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Conserved domains on  [gi|24657342|ref|NP_647870|]
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uncharacterized protein Dmel_CG15005 [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Mucin-like pfam16058
Mucin-like; This region is found repeated at the C-terminus (C-tail) of bile salt-activated ...
 307-399 4.47e-12

Mucin-like; This region is found repeated at the C-terminus (C-tail) of bile salt-activated lipase, where is O-glycosylated. This region is composed of biased amino acid composition that is likely to be disordered. The region contains many repeats of an approximately 11 residue degenerate repeat.


:

Pssm-ID: 464997 [Multi-domain]  Cd Length: 94  Bit Score: 62.82  E-value: 4.47e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   307 PPTNSYAPPQHPSSSYDQPPQHPSSSYDQPPQHPPPSYSQPPQHPSSSYDQPAQHPSSSYDQPPKHPSSSYEQPPQHPSS 386
Cdd:pfam16058   1 PSSSITEPPRDPSGSYGEPPRAPSSSYTEPQRDPSSSITEPPADPSSSYTEPPRDPSGSYTEPQRDPSSSSTEPQRDPSS 80

                          90
                  ....*....|...
gi 24657342   387 SYDQPPQHPSSSY 399
Cdd:pfam16058  81 SITEPPRDPSGSY 93
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 202-565 1.64e-07

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 55.33  E-value: 1.64e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   202 PDAPAPVPSYPHQDLPAPDSYSIYEQKIPNVGYHQNFAEPPKHPPKHGSINNPNFEIAYSPPAfeiSTSYQSNHQQSYVP 281
Cdd:PHA03247 2769 PAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPP---TSAQPTAPPPPPGP 2845

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   282 PHPPSSHDGFAEPPSNNYVKPPPQHPPTNSYAPPQHPSSSYDQPP-QHPSSSYDQPPqhpppsysqppqhpsssydqpaq 360
Cdd:PHA03247 2846 PPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAvSRSTESFALPP----------------------- 2902

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   361 hpsssyDQPPKHPSSSYEQPPQhpsssydQPPQHPSSSYDQPPEEHPSSYQHPPTSTYDQAPQHPPSNYVSSdshsinty 440
Cdd:PHA03247 2903 ------DQPERPPQPQAPPPPQ-------PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQ-------- 2961

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   441 PQDDYSPPSQelplnphHKFPSFDFPKSSYEVPIydPVPFEASNRDEQESYPPILASSPDLNEitsdahaagsskrrkrk 520
Cdd:PHA03247 2962 PWLGALVPGR-------VAVPRFRVPQPAPSREA--PASSTPPLTGHSLSRVSSWASSLALHE----------------- 3015

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 24657342   521 rKPSPGVVPAKHTLDVPELQQAYDADSHL----GESHESNADTDANSSH 565
Cdd:PHA03247 3016 -ETDPPPVSLKQTLWPPDDTEDSDADSLFdsdsERSDLEALDPLPPEPH 3063
 
Name Accession Description Interval E-value
Mucin-like pfam16058
Mucin-like; This region is found repeated at the C-terminus (C-tail) of bile salt-activated ...
 307-399 4.47e-12

Mucin-like; This region is found repeated at the C-terminus (C-tail) of bile salt-activated lipase, where is O-glycosylated. This region is composed of biased amino acid composition that is likely to be disordered. The region contains many repeats of an approximately 11 residue degenerate repeat.


Pssm-ID: 464997 [Multi-domain]  Cd Length: 94  Bit Score: 62.82  E-value: 4.47e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   307 PPTNSYAPPQHPSSSYDQPPQHPSSSYDQPPQHPPPSYSQPPQHPSSSYDQPAQHPSSSYDQPPKHPSSSYEQPPQHPSS 386
Cdd:pfam16058   1 PSSSITEPPRDPSGSYGEPPRAPSSSYTEPQRDPSSSITEPPADPSSSYTEPPRDPSGSYTEPQRDPSSSSTEPQRDPSS 80

                          90
                  ....*....|...
gi 24657342   387 SYDQPPQHPSSSY 399
Cdd:pfam16058  81 SITEPPRDPSGSY 93
PHA03247 PHA03247
large tegument protein UL36; Provisional
 202-565 1.64e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 55.33  E-value: 1.64e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   202 PDAPAPVPSYPHQDLPAPDSYSIYEQKIPNVGYHQNFAEPPKHPPKHGSINNPNFEIAYSPPAfeiSTSYQSNHQQSYVP 281
Cdd:PHA03247 2769 PAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPP---TSAQPTAPPPPPGP 2845

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   282 PHPPSSHDGFAEPPSNNYVKPPPQHPPTNSYAPPQHPSSSYDQPP-QHPSSSYDQPPqhpppsysqppqhpsssydqpaq 360
Cdd:PHA03247 2846 PPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAvSRSTESFALPP----------------------- 2902

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   361 hpsssyDQPPKHPSSSYEQPPQhpsssydQPPQHPSSSYDQPPEEHPSSYQHPPTSTYDQAPQHPPSNYVSSdshsinty 440
Cdd:PHA03247 2903 ------DQPERPPQPQAPPPPQ-------PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQ-------- 2961

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   441 PQDDYSPPSQelplnphHKFPSFDFPKSSYEVPIydPVPFEASNRDEQESYPPILASSPDLNEitsdahaagsskrrkrk 520
Cdd:PHA03247 2962 PWLGALVPGR-------VAVPRFRVPQPAPSREA--PASSTPPLTGHSLSRVSSWASSLALHE----------------- 3015

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 24657342   521 rKPSPGVVPAKHTLDVPELQQAYDADSHL----GESHESNADTDANSSH 565
Cdd:PHA03247 3016 -ETDPPPVSLKQTLWPPDDTEDSDADSLFdsdsERSDLEALDPLPPEPH 3063
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 225-462 1.77e-07

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 54.66  E-value: 1.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   225 YEQKIPNVGYHQNFAEPPKHPPKHGSINNPNFEIAYSPpafeISTSYQSNHQQSYVPP-HPPSSHDGFAEPPSnnyvkPP 303
Cdd:pfam09770 102 FNRQQPAARAAQSSAQPPASSLPQYQYASQQSQQPSKP----VRTGYEKYKEPEPIPDlQVDASLWGVAPKKA-----AA 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   304 PQHPPTNSYAPPQHPSSSY----------------DQPPQHPSSSYDQPPQHPPPSYSQPPQHPSSSYDQPAQHPSSSYD 367
Cdd:pfam09770 173 PAPAPQPAAQPASLPAPSRkmmsleeveaamraqaKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQ 252

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   368 QPPKHPSSSYEQPPQHPSSSYDQPPQHPSSSYDQPPEEHPSSYQHPPTstydQAPQHPpsNYVSSDSHSINTYPQddysP 447
Cdd:pfam09770 253 PQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPT----QILQNP--NRLSAARVGYPQNPQ----P 322

                         250
                  ....*....|....*
gi 24657342   448 PSQELPLNPHHKFPS 462
Cdd:pfam09770 323 GVQPAPAHQAHRQQG 337
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 303-429 4.18e-07

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 53.94  E-value: 4.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   303 PPQHPPTNSYAPPQHPSSSYDQPPQHPSSSYDQPPQHPPPSYSQPPQHPSSSYDQPA-----QHPSSSYDQPPKHPSSSY 377
Cdd:PRK10263  377 PEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYyapapEQPVAGNAWQAEEQQSTF 456

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 24657342   378 E-QPPQHPSSSYDQPPQhPSSSYDQPPEEHPSSYQHPPTSTYDQAPQHPPSNY 429
Cdd:PRK10263  457 ApQSTYQTEQTYQQPAA-QEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYY 508
COG5028 COG5028
Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking ...
 234-376 8.72e-03

Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion];


Pssm-ID: 227361 [Multi-domain]  Cd Length: 861  Bit Score: 39.39  E-value: 8.72e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342 234 YHQNFAEPPKHPPKHGSINNPNFEIAYSPPAFEISTSYQSNHQQsyvPPHPPSSHDGFAEPPSNNYVKP-PPQHPPTNSY 312
Cdd:COG5028  16 VHTGAASSKKSARPHRAYANFSAGQMGMPPYTTPPLQQQSRRQI---DQAATAMHNTGANNPAPSVMSPaFQSQQKFSSP 92

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24657342 313 APPQHPSSSYDQP--PQHPSSSY-DQPPQHPPPSYSQPPQHPSSSYDqpaQHPSSSYDQPPKHPSSS 376
Cdd:COG5028  93 YGGSMADGTAPKPtnPLVPVDLFeDQPPPISDLFLPPPPIVPPLTTN---FVGSEQSNCSPKYVRST 156
 
Name Accession Description Interval E-value
Mucin-like pfam16058
Mucin-like; This region is found repeated at the C-terminus (C-tail) of bile salt-activated ...
 307-399 4.47e-12

Mucin-like; This region is found repeated at the C-terminus (C-tail) of bile salt-activated lipase, where is O-glycosylated. This region is composed of biased amino acid composition that is likely to be disordered. The region contains many repeats of an approximately 11 residue degenerate repeat.


