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Conserved domains on  [gi|28571729|ref|NP_650453|]
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3-hydroxyisobutyryl-CoA hydrolase, isoform A [Drosophila melanogaster]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 11240944)

enoyl-CoA hydratase/isomerase family protein plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate; similar to Homo sapiens 3-hydroxyisobutyryl-CoA hydrolase and Cereibacter sphaeroides Enoyl-CoA hydratase

CATH:  3.90.226.10
EC:  3.1.2.-
Gene Ontology:  GO:0016790
PubMed:  18470480|11263873
SCOP:  4004188

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
55-374 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


:

Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 544.37  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729    55 GMIILNRPKALNAINLEMVRKIYKHLKKCEKSKS--LVIIKGTGDKAFCAGGDVRALVEA---GPTDESKSFFREEYSTN 129
Cdd:pfam16113   2 GVITLNRPKALNALNLEMVRALLAALKAWEDDPAvkLVVLKGAGERAFCAGGDVRALYEAakaGGGEAGRDFFREEYRLN 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   130 ALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLGLYLGLTGYRLRGA 209
Cdd:pfam16113  82 YLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNGA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   210 DVYYSGIATHYCESSKIPDLETALLNCP--DADDVPELLQKYH-SPPEKPFSLQPVLEQINKNFSADSVEGILENLQN-- 284
Cdd:pfam16113 162 DALAAGLATHYVPSARLPALEEALAALDwsDPADVDAVLAEFAeESDPPPSPLAAHREAIDRCFSADTVEEIIAALEAea 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   285 DGSEWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALLIDKDQKPQWQPTKLAD 364
Cdd:pfam16113 242 DGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPATLEE 321
                         330
                  ....*....|
gi 28571729   365 VTEEHVQWFF 374
Cdd:pfam16113 322 VTDEMVDAYF 331
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
55-374 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 544.37  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729    55 GMIILNRPKALNAINLEMVRKIYKHLKKCEKSKS--LVIIKGTGDKAFCAGGDVRALVEA---GPTDESKSFFREEYSTN 129
Cdd:pfam16113   2 GVITLNRPKALNALNLEMVRALLAALKAWEDDPAvkLVVLKGAGERAFCAGGDVRALYEAakaGGGEAGRDFFREEYRLN 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   130 ALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLGLYLGLTGYRLRGA 209
Cdd:pfam16113  82 YLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNGA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   210 DVYYSGIATHYCESSKIPDLETALLNCP--DADDVPELLQKYH-SPPEKPFSLQPVLEQINKNFSADSVEGILENLQN-- 284
Cdd:pfam16113 162 DALAAGLATHYVPSARLPALEEALAALDwsDPADVDAVLAEFAeESDPPPSPLAAHREAIDRCFSADTVEEIIAALEAea 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   285 DGSEWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALLIDKDQKPQWQPTKLAD 364
Cdd:pfam16113 242 DGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPATLEE 321
                         330
                  ....*....|
gi 28571729   365 VTEEHVQWFF 374
Cdd:pfam16113 322 VTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
43-375 6.31e-155

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 440.03  E-value: 6.31e-155
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   43 SSSVLATESSNK-GMIILNRPKALNAINLEMVRKIYKHLKKCEK--SKSLVIIKGTGDKAFCAGGDVRALVEA---GPTD 116
Cdd:PRK05617   1 TEDEVLAEVEGGvGVITLNRPKALNALSLEMIRAIDAALDAWEDddAVAAVVIEGAGERGFCAGGDIRALYEAaraGDPL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  117 ESKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLG 196
Cdd:PRK05617  81 AADRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGALG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  197 LYLGLTGYRLRGADVYYSGIATHYCESSKIPDLETALLNCP---DADDVPELLQKYHSPPEKPfSLQPVLEQINKNFSAD 273
Cdd:PRK05617 161 TYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRwdsGADVVDAALAAFATPAPAS-ELAAQRAWIDECFAGD 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  274 SVEGILENLQNDGSEWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALLIDKDQ 353
Cdd:PRK05617 240 TVEDIIAALEADGGEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAMLRSPDFVEGVRAVLIDKDR 319
                        330       340
                 ....*....|....*....|..
gi 28571729  354 KPQWQPTKLADVTEEHVQWFFR 375
Cdd:PRK05617 320 NPKWSPATLEDVTPEDVEAFFA 341
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
57-234 4.81e-51

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 169.28  E-value: 4.81e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  57 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGP-TDESKSFFREEYSTNALIG 133
Cdd:cd06558  12 ITLNRPEKRNALSLEMLDELAAALDEAEADPDVrvVVLTGAG-KAFCAGADLKELAALSDaGEEARAFIRELQELLRALL 90
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729 134 NYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYRLRGADVY 212
Cdd:cd06558  91 RLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGpARARELLLTGRRISAEEAL 170
                       170       180
                ....*....|....*....|..
gi 28571729 213 YSGIATHYCESSKIPDLETALL 234
Cdd:cd06558 171 ELGLVDEVVPDEELLAAALELA 192
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
57-348 3.64e-44

