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Conserved domains on  [gi|24652022|ref|NP_610467|]
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receptor mediated endocytosis 8, isoform A [Drosophila melanogaster]

Protein Classification

J domain-containing protein( domain architecture ID 18340985)

J domain-containing protein similar to the N-terminal conserved domain (called J domain) of DnaJ-like proteins, which is involved in regulating the ATPase activity of heat shock protein 70 (Hsp70) by ATP hydrolysis

Gene Ontology:  GO:0006457
PubMed:  9585179|23894646|15170475|9644977

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RME-8_N pfam19432
DNAJ protein RME-8 N-terminal; DNAJ protein RME-8 (receptor-mediated endocytosis-8; Gvr2 in ...
 12-835 0e+00

DNAJ protein RME-8 N-terminal; DNAJ protein RME-8 (receptor-mediated endocytosis-8; Gvr2 in Arabidopsis) is involved in membrane trafficking through early endosomes and in the regulation of endosomal membrane tubulation. It regulates the dynamics of SNX1 (sorting nexin 1) on the endosomal membrane. It coordinates the function of the WASH complex and the retromer SNX dimer through its interaction with FAM21 subunit in WASH complex. This is the N-terminal domain of RME-8, which is required for membrane association and interaction with FAM21 tail domain. It contains critical residues mediating phosphatidylinositol 3-phosphate (PI(3)P) binding, required for its association with endosomes.


:

Pssm-ID: 466078  Cd Length: 819  Bit Score: 1374.23  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022     12 CFLVTKHSWKGRYKRILSIGTAGISTYNPDKLDLTNRWSYSDIVAAAPSKTTNIPHDFVITIKKDKKLDTIKLSSEYRND 91
Cdd:pfam19432    1 CYLVTKHSWKGKYKRIFSIGTLGITTYNPSTLEVTNQWLYSDFISIKPSPKSGGPNEFIITTRKKGKSDTMRFSSEYRAE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022     92 ILSSILKYYKEFAD--KPKNAQRFSAYKYHWSGISLPTVLEVTPCSLDQLDPTTNDVLASYMYKDIEGIIaGISDYEGGI 169
Cdd:pfam19432   81 ILTDALRYRAKFADeyKDKLDQRFNAYKHHWSDRRIPVVLRVTPVGLEQLDPATGEVLASYLYKDIEGII-LVSDYPGGF 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    170 VMAYGGFSRLHLFKALNHHEIVQNIAQRSAQFLGIETKILKSQITLEQFERQRFGKFSGDQFQTSSTEFSVHKITPRHPD 249
Cdd:pfam19432  160 VILYGGFRRLHLFAVENRDELIKKIRENAAEYIGIPIKVAKEPITLDQFKLTRLGKYSSDEHLTSLAEFPVQKISPRHPD 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    250 PVKRILCLTEVTLLERDPQTYSVCTLRPLTDVFALVRDKDNLQRFSIEYKNGIVRNYSTNDRDSLLATVLDAVRSSGNQD 329
Cdd:pfam19432  240 PVRRLLCLSETCLLERDPATYNVVTLRPLKDIFALVRDEEDPQRFSIEYKNGDVRSYTSTERDALLASLLDGVRASGNRD 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    330 VHVRIGNTPRGKRYVPLNSSVDEETEANLMRLVINnfQNPS-KRYEILERFNANVPHSGLNYSVTQDSLFAENKDKLILS 408
Cdd:pfam19432  320 VHVKMRRTDRGLRLGPLSVPVDEEVESQLLKFLIS--PPPGgSFADAVERFNANIPYSGLLHSVTQDGLFAENKEKLIVS 397

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    409 ALQALAQKELDspTAQLSNLELEAIFHALTRLLASKVGYAAFTNLPGFREIIGTKVVAALRRKDLAVTYSAIDMINSLMH 488
Cdd:pfam19432  398 ALEALLEEEGD--QDFISPHELEAQFQALRRLFASKAGFSAFTAVPGFREKLGSKVVRALKRNDEAVSHAAVDMLCALMQ 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    489 SVNSDHDLKQEQLNKSSILSSKSFLETLLNMWTTHVSHGSGALVLSAMLDFMTFALCVPYSETTDGKQFDTLLELVADRG 568
Cdd:pfam19432  476 PMHDNYDLRQEQLNKSSLLSSKKFLEHLLDMLVDHVERGTGALVVAAMLDFLTFALCAPYSETTDGKQFDSLLEMVADRG 555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    569 RYLYKLFQHPSLAIVKGAGLVLRAIIEEGELQVAQQMQALALDEAALCRHLLVALYTPSNDPTQTTQRQLSRHLIGLWLT 648
Cdd:pfam19432  556 RSLFKLFQHPSLAIVKGAGLVMRAIIEEGDPEISARMQELALSEGALLRHLHTALFTTSRDLRLLTNRQLSRHLIALWIT 635