Pssm-ID: 464997 [Multi-domain]  Cd Length: 94  Bit Score: 62.82  E-value: 4.47e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   307 PPTNSYAPPQHPSSSYDQPPQHPSSSYDQPPQHPPPSYSQPPQHPSSSYDQPAQHPSSSYDQPPKHPSSSYEQPPQHPSS 386
Cdd:pfam16058   1 PSSSITEPPRDPSGSYGEPPRAPSSSYTEPQRDPSSSITEPPADPSSSYTEPPRDPSGSYTEPQRDPSSSSTEPQRDPSS 80

                          90
                  ....*....|...
gi 24657342   387 SYDQPPQHPSSSY 399
Cdd:pfam16058  81 SITEPPRDPSGSY 93
Mucin-like pfam16058
Mucin-like; This region is found repeated at the C-terminus (C-tail) of bile salt-activated ...
 318-410 1.04e-09

Mucin-like; This region is found repeated at the C-terminus (C-tail) of bile salt-activated lipase, where is O-glycosylated. This region is composed of biased amino acid composition that is likely to be disordered. The region contains many repeats of an approximately 11 residue degenerate repeat.


Pssm-ID: 464997 [Multi-domain]  Cd Length: 94  Bit Score: 55.89  E-value: 1.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   318 PSSSYDQPPQHPSSSYDQPPQHPPPSYSQPPQHPSSSYDQPAQHPSSSYDQPPKHPSSSYEQPPQHPSSSYDQPPQHPSS 397
Cdd:pfam16058   1 PSSSITEPPRDPSGSYGEPPRAPSSSYTEPQRDPSSSITEPPADPSSSYTEPPRDPSGSYTEPQRDPSSSSTEPQRDPSS 80

                          90
                  ....*....|...
gi 24657342   398 SYDQPPEEHPSSY 410
Cdd:pfam16058  81 SITEPPRDPSGSY 93
Mucin-like pfam16058
Mucin-like; This region is found repeated at the C-terminus (C-tail) of bile salt-activated ...
 302-388 3.34e-08

Mucin-like; This region is found repeated at the C-terminus (C-tail) of bile salt-activated lipase, where is O-glycosylated. This region is composed of biased amino acid composition that is likely to be disordered. The region contains many repeats of an approximately 11 residue degenerate repeat.


Pssm-ID: 464997 [Multi-domain]  Cd Length: 94  Bit Score: 51.65  E-value: 3.34e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   302 PPPQHPPTNSY-APPQHPSSSYDQPPQHPSSSYDQPPQHPPPSYSQPPQHPSSSYDQPAQHPSSSYDQPPKHPSSSYEQP 380
Cdd:pfam16058   6 TEPPRDPSGSYgEPPRAPSSSYTEPQRDPSSSITEPPADPSSSYTEPPRDPSGSYTEPQRDPSSSSTEPQRDPSSSITEP 85


                  ....*...
gi 24657342   381 PQHPSSSY 388
Cdd:pfam16058  86 PRDPSGSY 93
PHA03247 PHA03247
large tegument protein UL36; Provisional
 202-565 1.64e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 55.33  E-value: 1.64e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   202 PDAPAPVPSYPHQDLPAPDSYSIYEQKIPNVGYHQNFAEPPKHPPKHGSINNPNFEIAYSPPAfeiSTSYQSNHQQSYVP 281
Cdd:PHA03247 2769 PAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPP---TSAQPTAPPPPPGP 2845

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   282 PHPPSSHDGFAEPPSNNYVKPPPQHPPTNSYAPPQHPSSSYDQPP-QHPSSSYDQPPqhpppsysqppqhpsssydqpaq 360
Cdd:PHA03247 2846 PPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAvSRSTESFALPP----------------------- 2902

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   361 hpsssyDQPPKHPSSSYEQPPQhpsssydQPPQHPSSSYDQPPEEHPSSYQHPPTSTYDQAPQHPPSNYVSSdshsinty 440
Cdd:PHA03247 2903 ------DQPERPPQPQAPPPPQ-------PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQ-------- 2961

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   441 PQDDYSPPSQelplnphHKFPSFDFPKSSYEVPIydPVPFEASNRDEQESYPPILASSPDLNEitsdahaagsskrrkrk 520
Cdd:PHA03247 2962 PWLGALVPGR-------VAVPRFRVPQPAPSREA--PASSTPPLTGHSLSRVSSWASSLALHE----------------- 3015

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 24657342   521 rKPSPGVVPAKHTLDVPELQQAYDADSHL----GESHESNADTDANSSH 565
Cdd:PHA03247 3016 -ETDPPPVSLKQTLWPPDDTEDSDADSLFdsdsERSDLEALDPLPPEPH 3063
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 225-462 1.77e-07

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 54.66  E-value: 1.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   225 YEQKIPNVGYHQNFAEPPKHPPKHGSINNPNFEIAYSPpafeISTSYQSNHQQSYVPP-HPPSSHDGFAEPPSnnyvkPP 303
Cdd:pfam09770 102 FNRQQPAARAAQSSAQPPASSLPQYQYASQQSQQPSKP----VRTGYEKYKEPEPIPDlQVDASLWGVAPKKA-----AA 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   304 PQHPPTNSYAPPQHPSSSY----------------DQPPQHPSSSYDQPPQHPPPSYSQPPQHPSSSYDQPAQHPSSSYD 367
Cdd:pfam09770 173 PAPAPQPAAQPASLPAPSRkmmsleeveaamraqaKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQ 252

