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Conserved domains on  [gi|19922368|ref|NP_611094|]
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uncharacterized protein Dmel_CG8441, isoform A [Drosophila melanogaster]

Protein Classification

PRKRIP1 family protein( domain architecture ID 12071477)

PRKR-interacting protein 1 (PRKRIP1) family protein similar to human PRKRIP1 that binds double-stranded RNA and inhibits EIF2AK2 kinase activity

Gene Ontology:  GO:0003725

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF1168 pfam06658
Protein of unknown function (DUF1168); This family consists of several hypothetical eukaryotic ...
 58-194 5.93e-38

Protein of unknown function (DUF1168); This family consists of several hypothetical eukaryotic proteins of unknown function.


:

Pssm-ID: 461977  Cd Length: 136  Bit Score: 129.71  E-value: 5.93e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922368    58 PDKPVVIPEQRRERDfMSSVPTFVRNVMGSSAGAGSGEFHVYRHLRRKEYARQKNIQNQSAREAADEAYQQKLDDNRRAA 137
Cdd:pfam06658   1 PDKPIPIPERPKEKN-PRAPPEFVRNVMGSSAGAGSGEFHVYRHLRRREYERLRLIEEQSKKEEEDEEFQQKLEENKRKA 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 19922368   138 EEKTAKKRAKRLKRKQRAKKPREDKKPLAKEASEDSNTDSEEEPTEEKAESSPEEGQ 194
Cdd:pfam06658  80 EEKTAKKRAKRLKKKQKAKKKKKAKKGNKEDKATKEDSSDSDSDSEEDEEKEENEEE 136
 
Name Accession Description Interval E-value
DUF1168 pfam06658
Protein of unknown function (DUF1168); This family consists of several hypothetical eukaryotic ...
 58-194 5.93e-38

Protein of unknown function (DUF1168); This family consists of several hypothetical eukaryotic proteins of unknown function.


Pssm-ID: 461977  Cd Length: 136  Bit Score: 129.71  E-value: 5.93e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922368    58 PDKPVVIPEQRRERDfMSSVPTFVRNVMGSSAGAGSGEFHVYRHLRRKEYARQKNIQNQSAREAADEAYQQKLDDNRRAA 137
Cdd:pfam06658   1 PDKPIPIPERPKEKN-PRAPPEFVRNVMGSSAGAGSGEFHVYRHLRRREYERLRLIEEQSKKEEEDEEFQQKLEENKRKA 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 19922368   138 EEKTAKKRAKRLKRKQRAKKPREDKKPLAKEASEDSNTDSEEEPTEEKAESSPEEGQ 194
Cdd:pfam06658  80 EEKTAKKRAKRLKKKQKAKKKKKAKKGNKEDKATKEDSSDSDSDSEEDEEKEENEEE 136
 
Name Accession Description Interval E-value
DUF1168 pfam06658
Protein of unknown function (DUF1168); This family consists of several hypothetical eukaryotic ...
 58-194 5.93e-38

Protein of unknown function (DUF1168); This family consists of several hypothetical eukaryotic proteins of unknown function.


Pssm-ID: 461977  Cd Length: 136  Bit Score: 129.71  E-value: 5.93e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922368    58 PDKPVVIPEQRRERDfMSSVPTFVRNVMGSSAGAGSGEFHVYRHLRRKEYARQKNIQNQSAREAADEAYQQKLDDNRRAA 137
Cdd:pfam06658   1 PDKPIPIPERPKEKN-PRAPPEFVRNVMGSSAGAGSGEFHVYRHLRRREYERLRLIEEQSKKEEEDEEFQQKLEENKRKA 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 19922368   138 EEKTAKKRAKRLKRKQRAKKPREDKKPLAKEASEDSNTDSEEEPTEEKAESSPEEGQ 194
Cdd:pfam06658  80 EEKTAKKRAKRLKKKQKAKKKKKAKKGNKEDKATKEDSSDSDSDSEEDEEKEENEEE 136
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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