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Conserved domains on  [gi|19113269|ref|NP_596477|]
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Noc2p-Noc3p complex subunit Noc3 [Schizosaccharomyces pombe]

Protein Classification

nucleolar complex-associated protein 3( domain architecture ID 11473819)

nucleolar complex-associated protein 3 (NOC3) is required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm; also required for initiation of DNA replication

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
NOC3 COG5117
Protein involved in the nuclear export of pre-ribosomes [Translation, ribosomal structure and ...
25-747 0e+00

Protein involved in the nuclear export of pre-ribosomes [Translation, ribosomal structure and biogenesis / Intracellular trafficking and secretion];


:

Pssm-ID: 227447 [Multi-domain]  Cd Length: 657  Bit Score: 875.12  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269  25 SSKRNNSQSSTEPRknatsldskkTTKKgvalpeiAERELTQEDIEFFNENPsslkylssinpEDLGKKVekgprpdIYD 104
Cdd:COG5117   1 SSKRNNSQSSTEPR----------TTKK-------AERELTQEDIEFFNENP-----------EDLGKKV-------IYD 45
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 105 LKKSqqfeldtsrlSSDEEsvldyskdsedEQDYELRPRVSSSWNNESYNRLPIKTKDgllqNVVADVNNGEEFLSESES 184
Cdd:COG5117  46 LKKS----------SSDEE-----------EQDYELRPRVSSSWNNESYNRLPIKTKD----NVVADVNNGEEFLSESES 100
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 185 EASLEIDSDIKDEKQKSLEEQKIAPEIPVKQQIKNDKEALGIQAQQLLEEPVENLHLIRNIFEKFDSPYITIKKLSLLTL 264
Cdd:COG5117 101 EASLEIDSDIKDEKQKSLEEQKIAPEIPVKQQIDSEKERIASICTKIIEEPEENLGMMEEVFSMITSMAEKAKKVSYLSL 180
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 265 LAVFRDIIPGYKIRPLSEEEQGTKLSKEVAQRWEYEQTLLKHYAKFLQTLETILKSFSsTLDETQLSLYQVAVRCCTKLI 344
Cdd:COG5117 181 LKVFKAIIPGYKIRPLKEEEQMVKDSKEVLHLKDYEQSLLRWYTSYIKTLVDDVKDES-TLDETQSSLYQVAYISLCELI 259
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 345 EQASHFNLSEKLFALAVRQISHKTKRPGFDGIINSLKNIFEEDNLGKTSLKCVTILSRMFKQRNYDVLPDVYDLFLSVNI 424
Cdd:COG5117 260 QHASHFNCTDKVFSLVLRGILGTTKRPVSMLIIDTIKSKLEEDCTGKTSLVATVIDQMLDKERNPLVLEYVLDIPLSDNS 339
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 425 LNDMKIKDEAWQDDTTNFKKRKKDLPYLTKKARKNYKETKKITQEMKEADAVITAQDKEKYQSEILKIIFITYFKTLQLK 504
Cdd:COG5117 340 LRDEEKARKYWEANKPVSKREKKDIFHLSKKLRKIEKERLRIQSEMRDAEDIEEAIEEEKNQSEILKIIFRLYFMVLKGD 419
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 505 GK-LIGNALEGVARLSHLLNIEFLGDLLQVLRELVMDDtvflPKDKSGVQATREALLTVSTAFEIASAQGVGKLNLDLDl 583
Cdd:COG5117 420 RKdLIGYVLEGLVKYRKIINPEFLGDLLEVLYELLNDN----PLDKISSDARRQALLCILTAFEIASATLYGKENYDLG- 494
                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 584 gLFVQRLYKIIFPFSLNPDADLNLKIKRLKDPDAPSKPFVVNATTEMEMLLKCFQVFFFKSKNISSSRLSSFSKRLAIAS 663
Cdd:COG5117 495 -GFVDLLYSMVHPMNLEPDADLNLKIKRLKDPDAPSKPFVVNATTDNEELLKIVRLLFFKSKQPVHRRHVIFKKRLLYCC 573
                       650       660       670       680       690       700       710       720
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 664 MQLPEHSASADLALLKKLLSRYSKLSRLLTSEEQIGDGIYNPFIEDPDLSNSSTAVLYEPFLLKNHYSPAVSQSAKELLK 743
Cdd:COG5117 574 SRSPEEFKGAILDISAKLDIRYSDCSNLKCSEFDIGAGNVDSIPSNPDLSNSSTAVLFEYFLLKQHYSPAVSQSAKELLK 653

