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Conserved domains on  [gi|386770748|ref|NP_648151|]
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uncharacterized protein Dmel_CG8492 [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LYZ_C_invert cd16899
C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive ...
 596-723 1.41e-62

C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive lysozymes 1 and 2 from Musca domestica, which aid in the use of bacteria as a food source. These lysozymes have high expression in the gut and optimal lytic activity at a lower pH. Other lysozymes in this subfamily have immunological roles. e.g. Anopheles gambiae has eight lysozymes, most of which seem to have immunological roles, those some may function as digestive enzymes in larvae. C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase) has bacteriolytic properties through the hydolysis of beta-1,4, glyocosidic linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan, as well as between N-acetyl-D-glucosamine residues in chitodextrins.


:

Pssm-ID: 381618 [Multi-domain]  Cd Length: 121  Bit Score: 208.62  E-value: 1.41e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  596 KIYNRCELAKELyHRHKFPMREIPTWVCIAEHESSFNTAAVGKLNADGSEDHGLFQISDIYWCTHDQTSGKACHIECDRL 675
Cdd:cd16899     1 KIFTRCELAREL-RKLGVPRSQLANWVCLAEHESSFNTTAVGGPNSDGSGDYGLFQINDKYWCSPGGGSGNGCNVKCEDL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 386770748  676 LDSDISDDVQCIRTIHEEHtrlsgdGFNAWTVYNGHCRNQNLAKLSDC 723
Cdd:cd16899    80 LDDDISDDVKCAKKIYKEQ------GFNAWVGWKNKCKGKNLPSYSDC 121
LYZ_C_invert cd16899
C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive ...
 439-566 1.10e-61

C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive lysozymes 1 and 2 from Musca domestica, which aid in the use of bacteria as a food source. These lysozymes have high expression in the gut and optimal lytic activity at a lower pH. Other lysozymes in this subfamily have immunological roles. e.g. Anopheles gambiae has eight lysozymes, most of which seem to have immunological roles, those some may function as digestive enzymes in larvae. C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase) has bacteriolytic properties through the hydolysis of beta-1,4, glyocosidic linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan, as well as between N-acetyl-D-glucosamine residues in chitodextrins.


:

Pssm-ID: 381618 [Multi-domain]  Cd Length: 121  Bit Score: 205.92  E-value: 1.10e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  439 KVYNRCELAQELYfSHKFPMQDLATWVCIAEHESSFNTTAVGRLNADGSADHGLFQISDLYWCTHNDGGGKGCHIDCNRL 518
Cdd:cd16899     1 KIFTRCELARELR-KLGVPRSQLANWVCLAEHESSFNTTAVGGPNSDGSGDYGLFQINDKYWCSPGGGSGNGCNVKCEDL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 386770748  519 LDSDITDDVKCVRTIHEEHtrisgdGFTAWTVYNGHCRQKTRADVANC 566
Cdd:cd16899    80 LDDDISDDVKCAKKIYKEQ------GFNAWVGWKNKCKGKNLPSYSDC 121
LYZ_C_invert cd16899
C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive ...
 185-301 1.68e-54

C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive lysozymes 1 and 2 from Musca domestica, which aid in the use of bacteria as a food source. These lysozymes have high expression in the gut and optimal lytic activity at a lower pH. Other lysozymes in this subfamily have immunological roles. e.g. Anopheles gambiae has eight lysozymes, most of which seem to have immunological roles, those some may function as digestive enzymes in larvae. C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase) has bacteriolytic properties through the hydolysis of beta-1,4, glyocosidic linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan, as well as between N-acetyl-D-glucosamine residues in chitodextrins.


:

Pssm-ID: 381618 [Multi-domain]  Cd Length: 121  Bit Score: 185.51  E-value: 1.68e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  185 KIYSRCELAQELYYQHkLPMPQIPTWVCIAQHESSFNTAAVGRLNADGSADHGLFQISDLFWCTHEQRAGKGCHATCNQF 264
Cdd:cd16899     1 KIFTRCELARELRKLG-VPRSQLANWVCLAEHESSFNTTAVGGPNSDGSGDYGLFQINDKYWCSPGGGSGNGCNVKCEDL 79

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 386770748  265 LDSSIGDDVQCIRRIHQEHtqisgdGFNAWTVYKRNC 301
Cdd:cd16899    80 LDDDISDDVKCAKKIYKEQ------GFNAWVGWKNKC 110
LYZ_C_invert cd16899
C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive ...
 18-144 1.29e-44

C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive lysozymes 1 and 2 from Musca domestica, which aid in the use of bacteria as a food source. These lysozymes have high expression in the gut and optimal lytic activity at a lower pH. Other lysozymes in this subfamily have immunological roles. e.g. Anopheles gambiae has eight lysozymes, most of which seem to have immunological roles, those some may function as digestive enzymes in larvae. C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase) has bacteriolytic properties through the hydolysis of beta-1,4, glyocosidic linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan, as well as between N-acetyl-D-glucosamine residues in chitodextrins.


:

Pssm-ID: 381618 [Multi-domain]  Cd Length: 121  Bit Score: 157.39  E-value: 1.29e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   18 KIFDRCELANLLqHRFGLPAAQVATLVCIAQHSSDFNTAAFGGGVGLGGGSHGLFQISDVYWCSPP-GQGKGCGLSCSRL 96
Cdd:cd16899     1 KIFTRCELAREL-RKLGVPRSQLANWVCLAEHESSFNTTAVGGPNSDGSGDYGLFQINDKYWCSPGgGSGNGCNVKCEDL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 386770748   97 RDDDIADDVLCVRKIYAEHqrisgdGFTAWQAYDAYCRQDANSYVAGC 144
Cdd:cd16899    80 LDDDISDDVKCAKKIYKEQ------GFNAWVGWKNKCKGKNLPSYSDC 121
PHA03255 super family cl31530
BDLF3; Provisional
 937-1067 3.45e-04

BDLF3; Provisional


The actual alignment was detected with superfamily member PHA03255:

Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 43.74  E-value: 3.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  937 SVTTTTRKPQTASTTKPVSTTAKTTSLPLWSW--------QTSTTAKPTISESGNRYTTSTTRSVITNKPNthPTIAAVS 1008
Cdd:PHA03255   21 SLIWTSSGSSTASAGNVTGTTAVTTPSPSASGpstnqsttLTTTSAPITTTAILSTNTTTVTSTGTTVTPV--PTTSNAS 98

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 386770748 1009 RPTTraTTRSTNGPIRTTSQpGTYLNTPLSSrspirQSTIRSStvfttrSTTRPTIRST 1067
Cdd:PHA03255   99 TINV--TTKVTAQNITATEA-GTGTSTGVTS-----NVTTRSS------STTSATTRIT 143
Herpes_BLLF1 super family cl37540
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 823-1261 2.14e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


The actual alignment was detected with superfamily member pfam05109:

Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 42.60  E-value: 2.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   823 GAPVYSTKKPNYDHNPF-LKAPGSVTPSVKPSHASQEVKLHDSTSyaqnpflsllGKPIVPAQAPIK--PQSKPPSPSKS 899
Cdd:pfam05109  440 AAPNTTTGLPSSTHVPTnLTAPASTGPTVSTADVTSPTPAGTTSG----------ASPVTPSPSPRDngTESKAPDMTSP 509

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   900 TQLVSRPYVSSDSfrnevikftatsaavattasfTKQSVTTTTRKPQTASTTKPVSTTAKTTSLPLWSWQTSTTAKPTIS 979
Cdd:pfam05109  510 TSAVTTPTPNATS---------------------PTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPN 568

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   980 ES-GNRYTTSTTRSVITNKPN-THPTIAAVSrPTTRATTRSTNGpirTTSQPgTYLNTPLSSRSPIR--QSTIRSSTvfT 1055
Cdd:pfam05109  569 ATiPTLGKTSPTSAVTTPTPNaTSPTVGETS-PQANTTNHTLGG---TSSTP-VVTSPPKNATSAVTtgQHNITSSS--T 641

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  1056 TRSTTRPTirSTTHAISRPTSSPTTRPTTRLTTRPTTRTTTRASVSPTTRPTVGLTTYQPTRTPTSITRRPIYTTQKQYT 1135
Cdd:pfam05109  642 SSMSLRPS--SISETLSPSTSDNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTSQASGPGNSSTST 719

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  1136 TTTRATTPYPTVSKPTTRPSTTTRPLTTtryIPTtrqsvITQTTNRNSAIYLPRNNTISTNRSTTKSPYHYvsinkpttr 1215
Cdd:pfam05109  720 KPGEVNVTKGTPPKNATSPQAPSGQKTA---VPT-----VTSTGGKANSTTGGKHTTGHGARTSTEPTTDY--------- 782

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*...
gi 386770748  1216 stTSTRPSTTIRYSPTTRQPPTTRST--TRYSAITAFSTRQTSTTPRP 1261
Cdd:pfam05109  783 --GGDSTTPRTRYNATTYLPPSTSSKlrPRWTFTSPPVTTAQATVPVP 828
 
Name Accession Description Interval E-value
LYZ_C_invert cd16899
C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive ...
 596-723 1.41e-62

C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive lysozymes 1 and 2 from Musca domestica, which aid in the use of bacteria as a food source. These lysozymes have high expression in the gut and optimal lytic activity at a lower pH. Other lysozymes in this subfamily have immunological roles. e.g. Anopheles gambiae has eight lysozymes, most of which seem to have immunological roles, those some may function as digestive enzymes in larvae. C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase) has bacteriolytic properties through the hydolysis of beta-1,4, glyocosidic linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan, as well as between N-acetyl-D-glucosamine residues in chitodextrins.