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 153.40  E-value: 3.64e-44
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  57 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIGN 134
Cdd:COG1024  12 ITLNRPEKLNALSLEMLAELAAALDEAEADPDVrvVVLTGAG-KAFCAGADLKELAAAADPEEARAFARGLQRLFRALRR 90
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729 135 YKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYRLRGADVYY 213
Cdd:COG1024  91 LPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGlARAKELLLTGRRIDAEEALE 170
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729 214 SGIATHYCESSkipdletallncpdaddvpELLQKyhsppekpfslqpvleqinknfsadsvegilenlqndgsewAKKT 293
Cdd:COG1024 171 LGLVNRVVPDD-------------------ELLAA-----------------------------------------ALAL 190
                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*
gi 28571729 294 LETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALL 348
Cdd:COG1024 191 AARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFL 245
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
57-194 2.17e-13

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 69.50  E-value: 2.17e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729    57 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIGN 134
Cdd:TIGR01929  16 ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIgvVILTGAGDKAFCSGGDQKVRGDYGYIDDSGVHRLNVLDVQRQIRT 95
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   135 YKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGK 194
Cdd:TIGR01929  96 CPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMARIVGQ 155
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
55-374 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 544.37  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729    55 GMIILNRPKALNAINLEMVRKIYKHLKKCEKSKS--LVIIKGTGDKAFCAGGDVRALVEA---GPTDESKSFFREEYSTN 129
Cdd:pfam16113   2 GVITLNRPKALNALNLEMVRALLAALKAWEDDPAvkLVVLKGAGERAFCAGGDVRALYEAakaGGGEAGRDFFREEYRLN 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   130 ALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLGLYLGLTGYRLRGA 209
Cdd:pfam16113  82 YLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNGA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   210 DVYYSGIATHYCESSKIPDLETALLNCP--DADDVPELLQKYH-SPPEKPFSLQPVLEQINKNFSADSVEGILENLQN-- 284
Cdd:pfam16113 162 DALAAGLATHYVPSARLPALEEALAALDwsDPADVDAVLAEFAeESDPPPSPLAAHREAIDRCFSADTVEEIIAALEAea 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   285 DGSEWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALLIDKDQKPQWQPTKLAD 364
Cdd:pfam16113 242 DGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPATLEE 321
                         330
                  ....*....|
gi 28571729   365 VTEEHVQWFF 374
Cdd:pfam16113 322 VTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
43-375 6.31e-155

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 440.03  E-value: 6.31e-155
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   43 SSSVLATESSNK-GMIILNRPKALNAINLEMVRKIYKHLKKCEK--SKSLVIIKGTGDKAFCAGGDVRALVEA---GPTD 116
Cdd:PRK05617   1 TEDEVLAEVEGGvGVITLNRPKALNALSLEMIRAIDAALDAWEDddAVAAVVIEGAGERGFCAGGDIRALYEAaraGDPL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  117 ESKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLG 196
Cdd:PRK05617  81 AADRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGALG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  197 LYLGLTGYRLRGADVYYSGIATHYCESSKIPDLETALLNCP---DADDVPELLQKYHSPPEKPfSLQPVLEQINKNFSAD 273
Cdd:PRK05617 161 TYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRwdsGADVVDAALAAFATPAPAS-ELAAQRAWIDECFAGD 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  274 SVEGILENLQNDGSEWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALLIDKDQ 353
Cdd:PRK05617 240 TVEDIIAALEADGGEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAMLRSPDFVEGVRAVLIDKDR 319
                        330       340
                 ....*....|....*....|..
gi 28571729  354 KPQWQPTKLADVTEEHVQWFFR 375
Cdd:PRK05617 320 NPKWSPATLEDVTPEDVEAFFA 341
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
46-385 3.26e-99

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 299.41  E-value: 3.26e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   46 VLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKS--LVIIKGTGdKAFCAGGDVRALVEAGPTDES-KSFF 122
Cdd:PLN02874  13 VLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSveLIIIKGAG-RAFSAGGDLKMFYDGRESDDScLEVV 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  123 REEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLGLYLGLT 202
Cdd:PLN02874  92 YRMYWLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLPGHLGEYLALT 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  203 GYRLRGADVYYSGIATHYCESSKIPDLETAL--LNCPDADDVPELLQKYHSPPE-KPFSLQPVLEQINKNFSADSVEGIL 279
Cdd:PLN02874 172 GARLNGKEMVACGLATHFVPSEKLPELEKRLlnLNSGDESAVQEAIEEFSKDVQaDEDSILNKQSWINECFSKDTVEEII 251
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  280 ENLQ----NDGSEWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRL---AVRHLERSDFKEGVRALLIDKD 352
Cdd:PLN02874 252 KAFEseasKTGNEWIKETLKGLRRSSPTGLKITLRSIREGRKQSLAECLKKEFRLtmnILRSTVSDDVYEGIRALVIDKD 331
                        330       340       350
                 ....*....|....*....|....*....|...
gi 28571729  353 QKPQWQPTKLADVTEEHVQWFFRKLPDTEELKL 385
Cdd:PLN02874 332 NAPKWNPSTLDEVTDEKVDLVFQPFKAREELQL 364
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
58-385 1.53e-91