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    649 DSEEAMELFKRIFPAGLLTFLESEETVPESdvEEDKLNFRDNLKFAIQHSNKTRK----NVIEKHLQG-IKHWGMNLIEK 723
Cdd:pfam19432  636 GNPDAMDLLKRILPAGLLDYLDSTEEPPED--EEDLLNTRDNLKMATDHSEQKSGlkeqKTVEKHVEGlLQHWRLRIGLE 713

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    724 QDgaaQALKNRPVVLRNRRQKKKTSdvvVNLPFFFYSFAKDHSLPNLIWNHKTREELRMCLENELRQFLNDRDLAGQMIV 803
Cdd:pfam19432  714 FK---KKFQQRPVVLRKRRQRVKSE---ANWPMFYYQFKKDHAKPDLIWNHKTREELREALENELRAFNQDKELAGDKVI 787

                          810       820       830
                   ....*....|....*....|....*....|..
gi 24652022    804 AWNYQEFEVAYQCLADEIKIGDYYIRLILEKD 835
Cdd:pfam19432  788 SWNHTEFEVRYPSLADEIKIGDYYLRLLLEED 819
GYF_2 pfam14237
GYF domain 2; This domain is found in bacteria, archaea and eukaryotes, and is approximately ...
 972-1026 7.30e-15

GYF domain 2; This domain is found in bacteria, archaea and eukaryotes, and is approximately 50 amino acids in length. It contains an evolutionary conserved signature W-X-Y-X6-11-GPF-X4-M-X2-W-X3-GYF, the site of interaction with proline-rich peptides. Family members include RME-8 (Required for receptor-mediated endocytosis 8), a DNAJC13 protein. RME-8 was first identified as a protein that is required for endocytosis in Caenorhabditis elegans. It coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation. Family members found in Arabidopsis include Arabidopsis trithorax-related3 (Atxr3), also known as set domain group 2 (Sdg2). It is the major enzyme responsible for H3K4me3 in Arabidopsis and SDG2-dependent H3K4m3 is critical for regulating gene expression and plant development. Another family member found in Arabidopsis is Tic56. It is an essential subunit of a 1-MDa protein complex at the inner chloroplast envelope membrane. Furthermore, Tic56 is important for rRNA processing and chloroplast ribosome assembly.


:

Pssm-ID: 464112  Cd Length: 50  Bit Score: 70.65  E-value: 7.30e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 24652022    972 WYYNIekDGQkpeRQGPITYSELKELWQKGLITPKTRCWAIGMDGWRSLQQIPQL 1026
Cdd:pfam14237    1 WYYAV--NGQ---QQGPFSLEELRQLAASGEITPDTLVWREGMDDWKPASDVPEL 50
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 1304-1356 1.51e-11

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


:

Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 61.72  E-value: 1.51e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 24652022   1304 YQDLGIDltktPKPDESMIRKSYYKLAQMYHPDKN---PNGREIFEKVNQAYEFLC 1356
Cdd:pfam00226    3 YEILGVS----PDASDEEIKKAYRKLALKYHPDKNpgdPEAEEKFKEINEAYEVLS 54
 
Name Accession Description Interval E-value
RME-8_N pfam19432
DNAJ protein RME-8 N-terminal; DNAJ protein RME-8 (receptor-mediated endocytosis-8; Gvr2 in ...
 12-835 0e+00

DNAJ protein RME-8 N-terminal; DNAJ protein RME-8 (receptor-mediated endocytosis-8; Gvr2 in Arabidopsis) is involved in membrane trafficking through early endosomes and in the regulation of endosomal membrane tubulation. It regulates the dynamics of SNX1 (sorting nexin 1) on the endosomal membrane. It coordinates the function of the WASH complex and the retromer SNX dimer through its interaction with FAM21 subunit in WASH complex. This is the N-terminal domain of RME-8, which is required for membrane association and interaction with FAM21 tail domain. It contains critical residues mediating phosphatidylinositol 3-phosphate (PI(3)P) binding, required for its association with endosomes.


