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Conserved domains on  [gi|28574357|ref|NP_609978|]
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Hig-anchoring scaffold protein, isoform A [Drosophila melanogaster]

Protein Classification

beta-2-glycoprotein 1( domain architecture ID 12867689)

beta-2-glycoprotein 1 is a heavily glycosylated plasma membrane-adhesion protein, which plays a role in blood coagulation and removal of apoptotic bodies

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 182-421 1.98e-24

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 104.73  E-value: 1.98e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   182 KPPQIEHARNSALPEQETFDLDSTVQYHCHTGYVTN--GFPRAKCLAidnlASWYGPDiQCEPRSCGQPPDPAYGWHAGE 259
Cdd:PHA02927   26 RPINMKFKNSVETDANANYNIGDTIEYLCLPGYRKQkmGPIYAKCTG----TGWTLFN-QCIKRRCPSPRDIDNGQLDIG 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   260 CYTYGCKITYNCGTGYELVGKHERYCQ--SDGS--WTPkELPTCvlvTSVVCPTPENPKNGKATYTTLAYN--SVVSYEC 333
Cdd:PHA02927  101 GVDFGSSITYSCNSGYQLIGESKSYCElgSTGSmvWNP-EAPIC---ESVKCQSPPSISNGRHNGYEDFYTdgSVVTYSC 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   334 RYGYTLVGESSSRCGADrKWSGTlPTCKEINCGHPGVLyNGWIEN-IEAGTGLGASIIFRCQPEMMINGLGSSVCQIDGR 412
Cdd:PHA02927  177 NSGYSLIGNSGVLCSGG-EWSDP-PTCQIVKCPHPTIS-NGYLSSgFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNT 253


                  ....*....
gi 28574357   413 WRNALPECL 421
Cdd:PHA02927  254 WQPELPKCV 262
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 1487-1642 1.09e-15

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 78.93  E-value: 1.09e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1487 EVGGRAAFSCASGYGLRGPAEAICN--PTGE--WSAPLPTCVEVQCDNPGAPQNGYAQGSAP-YRAGDVVQFNCNPEYMM 1561
Cdd:PHA02927  103 DFGSSITYSCNSGYQLIGESKSYCElgSTGSmvWNPEAPICESVKCQSPPSISNGRHNGYEDfYTDGSVVTYSCNSGYSL 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1562 QGQPIIACQdNARWSGGlPKC-VQACSYPgTVISGRMSS-VKFYYAIGESITFTCDAGLDLRGSKVLKCLKNGKWSSAIP 1639
Cdd:PHA02927  183 IGNSGVLCS-GGEWSDP-PTCqIVKCPHP-TISNGYLSSgFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELP 259


                  ...
gi 28574357  1640 TCV 1642
Cdd:PHA02927  260 KCV 262
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 497-654 1.97e-09

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 60.44  E-value: 1.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   497 CNNGTWSIIPRCVPARCKSmPRPPKHGMVMAPKTEHGMKARFKCKDGFKLVSpegkdvtdphDYVLTCSFGN-----WTG 571
Cdd:PHA02927   70 CTGTGWTLFNQCIKRRCPS-PRDIDNGQLDIGGVDFGSSITYSCNSGYQLIG----------ESKSYCELGStgsmvWNP 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   572 ETPKCDEVFCSFPGYIPNGKvllvgnmglydYRPYVKKIVNNKQIMYDCDKGYVLeVGPPGATCVGGKWRplDLPQCLLG 651
Cdd:PHA02927  139 EAPICESVKCQSPPSISNGR-----------HNGYEDFYTDGSVVTYSCNSGYSL-IGNSGVLCSGGEWS--DPPTCQIV 204


                  ...
gi 28574357   652 QHP 654
Cdd:PHA02927  205 KCP 207
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 121-175 1.26e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 47.07  E-value: 1.26e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 28574357  121 CPELAQPSLGQVTVAGRHF--GARASYACPHGYHVVGLQSRLCQADGNWAGAEPACK 175
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYsyGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 1407-1461 1.41e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 41.29  E-value: 1.41e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 28574357 1407 CPEIPMRRGLIVNTNDTKLS--TRALLSCANGNSLIGASELFCLPSGNWSAPLPVCE 1461
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSygSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 945-1110 4.19e-03

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 40.79  E-value: 4.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   945 CNAGFKLniKGEnATARCIRG-----IWKPETPKCLSAPC-LVPAVEHGQYykvephtkqlsdkpsltplSTYEEIQSN- 1017
Cdd:PHA02927  112 CNSGYQL--IGE-SKSYCELGstgsmVWNPEAPICESVKCqSPPSISNGRH-------------------NGYEDFYTDg 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1018 EFITLECEDGFNIQGSAQLRCAHGSWSVNafSECTSVPCTLPNIPGVIYDGGYRAGLTigHGSSVSVRC----ELSTNAN 1093
Cdd:PHA02927  170 SVVTYSCNSGYSLIGNSGVLCSGGEWSDP--PTCQIVKCPHPTISNGYLSSGFKRSYS--YNDNVDFKCkygyKLSGSSS 245

                         170
                  ....*....|....*..
gi 28574357  1094 PiemSCHKGILTPPSIP 1110
Cdd:PHA02927  246 S---TCSPGNTWQPELP 259
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 182-421 1.98e-24