Pssm-ID: 381618 [Multi-domain]  Cd Length: 121  Bit Score: 208.62  E-value: 1.41e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  596 KIYNRCELAKELyHRHKFPMREIPTWVCIAEHESSFNTAAVGKLNADGSEDHGLFQISDIYWCTHDQTSGKACHIECDRL 675
Cdd:cd16899     1 KIFTRCELAREL-RKLGVPRSQLANWVCLAEHESSFNTTAVGGPNSDGSGDYGLFQINDKYWCSPGGGSGNGCNVKCEDL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 386770748  676 LDSDISDDVQCIRTIHEEHtrlsgdGFNAWTVYNGHCRNQNLAKLSDC 723
Cdd:cd16899    80 LDDDISDDVKCAKKIYKEQ------GFNAWVGWKNKCKGKNLPSYSDC 121
LYZ_C_invert cd16899
C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive ...
 439-566 1.10e-61

C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive lysozymes 1 and 2 from Musca domestica, which aid in the use of bacteria as a food source. These lysozymes have high expression in the gut and optimal lytic activity at a lower pH. Other lysozymes in this subfamily have immunological roles. e.g. Anopheles gambiae has eight lysozymes, most of which seem to have immunological roles, those some may function as digestive enzymes in larvae. C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase) has bacteriolytic properties through the hydolysis of beta-1,4, glyocosidic linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan, as well as between N-acetyl-D-glucosamine residues in chitodextrins.


Pssm-ID: 381618 [Multi-domain]  Cd Length: 121  Bit Score: 205.92  E-value: 1.10e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  439 KVYNRCELAQELYfSHKFPMQDLATWVCIAEHESSFNTTAVGRLNADGSADHGLFQISDLYWCTHNDGGGKGCHIDCNRL 518
Cdd:cd16899     1 KIFTRCELARELR-KLGVPRSQLANWVCLAEHESSFNTTAVGGPNSDGSGDYGLFQINDKYWCSPGGGSGNGCNVKCEDL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 386770748  519 LDSDITDDVKCVRTIHEEHtrisgdGFTAWTVYNGHCRQKTRADVANC 566
Cdd:cd16899    80 LDDDISDDVKCAKKIYKEQ------GFNAWVGWKNKCKGKNLPSYSDC 121
LYZ_C_invert cd16899
C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive ...
 185-301 1.68e-54

C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive lysozymes 1 and 2 from Musca domestica, which aid in the use of bacteria as a food source. These lysozymes have high expression in the gut and optimal lytic activity at a lower pH. Other lysozymes in this subfamily have immunological roles. e.g. Anopheles gambiae has eight lysozymes, most of which seem to have immunological roles, those some may function as digestive enzymes in larvae. C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase) has bacteriolytic properties through the hydolysis of beta-1,4, glyocosidic linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan, as well as between N-acetyl-D-glucosamine residues in chitodextrins.


Pssm-ID: 381618 [Multi-domain]  Cd Length: 121  Bit Score: 185.51  E-value: 1.68e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  185 KIYSRCELAQELYYQHkLPMPQIPTWVCIAQHESSFNTAAVGRLNADGSADHGLFQISDLFWCTHEQRAGKGCHATCNQF 264
Cdd:cd16899     1 KIFTRCELARELRKLG-VPRSQLANWVCLAEHESSFNTTAVGGPNSDGSGDYGLFQINDKYWCSPGGGSGNGCNVKCEDL 79

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 386770748  265 LDSSIGDDVQCIRRIHQEHtqisgdGFNAWTVYKRNC 301
Cdd:cd16899    80 LDDDISDDVKCAKKIYKEQ------GFNAWVGWKNKC 110
LYZ_C_invert cd16899
C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive ...
 18-144 1.29e-44

C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive lysozymes 1 and 2 from Musca domestica, which aid in the use of bacteria as a food source. These lysozymes have high expression in the gut and optimal lytic activity at a lower pH. Other lysozymes in this subfamily have immunological roles. e.g. Anopheles gambiae has eight lysozymes, most of which seem to have immunological roles, those some may function as digestive enzymes in larvae. C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase) has bacteriolytic properties through the hydolysis of beta-1,4, glyocosidic linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan, as well as between N-acetyl-D-glucosamine residues in chitodextrins.


Pssm-ID: 381618 [Multi-domain]  Cd Length: 121  Bit Score: 157.39  E-value: 1.29e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   18 KIFDRCELANLLqHRFGLPAAQVATLVCIAQHSSDFNTAAFGGGVGLGGGSHGLFQISDVYWCSPP-GQGKGCGLSCSRL 96
Cdd:cd16899     1 KIFTRCELAREL-RKLGVPRSQLANWVCLAEHESSFNTTAVGGPNSDGSGDYGLFQINDKYWCSPGgGSGNGCNVKCEDL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 386770748   97 RDDDIADDVLCVRKIYAEHqrisgdGFTAWQAYDAYCRQDANSYVAGC 144
Cdd:cd16899    80 LDDDISDDVKCAKKIYKEQ------GFNAWVGWKNKCKGKNLPSYSDC 121
LYZ1 smart00263
Alpha-lactalbumin / lysozyme C;
596-724 1.83e-38

Alpha-lactalbumin / lysozyme C;


Pssm-ID: 197612  Cd Length: 127  Bit Score: 139.73  E-value: 1.83e-38
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748    596 KIYNRCELAKELYHRHKFPMREI--PTWVCIAEHESSFNTAAVGKlNADGSEDHGLFQISDIYWCTHDQT--SGKACHIE 671
Cdd:smart00263    1 KVFTRCELARELKRLGLDGYRGIslANWVCLAFHESGYNTQATNY-NNGGSTDYGIFQINSKYWCNDGKTpgSVNACGIS 79

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|....
gi 386770748    672 CDRLLDSDISDDVQCIRTIHEEHtrlsgdGFNAWTVYNGHCRNQNLAK-LSDCF 724
Cdd:smart00263   80 CSKLLDDDITDDVKCAKKIVSDQ------GIDAWVAWKNHCQGEDLSQwIRGCG 127
LYZ1 smart00263
Alpha-lactalbumin / lysozyme C;
439-567 2.78e-38

Alpha-lactalbumin / lysozyme C;


Pssm-ID: 197612  Cd Length: 127  Bit Score: 139.35  E-value: 2.78e-38
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748    439 KVYNRCELAQELYFSHK--FPMQDLATWVCIAEHESSFNTTAVGRlNADGSADHGLFQISDLYWCthNDG----GGKGCH 512
Cdd:smart00263    1 KVFTRCELARELKRLGLdgYRGISLANWVCLAFHESGYNTQATNY-NNGGSTDYGIFQINSKYWC--NDGktpgSVNACG 77

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 386770748    513 IDCNRLLDSDITDDVKCVRTIHEEHtrisgdGFTAWTVYNGHCR-QKTRADVANCF 567
Cdd:smart00263   78 ISCSKLLDDDITDDVKCAKKIVSDQ------GIDAWVAWKNHCQgEDLSQWIRGCG 127
LYZ1 smart00263
Alpha-lactalbumin / lysozyme C;
185-313 3.37e-35

Alpha-lactalbumin / lysozyme C;


Pssm-ID: 197612  Cd Length: 127  Bit Score: 130.49  E-value: 3.37e-35
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748    185 KIYSRCELAQELyyqHKLPMP-----QIPTWVCIAQHESSFNTAAVGRlNADGSADHGLFQISDLFWCTHEQ--RAGKGC 257
Cdd:smart00263    1 KVFTRCELAREL---KRLGLDgyrgiSLANWVCLAFHESGYNTQATNY-NNGGSTDYGIFQINSKYWCNDGKtpGSVNAC 76

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 386770748    258 HATCNQFLDSSIGDDVQCIRRIHQEHtqisgdGFNAWTVYKRNCLNQHYEQ-IAACF 313
Cdd:smart00263   77 GISCSKLLDDDITDDVKCAKKIVSDQ------GIDAWVAWKNHCQGEDLSQwIRGCG 127
Lys pfam00062
C-type lysozyme/alpha-lactalbumin family; Alpha-lactalbumin is the regulatory subunit of ...
 439-558 2.62e-31

C-type lysozyme/alpha-lactalbumin family; Alpha-lactalbumin is the regulatory subunit of lactose synthase, changing the substrate specificity of galactosyltransferase from N-acetylglucosamine to glucose. C-type lysozymes are secreted bacteriolytic enzymes that cleave the peptidoglycan of bacterial cell walls. Structure is a multi-domain, mixed alpha and beta fold, containing four conserved disulfide bonds.


Pssm-ID: 395016  Cd Length: 123  Bit Score: 119.45  E-value: 2.62e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   439 KVYNRCELAQELyfsHKFPMQD-----LATWVCIAEHESSFNTTAVGrlNADGSADHGLFQISDLYWCthNDGGGK---- 509
Cdd:pfam00062    1 KQFTRCELAREL---KKLGMDGyrgisLAEWVCLAFHESGYDTQAIV--YNNGSTDYGIFQINDKYWC--KDGKTPqsvn 73

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 386770748   510 GCHIDCNRLLDSDITDDVKCVRTIheehtrISGDGFTAWTVYNGHCRQK 558
Cdd:pfam00062   74 ICGISCDKLLDDDITDDIMCAKKI------LDPQGIDAWLAWKPHCSED 116
Lys pfam00062
C-type lysozyme/alpha-lactalbumin family; Alpha-lactalbumin is the regulatory subunit of ...
 596-723 5.48e-31

C-type lysozyme/alpha-lactalbumin family; Alpha-lactalbumin is the regulatory subunit of lactose synthase, changing the substrate specificity of galactosyltransferase from N-acetylglucosamine to glucose. C-type lysozymes are secreted bacteriolytic enzymes that cleave the peptidoglycan of bacterial cell walls. Structure is a multi-domain, mixed alpha and beta fold, containing four conserved disulfide bonds.


Pssm-ID: 395016  Cd Length: 123  Bit Score: 118.29  E-value: 5.48e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   596 KIYNRCELAKELYHRHKFPMREI--PTWVCIAEHESSFNTAAVGKLNadGSEDHGLFQISDIYWCTHDQT--SGKACHIE 671
Cdd:pfam00062    1 KQFTRCELARELKKLGMDGYRGIslAEWVCLAFHESGYDTQAIVYNN--GSTDYGIFQINDKYWCKDGKTpqSVNICGIS 78

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 386770748   672 CDRLLDSDISDDVQCIRTIheehtrLSGDGFNAWTVYNGHCRnQNLAKLSDC 723
Cdd:pfam00062   79 CDKLLDDDITDDIMCAKKI------LDPQGIDAWLAWKPHCS-EDLEQWIGC 123
LYZ1 smart00263
Alpha-lactalbumin / lysozyme C;
18-145 8.73e-31

Alpha-lactalbumin / lysozyme C;


Pssm-ID: 197612  Cd Length: 127  Bit Score: 118.16  E-value: 8.73e-31
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748     18 KIFDRCELANLL--QHRFGLPAAQVATLVCIAQHSSDFNTAAFGGGVGLGGGSHgLFQISDVYWCSP---PGQGKGCGLS 92
Cdd:smart00263    1 KVFTRCELARELkrLGLDGYRGISLANWVCLAFHESGYNTQATNYNNGGSTDYG-IFQINSKYWCNDgktPGSVNACGIS 79

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|....
gi 386770748     93 CSRLRDDDIADDVLCVRKIYAEHqrisgdGFTAWQAYDAYCR-QDANSYVAGCG 145
Cdd:smart00263   80 CSKLLDDDITDDVKCAKKIVSDQ------GIDAWVAWKNHCQgEDLSQWIRGCG 127
Lys pfam00062
C-type lysozyme/alpha-lactalbumin family; Alpha-lactalbumin is the regulatory subunit of ...
 185-312 3.44e-28

C-type lysozyme/alpha-lactalbumin family; Alpha-lactalbumin is the regulatory subunit of lactose synthase, changing the substrate specificity of galactosyltransferase from N-acetylglucosamine to glucose. C-type lysozymes are secreted bacteriolytic enzymes that cleave the peptidoglycan of bacterial cell walls. Structure is a multi-domain, mixed alpha and beta fold, containing four conserved disulfide bonds.


Pssm-ID: 395016  Cd Length: 123  Bit Score: 110.59  E-value: 3.44e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   185 KIYSRCELAQELyyqHKLPMP-----QIPTWVCIAQHESSFNTAAVGrlNADGSADHGLFQISDLFWCTHEQ--RAGKGC 257
Cdd:pfam00062    1 KQFTRCELAREL---KKLGMDgyrgiSLAEWVCLAFHESGYDTQAIV--YNNGSTDYGIFQINDKYWCKDGKtpQSVNIC 75

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 386770748   258 HATCNQFLDSSIGDDVQCIRRIhqehtqISGDGFNAWTVYKRNClNQHYEQIAAC 312
Cdd:pfam00062   76 GISCDKLLDDDITDDIMCAKKI------LDPQGIDAWLAWKPHC-SEDLEQWIGC 123
Lys pfam00062
C-type lysozyme/alpha-lactalbumin family; Alpha-lactalbumin is the regulatory subunit of ...
 18-144 7.01e-26

C-type lysozyme/alpha-lactalbumin family; Alpha-lactalbumin is the regulatory subunit of lactose synthase, changing the substrate specificity of galactosyltransferase from N-acetylglucosamine to glucose. C-type lysozymes are secreted bacteriolytic enzymes that cleave the peptidoglycan of bacterial cell walls. Structure is a multi-domain, mixed alpha and beta fold, containing four conserved disulfide bonds.


Pssm-ID: 395016  Cd Length: 123  Bit Score: 103.65  E-value: 7.01e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748    18 KIFDRCELANLLQhRFGLPA---AQVATLVCIAQHSSDFNTAAFGGGVGLGGGShgLFQISDVYWCSP---PGQGKGCGL 91
Cdd:pfam00062    1 KQFTRCELARELK-KLGMDGyrgISLAEWVCLAFHESGYDTQAIVYNNGSTDYG--IFQINDKYWCKDgktPQSVNICGI 77

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 386770748    92 SCSRLRDDDIADDVLCVRKIyaehqrISGDGFTAWQAYDAYCRQDANSYVaGC 144
Cdd:pfam00062   78 SCDKLLDDDITDDIMCAKKI------LDPQGIDAWLAWKPHCSEDLEQWI-GC 123
PHA03255 PHA03255
BDLF3; Provisional
 937-1067 3.45e-04

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 43.74  E-value: 3.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  937 SVTTTTRKPQTASTTKPVSTTAKTTSLPLWSW--------QTSTTAKPTISESGNRYTTSTTRSVITNKPNthPTIAAVS 1008
Cdd:PHA03255   21 SLIWTSSGSSTASAGNVTGTTAVTTPSPSASGpstnqsttLTTTSAPITTTAILSTNTTTVTSTGTTVTPV--PTTSNAS 98

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 386770748 1009 RPTTraTTRSTNGPIRTTSQpGTYLNTPLSSrspirQSTIRSStvfttrSTTRPTIRST 1067
Cdd:PHA03255   99 TINV--TTKVTAQNITATEA-GTGTSTGVTS-----NVTTRSS------STTSATTRIT 143
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
935-1068 7.29e-04

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 43.50  E-value: 7.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   935 KQSVTTTTRKPQ-TASTTKPVSTTAKTTSLPLWSWQTSTTAKPTISESGNRYTTSTTRSVI-----TNKPNTH-PTIAAV 1007
Cdd:pfam05539  169 KTAVTTSKTTSWpTEVSHPTYPSQVTPQSQPATQGHQTATANQRLSSTEPVGTQGTTTSSNpepqtEPPPSQRgPSGSPQ 248

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 386770748  1008 SRPTTRATTRSTNGPIRTTSQPGTYLNTPLSSRSPIRQSTIRSSTvfTTRSTTRPTIRSTT 1068
Cdd:pfam05539  249 HPPSTTSQDQSTTGDGQEHTQRRKTPPATSNRRSPHSTATPPPTT--KRQETGRPTPRPTA 307
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 823-1261 2.14e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 42.60  E-value: 2.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   823 GAPVYSTKKPNYDHNPF-LKAPGSVTPSVKPSHASQEVKLHDSTSyaqnpflsllGKPIVPAQAPIK--PQSKPPSPSKS 899
Cdd:pfam05109  440 AAPNTTTGLPSSTHVPTnLTAPASTGPTVSTADVTSPTPAGTTSG----------ASPVTPSPSPRDngTESKAPDMTSP 509

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   900 TQLVSRPYVSSDSfrnevikftatsaavattasfTKQSVTTTTRKPQTASTTKPVSTTAKTTSLPLWSWQTSTTAKPTIS 979
Cdd:pfam05109  510 TSAVTTPTPNATS---------------------PTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPN 568

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   980 ES-GNRYTTSTTRSVITNKPN-THPTIAAVSrPTTRATTRSTNGpirTTSQPgTYLNTPLSSRSPIR--QSTIRSSTvfT 1055
Cdd:pfam05109  569 ATiPTLGKTSPTSAVTTPTPNaTSPTVGETS-PQANTTNHTLGG---TSSTP-VVTSPPKNATSAVTtgQHNITSSS--T 641

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  1056 TRSTTRPTirSTTHAISRPTSSPTTRPTTRLTTRPTTRTTTRASVSPTTRPTVGLTTYQPTRTPTSITRRPIYTTQKQYT 1135
Cdd:pfam05109  642 SSMSLRPS--SISETLSPSTSDNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTSQASGPGNSSTST 719

