NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|23397663|ref|NP_612213|]
View 

phospholipase ABHD3 isoform 1 [Homo sapiens]

Protein Classification

YheT family hydrolase( domain architecture ID 10785476)

YheT family hydrolase

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
YheT COG0429
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
75-402 4.41e-85

Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];


:

Pssm-ID: 440198 [Multi-domain]  Cd Length: 323  Bit Score: 262.39  E-value: 4.41e-85
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663  75 VVTETYYPTVWCWEGRGQTLLRPFITSKPPVQYRNELIKTADGGQISLDWFDNDnstcymdASTRPTILLLPGLTGTSKE 154
Cdd:COG0429   4 LSTSPFRPPWWLRNGHLQTIYPSLFRRRPALPYRRERLELPDGDFVDLDWSDPP-------APSKPLVVLLHGLEGSSDS 76
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663 155 SYILHMIHLSEELGYRCVVFNNRGVAGENLLTPRTYCCANTEDLETVIHHVHSLYPSAPFLAAGVSMGGMLLLNYLGKIG 234
Cdd:COG0429  77 HYARGLARALYARGWDVVRLNFRGCGGEPNLLPRLYHSGDTEDLVWVLAHLRARYPYAPLYAVGFSLGGNLLLKYLGEQG 156
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663 235 SKTP-LMAAATFSVGWNTFACSESLEKPLNWLLFNYYLTTCLQSSVNKHRHmFVKQVDMDHVMKAKSIREFDKRFTSVMF 313
Cdd:COG0429 157 DDAPpLKAAVAVSPPLDLAASADRLERGFNRLYQRYFLRSLKRKLRRKLAL-FPGLIDLEALKRIRTLREFDDAYTAPLH 235
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663 314 GYQTIDDYYTDASPSPRLKSVGIPVLCLNSVDDVFSPSHAIPIEtAKQNPNVALVLTSYGGHIGFLEGIWPRQSTYMDRV 393
Cdd:COG0429 236 GFKDAEDYYQRASALPFLPQIRVPTLILNAADDPFLPPECLPEA-AELNPNVTLELTKHGGHVGFISGKSPGRRYWLERR 314

                ....*....
gi 23397663 394 FKQFVQAMV 402
Cdd:COG0429 315 ILEFLDAHL 323
 
Name Accession Description Interval E-value
YheT COG0429
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
75-402 4.41e-85

Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];


Pssm-ID: 440198 [Multi-domain]  Cd Length: 323  Bit Score: 262.39  E-value: 4.41e-85
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663  75 VVTETYYPTVWCWEGRGQTLLRPFITSKPPVQYRNELIKTADGGQISLDWFDNDnstcymdASTRPTILLLPGLTGTSKE 154
Cdd:COG0429   4 LSTSPFRPPWWLRNGHLQTIYPSLFRRRPALPYRRERLELPDGDFVDLDWSDPP-------APSKPLVVLLHGLEGSSDS 76
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663 155 SYILHMIHLSEELGYRCVVFNNRGVAGENLLTPRTYCCANTEDLETVIHHVHSLYPSAPFLAAGVSMGGMLLLNYLGKIG 234
Cdd:COG0429  77 HYARGLARALYARGWDVVRLNFRGCGGEPNLLPRLYHSGDTEDLVWVLAHLRARYPYAPLYAVGFSLGGNLLLKYLGEQG 156
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663 235 SKTP-LMAAATFSVGWNTFACSESLEKPLNWLLFNYYLTTCLQSSVNKHRHmFVKQVDMDHVMKAKSIREFDKRFTSVMF 313
Cdd:COG0429 157 DDAPpLKAAVAVSPPLDLAASADRLERGFNRLYQRYFLRSLKRKLRRKLAL-FPGLIDLEALKRIRTLREFDDAYTAPLH 235
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663 314 GYQTIDDYYTDASPSPRLKSVGIPVLCLNSVDDVFSPSHAIPIEtAKQNPNVALVLTSYGGHIGFLEGIWPRQSTYMDRV 393
Cdd:COG0429 236 GFKDAEDYYQRASALPFLPQIRVPTLILNAADDPFLPPECLPEA-AELNPNVTLELTKHGGHVGFISGKSPGRRYWLERR 314