Pssm-ID: 466078  Cd Length: 819  Bit Score: 1374.23  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022     12 CFLVTKHSWKGRYKRILSIGTAGISTYNPDKLDLTNRWSYSDIVAAAPSKTTNIPHDFVITIKKDKKLDTIKLSSEYRND 91
Cdd:pfam19432    1 CYLVTKHSWKGKYKRIFSIGTLGITTYNPSTLEVTNQWLYSDFISIKPSPKSGGPNEFIITTRKKGKSDTMRFSSEYRAE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022     92 ILSSILKYYKEFAD--KPKNAQRFSAYKYHWSGISLPTVLEVTPCSLDQLDPTTNDVLASYMYKDIEGIIaGISDYEGGI 169
Cdd:pfam19432   81 ILTDALRYRAKFADeyKDKLDQRFNAYKHHWSDRRIPVVLRVTPVGLEQLDPATGEVLASYLYKDIEGII-LVSDYPGGF 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    170 VMAYGGFSRLHLFKALNHHEIVQNIAQRSAQFLGIETKILKSQITLEQFERQRFGKFSGDQFQTSSTEFSVHKITPRHPD 249
Cdd:pfam19432  160 VILYGGFRRLHLFAVENRDELIKKIRENAAEYIGIPIKVAKEPITLDQFKLTRLGKYSSDEHLTSLAEFPVQKISPRHPD 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    250 PVKRILCLTEVTLLERDPQTYSVCTLRPLTDVFALVRDKDNLQRFSIEYKNGIVRNYSTNDRDSLLATVLDAVRSSGNQD 329
Cdd:pfam19432  240 PVRRLLCLSETCLLERDPATYNVVTLRPLKDIFALVRDEEDPQRFSIEYKNGDVRSYTSTERDALLASLLDGVRASGNRD 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    330 VHVRIGNTPRGKRYVPLNSSVDEETEANLMRLVINnfQNPS-KRYEILERFNANVPHSGLNYSVTQDSLFAENKDKLILS 408
Cdd:pfam19432  320 VHVKMRRTDRGLRLGPLSVPVDEEVESQLLKFLIS--PPPGgSFADAVERFNANIPYSGLLHSVTQDGLFAENKEKLIVS 397

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    409 ALQALAQKELDspTAQLSNLELEAIFHALTRLLASKVGYAAFTNLPGFREIIGTKVVAALRRKDLAVTYSAIDMINSLMH 488
Cdd:pfam19432  398 ALEALLEEEGD--QDFISPHELEAQFQALRRLFASKAGFSAFTAVPGFREKLGSKVVRALKRNDEAVSHAAVDMLCALMQ 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    489 SVNSDHDLKQEQLNKSSILSSKSFLETLLNMWTTHVSHGSGALVLSAMLDFMTFALCVPYSETTDGKQFDTLLELVADRG 568
Cdd:pfam19432  476 PMHDNYDLRQEQLNKSSLLSSKKFLEHLLDMLVDHVERGTGALVVAAMLDFLTFALCAPYSETTDGKQFDSLLEMVADRG 555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    569 RYLYKLFQHPSLAIVKGAGLVLRAIIEEGELQVAQQMQALALDEAALCRHLLVALYTPSNDPTQTTQRQLSRHLIGLWLT 648
Cdd:pfam19432  556 RSLFKLFQHPSLAIVKGAGLVMRAIIEEGDPEISARMQELALSEGALLRHLHTALFTTSRDLRLLTNRQLSRHLIALWIT 635

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    649 DSEEAMELFKRIFPAGLLTFLESEETVPESdvEEDKLNFRDNLKFAIQHSNKTRK----NVIEKHLQG-IKHWGMNLIEK 723
Cdd:pfam19432  636 GNPDAMDLLKRILPAGLLDYLDSTEEPPED--EEDLLNTRDNLKMATDHSEQKSGlkeqKTVEKHVEGlLQHWRLRIGLE 713

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    724 QDgaaQALKNRPVVLRNRRQKKKTSdvvVNLPFFFYSFAKDHSLPNLIWNHKTREELRMCLENELRQFLNDRDLAGQMIV 803
Cdd:pfam19432  714 FK---KKFQQRPVVLRKRRQRVKSE---ANWPMFYYQFKKDHAKPDLIWNHKTREELREALENELRAFNQDKELAGDKVI 787

                          810       820       830
                   ....*....|....*....|....*....|..
gi 24652022    804 AWNYQEFEVAYQCLADEIKIGDYYIRLILEKD 835
Cdd:pfam19432  788 SWNHTEFEVRYPSLADEIKIGDYYLRLLLEED 819
GYF_2 pfam14237
GYF domain 2; This domain is found in bacteria, archaea and eukaryotes, and is approximately ...
 972-1026 7.30e-15