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   368 QPPKHPSSSYEQPPQHPSSSYDQPPQHPSSSYDQPPEEHPSSYQHPPTstydQAPQHPpsNYVSSDSHSINTYPQddysP 447
Cdd:pfam09770 253 PQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPT----QILQNP--NRLSAARVGYPQNPQ----P 322

                         250
                  ....*....|....*
gi 24657342   448 PSQELPLNPHHKFPS 462
Cdd:pfam09770 323 GVQPAPAHQAHRQQG 337
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 303-429 4.18e-07

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 53.94  E-value: 4.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   303 PPQHPPTNSYAPPQHPSSSYDQPPQHPSSSYDQPPQHPPPSYSQPPQHPSSSYDQPA-----QHPSSSYDQPPKHPSSSY 377
Cdd:PRK10263  377 PEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYyapapEQPVAGNAWQAEEQQSTF 456

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 24657342   378 E-QPPQHPSSSYDQPPQhPSSSYDQPPEEHPSSYQHPPTSTYDQAPQHPPSNY 429
Cdd:PRK10263  457 ApQSTYQTEQTYQQPAA-QEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYY 508
PTZ00441 PTZ00441
sporozoite surface protein 2 (SSP2); Provisional
 203-420 2.99e-06

sporozoite surface protein 2 (SSP2); Provisional


Pssm-ID: 240420 [Multi-domain]  Cd Length: 576  Bit Score: 50.73  E-value: 2.99e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342  203 DAPAPVPSYPHQDLPAPDSYsiyEQKIPNvgYHQNFAEP-----PKHPPKHGSINNPNfEIAYSPPAFEistsyqSNHQQ 277
Cdd:PTZ00441 290 PVPAPVPPTPEDDNPRPTDD---EFAVPN--FNEGLDVPdnpqdPVPPPNEGKDGNPN-EENLFPPGDD------EVPDE 357

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342  278 SYVPPHPPSSHDGFAEPPSNNYVKPPpqhPPTNSYAPPQHPSSSYDQPPQHPSSSYDQPPQHPPPSYSQPPQHPSSSYDQ 357
Cdd:PTZ00441 358 SNVPPNPPNVPGGSNSEFSSDVENPP---NPPNPDIPEQEPNIPEDSNKEVPEDVPMEPEDDRDNNFNEPKKPENKGDGQ 434

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24657342  358 PAQHPSSSYDQPPKHPSSSYEQPPQHPSSSYDQ--PPQHPSSSYDQPPEEHPSSYQHPPTSTYDQ 420
Cdd:PTZ00441 435 NEPVIPKPLDNERDQSNKNKQVNPGNRHNSEDRytRPHGRNNENRNYNNKNSDIPKHPERSEHEQ 499
PHA03247 PHA03247
large tegument protein UL36; Provisional
 161-500 1.16e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.17  E-value: 1.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   161 VPHQQYGLPPVQQSFQPDHSFTTHYEPPPAPAHPPATRYGVPDAPAPVPSYPHQDLPAPDSYSIYEQKI----------- 229
Cdd:PHA03247 2600 APVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARrlgraaqassp 2679

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   230 ----------PNVGYHQNFAEPPKHPPKHGSINNPNFEIAYSPPAfeiSTSYQSNHQQSYVPPHPPSSHDGFAEPPSNNy 299
Cdd:PHA03247 2680 pqrprrraarPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPG---PAAARQASPALPAAPAPPAVPAGPATPGGPA- 2755

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   300 vkpPPQHPPTNSYAPPQHPSSSydqPPQHPSSSYDQPPQHPPPSYSQPPQHPSSSYDQPAQHPSSSYDQPPKHPSSSYEQ 379
Cdd:PHA03247 2756 ---RPARPPTTAGPPAPAPPAA---PAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLP 2829

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   380 PPQHPSSSYDQPPQHPSSSYDQ---------PPEEHPSSYQHPPTSTydqAPQHPPSNYVSSdshsintyPQDDYSPPSQ 450
Cdd:PHA03247 2830 PPTSAQPTAPPPPPGPPPPSLPlggsvapggDVRRRPPSRSPAAKPA---APARPPVRRLAR--------PAVSRSTESF 2898

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 24657342   451 ELPLNPHHKFPSFDFPKSSYEVPIYDPVPFEASNRDEQESYPPILASSPD 500
Cdd:PHA03247 2899 ALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTD 2948
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 280-452 1.88e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 48.06  E-value: 1.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342  280 VPPHPPSSHDGFAEPPSNNyvkPPPQHPPTNSYAPPQHPSSSYDQPPQHPSSSYDQPPQhPPPSYSQPPQHPSSSYDQPA 359
Cdd:PRK07764 625 AAPAPAGAAAAPAEASAAP---APGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAA-PPPAPAPAAPAAPAGAAPAQ 700