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 104.73  E-value: 1.98e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   182 KPPQIEHARNSALPEQETFDLDSTVQYHCHTGYVTN--GFPRAKCLAidnlASWYGPDiQCEPRSCGQPPDPAYGWHAGE 259
Cdd:PHA02927   26 RPINMKFKNSVETDANANYNIGDTIEYLCLPGYRKQkmGPIYAKCTG----TGWTLFN-QCIKRRCPSPRDIDNGQLDIG 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   260 CYTYGCKITYNCGTGYELVGKHERYCQ--SDGS--WTPkELPTCvlvTSVVCPTPENPKNGKATYTTLAYN--SVVSYEC 333
Cdd:PHA02927  101 GVDFGSSITYSCNSGYQLIGESKSYCElgSTGSmvWNP-EAPIC---ESVKCQSPPSISNGRHNGYEDFYTdgSVVTYSC 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   334 RYGYTLVGESSSRCGADrKWSGTlPTCKEINCGHPGVLyNGWIEN-IEAGTGLGASIIFRCQPEMMINGLGSSVCQIDGR 412
Cdd:PHA02927  177 NSGYSLIGNSGVLCSGG-EWSDP-PTCQIVKCPHPTIS-NGYLSSgFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNT 253


                  ....*....
gi 28574357   413 WRNALPECL 421
Cdd:PHA02927  254 WQPELPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 1487-1642 1.09e-15

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 78.93  E-value: 1.09e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1487 EVGGRAAFSCASGYGLRGPAEAICN--PTGE--WSAPLPTCVEVQCDNPGAPQNGYAQGSAP-YRAGDVVQFNCNPEYMM 1561
Cdd:PHA02927  103 DFGSSITYSCNSGYQLIGESKSYCElgSTGSmvWNPEAPICESVKCQSPPSISNGRHNGYEDfYTDGSVVTYSCNSGYSL 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1562 QGQPIIACQdNARWSGGlPKC-VQACSYPgTVISGRMSS-VKFYYAIGESITFTCDAGLDLRGSKVLKCLKNGKWSSAIP 1639
Cdd:PHA02927  183 IGNSGVLCS-GGEWSDP-PTCqIVKCPHP-TISNGYLSSgFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELP 259


                  ...
gi 28574357  1640 TCV 1642
Cdd:PHA02927  260 KCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 307-361 1.29e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 64.02  E-value: 1.29e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 28574357  307 CPTPENPKNGKATY--TTLAYNSVVSYECRYGYTLVGESSSRCGADRKWSGTLPTCK 361
Cdd:cd00033    1 CPPPPVPENGTVTGskGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 307-360 7.02e-12

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 61.77  E-value: 7.02e-12
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 28574357     307 CPTPENPKNGKATY--TTLAYNSVVSYECRYGYTLVGESSSRCGADRKWSGTLPTC 360
Cdd:smart00032    1 CPPPPDIENGTVTSssGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 1586-1642 1.10e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 61.32  E-value: 1.10e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 28574357 1586 CSYPGTVISGRMSSVKFYYAIGESITFTCDAGLDLRGSKVLKCLKNGKWSSAIPTCV 1642
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 1586-1641 2.87e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 60.23  E-value: 2.87e-11
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 28574357    1586 CSYPGTVISGRMSSVKFYYAIGESITFTCDAGLDLRGSKVLKCLKNGKWSSAIPTC 1641
Cdd:smart00032    1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
307-360 1.40e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 58.28  E-value: 1.40e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 28574357    307 CPTPENPKNGKATYTTLAYN--SVVSYECRYGYTLVGESSSRCGADRKWSGTLPTC 360
Cdd:pfam00084    1 CPPPPDIPNGKVSATKNEYNygASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
1586-1641 1.54e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 55.20  E-value: 1.54e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 28574357   1586 CSYPGTVISGRMSSVKFYYAIGESITFTCDAGLDLRGSKVLKCLKNGKWSSAIPTC 1641
Cdd:pfam00084    1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 497-654 1.97e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 60.44  E-value: 1.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   497 CNNGTWSIIPRCVPARCKSmPRPPKHGMVMAPKTEHGMKARFKCKDGFKLVSpegkdvtdphDYVLTCSFGN-----WTG 571
Cdd:PHA02927   70 CTGTGWTLFNQCIKRRCPS-PRDIDNGQLDIGGVDFGSSITYSCNSGYQLIG----------ESKSYCELGStgsmvWNP 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   572 ETPKCDEVFCSFPGYIPNGKvllvgnmglydYRPYVKKIVNNKQIMYDCDKGYVLeVGPPGATCVGGKWRplDLPQCLLG 651
Cdd:PHA02927  139 EAPICESVKCQSPPSISNGR-----------HNGYEDFYTDGSVVTYSCNSGYSL-IGNSGVLCSGGEWS--DPPTCQIV 204