GYF domain 2; This domain is found in bacteria, archaea and eukaryotes, and is approximately 50 amino acids in length. It contains an evolutionary conserved signature W-X-Y-X6-11-GPF-X4-M-X2-W-X3-GYF, the site of interaction with proline-rich peptides. Family members include RME-8 (Required for receptor-mediated endocytosis 8), a DNAJC13 protein. RME-8 was first identified as a protein that is required for endocytosis in Caenorhabditis elegans. It coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation. Family members found in Arabidopsis include Arabidopsis trithorax-related3 (Atxr3), also known as set domain group 2 (Sdg2). It is the major enzyme responsible for H3K4me3 in Arabidopsis and SDG2-dependent H3K4m3 is critical for regulating gene expression and plant development. Another family member found in Arabidopsis is Tic56. It is an essential subunit of a 1-MDa protein complex at the inner chloroplast envelope membrane. Furthermore, Tic56 is important for rRNA processing and chloroplast ribosome assembly.


Pssm-ID: 464112  Cd Length: 50  Bit Score: 70.65  E-value: 7.30e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 24652022    972 WYYNIekDGQkpeRQGPITYSELKELWQKGLITPKTRCWAIGMDGWRSLQQIPQL 1026
Cdd:pfam14237    1 WYYAV--NGQ---QQGPFSLEELRQLAASGEITPDTLVWREGMDDWKPASDVPEL 50
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 1304-1356 1.51e-11

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 61.72  E-value: 1.51e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 24652022   1304 YQDLGIDltktPKPDESMIRKSYYKLAQMYHPDKN---PNGREIFEKVNQAYEFLC 1356
Cdd:pfam00226    3 YEILGVS----PDASDEEIKKAYRKLALKYHPDKNpgdPEAEEKFKEINEAYEVLS 54
DnaJ smart00271
DnaJ molecular chaperone homology domain;
1303-1356 1.09e-10

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 59.17  E-value: 1.09e-10
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 24652022    1303 AYQDLGIdltkTPKPDESMIRKSYYKLAQMYHPDKNPNGR----EIFEKVNQAYEFLC 1356
Cdd:smart00271    3 YYEILGV----PRDASLDEIKKAYRKLALKYHPDKNPGDKeeaeEKFKEINEAYEVLS 56
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 1304-1356 1.54e-10

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 58.33  E-value: 1.54e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 24652022 1304 YQDLGIDltktPKPDESMIRKSYYKLAQMYHPDKNPN---GREIFEKVNQAYEFLC 1356
Cdd:cd06257    3 YDILGVP----PDASDEEIKKAYRKLALKYHPDKNPDdpeAEEKFKEINEAYEVLS 54
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 1304-1355 3.26e-09

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 57.40  E-value: 3.26e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 24652022 1304 YQDLGIDLTKTPkpDEsmIRKSYYKLAQMYHPDKNPNG---REIFEKVNQAYEFL 1355
Cdd:COG0484    3 YEILGVSRDASA--EE--IKKAYRKLAKKYHPDRNPGDpeaEEKFKEINEAYEVL 53
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 1304-1355 2.75e-07

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 55.58  E-value: 2.75e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 24652022  1304 YQDLGIdlTKTPKPDEsmIRKSYYKLAQMYHPDKNPNGREI---FEKVNQAYEFL 1355
Cdd:PRK14281    6 YEVLGV--SRSADKDE--IKKAYRKLALKYHPDKNPDNKEAeehFKEVNEAYEVL 56
 
Name Accession Description Interval E-value
RME-8_N pfam19432
DNAJ protein RME-8 N-terminal; DNAJ protein RME-8 (receptor-mediated endocytosis-8; Gvr2 in ...
 12-835 0e+00

DNAJ protein RME-8 N-terminal; DNAJ protein RME-8 (receptor-mediated endocytosis-8; Gvr2 in Arabidopsis) is involved in membrane trafficking through early endosomes and in the regulation of endosomal membrane tubulation. It regulates the dynamics of SNX1 (sorting nexin 1) on the endosomal membrane. It coordinates the function of the WASH complex and the retromer SNX dimer through its interaction with FAM21 subunit in WASH complex. This is the N-terminal domain of RME-8, which is required for membrane association and interaction with FAM21 tail domain. It contains critical residues mediating phosphatidylinositol 3-phosphate (PI(3)P) binding, required for its association with endosomes.