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 281.10  E-value: 1.53e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   58 ILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRAL---VEAGPTDESKSFFREEYSTNALI 132
Cdd:PLN02851  56 ILNRPSSLNALTIPMVARLKRLYESWEENPDIgfVLMKGSG-RAFCSGADVVSLyhlINEGNVEECKLFFENLYKFVYLQ 134
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  133 GNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLGLYLGLTGYRLRGADVY 212
Cdd:PLN02851 135 GTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSRLPGYLGEYLALTGQKLNGVEMI 214
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  213 YSGIATHYCESSKIPDLETAL--LNCPDADDVPELLQKYHSP--PEKPFSLQPVlEQINKNFSADSVEGILENLQNDGS- 287
Cdd:PLN02851 215 ACGLATHYCLNARLPLIEERLgkLLTDDPAVIEDSLAQYGDLvyPDKSSVLHKI-ETIDKCFGHDTVEEIIEALENEAAs 293
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  288 ---EWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLER---SDFKEGVRALLIDKDQKPQWQPTK 361
Cdd:PLN02851 294 sydEWCKKALKKIKEASPLSLKVTLQSIREGRFQTLDQCLAREYRISLCGVSKwvsGDFCEGVRARLVDKDFAPKWDPPS 373
                        330       340
                 ....*....|....*....|....*
gi 28571729  362 LADVTEEHVQWFFRKLPDTE-ELKL 385
Cdd:PLN02851 374 LGEVSKDMVDCYFTPLDESEsELEL 398
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
42-382 4.53e-89

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 273.90  E-value: 4.53e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   42 SSSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKS--LVIIKGTGdKAFCAGGDVRALV---EAGPTD 116
Cdd:PLN02988   7 SQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSvkLVILKGHG-RAFCAGGDVAAVVrdiEQGNWR 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  117 ESKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLG 196
Cdd:PLN02988  86 LGANFFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFG 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  197 LYLGLTGYRLRGADVYYSGIATHYCESSKIPDLETALLNCPDADDV--PELLQKYHSPPE-KPFSLQPVLEQINKNFSAD 273
Cdd:PLN02988 166 EYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRIGSNDPTfaSTILDAYTQHPRlKPQSAYHRLDVIDRCFSRR 245
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  274 SVEGILENLQNDGSE----WAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLE---RSDFKEGVRA 346
Cdd:PLN02988 246 TVEEIISALEREATQeadgWISATIQALKKASPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKgeiSKDFVEGCRA 325
                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 28571729  347 LLIDKDQKPQWQPTKLADVTEEHVQWFFRKLPDTEE 382
Cdd:PLN02988 326 ILVDKDKNPKWEPRRLEDMKDSMVEQYFERVEEEEE 361
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
34-381 7.87e-78

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 245.36  E-value: 7.87e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   34 TMALSVRQSSSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVE 111
Cdd:PLN02157  27 SLKLTPEDLDYQVLVEGSGCSRTAILNRPPALNALTTHMGYRLQKLYKNWEEDPNIgfVMMKGSG-RAFCAGGDIVSLYH 105
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  112 ---AGPTDESKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFL 188
Cdd:PLN02157 106 lrkRGSPDAIREFFSSLYSFIYLLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNL 185
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  189 PRLQGKLGLYLGLTGYRLRGADVYYSGIATHYCESSKIPDLETAL--LNCPDADDVPELLQKYH--SPPEKPFSLQPVlE 264
Cdd:PLN02157 186 SHLPGRLGEYLGLTGLKLSGAEMLACGLATHYIRSEEIPVMEEQLkkLLTDDPSVVESCLEKCAevAHPEKTGVIRRI-D 264
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  265 QINKNFSADSVEGILENLQNDGSE----WAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHL---ER 337
Cdd:PLN02157 265 LLEKCFSHDTVEEIIDSLEIEAGRrkdtWCITTLRRLKESSPLSLKVALRSIREGRLQTLDQCLIREYRMSLQGLigpMS 344
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 28571729  338 SDFKEGVRALLIDKDQKPQWQPTKLADVTEEHVQWFFRKLPDTE 381
Cdd:PLN02157 345 GNFCEGVRARLIDKDEAPKWDPPSLEKVSEDMVDDYFCALTPTE 388
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
57-234 4.81e-51

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 169.28  E-value: 4.81e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  57 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGP-TDESKSFFREEYSTNALIG 133
Cdd:cd06558  12 ITLNRPEKRNALSLEMLDELAAALDEAEADPDVrvVVLTGAG-KAFCAGADLKELAALSDaGEEARAFIRELQELLRALL 90
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729 134 NYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYRLRGADVY 212
Cdd:cd06558  91 RLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGpARARELLLTGRRISAEEAL 170
                       170       180
                ....*....|....*....|..
gi 28571729 213 YSGIATHYCESSKIPDLETALL 234
Cdd:cd06558 171 ELGLVDEVVPDEELLAAALELA 192
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
57-348 3.64e-44