                ....*....
gi 23397663 394 FKQFVQAMV 402
Cdd:COG0429 315 ILEFLDAHL 323
PLN02511 PLN02511
hydrolase
39-403 1.02e-82

hydrolase


Pssm-ID: 215282 [Multi-domain]  Cd Length: 388  Bit Score: 258.56  E-value: 1.02e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663   39 GFSVAyAFYYLSSIAKKPQL-VTGGESfsRFLQDHCPVVTETYYPTVWCWEGRGQTLLRPFITSKPPVQYRNELIKTADG 117
Cdd:PLN02511   5 HFSVA-AILAPGQTREHSSLeVIGGGR--DSFLPKFKSLERPYDAFPLLGNRHVETIFASFFRSLPAVRYRRECLRTPDG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663  118 GQISLDWFDNDNSTCYMDAstrPTILLLPGLTGTSKESYILHMIHLSEELGYRCVVFNNRGVAGENLLTPRTYCCANTED 197
Cdd:PLN02511  82 GAVALDWVSGDDRALPADA---PVLILLPGLTGGSDDSYVRHMLLRARSKGWRVVVFNSRGCADSPVTTPQFYSASFTGD 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663  198 LETVIHHVHSLYPSAPFLAAGVSMGGMLLLNYLGKIGSKTPLMAAATFSVGWNTFACSESLEKPLNwLLFNYYLTTCLQS 277
Cdd:PLN02511 159 LRQVVDHVAGRYPSANLYAAGWSLGANILVNYLGEEGENCPLSGAVSLCNPFDLVIADEDFHKGFN-NVYDKALAKALRK 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663  278 SVNKHRHMFV---KQVDMDHVMKAKSIREFDKRFTSVMFGYQTIDDYYTDASPSPRLKSVGIPVLCLNSVDDVFSPSHAI 354
Cdd:PLN02511 238 IFAKHALLFEglgGEYNIPLVANAKTVRDFDDGLTRVSFGFKSVDAYYSNSSSSDSIKHVRVPLLCIQAANDPIAPARGI 317
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 23397663  355 PIETAKQNPNVALVLTSYGGHIGFLEGI-WPRQSTYMDRVFKQFVQAMVE 403
Cdd:PLN02511 318 PREDIKANPNCLLIVTPSGGHLGWVAGPeAPFGAPWTDPVVMEFLEALEE 367
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
140-381 9.05e-11

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 61.75  E-value: 9.05e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663   140 PTILLLPGLTGTSKESYILhMIHLSEeLGYRCVVFNNRGVA-GENLLTPRTYCcanTEDLETVIHHVHSLYPSAPFLAAG 218
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKL-APALAR-DGFRVIALDLRGFGkSSRPKAQDDYR---TDDLAEDLEYILEALGLEKVNLVG 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663   219 VSMGGMLLLNYLGKIGSKtplMAAATFSVGWNTFACSESLEKPLNWLLFNYYLTT---CLQSSVNKHRHMFVKQVDMDHV 295
Cdd:pfam00561  76 HSMGGLIALAYAAKYPDR---VKALVLLGALDPPHELDEADRFILALFPGFFDGFvadFAPNPLGRLVAKLLALLLLRLR 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663   296 MKaKSIREFDKRFTSV-----MFGYQTIDDY---YTDASPSPRLKSVGIPVLCLNSVDDVFSPSHAIPiETAKQNPNVAL 367
Cdd:pfam00561 153 LL-KALPLLNKRFPSGdyalaKSLVTGALLFietWSTELRAKFLGRLDEPTLIIWGDQDPLVPPQALE-KLAQLFPNARL 230
                         250
                  ....*....|....
gi 23397663   368 VLTSYGGHIGFLEG 381
Cdd:pfam00561 231 VVIPDAGHFAFLEG 244
 