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  1136 TTTRATTPYPTVSKPTTRPSTTTRPLTTtryIPTtrqsvITQTTNRNSAIYLPRNNTISTNRSTTKSPYHYvsinkpttr 1215
Cdd:pfam05109  720 KPGEVNVTKGTPPKNATSPQAPSGQKTA---VPT-----VTSTGGKANSTTGGKHTTGHGARTSTEPTTDY--------- 782

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*...
gi 386770748  1216 stTSTRPSTTIRYSPTTRQPPTTRST--TRYSAITAFSTRQTSTTPRP 1261
Cdd:pfam05109  783 --GGDSTTPRTRYNATTYLPPSTSSKlrPRWTFTSPPVTTAQATVPVP 828
 
Name Accession Description Interval E-value
LYZ_C_invert cd16899
C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive ...
 596-723 1.41e-62

C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive lysozymes 1 and 2 from Musca domestica, which aid in the use of bacteria as a food source. These lysozymes have high expression in the gut and optimal lytic activity at a lower pH. Other lysozymes in this subfamily have immunological roles. e.g. Anopheles gambiae has eight lysozymes, most of which seem to have immunological roles, those some may function as digestive enzymes in larvae. C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase) has bacteriolytic properties through the hydolysis of beta-1,4, glyocosidic linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan, as well as between N-acetyl-D-glucosamine residues in chitodextrins.


Pssm-ID: 381618 [Multi-domain]  Cd Length: 121  Bit Score: 208.62  E-value: 1.41e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  596 KIYNRCELAKELyHRHKFPMREIPTWVCIAEHESSFNTAAVGKLNADGSEDHGLFQISDIYWCTHDQTSGKACHIECDRL 675
Cdd:cd16899     1 KIFTRCELAREL-RKLGVPRSQLANWVCLAEHESSFNTTAVGGPNSDGSGDYGLFQINDKYWCSPGGGSGNGCNVKCEDL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 386770748  676 LDSDISDDVQCIRTIHEEHtrlsgdGFNAWTVYNGHCRNQNLAKLSDC 723
Cdd:cd16899    80 LDDDISDDVKCAKKIYKEQ------GFNAWVGWKNKCKGKNLPSYSDC 121
LYZ_C_invert cd16899
C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive ...
 439-566 1.10e-61

C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive lysozymes 1 and 2 from Musca domestica, which aid in the use of bacteria as a food source. These lysozymes have high expression in the gut and optimal lytic activity at a lower pH. Other lysozymes in this subfamily have immunological roles. e.g. Anopheles gambiae has eight lysozymes, most of which seem to have immunological roles, those some may function as digestive enzymes in larvae. C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase) has bacteriolytic properties through the hydolysis of beta-1,4, glyocosidic linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan, as well as between N-acetyl-D-glucosamine residues in chitodextrins.


Pssm-ID: 381618 [Multi-domain]  Cd Length: 121  Bit Score: 205.92  E-value: 1.10e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  439 KVYNRCELAQELYfSHKFPMQDLATWVCIAEHESSFNTTAVGRLNADGSADHGLFQISDLYWCTHNDGGGKGCHIDCNRL 518
Cdd:cd16899     1 KIFTRCELARELR-KLGVPRSQLANWVCLAEHESSFNTTAVGGPNSDGSGDYGLFQINDKYWCSPGGGSGNGCNVKCEDL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 386770748  519 LDSDITDDVKCVRTIHEEHtrisgdGFTAWTVYNGHCRQKTRADVANC 566
Cdd:cd16899    80 LDDDISDDVKCAKKIYKEQ------GFNAWVGWKNKCKGKNLPSYSDC 121
LYZ_C_invert cd16899
C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive ...
 185-301 1.68e-54

C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive lysozymes 1 and 2 from Musca domestica, which aid in the use of bacteria as a food source. These lysozymes have high expression in the gut and optimal lytic activity at a lower pH. Other lysozymes in this subfamily have immunological roles. e.g. Anopheles gambiae has eight lysozymes, most of which seem to have immunological roles, those some may function as digestive enzymes in larvae. C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase) has bacteriolytic properties through the hydolysis of beta-1,4, glyocosidic linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan, as well as between N-acetyl-D-glucosamine residues in chitodextrins.


Pssm-ID: 381618 [Multi-domain]  Cd Length: 121  Bit Score: 185.51  E-value: 1.68e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  185 KIYSRCELAQELYYQHkLPMPQIPTWVCIAQHESSFNTAAVGRLNADGSADHGLFQISDLFWCTHEQRAGKGCHATCNQF 264
Cdd:cd16899     1 KIFTRCELARELRKLG-VPRSQLANWVCLAEHESSFNTTAVGGPNSDGSGDYGLFQINDKYWCSPGGGSGNGCNVKCEDL 79

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 386770748  265 LDSSIGDDVQCIRRIHQEHtqisgdGFNAWTVYKRNC 301
Cdd:cd16899    80 LDDDISDDVKCAKKIYKEQ------GFNAWVGWKNKC 110
LYZ_C_invert cd16899
C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive ...
 18-144 1.29e-44

C-type invertebrate lysozyme; C-type lysozyme proteins of invertebrates, including digestive lysozymes 1 and 2 from Musca domestica, which aid in the use of bacteria as a food source. These lysozymes have high expression in the gut and optimal lytic activity at a lower pH. Other lysozymes in this subfamily have immunological roles. e.g. Anopheles gambiae has eight lysozymes, most of which seem to have immunological roles, those some may function as digestive enzymes in larvae. C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase) has bacteriolytic properties through the hydolysis of beta-1,4, glyocosidic linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan, as well as between N-acetyl-D-glucosamine residues in chitodextrins.


Pssm-ID: 381618 [Multi-domain]  Cd Length: 121  Bit Score: 157.39  E-value: 1.29e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   18 KIFDRCELANLLqHRFGLPAAQVATLVCIAQHSSDFNTAAFGGGVGLGGGSHGLFQISDVYWCSPP-GQGKGCGLSCSRL 96
Cdd:cd16899     1 KIFTRCELAREL-RKLGVPRSQLANWVCLAEHESSFNTTAVGGPNSDGSGDYGLFQINDKYWCSPGgGSGNGCNVKCEDL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 386770748   97 RDDDIADDVLCVRKIYAEHqrisgdGFTAWQAYDAYCRQDANSYVAGC 144
Cdd:cd16899    80 LDDDISDDVKCAKKIYKEQ------GFNAWVGWKNKCKGKNLPSYSDC 121
LYZ1 smart00263
Alpha-lactalbumin / lysozyme C;
596-724 1.83e-38

Alpha-lactalbumin / lysozyme C;


Pssm-ID: 197612  Cd Length: 127  Bit Score: 139.73  E-value: 1.83e-38
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748    596 KIYNRCELAKELYHRHKFPMREI--PTWVCIAEHESSFNTAAVGKlNADGSEDHGLFQISDIYWCTHDQT--SGKACHIE 671
Cdd:smart00263    1 KVFTRCELARELKRLGLDGYRGIslANWVCLAFHESGYNTQATNY-NNGGSTDYGIFQINSKYWCNDGKTpgSVNACGIS 79

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|....
gi 386770748    672 CDRLLDSDISDDVQCIRTIHEEHtrlsgdGFNAWTVYNGHCRNQNLAK-LSDCF 724
Cdd:smart00263   80 CSKLLDDDITDDVKCAKKIVSDQ------GIDAWVAWKNHCQGEDLSQwIRGCG 127
LYZ1 smart00263
Alpha-lactalbumin / lysozyme C;
439-567 2.78e-38

Alpha-lactalbumin / lysozyme C;


Pssm-ID: 197612  Cd Length: 127  Bit Score: 139.35  E-value: 2.78e-38
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748    439 KVYNRCELAQELYFSHK--FPMQDLATWVCIAEHESSFNTTAVGRlNADGSADHGLFQISDLYWCthNDG----GGKGCH 512
Cdd:smart00263    1 KVFTRCELARELKRLGLdgYRGISLANWVCLAFHESGYNTQATNY-NNGGSTDYGIFQINSKYWC--NDGktpgSVNACG 77

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 386770748    513 IDCNRLLDSDITDDVKCVRTIHEEHtrisgdGFTAWTVYNGHCR-QKTRADVANCF 567
Cdd:smart00263   78 ISCSKLLDDDITDDVKCAKKIVSDQ------GIDAWVAWKNHCQgEDLSQWIRGCG 127
LYZ1 smart00263
Alpha-lactalbumin / lysozyme C;
185-313 3.37e-35

Alpha-lactalbumin / lysozyme C;


Pssm-ID: 197612  Cd Length: 127  Bit Score: 130.49  E-value: 3.37e-35
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748    185 KIYSRCELAQELyyqHKLPMP-----QIPTWVCIAQHESSFNTAAVGRlNADGSADHGLFQISDLFWCTHEQ--RAGKGC 257
Cdd:smart00263    1 KVFTRCELAREL---KRLGLDgyrgiSLANWVCLAFHESGYNTQATNY-NNGGSTDYGIFQINSKYWCNDGKtpGSVNAC 76

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 386770748    258 HATCNQFLDSSIGDDVQCIRRIHQEHtqisgdGFNAWTVYKRNCLNQHYEQ-IAACF 313
Cdd:smart00263   77 GISCSKLLDDDITDDVKCAKKIVSDQ------GIDAWVAWKNHCQGEDLSQwIRGCG 127
LYZ_C cd16897
C-type lysozyme; C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase). ...
 439-556 1.73e-33

C-type lysozyme; C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase). In humans, lysozyme is found in a wide variety of tissue types and body fluids. It has bacteriolytic properties through the hydolysis of beta-1,4, glyocosidic linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan, as well as between N-acetyl-D-glucosamine residues in chitodextrins. This family also includes digestive stomach lysozyme, which allow ruminants to digest bacteria in the foregut. The mammalian enzyme is related to lysozyme found hen egg-whites and related species.


Pssm-ID: 340383  Cd Length: 126  Bit Score: 125.84  E-value: 1.73e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  439 KVYNRCELAQELyfsHKFPMqD------LATWVCIAEHESSFNTTAVGRlNADGSADHGLFQISDLYWCthNDGGGK--- 509
Cdd:cd16897     1 KIFSRCELARIL---KRGGL-DgyrgysLANWVCLAYYESGFNTRATNE-NPDGSTDYGIFQINSRYWC--NDGKTPskn 73

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 386770748  510 GCHIDCNRLLDSDITDDVKCVRTIHEEHtrisgDGFTAWTVYNGHCR 556
Cdd:cd16897    74 LCHISCSDLLNDDITDDIKCAKKIVKDP-----QGMGAWVAWRLHCE 115
LYZ_C cd16897
C-type lysozyme; C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase). ...
 596-723 2.86e-32

C-type lysozyme; C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase). In humans, lysozyme is found in a wide variety of tissue types and body fluids. It has bacteriolytic properties through the hydolysis of beta-1,4, glyocosidic linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan, as well as between N-acetyl-D-glucosamine residues in chitodextrins. This family also includes digestive stomach lysozyme, which allow ruminants to digest bacteria in the foregut. The mammalian enzyme is related to lysozyme found hen egg-whites and related species.


Pssm-ID: 340383  Cd Length: 126  Bit Score: 121.99  E-value: 2.86e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  596 KIYNRCELAKELYHRH--KFPMREIPTWVCIAEHESSFNTAAVGKlNADGSEDHGLFQISDIYWCTHDQTSGK-ACHIEC 672
Cdd:cd16897     1 KIFSRCELARILKRGGldGYRGYSLANWVCLAYYESGFNTRATNE-NPDGSTDYGIFQINSRYWCNDGKTPSKnLCHISC 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 386770748  673 DRLLDSDISDDVQCIRTIHEEHtrlsgDGFNAWTVYNGHCRNQNLAK-LSDC 723
Cdd:cd16897    80 SDLLNDDITDDIKCAKKIVKDP-----QGMGAWVAWRLHCEGRDLSRwLDGC 126
Lys pfam00062
C-type lysozyme/alpha-lactalbumin family; Alpha-lactalbumin is the regulatory subunit of ...
 439-558 2.62e-31

C-type lysozyme/alpha-lactalbumin family; Alpha-lactalbumin is the regulatory subunit of lactose synthase, changing the substrate specificity of galactosyltransferase from N-acetylglucosamine to glucose. C-type lysozymes are secreted bacteriolytic enzymes that cleave the peptidoglycan of bacterial cell walls. Structure is a multi-domain, mixed alpha and beta fold, containing four conserved disulfide bonds.


Pssm-ID: 395016  Cd Length: 123  Bit Score: 119.45  E-value: 2.62e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   439 KVYNRCELAQELyfsHKFPMQD-----LATWVCIAEHESSFNTTAVGrlNADGSADHGLFQISDLYWCthNDGGGK---- 509
Cdd:pfam00062    1 KQFTRCELAREL---KKLGMDGyrgisLAEWVCLAFHESGYDTQAIV--YNNGSTDYGIFQINDKYWC--KDGKTPqsvn 73

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 386770748   510 GCHIDCNRLLDSDITDDVKCVRTIheehtrISGDGFTAWTVYNGHCRQK 558
Cdd:pfam00062   74 ICGISCDKLLDDDITDDIMCAKKI------LDPQGIDAWLAWKPHCSED 116
Lys pfam00062
C-type lysozyme/alpha-lactalbumin family; Alpha-lactalbumin is the regulatory subunit of ...
 596-723 5.48e-31

C-type lysozyme/alpha-lactalbumin family; Alpha-lactalbumin is the regulatory subunit of lactose synthase, changing the substrate specificity of galactosyltransferase from N-acetylglucosamine to glucose. C-type lysozymes are secreted bacteriolytic enzymes that cleave the peptidoglycan of bacterial cell walls. Structure is a multi-domain, mixed alpha and beta fold, containing four conserved disulfide bonds.


Pssm-ID: 395016  Cd Length: 123  Bit Score: 118.29  E-value: 5.48e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   596 KIYNRCELAKELYHRHKFPMREI--PTWVCIAEHESSFNTAAVGKLNadGSEDHGLFQISDIYWCTHDQT--SGKACHIE 671
Cdd:pfam00062    1 KQFTRCELARELKKLGMDGYRGIslAEWVCLAFHESGYDTQAIVYNN--GSTDYGIFQINDKYWCKDGKTpqSVNICGIS 78

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 386770748   672 CDRLLDSDISDDVQCIRTIheehtrLSGDGFNAWTVYNGHCRnQNLAKLSDC 723
Cdd:pfam00062   79 CDKLLDDDITDDIMCAKKI------LDPQGIDAWLAWKPHCS-EDLEQWIGC 123
LYZ1 smart00263
Alpha-lactalbumin / lysozyme C;
18-145 8.73e-31

Alpha-lactalbumin / lysozyme C;


Pssm-ID: 197612  Cd Length: 127  Bit Score: 118.16  E-value: 8.73e-31
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748     18 KIFDRCELANLL--QHRFGLPAAQVATLVCIAQHSSDFNTAAFGGGVGLGGGSHgLFQISDVYWCSP---PGQGKGCGLS 92
Cdd:smart00263    1 KVFTRCELARELkrLGLDGYRGISLANWVCLAFHESGYNTQATNYNNGGSTDYG-IFQINSKYWCNDgktPGSVNACGIS 79

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|....
gi 386770748     93 CSRLRDDDIADDVLCVRKIYAEHqrisgdGFTAWQAYDAYCR-QDANSYVAGCG 145
Cdd:smart00263   80 CSKLLDDDITDDVKCAKKIVSDQ------GIDAWVAWKNHCQgEDLSQWIRGCG 127
LYZ cd00119
C-type lysozyme and alpha-lactalbumin; C-type lysozyme (chicken or conventional type, 1, ...
 596-723 1.05e-30

C-type lysozyme and alpha-lactalbumin; C-type lysozyme (chicken or conventional type, 1,4-beta-N-acetylmuramidase) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have primarily bacteriolytic function; hydrolysis of peptidoglycans of prokaryotic cell walls and transglycosylation. LA is a calcium-binding metalloprotein that is expressed exclusively in the mammary gland during lactation. LA is the regulatory subunit of the enzyme lactose synthase. The association of LA with the catalytic component of lactose synthase, galactosyltransferase, alters the acceptor substrate specificity of this glycosyltransferase, facilitating biosynthesis of lactose. Some lysozymes have evolved into digestive enzymes, both in mammals and invertebrates.


Pssm-ID: 340357  Cd Length: 122  Bit Score: 117.67  E-value: 1.05e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  596 KIYNRCELAKELYHRHKFPMREIPTWVCIAEHESSFNTAAVGKlNADGSEDHGLFQISDIYWCTHDQT--SGKACHIECD 673
Cdd:cd00119     1 KVFTRCELARLLKDIGGYGGISLPNWVCLMKHESGYDTQATNE-NNNGSTDYGLFQINSRYWCKDGQTpgARNICDISCS 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 386770748  674 RLLDSDISDDVQCIRTIHEEHtrlsgdGFNAWTVYNGHCRNQnLAKLSDC 723
Cdd:cd00119    80 KLLTDDITDAIMCAKKIVDDK------GIDAWVAWKNHCQNK-LRQYVSC 122
LYZ cd00119
C-type lysozyme and alpha-lactalbumin; C-type lysozyme (chicken or conventional type, 1, ...
 439-564 1.58e-30

C-type lysozyme and alpha-lactalbumin; C-type lysozyme (chicken or conventional type, 1,4-beta-N-acetylmuramidase) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have primarily bacteriolytic function; hydrolysis of peptidoglycans of prokaryotic cell walls and transglycosylation. LA is a calcium-binding metalloprotein that is expressed exclusively in the mammary gland during lactation. LA is the regulatory subunit of the enzyme lactose synthase. The association of LA with the catalytic component of lactose synthase, galactosyltransferase, alters the acceptor substrate specificity of this glycosyltransferase, facilitating biosynthesis of lactose. Some lysozymes have evolved into digestive enzymes, both in mammals and invertebrates.


Pssm-ID: 340357  Cd Length: 122  Bit Score: 116.90  E-value: 1.58e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  439 KVYNRCELAQELYFSHKFPMQDLATWVCIAEHESSFNTTAVGRlNADGSADHGLFQISDLYWCT--HNDGGGKGCHIDCN 516
Cdd:cd00119     1 KVFTRCELARLLKDIGGYGGISLPNWVCLMKHESGYDTQATNE-NNNGSTDYGLFQINSRYWCKdgQTPGARNICDISCS 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 386770748  517 RLLDSDITDDVKCVRTIHEEHtrisgdGFTAWTVYNGHCRQKTRADVA 564
Cdd:cd00119    80 KLLTDDITDAIMCAKKIVDDK------GIDAWVAWKNHCQNKLRQYVS 121
Lys pfam00062
C-type lysozyme/alpha-lactalbumin family; Alpha-lactalbumin is the regulatory subunit of ...
 185-312 3.44e-28

C-type lysozyme/alpha-lactalbumin family; Alpha-lactalbumin is the regulatory subunit of lactose synthase, changing the substrate specificity of galactosyltransferase from N-acetylglucosamine to glucose. C-type lysozymes are secreted bacteriolytic enzymes that cleave the peptidoglycan of bacterial cell walls. Structure is a multi-domain, mixed alpha and beta fold, containing four conserved disulfide bonds.


Pssm-ID: 395016  Cd Length: 123  Bit Score: 110.59  E-value: 3.44e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   185 KIYSRCELAQELyyqHKLPMP-----QIPTWVCIAQHESSFNTAAVGrlNADGSADHGLFQISDLFWCTHEQ--RAGKGC 257
Cdd:pfam00062    1 KQFTRCELAREL---KKLGMDgyrgiSLAEWVCLAFHESGYDTQAIV--YNNGSTDYGIFQINDKYWCKDGKtpQSVNIC 75

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 386770748   258 HATCNQFLDSSIGDDVQCIRRIhqehtqISGDGFNAWTVYKRNClNQHYEQIAAC 312
Cdd:pfam00062   76 GISCDKLLDDDITDDIMCAKKI------LDPQGIDAWLAWKPHC-SEDLEQWIGC 123
LYZ_C cd16897
C-type lysozyme; C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase). ...
 185-305 7.65e-28

C-type lysozyme; C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase). In humans, lysozyme is found in a wide variety of tissue types and body fluids. It has bacteriolytic properties through the hydolysis of beta-1,4, glyocosidic linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan, as well as between N-acetyl-D-glucosamine residues in chitodextrins. This family also includes digestive stomach lysozyme, which allow ruminants to digest bacteria in the foregut. The mammalian enzyme is related to lysozyme found hen egg-whites and related species.


Pssm-ID: 340383  Cd Length: 126  Bit Score: 109.66  E-value: 7.65e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  185 KIYSRCELAQEL------YYQHKlpmpQIPTWVCIAQHESSFNTAAVGRlNADGSADHGLFQISDLFWC-THEQRAGKGC 257
Cdd:cd16897     1 KIFSRCELARILkrggldGYRGY----SLANWVCLAYYESGFNTRATNE-NPDGSTDYGIFQINSRYWCnDGKTPSKNLC 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 386770748  258 HATCNQFLDSSIGDDVQCIRRIHQEHtqisgDGFNAWTVYKRNCLNQH 305
Cdd:cd16897    76 HISCSDLLNDDITDDIKCAKKIVKDP-----QGMGAWVAWRLHCEGRD 118
LYZ cd00119
C-type lysozyme and alpha-lactalbumin; C-type lysozyme (chicken or conventional type, 1, ...
 185-312 1.71e-27

C-type lysozyme and alpha-lactalbumin; C-type lysozyme (chicken or conventional type, 1,4-beta-N-acetylmuramidase) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have primarily bacteriolytic function; hydrolysis of peptidoglycans of prokaryotic cell walls and transglycosylation. LA is a calcium-binding metalloprotein that is expressed exclusively in the mammary gland during lactation. LA is the regulatory subunit of the enzyme lactose synthase. The association of LA with the catalytic component of lactose synthase, galactosyltransferase, alters the acceptor substrate specificity of this glycosyltransferase, facilitating biosynthesis of lactose. Some lysozymes have evolved into digestive enzymes, both in mammals and invertebrates.


Pssm-ID: 340357  Cd Length: 122  Bit Score: 108.43  E-value: 1.71e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  185 KIYSRCELAQELYYQHKLPMPQIPTWVCIAQHESSFNTAAVGRlNADGSADHGLFQISDLFWCTHEQ--RAGKGCHATCN 262
Cdd:cd00119     1 KVFTRCELARLLKDIGGYGGISLPNWVCLMKHESGYDTQATNE-NNNGSTDYGLFQINSRYWCKDGQtpGARNICDISCS 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 386770748  263 QFLDSSIGDDVQCIRRIHQEHtqisgdGFNAWTVYKRNCLNQhYEQIAAC 312
Cdd:cd00119    80 KLLTDDITDAIMCAKKIVDDK------GIDAWVAWKNHCQNK-LRQYVSC 122
Lys pfam00062
C-type lysozyme/alpha-lactalbumin family; Alpha-lactalbumin is the regulatory subunit of ...
 18-144 7.01e-26

C-type lysozyme/alpha-lactalbumin family; Alpha-lactalbumin is the regulatory subunit of lactose synthase, changing the substrate specificity of galactosyltransferase from N-acetylglucosamine to glucose. C-type lysozymes are secreted bacteriolytic enzymes that cleave the peptidoglycan of bacterial cell walls. Structure is a multi-domain, mixed alpha and beta fold, containing four conserved disulfide bonds.


Pssm-ID: 395016  Cd Length: 123  Bit Score: 103.65  E-value: 7.01e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748    18 KIFDRCELANLLQhRFGLPA---AQVATLVCIAQHSSDFNTAAFGGGVGLGGGShgLFQISDVYWCSP---PGQGKGCGL 91
Cdd:pfam00062    1 KQFTRCELARELK-KLGMDGyrgISLAEWVCLAFHESGYDTQAIVYNNGSTDYG--IFQINDKYWCKDgktPQSVNICGI 77

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 386770748    92 SCSRLRDDDIADDVLCVRKIyaehqrISGDGFTAWQAYDAYCRQDANSYVaGC 144
Cdd:pfam00062   78 SCDKLLDDDITDDIMCAKKI------LDPQGIDAWLAWKPHCSEDLEQWI-GC 123
LYZ_C cd16897
C-type lysozyme; C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase). ...
 18-144 6.35e-25

C-type lysozyme; C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase). In humans, lysozyme is found in a wide variety of tissue types and body fluids. It has bacteriolytic properties through the hydolysis of beta-1,4, glyocosidic linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan, as well as between N-acetyl-D-glucosamine residues in chitodextrins. This family also includes digestive stomach lysozyme, which allow ruminants to digest bacteria in the foregut. The mammalian enzyme is related to lysozyme found hen egg-whites and related species.


Pssm-ID: 340383  Cd Length: 126  Bit Score: 101.19  E-value: 6.35e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   18 KIFDRCELANLLqHRFGLPAAQVATL---VCIAQHSSDFNTAAFGGGVGLGGGSHgLFQISDVYWCSPpgqGK-----GC 89
Cdd:cd16897     1 KIFSRCELARIL-KRGGLDGYRGYSLanwVCLAYYESGFNTRATNENPDGSTDYG-IFQINSRYWCND---GKtpsknLC 75

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 386770748   90 GLSCSRLRDDDIADDVLCVRKIYAEHQrisgdGFTAWQAYDAYCR-QDANSYVAGC 144
Cdd:cd16897    76 HISCSDLLNDDITDDIKCAKKIVKDPQ-----GMGAWVAWRLHCEgRDLSRWLDGC 126
LYZ_LA cd16898
alpha lactalbumin; alpha-lactalbumin (lactose synthase B protein, LA) is a calcium-binding ...
 597-713 5.36e-24

alpha lactalbumin; alpha-lactalbumin (lactose synthase B protein, LA) is a calcium-binding metalloprotein that is expressed exclusively in the mammary gland during lactation. LA is the regulatory subunit of the enzyme lactose synthase. The association of LA with the catalytic component of lactose synthase, galactosyltransferase, alters the acceptor substrate specificity of this glycosyltransferase, facilitating biosynthesis of lactose.


