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Conserved domains on  [gi|24584938|ref|NP_609869|]
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uncharacterized protein Dmel_CG5783 [Drosophila melanogaster]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 10552919)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate; similar to the C-terminal region of the D. melanogaster hypothetical protein FR47

CATH:  3.40.630.30
EC:  2.3.1.-
Gene Ontology:  GO:0008080
PubMed:  15581578|9175471|10940244
SCOP:  3000403

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FR47 pfam08445
FR47-like protein; The members of this family are similar to the C-terminal region of the D. ...
 187-272 4.99e-39

FR47-like protein; The members of this family are similar to the C-terminal region of the D. melanogaster hypothetical protein FR47. This protein has been found to consist of two N-acyltransferase-like domains swapped with the C-terminal strands.


:

Pssm-ID: 117022 [Multi-domain]  Cd Length: 86  Bit Score: 131.68  E-value: 4.99e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584938   187 SVGLYQEDTQELVAWCIRLQGGYLGALQVKDTHKRRGFGSVVTREIAYRLAVQGHDVMALVGPSNKPSSEMFSKLGFQVI 266
Cdd:pfam08445   1 VLGIYRGDTGELAAWCLRLPGGELGALQTLPEHRRRGLGSRLVAALARGIAERGITPFAVVVAGNTPSRRLYEKLGFRKI 80


                  ....*.
gi 24584938   267 DQCYWL 272
Cdd:pfam08445  81 DETYWV 86
 
Name Accession Description Interval E-value
FR47 pfam08445
FR47-like protein; The members of this family are similar to the C-terminal region of the D. ...
 187-272 4.99e-39

FR47-like protein; The members of this family are similar to the C-terminal region of the D. melanogaster hypothetical protein FR47. This protein has been found to consist of two N-acyltransferase-like domains swapped with the C-terminal strands.


Pssm-ID: 117022 [Multi-domain]  Cd Length: 86  Bit Score: 131.68  E-value: 4.99e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584938   187 SVGLYQEDTQELVAWCIRLQGGYLGALQVKDTHKRRGFGSVVTREIAYRLAVQGHDVMALVGPSNKPSSEMFSKLGFQVI 266
Cdd:pfam08445   1 VLGIYRGDTGELAAWCLRLPGGELGALQTLPEHRRRGLGSRLVAALARGIAERGITPFAVVVAGNTPSRRLYEKLGFRKI 80


                  ....*.
gi 24584938   267 DQCYWL 272
Cdd:pfam08445  81 DETYWV 86
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 208-268 1.30e-03

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 37.33  E-value: 1.30e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24584938 208 GYLGALQVKDTHKRRGFGSVVTREIAYRLAVQGHDVMAL-VGPSNKPSSEMFSKLGFQVIDQ 268
Cdd:COG0456  14 AEIEDLAVDPEYRGRGIGRALLEAALERARERGARRLRLeVREDNEAAIALYEKLGFEEVGE 75
 
Name Accession Description Interval E-value
FR47 pfam08445
FR47-like protein; The members of this family are similar to the C-terminal region of the D. ...
 187-272 4.99e-39

FR47-like protein; The members of this family are similar to the C-terminal region of the D. melanogaster hypothetical protein FR47. This protein has been found to consist of two N-acyltransferase-like domains swapped with the C-terminal strands.


Pssm-ID: 117022 [Multi-domain]  Cd Length: 86  Bit Score: 131.68  E-value: 4.99e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584938   187 SVGLYQEDTQELVAWCIRLQGGYLGALQVKDTHKRRGFGSVVTREIAYRLAVQGHDVMALVGPSNKPSSEMFSKLGFQVI 266
Cdd:pfam08445   1 VLGIYRGDTGELAAWCLRLPGGELGALQTLPEHRRRGLGSRLVAALARGIAERGITPFAVVVAGNTPSRRLYEKLGFRKI 80


                  ....*.
gi 24584938   267 DQCYWL 272
Cdd:pfam08445  81 DETYWV 86
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 208-268 1.30e-03

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 37.33  E-value: 1.30e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24584938 208 GYLGALQVKDTHKRRGFGSVVTREIAYRLAVQGHDVMAL-VGPSNKPSSEMFSKLGFQVIDQ 268
Cdd:COG0456  14 AEIEDLAVDPEYRGRGIGRALLEAALERARERGARRLRLeVREDNEAAIALYEKLGFEEVGE 75
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
158-268 5.02e-03

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 36.60  E-value: 5.02e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584938 158 ADAP----LVNAEWPNHHEGSLFfveRQIRLCVSVGLYQ--EDTQELVA----WCIRLQG----GYLGALQVKDTHKRRG 223
Cdd:COG3153   7 EDAEaiaaLLRAAFGPGREAELV---DRLREDPAAGLSLvaEDDGEIVGhvalSPVDIDGegpaLLLGPLAVDPEYRGQG 83

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*
gi 24584938 224 FGSVVTREIAYRLAVQGHDVMALVGpsNKPSSEMFSKLGFQVIDQ 268
Cdd:COG3153  84 IGRALMRAALEAARERGARAVVLLG--DPSLLPFYERFGFRPAGE 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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