                ....
gi 19113269 744 STSL 747
Cdd:COG5117 654 STSL 657
 
Name Accession Description Interval E-value
NOC3 COG5117
Protein involved in the nuclear export of pre-ribosomes [Translation, ribosomal structure and ...
25-747 0e+00

Protein involved in the nuclear export of pre-ribosomes [Translation, ribosomal structure and biogenesis / Intracellular trafficking and secretion];


Pssm-ID: 227447 [Multi-domain]  Cd Length: 657  Bit Score: 875.12  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269  25 SSKRNNSQSSTEPRknatsldskkTTKKgvalpeiAERELTQEDIEFFNENPsslkylssinpEDLGKKVekgprpdIYD 104
Cdd:COG5117   1 SSKRNNSQSSTEPR----------TTKK-------AERELTQEDIEFFNENP-----------EDLGKKV-------IYD 45
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 105 LKKSqqfeldtsrlSSDEEsvldyskdsedEQDYELRPRVSSSWNNESYNRLPIKTKDgllqNVVADVNNGEEFLSESES 184
Cdd:COG5117  46 LKKS----------SSDEE-----------EQDYELRPRVSSSWNNESYNRLPIKTKD----NVVADVNNGEEFLSESES 100
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 185 EASLEIDSDIKDEKQKSLEEQKIAPEIPVKQQIKNDKEALGIQAQQLLEEPVENLHLIRNIFEKFDSPYITIKKLSLLTL 264
Cdd:COG5117 101 EASLEIDSDIKDEKQKSLEEQKIAPEIPVKQQIDSEKERIASICTKIIEEPEENLGMMEEVFSMITSMAEKAKKVSYLSL 180
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 265 LAVFRDIIPGYKIRPLSEEEQGTKLSKEVAQRWEYEQTLLKHYAKFLQTLETILKSFSsTLDETQLSLYQVAVRCCTKLI 344
Cdd:COG5117 181 LKVFKAIIPGYKIRPLKEEEQMVKDSKEVLHLKDYEQSLLRWYTSYIKTLVDDVKDES-TLDETQSSLYQVAYISLCELI 259
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 345 EQASHFNLSEKLFALAVRQISHKTKRPGFDGIINSLKNIFEEDNLGKTSLKCVTILSRMFKQRNYDVLPDVYDLFLSVNI 424
Cdd:COG5117 260 QHASHFNCTDKVFSLVLRGILGTTKRPVSMLIIDTIKSKLEEDCTGKTSLVATVIDQMLDKERNPLVLEYVLDIPLSDNS 339
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 425 LNDMKIKDEAWQDDTTNFKKRKKDLPYLTKKARKNYKETKKITQEMKEADAVITAQDKEKYQSEILKIIFITYFKTLQLK 504
Cdd:COG5117 340 LRDEEKARKYWEANKPVSKREKKDIFHLSKKLRKIEKERLRIQSEMRDAEDIEEAIEEEKNQSEILKIIFRLYFMVLKGD 419
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 505 GK-LIGNALEGVARLSHLLNIEFLGDLLQVLRELVMDDtvflPKDKSGVQATREALLTVSTAFEIASAQGVGKLNLDLDl 583
Cdd:COG5117 420 RKdLIGYVLEGLVKYRKIINPEFLGDLLEVLYELLNDN----PLDKISSDARRQALLCILTAFEIASATLYGKENYDLG- 494
                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 584 gLFVQRLYKIIFPFSLNPDADLNLKIKRLKDPDAPSKPFVVNATTEMEMLLKCFQVFFFKSKNISSSRLSSFSKRLAIAS 663
Cdd:COG5117 495 -GFVDLLYSMVHPMNLEPDADLNLKIKRLKDPDAPSKPFVVNATTDNEELLKIVRLLFFKSKQPVHRRHVIFKKRLLYCC 573
                       650       660       670       680       690       700       710       720
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 664 MQLPEHSASADLALLKKLLSRYSKLSRLLTSEEQIGDGIYNPFIEDPDLSNSSTAVLYEPFLLKNHYSPAVSQSAKELLK 743
Cdd:COG5117 574 SRSPEEFKGAILDISAKLDIRYSDCSNLKCSEFDIGAGNVDSIPSNPDLSNSSTAVLFEYFLLKQHYSPAVSQSAKELLK 653