                  ...
gi 28574357   652 QHP 654
Cdd:PHA02927  205 KCP 207
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 121-175 1.26e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 47.07  E-value: 1.26e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 28574357  121 CPELAQPSLGQVTVAGRHF--GARASYACPHGYHVVGLQSRLCQADGNWAGAEPACK 175
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYsyGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 121-174 3.20e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.98  E-value: 3.20e-06
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 28574357     121 CPELAQPSLGQVTVAGR--HFGARASYACPHGYHVVGLQSRLCQADGNWAGAEPAC 174
Cdd:smart00032    1 CPPPPDIENGTVTSSSGtySYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
139-174 5.36e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.49  E-value: 5.36e-05
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 28574357    139 FGARASYACPHGYHVVGLQSRLCQADGNWAGAEPAC 174
Cdd:pfam00084   21 YGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 1407-1461 1.41e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 41.29  E-value: 1.41e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 28574357 1407 CPEIPMRRGLIVNTNDTKLS--TRALLSCANGNSLIGASELFCLPSGNWSAPLPVCE 1461
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSygSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
515-576 4.67e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 39.79  E-value: 4.67e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28574357    515 SMPRPPKHGMVMAPKTEH--GMKARFKCKDGFKLVSPEgkdvtdphdyVLTCSF-GNWTGETPKC 576
Cdd:pfam00084    2 PPPPDIPNGKVSATKNEYnyGASVSYECDPGYRLVGSP----------TITCQEdGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 517-576 5.63e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 39.43  E-value: 5.63e-04
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28574357     517 PRPPKHGMVMAPKT--EHGMKARFKCKDGFKLVSPEgkdvtdphdyVLTC-SFGNWTGETPKC 576
Cdd:smart00032    4 PPDIENGTVTSSSGtySYGDTVTYSCDPGYTLIGSS----------TITClENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 1407-1460 6.40e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 39.43  E-value: 6.40e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 28574357    1407 CPEIPM-RRGLIVNTNDT-KLSTRALLSCANGNSLIGASELFCLPSGNWSAPLPVC 1460
Cdd:smart00032    1 CPPPPDiENGTVTSSSGTySYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 517-576 8.95e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 38.98  E-value: 8.95e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28574357  517 PRPPKHGMV--MAPKTEHGMKARFKCKDGFKLVSPEgkdvtdphdyVLTC-SFGNWTGETPKC 576
Cdd:cd00033    4 PPVPENGTVtgSKGSYSYGSTVTYSCNEGYTLVGSS----------TITCtENGGWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 945-1110 4.19e-03

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 40.79  E-value: 4.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   945 CNAGFKLniKGEnATARCIRG-----IWKPETPKCLSAPC-LVPAVEHGQYykvephtkqlsdkpsltplSTYEEIQSN- 1017
Cdd:PHA02927  112 CNSGYQL--IGE-SKSYCELGstgsmVWNPEAPICESVKCqSPPSISNGRH-------------------NGYEDFYTDg 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1018 EFITLECEDGFNIQGSAQLRCAHGSWSVNafSECTSVPCTLPNIPGVIYDGGYRAGLTigHGSSVSVRC----ELSTNAN 1093
Cdd:PHA02927  170 SVVTYSCNSGYSLIGNSGVLCSGGEWSDP--PTCQIVKCPHPTISNGYLSSGFKRSYS--YNDNVDFKCkygyKLSGSSS 245

                         170
                  ....*....|....*..
gi 28574357  1094 PiemSCHKGILTPPSIP 1110
Cdd:PHA02927  246 S---TCSPGNTWQPELP 259
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 182-421 1.98e-24

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 104.73  E-value: 1.98e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   182 KPPQIEHARNSALPEQETFDLDSTVQYHCHTGYVTN--GFPRAKCLAidnlASWYGPDiQCEPRSCGQPPDPAYGWHAGE 259
Cdd:PHA02927   26 RPINMKFKNSVETDANANYNIGDTIEYLCLPGYRKQkmGPIYAKCTG----TGWTLFN-QCIKRRCPSPRDIDNGQLDIG 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   260 CYTYGCKITYNCGTGYELVGKHERYCQ--SDGS--WTPkELPTCvlvTSVVCPTPENPKNGKATYTTLAYN--SVVSYEC 333
Cdd:PHA02927  101 GVDFGSSITYSCNSGYQLIGESKSYCElgSTGSmvWNP-EAPIC---ESVKCQSPPSISNGRHNGYEDFYTdgSVVTYSC 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   334 RYGYTLVGESSSRCGADrKWSGTlPTCKEINCGHPGVLyNGWIEN-IEAGTGLGASIIFRCQPEMMINGLGSSVCQIDGR 412
Cdd:PHA02927  177 NSGYSLIGNSGVLCSGG-EWSDP-PTCQIVKCPHPTIS-NGYLSSgFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNT 253


                  ....*....
gi 28574357   413 WRNALPECL 421
Cdd:PHA02927  254 WQPELPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 114-360 9.86e-21

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 93.95  E-value: 9.86e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   114 CIKPDRECPELAQPSLGQVTVAGRHFGARASYACPHGYHVVGLQSRLCQADGN-WAGAEPACKQNiyCLKPPQIEHARns 192
Cdd:PHA02927   21 CTIPSRPINMKFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTgWTLFNQCIKRR--CPSPRDIDNGQ-- 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   193 alPEQETFDLDSTVQYHCHTGYVTNGFPRAKC-LAIDNLASWYGPDIQCEPRSCGQPPDPAYGWHAG--ECYTYGCKITY 269
Cdd:PHA02927   97 --LDIGGVDFGSSITYSCNSGYQLIGESKSYCeLGSTGSMVWNPEAPICESVKCQSPPSISNGRHNGyeDFYTDGSVVTY 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   270 NCGTGYELVGKHERYCqSDGSWTpkELPTCVLVTsvvCPTPE--NPKNGKATYTTLAYNSVVSYECRYGYTLVGESSSRC 347
Cdd:PHA02927  175 SCNSGYSLIGNSGVLC-SGGEWS--DPPTCQIVK---CPHPTisNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTC 248