Pssm-ID: 466078  Cd Length: 819  Bit Score: 1374.23  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022     12 CFLVTKHSWKGRYKRILSIGTAGISTYNPDKLDLTNRWSYSDIVAAAPSKTTNIPHDFVITIKKDKKLDTIKLSSEYRND 91
Cdd:pfam19432    1 CYLVTKHSWKGKYKRIFSIGTLGITTYNPSTLEVTNQWLYSDFISIKPSPKSGGPNEFIITTRKKGKSDTMRFSSEYRAE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022     92 ILSSILKYYKEFAD--KPKNAQRFSAYKYHWSGISLPTVLEVTPCSLDQLDPTTNDVLASYMYKDIEGIIaGISDYEGGI 169
Cdd:pfam19432   81 ILTDALRYRAKFADeyKDKLDQRFNAYKHHWSDRRIPVVLRVTPVGLEQLDPATGEVLASYLYKDIEGII-LVSDYPGGF 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    170 VMAYGGFSRLHLFKALNHHEIVQNIAQRSAQFLGIETKILKSQITLEQFERQRFGKFSGDQFQTSSTEFSVHKITPRHPD 249
Cdd:pfam19432  160 VILYGGFRRLHLFAVENRDELIKKIRENAAEYIGIPIKVAKEPITLDQFKLTRLGKYSSDEHLTSLAEFPVQKISPRHPD 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    250 PVKRILCLTEVTLLERDPQTYSVCTLRPLTDVFALVRDKDNLQRFSIEYKNGIVRNYSTNDRDSLLATVLDAVRSSGNQD 329
Cdd:pfam19432  240 PVRRLLCLSETCLLERDPATYNVVTLRPLKDIFALVRDEEDPQRFSIEYKNGDVRSYTSTERDALLASLLDGVRASGNRD 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    330 VHVRIGNTPRGKRYVPLNSSVDEETEANLMRLVINnfQNPS-KRYEILERFNANVPHSGLNYSVTQDSLFAENKDKLILS 408
Cdd:pfam19432  320 VHVKMRRTDRGLRLGPLSVPVDEEVESQLLKFLIS--PPPGgSFADAVERFNANIPYSGLLHSVTQDGLFAENKEKLIVS 397

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    409 ALQALAQKELDspTAQLSNLELEAIFHALTRLLASKVGYAAFTNLPGFREIIGTKVVAALRRKDLAVTYSAIDMINSLMH 488
Cdd:pfam19432  398 ALEALLEEEGD--QDFISPHELEAQFQALRRLFASKAGFSAFTAVPGFREKLGSKVVRALKRNDEAVSHAAVDMLCALMQ 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    489 SVNSDHDLKQEQLNKSSILSSKSFLETLLNMWTTHVSHGSGALVLSAMLDFMTFALCVPYSETTDGKQFDTLLELVADRG 568
Cdd:pfam19432  476 PMHDNYDLRQEQLNKSSLLSSKKFLEHLLDMLVDHVERGTGALVVAAMLDFLTFALCAPYSETTDGKQFDSLLEMVADRG 555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    569 RYLYKLFQHPSLAIVKGAGLVLRAIIEEGELQVAQQMQALALDEAALCRHLLVALYTPSNDPTQTTQRQLSRHLIGLWLT 648
Cdd:pfam19432  556 RSLFKLFQHPSLAIVKGAGLVMRAIIEEGDPEISARMQELALSEGALLRHLHTALFTTSRDLRLLTNRQLSRHLIALWIT 635

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    649 DSEEAMELFKRIFPAGLLTFLESEETVPESdvEEDKLNFRDNLKFAIQHSNKTRK----NVIEKHLQG-IKHWGMNLIEK 723
Cdd:pfam19432  636 GNPDAMDLLKRILPAGLLDYLDSTEEPPED--EEDLLNTRDNLKMATDHSEQKSGlkeqKTVEKHVEGlLQHWRLRIGLE 713

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022    724 QDgaaQALKNRPVVLRNRRQKKKTSdvvVNLPFFFYSFAKDHSLPNLIWNHKTREELRMCLENELRQFLNDRDLAGQMIV 803
Cdd:pfam19432  714 FK---KKFQQRPVVLRKRRQRVKSE---ANWPMFYYQFKKDHAKPDLIWNHKTREELREALENELRAFNQDKELAGDKVI 787

                          810       820       830
                   ....*....|....*....|....*....|..
gi 24652022    804 AWNYQEFEVAYQCLADEIKIGDYYIRLILEKD 835
Cdd:pfam19432  788 SWNHTEFEVRYPSLADEIKIGDYYLRLLLEED 819
GYF_2 pfam14237
GYF domain 2; This domain is found in bacteria, archaea and eukaryotes, and is approximately ...
 972-1026 7.30e-15

