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Conserved domains on  [gi|19113346|ref|NP_596554|]
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folding protein [Schizosaccharomyces pombe]

Protein Classification

TAPT1 family protein( domain architecture ID 10526511)

TAPT1 family protein is a DUF747 domain-containing protein; similar to vertebrate transmembrane anterior posterior transformation protein 1 that may be involved in patterning of the vertebrate axial skeleton

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF747 pfam05346
Eukaryotic membrane protein family; This family is a family of eukaryotic membrane proteins. ...
 218-585 2.19e-138

Eukaryotic membrane protein family; This family is a family of eukaryotic membrane proteins. It was previously annotated as including a putative receptor for human cytomegalovirus gH but this has has since been disputed. Analysis of the mouse Tapt1 protein (transmembrane anterior posterior transformation 1) has shown it to be involved in patterning of the vertebrate axial skeleton.


:

Pssm-ID: 398815  Cd Length: 311  Bit Score: 406.51  E-value: 2.19e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113346   218 LPRSRKIDLLKLLLIFSTSILIRKIDVSRLYHIIRAQASIRFYVLYNVLEIADRLCCALGQDVLDCLFSNHILSFNfwnp 297
Cdd:pfam05346   1 LSPAEKCDLLKGLLILISCIILSYLDTSRLYHYIRGQSVIKLYVIYNVLEVADKLLSSFGQDILDALFSTATPRKS---- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113346   298 aGWMTFFYYFAISLAYMVLHTLVLLYQIITLNVTVNSYSNAVLALLMSNQLVEIKGAVFKKFEKENLFQLTCSDVVERFQ 377
Cdd:pfam05346  77 -KILRPILHFILALIYVVLHSLVLLYQVITLNVAINSYSNALLTLLLSNQFVEIKSSVFKKFEKENLFQITCADVVERFQ 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113346   378 ITIMVIIIFLRNLAELYTTSSLdqplltfkrLKTLLAPFFWVIGSELFVDWLKHAFIIKFNYIKPSIYSRFTDVLCHDYV 457
Cdd:pfam05346 156 LFLFLLIIALRNLVEVSSSNDW---------FGTLLGPLLLVLGSEVLVDWLKHAFITKFNNIRPSVYRRFLDVLCKDYL 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113346   458 ASGAQltQTVTGCSQQVARRMGLPVLPLVCVFIRTSMQTWSMFRSTHSMkqeiaksigtifptkdnyvyylpnkeantyn 537
Cdd:pfam05346 227 SSRQK--NAFVDQSHKVTRRLGFPPLPLACLFIRMLPQTYHMLLSTSLP------------------------------- 273

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 19113346   538 agkeaswetlLLSVVRGKSGIAFLFFMAIMLKLLLGKAILAITQSRYE 585
Cdd:pfam05346 274 ----------LISLLTGLLLFLLVFLILLLLKLLLGILLLGYARRRYK 311
 
Name Accession Description Interval E-value
DUF747 pfam05346
Eukaryotic membrane protein family; This family is a family of eukaryotic membrane proteins. ...
 218-585 2.19e-138

Eukaryotic membrane protein family; This family is a family of eukaryotic membrane proteins. It was previously annotated as including a putative receptor for human cytomegalovirus gH but this has has since been disputed. Analysis of the mouse Tapt1 protein (transmembrane anterior posterior transformation 1) has shown it to be involved in patterning of the vertebrate axial skeleton.


