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Conserved domains on  [gi|24662634|ref|NP_648457|]
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Dpt-YFP repressor by overexpression, isoform B [Drosophila melanogaster]

Protein Classification

MADF domain-containing protein( domain architecture ID 10565669)

MADF (Myb/SANT-like domain in Adf-1) domain-containing protein resembles the 3 alpha-helix bundle of the DNA-binding Myb domains

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MADF_DNA_bdg pfam10545
Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 ...
 64-147 3.03e-18

Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 (MADF) is an approximately 80-amino-acid module that directs sequence specific DNA binding to a site consisting of multiple tri-nucleotide repeats. The MADF domain is found in one or more copies in eukaryotic and viral proteins and is often associated with the BESS domain. It is likely that the MADF domain is more closely related to the myb/SANT domain than it is to other HTH domains.


:

Pssm-ID: 463144  Cd Length: 84  Bit Score: 79.64  E-value: 3.03e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662634    64 FIEDYRRQRVLWDPNTKGYHIKQTKYEALKLLSQKYGTEI--RSIRSKIKSLRSSFHREHGKVLSgrNRGVIYQPMWFAY 141
Cdd:pfam10545   1 LIELVREHPCLWDRSHPDYRNRDARERAWEEIAEELGSDVpvEDCKKRWKNLRDQYRRELRRKRT--NSGELYKSRWYYY 78


                  ....*.
gi 24662634   142 EAIRFI 147
Cdd:pfam10545  79 EELSFL 84
 
Name Accession Description Interval E-value
MADF_DNA_bdg pfam10545
Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 ...
 64-147 3.03e-18

Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 (MADF) is an approximately 80-amino-acid module that directs sequence specific DNA binding to a site consisting of multiple tri-nucleotide repeats. The MADF domain is found in one or more copies in eukaryotic and viral proteins and is often associated with the BESS domain. It is likely that the MADF domain is more closely related to the myb/SANT domain than it is to other HTH domains.


Pssm-ID: 463144  Cd Length: 84  Bit Score: 79.64  E-value: 3.03e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662634    64 FIEDYRRQRVLWDPNTKGYHIKQTKYEALKLLSQKYGTEI--RSIRSKIKSLRSSFHREHGKVLSgrNRGVIYQPMWFAY 141
Cdd:pfam10545   1 LIELVREHPCLWDRSHPDYRNRDARERAWEEIAEELGSDVpvEDCKKRWKNLRDQYRRELRRKRT--NSGELYKSRWYYY 78


                  ....*.
gi 24662634   142 EAIRFI 147
Cdd:pfam10545  79 EELSFL 84
MADF smart00595
subfamily of SANT domain;
63-149 1.44e-13

subfamily of SANT domain;


Pssm-ID: 214738  Cd Length: 89  Bit Score: 66.23  E-value: 1.44e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662634     63 NFIEDYRRQRVLWDPNTKGYHIKQTKYEALKLLSQKYGTEIRSIRSKIKSLRSSFHREHGKVLSGRNRGVIYqPMWFAYE 142
Cdd:smart00595   1 RLIELVRERPCLWDRRHPDYRNKEEKRKAWEEIAEELGLSVEECKKRWKNLRDRYRRELKRLQNGKSGGGKK-SKWEYFD 79


                   ....*..
gi 24662634    143 AIRFILD 149
Cdd:smart00595  80 RLSFLRP 86
 
Name Accession Description Interval E-value
MADF_DNA_bdg pfam10545
Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 ...
 64-147 3.03e-18

Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 (MADF) is an approximately 80-amino-acid module that directs sequence specific DNA binding to a site consisting of multiple tri-nucleotide repeats. The MADF domain is found in one or more copies in eukaryotic and viral proteins and is often associated with the BESS domain. It is likely that the MADF domain is more closely related to the myb/SANT domain than it is to other HTH domains.


Pssm-ID: 463144  Cd Length: 84  Bit Score: 79.64  E-value: 3.03e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662634    64 FIEDYRRQRVLWDPNTKGYHIKQTKYEALKLLSQKYGTEI--RSIRSKIKSLRSSFHREHGKVLSgrNRGVIYQPMWFAY 141
Cdd:pfam10545   1 LIELVREHPCLWDRSHPDYRNRDARERAWEEIAEELGSDVpvEDCKKRWKNLRDQYRRELRRKRT--NSGELYKSRWYYY 78


                  ....*.
gi 24662634   142 EAIRFI 147
Cdd:pfam10545  79 EELSFL 84
MADF smart00595
subfamily of SANT domain;
63-149 1.44e-13

subfamily of SANT domain;


Pssm-ID: 214738  Cd Length: 89  Bit Score: 66.23  E-value: 1.44e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662634     63 NFIEDYRRQRVLWDPNTKGYHIKQTKYEALKLLSQKYGTEIRSIRSKIKSLRSSFHREHGKVLSGRNRGVIYqPMWFAYE 142
Cdd:smart00595   1 RLIELVRERPCLWDRRHPDYRNKEEKRKAWEEIAEELGLSVEECKKRWKNLRDRYRRELKRLQNGKSGGGKK-SKWEYFD 79


                   ....*..
gi 24662634    143 AIRFILD 149
Cdd:smart00595  80 RLSFLRP 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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