|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
153-560 |
4.09e-26 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 111.95 E-value: 4.09e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 153 SISLLDCSLRNVTFLSDAKIFDNVSLHGLVISSGEIKRVHKSAFLGIRGPLQALGLPGNALMSVPWNALSTLSALERLDL 232
Cdd:COG4886 24 LILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 233 ANNKikalgtaDFVGLTSLVYLELSNNQISSISQrTFVNLRKLEVLKLGGNRLGDYAQSLRSLSQclsLRQLDLQANNLN 312
Cdd:COG4886 104 SGNE-------ELSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPEPLGNLTN---LKSLDLSNNQLT 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 313 GpLSEqTLPGMRNLESLNLNRNLIKSIQnKALANFSRLVSLSLRHNQIDVLqDHAFFGLGALDSLDLSYNGIVAISSasL 392
Cdd:COG4886 173 D-LPE-ELGNLTNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDLPE--L 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 393 QHLSRLTVLDLTHNFLRALTSdlIAPLPSLRELRLAGNDISIVARNAMDGARELESLQMQENPLSCDCSIRPFAEWLQES 472
Cdd:COG4886 247 GNLTNLEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 473 QLHSSLSASCVTPPRLEGAPLLQVPVETLSCDMDNVEKDNANIMQHLETLAKPNQTSPIKDLSEEIILHELHFSTDYGLI 552
Cdd:COG4886 325 LLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLT 404
|
....*...
gi 281363846 553 LTWLLNLS 560
Cdd:COG4886 405 LALLDAVN 412
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
219-433 |
5.73e-14 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 71.74 E-value: 5.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 219 NALSTLSALERLDLANNKIKALgtADFVGLTSLVYLELSNNQISSISQrtFVNLRKLEVLKLGGNRLgdyaQSLRSLSQC 298
Cdd:cd21340 18 DNLSLCKNLKVLYLYDNKITKI--ENLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRI----SVVEGLENL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 299 LSLRQLDLQANNLngPLSEQTLPGMRNLESLnlnrnliksiqnkalanfsrlvSLSLRHnqidvlqdhaffglgaldsLD 378
Cdd:cd21340 90 TNLEELHIENQRL--PPGEKLTFDPRSLAAL----------------------SNSLRV-------------------LN 126
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 281363846 379 LSYNGIVAISSasLQHLSRLTVLDLTHNFLRALT--SDLIAPLPSLRELRLAGNDIS 433
Cdd:cd21340 127 ISGNNIDSLEP--LAPLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGNPVC 181
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
227-285 |
3.39e-12 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 61.77 E-value: 3.39e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 281363846 227 LERLDLANNKIKALGTADFVGLTSLVYLELSNNQISSISQRTFVNLRKLEVLKLGGNRL 285
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
201-408 |
1.39e-11 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 68.34 E-value: 1.39e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 201 GPLQALGLPGNALMSVPWNALSTLSALERLDLANNKIKALGTADFVGLTSLVYLELSNNQIS-SISQRTFvNLRKLEVLK 279
Cdd:PLN00113 380 GNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQgRINSRKW-DMPSLQMLS 458
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 280 LGGNR-LGDYAQSLRSLSqclsLRQLDLQANNLNG--PLSEQTLPgmrNLESLNLNRNLIKSIQNKALANFSRLVSLSLR 356
Cdd:PLN00113 459 LARNKfFGGLPDSFGSKR----LENLDLSRNQFSGavPRKLGSLS---ELMQLKLSENKLSGEIPDELSSCKKLVSLDLS 531
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 281363846 357 HNQIDVLQDHAFFGLGALDSLDLSYNGIVAISSASLQHLSRLTVLDLTHNFL 408
Cdd:PLN00113 532 HNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHL 583
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
454-504 |
7.79e-08 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 49.35 E-value: 7.79e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 281363846 454 NPLSCDCSIRPFAEWLQESQ-LHSSLSASCVTPPRLEGaPLLQVPVETLSCD 504
Cdd:smart00082 1 NPFICDCELRWLLRWLQANEhLQDPVDLRCASPSSLRG-PLLELLHSEFKCP 51
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
427-514 |
1.60e-07 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 55.47 E-value: 1.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 427 LAGNDISIVARNAMDGARELESLQMQENPLSCDCSIRPFAEWLQESQLH--SSLSASCVTPPRLEGAPLLQVPVETLSCD 504
Cdd:TIGR00864 2 ISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKvrQPEAALCAGPGALAGQPLLGIPLLDSGCD 81
|
90
....*....|..
