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Conserved domains on  [gi|24663878|ref|NP_648658|]
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Tondu-domain-containing growth inhibitor, isoform B [Drosophila melanogaster]

Protein Classification

TDU domain-containing protein( domain architecture ID 10653833)

TDU domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TDU smart00711
Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.
 129-144 8.51e-05

Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.


:

Pssm-ID: 197839  Cd Length: 16  Bit Score: 39.00  E-value: 8.51e-05
                           10
                   ....*....|....*.
gi 24663878    129 MCDIDEHFRRSLGENY 144
Cdd:smart00711   1 TSVVDEHFRRALGGNW 16
TDU smart00711
Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.
 358-373 7.38e-04

Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.


:

Pssm-ID: 197839  Cd Length: 16  Bit Score: 36.30  E-value: 7.38e-04
                           10
                   ....*....|....*.
gi 24663878    358 EASVDDHFAKALGETW 373
Cdd:smart00711   1 TSVVDEHFRRALGGNW 16
VGLL4 super family cl21104
Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional ...
 105-144 2.63e-03

Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional enhancer factor (TEF-1) cofactors.


The actual alignment was detected with superfamily member pfam15245:

Pssm-ID: 464585  Cd Length: 216  Bit Score: 38.69  E-value: 2.63e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 24663878   105 RPSVITQAPPKRE---------------PPEQAHSTDMA-MCD--IDEHFRRSLGENY 144
Cdd:pfam15245 156 RPSVITCAPASNRncnlshcpvngcpslPPDYRRSSSTNtACDpvIEEHFRRSLGKNY 213
 
Name Accession Description Interval E-value
TDU smart00711
Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.
 129-144 8.51e-05

Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.


Pssm-ID: 197839  Cd Length: 16  Bit Score: 39.00  E-value: 8.51e-05
                           10
                   ....*....|....*.
gi 24663878    129 MCDIDEHFRRSLGENY 144
Cdd:smart00711   1 TSVVDEHFRRALGGNW 16
TDU smart00711
Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.
 358-373 7.38e-04

Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.


Pssm-ID: 197839  Cd Length: 16  Bit Score: 36.30  E-value: 7.38e-04
                           10
                   ....*....|....*.
gi 24663878    358 EASVDDHFAKALGETW 373
Cdd:smart00711   1 TSVVDEHFRRALGGNW 16
VGLL4 pfam15245
Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional ...
 105-144 2.63e-03

Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional enhancer factor (TEF-1) cofactors.


Pssm-ID: 464585  Cd Length: 216  Bit Score: 38.69  E-value: 2.63e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 24663878   105 RPSVITQAPPKRE---------------PPEQAHSTDMA-MCD--IDEHFRRSLGENY 144
Cdd:pfam15245 156 RPSVITCAPASNRncnlshcpvngcpslPPDYRRSSSTNtACDpvIEEHFRRSLGKNY 213
 
Name Accession Description Interval E-value
TDU smart00711
Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.
 129-144 8.51e-05

Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.


Pssm-ID: 197839  Cd Length: 16  Bit Score: 39.00  E-value: 8.51e-05
                           10
                   ....*....|....*.
gi 24663878    129 MCDIDEHFRRSLGENY 144
Cdd:smart00711   1 TSVVDEHFRRALGGNW 16
TDU smart00711
Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.
 358-373 7.38e-04

Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.


Pssm-ID: 197839  Cd Length: 16  Bit Score: 36.30  E-value: 7.38e-04
                           10
                   ....*....|....*.
gi 24663878    358 EASVDDHFAKALGETW 373
Cdd:smart00711   1 TSVVDEHFRRALGGNW 16
VGLL4 pfam15245
Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional ...
 105-144 2.63e-03

Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional enhancer factor (TEF-1) cofactors.


Pssm-ID: 464585  Cd Length: 216  Bit Score: 38.69  E-value: 2.63e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 24663878   105 RPSVITQAPPKRE---------------PPEQAHSTDMA-MCD--IDEHFRRSLGENY 144
Cdd:pfam15245 156 RPSVITCAPASNRncnlshcpvngcpslPPDYRRSSSTNtACDpvIEEHFRRSLGKNY 213
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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