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Conserved domains on  [gi|24582701|ref|NP_609182|]
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uncharacterized protein Dmel_CG8673 [Drosophila melanogaster]

Protein Classification

glycosyltransferase family protein( domain architecture ID 229488)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Galactosyl_T super family cl21608
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 186-374 1.52e-43

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


The actual alignment was detected with superfamily member pfam01762:

Pssm-ID: 473923 [Multi-domain]  Cd Length: 195  Bit Score: 150.94  E-value: 1.52e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582701   186 AARMSIRQTWMHYGSRRDVGMA--FVLGKGK--NKSVKKAIDQEDFMYQDLIRGHFIDSYNNLTLKTISLLEWADLHCPK 261
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGRIKslFLVGLSAdtDGKVADLVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKCPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582701   262 AKYVLKTDDDMFINVPKLLTLISTLKANRT---IYGRRAENWKPIRNRWSKYHISNAQYGKPTFPYFTTGPAYLLTGDIV 338
Cdd:pfam01762  81 AKYIGKIDDDVYFFPDKLLSLLDNGNIDPSessFYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFYVLSRDAA 160

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 24582701   339 HALYVQSLNTAFLKLEDVFtTGIVAESLNIRRVNVR 374
Cdd:pfam01762 161 EKLLKASKHRRFLQIEDVY-VGILANDLGISRVNLP 195
 
Name Accession Description Interval E-value
Galactosyl_T pfam01762
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 186-374 1.52e-43

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


Pssm-ID: 426415 [Multi-domain]  Cd Length: 195  Bit Score: 150.94  E-value: 1.52e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582701   186 AARMSIRQTWMHYGSRRDVGMA--FVLGKGK--NKSVKKAIDQEDFMYQDLIRGHFIDSYNNLTLKTISLLEWADLHCPK 261
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGRIKslFLVGLSAdtDGKVADLVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKCPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582701   262 AKYVLKTDDDMFINVPKLLTLISTLKANRT---IYGRRAENWKPIRNRWSKYHISNAQYGKPTFPYFTTGPAYLLTGDIV 338
Cdd:pfam01762  81 AKYIGKIDDDVYFFPDKLLSLLDNGNIDPSessFYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFYVLSRDAA 160

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 24582701   339 HALYVQSLNTAFLKLEDVFtTGIVAESLNIRRVNVR 374
Cdd:pfam01762 161 EKLLKASKHRRFLQIEDVY-VGILANDLGISRVNLP 195
PLN03133 PLN03133
beta-1,3-galactosyltransferase; Provisional
 188-356 1.91e-23

beta-1,3-galactosyltransferase; Provisional


Pssm-ID: 215596 [Multi-domain]  Cd Length: 636  Bit Score: 102.96  E-value: 1.91e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582701  188 RMSIRQTWMHYGSRR--DVGMAFVLGKGKNKSVKKAIDQEDFMYQDLIRGHFIDSYNNLTLKTISLLEWAdLHCPKAKYV 265
Cdd:PLN03133 401 RMAVRRTWMQYDAVRsgAVAVRFFVGLHKNQMVNEELWNEARTYGDIQLMPFVDYYSLITWKTLAICIFG-TEVVSAKYV 479

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582701  266 LKTDDDMFINVPKLLTLISTLKANR-TIYGRRAENWKPIRNRWSKYHISNAQYGKPTFPYFTTGPAYLLTGDIVHALY-- 342
Cdd:PLN03133 480 MKTDDDAFVRVDEVLASLKRTNVSHgLLYGLINSDSQPHRNPDSKWYISPEEWPEETYPPWAHGPGYVVSRDIAKEVYkr 559

                        170
                 ....*....|....
gi 24582701  343 VQSLNTAFLKLEDV 356
Cdd:PLN03133 560 HKEGRLKMFKLEDV 573
 
Name Accession Description Interval E-value
Galactosyl_T pfam01762
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 186-374 1.52e-43