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342  360 QHPSSSYDQPPKHPSSSYEQPPQH-------PSSSYDQPPQHPSSSYDQPPEEHP-SSYQHPPTSTYDQAPQHPPsnyVS 431
Cdd:PRK07764 701 PAPAPAATPPAGQADDPAAQPPQAaqgasapSPAADDPVPLPPEPDDPPDPAGAPaQPPPPPAPAPAAAPAAAPP---PS 777

                        170       180
                 ....*....|....*....|.
gi 24657342  432 SDSHSINTYPQDDYSPPSQEL 452
Cdd:PRK07764 778 PPSEEEEMAEDDAPSMDDEDR 798
PHA03247 PHA03247
large tegument protein UL36; Provisional
 241-530 2.09e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 2.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   241 PPKHPPKHGSINNPNFEIAYSPPafeiSTSYQSNHQQSYVPPHPPSSHDGfAEPPSNNYVKPPPQHPPTNSYAPPQHPSS 320
Cdd:PHA03247 2556 PPAAPPAAPDRSVPPPRPAPRPS----EPAVTSRARRPDAPPQSARPRAP-VDDRGDPRGPAPPSPLPPDTHAPDPPPPS 2630

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   321 SYDQPPQHPSSSYDQPPQHPPPSYSQPPQHPSSSYDQPAQHPSSSYDQPPKHPSSSYEQPPQHPSSSYDQPPQHPSSSYD 400
Cdd:PHA03247 2631 PSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEP 2710

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   401 QPPEEHPSSYQHPPTSTYDQAPQHPPSNYVSSDSHSINTYPQDDYSPPSQELPLNPHHKFPSFDFPKSSyevPIYDPVPF 480
Cdd:PHA03247 2711 APHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGP---PRRLTRPA 2787

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 24657342   481 EASNRDEQESYPPILASSPDLNEITSDAHAAGSSKRRKRKRKPSPGVVPA 530
Cdd:PHA03247 2788 VASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT 2837
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 266-407 4.29e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 47.39  E-value: 4.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   266 EISTSYQSNHQQSYVPPHP----PSSHDGFAEPPSNNYVKPPPQHP-------PTNSYAPPQHPSSSYDQP--PQHPSSS 332
Cdd:PRK10263  698 ELARQFAQTQQQRYSGEQPaganPFSLDDFEFSPMKALLDDGPHEPlftpivePVQQPQQPVAPQQQYQQPqqPVAPQPQ 777

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24657342   333 YDQPPQHPPPSYSQPPQHPSSSYDQPAQHPsssydQPPKHPSSSYEQP--PQHPSSSYDQpPQHPSSSYDQPPEEHP 407
Cdd:PRK10263  778 YQQPQQPVAPQPQYQQPQQPVAPQPQYQQP-----QQPVAPQPQYQQPqqPVAPQPQYQQ-PQQPVAPQPQDTLLHP 848
dnaA PRK14086
chromosomal replication initiator protein DnaA;
269-463 5.04e-05

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 46.74  E-value: 5.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342  269 TSYQSNHQQSYVPPHPPSSHDGFAEPPSNNYVKPPPQHP--PTnsyAPPQHPSssyDQPPQHPSSsYDQPPqhpppsYSQ 346
Cdd:PRK14086  99 PPHARRTSEPELPRPGRRPYEGYGGPRADDRPPGLPRQDqlPT---ARPAYPA---YQQRPEPGA-WPRAA------DDY 165

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342  347 PPQHPSSSYDQPAQHPSSSYDQPpkhPSSSYEQPPQHPSSSYDQP---PQHPSSSYDQP-------PEEHPSSYQHPPTS 416
Cdd:PRK14086 166 GWQQQRLGFPPRAPYASPASYAP---EQERDREPYDAGRPEYDQRrrdYDHPRPDWDRPrrdrtdrPEPPPGAGHVHRGG 242

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 24657342  417 tydQAPQHPPSNYVSSDSHSINTY----PQDDYSPPSQELPLNPHHKFPSF 463
Cdd:PRK14086 243 ---PGPPERDDAPVVPIRPSAPGPlaaqPAPAPGPGEPTARLNPKYTFDTF 290
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 205-336 5.49e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 47.00  E-value: 5.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   205 PAPVPSYPHQDL-PAPDSYSIYEQKI-PNVGYHQNFAEP-PKHPPKHGSINNPNFEIAYSPPAFEISTSYQSNHQQsyvP 281
Cdd:PRK10263  362 PVPGPQTGEPVIaPAPEGYPQQSQYAqPAVQYNEPLQQPvQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPA---P 438

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 24657342   282 PHPPSSHDGFAEPPSNNYvKPPPQHPPTNSYAPPQHPSSSYDQPPQHPSSSYDQP 336
Cdd:PRK10263  439 EQPVAGNAWQAEEQQSTF-APQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEP 492
dnaA PRK14086
chromosomal replication initiator protein DnaA;
300-493 7.54e-05

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 45.97  E-value: 7.54e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342  300 VKPPPQHPPTNSYAPPQHPSSSYDQPPQHPSSSYDQPPQHPPPSYSQPPQHPSssYDQPAQHPsssydQPPKHPSSSYEQ 379
Cdd:PRK14086  93 GEPAPPPPHARRTSEPELPRPGRRPYEGYGGPRADDRPPGLPRQDQLPTARPA--YPAYQQRP-----EPGAWPRAADDY 165

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342  380 PPQHPSSSYDQPPQHPSSSYDQPPEEH---PSSYQHPPTSTYDQAPQHPPSNYvssdshsinTYPQDDYSPPSQELPL-- 454
Cdd:PRK14086 166 GWQQQRLGFPPRAPYASPASYAPEQERdrePYDAGRPEYDQRRRDYDHPRPDW---------DRPRRDRTDRPEPPPGag 236

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 24657342  455 NPHHKFPSFDFPKSSYEVPIYDPVPFEASNRDEQESYPP 493
Cdd:PRK14086 237 HVHRGGPGPPERDDAPVVPIRPSAPGPLAAQPAPAPGPG 275
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 203-403 3.47e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 44.31  E-value: 3.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   203 DAPAPVPSYPHQDlPAPDSYSIYEQKIPNVgyhqNFAEPPKHPPKHGsinnpnfeiaYSP-PAFEISTSYQSNHQQSYVP 281
Cdd:PRK10263  338 EPVTQTPPVASVD-VPPAQPTVAWQPVPGP----QTGEPVIAPAPEG----------YPQqSQYAQPAVQYNEPLQQPVQ 402

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   282 PHPPSSHDGFAEPPSNNYVKPPPQHPPTNSYAPPQHPSSSYDQPPQHPSSSYDQPPQhpppsysqppqhpsssydqPAQH 361
Cdd:PRK10263  403 PQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQ-------------------STYQ 463

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 24657342   362 PSSSYDQPPKHPSSSYEQPPQHPSSSYDQPPQHPSSSYDQPP 403
Cdd:PRK10263  464 TEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPP 505
PHA03247 PHA03247
large tegument protein UL36; Provisional
 168-456 7.37e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 7.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   168 LPPVQQSFQPDHSFTTHYEPPPAPAHPPATRYGVPDAPaPVPSYPHQDLPAPDSYSIYEQKIPNVGYHQNFAEPPKHPPK 247
Cdd:PHA03247 2555 LPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAP-PQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSP 2633

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   248 HGSINNPNFEIAYSPPAFEIS------------TSYQSNHQQSYVPPH---PPSSHDGFAepPSNNYVKPPPQHPPTNSY 312
Cdd:PHA03247 2634 AANEPDPHPPPTVPPPERPRDdpapgrvsrprrARRLGRAAQASSPPQrprRRAARPTVG--SLTSLADPPPPPPTPEPA 2711

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   313 APPQHPSSSYDQPPQHPSSSYDQPPQHPPPSYSQPPQHPSSSYDQPAQHPSSSYDQPPKHPSSSYEQPPQH--------- 383
Cdd:PHA03247 2712 PHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRltrpavasl 2791

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   384 ---------PSSSYDQPPQHPSSSYDQPPEEHPSSYQHPPTSTYDQAPQHPPSNYVSSDSHSINTYPQDDYS--PPSQEL 452
Cdd:PHA03247 2792 sesreslpsPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRrrPPSRSP 2871


                  ....
gi 24657342   453 PLNP 456
Cdd:PHA03247 2872 AAKP 2875
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 204-469 1.61e-03

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 42.06  E-value: 1.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   204 APAPVPSYPH-QDLPAPDSYSIYEQKIPNVGYHQNFAEPPK-HPPKHGSINNPNFEIAYSPPAFEisTSYQSNHQQSYVP 281
Cdd:pfam03154 196 TAGPTPSAPSvPPQGSPATSQPPNQTQSTAAPHTLIQQTPTlHPQRLPSPHPPLQPMTQPPPPSQ--VSPQPLPQPSLHG 273

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   282 PHPPSSHDGFAEPPSNNYVKPPPQHPPTNSYAPPQHPSSSYDQPPQHPSSSYDQPPQHPPPSYSQPPQH---PSSSYDQP 358
Cdd:pfam03154 274 QMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPPREqplPPAPLSMP 353

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   359 AQHPSSSYDQPPKHPSSSYEQPP--------QHPSSSYDQPPQHPSSSYD--QPPEEHPSSYQHPPTSTYDQAPQHPPSN 428
Cdd:pfam03154 354 HIKPPPTTPIPQLPNPQSHKHPPhlsgpspfQMNSNLPPPPALKPLSSLSthHPPSAHPPPLQLMPQSQQLPPPPAQPPV 433

