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Conserved domains on  [gi|19113053|ref|NP_596261|]
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microtubule-anchoring factor Msd1 [Schizosaccharomyces pombe]

Protein Classification

ADIP domain-containing protein( domain architecture ID 11189566)

ADIP domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ADIP pfam11559
Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at ...
 14-161 2.74e-33

Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at cell-cell adherens junctions, and in Sch. pombe and other fungi where it anchors spindle-pole bodies to spindle microtubules. It is a coiled-coil structure, and in pombe, it is required for anchoring the minus end of spindle microtubules to the centrosome equivalent, the spindle-pole body. The name ADIP derives from the family being composed of Afadin- and alpha -Actinin-Binding Proteins localized at Cell-Cell Adherens Junctions.


:

Pssm-ID: 463295 [Multi-domain]  Cd Length: 151  Bit Score: 120.11  E-value: 2.74e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113053    14 EESLLYINKSLFSKGVIQAEKLRLSHD--IRDNCNIVNIIYRLLRATDEERLEKESLLDAIKNNEYEKQRDNNTIKRLKN 91
Cdd:pfam11559   1 ENAITYINQTLLSRGFLRSGLLFDTAEgvEENIARIINVIYELLQQRDRDLEFRESLNETIRTLEAEIERLQSKIERLKT 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113053    92 ELELYQNECQLQLNKVRTLERDQAELITQNKGLKDVNAKNELTLKALKNQLSVSLRQHEQQMETLKGNYG 161
Cdd:pfam11559  81 QLEDLERELALLQAKERQLEKKLKTLEQKLKNEKEELQRLKNALQQIKTQFAHEVKKRDREIEKLKERLA 150
 
Name Accession Description Interval E-value
ADIP pfam11559
Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at ...
 14-161 2.74e-33

Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at cell-cell adherens junctions, and in Sch. pombe and other fungi where it anchors spindle-pole bodies to spindle microtubules. It is a coiled-coil structure, and in pombe, it is required for anchoring the minus end of spindle microtubules to the centrosome equivalent, the spindle-pole body. The name ADIP derives from the family being composed of Afadin- and alpha -Actinin-Binding Proteins localized at Cell-Cell Adherens Junctions.


Pssm-ID: 463295 [Multi-domain]  Cd Length: 151  Bit Score: 120.11  E-value: 2.74e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113053    14 EESLLYINKSLFSKGVIQAEKLRLSHD--IRDNCNIVNIIYRLLRATDEERLEKESLLDAIKNNEYEKQRDNNTIKRLKN 91
Cdd:pfam11559   1 ENAITYINQTLLSRGFLRSGLLFDTAEgvEENIARIINVIYELLQQRDRDLEFRESLNETIRTLEAEIERLQSKIERLKT 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113053    92 ELELYQNECQLQLNKVRTLERDQAELITQNKGLKDVNAKNELTLKALKNQLSVSLRQHEQQMETLKGNYG 161
Cdd:pfam11559  81 QLEDLERELALLQAKERQLEKKLKTLEQKLKNEKEELQRLKNALQQIKTQFAHEVKKRDREIEKLKERLA 150
 
Name Accession Description Interval E-value
ADIP pfam11559
Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at ...
 14-161 2.74e-33

Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at cell-cell adherens junctions, and in Sch. pombe and other fungi where it anchors spindle-pole bodies to spindle microtubules. It is a coiled-coil structure, and in pombe, it is required for anchoring the minus end of spindle microtubules to the centrosome equivalent, the spindle-pole body. The name ADIP derives from the family being composed of Afadin- and alpha -Actinin-Binding Proteins localized at Cell-Cell Adherens Junctions.


Pssm-ID: 463295 [Multi-domain]  Cd Length: 151  Bit Score: 120.11  E-value: 2.74e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113053    14 EESLLYINKSLFSKGVIQAEKLRLSHD--IRDNCNIVNIIYRLLRATDEERLEKESLLDAIKNNEYEKQRDNNTIKRLKN 91
Cdd:pfam11559   1 ENAITYINQTLLSRGFLRSGLLFDTAEgvEENIARIINVIYELLQQRDRDLEFRESLNETIRTLEAEIERLQSKIERLKT 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113053    92 ELELYQNECQLQLNKVRTLERDQAELITQNKGLKDVNAKNELTLKALKNQLSVSLRQHEQQMETLKGNYG 161
Cdd:pfam11559  81 QLEDLERELALLQAKERQLEKKLKTLEQKLKNEKEELQRLKNALQQIKTQFAHEVKKRDREIEKLKERLA 150
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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