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


Pssm-ID: 426415 [Multi-domain]  Cd Length: 195  Bit Score: 150.94  E-value: 1.52e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582701   186 AARMSIRQTWMHYGSRRDVGMA--FVLGKGK--NKSVKKAIDQEDFMYQDLIRGHFIDSYNNLTLKTISLLEWADLHCPK 261
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGRIKslFLVGLSAdtDGKVADLVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKCPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582701   262 AKYVLKTDDDMFINVPKLLTLISTLKANRT---IYGRRAENWKPIRNRWSKYHISNAQYGKPTFPYFTTGPAYLLTGDIV 338
Cdd:pfam01762  81 AKYIGKIDDDVYFFPDKLLSLLDNGNIDPSessFYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFYVLSRDAA 160

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 24582701   339 HALYVQSLNTAFLKLEDVFtTGIVAESLNIRRVNVR 374
Cdd:pfam01762 161 EKLLKASKHRRFLQIEDVY-VGILANDLGISRVNLP 195
PLN03133 PLN03133
beta-1,3-galactosyltransferase; Provisional
 188-356 1.91e-23

beta-1,3-galactosyltransferase; Provisional


Pssm-ID: 215596 [Multi-domain]  Cd Length: 636  Bit Score: 102.96  E-value: 1.91e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582701  188 RMSIRQTWMHYGSRR--DVGMAFVLGKGKNKSVKKAIDQEDFMYQDLIRGHFIDSYNNLTLKTISLLEWAdLHCPKAKYV 265
Cdd:PLN03133 401 RMAVRRTWMQYDAVRsgAVAVRFFVGLHKNQMVNEELWNEARTYGDIQLMPFVDYYSLITWKTLAICIFG-TEVVSAKYV 479

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582701  266 LKTDDDMFINVPKLLTLISTLKANR-TIYGRRAENWKPIRNRWSKYHISNAQYGKPTFPYFTTGPAYLLTGDIVHALY-- 342
Cdd:PLN03133 480 MKTDDDAFVRVDEVLASLKRTNVSHgLLYGLINSDSQPHRNPDSKWYISPEEWPEETYPPWAHGPGYVVSRDIAKEVYkr 559

                        170
                 ....*....|....
gi 24582701  343 VQSLNTAFLKLEDV 356
Cdd:PLN03133 560 HKEGRLKMFKLEDV 573
PLN03193 PLN03193
beta-1,3-galactosyltransferase; Provisional
 120-371 6.18e-07

beta-1,3-galactosyltransferase; Provisional


Pssm-ID: 178735 [Multi-domain]  Cd Length: 408  Bit Score: 51.12  E-value: 6.18e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582701  120 DSKDILAKKSVVLYSIDTevpvrmpLVKTIykpGHLDSEI------------------DMERICPQKGLSTQLLVLITSS 181
Cdd:PLN03193  79 DSKDIIGEVSKTHNAIQT-------LDKTI---SNLEMELaaaraaqesilngspiseDLKKTQSSGKRRYLMVVGINTA 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582701  182 LRHSAARMSIRQTWMHYGSRRD-------VGMAFVLGKGKNKS--VKKAIDQEDFMYQDLIRGHFIDSYNNLTLKTISLL 252
Cdd:PLN03193 149 FSSRKRRDSVRATWMPQGEKRKkleeekgIIIRFVIGHSATSGgiLDRAIEAEDRKHGDFLRLDHVEGYLELSAKTKTYF 228

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582701  253 EWAdLHCPKAKYVLKTDDDMFINVPKL-LTLISTLKANRTIYGRRAENwkPIRN-RWSKYHISNA-QYGKPTFPYF--TT 327
Cdd:PLN03193 229 ATA-VAMWDADFYVKVDDDVHVNIATLgETLVRHRKKPRVYIGCMKSG--PVLSqKGVRYHEPEYwKFGENGNKYFrhAT 305

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 24582701  328 GPAYLLTGDIvhALYVqSLNTAFLKL---EDV----FTTGIVAESLNIRRV 371
Cdd:PLN03193 306 GQLYAISKDL--ASYI-SINQHVLHKyanEDVslgsWFIGLDVEHIDDRRL 353
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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