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 24657342   429 YVSSDSHSIntyPQDDYSPPSQELPLNPHHKFPSFDFPKSS 469
Cdd:pfam03154 434 LTQSQSLPP---PAASHPPTSGLHQVPSQSPFPQHPFVPGG 471
PHA03160 PHA03160
hypothetical protein; Provisional
 325-446 1.76e-03

hypothetical protein; Provisional


Pssm-ID: 165431  Cd Length: 499  Bit Score: 41.61  E-value: 1.76e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342  325 PPQHPSSSYDQPPQHpppsysqppqhpsSSYDQPAQHPSSSYDQPPKHPSSSYEQPPQHPSSSYDQPPQHPSssYDQPPE 404
Cdd:PHA03160 380 IPHHFSNPYSFDPGH-------------APFFRYAPYGAPKNDHHLLPPLACSQQLPMQPLHVQQAPMQAPH--VAPPPM 444

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 24657342  405 EHPSSYQHPPTSTYDQAPQHPPSNYVSSDSHSINTYPQDDYS 446
Cdd:PHA03160 445 QPPHVQQPRVLPSTDGASNEAPKPSAQEPVHIDASFAQDPVS 486
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 202-525 2.24e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 41.70  E-value: 2.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   202 PDAPAPVPSYPHQDLPAPDSYSIYEQKIPNVGYHQNFAEPPKHPPKHGSINNPnfeiaysPPAFEISTSYQSNHQQSYVP 281
Cdd:PHA03307   28 PGDAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAP-------ANESRSTPTWSLSTLAPASP 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   282 PHPPSSHDGFAEPPSnnyvkPPPQHPPTNSYAPPQHPSSSYDQPPQHPSSSYDQPPQHPPPSYSQPPQHPSSSYDQPAqh 361
Cdd:PHA03307  101 AREGSPTPPGPSSPD-----PPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAA-- 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   362 PSSSYDQPPKHPSSsyeqPPQHPSSSYDQPPQHPSSSYDQPPEEHPSSYQHPPTSTYDQAPQHPPSNYVSSDSHSI---- 437
Cdd:PHA03307  174 LPLSSPEETARAPS----SPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSgcgw 249

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   438 ---NTYPqdDYSPPSQELPLNP----HHKFPSFDFPKSSYEVPIYDPVPFEASNRDEQESYPPILASSPDLNEITSDAHA 510
Cdd:PHA03307  250 gpeNECP--LPRPAPITLPTRIweasGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSS 327

                         330
                  ....*....|....*
gi 24657342   511 AGSSKRRKRKRKPSP 525
Cdd:PHA03307  328 STSSSSESSRGAAVS 342
PTZ00395 PTZ00395
Sec24-related protein; Provisional
 259-419 2.36e-03

Sec24-related protein; Provisional


Pssm-ID: 185594 [Multi-domain]  Cd Length: 1560  Bit Score: 41.60  E-value: 2.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   259 AYSPPAFeiSTSYQSNHQQSYVP-PHPPSSHDGFAEPPSNN--YVKPPPQHPPtnsYAPPQHPSSSYDQPPqHPSSSYDQ 335
Cdd:PTZ00395  393 AYSNAAQ--SNAAQSNAGFSNAGySNPGNSNPGYNNAPNSNtpYNNPPNSNTP---YSNPPNSNPPYSNLP-YSNTPYSN 466

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   336 PPQHPPPsysqppqhPSSSYDQPAQHPSSSYDQPPKHPSSSyeQPPQHPSSSYDQPPQHpSSSYDQPPEEHP---SSYQH 412
Cdd:PTZ00395  467 APLSNAP--------PSSAKDHHSAYHAAYQHRAANQPAAN--LPTANQPAANNFHGAA-GNSVGNPFASRPfgsAPYGG 535


                  ....*..
gi 24657342   413 PPTSTYD 419
Cdd:PTZ00395  536 NAATTAD 542
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 275-453 2.39e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.51  E-value: 2.39e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342  275 HQQSYVPPHPPSSHDGFAEPPSNNYVKPPPQHPPTNSYAPPQHPSSSYDQPPQHPS-SSYDQPPQHPPPSYSQPPQHPSS 353
Cdd:PRK07764 582 WQVEAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAeASAAPAPGVAAPEHHPKHVAVPD 661

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342  354 SYDQPAQHPSSSYDQPPKHPSSSYEQPPQHPSSSYDQPPQHPSSSYDQPPEEHPSSYQHPPTSTYDQAPQhPPSNYVSSD 433
Cdd:PRK07764 662 ASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAP-SPAADDPVP 740

                        170       180
                 ....*....|....*....|
gi 24657342  434 SHSINTYPQDDYSPPSQELP 453
Cdd:PRK07764 741 LPPEPDDPPDPAGAPAQPPP 760
PHA03378 PHA03378
EBNA-3B; Provisional
 242-427 3.29e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 40.82  E-value: 3.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342  242 PKHPPKHGSI--NNPNFEIAYSPPAFEIsTSYQSNHQQSYVPPHPPSshdgfaepPSNNYVKPPPQHPPTNSYAPPQHPS 319
Cdd:PHA03378 632 PMRPLRMQPItfNVLVFPTPHQPPQVEI-TPYKPTWTQIGHIPYQPS--------PTGANTMLPIQWAPGTMQPPPRAPT 702