GYF domain 2; This domain is found in bacteria, archaea and eukaryotes, and is approximately 50 amino acids in length. It contains an evolutionary conserved signature W-X-Y-X6-11-GPF-X4-M-X2-W-X3-GYF, the site of interaction with proline-rich peptides. Family members include RME-8 (Required for receptor-mediated endocytosis 8), a DNAJC13 protein. RME-8 was first identified as a protein that is required for endocytosis in Caenorhabditis elegans. It coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation. Family members found in Arabidopsis include Arabidopsis trithorax-related3 (Atxr3), also known as set domain group 2 (Sdg2). It is the major enzyme responsible for H3K4me3 in Arabidopsis and SDG2-dependent H3K4m3 is critical for regulating gene expression and plant development. Another family member found in Arabidopsis is Tic56. It is an essential subunit of a 1-MDa protein complex at the inner chloroplast envelope membrane. Furthermore, Tic56 is important for rRNA processing and chloroplast ribosome assembly.


Pssm-ID: 464112  Cd Length: 50  Bit Score: 70.65  E-value: 7.30e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 24652022    972 WYYNIekDGQkpeRQGPITYSELKELWQKGLITPKTRCWAIGMDGWRSLQQIPQL 1026
Cdd:pfam14237    1 WYYAV--NGQ---QQGPFSLEELRQLAASGEITPDTLVWREGMDDWKPASDVPEL 50
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 1304-1356 1.51e-11

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 61.72  E-value: 1.51e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 24652022   1304 YQDLGIDltktPKPDESMIRKSYYKLAQMYHPDKN---PNGREIFEKVNQAYEFLC 1356
Cdd:pfam00226    3 YEILGVS----PDASDEEIKKAYRKLALKYHPDKNpgdPEAEEKFKEINEAYEVLS 54
DnaJ smart00271
DnaJ molecular chaperone homology domain;
1303-1356 1.09e-10

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 59.17  E-value: 1.09e-10
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 24652022    1303 AYQDLGIdltkTPKPDESMIRKSYYKLAQMYHPDKNPNGR----EIFEKVNQAYEFLC 1356
Cdd:smart00271    3 YYEILGV----PRDASLDEIKKAYRKLALKYHPDKNPGDKeeaeEKFKEINEAYEVLS 56
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 1304-1356 1.54e-10

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 58.33  E-value: 1.54e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 24652022 1304 YQDLGIDltktPKPDESMIRKSYYKLAQMYHPDKNPN---GREIFEKVNQAYEFLC 1356
Cdd:cd06257    3 YDILGVP----PDASDEEIKKAYRKLALKYHPDKNPDdpeAEEKFKEINEAYEVLS 54
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 1304-1355 3.26e-09

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 57.40  E-value: 3.26e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 24652022 1304 YQDLGIDLTKTPkpDEsmIRKSYYKLAQMYHPDKNPNG---REIFEKVNQAYEFL 1355
Cdd:COG0484    3 YEILGVSRDASA--EE--IKKAYRKLAKKYHPDRNPGDpeaEEKFKEINEAYEVL 53
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
1298-1357 2.25e-07

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 50.87  E-value: 2.25e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24652022 1298 MTIQQAYQDLGIdltkTPKPDESMIRKSYYKLAQMYHPDKNPNGREI----FEKVNQAYEFLCS 1357
Cdd:COG2214    2 PDLKDHYAVLGV----PPDASLEEIRQAYRRLAKLLHPDRGGELKALaeelFQRLNEAYEVLSD 61
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 1304-1355 2.75e-07

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 55.58  E-value: 2.75e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 24652022  1304 YQDLGIdlTKTPKPDEsmIRKSYYKLAQMYHPDKNPNGREI---FEKVNQAYEFL 1355
Cdd:PRK14281    6 YEVLGV--SRSADKDE--IKKAYRKLALKYHPDKNPDNKEAeehFKEVNEAYEVL 56
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 1304-1355 5.07e-06

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 51.38  E-value: 5.07e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 24652022  1304 YQDLGIdlTKTPKPDEsmIRKSYYKLAQMYHPDKNPNGREI---FEKVNQAYEFL 1355
Cdd:PRK14284    4 YTILGV--SKTASPEE--IKKAYRKLAVKYHPDKNPGDAEAekrFKEVSEAYEVL 54
PRK14276 PRK14276
chaperone protein DnaJ; Provisional
 1298-1355 9.05e-06

chaperone protein DnaJ; Provisional


Pssm-ID: 237653 [Multi-domain]  Cd Length: 380  Bit Score: 50.47  E-value: 9.05e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022  1298 MTIQQAYQDLGIDltKTPKPDEsmIRKSYYKLAQMYHPDKN--PNGREIFEKVNQAYEFL 1355
Cdd:PRK14276    1 MNNTEYYDRLGVS--KDASQDE--IKKAYRKLSKKYHPDINkePGAEEKYKEVQEAYETL 56
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 1304-1355 2.96e-05

