zinc finger contains up to 6 cysteine residues that could ... |
98-125 | 1.45e-07 | ||
HIT zinc finger; This presumed zinc finger contains up to 6 cysteine residues that could coordinate zinc. The domain is named after the HIT protein. This domain is also found in the Thyroid receptor interacting protein 3 (TRIP-3) that specifically interact with the ligand binding domain of the thyroid receptor. Pssm-ID: 461310 Cd Length: 30 Bit Score: 44.93 E-value: 1.45e-07
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| Name | Accession | Description | Interval | E-value | ||
| zf-HIT_ZNHIT1_like | cd21437 | HIT zinc finger found in zinc finger HIT domain-containing protein 1 (ZNHIT1) and similar ... |
93-135 | 4.41e-20 | ||
HIT zinc finger found in zinc finger HIT domain-containing protein 1 (ZNHIT1) and similar proteins; The family includes ZNHIT1 and its yeast counterpart, the vacuolar protein sorting-associated protein 71 (Vps71p). ZNHIT1, also known as cyclin-G1-binding protein 1 (CGBP1), zinc finger protein subfamily 4A member 1 (ZNFN4A1), or p18 Hamlet, may have a role in inducing apoptosis through p53 signaling. It binds to Rev-erb beta and releases its inhibitory effect on the transcription of apolipoprotein C3 (APOC3) without affecting its DNA-binding activity. The yeast counterpart Vps71p, also referred to as SWR complex protein 6 (Swc6p), plays a role in the exchange of histone H2A for the H2A variant HZT1, a euchromatin-specific factor, leading to chromatin remodeling and transcriptional changes of targeted genes. It is indirectly involved in vacuolar protein sorting. Members of this family contain a zf-HIT domain characterized by a "treble-clef" fold through interleaved CCCC and CCHC zinc finger motifs, both of which bind a zinc ion. Pssm-ID: 467791 Cd Length: 43 Bit Score: 77.27 E-value: 4.41e-20
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| zf-HIT | pfam04438 | HIT zinc finger; This presumed zinc finger contains up to 6 cysteine residues that could ... |
98-125 | 1.45e-07 | ||
HIT zinc finger; This presumed zinc finger contains up to 6 cysteine residues that could coordinate zinc. The domain is named after the HIT protein. This domain is also found in the Thyroid receptor interacting protein 3 (TRIP-3) that specifically interact with the ligand binding domain of the thyroid receptor. Pssm-ID: 461310 Cd Length: 30 Bit Score: 44.93 E-value: 1.45e-07
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