Name Accession Description Interval E-value
YheT COG0429
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
75-402 4.41e-85

Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];


Pssm-ID: 440198 [Multi-domain]  Cd Length: 323  Bit Score: 262.39  E-value: 4.41e-85
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663  75 VVTETYYPTVWCWEGRGQTLLRPFITSKPPVQYRNELIKTADGGQISLDWFDNDnstcymdASTRPTILLLPGLTGTSKE 154
Cdd:COG0429   4 LSTSPFRPPWWLRNGHLQTIYPSLFRRRPALPYRRERLELPDGDFVDLDWSDPP-------APSKPLVVLLHGLEGSSDS 76
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663 155 SYILHMIHLSEELGYRCVVFNNRGVAGENLLTPRTYCCANTEDLETVIHHVHSLYPSAPFLAAGVSMGGMLLLNYLGKIG 234
Cdd:COG0429  77 HYARGLARALYARGWDVVRLNFRGCGGEPNLLPRLYHSGDTEDLVWVLAHLRARYPYAPLYAVGFSLGGNLLLKYLGEQG 156
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663 235 SKTP-LMAAATFSVGWNTFACSESLEKPLNWLLFNYYLTTCLQSSVNKHRHmFVKQVDMDHVMKAKSIREFDKRFTSVMF 313
Cdd:COG0429 157 DDAPpLKAAVAVSPPLDLAASADRLERGFNRLYQRYFLRSLKRKLRRKLAL-FPGLIDLEALKRIRTLREFDDAYTAPLH 235
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663 314 GYQTIDDYYTDASPSPRLKSVGIPVLCLNSVDDVFSPSHAIPIEtAKQNPNVALVLTSYGGHIGFLEGIWPRQSTYMDRV 393
Cdd:COG0429 236 GFKDAEDYYQRASALPFLPQIRVPTLILNAADDPFLPPECLPEA-AELNPNVTLELTKHGGHVGFISGKSPGRRYWLERR 314

                ....*....
gi 23397663 394 FKQFVQAMV 402
Cdd:COG0429 315 ILEFLDAHL 323
PLN02511 PLN02511
hydrolase
39-403 1.02e-82

hydrolase


Pssm-ID: 215282 [Multi-domain]  Cd Length: 388  Bit Score: 258.56  E-value: 1.02e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663   39 GFSVAyAFYYLSSIAKKPQL-VTGGESfsRFLQDHCPVVTETYYPTVWCWEGRGQTLLRPFITSKPPVQYRNELIKTADG 117
Cdd:PLN02511   5 HFSVA-AILAPGQTREHSSLeVIGGGR--DSFLPKFKSLERPYDAFPLLGNRHVETIFASFFRSLPAVRYRRECLRTPDG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663  118 GQISLDWFDNDNSTCYMDAstrPTILLLPGLTGTSKESYILHMIHLSEELGYRCVVFNNRGVAGENLLTPRTYCCANTED 197
Cdd:PLN02511  82 GAVALDWVSGDDRALPADA---PVLILLPGLTGGSDDSYVRHMLLRARSKGWRVVVFNSRGCADSPVTTPQFYSASFTGD 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663  198 LETVIHHVHSLYPSAPFLAAGVSMGGMLLLNYLGKIGSKTPLMAAATFSVGWNTFACSESLEKPLNwLLFNYYLTTCLQS 277
Cdd:PLN02511 159 LRQVVDHVAGRYPSANLYAAGWSLGANILVNYLGEEGENCPLSGAVSLCNPFDLVIADEDFHKGFN-NVYDKALAKALRK 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663  278 SVNKHRHMFV---KQVDMDHVMKAKSIREFDKRFTSVMFGYQTIDDYYTDASPSPRLKSVGIPVLCLNSVDDVFSPSHAI 354
Cdd:PLN02511 238 IFAKHALLFEglgGEYNIPLVANAKTVRDFDDGLTRVSFGFKSVDAYYSNSSSSDSIKHVRVPLLCIQAANDPIAPARGI 317
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 23397663  355 PIETAKQNPNVALVLTSYGGHIGFLEGI-WPRQSTYMDRVFKQFVQAMVE 403
Cdd:PLN02511 318 PREDIKANPNCLLIVTPSGGHLGWVAGPeAPFGAPWTDPVVMEFLEALEE 367
PRK10985 PRK10985
putative hydrolase; Provisional
92-383 2.88e-38

