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Conserved domains on  [gi|62484238|ref|NP_609511|]
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uncharacterized protein Dmel_CG6614, isoform A [Drosophila melanogaster]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11419012)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
886-1012 2.64e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 70.81  E-value: 2.64e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  886 GSVEYSRGRCDEALKYFQELLSVvDPMDnllfKLSFLRLGQLALQRKQYELAEKAFNICLPARRKNFIANYGMGLTLYHL 965
Cdd:COG0457   15 GLAYRRLGRYEEAIEDYEKALEL-DPDD----AEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQAL 89

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 62484238  966 NRLEEAIPYLSRCTEVDIFIPDVWGYLATINLRLSRNKTALECWKVA 1012
Cdd:COG0457   90 GRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERA 136
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
886-1012 2.64e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 70.81  E-value: 2.64e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  886 GSVEYSRGRCDEALKYFQELLSVvDPMDnllfKLSFLRLGQLALQRKQYELAEKAFNICLPARRKNFIANYGMGLTLYHL 965
Cdd:COG0457   15 GLAYRRLGRYEEAIEDYEKALEL-DPDD----AEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQAL 89

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 62484238  966 NRLEEAIPYLSRCTEVDIFIPDVWGYLATINLRLSRNKTALECWKVA 1012
Cdd:COG0457   90 GRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERA 136
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 922-977 5.76e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 39.24  E-value: 5.76e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 62484238    922 LRLGQLALQRKQYELAEKAFNICL---PARRKNFIANYGMGLTLYHLNRLEEAIPYLSR 977
Cdd:pfam13432    1 LALARAALRAGDYDDAAAALEAALarfPESPDAAAALLLLGLAALRQGRLAEAAAAYRA 59
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
886-1012 2.64e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 70.81  E-value: 2.64e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  886 GSVEYSRGRCDEALKYFQELLSVvDPMDnllfKLSFLRLGQLALQRKQYELAEKAFNICLPARRKNFIANYGMGLTLYHL 965
Cdd:COG0457   15 GLAYRRLGRYEEAIEDYEKALEL-DPDD----AEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQAL 89

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 62484238  966 NRLEEAIPYLSRCTEVDIFIPDVWGYLATINLRLSRNKTALECWKVA 1012
Cdd:COG0457   90 GRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERA 136
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 881-1017 1.23e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 66.37  E-value: 1.23e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  881 QLHINGSVEYSRGRCDEALKYFQELLSVvDPmDNLLFklsFLRLGQLALQRKQYELAEKAFNICLPARRKNFIANYGMGL 960
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALEL-DP-DNPEA---FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGL 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 62484238  961 TLYHLNRLEEAIPYLSRCTEVDIFIPDVWGYLATINLRLSRNKTALECWKVA-KLYPE 1017
Cdd:COG4783   81 ALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKAlELDPD 138
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
886-1010 1.34e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 68.88  E-value: 1.34e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  886 GSVEYSRGRCDEALKYFQELLSVvdpmdNLLFKLSFLRLGQLALQRKQYELAEKAFNICLPARRKNFIANYGMGLTLYHL 965
Cdd:COG0457   49 GLAYLRLGRYEEALADYEQALEL-----DPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLEL 123

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 62484238  966 NRLEEAIPYLSRCTEVDIFIPDVWGYLATINLRLSRNKTALECWK 1010
Cdd:COG0457  124 GRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLE 168
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 881-1017 5.82e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.20  E-value: 5.82e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  881 QLHIN-GSVEYSRGRCDEALKYFQELLSVVDPMDNLLFklsflRLGQLALQRKQYELAEKAFNICLPARRKNFIANYGMG 959
Cdd:COG2956   43 EAHLAlGNLYRRRGEYDRAIRIHQKLLERDPDRAEALL-----ELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLA 117

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 62484238  960 LTLYHLNRLEEAIPYLSRCTEVDIFIPDVWGYLATINLRLSRNKTALECWKVA-KLYPE 1017
Cdd:COG2956  118 EIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKAlKLDPD 176
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
920-1017 7.06e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 57.71  E-value: 7.06e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  920 SFLRLGQLALQRKQYELAEKAFNICLPARRKNFIANYGMGLTLYHLNRLEEAIPYLSRCTEVDIFIPDVWGYLATINLRL 999
Cdd:COG0457   10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQAL 89

                         90
                 ....*....|....*....
gi 62484238 1000 SRNKTALECW-KVAKLYPE 1017
Cdd:COG0457   90 GRYEEALEDYdKALELDPD 108
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
927-1017 5.13e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 51.71  E-value: 5.13e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  927 LALQRKQYELAEKAFNICLPARRKNFIANYGMGLTLYHLNRLEEAIPYlSRCTEVDIFIPDVWGYLATINLRLSRNKTAL 1006
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|..
gi 62484238 1007 ECWKVA-KLYPE 1017
Cdd:COG3063   80 AYLERAlELDPS 91
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 921-1031 1.17e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.55  E-value: 1.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  921 FLRLGQLALQRKQYELAEKAFNICLPARRKNFIANYGMGLTLYHLNRLEEAIPYLSRCTEVDIFIPDVWGYLATINLRLS 1000
Cdd:COG4235   20 WLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQG 99

                         90       100       110
                 ....*....|....*....|....*....|..
gi 62484238 1001 RNKTALECW-KVAKLYPEVSISKSVYAELDKI 1031
Cdd:COG4235  100 DYAEAIAAWqKLLALLPADAPARLLEASIAEA 131
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 896-1012 1.37e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 52.27  E-value: 1.37e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  896 DEALKYFQELLSVVDPMDNLLFKLSFLRLGQLALQRKQYELAEKAFNICLPARRKNFIANYGMGLTLYHLNRLEEAIPYL 975
Cdd:COG5010   32 AGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYY 111

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 62484238  976 SRCTEVDIFIPDVWGYLATINLRLSRNKTALECWKVA 1012
Cdd:COG5010  112 EKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRA 148
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 879-982 2.71e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 54.61  E-value: 2.71e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  879 CYQLHIN-GSVEYSRGRCDEALKYFQELLSvVDPmDNLLFklsFLRLGQLALQRKQYELAEKAFNICLPARRKNFIANYG 957
Cdd:COG3914  111 NAEALFNlGNLLLALGRLEEALAALRRALA-LNP-DFAEA---YLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNN 185

                         90       100
                 ....*....|....*....|....*
gi 62484238  958 MGLTLYHLNRLEEAIPYLSRCTEVD 982
Cdd:COG3914  186 LGNALQDLGRLEEAIAAYRRALELD 210
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 896-1017 5.19e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 52.42  E-value: 5.19e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  896 DEALKYFQELLSvVDPmDNLLFklsFLRLGQLALQRKQYELAEKAFNICLPARRKNFIANYGMGLTLYHLNRLEEAIPYL 975
Cdd:COG2956   25 DKAIDLLEEALE-LDP-ETVEA---HLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELL 99

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 62484238  976 SRCTEVDIFIPDVWGYLATINLRLSRNKTALECW-KVAKLYPE 1017
Cdd:COG2956  100 EKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLeRLLKLGPE 142
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
886-977 1.55e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.78  E-value: 1.55e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  886 GSVEYSRGRCDEALKYFQELLSVvDPMDnllfKLSFLRLGQLALQRKQYELAEKAFNICLPARRKNFIANYGMGLTLYHL 965
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALEL-DPDD----AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKL 157

                         90
                 ....*....|..
gi 62484238  966 NRLEEAIPYLSR 977
Cdd:COG0457  158 GRYEEALELLEK 169
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
890-989 2.72e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 46.70  E-value: 2.72e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  890 YSRGRCDEALKYFQELLSVvDPMDNLlfklSFLRLGQLALQRKQYELAEkAFNICLPARRKNFIANYGMGLTLYHLNRLE 969
Cdd:COG3063    3 LKLGDLEEAEEYYEKALEL-DPDNAD----ALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYD 76

                         90       100
                 ....*....|....*....|
gi 62484238  970 EAIPYLSRCTEVDifiPDVW 989
Cdd:COG3063   77 EALAYLERALELD---PSAL 93
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 890-977 3.62e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 48.03  E-value: 3.62e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  890 YSRGRCDEALKYFQELLSvVDPMDNLLfklsFLRLGQLALQRKQYELAEKAFNICLPARRKNFIANYGMGLTLYHLNRLE 969
Cdd:COG5010   65 NKLGDFEESLALLEQALQ-LDPNNPEL----YYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDD 139


                 ....*...
gi 62484238  970 EAIPYLSR 977
Cdd:COG5010  140 EAKAALQR 147
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 928-1031 3.81e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 46.91  E-value: 3.81e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  928 ALQRKQYELAEKAFniclparrKNFI-----------ANYGMGLTLYHLNRLEEAIPYLSRCTEV---DIFIPDVWGYLA 993
Cdd:COG1729    3 LLKAGDYDEAIAAF--------KAFLkrypnsplapdALYWLGEAYYALGDYDEAAEAFEKLLKRypdSPKAPDALLKLG 74

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 62484238  994 TINLRLSRNKTALECW-KVAKLYPEVSISKSVYAELDKI 1031
Cdd:COG1729   75 LSYLELGDYDKARATLeELIKKYPDSEAAKEARARLARL 113
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 896-1019 7.63e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.96  E-value: 7.63e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  896 DEALKYFQELLSVVDPMDNLLFklsflRLGQLALQRKQYELAEKAFNICLPARRKNFIANYGMGLTLYHLNRLEEAIPYL 975
Cdd:COG2956  127 EKAIEVLERLLKLGPENAHAYC-----ELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAAL 201

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 62484238  976 SRCTEVDIFIPDVWGYLATINLRLSRNKTALECW-KVAKLYPEVS 1019
Cdd:COG2956  202 ERALEQDPDYLPALPRLAELYEKLGDPEEALELLrKALELDPSDD 246
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
881-993 8.36e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 45.29  E-value: 8.36e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  881 QLHIN-GSVEYSRGRCDEALKYFQELLSVvDPmdnlLFKLSFLRLGQLALQRKQYELAEKAFNICLPARRKNFIANYGMG 959
Cdd:COG4785   74 QLYYErGVAYDSLGDYDLAIADFDQALEL-DP----DLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRG 148

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 62484238  960 LTLYHLNRLEEAIPYLSRCTEVDIFIPD--VWGYLA 993
Cdd:COG4785  149 IALYYLGRYELAIADLEKALELDPNDPEraLWLYLA 184
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 886-978 2.44e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.92  E-value: 2.44e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  886 GSVEYSRGRCDEALKYFQELLSvVDPMDNLLfklsFLRLGQLALQRKQYELAEKAFNICLPARRKNFIANYGMGLTLYHL 965
Cdd:COG4235   24 GRAYLRLGRYDEALAAYEKALR-LDPDNADA----LLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQ 98

                         90
                 ....*....|...
gi 62484238  966 NRLEEAIPYLSRC 978
Cdd:COG4235   99 GDYAEAIAAWQKL 111
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 890-977 3.20e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.13  E-value: 3.20e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  890 YSRGRCDEALKYFQELLSVvDPmDNLLFKLSFLRLGQLALQRKQYELAEKAFNICL---PARRKNFIANYGMGLTLYHLN 966
Cdd:COG1729    4 LKAGDYDEAIAAFKAFLKR-YP-NSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLkryPDSPKAPDALLKLGLSYLELG 81

                         90
                 ....*....|.
gi 62484238  967 RLEEAIPYLSR 977
Cdd:COG1729   82 DYDKARATLEE 92
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 922-977 5.76e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 39.24  E-value: 5.76e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 62484238    922 LRLGQLALQRKQYELAEKAFNICL---PARRKNFIANYGMGLTLYHLNRLEEAIPYLSR 977
Cdd:pfam13432    1 LALARAALRAGDYDDAAAALEAALarfPESPDAAAALLLLGLAALRQGRLAEAAAAYRA 59
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
950-1017 8.85e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 42.30  E-value: 8.85e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 62484238  950 KNFIANYGMGLTLYHLNRLEEAIPYLSRCTEVDIFIPDVWGYLATINLRLSRNKTALECW-KVAKLYPE 1017
Cdd:COG0457    6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYeQALELDPD 74
TPR_12 pfam13424
Tetratricopeptide repeat;
922-981 1.31e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.52  E-value: 1.31e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 62484238    922 LRLGQLALQRKQYELAEKAFNICLPARRKNFIAN--------YGMGLTLYHLNRLEEAIPYLSRCTEV 981
Cdd:pfam13424    7 NNLAAVLRRLGRYDEALELLEKALEIARRLLGPDhpltattlLNLGRLYLELGRYEEALELLERALAL 74
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 922-1017 1.37e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 42.67  E-value: 1.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484238  922 LRLGQLALQRKQYELAEKAFNICLPARRKNFIANYGMGLTLYHLNRLEEAIPYLSRCTEVDIFIPDVWGYLATINLRLSR 1001
Cdd:COG3914   82 ELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGR 161

                         90
                 ....*....|....*..
gi 62484238 1002 NKTALECWKVA-KLYPE 1017
Cdd:COG3914  162 LEEAIAALRRAlELDPD 178
TPR_12 pfam13424
Tetratricopeptide repeat;
882-950 1.77e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.14  E-value: 1.77e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 62484238    882 LHINGSVEYSRGRCDEALKYFQELLSVV----DPmDNLLFKLSFLRLGQLALQRKQYELAEKAFNICLPARRK 950
Cdd:pfam13424    6 LNNLAAVLRRLGRYDEALELLEKALEIArrllGP-DHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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