                         250
                  ....*....|...
gi 28574357   348 GADRKWSGTLPTC 360
Cdd:PHA02927  249 SPGNTWQPELPKC 261
PHA02639 PHA02639
EEV host range protein; Provisional
 176-360 1.00e-17

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 85.87  E-value: 1.00e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   176 QNIYCLKPPQIEHARNSALpeQETFDLDSTVQYHCHTGYVTNGFPRAKCLAIDNLASWYGPDIQCEPRSCGQPPDPAYG- 254
Cdd:PHA02639   18 KSIYCDKPDDISNGFITEL--MEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAIWSNKAPFCMLKECNDPPSIINGk 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   255 -WHAGECYTYGCKITYNC----GTGYELVGKHERYCQSDGSWTPkELPTCVLVTSVVCPTPENPKNGKATYTTLAYNSVV 329
Cdd:PHA02639   96 iYNKREMYKVGDEIYYVCnehkGVQYSLVGNEKITCIQDKSWKP-DPPICKMINCRFPALQNGYINGIPSNKKFYYKTRV 174

                         170       180       190
                  ....*....|....*....|....*....|.
gi 28574357   330 SYECRYGYTLVGESSSRCGADRKWSGTLPTC 360
Cdd:PHA02639  175 GFSCKSGFDLVGEKYSTCNINATWFPSIPTC 205
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 1487-1642 1.09e-15

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 78.93  E-value: 1.09e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1487 EVGGRAAFSCASGYGLRGPAEAICN--PTGE--WSAPLPTCVEVQCDNPGAPQNGYAQGSAP-YRAGDVVQFNCNPEYMM 1561
Cdd:PHA02927  103 DFGSSITYSCNSGYQLIGESKSYCElgSTGSmvWNPEAPICESVKCQSPPSISNGRHNGYEDfYTDGSVVTYSCNSGYSL 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1562 QGQPIIACQdNARWSGGlPKC-VQACSYPgTVISGRMSS-VKFYYAIGESITFTCDAGLDLRGSKVLKCLKNGKWSSAIP 1639
Cdd:PHA02927  183 IGNSGVLCS-GGEWSDP-PTCqIVKCPHP-TISNGYLSSgFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELP 259


                  ...
gi 28574357  1640 TCV 1642
Cdd:PHA02927  260 KCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 1432-1584 2.96e-15

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 77.77  E-value: 2.96e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1432 SCANGNSLIGASELFC----LPSGNWSAPLPVCESVECGDIPlgMGSNASSPRVSVLSREvGGRAAFSCASGYGLRGPAE 1507
Cdd:PHA02927  111 SCNSGYQLIGESKSYCelgsTGSMVWNPEAPICESVKCQSPP--SISNGRHNGYEDFYTD-GSVVTYSCNSGYSLIGNSG 187

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 28574357  1508 AICNpTGEWSAPlPTCVEVQCDNPgAPQNGYAQG--SAPYRAGDVVQFNCNPEYMMQGQPIIACQDNARWSGGLPKCVQ 1584
Cdd:PHA02927  188 VLCS-GGEWSDP-PTCQIVKCPHP-TISNGYLSSgfKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKCVR 263
PHA02639 PHA02639
EEV host range protein; Provisional
 1487-1645 6.05e-15

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 77.40  E-value: 6.05e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1487 EVGGRAAFSCASGYGLRGPAEAIC---NPTGEWSAPLPTCVEVQCDNPGAPQNGYAQGSAP-YRAGDVVQFNCNP----E 1558
Cdd:PHA02639   41 EIGKLIEYTCNTDYALIGDRFRTCikdKNNAIWSNKAPFCMLKECNDPPSIINGKIYNKREmYKVGDEIYYVCNEhkgvQ 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1559 YMMQGQPIIACQDNARWSGGLPKC-VQACSYPGT---VISGRMSSVKFYYAIgeSITFTCDAGLDLRGSKVLKCLKNGKW 1634
Cdd:PHA02639  121 YSLVGNEKITCIQDKSWKPDPPICkMINCRFPALqngYINGIPSNKKFYYKT--RVGFSCKSGFDLVGEKYSTCNINATW 198

                         170
                  ....*....|.
gi 28574357  1635 SSAIPTCVTNE 1645
Cdd:PHA02639  199 FPSIPTCVRNK 209
PHA02639 PHA02639
EEV host range protein; Provisional
 245-421 7.52e-13

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 71.23  E-value: 7.52e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   245 CGQPPDPAYGW--HAGECYTYGCKITYNCGTGYELVGKHERYCQSDGS---WTPKElPTCVLVTsvvCPTPENPKNGKAT 319
Cdd:PHA02639   22 CDKPDDISNGFitELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNnaiWSNKA-PFCMLKE---CNDPPSIINGKIY 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   320 YTTLAYN--SVVSYECR----YGYTLVGESSSRCGADRKWSGTLPTCKEINCGHPGvLYNGWIENIEAGTGL--GASIIF 391
Cdd:PHA02639   98 NKREMYKvgDEIYYVCNehkgVQYSLVGNEKITCIQDKSWKPDPPICKMINCRFPA-LQNGYINGIPSNKKFyyKTRVGF 176

                         170       180       190
                  ....*....|....*....|....*....|
gi 28574357   392 RCQPEMMINGLGSSVCQIDGRWRNALPECL 421
Cdd:PHA02639  177 SCKSGFDLVGEKYSTCNINATWFPSIPTCV 206
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 307-361 1.29e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 64.02  E-value: 1.29e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 28574357  307 CPTPENPKNGKATY--TTLAYNSVVSYECRYGYTLVGESSSRCGADRKWSGTLPTCK 361
Cdd:cd00033    1 CPPPPVPENGTVTGskGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
PHA02817 PHA02817
EEV Host range protein; Provisional
 240-373 1.72e-12

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 68.81  E-value: 1.72e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   240 CEPRSCGQPPDPAYG--WHAGECYTYGCKITYNCGTG-----YELVGKHERYCQSDGSWTPkELPTCVLVTSVVCPTPEN 312
Cdd:PHA02817   19 CDLNKCCYPPSIKNGyiYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNK-EFPVCKIIRCRFPALQNG 97

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 28574357   313 PKNGKATYTTLAYNSVVSYECRYGYTLVGESSSRCGADRKWSGTLPTCKEINCGHPGVLYN 373
Cdd:PHA02817   98 FVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPICSRDNITYNKIYIN 158
PHA02831 PHA02831
EEV host range protein; Provisional
 266-421 2.88e-12

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 68.87  E-value: 2.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   266 KITYNCGTGYELVGKherYCqSDGSWTPKELptCVLVTSvvCPTP-----ENPKNGKATYTtlaYNSVVSYECRYG---- 336
Cdd:PHA02831   45 NLEYKCNNNFDKVFV---TC-NNGSWSTKNM--CIGKRN--CKDPvtilnGYIKNKKDQYS---FGDSVTYACKVNklek 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   337 YTLVGESSSRCgADRKWSGTLPTCKEINCGHPGvLYNGWIENIEAGTGLGASIIFRCQPEMMINGLGSSVCQIDGRWRNA 416
Cdd:PHA02831  114 YSIVGNETVKC-INKQWVPKYPVCKLIRCKYPA-LQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPG 191


                  ....*
gi 28574357   417 LPECL 421
Cdd:PHA02831  192 IPKCV 196
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 307-360 7.02e-12

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 61.77  E-value: 7.02e-12
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 28574357     307 CPTPENPKNGKATY--TTLAYNSVVSYECRYGYTLVGESSSRCGADRKWSGTLPTC 360
Cdd:smart00032    1 CPPPPDIENGTVTSssGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 1586-1642 1.10e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 61.32  E-value: 1.10e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 28574357 1586 CSYPGTVISGRMSSVKFYYAIGESITFTCDAGLDLRGSKVLKCLKNGKWSSAIPTCV 1642
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 1586-1641 2.87e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 60.23  E-value: 2.87e-11
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 28574357    1586 CSYPGTVISGRMSSVKFYYAIGESITFTCDAGLDLRGSKVLKCLKNGKWSSAIPTC 1641
Cdd:smart00032    1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 1528-1583 1.37e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 58.24  E-value: 1.37e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 28574357 1528 CDNPGAPQNGYAQGS-APYRAGDVVQFNCNPEYMMQGQPIIACQDNARWSGGLPKCV 1583
Cdd:cd00033    1 CPPPPVPENGTVTGSkGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
307-360 1.40e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 58.28  E-value: 1.40e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 28574357    307 CPTPENPKNGKATYTTLAYN--SVVSYECRYGYTLVGESSSRCGADRKWSGTLPTC 360
Cdd:pfam00084    1 CPPPPDIPNGKVSATKNEYNygASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 1528-1582 3.51e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.15  E-value: 3.51e-10
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 28574357    1528 CDNPGAPQNGYAQGS-APYRAGDVVQFNCNPEYMMQGQPIIACQDNARWSGGLPKC 1582
Cdd:smart00032    1 CPPPPDIENGTVTSSsGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
1586-1641 1.54e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 55.20  E-value: 1.54e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 28574357   1586 CSYPGTVISGRMSSVKFYYAIGESITFTCDAGLDLRGSKVLKCLKNGKWSSAIPTC 1641
Cdd:pfam00084    1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 245-300 1.82e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 55.16  E-value: 1.82e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 28574357  245 CGQPPDPAYGWHAGEC--YTYGCKITYNCGTGYELVGKHERYCQSDGSWTPkELPTCV 300
Cdd:cd00033    1 CPPPPVPENGTVTGSKgsYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSP-PPPTCE 57
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 497-654 1.97e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 60.44  E-value: 1.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   497 CNNGTWSIIPRCVPARCKSmPRPPKHGMVMAPKTEHGMKARFKCKDGFKLVSpegkdvtdphDYVLTCSFGN-----WTG 571
Cdd:PHA02927   70 CTGTGWTLFNQCIKRRCPS-PRDIDNGQLDIGGVDFGSSITYSCNSGYQLIG----------ESKSYCELGStgsmvWNP 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   572 ETPKCDEVFCSFPGYIPNGKvllvgnmglydYRPYVKKIVNNKQIMYDCDKGYVLeVGPPGATCVGGKWRplDLPQCLLG 651
Cdd:PHA02927  139 EAPICESVKCQSPPSISNGR-----------HNGYEDFYTDGSVVTYSCNSGYSL-IGNSGVLCSGGEWS--DPPTCQIV 204


                  ...
gi 28574357   652 QHP 654
Cdd:PHA02927  205 KCP 207
Sushi pfam00084
Sushi repeat (SCR repeat);
1528-1582 2.10e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 54.81  E-value: 2.10e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 28574357   1528 CDNPGAPQNGYAQGSAP-YRAGDVVQFNCNPEYMMQGQPIIACQDNARWSGGLPKC 1582
Cdd:pfam00084    1 CPPPPDIPNGKVSATKNeYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 196-360 2.89e-09

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 60.01  E-value: 2.89e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   196 EQETFDLDSTVQYHCHTGYvtngfprAKCLAIDNLASWYGPDIQCEPRSCGQPPDPAYGW--HAGECYTYGCKITYNCGT 273
Cdd:PHA02831   36 ENKVYEENENLEYKCNNNF-------DKVFVTCNNGSWSTKNMCIGKRNCKDPVTILNGYikNKKDQYSFGDSVTYACKV 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   274 G----YELVGKHERYCqSDGSWTPKElPTCVLVTsvvCPTPEnPKNG--KATYTTLAYNSVVSYECRYGYTLVGESSSRC 347
Cdd:PHA02831  109 NklekYSIVGNETVKC-INKQWVPKY-PVCKLIR---CKYPA-LQNGflNVFEKKFYYGDIVNFKCKKGFILLGSSVSTC 182

                         170
                  ....*....|...
gi 28574357   348 GADRKWSGTLPTC 360
Cdd:PHA02831  183 DINSIWYPGIPKC 195
PHA02831 PHA02831
EEV host range protein; Provisional
 1494-1645 8.60e-09

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 58.47  E-value: 8.60e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1494 FSCASGYGlrgPAEAICNpTGEWSAPLPTCVEVQCDNPGAPQNGYAQGSA-PYRAGDVVQFNCN----PEYMMQGQPIIA 1568
Cdd:PHA02831   48 YKCNNNFD---KVFVTCN-NGSWSTKNMCIGKRNCKDPVTILNGYIKNKKdQYSFGDSVTYACKvnklEKYSIVGNETVK 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1569 CQDnARWSGGLPKC-VQACSYPGtVISGRMSSV--KFYYaiGESITFTCDAGLDLRGSKVLKCLKNGKWSSAIPTCVTNE 1645
Cdd:PHA02831  124 CIN-KQWVPKYPVCkLIRCKYPA-LQNGFLNVFekKFYY--GDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCVKDK 199
PHA02817 PHA02817
EEV Host range protein; Provisional
 1523-1645 9.43e-09

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 57.64  E-value: 9.43e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1523 CVEVQCDNPGAPQNGYA-QGSAPYRAGDVVQFNCNPE-----YMMQGQPIIACQDNARWSGGLPKC-VQACSYPGT---V 1592
Cdd:PHA02817   19 CDLNKCCYPPSIKNGYIyNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCkIIRCRFPALqngF 98

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 28574357  1593 ISGRMSSVKFYYAigESITFTCDAGLDLRGSKVLKCLKNGKWSSAIPTCVTNE 1645
Cdd:PHA02817   99 VNGIPDSKKFYYE--SEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPICSRDN 149
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 142-364 1.41e-08

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 58.56  E-value: 1.41e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   142 RASYACPHGYHVVGLQSrLCQADgNWAGAEPaCKQniYCLKPPQIEHARNSALpeqetFDLDSTVQYHCH--TGYVtngf 219
Cdd:PHA02954   43 KVTFTCDSGYYSLDPNA-VCETD-KWKYENP-CKK--MCTVSDYVSELYDKPL-----YEVNSTITLICKdeTKYF---- 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   220 praKCLAIDNLASWYG----PDIQCEPR-----SCgQPpdpaygwhAGECYTYGCKITYNCGTGYELVGKHERYCQSDgS 290
Cdd:PHA02954  109 ---RCEEKNGNTSWNDtvtcPNAECQPLqlehgSC-QP--------VKEKYSFGEHITINCDVGYEVIGASYISCTAN-S 175

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 28574357   291 WTPkeLPTCvlvtSVVCPTPeNPKNGKATYTTLAYNSVVSYECRYGYTLVGESSSRCgADRKWSGTLPTCKEIN 364
Cdd:PHA02954  176 WNV--IPSC----QQKCDIP-SLSNGLISGSTFSIGGVIHLSCKSGFTLTGSPSSTC-IDGKWNPVLPICVRSN 241
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 245-299 1.92e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.14  E-value: 1.92e-08
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 28574357     245 CGQPPDPAYGWH--AGECYTYGCKITYNCGTGYELVGKHERYCQSDGSWTPkELPTC 299
Cdd:smart00032    1 CPPPPDIENGTVtsSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSP-PPPTC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 307-420 2.18e-08

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 56.49  E-value: 2.18e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   307 CPTPENPKNGKATYTTLAYN--SVVSYECRYG-----YTLVGESSSRCGADRKWSGTLPTCKEINCGHPGvLYNGWIENI 379
Cdd:PHA02817   24 CCYPPSIKNGYIYNKKTEYNigSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCKIIRCRFPA-LQNGFVNGI 102

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 28574357   380 EAGTGL--GASIIFRCQPEMMINGLGSSVCQIDGRWRNALPEC 420
Cdd:PHA02817  103 PDSKKFyyESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPIC 145
Sushi pfam00084
Sushi repeat (SCR repeat);
245-299 7.13e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.58  E-value: 7.13e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 28574357    245 CGQPPDPAYGW--HAGECYTYGCKITYNCGTGYELVGKHERYCQSDGSWTPKElPTC 299
Cdd:pfam00084    1 CPPPPDIPNGKvsATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPF-PEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 1432-1584 3.38e-07