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 153.40  E-value: 3.64e-44
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  57 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIGN 134
Cdd:COG1024  12 ITLNRPEKLNALSLEMLAELAAALDEAEADPDVrvVVLTGAG-KAFCAGADLKELAAAADPEEARAFARGLQRLFRALRR 90
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729 135 YKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYRLRGADVYY 213
Cdd:COG1024  91 LPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGlARAKELLLTGRRIDAEEALE 170
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729 214 SGIATHYCESSkipdletallncpdaddvpELLQKyhsppekpfslqpvleqinknfsadsvegilenlqndgsewAKKT 293
Cdd:COG1024 171 LGLVNRVVPDD-------------------ELLAA-----------------------------------------ALAL 190
                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*
gi 28571729 294 LETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALL 348
Cdd:COG1024 191 AARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFL 245
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
57-346 9.29e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 107.26  E-value: 9.29e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   57 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGP--TDESKSFFReeysTNALI 132
Cdd:PRK06688  18 ITINRPDKKNALTAAMYQALADALEAAATDPAVrvVVLTGAG-RAFSAGGDIKDFPKAPPkpPDELAPVNR----FLRAI 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  133 GNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGklglylgltgyRLRGADVY 212
Cdd:PRK06688  93 AALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIG-----------RARAAEML 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  213 YSGiathycesskipdletallncpdaddvpellqkyhsppeKPFSLQPVLEQ--INKNFSADSVEGIlenlqndgsewA 290
Cdd:PRK06688 162 LLG---------------------------------------EPLSAEEALRIglVNRVVPAAELDAE-----------A 191
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 28571729  291 KKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRA 346
Cdd:PRK06688 192 DAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFREGATA 247
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
43-203 1.83e-25

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 103.68  E-value: 1.83e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   43 SSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVR---ALVEAGPTDE 117
Cdd:PRK05980   2 TDTVLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVraVILTGAGDRAFSAGADIHefsASVAAGADVA 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  118 SKSFFREEYSTNALIGNYKIPYIAIIDGITMGGG--VGLSVHgkYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-K 194
Cdd:PRK05980  82 LRDFVRRGQAMTARLEAFPKPVIAAVNGLAFGGGceITEAVH--LAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGrK 159

                 ....*....
gi 28571729  195 LGLYLGLTG 203
Cdd:PRK05980 160 RALELLLTG 168
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
49-216 2.65e-25

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 102.82  E-value: 2.65e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729    49 TESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGtGDKAFCAGGDVRALVEAGPTDESKsfFREEY 126
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVraVVLTG-GDKAFCAGADLKEMYGEGPAHQAL--YRENV 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   127 STN-ALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGK-LGLYLGLTGY 204
Cdd:pfam00378  78 LDLwTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHsKAMEMLLLGR 157
                         170
                  ....*....|..
gi 28571729   205 RLRGADVYYSGI 216
Cdd:pfam00378 158 RISAQEALKWGL 169
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
55-233 3.18e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 102.89  E-value: 3.18e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   55 GMIILNRPKALNAINLEMVRKIYKHLK--KCEKSKSLVIIKGTGDKAFCAGGDV--RALVEAGPTDESKSFFREeysTNA 130
Cdd:PRK07657  15 VKITLNRPRAANALSLALLEELQNILTqiNEEANVRVVILTGAGEKAFCAGADLkeRAGMNEEQVRHAVSLIRT---TME 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  131 LIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG----KLGLYlglTGYRL 206
Cdd:PRK07657  92 MVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGvgraKELIY---TGRRI 168
                        170       180
                 ....*....|....*....|....*..
gi 28571729  207 RGADVYYSGIATHYCESSKIpdLETAL 233
Cdd:PRK07657 169 SAQEAKEIGLVEFVVPAHLL--EEKAI 193
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
59-236 2.77e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 100.51  E-value: 2.77e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   59 LNRPKALNAINLEMVRKIYKHLKKCEKSKSL-VIIKGTGDKAFCAGGDVRALVEAGPTDESKSffREEYSTNAlIGNYKI 137
Cdd:PRK08138  23 LNRPEARNALNMEVRQQLAEHFTELSEDPDIrAIVLTGGEKVFAAGADIKEFATAGAIEMYLR--HTERYWEA-IAQCPK 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  138 PYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKL-GLYLGLTGYRLRGADVYYSGI 216
Cdd:PRK08138 100 PVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFkAMRMALTGCMVPAPEALAIGL 179
                        170       180
                 ....*....|....*....|
gi 28571729  217 ATHYCESSKIpdLETALLNC 236
Cdd:PRK08138 180 VSEVVEDEQT--LPRALELA 197
PLN02600 PLN02600
enoyl-CoA hydratase
59-221 3.55e-22

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 94.49  E-value: 3.55e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   59 LNRPKALNAINLEMVRKIYKHLKKCEK--SKSLVIIKGTGDKAFCAGGDVRALVEAGPTdESKSFFREEYSTNALIGNYK 136
Cdd:PLN02600  10 LDRPEAKNAIGKEMLRGLRSAFEKIQAdaSARVVMLRSSVPGVFCAGADLKERRKMSPS-EVQKFVNSLRSTFSSLEALS 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  137 IPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGK-LGLYLGLTGYRLRGADVYYSG 215
Cdd:PLN02600  89 IPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRsRAKELIFTGRRIGAREAASMG 168