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342  320 SSydQPPQHPSSSYdQPPQHPPPSYSQPPQHPSSSyDQPAQHPSSSydqPPKHPSSSYEQPPQHPSSSYDQPPQHPSSSY 399
Cdd:PHA03378 703 PM--RPPAAPPGRA-QRPAAATGRARPPAAAPGRA-RPPAAAPGRA---RPPAAAPGRARPPAAAPGRARPPAAAPGAPT 775

                        170       180       190
                 ....*....|....*....|....*....|
gi 24657342  400 DQPPEEHPSSYQHPPTS--TYDQAPQHPPS 427
Cdd:PHA03378 776 PQPPPQAPPAPQQRPRGapTPQPPPQAGPT 805
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 275-409 4.11e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 40.84  E-value: 4.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   275 HQQSYVPPHPPSSHDGFAEPPSNNYVKPPPQHPPTNSYAPPQHPSSsydqppqhPSSSYDQPPQhpppsysqpPQHPSSS 354
Cdd:PRK10263  741 HEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVA--------PQPQYQQPQQ---------PVAPQPQ 803

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24657342   355 YDQPAQ--HPSSSYDQP--PKHPSSSYEQPPQHPSSSYDQPPQHP--SSSYDQPPEEHPSS 409
Cdd:PRK10263  804 YQQPQQpvAPQPQYQQPqqPVAPQPQYQQPQQPVAPQPQDTLLHPllMRNGDSRPLHKPTT 864
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 202-453 7.79e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 39.77  E-value: 7.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   202 PDAPAPVPSYPHQDLPAPDSYSIYEQKIPNVGYHQNFAEPPKHPPKHGSINNPNFEIAYSPPAFEISTSYQSNHQQSYVP 281
Cdd:PHA03307  111 PSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPP 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   282 PHPPSSHDGFAEPPSnnyvkPPPQHPPTNSYAPPQHPSSSYDQPPQHPSSSYDQPPQHPPPSYSQPPQHPSSSYDQPAQH 361
Cdd:PHA03307  191 AEPPPSTPPAAASPR-----PPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITL 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342   362 PSSSYDQPPKHPSSSyeqPPQHPSSSYDQPPQHPSSSydqPPEEHPSSYQHPPTSTYDQAPQHPPSNYVSSDSHSINTYP 441
Cdd:PHA03307  266 PTRIWEASGWNGPSS---RPGPASSSSSPRERSPSPS---PSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGA 339

                         250
                  ....*....|..
gi 24657342   442 QDDYSPPSQELP 453
Cdd:PHA03307  340 AVSPGPSPSRSP 351
COG5028 COG5028
Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking ...
 234-376 8.72e-03

Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion];


Pssm-ID: 227361 [Multi-domain]  Cd Length: 861  Bit Score: 39.39  E-value: 8.72e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342 234 YHQNFAEPPKHPPKHGSINNPNFEIAYSPPAFEISTSYQSNHQQsyvPPHPPSSHDGFAEPPSNNYVKP-PPQHPPTNSY 312
Cdd:COG5028  16 VHTGAASSKKSARPHRAYANFSAGQMGMPPYTTPPLQQQSRRQI---DQAATAMHNTGANNPAPSVMSPaFQSQQKFSSP 92

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24657342 313 APPQHPSSSYDQP--PQHPSSSY-DQPPQHPPPSYSQPPQHPSSSYDqpaQHPSSSYDQPPKHPSSS 376
Cdd:COG5028  93 YGGSMADGTAPKPtnPLVPVDLFeDQPPPISDLFLPPPPIVPPLTTN---FVGSEQSNCSPKYVRST 156
PLN02328 PLN02328
lysine-specific histone demethylase 1 homolog
 310-403 9.67e-03

lysine-specific histone demethylase 1 homolog


Pssm-ID: 215187 [Multi-domain]  Cd Length: 808  Bit Score: 39.59  E-value: 9.67e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24657342  310 NSYAPPQHPSSSYDQPPQHPSSSYDQPPQHPPPSYSQPPQHPSSSYDQpaQHPSSSYDQPPKHPSSSYEQP---PQHPSS 386
Cdd:PLN02328   3 TETKEPEDPADNVNDVVSEASSPETDLSLSPSQSEQNIENDGQNSPET--QSPLTELQPSPLPPNTTLDAPvsdSQGDES 80

                         90
                 ....*....|....*..
gi 24657342  387 SYDQPPQHPSSSYDQPP 403
Cdd:PLN02328  81 SSEQQPQNPNSTEPAPP 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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