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 53.90  E-value: 3.38e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1432 SCANGNSLIGASELFCLPSGN---WSAPLPVCESVECGDIPLGMGSNASSPRVSVlsrEVGGRAAFSC----ASGYGLRG 1504
Cdd:PHA02639   49 TCNTDYALIGDRFRTCIKDKNnaiWSNKAPFCMLKECNDPPSIINGKIYNKREMY---KVGDEIYYVCnehkGVQYSLVG 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1505 PAEAICNPTGEWSAPLPTCVEVQCDNPgAPQNGYAQG---SAPYRAGDVVQFNCNPEYMMQGQPIIACQDNARWSGGLPK 1581
Cdd:PHA02639  126 NEKITCIQDKSWKPDPPICKMINCRFP-ALQNGYINGipsNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPT 204


                  ...
gi 28574357  1582 CVQ 1584
Cdd:PHA02639  205 CVR 207
PHA02817 PHA02817
EEV Host range protein; Provisional
 1500-1584 6.05e-07

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 52.25  E-value: 6.05e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1500 YGLRGPAEAICNPTGEWSAPLPTCVEVQCDNPgAPQNGYAQG---SAPYRAGDVVQFNCNPEYMMQGQPIIACQDNARWS 1576
Cdd:PHA02817   61 YTLVGEKNIICEKDGKWNKEFPVCKIIRCRFP-ALQNGFVNGipdSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWI 139


                  ....*...
gi 28574357  1577 GGLPKCVQ 1584
Cdd:PHA02817  140 PKVPICSR 147
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 121-175 1.26e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 47.07  E-value: 1.26e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 28574357  121 CPELAQPSLGQVTVAGRHF--GARASYACPHGYHVVGLQSRLCQADGNWAGAEPACK 175
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYsyGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 1487-1524 1.38e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 47.07  E-value: 1.38e-06
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 28574357 1487 EVGGRAAFSCASGYGLRGPAEAICNPTGEWSAPLPTCV 1524
Cdd:cd00033   20 SYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 1522-1645 1.39e-06

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 52.40  E-value: 1.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1522 TCVEVQCDNPGAPQNGYAQGSAPYRAGDVVQFNCNPEYMMQGQPIIACQDNArWSGgLPKCVQACSYPgTVISGRMSSVK 1601
Cdd:PHA02954  124 TCPNAECQPLQLEHGSCQPVKEKYSFGEHITINCDVGYEVIGASYISCTANS-WNV-IPSCQQKCDIP-SLSNGLISGST 200

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 28574357  1602 FyyAIGESITFTCDAGLDLRGSKVLKCLkNGKWSSAIPTCV-TNE 1645
Cdd:PHA02954  201 F--SIGGVIHLSCKSGFTLTGSPSSTCI-DGKWNPVLPICVrSNE 242
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 121-174 3.20e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.98  E-value: 3.20e-06
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 28574357     121 CPELAQPSLGQVTVAGR--HFGARASYACPHGYHVVGLQSRLCQADGNWAGAEPAC 174
Cdd:smart00032    1 CPPPPDIENGTVTSSSGtySYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 365-420 5.18e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.21  E-value: 5.18e-06
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 28574357     365 CGHPGVLYNGWIENIEAGTGLGASIIFRCQPEMMINGLGSSVCQIDGRWRNALPEC 420
Cdd:smart00032    1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 365-420 9.17e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 44.76  E-value: 9.17e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 28574357  365 CGHPGVLYNGWIENIEAGTGLGASIIFRCQPEMMINGLGSSVCQIDGRWRNALPEC 420
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 1487-1523 1.29e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 44.05  E-value: 1.29e-05
                            10        20        30
                    ....*....|....*....|....*....|....*..
gi 28574357    1487 EVGGRAAFSCASGYGLRGPAEAICNPTGEWSAPLPTC 1523
Cdd:smart00032   20 SYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
139-174 5.36e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.49  E-value: 5.36e-05
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 28574357    139 FGARASYACPHGYHVVGLQSRLCQADGNWAGAEPAC 174
Cdd:pfam00084   21 YGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 477-649 1.17e-04

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 45.75  E-value: 1.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   477 LEVKCdeNYEFPVSLLsppTCNNGTWSIIPRCVPAR-CKSmPRPPKHGMVMAPKTEH--GMKARFKCK----DGFKLVSP 549
Cdd:PHA02831   46 LEYKC--NNNFDKVFV---TCNNGSWSTKNMCIGKRnCKD-PVTILNGYIKNKKDQYsfGDSVTYACKvnklEKYSIVGN 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   550 EgkdvtdphdyVLTCSFGNWTGETPKCDEVFCSFPGyipngkvLLVGNMGLYDYRPYVKKIVNNKqimydCDKGYVLeVG 629
Cdd:PHA02831  120 E----------TVKCINKQWVPKYPVCKLIRCKYPA-------LQNGFLNVFEKKFYYGDIVNFK-----CKKGFIL-LG 176

