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Conserved domains on  [gi|24586048|ref|NP_610227|]
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ribonuclease P/MRP subunit p25, isoform C [Drosophila melanogaster]

Protein Classification

ribonuclease P subunit p25 family protein( domain architecture ID 10487281)

ribonuclease P (RNase P) protein subunit p25 family protein similar to Homo sapiens ribonuclease P protein subunit p25 and Saccharomyces cerevisiae ribonucleases P/MRP protein subunit POP6, is an AlbA family DNA/RNA-binding protein that belongs to a family of small basic dimeric nucleic acid-binding proteins which may be regulated via acetylation/deacetylation

CATH:  3.30.110.20
Gene Ontology:  GO:0003676
PubMed:  26900088
SCOP:  3000507

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Alba pfam01918
Alba; Alba is a novel chromosomal protein that coats archaeal DNA without compacting it.
 34-97 3.28e-13

Alba; Alba is a novel chromosomal protein that coats archaeal DNA without compacting it.


:

Pssm-ID: 426509  Cd Length: 66  Bit Score: 61.84  E-value: 3.28e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24586048    34 WMHVKGGTKVSNVIEFAQEALNKGeHRCVVWSGSGGGVVKTISCAEVLKRSHP--LYQVTRMAYTS 97
Cdd:pfam01918   2 VIRVSKNKPIMNYVLRALKLLNGG-ADEVVIKALGRAISKAVSVAEILKRRFLkgLHQINKITSSS 66
PHA03309 super family cl29689
transcriptional regulator ICP4; Provisional
 149-206 4.42e-03

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03309:

Pssm-ID: 165564 [Multi-domain]  Cd Length: 2033  Bit Score: 37.53  E-value: 4.42e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 24586048   149 GGGAQQQPHPRSQPRHQQQPHKPGAGRGGRPNKRTRPGRNKPGQQPEKPAAEENLPAS 206
Cdd:PHA03309 1561 GGKRPRSSSSSSSASHDRSPSSSSRRRDGRPSSRRRPSRRMSARPPSRPPAAVILRAS 1618
 
Name Accession Description Interval E-value
Alba pfam01918
Alba; Alba is a novel chromosomal protein that coats archaeal DNA without compacting it.
 34-97 3.28e-13

Alba; Alba is a novel chromosomal protein that coats archaeal DNA without compacting it.


Pssm-ID: 426509  Cd Length: 66  Bit Score: 61.84  E-value: 3.28e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24586048    34 WMHVKGGTKVSNVIEFAQEALNKGeHRCVVWSGSGGGVVKTISCAEVLKRSHP--LYQVTRMAYTS 97
Cdd:pfam01918   2 VIRVSKNKPIMNYVLRALKLLNGG-ADEVVIKALGRAISKAVSVAEILKRRFLkgLHQINKITSSS 66
PHA03309 PHA03309
transcriptional regulator ICP4; Provisional
 149-206 4.42e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 165564 [Multi-domain]  Cd Length: 2033  Bit Score: 37.53  E-value: 4.42e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 24586048   149 GGGAQQQPHPRSQPRHQQQPHKPGAGRGGRPNKRTRPGRNKPGQQPEKPAAEENLPAS 206
Cdd:PHA03309 1561 GGKRPRSSSSSSSASHDRSPSSSSRRRDGRPSSRRRPSRRMSARPPSRPPAAVILRAS 1618
 
Name Accession Description Interval E-value
Alba pfam01918
Alba; Alba is a novel chromosomal protein that coats archaeal DNA without compacting it.
 34-97 3.28e-13

Alba; Alba is a novel chromosomal protein that coats archaeal DNA without compacting it.


Pssm-ID: 426509  Cd Length: 66  Bit Score: 61.84  E-value: 3.28e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24586048    34 WMHVKGGTKVSNVIEFAQEALNKGeHRCVVWSGSGGGVVKTISCAEVLKRSHP--LYQVTRMAYTS 97
Cdd:pfam01918   2 VIRVSKNKPIMNYVLRALKLLNGG-ADEVVIKALGRAISKAVSVAEILKRRFLkgLHQINKITSSS 66
PHA03309 PHA03309
transcriptional regulator ICP4; Provisional
 149-206 4.42e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 165564 [Multi-domain]  Cd Length: 2033  Bit Score: 37.53  E-value: 4.42e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 24586048   149 GGGAQQQPHPRSQPRHQQQPHKPGAGRGGRPNKRTRPGRNKPGQQPEKPAAEENLPAS 206
Cdd:PHA03309 1561 GGKRPRSSSSSSSASHDRSPSSSSRRRDGRPSSRRRPSRRMSARPPSRPPAAVILRAS 1618
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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