                ....
gi 19113269 744 STSL 747
Cdd:COG5117 654 STSL 657
NOC3p pfam07540
Nucleolar complex-associated protein; Nucleolar complex-associated protein (Noc3p) is ...
221-310 1.84e-33

Nucleolar complex-associated protein; Nucleolar complex-associated protein (Noc3p) is conserved in eukaryotes and has essential roles in replication and rRNA processing in Saccharomyces cerevisiae.


Pssm-ID: 462199  Cd Length: 92  Bit Score: 123.36  E-value: 1.84e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269   221 KEALGIQAQQLLEEPVENLHLIRNIFEKFDSPYITIKKLSLLTLLAVFRDIIPGYKIRPLSEEEQGTKLSKEVAQRWEYE 300
Cdd:pfam07540   3 KEEIASLASSILEDPEENIGLLKRLLKLAESKDVTIRKLALLSLLAVFKDIIPGYRIRPLTEKEKAEKVSKEVKKLREFE 82
                          90
                  ....*....|
gi 19113269   301 QTLLKHYAKF 310
Cdd:pfam07540  83 QSLLKNYKKY 92
 
Name Accession Description Interval E-value
NOC3 COG5117
Protein involved in the nuclear export of pre-ribosomes [Translation, ribosomal structure and ...
25-747 0e+00

Protein involved in the nuclear export of pre-ribosomes [Translation, ribosomal structure and biogenesis / Intracellular trafficking and secretion];