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 48.99  E-value: 2.96e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 24652022  1304 YQDLGIDltKTPKPDEsmIRKSYYKLAQMYHPDKNP---NGREIFEKVNQAYEFL 1355
Cdd:PRK10767    7 YEVLGVS--RNASEDE--IKKAYRKLAMKYHPDRNPgdkEAEEKFKEIKEAYEVL 57
PRK14285 PRK14285
chaperone protein DnaJ; Provisional
 1304-1359 3.19e-05

chaperone protein DnaJ; Provisional


Pssm-ID: 172773 [Multi-domain]  Cd Length: 365  Bit Score: 48.83  E-value: 3.19e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 24652022  1304 YQDLGidLTKTPKPDEsmIRKSYYKLAQMYHPDKNPNGRE---IFEKVNQAYEFLCSRN 1359
Cdd:PRK14285    6 YEILG--LSKGASKDE--IKKAYRKIAIKYHPDKNKGNKEaesIFKEATEAYEVLIDDN 60
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 1304-1355 3.84e-05

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 48.61  E-value: 3.84e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 24652022  1304 YQDLGIdlTKTPKPDEsmIRKSYYKLAQMYHPD--KNPNGREIFEKVNQAYEFL 1355
Cdd:PRK14291    6 YEILGV--SRNATQEE--IKKAYRRLARKYHPDfnKNPEAEEKFKEINEAYQVL 55
PRK14297 PRK14297
molecular chaperone DnaJ;
1298-1355 5.21e-05

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 48.24  E-value: 5.21e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24652022  1298 MTIQQAYQDLGidLTKTPKPDEsmIRKSYYKLAQMYHPDKNPNGREI---FEKVNQAYEFL 1355
Cdd:PRK14297    1 MASKDYYEVLG--LEKGASDDE--IKKAFRKLAIKYHPDKNKGNKEAeekFKEINEAYQVL 57
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 1304-1358 8.56e-05

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 47.45  E-value: 8.56e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 24652022  1304 YQDLGIdlTKTPKPDEsmIRKSYYKLAQMYHPDKNPNGRE---IFEKVNQAYEFLCSR 1358
Cdd:PRK14294    7 YEILGV--TRDASEEE--IKKSYRKLAMKYHPDRNPGDKEaeeLFKEAAEAYEVLSDP 60
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 1298-1355 1.56e-04

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 46.09  E-value: 1.56e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022  1298 MTIQQAYQDLGIdlTKTPKPDEsmIRKSYYKLAQMYHPD--KNPNGREIFEKVNQAYEFL 1355
Cdd:PRK14299    1 MAYKDYYAILGV--PKNASQDE--IKKAFKKLARKYHPDvnKSPGAEEKFKEINEAYTVL 56
PRK14289 PRK14289
molecular chaperone DnaJ;
1298-1355 1.83e-04

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 46.36  E-value: 1.83e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24652022  1298 MTIQQAYQDLGIdlTKTPKPDEsmIRKSYYKLAQMYHPDKNPNGREI---FEKVNQAYEFL 1355
Cdd:PRK14289    2 AEKRDYYEVLGV--SKTATVDE--IKKAYRKKAIQYHPDKNPGDKEAeekFKEAAEAYDVL 58
PRK14279 PRK14279
molecular chaperone DnaJ;
1304-1355 2.22e-04

molecular chaperone DnaJ;


Pssm-ID: 237655 [Multi-domain]  Cd Length: 392  Bit Score: 46.26  E-value: 2.22e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 24652022  1304 YQDLGIdlTKTPKPDEsmIRKSYYKLAQMYHPDKNPN---GREIFEKVNQAYEFL 1355
Cdd:PRK14279   12 YKELGV--SSDASAEE--IKKAYRKLARELHPDANPGdpaAEERFKAVSEAHDVL 62
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 1304-1355 4.04e-04

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 45.20  E-value: 4.04e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 24652022  1304 YQDLGIDLTKtpkpDESMIRKSYYKLAQMYHPDKN--PNGREIFEKVNQAYEFL 1355
Cdd:PRK14283    8 YEVLGVDRNA----DKKEIKKAYRKLARKYHPDVSeeEGAEEKFKEISEAYAVL 57
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 1299-1355 4.17e-04