gi 281363846 505 MDNVE--KDNAN 514
Cdd:TIGR00864 82 EEYVAclKDNSS 93
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
153-560 |
4.09e-26 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 111.95 E-value: 4.09e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 153 SISLLDCSLRNVTFLSDAKIFDNVSLHGLVISSGEIKRVHKSAFLGIRGPLQALGLPGNALMSVPWNALSTLSALERLDL 232
Cdd:COG4886 24 LILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 233 ANNKikalgtaDFVGLTSLVYLELSNNQISSISQrTFVNLRKLEVLKLGGNRLGDYAQSLRSLSQclsLRQLDLQANNLN 312
Cdd:COG4886 104 SGNE-------ELSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPEPLGNLTN---LKSLDLSNNQLT 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 313 GpLSEqTLPGMRNLESLNLNRNLIKSIQnKALANFSRLVSLSLRHNQIDVLqDHAFFGLGALDSLDLSYNGIVAISSasL 392
Cdd:COG4886 173 D-LPE-ELGNLTNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDLPE--L 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 393 QHLSRLTVLDLTHNFLRALTSdlIAPLPSLRELRLAGNDISIVARNAMDGARELESLQMQENPLSCDCSIRPFAEWLQES 472
Cdd:COG4886 247 GNLTNLEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 473 QLHSSLSASCVTPPRLEGAPLLQVPVETLSCDMDNVEKDNANIMQHLETLAKPNQTSPIKDLSEEIILHELHFSTDYGLI 552
Cdd:COG4886 325 LLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLT 404
|
....*...
gi 281363846 553 LTWLLNLS 560
Cdd:COG4886 405 LALLDAVN 412
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
219-433 |
5.73e-14 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 71.74 E-value: 5.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 219 NALSTLSALERLDLANNKIKALgtADFVGLTSLVYLELSNNQISSISQrtFVNLRKLEVLKLGGNRLgdyaQSLRSLSQC 298
Cdd:cd21340 18 DNLSLCKNLKVLYLYDNKITKI--ENLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRI----SVVEGLENL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 299 LSLRQLDLQANNLngPLSEQTLPGMRNLESLnlnrnliksiqnkalanfsrlvSLSLRHnqidvlqdhaffglgaldsLD 378
Cdd:cd21340 90 TNLEELHIENQRL--PPGEKLTFDPRSLAAL----------------------SNSLRV-------------------LN 126
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 281363846 379 LSYNGIVAISSasLQHLSRLTVLDLTHNFLRALT--SDLIAPLPSLRELRLAGNDIS 433
Cdd:cd21340 127 ISGNNIDSLEP--LAPLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGNPVC 181
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
203-358 |
2.90e-12 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 66.73 E-value: 2.90e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 203 LQALGLPGNALMSVPwnALSTLSALERLDLANNKIKALGtadfvGLTSLVYLE---LSNNQISSISQrtFVNLRKLEVLK 279
Cdd:cd21340 26 LKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIE-----NLENLVNLKklyLGGNRISVVEG--LENLTNLEELH 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 280 LGGNRLG-------DYAqSLRSLSQClsLRQLDLQANNLNgplSEQTLPGMRNLESLNLNRNLIKSIQN--KALANFSRL 350
Cdd:cd21340 97 IENQRLPpgekltfDPR-SLAALSNS--LRVLNISGNNID---SLEPLAPLRNLEQLDASNNQISDLEEllDLLSSWPSL 170
|
....*...
gi 281363846 351 VSLSLRHN 358
Cdd:cd21340 171 RELDLTGN 178
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
227-285 |
3.39e-12 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 61.77 E-value: 3.39e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 281363846 227 LERLDLANNKIKALGTADFVGLTSLVYLELSNNQISSISQRTFVNLRKLEVLKLGGNRL 285
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
348-406 |
3.60e-12 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 61.77 E-value: 3.60e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 281363846 348 SRLVSLSLRHNQIDVLQDHAFFGLGALDSLDLSYNGIVAISSASLQHLSRLTVLDLTHN 406
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
218-440 |
9.56e-12 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 67.89 E-value: 9.56e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 218 WNALSTLSALERLDLANNKIKALGTADFV----GLTSLVYLELSNNQISSisqRTFVNL-------RKLEVLKLGGNRLG 286
Cdd:COG5238 201 AEALTQNTTVTTLWLKRNPIGDEGAEILAealkGNKSLTTLDLSNNQIGD---EGVIALaealknnTTVETLYLSGNQIG 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 287 dyAQSLRSLSqclslrqldlqannlngplseQTLPGMRNLESLNLNRNLIKSIQNKALANfsrlvslSLRHNQIdvlqdh 366
Cdd:COG5238 278 --AEGAIALA---------------------KALQGNTTLTSLDLSVNRIGDEGAIALAE-------GLQGNKT------ 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 367 affglgaLDSLDLSYNGI-----VAISSAsLQHLSRLTVLDLTHNFLRALTSDLIAPL----PSLRELRLAGNDISIVAR 437
Cdd:COG5238 322 -------LHTLNLAYNGIgaqgaIALAKA-LQENTTLHSLDLSDNQIGDEGAIALAKYlegnTTLRELNLGKNNIGKQGA 393
|
...
gi 281363846 438 NAM 440
Cdd:COG5238 394 EAL 396
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
201-408 |
1.39e-11 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 68.34 E-value: 1.39e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 201 GPLQALGLPGNALMSVPWNALSTLSALERLDLANNKIKALGTADFVGLTSLVYLELSNNQIS-SISQRTFvNLRKLEVLK 279
Cdd:PLN00113 380 GNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQgRINSRKW-DMPSLQMLS 458
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 280 LGGNR-LGDYAQSLRSLSqclsLRQLDLQANNLNG--PLSEQTLPgmrNLESLNLNRNLIKSIQNKALANFSRLVSLSLR 356
Cdd:PLN00113 459 LARNKfFGGLPDSFGSKR----LENLDLSRNQFSGavPRKLGSLS---ELMQLKLSENKLSGEIPDELSSCKKLVSLDLS 531
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 281363846 357 HNQIDVLQDHAFFGLGALDSLDLSYNGIVAISSASLQHLSRLTVLDLTHNFL 408
Cdd:PLN00113 532 HNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHL 583
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
248-457 |
1.45e-11 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 66.22 E-value: 1.45e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 248 LTSLVYLELSNNQISSISQRTFVNLRK---LEVLKLGGNRLGD-----YAQSLRSLSqcLSLRQLDLQANNLNGPLSEQ- 318
Cdd:cd00116 80 GCGLQELDLSDNALGPDGCGVLESLLRsssLQELKLNNNGLGDrglrlLAKGLKDLP--PALEKLVLGRNRLEGASCEAl 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 319 --TLPGMRNLESLNLNRNlikSIQNKALanfsRLVSLSLRHNQidvlqdhaffglgALDSLDLSYNGI----VAISSASL 392
Cdd:cd00116 158 akALRANRDLKELNLANN---GIGDAGI----RALAEGLKANC-------------NLEVLDLNNNGLtdegASALAETL 217
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 281363846 393 QHLSRLTVLDLTHNFLR-----ALTSDLIAPLPSLRELRLAGNDISIVA----RNAMDGARELESLQMQENPLS 457
Cdd:cd00116 218 ASLKSLEVLNLGDNNLTdagaaALASALLSPNISLLTLSLSCNDITDDGakdlAEVLAEKESLLELDLRGNKFG 291
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
324-384 |
1.64e-11 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 59.85 E-value: 1.64e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 281363846 324 RNLESLNLNRNLIKSIQNKALANFSRLVSLSLRHNQIDVLQDHAFFGLGALDSLDLSYNGI 384
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
220-433 |
5.11e-11 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 66.41 E-value: 5.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 220 ALSTLSALERLDLANNKIKALGTADFVGLTSLVYLELSNNQISSISQRTFVNLRKLEVLKLGGNRLGDyaQSLRSLSQCL 299
Cdd:PLN00113 327 ALTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEG--EIPKSLGACR 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 300 SLRQLDLQANNLNGPL---------------SEQTLPG--------MRNLESLNLNRN-----LIKSIQNKALANfsrlv 351
Cdd:PLN00113 405 SLRRVRLQDNSFSGELpseftklplvyfldiSNNNLQGrinsrkwdMPSLQMLSLARNkffggLPDSFGSKRLEN----- 479
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 352 sLSLRHNQIDVLQDHAFFGLGALDSLDLSYNGIVAISSASLQHLSRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGND 431
Cdd:PLN00113 480 -LDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQ 558
|
..