                 ....*.
gi 28571729  216 IAtHYC 221
Cdd:PLN02600 169 LV-NYC 173
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
53-203 2.07e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 92.15  E-value: 2.07e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   53 NKGM---IILNRPKALNAINLEMVRKIYKHLKKCEK--SKSLVIIKGTGdKAFCAGGDVRALVEAGPTDESKSFF---RE 124
Cdd:PRK06072   6 SREGyaiVTMSRPDKLNALNLEMRNEFISKLKQINAdpKIRVVIVTGEG-RAFCVGADLSEFAPDFAIDLRETFYpiiRE 84
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 28571729  125 EYSTNalignyKIpYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLGLYLGLTG 203
Cdd:PRK06072  85 IRFSD------KI-YISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQRFYEILVLG 156
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
46-193 3.04e-20

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 89.04  E-value: 3.04e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   46 VLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAGPTdESKSF-- 121
Cdd:PRK05809   6 VILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVyaVILTGAGEKAFVAGADISEMKDLNEE-EGRKFgl 84
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 28571729  122 -----FREeystnalIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG 193
Cdd:PRK05809  85 lgnkvFRK-------LENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVG 154
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
44-190 1.05e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 84.70  E-value: 1.05e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   44 SSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL-VIIKGTGdKAFCAGGDVRALVEagPTDESKsfF 122
Cdd:PRK07659   6 ESVVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAESSAHiVVLRGNG-RGFSAGGDIKMMLS--SNDESK--F 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28571729  123 RE--EYSTNALIGNYKIP--YIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPR 190
Cdd:PRK07659  81 DGvmNTISEIVVTLYTMPklTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQK 152
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
55-209 2.52e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 80.86  E-value: 2.52e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   55 GMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTgDKAFCAGGDVRALveagptdESKSF---FREEYSTN 129
Cdd:PRK05862  15 GLITLNRPKALNALNDALMDELGAALAAFDADEGIgaIVITGS-EKAFAAGADIKEM-------ADLSFmdvYKGDYITN 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  130 -ALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKL-GLYLGLTGyRLR 207
Cdd:PRK05862  87 wEKVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAkAMDLCLTG-RMM 165

                 ..
gi 28571729  208 GA 209
Cdd:PRK05862 166 DA 167
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
43-234 1.15e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 79.36  E-value: 1.15e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   43 SSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAGPTDESKS 120
Cdd:PRK06127  10 TGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIrvVVLTGAGEKAFVSGADISQFEESRSDAEAVA 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  121 FFrEEYSTNA--LIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGsyfLPRLQGKLG-- 196
Cdd:PRK06127  90 AY-EQAVEAAqaALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDG---VKNLVDLVGps 165
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 28571729  197 --LYLGLTGYRLRGADVYYSGIATHYCESSkipDLETALL 234
Cdd:PRK06127 166 aaKDLFYTARRFDAAEALRIGLVHRVTAAD---DLETALA 202
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
57-206 2.48e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 78.16  E-value: 2.48e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   57 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAGPTDESKSFF---REEYSTNAl 131
Cdd:PRK06494  17 VTLNRPEVMNALHLDAHFELEEVFDDFAADPEQwvAIVTGAGDKAFSAGNDLKEQAAGGKRGWPESGFgglTSRFDLDK- 95
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 28571729  132 ignykiPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYRL 206
Cdd:PRK06494  96 ------PIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGlKRAMGMILTGRRV 165
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
57-233 8.19e-16

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 76.66  E-value: 8.19e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   57 IILNRPKAlNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAGPTDEsksffreEYSTNALIGN 134
Cdd:PRK03580  16 ITLDRPKA-NAIDAKTSFAMGEVFLNFRDDPELrvAIITGAGEKFFSAGWDLKAAAEGEAPDA-------DFGPGGFAGL 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  135 YKI-----PYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLP-RLQGKLGLYLGLTGYRLRG 208
Cdd:PRK03580  88 TEIfdldkPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPkRLPPAIANEMVMTGRRMDA 167
                        170       180
                 ....*....|....*....|....*
gi 28571729  209 ADVYYSGIATHYCESSKIPDLETAL 233
Cdd:PRK03580 168 EEALRWGIVNRVVPQAELMDRAREL 192
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
43-218 9.02e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 76.30  E-value: 9.02e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   43 SSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAgPTDESKS 120
Cdd:PRK05870   2 MDPVLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVhaLVVTGAG-KAFCAGADLTALGAA-PGRPAED 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  121 FFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYL 199
Cdd:PRK05870  80 GLRRIYDGFLAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGpQVARAA 159
                        170
                 ....*....|....*....
gi 28571729  200 GLTGYRLRGADVYYSGIAT 218
Cdd:PRK05870 160 LLFGMRFDAEAAVRHGLAL 178
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
59-222 3.51e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 74.92  E-value: 3.51e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   59 LNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVeAGPTDESKSFF-REEYSTN----AL 131
Cdd:PRK07509  18 LNRPDKMNALDFAMFEELIATIKRLKKDRGIraVILSGEG-GAFCAGLDVKSVA-SSPGNAVKLLFkRLPGNANlaqrVS 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  132 IG--NYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGK-LGLYLGLTGYRLRG 208
Cdd:PRK07509  96 LGwrRLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGLVRKdVARELTYTARVFSA 175
                        170
                 ....*....|....
gi 28571729  209 ADVYYSGIATHYCE 222
Cdd:PRK07509 176 EEALELGLVTHVSD 189
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
71-207 1.77e-14

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 74.93  E-value: 1.77e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   71 EMVRKIYKHLKKCEKSKSLVIIKGTGDkAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIGNYKIPYIAIIDGITMGG 150
Cdd:PRK11154  37 EQVRAILKQLREDKELKGVVFISGKPD-NFIAGADINMLAACKTAQEAEALARQGQQLFAEIEALPIPVVAAIHGACLGG 115
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  151 GVGLSVHGKYRVASD--RTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYRLR 207
Cdd:PRK11154 116 GLELALACHYRVCTDdpKTVLGLPEVQLGLLPGSGGTQRLPRLIGvSTALDMILTGKQLR 175
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
55-346 3.77e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 71.69  E-value: 3.77e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   55 GMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGPTDESKSFFREEYSTNALi 132
Cdd:PRK07260  13 ATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVrfLLINANG-KVFSVGGDLVEMKRAVDEDDVQSLVKIAELVNEI- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  133 gNYKI-----PYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYRL 206
Cdd:PRK07260  91 -SFAIkqlpkPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGlNRATHLAMTGEAL 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  207 RGADVYYSGIATHYCESSKipdLETALLNcpdaddvpellqkyhsppekpfslqpVLEQINKNfSADSVEGILENL-QND 285
Cdd:PRK07260 170 TAEKALEYGFVYRVAESEK---LEKTCEQ--------------------------LLKKLRRG-SSNSYAAIKSLVwESF 219
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 28571729  286 GSEWAKktletlskmsptsmkvtFRQLELGSQLSLAQclimeyrlavrhleRSDFKEGVRA 346
Cdd:PRK07260 220 FKGWED-----------------YAKLELALQESLAF--------------KEDFKEGVRA 249
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
56-194 4.18e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 71.59  E-value: 4.18e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   56 MIILNRPKALNAINLEMVRKIYKHLKKCEKSKSLVIIKGTGDKaFCAGGDVRALVEAGPTDesksFFREEYSTNA---LI 132
Cdd:PRK08150  14 TIGLNRPAKRNALNDGLIAALRAAFARLPEGVRAVVLHGEGDH-FCAGLDLSELRERDAGE----GMHHSRRWHRvfdKI 88
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28571729  133 GNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGK 194
Cdd:PRK08150  89 QYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGV 150
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
56-203 7.85e-14

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 70.57  E-value: 7.85e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   56 MIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVE----AGPTDESKSFFREeystn 129
Cdd:PRK09674  14 LLTLNRPEARNALNNALLTQLVNELEAAATDTSIgvCVITGNA-RFFAAGADLNEMAEkdlaATLNDPRPQLWQR----- 87
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28571729  130 alIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGK-LGLYLGLTG 203
Cdd:PRK09674  88 --LQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKsLASQMVLTG 160
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
57-194 2.17e-13

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 69.50  E-value: 2.17e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729    57 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIGN 134
Cdd:TIGR01929  16 ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIgvVILTGAGDKAFCSGGDQKVRGDYGYIDDSGVHRLNVLDVQRQIRT 95
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   135 YKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGK 194
Cdd:TIGR01929  96 CPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMARIVGQ 155
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
41-216 2.82e-13