                         170       180
                  ....*....|....*....|.
gi 28574357   630 PPGATC-VGGKWRPlDLPQCL 649
Cdd:PHA02831  177 SSVSTCdINSIWYP-GIPKCV 196
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 1407-1461 1.41e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 41.29  E-value: 1.41e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 28574357 1407 CPEIPMRRGLIVNTNDTKLS--TRALLSCANGNSLIGASELFCLPSGNWSAPLPVCE 1461
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSygSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 180-241 1.48e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 41.29  E-value: 1.48e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28574357  180 CLKPPQIEHARNSalPEQETFDLDSTVQYHCHTGYVTNGFPRAKCLAiDNlaSWYGPDIQCE 241
Cdd:cd00033    1 CPPPPVPENGTVT--GSKGSYSYGSTVTYSCNEGYTLVGSSTITCTE-NG--GWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
515-576 4.67e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 39.79  E-value: 4.67e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28574357    515 SMPRPPKHGMVMAPKTEH--GMKARFKCKDGFKLVSPEgkdvtdphdyVLTCSF-GNWTGETPKC 576
Cdd:pfam00084    2 PPPPDIPNGKVSATKNEYnyGASVSYECDPGYRLVGSP----------TITCQEdGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 180-240 5.36e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 39.43  E-value: 5.36e-04
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 28574357     180 CLKPPQIEHARnsALPEQETFDLDSTVQYHCHTGYVTNGFPRAKCLaidNLASWYGPDIQC 240
Cdd:smart00032    1 CPPPPDIENGT--VTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCL---ENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 517-576 5.63e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 39.43  E-value: 5.63e-04
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28574357     517 PRPPKHGMVMAPKT--EHGMKARFKCKDGFKLVSPEgkdvtdphdyVLTC-SFGNWTGETPKC 576
Cdd:smart00032    4 PPDIENGTVTSSSGtySYGDTVTYSCDPGYTLIGSS----------TITClENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 1407-1460 6.40e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 39.43  E-value: 6.40e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 28574357    1407 CPEIPM-RRGLIVNTNDT-KLSTRALLSCANGNSLIGASELFCLPSGNWSAPLPVC 1460
Cdd:smart00032    1 CPPPPDiENGTVTSSSGTySYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 517-576 8.95e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 38.98  E-value: 8.95e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28574357  517 PRPPKHGMV--MAPKTEHGMKARFKCKDGFKLVSPEgkdvtdphdyVLTC-SFGNWTGETPKC 576
Cdd:cd00033    4 PPVPENGTVtgSKGSYSYGSTVTYSCNEGYTLVGSS----------TITCtENGGWSPPPPTC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 1438-1525 1.42e-03

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 42.24  E-value: 1.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1438 SLIGASELFCLPSGNWSAPLPVCESVECGDIPLGMGSNASSPRVSVLSREvgGRAAFSCASGYGLRGPAEAICNPTGEWS 1517
Cdd:PHA02817   62 TLVGEKNIICEKDGKWNKEFPVCKIIRCRFPALQNGFVNGIPDSKKFYYE--SEVSFSCKPGFVLIGTKYSVCGINSSWI 139


                  ....*...
gi 28574357  1518 APLPTCVE 1525
Cdd:PHA02817  140 PKVPICSR 147
Sushi pfam00084
Sushi repeat (SCR repeat);
180-240 1.64e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 38.25  E-value: 1.64e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 28574357    180 CLKPPQIEHARNSAlpEQETFDLDSTVQYHCHTGYVTNGFPRAKCLaiDNLaSWYGPDIQC 240
Cdd:pfam00084    1 CPPPPDIPNGKVSA--TKNEYNYGASVSYECDPGYRLVGSPTITCQ--EDG-TWSPPFPEC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 140-238 2.21e-03

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 41.46  E-value: 2.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   140 GARASYACPHG-----YHVVGLQSRLCQADGNWAGAEPACKQnIYClKPPQIEHARNSALPEQETFDLDSTVQYHCHTGY 214
Cdd:PHA02817   45 GSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCKI-IRC-RFPALQNGFVNGIPDSKKFYYESEVSFSCKPGF 122

                          90       100
                  ....*....|....*....|....
gi 28574357   215 VTNGFPRAKClaidNLASWYGPDI 238
Cdd:PHA02817  123 VLIGTKYSVC----GINSSWIPKV 142
Sushi pfam00084
Sushi repeat (SCR repeat);
1487-1523 3.31e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 37.48  E-value: 3.31e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 28574357   1487 EVGGRAAFSCASGYGLRGPAEAICNPTGEWSAPLPTC 1523
Cdd:pfam00084   20 NYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 945-1110 4.19e-03

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 40.79  E-value: 4.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357   945 CNAGFKLniKGEnATARCIRG-----IWKPETPKCLSAPC-LVPAVEHGQYykvephtkqlsdkpsltplSTYEEIQSN- 1017
Cdd:PHA02927  112 CNSGYQL--IGE-SKSYCELGstgsmVWNPEAPICESVKCqSPPSISNGRH-------------------NGYEDFYTDg 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28574357  1018 EFITLECEDGFNIQGSAQLRCAHGSWSVNafSECTSVPCTLPNIPGVIYDGGYRAGLTigHGSSVSVRC----ELSTNAN 1093
Cdd:PHA02927  170 SVVTYSCNSGYSLIGNSGVLCSGGEWSDP--PTCQIVKCPHPTISNGYLSSGFKRSYS--YNDNVDFKCkygyKLSGSSS 245

                         170
                  ....*....|....*..
gi 28574357  1094 PiemSCHKGILTPPSIP 1110
Cdd:PHA02927  246 S---TCSPGNTWQPELP 259
Sushi pfam00084
Sushi repeat (SCR repeat);
365-420 4.45e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 37.09  E-value: 4.45e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 28574357    365 CGHPGVLYNGWIENIEAGTGLGASIIFRCQPEMMINGLGSSVCQIDGRWRNALPEC 420
Cdd:pfam00084    1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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