gi 281363846 432 IS 433
Cdd:PLN00113 559 LS 560
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
223-433 |
6.37e-11 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 66.02 E-value: 6.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 223 TLSALERLDLANNKIKALGTADFVGLTSLVYLELSNNQISSISQRTFVNLRKLEVLKLGGNRLgdYAQSLRSLSQCLSLR 302
Cdd:PLN00113 138 SIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQL--VGQIPRELGQMKSLK 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 303 QLDLQANNLNGPLSEQtLPGMRNLESLNL-NRNLIKSIQNkALANFSRLVSLSLRHNQIDVLQDHAFFGLGALDSLDLSY 381
Cdd:PLN00113 216 WIYLGYNNLSGEIPYE-IGGLTSLNHLDLvYNNLTGPIPS-SLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSD 293
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 281363846 382 NGIVAISSASLQHLSRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGNDIS 433
Cdd:PLN00113 294 NSLSGEIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFS 345
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
374-432 |
4.87e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 55.99 E-value: 4.87e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 281363846 374 LDSLDLSYNGIVAISSASLQHLSRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGNDI 432
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
217-419 |
2.33e-09 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 59.68 E-value: 2.33e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 217 PWNALSTLSALERLDLANNKIKALGTAdFV--GLTS----LVYLELSNNQISSISQR----TFVNLRKLEVLKLGGNRLG 286
Cdd:cd00116 100 VLESLLRSSSLQELKLNNNGLGDRGLR-LLakGLKDlppaLEKLVLGRNRLEGASCEalakALRANRDLKELNLANNGIG 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 287 DyaQSLRSLSQCL----SLRQLDLQANNLN----GPLSEqTLPGMRNLESLNLNRNLIKSIQNKALANFSRLVSLSLRhn 358
Cdd:cd00116 179 D--AGIRALAEGLkancNLEVLDLNNNGLTdegaSALAE-TLASLKSLEVLNLGDNNLTDAGAAALASALLSPNISLL-- 253
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 281363846 359 qidvlqdhaffglgaldSLDLSYNGIVAISSASL----QHLSRLTVLDLTHNFLRALTSDLIAPL 419
Cdd:cd00116 254 -----------------TLSLSCNDITDDGAKDLaevlAEKESLLELDLRGNKFGEEGAQLLAES 301
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
203-261 |
3.83e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 53.30 E-value: 3.83e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 281363846 203 LQALGLPGNALMSVPWNALSTLSALERLDLANNKIKALGTADFVGLTSLVYLELSNNQI 261
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
220-457 |
1.06e-08 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 59.09 E-value: 1.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 220 ALSTLSALERLDLANNKIKALGTADFVGLTSLVYLELSNNQISSISQRTFVNLRKLEVLKLGGNRL-GDYAQSLRSLSQc 298
Cdd:PLN00113 255 SLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFtGKIPVALTSLPR- 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 299 lsLRQLDLQANNLNGPLSeQTLPGMRNLESLNLNRNLIKSIQNKALANFSRLVSLSLRHNQID----------------V 362
Cdd:PLN00113 334 --LQVLQLWSNKFSGEIP-KNLGKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEgeipkslgacrslrrvR 410
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 363 LQDHAFFG--------LGALDSLDLSYNGIVA-ISSA-----SLQHLS-----------------RLTVLDLTHNFLRAL 411
Cdd:PLN00113 411 LQDNSFSGelpseftkLPLVYFLDISNNNLQGrINSRkwdmpSLQMLSlarnkffgglpdsfgskRLENLDLSRNQFSGA 490
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 281363846 412 TSDLIAPLPSLRELRLAGNDISIVARNAMDGARELESLQMQENPLS 457
Cdd:PLN00113 491 VPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLS 536
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
197-433 |
1.21e-08 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 58.71 E-value: 1.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 197 LGIRGPLQALGLPGNALMSVPWNALSTLSALERLDLANNKIKA----------------LGTADFVG--------LTSLV 252
Cdd:PLN00113 160 IGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGqiprelgqmkslkwiyLGYNNLSGeipyeiggLTSLN 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 253 YLELSNNQISSISQRTFVNLRKLEVLKLGGNRL-GDYAQSLRSLSQCLSlrqLDLQANNLNGPLSEQTLPgMRNLESLNL 331
Cdd:PLN00113 240 HLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLsGPIPPSIFSLQKLIS---LDLSDNSLSGEIPELVIQ-LQNLEILHL 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 332 NRNLIKSIQNKALANFSRLVSLSLRHNQI--DVLQDhaffgLGA---LDSLDLSYNGIVAISSASLQHLSRLTVLDLTHN 406
Cdd:PLN00113 316 FSNNFTGKIPVALTSLPRLQVLQLWSNKFsgEIPKN-----LGKhnnLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSN 390
|
250 260
....*....|....*....|....*..
gi 281363846 407 FLRALTSDLIAPLPSLRELRLAGNDIS 433
Cdd:PLN00113 391 SLEGEIPKSLGACRSLRRVRLQDNSFS 417
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
249-311 |
1.93e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.37 E-value: 1.93e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 281363846 249 TSLVYLELSNNQISSISQRTFVNLRKLEVLKLGGNRLGDYaqSLRSLSQCLSLRQLDLQANNL 311
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTL--SPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
300-360 |
2.11e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.37 E-value: 2.11e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 281363846 300 SLRQLDLQANNLNGpLSEQTLPGMRNLESLNLNRNLIKSIQNKALANFSRLVSLSLRHNQI 360
Cdd:pfam13855 2 NLRSLDLSNNRLTS-LDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
454-504 |
7.79e-08 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 49.35 E-value: 7.79e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 281363846 454 NPLSCDCSIRPFAEWLQESQ-LHSSLSASCVTPPRLEGaPLLQVPVETLSCD 504
Cdd:smart00082 1 NPFICDCELRWLLRWLQANEhLQDPVDLRCASPSSLRG-PLLELLHSEFKCP 51
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
427-514 |
1.60e-07 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 55.47 E-value: 1.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 427 LAGNDISIVARNAMDGARELESLQMQENPLSCDCSIRPFAEWLQESQLH--SSLSASCVTPPRLEGAPLLQVPVETLSCD 504
Cdd:TIGR00864 2 ISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKvrQPEAALCAGPGALAGQPLLGIPLLDSGCD 81
|
90
....*....|..