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 68.95  E-value: 2.82e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   41 QSSSSVLATESSNKGMIILNRPkALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDV--RALVEAGPTD 116
Cdd:PRK06495   1 MMMSQLKLEVSDHVAVVTLDNP-PVNALSRELRDELIAVFDEISERPDVrvVVLTGAG-KVFCAGADLkgRPDVIKGPGD 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  117 ESKSFFREEYSTNALIGNYKiPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLfpdVGGSYFLPRLQGK-L 195
Cdd:PRK06495  79 LRAHNRRTRECFHAIRECAK-PVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL---AGGGKHAMRLFGHsL 154
                        170       180
                 ....*....|....*....|.
gi 28571729  196 GLYLGLTGYRLRGADVYYSGI 216
Cdd:PRK06495 155 TRRMMLTGYRVPAAELYRRGV 175
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
59-193 3.25e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 69.23  E-value: 3.25e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   59 LNRPKALNAIN--------LEMVRKIYKhlkkcEKSKSLVIIKGTGdKAFCAGGDVRALVE-----AGPTDESksffREE 125
Cdd:PRK09245  18 MNRPETRNALSdndavdalVAACAAINA-----DRSVRAVILTGAG-TAFSSGGNVKDMRArvgafGGSPADI----RQG 87
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 28571729  126 YSTN------ALIgNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG 193
Cdd:PRK09245  88 YRHGiqriplALY-NLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIG 160
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
42-206 7.38e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 68.02  E-value: 7.38e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   42 SSSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCE-KSKSLVIIKGTGdKAFCAG---GDVRALVEAGPTDE 117
Cdd:PRK08140   2 MYETILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVEdDGARALLLTGAG-RGFCAGqdlADRDVTPGGAMPDL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  118 SKS---FFreeystNALI---GNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRL 191
Cdd:PRK08140  81 GESietFY------NPLVrrlRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRL 154
                        170
                 ....*....|....*...
gi 28571729  192 QGK---LGlyLGLTGYRL 206
Cdd:PRK08140 155 VGMaraLG--LALLGEKL 170
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
57-193 1.29e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 67.72  E-value: 1.29e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   57 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAG------GDVRALVEAGPTDESKSFFREEYST 128
Cdd:PRK08260  17 ITLNRPDKLNAFTVTMARELIEAFDAADADDAVraVIVTGAG-RAFCAGadlsagGNTFDLDAPRTPVEADEEDRADPSD 95
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28571729  129 NAL----------IGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG 193
Cdd:PRK08260  96 DGVrdgggrvtlrIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRLVG 170
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
57-188 1.81e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 66.87  E-value: 1.81e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   57 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGptdeskSFFREEYSTNAL--- 131
Cdd:PRK05995  17 VTLNRPDVRNAFNETVIAELTAAFRALDADDSVraVVLAGAG-KAFCAGADLNWMKKMA------GYSDDENRADARrla 89
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28571729  132 -----IGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFL 188
Cdd:PRK05995  90 dmlraIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPYVI 151
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
57-219 2.17e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 66.54  E-value: 2.17e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   57 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSLVIIKGTG-DKAFCAGGDvraLVEAGptDESKSFFREEYSTN--ALIG 133
Cdd:PRK06190  17 LTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGaDPAFCAGLD---LKELG--GDGSAYGAQDALPNpsPAWP 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  134 NYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYRLRGADVY 212
Cdd:PRK06190  92 AMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGiGRARRMSLTGDFLDAADAL 171

                 ....*..
gi 28571729  213 YSGIATH 219
Cdd:PRK06190 172 RAGLVTE 178
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
42-279 3.24e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 65.78  E-value: 3.24e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   42 SSSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVeAG--PTDE 117
Cdd:PRK08252   1 MSDEVLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLsvGILTGAG-GTFCAGMDLKAFA-RGerPSIP 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  118 SKSF--FREEYSTNalignykiPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLP-RLQGK 194
Cdd:PRK08252  79 GRGFggLTERPPRK--------PLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPrRIPYH 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  195 LGLYLGLTGYRLRGADVYYSGIATHYCESSKIpdLETAL-------LNCPDA-DDVPELLQKYHS-PPEKPFSLQpvLEQ 265
Cdd:PRK08252 151 IAMELALTGDMLTAERAHELGLVNRLTEPGQA--LDAALelaeriaANGPLAvAASKRIVVESGDwSEDEMFARQ--REL 226
                        250
                 ....*....|....*
gi 28571729  266 INKNF-SADSVEGIL 279
Cdd:PRK08252 227 IAPVFtSADAKEGAT 241
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
57-172 3.42e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 66.17  E-value: 3.42e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   57 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAgptDESKSFFREEYSTNALIG- 133
Cdd:PRK06144  21 ITFNRPAARNAMTWAMYEGLAEICEAIAADPSIraVVLRGAGDKAFVAGTDIAQFRAF---STAEDAVAYERRIDRVLGa 97
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 28571729  134 --NYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMP 172
Cdd:PRK06144  98 leQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFP 138
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
43-190 9.19e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 64.63  E-value: 9.19e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   43 SSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDkAFCAGGDVRALVEAGPTDESks 120
Cdd:PRK07511   2 SAELLSRREGSTLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIraVVLTGAGG-FFCAGGNLNRLLENRAKPPS-- 78
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 28571729  121 fFREEySTNAL------IGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPR 190
Cdd:PRK07511  79 -VQAA-SIDGLhdwiraIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLAR 152
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
56-190 1.13e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 64.35  E-value: 1.13e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   56 MIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDkAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIG 133
Cdd:PRK07799  17 IVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIrsCILTGAGG-AFCAGMDLKAATKKPPGDSFKDGSYDPSRIDALLK 95
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  134 NYKI--PYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPdVGGSYF-LPR 190
Cdd:PRK07799  96 GRRLtkPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFP-MGGSAVrLVR 154
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
45-210 2.77e-11

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 65.24  E-value: 2.77e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729    45 SVLATESSNKGMIILNrpKALNAinlEMVRKIyKHLKKCEKSKSLVIIKGTGDkAFCAGGDVRALVEAGPTDESKSFFRE 124
Cdd:TIGR02441  24 AVVKIDSPNSKVNTLS--KELFA---EFKEVM-NELWTNEAIKSAVLISGKPG-SFVAGADIQMIAACKTAQEVTQLSQE 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   125 EYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASD--RTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGL 201
Cdd:TIGR02441  97 GQEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKdrKTLLGLPEVMLGLLPGAGGTQRLPKLTGvPAALDMML 176