Pssm-ID: 340384  Cd Length: 123  Bit Score: 98.27  E-value: 5.36e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  597 IYNRCELAKEL--YHRHKFPMREIPTWVCIAEHESSFNTAAVgkLNADGSEDHGLFQISDIYWCTHDQT--SGKACHIEC 672
Cdd:cd16898     2 IFTKCELSQILkeHGLDGFNGISLPEWICVTFHTSGYDTQAL--VYNNGSTEYGLFQISNKGWCDDSQEpvSRNICGISC 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 386770748  673 DRLLDSDISDDVQCIRTIHEEhtrlsGDGFNAWTVYNGHCR 713
Cdd:cd16898    80 SKLLDDDITDDIACAKKILAI-----PKGIDYWKAHKPFCR 115
LYZ cd00119
C-type lysozyme and alpha-lactalbumin; C-type lysozyme (chicken or conventional type, 1, ...
 18-142 7.93e-24

C-type lysozyme and alpha-lactalbumin; C-type lysozyme (chicken or conventional type, 1,4-beta-N-acetylmuramidase) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have primarily bacteriolytic function; hydrolysis of peptidoglycans of prokaryotic cell walls and transglycosylation. LA is a calcium-binding metalloprotein that is expressed exclusively in the mammary gland during lactation. LA is the regulatory subunit of the enzyme lactose synthase. The association of LA with the catalytic component of lactose synthase, galactosyltransferase, alters the acceptor substrate specificity of this glycosyltransferase, facilitating biosynthesis of lactose. Some lysozymes have evolved into digestive enzymes, both in mammals and invertebrates.


Pssm-ID: 340357  Cd Length: 122  Bit Score: 98.03  E-value: 7.93e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   18 KIFDRCELANLLQHRFGLPAAQVATLVCIAQHSSDFNTAAfGGGVGLGGGSHGLFQISDVYWCSP---PGQGKGCGLSCS 94
Cdd:cd00119     1 KVFTRCELARLLKDIGGYGGISLPNWVCLMKHESGYDTQA-TNENNNGSTDYGLFQINSRYWCKDgqtPGARNICDISCS 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 386770748   95 RLRDDDIADDVLCVRKIYAEHqrisgdGFTAWQAYDAYCRQDANSYVA 142
Cdd:cd00119    80 KLLTDDITDAIMCAKKIVDDK------GIDAWVAWKNHCQNKLRQYVS 121
LYZ_LA cd16898
alpha lactalbumin; alpha-lactalbumin (lactose synthase B protein, LA) is a calcium-binding ...
 441-558 1.11e-22

alpha lactalbumin; alpha-lactalbumin (lactose synthase B protein, LA) is a calcium-binding metalloprotein that is expressed exclusively in the mammary gland during lactation. LA is the regulatory subunit of the enzyme lactose synthase. The association of LA with the catalytic component of lactose synthase, galactosyltransferase, alters the acceptor substrate specificity of this glycosyltransferase, facilitating biosynthesis of lactose.


Pssm-ID: 340384  Cd Length: 123  Bit Score: 94.81  E-value: 1.11e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  441 YNRCELAQEL--YFSHKFPMQDLATWVCIAEHESSFNTTAVgrLNADGSADHGLFQISDLYWC--THNDGGGKGCHIDCN 516
Cdd:cd16898     3 FTKCELSQILkeHGLDGFNGISLPEWICVTFHTSGYDTQAL--VYNNGSTEYGLFQISNKGWCddSQEPVSRNICGISCS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 386770748  517 RLLDSDITDDVKCVRTIHEEhtrisGDGFTAWTVYNGHCRQK 558
Cdd:cd16898    81 KLLDDDITDDIACAKKILAI-----PKGIDYWKAHKPFCRED 117
LYZ_LA cd16898
alpha lactalbumin; alpha-lactalbumin (lactose synthase B protein, LA) is a calcium-binding ...
 186-302 3.21e-21

alpha lactalbumin; alpha-lactalbumin (lactose synthase B protein, LA) is a calcium-binding metalloprotein that is expressed exclusively in the mammary gland during lactation. LA is the regulatory subunit of the enzyme lactose synthase. The association of LA with the catalytic component of lactose synthase, galactosyltransferase, alters the acceptor substrate specificity of this glycosyltransferase, facilitating biosynthesis of lactose.


Pssm-ID: 340384  Cd Length: 123  Bit Score: 90.57  E-value: 3.21e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  186 IYSRCELAQELYyQHKLPMPQ---IPTWVCIAQHESSFNTAAVgrLNADGSADHGLFQISDLFWCTHEQ--RAGKGCHAT 260
Cdd:cd16898     2 IFTKCELSQILK-EHGLDGFNgisLPEWICVTFHTSGYDTQAL--VYNNGSTEYGLFQISNKGWCDDSQepVSRNICGIS 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 386770748  261 CNQFLDSSIGDDVQCIRRIHQEhtqisGDGFNAWTVYKRNCL 302
Cdd:cd16898    79 CSKLLDDDITDDIACAKKILAI-----PKGIDYWKAHKPFCR 115
LYZ_LA cd16898
alpha lactalbumin; alpha-lactalbumin (lactose synthase B protein, LA) is a calcium-binding ...
 19-136 5.42e-21

alpha lactalbumin; alpha-lactalbumin (lactose synthase B protein, LA) is a calcium-binding metalloprotein that is expressed exclusively in the mammary gland during lactation. LA is the regulatory subunit of the enzyme lactose synthase. The association of LA with the catalytic component of lactose synthase, galactosyltransferase, alters the acceptor substrate specificity of this glycosyltransferase, facilitating biosynthesis of lactose.


Pssm-ID: 340384  Cd Length: 123  Bit Score: 89.80  E-value: 5.42e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   19 IFDRCELANLLQHRF--GLPAAQVATLVCIAQHSSDFNTAAFGGGVGLGGGShgLFQISDVYWC----SPPGQGKgCGLS 92
Cdd:cd16898     2 IFTKCELSQILKEHGldGFNGISLPEWICVTFHTSGYDTQALVYNNGSTEYG--LFQISNKGWCddsqEPVSRNI-CGIS 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 386770748   93 CSRLRDDDIADDVLCVRKIYAEhqrisGDGFTAWQAYDAYCRQD 136
Cdd:cd16898    79 CSKLLDDDITDDIACAKKILAI-----PKGIDYWKAHKPFCRED 117
LT_IagB-like cd13400
Escherichia coli invasion protein IagB and similar proteins; Lytic transglycosylase-like ...
 206-241 1.71e-04

Escherichia coli invasion protein IagB and similar proteins; Lytic transglycosylase-like protein, similar to Escherichia coli invasion protein IagB. IagB is encoded within a pathogenicity island in Salmonella enterica and has been shown to degrade polymeric peptidoglycan. IagB-like invasion proteins are implicated in the invasion of eukaryotic host cells by bacteria. Lytic transglycosylase (LT) catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Members of this family resemble the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.


Pssm-ID: 381603 [Multi-domain]  Cd Length: 109  Bit Score: 42.13  E-value: 1.71e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 386770748  206 QIPTWV--CIAQHESSFNTAAVGRlNADGSADHGLFQI 241
Cdd:cd13400     2 GVPPRLlrAIAKVESGFNPNAINR-NKNGSYDIGLMQI 38
LT_IagB-like cd13400
Escherichia coli invasion protein IagB and similar proteins; Lytic transglycosylase-like ...
 624-657 1.83e-04

Escherichia coli invasion protein IagB and similar proteins; Lytic transglycosylase-like protein, similar to Escherichia coli invasion protein IagB. IagB is encoded within a pathogenicity island in Salmonella enterica and has been shown to degrade polymeric peptidoglycan. IagB-like invasion proteins are implicated in the invasion of eukaryotic host cells by bacteria. Lytic transglycosylase (LT) catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Members of this family resemble the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.


Pssm-ID: 381603 [Multi-domain]  Cd Length: 109  Bit Score: 42.13  E-value: 1.83e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 386770748  624 IAEHESSFNTAAVGKlNADGSEDHGLFQISDIYW 657
Cdd:cd13400    11 IAKVESGFNPNAINR-NKNGSYDIGLMQINSIWL 43
PHA03255 PHA03255
BDLF3; Provisional
 937-1067 3.45e-04

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 43.74  E-value: 3.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  937 SVTTTTRKPQTASTTKPVSTTAKTTSLPLWSW--------QTSTTAKPTISESGNRYTTSTTRSVITNKPNthPTIAAVS 1008
Cdd:PHA03255   21 SLIWTSSGSSTASAGNVTGTTAVTTPSPSASGpstnqsttLTTTSAPITTTAILSTNTTTVTSTGTTVTPV--PTTSNAS 98

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 386770748 1009 RPTTraTTRSTNGPIRTTSQpGTYLNTPLSSrspirQSTIRSStvfttrSTTRPTIRST 1067
Cdd:PHA03255   99 TINV--TTKVTAQNITATEA-GTGTSTGVTS-----NVTTRSS------STTSATTRIT 143
PHA03255 PHA03255
BDLF3; Provisional
 934-1029 5.19e-04

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 43.35  E-value: 5.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  934 TKQSVTTTTrkpqtasTTKPVSTTA--KTTSLPLWSWQTSTTAKPTISESGN-RYTTSTTRSVITN-------KPNTHPT 1003
Cdd:PHA03255   55 TNQSTTLTT-------TSAPITTTAilSTNTTTVTSTGTTVTPVPTTSNASTiNVTTKVTAQNITAteagtgtSTGVTSN 127

                          90       100
                  ....*....|....*....|....*.
gi 386770748 1004 IAAVSRPTTRATTRSTNGpirTTSQP 1029
Cdd:PHA03255  128 VTTRSSSTTSATTRITNA---TTLAP 150
LT_IagB-like cd13400
Escherichia coli invasion protein IagB and similar proteins; Lytic transglycosylase-like ...
 467-495 5.98e-04

Escherichia coli invasion protein IagB and similar proteins; Lytic transglycosylase-like protein, similar to Escherichia coli invasion protein IagB. IagB is encoded within a pathogenicity island in Salmonella enterica and has been shown to degrade polymeric peptidoglycan. IagB-like invasion proteins are implicated in the invasion of eukaryotic host cells by bacteria. Lytic transglycosylase (LT) catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Members of this family resemble the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.