Pssm-ID: 227447 [Multi-domain]  Cd Length: 657  Bit Score: 875.12  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269  25 SSKRNNSQSSTEPRknatsldskkTTKKgvalpeiAERELTQEDIEFFNENPsslkylssinpEDLGKKVekgprpdIYD 104
Cdd:COG5117   1 SSKRNNSQSSTEPR----------TTKK-------AERELTQEDIEFFNENP-----------EDLGKKV-------IYD 45
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 105 LKKSqqfeldtsrlSSDEEsvldyskdsedEQDYELRPRVSSSWNNESYNRLPIKTKDgllqNVVADVNNGEEFLSESES 184
Cdd:COG5117  46 LKKS----------SSDEE-----------EQDYELRPRVSSSWNNESYNRLPIKTKD----NVVADVNNGEEFLSESES 100
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 185 EASLEIDSDIKDEKQKSLEEQKIAPEIPVKQQIKNDKEALGIQAQQLLEEPVENLHLIRNIFEKFDSPYITIKKLSLLTL 264
Cdd:COG5117 101 EASLEIDSDIKDEKQKSLEEQKIAPEIPVKQQIDSEKERIASICTKIIEEPEENLGMMEEVFSMITSMAEKAKKVSYLSL 180
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 265 LAVFRDIIPGYKIRPLSEEEQGTKLSKEVAQRWEYEQTLLKHYAKFLQTLETILKSFSsTLDETQLSLYQVAVRCCTKLI 344
Cdd:COG5117 181 LKVFKAIIPGYKIRPLKEEEQMVKDSKEVLHLKDYEQSLLRWYTSYIKTLVDDVKDES-TLDETQSSLYQVAYISLCELI 259
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 345 EQASHFNLSEKLFALAVRQISHKTKRPGFDGIINSLKNIFEEDNLGKTSLKCVTILSRMFKQRNYDVLPDVYDLFLSVNI 424
Cdd:COG5117 260 QHASHFNCTDKVFSLVLRGILGTTKRPVSMLIIDTIKSKLEEDCTGKTSLVATVIDQMLDKERNPLVLEYVLDIPLSDNS 339
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 425 LNDMKIKDEAWQDDTTNFKKRKKDLPYLTKKARKNYKETKKITQEMKEADAVITAQDKEKYQSEILKIIFITYFKTLQLK 504
Cdd:COG5117 340 LRDEEKARKYWEANKPVSKREKKDIFHLSKKLRKIEKERLRIQSEMRDAEDIEEAIEEEKNQSEILKIIFRLYFMVLKGD 419
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 505 GK-LIGNALEGVARLSHLLNIEFLGDLLQVLRELVMDDtvflPKDKSGVQATREALLTVSTAFEIASAQGVGKLNLDLDl 583
Cdd:COG5117 420 RKdLIGYVLEGLVKYRKIINPEFLGDLLEVLYELLNDN----PLDKISSDARRQALLCILTAFEIASATLYGKENYDLG- 494
                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 584 gLFVQRLYKIIFPFSLNPDADLNLKIKRLKDPDAPSKPFVVNATTEMEMLLKCFQVFFFKSKNISSSRLSSFSKRLAIAS 663
Cdd:COG5117 495 -GFVDLLYSMVHPMNLEPDADLNLKIKRLKDPDAPSKPFVVNATTDNEELLKIVRLLFFKSKQPVHRRHVIFKKRLLYCC 573
                       650       660       670       680       690       700       710       720
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269 664 MQLPEHSASADLALLKKLLSRYSKLSRLLTSEEQIGDGIYNPFIEDPDLSNSSTAVLYEPFLLKNHYSPAVSQSAKELLK 743
Cdd:COG5117 574 SRSPEEFKGAILDISAKLDIRYSDCSNLKCSEFDIGAGNVDSIPSNPDLSNSSTAVLFEYFLLKQHYSPAVSQSAKELLK 653

                ....
gi 19113269 744 STSL 747
Cdd:COG5117 654 STSL 657
NOC3p pfam07540
Nucleolar complex-associated protein; Nucleolar complex-associated protein (Noc3p) is ...
221-310 1.84e-33

Nucleolar complex-associated protein; Nucleolar complex-associated protein (Noc3p) is conserved in eukaryotes and has essential roles in replication and rRNA processing in Saccharomyces cerevisiae.


Pssm-ID: 462199  Cd Length: 92  Bit Score: 123.36  E-value: 1.84e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269   221 KEALGIQAQQLLEEPVENLHLIRNIFEKFDSPYITIKKLSLLTLLAVFRDIIPGYKIRPLSEEEQGTKLSKEVAQRWEYE 300
Cdd:pfam07540   3 KEEIASLASSILEDPEENIGLLKRLLKLAESKDVTIRKLALLSLLAVFKDIIPGYRIRPLTEKEKAEKVSKEVKKLREFE 82
                          90
                  ....*....|
gi 19113269   301 QTLLKHYAKF 310
Cdd:pfam07540  83 QSLLKNYKKY 92
CBF pfam03914
CBF/Mak21 family;
657-735 1.91e-05

CBF/Mak21 family;


Pssm-ID: 461090 [Multi-domain]  Cd Length: 151  Bit Score: 45.27  E-value: 1.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113269   657 KRLAIASMQLPEHSASADLALLKKLLSRY-SKLSRLLTSEEQI-----------GDGIYNPFIEDPDLSNSSTAVLYEPF 724
Cdd:pfam03914  59 KRLLQLALHAPPSFICGILYLISNLLKRHpPSLRSLLHREEEEeeeekekkseeGSDPYDPRKRDPEFSNADESSLWELE 138
                          90
                  ....*....|.
gi 19113269   725 LLKNHYSPAVS 735
Cdd:pfam03914 139 LLLKHYHPSVS 149
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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