putative hydrolase; Provisional


Pssm-ID: 182883  Cd Length: 324  Bit Score: 140.48  E-value: 2.88e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663   92 QTLLRPFITSKP---PVQYRNELiktADGGQISLDWFDNDNstcymDASTRPTILLLPGLTGTSKESYILHMIHLSEELG 168
Cdd:PRK10985  16 QTLLPRLIRRKVlftPYWQRLEL---PDGDFVDLAWSEDPA-----QARHKPRLVLFHGLEGSFNSPYAHGLLEAAQKRG 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663  169 YRCVVFNNRGVAGENLLTPRTYCCANTEDLETVIHHVHSLYPSAPFLAAGVSMGGMLLLNYLGKIGSKTPLMAAATFSVG 248
Cdd:PRK10985  88 WLGVVMHFRGCSGEPNRLHRIYHSGETEDARFFLRWLQREFGHVPTAAVGYSLGGNMLACLLAKEGDDLPLDAAVIVSAP 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663  249 WNTFACSESLEKPLNWLLFNYYLTTCLQSSVNKHrHMFVKQ--VDMDHVMKAKSIREFDKRFTSVMFGYQTIDDYYTDAS 326
Cdd:PRK10985 168 LMLEACSYRMEQGFSRVYQRYLLNLLKANAARKL-AAYPGTlpINLAQLKSVRRLREFDDLITARIHGFADAIDYYRQCS 246
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 23397663  327 PSPRLKSVGIPVLCLNSVDDVFSPSHAIPiETAKQNPNVALVLTSYGGHIGFLEGIW 383
Cdd:PRK10985 247 ALPLLNQIRKPTLIIHAKDDPFMTHEVIP-KPESLPPNVEYQLTEHGGHVGFVGGTL 302
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
140-381 9.05e-11

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 61.75  E-value: 9.05e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663   140 PTILLLPGLTGTSKESYILhMIHLSEeLGYRCVVFNNRGVA-GENLLTPRTYCcanTEDLETVIHHVHSLYPSAPFLAAG 218
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKL-APALAR-DGFRVIALDLRGFGkSSRPKAQDDYR---TDDLAEDLEYILEALGLEKVNLVG 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663   219 VSMGGMLLLNYLGKIGSKtplMAAATFSVGWNTFACSESLEKPLNWLLFNYYLTT---CLQSSVNKHRHMFVKQVDMDHV 295
Cdd:pfam00561  76 HSMGGLIALAYAAKYPDR---VKALVLLGALDPPHELDEADRFILALFPGFFDGFvadFAPNPLGRLVAKLLALLLLRLR 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663   296 MKaKSIREFDKRFTSV-----MFGYQTIDDY---YTDASPSPRLKSVGIPVLCLNSVDDVFSPSHAIPiETAKQNPNVAL 367
Cdd:pfam00561 153 LL-KALPLLNKRFPSGdyalaKSLVTGALLFietWSTELRAKFLGRLDEPTLIIWGDQDPLVPPQALE-KLAQLFPNARL 230
                         250
                  ....*....|....
gi 23397663   368 VLTSYGGHIGFLEG 381
Cdd:pfam00561 231 VVIPDAGHFAFLEG 244
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
112-232 3.68e-08

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 53.47  E-value: 3.68e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663 112 IKTADGGQISLDWFDNDnstcymdASTRPTILLLPGLTGTSKesyilHMIHLSEEL---GYRCVVFNNRG-----VAGEN 183
Cdd:COG2267   8 LPTRDGLRLRGRRWRPA-------GSPRGTVVLVHGLGEHSG-----RYAELAEALaaaGYAVLAFDLRGhgrsdGPRGH 75
                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*....
gi 23397663 184 LLTPRTYccanTEDLETVIHHVHSLyPSAPFLAAGVSMGGMLLLNYLGK 232
Cdd:COG2267  76 VDSFDDY----VDDLRAALDALRAR-PGLPVVLLGHSMGGLIALLYAAR 119
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
112-399 6.39e-07