Pssm-ID: 398815  Cd Length: 311  Bit Score: 406.51  E-value: 2.19e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113346   218 LPRSRKIDLLKLLLIFSTSILIRKIDVSRLYHIIRAQASIRFYVLYNVLEIADRLCCALGQDVLDCLFSNHILSFNfwnp 297
Cdd:pfam05346   1 LSPAEKCDLLKGLLILISCIILSYLDTSRLYHYIRGQSVIKLYVIYNVLEVADKLLSSFGQDILDALFSTATPRKS---- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113346   298 aGWMTFFYYFAISLAYMVLHTLVLLYQIITLNVTVNSYSNAVLALLMSNQLVEIKGAVFKKFEKENLFQLTCSDVVERFQ 377
Cdd:pfam05346  77 -KILRPILHFILALIYVVLHSLVLLYQVITLNVAINSYSNALLTLLLSNQFVEIKSSVFKKFEKENLFQITCADVVERFQ 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113346   378 ITIMVIIIFLRNLAELYTTSSLdqplltfkrLKTLLAPFFWVIGSELFVDWLKHAFIIKFNYIKPSIYSRFTDVLCHDYV 457
Cdd:pfam05346 156 LFLFLLIIALRNLVEVSSSNDW---------FGTLLGPLLLVLGSEVLVDWLKHAFITKFNNIRPSVYRRFLDVLCKDYL 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113346   458 ASGAQltQTVTGCSQQVARRMGLPVLPLVCVFIRTSMQTWSMFRSTHSMkqeiaksigtifptkdnyvyylpnkeantyn 537
Cdd:pfam05346 227 SSRQK--NAFVDQSHKVTRRLGFPPLPLACLFIRMLPQTYHMLLSTSLP------------------------------- 273

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 19113346   538 agkeaswetlLLSVVRGKSGIAFLFFMAIMLKLLLGKAILAITQSRYE 585
Cdd:pfam05346 274 ----------LISLLTGLLLFLLVFLILLLLKLLLGILLLGYARRRYK 311
 
Name Accession Description Interval E-value
DUF747 pfam05346
Eukaryotic membrane protein family; This family is a family of eukaryotic membrane proteins. ...
 218-585 2.19e-138

Eukaryotic membrane protein family; This family is a family of eukaryotic membrane proteins. It was previously annotated as including a putative receptor for human cytomegalovirus gH but this has has since been disputed. Analysis of the mouse Tapt1 protein (transmembrane anterior posterior transformation 1) has shown it to be involved in patterning of the vertebrate axial skeleton.


Pssm-ID: 398815  Cd Length: 311  Bit Score: 406.51  E-value: 2.19e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113346   218 LPRSRKIDLLKLLLIFSTSILIRKIDVSRLYHIIRAQASIRFYVLYNVLEIADRLCCALGQDVLDCLFSNHILSFNfwnp 297
Cdd:pfam05346   1 LSPAEKCDLLKGLLILISCIILSYLDTSRLYHYIRGQSVIKLYVIYNVLEVADKLLSSFGQDILDALFSTATPRKS---- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113346   298 aGWMTFFYYFAISLAYMVLHTLVLLYQIITLNVTVNSYSNAVLALLMSNQLVEIKGAVFKKFEKENLFQLTCSDVVERFQ 377
Cdd:pfam05346  77 -KILRPILHFILALIYVVLHSLVLLYQVITLNVAINSYSNALLTLLLSNQFVEIKSSVFKKFEKENLFQITCADVVERFQ 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113346   378 ITIMVIIIFLRNLAELYTTSSLdqplltfkrLKTLLAPFFWVIGSELFVDWLKHAFIIKFNYIKPSIYSRFTDVLCHDYV 457
Cdd:pfam05346 156 LFLFLLIIALRNLVEVSSSNDW---------FGTLLGPLLLVLGSEVLVDWLKHAFITKFNNIRPSVYRRFLDVLCKDYL 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113346   458 ASGAQltQTVTGCSQQVARRMGLPVLPLVCVFIRTSMQTWSMFRSTHSMkqeiaksigtifptkdnyvyylpnkeantyn 537
Cdd:pfam05346 227 SSRQK--NAFVDQSHKVTRRLGFPPLPLACLFIRMLPQTYHMLLSTSLP------------------------------- 273

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 19113346   538 agkeaswetlLLSVVRGKSGIAFLFFMAIMLKLLLGKAILAITQSRYE 585
Cdd:pfam05346 274 ----------LISLLTGLLLFLLVFLILLLLKLLLGILLLGYARRRYK 311
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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