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 45.22  E-value: 4.17e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 24652022  1299 TIQQAYQDLGidLTKTPKPDEsmIRKSYYKLAQMYHPDKN--PNGREIFEKVNQAYEFL 1355
Cdd:PRK14298    3 TTRDYYEILG--LSKDASVED--IKKAYRKLAMKYHPDKNkePDAEEKFKEISEAYAVL 57
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 1304-1368 5.74e-04

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 44.66  E-value: 5.74e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022  1304 YQDLGIDLTKTpkpdESMIRKSYYKLAQMYHPDKNPN--GREIFEKVNQAYEFLC---SRNVWSSGGpDP 1368
Cdd:PRK14278    6 YGLLGVSRNAS----DAEIKRAYRKLARELHPDVNPDeeAQEKFKEISVAYEVLSdpeKRRIVDLGG-DP 70
PRK14293 PRK14293
molecular chaperone DnaJ;
1304-1355 6.47e-04

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 44.60  E-value: 6.47e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 24652022  1304 YQDLGIDltKTPKPDEsmIRKSYYKLAQMYHPD--KNPNGREIFEKVNQAYEFL 1355
Cdd:PRK14293    6 YEILGVS--RDADKDE--LKRAYRRLARKYHPDvnKEPGAEDRFKEINRAYEVL 55
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 1304-1355 8.00e-04

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 44.11  E-value: 8.00e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 24652022  1304 YQDLGIdlTKTPKPDEsmIRKSYYKLAQMYHPDKNPN--GREIFEKVNQAYEFL 1355
Cdd:PRK14292    5 YELLGV--SRTASADE--IKSAYRKLALKYHPDRNKEkgAAEKFAQINEAYAVL 54
PRK14295 PRK14295
molecular chaperone DnaJ;
1304-1368 9.90e-04

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 44.07  E-value: 9.90e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24652022  1304 YQDLGIdlTKTPKPDEsmIRKSYYKLAQMYHPDKN---PNGREIFEKVNQAYEFLC----------SRNVWSSGGPDP 1368
Cdd:PRK14295   12 YKVLGV--PKDATEAE--IKKAYRKLAREYHPDANkgdAKAEERFKEISEAYDVLSdekkrkeydeARSLFGNGGFRP 85
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 1298-1369 1.19e-03

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 43.84  E-value: 1.19e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24652022  1298 MTIQQAYQDLGIDltKTPKPDEsmIRKSYYKLAQMYHPD--KNPNGREIFEKVNQAYEFLCSRNVWSS----GGPDPN 1369
Cdd:PRK14287    1 MSKRDYYEVLGVD--RNASVDE--VKKAYRKLARKYHPDvnKAPDAEDKFKEVKEAYDTLSDPQKKAHydqfGHTDPN 74
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
 1298-1355 1.25e-03

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 43.78  E-value: 1.25e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652022  1298 MTIQQAYQDLGIDLTKTpkpdESMIRKSYYKLAQMYHPD--KNPNGREIFEKVNQAYEFL 1355
Cdd:PRK14296    1 MKKKDYYEVLGVSKTAS----EQEIRQAYRKLAKQYHPDlnKSPDAHDKMVEINEAADVL 56
PRK14300 PRK14300
chaperone protein DnaJ; Provisional
 1301-1355 2.62e-03

chaperone protein DnaJ; Provisional


Pssm-ID: 172788 [Multi-domain]  Cd Length: 372  Bit Score: 42.69  E-value: 2.62e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 24652022  1301 QQAYQDLGIDLTKTpkpdESMIRKSYYKLAQMYHPDKNPNG--REIFEKVNQAYEFL 1355
Cdd:PRK14300    3 QDYYQILGVSKTAS----QADLKKAYLKLAKQYHPDTTDAKdaEKKFKEINAAYDVL 55
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 1304-1355 5.87e-03

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 41.46  E-value: 5.87e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 24652022  1304 YQDLGIDLTKTpkpdESMIRKSYYKLAQMYHPDKNPNGR----EIFEKVNQAYEFL 1355
Cdd:PRK14290    6 YKILGVDRNAS----QEDIKKAFRELAKKWHPDLHPGNKaeaeEKFKEISEAYEVL 57
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 1318-1355 5.92e-03

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 41.65  E-value: 5.92e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 24652022  1318 DESMIRKSYYKLAQMYHPDKNPNGREI---FEKVNQAYEFL 1355
Cdd:PRK14301   17 SEDEIKKAYRKLALQYHPDRNPDNPEAeqkFKEAAEAYEVL 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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