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 50.02  E-value: 6.39e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663 112 IKTADGGQISLDWFDNDnstcymDASTRPTILLLPGLTGTSKESYILHMIHLSEeLGYRCVVFNNRGVaGEnllTPRTYC 191
Cdd:COG1506   2 FKSADGTTLPGWLYLPA------DGKKYPVVVYVHGGPGSRDDSFLPLAQALAS-RGYAVLAPDYRGY-GE---SAGDWG 70
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663 192 CANTEDLETVIHHV--HSLYPSAPFLAAGVSMGGMLLlnylgkigsktpLMAAATFSvgwNTFACseslekplnwllfny 269
Cdd:COG1506  71 GDEVDDVLAAIDYLaaRPYVDPDRIGIYGHSYGGYMA------------LLAAARHP---DRFKA--------------- 120
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663 270 yltTCLQSSVnkhrhmfvkqVDMDHVMkaKSIREFDKRFtsvMFGYQTIDDYYTDASPSPRLKSVGIPVLCLNS-VDDVF 348
Cdd:COG1506 121 ---AVALAGV----------SDLRSYY--GTTREYTERL---MGGPWEDPEAYAARSPLAYADKLKTPLLLIHGeADDRV 182
                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|...
gi 23397663 349 SPSHAIPIETA--KQNPNVALVLTSYGGHiGFLEGIWPRQSTYMDRVFKQFVQ 399
Cdd:COG1506 183 PPEQAERLYEAlkKAGKPVELLVYPGEGH-GFSGAGAPDYLERILDFLDRHLK 234
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
142-253 5.97e-05

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 44.00  E-value: 5.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663   142 ILLLPGLTgtskesyiLHMIHLSEEL--GYRCVVFNNRGVaGENLLTPRTYccantEDLETVIHHVHSLYPSAPFLAAGV 219
Cdd:pfam12697   1 VVLVHGAG--------LSAAPLAALLaaGVAVLAPDLPGH-GSSSPPPLDL-----ADLADLAALLDELGAARPVVLVGH 66
                          90       100       110
                  ....*....|....*....|....*....|....
gi 23397663   220 SMGGMLLLNYLGKIGSKTPLMAAATFSVGWNTFA 253
Cdd:pfam12697  67 SLGGAVALAAAAAALVVGVLVAPLAAPPGLLAAL 100
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
133-380 4.87e-04

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 41.14  E-value: 4.87e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663 133 YMDA-STRPTILLLPGLTGTSkESYILHMIHLSEelGYRCVVFNNRGV----AGENLLTPRTYCcantEDLETVIHHVHS 207
Cdd:COG0596  16 YREAgPDGPPVVLLHGLPGSS-YEWRPLIPALAA--GYRVIAPDLRGHgrsdKPAGGYTLDDLA----DDLAALLDALGL 88
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663 208 lypsAPFLAAGVSMGGMLLLNYlgkigsktplmaAATFsvgwntfacSESLEKplnwllfnyyLTtclqsSVNKHRHMFV 287
Cdd:COG0596  89 ----ERVVLVGHSMGGMVALEL------------AARH---------PERVAG----------LV-----LVDEVLAALA 128
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23397663 288 KQVDMDhvmkAKSIREFDKRFTSVmfgyqtiddyyTDASPSPRLKSVGIPVLCLNSVDDVFSPShAIPIETAKQNPNVAL 367
Cdd:COG0596 129 EPLRRP----GLAPEALAALLRAL-----------ARTDLRERLARITVPTLVIWGEKDPIVPP-ALARRLAELLPNAEL 192
                       250
                ....*....|...
gi 23397663 368 VLTSYGGHIGFLE 380
Cdd:COG0596 193 VVLPGAGHFPPLE 205
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH