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Conserved domains on  [gi|24663212|ref|NP_648559|]
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tRNA splicing endonuclease subunit 54 [Drosophila melanogaster]

Protein Classification

tRNA-splicing endonuclease subunit SEN54 family protein( domain architecture ID 10584195)

tRNA-splicing endonuclease subunit SEN54 family protein is a non-catalytic subunit of the tRNA-splicing endonuclease complex, which is responsible for identification and cleavage of the splice sites in pre-tRNA

Gene Ontology:  GO:0000379|GO:0000214
PubMed:  25071838|16710424

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
tRNA_int_end_N2 pfam12928
tRNA-splicing endonuclease subunit sen54 N-term; This is an N-terminal family of archaeal and ...
 66-129 3.00e-15

tRNA-splicing endonuclease subunit sen54 N-term; This is an N-terminal family of archaeal and metazoan sen54 proteins that forms one of the tRNA-splicing endonuclease subunits.


:

Pssm-ID: 463754  Cd Length: 69  Bit Score: 69.89  E-value: 3.00e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24663212    66 LSVPRIERLGGRALAIWNEEQQVAEVKRKDGK-FENFGY-SEQGKLYLEYYEAMFLLEVGRLQLEY 129
Cdd:pfam12928   4 LSYERGHRLKSLVKAVWFPELRVALVPHPKGKfFKTMGRdDKKGRLWLLPEEALYLVERGSLDLYW 69
 
Name Accession Description Interval E-value
tRNA_int_end_N2 pfam12928
tRNA-splicing endonuclease subunit sen54 N-term; This is an N-terminal family of archaeal and ...
 66-129 3.00e-15

tRNA-splicing endonuclease subunit sen54 N-term; This is an N-terminal family of archaeal and metazoan sen54 proteins that forms one of the tRNA-splicing endonuclease subunits.


Pssm-ID: 463754  Cd Length: 69  Bit Score: 69.89  E-value: 3.00e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24663212    66 LSVPRIERLGGRALAIWNEEQQVAEVKRKDGK-FENFGY-SEQGKLYLEYYEAMFLLEVGRLQLEY 129
Cdd:pfam12928   4 LSYERGHRLKSLVKAVWFPELRVALVPHPKGKfFKTMGRdDKKGRLWLLPEEALYLVERGSLDLYW 69
SEN2 COG1676
tRNA splicing endonuclease subunit SEN34 [Translation, ribosomal structure and biogenesis]; ...
 74-168 3.08e-05

tRNA splicing endonuclease subunit SEN34 [Translation, ribosomal structure and biogenesis]; tRNA splicing endonuclease subunit SEN34 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441282  Cd Length: 173  Bit Score: 44.04  E-value: 3.08e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24663212  74 LGGRALaIWNEEQQvaevkrkDGKFENFGY---SEQGKLYLEYYEAMFLLEVGRLQLEYCGLVVSIEqAYVLLLGELESE 150
Cdd:COG1676   9 LGDRVV-VWDIDAA-------RELYEEGFYgkpLDKSPLQLSLIEALYLLEKGKLEVYDDGKELSFE-ELLEIARKVDPE 79

                        90
                ....*....|....*...
gi 24663212 151 RYTNYLVYSALSRSGYIV 168
Cdd:COG1676  80 FDRKYLVYRDLRDRGYVV 97
 
Name Accession Description Interval E-value
tRNA_int_end_N2 pfam12928
tRNA-splicing endonuclease subunit sen54 N-term; This is an N-terminal family of archaeal and ...
 66-129 3.00e-15

tRNA-splicing endonuclease subunit sen54 N-term; This is an N-terminal family of archaeal and metazoan sen54 proteins that forms one of the tRNA-splicing endonuclease subunits.


Pssm-ID: 463754  Cd Length: 69  Bit Score: 69.89  E-value: 3.00e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24663212    66 LSVPRIERLGGRALAIWNEEQQVAEVKRKDGK-FENFGY-SEQGKLYLEYYEAMFLLEVGRLQLEY 129
Cdd:pfam12928   4 LSYERGHRLKSLVKAVWFPELRVALVPHPKGKfFKTMGRdDKKGRLWLLPEEALYLVERGSLDLYW 69
SEN2 COG1676
tRNA splicing endonuclease subunit SEN34 [Translation, ribosomal structure and biogenesis]; ...
 74-168 3.08e-05

tRNA splicing endonuclease subunit SEN34 [Translation, ribosomal structure and biogenesis]; tRNA splicing endonuclease subunit SEN34 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441282  Cd Length: 173  Bit Score: 44.04  E-value: 3.08e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24663212  74 LGGRALaIWNEEQQvaevkrkDGKFENFGY---SEQGKLYLEYYEAMFLLEVGRLQLEYCGLVVSIEqAYVLLLGELESE 150
Cdd:COG1676   9 LGDRVV-VWDIDAA-------RELYEEGFYgkpLDKSPLQLSLIEALYLLEKGKLEVYDDGKELSFE-ELLEIARKVDPE 79

                        90
                ....*....|....*...
gi 24663212 151 RYTNYLVYSALSRSGYIV 168
Cdd:COG1676  80 FDRKYLVYRDLRDRGYVV 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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