gi 281363846 505 MDNVE--KDNAN 514
Cdd:TIGR00864 82 EEYVAclKDNSS 93
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
251-457 |
3.22e-07 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 54.08 E-value: 3.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 251 LVYLELSNNQIS-SISQRTFvNLRKLEVLKLGGNRL-GDYAQSLRSLSQclSLRQLDLQANNLNGPLSEQTLPgmrNLES 328
Cdd:PLN00113 71 VVSIDLSGKNISgKISSAIF-RLPYIQTINLSNNQLsGPIPDDIFTTSS--SLRYLNLSNNNFTGSIPRGSIP---NLET 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 329 LNLNRNLIKSIQNKALANFSRLVSLSLRHNqidVLQDHAFFGLGALDSLD---LSYNGIVAISSASLQHLSRLTVLDLTH 405
Cdd:PLN00113 145 LDLSNNMLSGEIPNDIGSFSSLKVLDLGGN---VLVGKIPNSLTNLTSLEfltLASNQLVGQIPRELGQMKSLKWIYLGY 221
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 281363846 406 NFLRALTSDLIAPLPSLRELRLAGNDISIVARNAMDGARELESLQMQENPLS 457
Cdd:PLN00113 222 NNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLS 273
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
374-433 |
1.94e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 48.27 E-value: 1.94e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 374 LDSLDLSYNGIVAISSASLQHLSRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGNDIS 433
Cdd:PLN03150 444 LQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLS 503
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
396-456 |
7.30e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 41.36 E-value: 7.30e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 281363846 396 SRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGNDISIVARNAMDGARELESLQMQENPL 456
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
129-312 |
4.77e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 43.11 E-value: 4.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 129 HTLRCNIDLHGMMLLADRLRTSPYSISLLDCSLRNvtfLSDAKIFDnvsLHGLVISSGEIKRVHKSaflgiRGPLQALGL 208
Cdd:cd00116 114 KLNNNGLGDRGLRLLAKGLKDLPPALEKLVLGRNR---LEGASCEA---LAKALRANRDLKELNLA-----NNGIGDAGI 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 209 PGNALmsvpwnALSTLSALERLDLANNKIKALGTADFVG----LTSLVYLELSNNQISSISQRTFVN-----LRKLEVLK 279
Cdd:cd00116 183 RALAE------GLKANCNLEVLDLNNNGLTDEGASALAEtlasLKSLEVLNLGDNNLTDAGAAALASallspNISLLTLS 256
|
170 180 190
....*....|....*....|....*....|....*
gi 281363846 280 LGGNRLGDYA--QSLRSLSQCLSLRQLDLQANNLN 312
Cdd:cd00116 257 LSCNDITDDGakDLAEVLAEKESLLELDLRGNKFG 291
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
205-285 |
1.49e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 42.11 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 205 ALGLPGNALMSVPWNALSTLSALERLDLANNKIKALGTADFVGLTSLVYLELSNNQISSISQRTFVNLRKLEVLKLGGNR 284
Cdd:PLN03150 422 GLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNS 501
|
.
gi 281363846 285 L 285
Cdd:PLN03150 502 L 502
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
134-292 |
4.94e-03 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 40.16 E-value: 4.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 134 NIDLHGMMLLADRLRtSPYSISLLDCSLRNVT-----FLSDAkIFDNVSLHGLVISSGEIKRVHKSAF---LGIRGPLQA 205
Cdd:COG5238 247 QIGDEGVIALAEALK-NNTTVETLYLSGNQIGaegaiALAKA-LQGNTTLTSLDLSVNRIGDEGAIALaegLQGNKTLHT 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363846 206 LGLPGNALMSVPWN----ALSTLSALERLDLANNKI-----KALGTAdFVGLTSLVYLELSNNQISSISQRTFV---NLR 273
Cdd:COG5238 325 LNLAYNGIGAQGAIalakALQENTTLHSLDLSDNQIgdegaIALAKY-LEGNTTLRELNLGKNNIGKQGAEALIdalQTN 403
|
170
....*....|....*....
gi 281363846 274 KLEVLKLGGNRLGDYAQSL 292
Cdd:COG5238 404 RLHTLILDGNLIGAEAQQR 422
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
227-265 |
6.42e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 35.30 E-value: 6.42e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 281363846 227 LERLDLANNKIKALGtaDFVGLTSLVYLELS-NNQISSIS 265
Cdd:pfam12799 3 LEVLDLSNNQITDIP--PLAKLPNLETLDLSgNNKITDLS 40
|
|
| |
