NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|20130279|ref|NP_611768|]
View 

uncharacterized protein Dmel_CG13539, isoform A [Drosophila melanogaster]

Protein Classification

aldehyde dehydrogenase family protein; aldehyde dehydrogenase( domain architecture ID 10538358)

aldehyde dehydrogenase family protein is an NAD(P)(+)-dependent enzyme that may oxidize a wide range of endogenous and exogenous aliphatic and aromatic aldehydes to their corresponding carboxylic acids and may play an important role in detoxification| aldehyde dehydrogenase catalyzes the oxidation of a wide range of endogenous and exogenous aliphatic and aromatic aldehydes to their corresponding carboxylic acids and play an important role in detoxification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DUF1487 pfam07368
Protein of unknown function (DUF1487); This family consists of several uncharacterized ...
 37-260 4.15e-113

Protein of unknown function (DUF1487); This family consists of several uncharacterized proteins from Drosophila melanogaster. The function of this family is unknown.


:

Pssm-ID: 254173  Cd Length: 215  Bit Score: 323.94  E-value: 4.15e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20130279    37 SWILPRMMVLFASGDMDQVIEAIVSDMIHPIGTGLVASVLVEESIRDEMIKRIRANLKPMSERIQHHPNYLKTVKLIDRM 116
Cdd:pfam07368   1 AWNSPRLMVIFEDGDVNSALHALVESLHNPFAPGAVATVLVQESIRDEFVERVRSRLKPLSERVANHPSYLKTLEKIDEL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20130279   117 NCSTIHIeefeesdtkKRYGRRMKGSPLIVLDFPQFYFGGKPTAIMTMSTFRNMNEVVKLHSREGLNFDCITVWSAKLAQ 196
Cdd:pfam07368  81 NAKTIHG---------KSEGRPADASPILVCDFPHSFLGGGPTGVVTLHTFRNMKEAVQLHAKEPLPFDSVSIWNEKLAG 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 20130279   197 CFDLLTRVPtVDQWTFNCTKESIK-VPKLPAQPTTTVIIVKNIHYEVHVIGGKIKTIAFPIVDTS 260
Cdd:pfam07368 152 VYDLAARLN-SDQFFINCFNVDLKpIKKPFAAPKNSVVIARGYHYETLVIGGKRKIIVFPVGTIS 215
 
Name Accession Description Interval E-value
DUF1487 pfam07368
Protein of unknown function (DUF1487); This family consists of several uncharacterized ...
 37-260 4.15e-113

Protein of unknown function (DUF1487); This family consists of several uncharacterized proteins from Drosophila melanogaster. The function of this family is unknown.


Pssm-ID: 254173  Cd Length: 215  Bit Score: 323.94  E-value: 4.15e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20130279    37 SWILPRMMVLFASGDMDQVIEAIVSDMIHPIGTGLVASVLVEESIRDEMIKRIRANLKPMSERIQHHPNYLKTVKLIDRM 116
Cdd:pfam07368   1 AWNSPRLMVIFEDGDVNSALHALVESLHNPFAPGAVATVLVQESIRDEFVERVRSRLKPLSERVANHPSYLKTLEKIDEL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20130279   117 NCSTIHIeefeesdtkKRYGRRMKGSPLIVLDFPQFYFGGKPTAIMTMSTFRNMNEVVKLHSREGLNFDCITVWSAKLAQ 196
Cdd:pfam07368  81 NAKTIHG---------KSEGRPADASPILVCDFPHSFLGGGPTGVVTLHTFRNMKEAVQLHAKEPLPFDSVSIWNEKLAG 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 20130279   197 CFDLLTRVPtVDQWTFNCTKESIK-VPKLPAQPTTTVIIVKNIHYEVHVIGGKIKTIAFPIVDTS 260
Cdd:pfam07368 152 VYDLAARLN-SDQFFINCFNVDLKpIKKPFAAPKNSVVIARGYHYETLVIGGKRKIIVFPVGTIS 215
 
Name Accession Description Interval E-value
DUF1487 pfam07368
Protein of unknown function (DUF1487); This family consists of several uncharacterized ...
 37-260 4.15e-113

Protein of unknown function (DUF1487); This family consists of several uncharacterized proteins from Drosophila melanogaster. The function of this family is unknown.


Pssm-ID: 254173  Cd Length: 215  Bit Score: 323.94  E-value: 4.15e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20130279    37 SWILPRMMVLFASGDMDQVIEAIVSDMIHPIGTGLVASVLVEESIRDEMIKRIRANLKPMSERIQHHPNYLKTVKLIDRM 116
Cdd:pfam07368   1 AWNSPRLMVIFEDGDVNSALHALVESLHNPFAPGAVATVLVQESIRDEFVERVRSRLKPLSERVANHPSYLKTLEKIDEL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20130279   117 NCSTIHIeefeesdtkKRYGRRMKGSPLIVLDFPQFYFGGKPTAIMTMSTFRNMNEVVKLHSREGLNFDCITVWSAKLAQ 196
Cdd:pfam07368  81 NAKTIHG---------KSEGRPADASPILVCDFPHSFLGGGPTGVVTLHTFRNMKEAVQLHAKEPLPFDSVSIWNEKLAG 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 20130279   197 CFDLLTRVPtVDQWTFNCTKESIK-VPKLPAQPTTTVIIVKNIHYEVHVIGGKIKTIAFPIVDTS 260
Cdd:pfam07368 152 VYDLAARLN-SDQFFINCFNVDLKpIKKPFAAPKNSVVIARGYHYETLVIGGKRKIIVFPVGTIS 215
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH