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Conserved domains on  [gi|19113486|ref|NP_596694|]
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FKBP-type peptidyl-prolyl cis-trans isomerase [Schizosaccharomyces pombe]

Protein Classification

FKBP-type peptidyl-prolyl cis-trans isomerase( domain architecture ID 16050428)

FKBP-type peptidyl-prolyl cis-trans isomerase accelerates the folding of proteins; it catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides

EC:  5.2.1.8
Gene Ontology:  GO:0003755

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
FkpA COG0545
FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein ...
259-360 7.54e-36

FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 440311 [Multi-domain]  Cd Length: 104  Bit Score: 126.06  E-value: 7.54e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113486 259 VVVTDVKTGSGASATNGKKVEMRYIGKLENGKVFDKNTK-GKPFAFILGRGEVIRGWDVGVAGMQEGGERKITIPAPMAY 337
Cdd:COG0545   1 LQYKVLKEGTGAKPKAGDTVTVHYTGTLLDGTVFDSSYDrGEPATFPLGVGQVIPGWDEGLQGMKVGGKRRLVIPPELAY 80
                        90       100
                ....*....|....*....|....
gi 19113486 338 GNQSIPG-IPKNSTLVFEVKLVRV 360
Cdd:COG0545  81 GERGAGGvIPPNSTLVFEVELLDV 104
NPL pfam17800
Nucleoplasmin-like domain;
7-121 4.56e-23

Nucleoplasmin-like domain;


:

Pssm-ID: 465511  Cd Length: 90  Bit Score: 91.90  E-value: 4.56e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113486     7 VYSLSVK-GKDVPAVeesTDASIHLTMASIDAGEKsnKPTTLLVKVrpripvededdeeldeqmqellEESQREFVLCTL 85
Cdd:pfam17800   1 FWGLEVPpGKPVTLE---VPEDLHITNAALGPSAK--PETVVKVKV----------------------DDEEEEFVLCTL 53
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 19113486    86 KPGSLYQQPLNLTITPGDEVFFSASGDATIHLSGNF 121
Cdd:pfam17800  54 TPGKVEQQPLDLVFSEGEEVTFSVKGKNTVHLTGYY 89
 
Name Accession Description Interval E-value
FkpA COG0545
FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein ...
259-360 7.54e-36

FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440311 [Multi-domain]  Cd Length: 104  Bit Score: 126.06  E-value: 7.54e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113486 259 VVVTDVKTGSGASATNGKKVEMRYIGKLENGKVFDKNTK-GKPFAFILGRGEVIRGWDVGVAGMQEGGERKITIPAPMAY 337
Cdd:COG0545   1 LQYKVLKEGTGAKPKAGDTVTVHYTGTLLDGTVFDSSYDrGEPATFPLGVGQVIPGWDEGLQGMKVGGKRRLVIPPELAY 80
                        90       100
                ....*....|....*....|....
gi 19113486 338 GNQSIPG-IPKNSTLVFEVKLVRV 360
Cdd:COG0545  81 GERGAGGvIPPNSTLVFEVELLDV 104
FKBP_C pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase;
272-358 9.76e-35

FKBP-type peptidyl-prolyl cis-trans isomerase;


Pssm-ID: 459735  Cd Length: 94  Bit Score: 122.69  E-value: 9.76e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113486   272 ATNGKKVEMRYIGKLENGKVFDKNT-KGKPFAFILGRGEVIRGWDVGVAGMQEGGERKITIPAPMAYGNQSIPG--IPKN 348
Cdd:pfam00254   5 AKKGDRVTVHYTGTLEDGTVFDSSYdRGKPFEFTLGSGQVIPGWDEGLVGMKVGEKRKLTIPPELAYGEEGLAGpvIPPN 84
                          90
                  ....*....|
gi 19113486   349 STLVFEVKLV 358
Cdd:pfam00254  85 ATLVFEVELL 94
NPL pfam17800
Nucleoplasmin-like domain;
7-121 4.56e-23

Nucleoplasmin-like domain;


Pssm-ID: 465511  Cd Length: 90  Bit Score: 91.90  E-value: 4.56e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113486     7 VYSLSVK-GKDVPAVeesTDASIHLTMASIDAGEKsnKPTTLLVKVrpripvededdeeldeqmqellEESQREFVLCTL 85
Cdd:pfam17800   1 FWGLEVPpGKPVTLE---VPEDLHITNAALGPSAK--PETVVKVKV----------------------DDEEEEFVLCTL 53
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 19113486    86 KPGSLYQQPLNLTITPGDEVFFSASGDATIHLSGNF 121
Cdd:pfam17800  54 TPGKVEQQPLDLVFSEGEEVTFSVKGKNTVHLTGYY 89
PRK10902 PRK10902
FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional
232-360 4.05e-18

FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional


Pssm-ID: 236791 [Multi-domain]  Cd Length: 269  Bit Score: 82.89  E-value: 4.05e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113486  232 GPAAKKEKQQASSNAPSSPKTR----------TLKGGVVVTDVKTGSGASATNGKKVEMRYIGKLENGKVFDKN-TKGKP 300
Cdd:PRK10902 111 SAAQAKMEKDAADNEAKGKKYRekfakekgvkTTSTGLLYKVEKEGTGEAPKDSDTVVVNYKGTLIDGKEFDNSyTRGEP 190
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113486  301 FAFILGRgeVIRGWDVGVAGMQEGGERKITIPAPMAYGNQSIPGIPKNSTLVFEVKLVRV 360
Cdd:PRK10902 191 LSFRLDG--VIPGWTEGLKNIKKGGKIKLVIPPELAYGKAGVPGIPANSTLVFDVELLDV 248
 