Pssm-ID: 381603 [Multi-domain]  Cd Length: 109  Bit Score: 40.59  E-value: 5.98e-04
                          10        20
                  ....*....|....*....|....*....
gi 386770748  467 IAEHESSFNTTAVGRlNADGSADHGLFQI 495
Cdd:cd13400    11 IAKVESGFNPNAINR-NKNGSYDIGLMQI 38
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
935-1068 7.29e-04

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 43.50  E-value: 7.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   935 KQSVTTTTRKPQ-TASTTKPVSTTAKTTSLPLWSWQTSTTAKPTISESGNRYTTSTTRSVI-----TNKPNTH-PTIAAV 1007
Cdd:pfam05539  169 KTAVTTSKTTSWpTEVSHPTYPSQVTPQSQPATQGHQTATANQRLSSTEPVGTQGTTTSSNpepqtEPPPSQRgPSGSPQ 248

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 386770748  1008 SRPTTRATTRSTNGPIRTTSQPGTYLNTPLSSRSPIRQSTIRSSTvfTTRSTTRPTIRSTT 1068
Cdd:pfam05539  249 HPPSTTSQDQSTTGDGQEHTQRRKTPPATSNRRSPHSTATPPPTT--KRQETGRPTPRPTA 307
PRK13335 PRK13335
superantigen-like protein SSL3; Reviewed;
934-1065 7.67e-04

superantigen-like protein SSL3; Reviewed;


Pssm-ID: 139494 [Multi-domain]  Cd Length: 356  Bit Score: 43.58  E-value: 7.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  934 TKQSVTTTTRKPQTASTTkpVSTTAKTTSLPLWSWQTSTTAKPTISESGNRYTTSTTRSVITNKPnTHPTIAAVSRPTTR 1013
Cdd:PRK13335   36 TKVDKVPTLKAERLAMIN--ITAGANSATTQAANTRQERTPKLEKAPNTNEEKTSASKIEKISQP-KQEEQKSLNISATP 112

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 386770748 1014 ATTRSTNGPIRTTSQPGTYLNTPLSSRSPIRQSTIRSSTvfttrsTTRPTIR 1065
Cdd:PRK13335  113 APKQEQSQTTTESTTPKTKVTTPPSTNTPQPMQSTKSDT------PQSPTIK 158
PHA03255 PHA03255
BDLF3; Provisional
 891-1042 7.73e-04

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 42.58  E-value: 7.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  891 SKPPSPSKSTQLVSRPYVSSDSFRNEVIKFTATSAAVATTASFTKQSV--TTTTRKPQTASTTKPVSTTAKTTSLPLWSW 968
Cdd:PHA03255   26 SSGSSTASAGNVTGTTAVTTPSPSASGPSTNQSTTLTTTSAPITTTAIlsTNTTTVTSTGTTVTPVPTTSNASTINVTTK 105

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386770748  969 QTSTTAKPTISESGNRYTTS---TTRSVITNKPNTHPTIAAVSRPTtrATTRSTNGPIRTTSQpgtyLNTPLSSRSP 1042
Cdd:PHA03255  106 VTAQNITATEAGTGTSTGVTsnvTTRSSSTTSATTRITNATTLAPT--LSSKGTSNATKTTAE----LPTVPDERQP 176
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 823-1261 2.14e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 42.60  E-value: 2.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   823 GAPVYSTKKPNYDHNPF-LKAPGSVTPSVKPSHASQEVKLHDSTSyaqnpflsllGKPIVPAQAPIK--PQSKPPSPSKS 899
Cdd:pfam05109  440 AAPNTTTGLPSSTHVPTnLTAPASTGPTVSTADVTSPTPAGTTSG----------ASPVTPSPSPRDngTESKAPDMTSP 509

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   900 TQLVSRPYVSSDSfrnevikftatsaavattasfTKQSVTTTTRKPQTASTTKPVSTTAKTTSLPLWSWQTSTTAKPTIS 979
Cdd:pfam05109  510 TSAVTTPTPNATS---------------------PTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPN 568

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   980 ES-GNRYTTSTTRSVITNKPN-THPTIAAVSrPTTRATTRSTNGpirTTSQPgTYLNTPLSSRSPIR--QSTIRSSTvfT 1055
Cdd:pfam05109  569 ATiPTLGKTSPTSAVTTPTPNaTSPTVGETS-PQANTTNHTLGG---TSSTP-VVTSPPKNATSAVTtgQHNITSSS--T 641

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  1056 TRSTTRPTirSTTHAISRPTSSPTTRPTTRLTTRPTTRTTTRASVSPTTRPTVGLTTYQPTRTPTSITRRPIYTTQKQYT 1135
Cdd:pfam05109  642 SSMSLRPS--SISETLSPSTSDNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTSQASGPGNSSTST 719

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  1136 TTTRATTPYPTVSKPTTRPSTTTRPLTTtryIPTtrqsvITQTTNRNSAIYLPRNNTISTNRSTTKSPYHYvsinkpttr 1215
Cdd:pfam05109  720 KPGEVNVTKGTPPKNATSPQAPSGQKTA---VPT-----VTSTGGKANSTTGGKHTTGHGARTSTEPTTDY--------- 782

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*...
gi 386770748  1216 stTSTRPSTTIRYSPTTRQPPTTRST--TRYSAITAFSTRQTSTTPRP 1261
Cdd:pfam05109  783 --GGDSTTPRTRYNATTYLPPSTSSKlrPRWTFTSPPVTTAQATVPVP 828
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 818-1125 3.62e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.83  E-value: 3.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   818 PPPTQGAPVYSTKKPNYDHNPFLK-APGSVTPSVKPSHASQEVKLHDSTSYAQNPFL------SLLGKPIVPAQAPIKPQ 890
Cdd:pfam05109  518 PNATSPTPAVTTPTPNATSPTLGKtSPTSAVTTPTPNATSPTPAVTTPTPNATIPTLgktsptSAVTTPTPNATSPTVGE 597

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   891 SKPPSPSKSTQL---VSRPYVSSDSfRNevikftATSAAVATTASFTKQSVTTTTRKPQTASTTKPVSTTAKTTS-LPLW 966
Cdd:pfam05109  598 TSPQANTTNHTLggtSSTPVVTSPP-KN------ATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTShMPLL 670

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   967 swqtsTTAKPTISESGNRYT--TSTTRSVITNKPNTHPtiaavsrpttrATTRSTNGP--IRTTSQPGtylNTPLSSRSP 1042
Cdd:pfam05109  671 -----TSAHPTGGENITQVTpaSTSTHHVSTSSPAPRP-----------GTTSQASGPgnSSTSTKPG---EVNVTKGTP 731

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748  1043 IRQSTirSSTVFTTRSTTRPTIRSTTHAISRPTSSPTTRPTTRLTTRPTTRTTTRASVSPTTRptVGLTTYQPTRTPTSI 1122
Cdd:pfam05109  732 PKNAT--SPQAPSGQKTAVPTVTSTGGKANSTTGGKHTTGHGARTSTEPTTDYGGDSTTPRTR--YNATTYLPPSTSSKL 807


                   ...
gi 386770748  1123 TRR 1125
Cdd:pfam05109  808 RPR 810
DUF316 pfam03761
Nematode trypsin-6-like family; This is a family of trypsin-6-like proteins found in nematodes ...
 575-664 9.64e-03

Nematode trypsin-6-like family; This is a family of trypsin-6-like proteins found in nematodes that are part of the chymotrypsin family S1, ie a serine peptidase. The C. elegans sequence UniProt:O01566 is trypsin-6: all the active site residues are present (His90, Asp168, Ser267).


Pssm-ID: 367641  Cd Length: 281  Bit Score: 39.72  E-value: 9.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386770748   575 EVAKPSKGNELVKKTSPTPKAKIYNRCELAKELYHRHKFPM-------REIPTW-VCIAEHESSFNTAAVGK---LNADG 643
Cdd:pfam03761  123 DIMDLSKKKGKNSFRDNITRAYVLNGCANTKSKFDLSAKPMlvelegpLEPNISyPCLADESTSLEKGDAVDvygIDSSG 202

                           90       100
                   ....*....|....*....|.
gi 386770748   644 SEDHGLFQISDIYWCTHDQTS 664
Cdd:pfam03761  203 ELKHRKLNIVNCYSNDLSIGT 223
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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