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Conserved domains on  [gi|19922328|ref|NP_611045|]
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uncharacterized protein Dmel_CG8187 [Drosophila melanogaster]

Protein Classification

DUF4097 family beta strand repeat-containing protein( domain architecture ID 1903587)

DUF4097 family beta strand repeat-containing protein similar to Homo sapiens protein FAM185A

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YvlB super family cl43909
Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function ...
89-274 9.59e-06

Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function unknown];


The actual alignment was detected with superfamily member COG3595:

Pssm-ID: 442814 [Multi-domain]  Cd Length: 254  Bit Score: 46.39  E-value: 9.59e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922328  89 VSLDVKVTDEDKVVNVVVKQLAEQPSKLECHLQIPVRSDVSVDAKGSVRVEGIQSELLQVKAKEGILTknikATHINLYS 168
Cdd:COG3595  17 VVAGSIVVGLKTSRGSVDASSGGSVRRTVALGVDTGAALGGVDGVGGNGLAGASYLRVTSSGDVRVSG----VDDVSVKT 92
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922328 169 ENGNI---NCQGTLlgkitQIESQNGNIAMDKLQGDSLNCSTKAGSIVTDCCYVEKSKFQTQTGRLELKNVhkSSEVHVH 245
Cdd:COG3595  93 SSGDVtveDLSGDL-----TVKTVSGDIELSGLTGDEVELETVSGDITVKDGVGGDVEAKTVSGDITVDGA--SGSVEAK 165
                       170       180       190
                ....*....|....*....|....*....|...
gi 19922328 246 QSS---DLNMTGVH-GNIQITTKGGNLNVQLSE 274
Cdd:COG3595 166 TVSgdiRLTLEGAVaGRVKLKTVSGDVEVGLPE 198
 
Name Accession Description Interval E-value
YvlB COG3595
Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function ...
89-274 9.59e-06

Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function unknown];


Pssm-ID: 442814 [Multi-domain]  Cd Length: 254  Bit Score: 46.39  E-value: 9.59e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922328  89 VSLDVKVTDEDKVVNVVVKQLAEQPSKLECHLQIPVRSDVSVDAKGSVRVEGIQSELLQVKAKEGILTknikATHINLYS 168
Cdd:COG3595  17 VVAGSIVVGLKTSRGSVDASSGGSVRRTVALGVDTGAALGGVDGVGGNGLAGASYLRVTSSGDVRVSG----VDDVSVKT 92
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922328 169 ENGNI---NCQGTLlgkitQIESQNGNIAMDKLQGDSLNCSTKAGSIVTDCCYVEKSKFQTQTGRLELKNVhkSSEVHVH 245
Cdd:COG3595  93 SSGDVtveDLSGDL-----TVKTVSGDIELSGLTGDEVELETVSGDITVKDGVGGDVEAKTVSGDITVDGA--SGSVEAK 165
                       170       180       190
                ....*....|....*....|....*....|...
gi 19922328 246 QSS---DLNMTGVH-GNIQITTKGGNLNVQLSE 274
Cdd:COG3595 166 TVSgdiRLTLEGAVaGRVKLKTVSGDVEVGLPE 198
DUF4097 pfam13349
Putative adhesin; This has a putative all-beta structure with a twenty-residue repeat with a ...
164-274 8.19e-04

Putative adhesin; This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.


Pssm-ID: 433135 [Multi-domain]  Cd Length: 246  Bit Score: 40.77  E-value: 8.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922328   164 INLYSENGNINCQGTLLGKITQIESQNGNIAMDKLQGDSLNCSTKAGSIVTDCCYVEKSKFQTQTGRLELKNVhKSSEVH 243
Cdd:pfam13349  80 LTVKTSSGDISVSDNLALKDVILSSNSGDITLKNVSAENLTIKSTSGDVSIDGSSAKKSKLITTSGDIDLNNV-SGKDLD 158
                          90       100       110
                  ....*....|....*....|....*....|....
gi 19922328   244 VHQSS---DLNMTGVHGNIQITTKGGNLNVQLSE 274
Cdd:pfam13349 159 LKSTSgdiNVSNTTIAGSLKITATSGDIDLSLPD 192
 
Name Accession Description Interval E-value
YvlB COG3595
Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function ...
89-274 9.59e-06

Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function unknown];


Pssm-ID: 442814 [Multi-domain]  Cd Length: 254  Bit Score: 46.39  E-value: 9.59e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922328  89 VSLDVKVTDEDKVVNVVVKQLAEQPSKLECHLQIPVRSDVSVDAKGSVRVEGIQSELLQVKAKEGILTknikATHINLYS 168
Cdd:COG3595  17 VVAGSIVVGLKTSRGSVDASSGGSVRRTVALGVDTGAALGGVDGVGGNGLAGASYLRVTSSGDVRVSG----VDDVSVKT 92
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922328 169 ENGNI---NCQGTLlgkitQIESQNGNIAMDKLQGDSLNCSTKAGSIVTDCCYVEKSKFQTQTGRLELKNVhkSSEVHVH 245
Cdd:COG3595  93 SSGDVtveDLSGDL-----TVKTVSGDIELSGLTGDEVELETVSGDITVKDGVGGDVEAKTVSGDITVDGA--SGSVEAK 165
                       170       180       190
                ....*....|....*....|....*....|...
gi 19922328 246 QSS---DLNMTGVH-GNIQITTKGGNLNVQLSE 274
Cdd:COG3595 166 TVSgdiRLTLEGAVaGRVKLKTVSGDVEVGLPE 198
DUF4097 pfam13349
Putative adhesin; This has a putative all-beta structure with a twenty-residue repeat with a ...
164-274 8.19e-04

Putative adhesin; This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.


Pssm-ID: 433135 [Multi-domain]  Cd Length: 246  Bit Score: 40.77  E-value: 8.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922328   164 INLYSENGNINCQGTLLGKITQIESQNGNIAMDKLQGDSLNCSTKAGSIVTDCCYVEKSKFQTQTGRLELKNVhKSSEVH 243
Cdd:pfam13349  80 LTVKTSSGDISVSDNLALKDVILSSNSGDITLKNVSAENLTIKSTSGDVSIDGSSAKKSKLITTSGDIDLNNV-SGKDLD 158
                          90       100       110
                  ....*....|....*....|....*....|....
gi 19922328   244 VHQSS---DLNMTGVHGNIQITTKGGNLNVQLSE 274
Cdd:pfam13349 159 LKSTSgdiNVSNTTIAGSLKITATSGDIDLSLPD 192
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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