Name Accession Description Interval E-value
FkpA COG0545
FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein ...
259-360 7.54e-36

FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440311 [Multi-domain]  Cd Length: 104  Bit Score: 126.06  E-value: 7.54e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113486 259 VVVTDVKTGSGASATNGKKVEMRYIGKLENGKVFDKNTK-GKPFAFILGRGEVIRGWDVGVAGMQEGGERKITIPAPMAY 337
Cdd:COG0545   1 LQYKVLKEGTGAKPKAGDTVTVHYTGTLLDGTVFDSSYDrGEPATFPLGVGQVIPGWDEGLQGMKVGGKRRLVIPPELAY 80
                        90       100
                ....*....|....*....|....
gi 19113486 338 GNQSIPG-IPKNSTLVFEVKLVRV 360
Cdd:COG0545  81 GERGAGGvIPPNSTLVFEVELLDV 104
FKBP_C pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase;
272-358 9.76e-35

FKBP-type peptidyl-prolyl cis-trans isomerase;


Pssm-ID: 459735  Cd Length: 94  Bit Score: 122.69  E-value: 9.76e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113486   272 ATNGKKVEMRYIGKLENGKVFDKNT-KGKPFAFILGRGEVIRGWDVGVAGMQEGGERKITIPAPMAYGNQSIPG--IPKN 348
Cdd:pfam00254   5 AKKGDRVTVHYTGTLEDGTVFDSSYdRGKPFEFTLGSGQVIPGWDEGLVGMKVGEKRKLTIPPELAYGEEGLAGpvIPPN 84
                          90
                  ....*....|
gi 19113486   349 STLVFEVKLV 358
Cdd:pfam00254  85 ATLVFEVELL 94
NPL pfam17800
Nucleoplasmin-like domain;
7-121 4.56e-23

Nucleoplasmin-like domain;


Pssm-ID: 465511  Cd Length: 90  Bit Score: 91.90  E-value: 4.56e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113486     7 VYSLSVK-GKDVPAVeesTDASIHLTMASIDAGEKsnKPTTLLVKVrpripvededdeeldeqmqellEESQREFVLCTL 85
Cdd:pfam17800   1 FWGLEVPpGKPVTLE---VPEDLHITNAALGPSAK--PETVVKVKV----------------------DDEEEEFVLCTL 53
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 19113486    86 KPGSLYQQPLNLTITPGDEVFFSASGDATIHLSGNF 121
Cdd:pfam17800  54 TPGKVEQQPLDLVFSEGEEVTFSVKGKNTVHLTGYY 89
PRK10902 PRK10902
FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional
232-360 4.05e-18

FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional


Pssm-ID: 236791 [Multi-domain]  Cd Length: 269  Bit Score: 82.89  E-value: 4.05e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113486  232 GPAAKKEKQQASSNAPSSPKTR----------TLKGGVVVTDVKTGSGASATNGKKVEMRYIGKLENGKVFDKN-TKGKP 300
Cdd:PRK10902 111 SAAQAKMEKDAADNEAKGKKYRekfakekgvkTTSTGLLYKVEKEGTGEAPKDSDTVVVNYKGTLIDGKEFDNSyTRGEP 190
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113486  301 FAFILGRgeVIRGWDVGVAGMQEGGERKITIPAPMAYGNQSIPGIPKNSTLVFEVKLVRV 360
Cdd:PRK10902 191 LSFRLDG--VIPGWTEGLKNIKKGGKIKLVIPPELAYGKAGVPGIPANSTLVFDVELLDV 248
SlpA COG1047
Peptidyl-prolyl cis-trans isomerase, FKBP type [Posttranslational modification, protein ...
272-355 6.98e-15

Peptidyl-prolyl cis-trans isomerase, FKBP type [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440668 [Multi-domain]  Cd Length: 138  Bit Score: 70.90  E-value: 6.98e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113486 272 ATNGKKVEMRYIGKLENGKVFDKNTKGKPFAFILGRGEVIRGWDVGVAGMQEGGERKITIPAPMAYGnqsipgiPKNSTL 351
Cdd:COG1047   1 IEKGDVVTLHYTLKLEDGEVFDSTFEGEPLEFLHGAGQLIPGLEEALEGMEVGDKKTVTLPPEEAYG-------ERDPEL 73

                ....
gi 19113486 352 VFEV 355
Cdd:COG1047  74 VQTV 77
PRK11570 PRK11570
peptidyl-prolyl cis-trans isomerase; Provisional
234-360 1.53e-09

peptidyl-prolyl cis-trans isomerase; Provisional


Pssm-ID: 183207 [Multi-domain]  Cd Length: 206  Bit Score: 57.11  E-value: 1.53e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113486  234 AAKKEKQQA---------SSNAPSSPKTRTlKGGVVVTDVKTGSGASATNGKKVEMRYIGKLENGKVFDKNT-KGKPFAF 303
Cdd:PRK11570  71 AVRRERQQAmaaegvkflEENAKKEGVNST-ESGLQFRVLTQGEGAIPARTDRVRVHYTGKLIDGTVFDSSVaRGEPAEF 149
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 19113486  304 ILgrGEVIRGWDVGVAGMQEGGERKITIPAPMAYGNQSI-PGIPKNSTLVFEVKLVRV 360
Cdd:PRK11570 150 PV--NGVIPGWIEALTLMPVGSKWELTIPHELAYGERGAgASIPPFSTLVFEVELLEI 205
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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