                  ....*....
gi 28571729   202 TGYRLRgAD 210
Cdd:TIGR02441 177 TGKKIR-AD 184
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
90-194 2.03e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 60.82  E-value: 2.03e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   90 VIIKGTGDKAFCAGGDVRALVEAGPtDESKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLF 169
Cdd:PRK06143  55 LVLRGAGEKAFIGGADIKEMATLDQ-ASAEAFISRLRDLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQF 133
                         90       100
                 ....*....|....*....|....*
gi 28571729  170 AMPETAIGLfPDVGGSYFLPRLQGK 194
Cdd:PRK06143 134 GMPEVRVGI-PSVIHAALLPRLIGW 157
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
56-193 3.08e-10

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 60.19  E-value: 3.08e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   56 MIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTgDKAFCAGGDVRALVEAGPTDESKS-----FFReeyst 128
Cdd:PRK06023  18 VIRFNRPEKKNAITRAMYATMAKALKAADADDAIraHVFLGT-EGCFSAGNDMQDFLAAAMGGTSFGseildFLI----- 91
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28571729  129 nALIGNYKiPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG 193
Cdd:PRK06023  92 -ALAEAEK-PIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMG 154
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
57-210 3.41e-10

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 60.30  E-value: 3.41e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   57 IILNRPKALNAINLEMVRKIYKHLKKCEKSK--SLVIIKGTGDKaFCAGGDVRAL----VEAGPTDESKSFFREEYSTNA 130
Cdd:PLN02664  21 LNLNRPSQRNALSLDFFTEFPKALSSLDQNPnvSVIILSGAGDH-FCSGIDLKTLnsisEQSSSGDRGRSGERLRRKIKF 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  131 L------IGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGsyfLPRLQGKLG----LYLG 200
Cdd:PLN02664 100 LqdaitaIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGT---LQRLPSIVGygnaMELA 176
                        170
                 ....*....|
gi 28571729  201 LTGYRLRGAD 210
Cdd:PLN02664 177 LTGRRFSGSE 186
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
59-203 3.74e-10

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 59.96  E-value: 3.74e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   59 LNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALvEAGPtdeSKSFFREEYSTNA----LI 132
Cdd:PRK08139  26 LNRPQAFNALSEAMLAALQAALDAIAADPSVrvVVLAAAG-KAFCAGHDLKEM-RAAR---GLAYFRALFARCSrvmqAI 100
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 28571729  133 GNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLF---PDVGGSYFLPRlqgKLGLYLGLTG 203
Cdd:PRK08139 101 VALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPMVALSRNVPR---KQAMEMLLTG 171
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
55-194 4.06e-10

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 59.75  E-value: 4.06e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   55 GMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSLV---IIKGTGdKAFCAG----------GDVRALVEAGPTDES--K 119
Cdd:PRK05981  15 AILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKAEVrclVLTGAG-RGFCTGanlqgrgsggRESDSGGDAGAALETayH 93
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28571729  120 SFFReeystnaLIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGK 194
Cdd:PRK05981  94 PFLR-------RLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGK 161
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
57-348 4.21e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 60.10  E-value: 4.21e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   57 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSLVIIKGTGD-KAFCAGGDVRALVEAGPTDESKSFFREEYSTN---ALI 132
Cdd:PRK06210  19 ITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAgRGFCAGADMGELQTIDPSDGRRDTDVRPFVGNrrpDYQ 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  133 GNYKI------PYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYR 205
Cdd:PRK06210  99 TRYHFltalrkPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRLVGhANALDLLLSART 178
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  206 LRGADVYYSGIATHYCESSKIpdLETALlncPDADDVpellqkyhsppekpfslqpvleqinknfsADSVegilenlqnd 285
Cdd:PRK06210 179 FYAEEALRLGLVNRVVPPDEL--MERTL---AYAEDL-----------------------------ARNV---------- 214
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28571729  286 gsewakktletlskmSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALL 348
Cdd:PRK06210 215 ---------------SPASMAVIKRQLYEDAFQTLAEATARANREMHESLQRPDFIEGVASFL 262
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
59-239 6.84e-10

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 59.05  E-value: 6.84e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   59 LNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGPTDESKSF--FRE--EYSTNalI 132
Cdd:PRK05674  21 LSRADKNNAFNAQMIRELILALDQVQSDASLrfLLLRGRG-RHFSAGADLAWMQQSADLDYNTNLddARElaELMYN--L 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  133 GNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLGLYLGLTGYRLRGADVY 212
Cdd:PRK05674  98 YRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISPFVVKAIGERAARRYALTAERFDGRRAR 177
                        170       180       190
                 ....*....|....*....|....*....|..
gi 28571729  213 YSGIATHYCESSKIPD-----LETALLNCPDA 239
Cdd:PRK05674 178 ELGLLAESYPAAELEAqveawIANLLLNSPQA 209
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
57-358 7.09e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 58.88  E-value: 7.09e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   57 IILNRPKAlNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIGN 134
Cdd:PRK07658  15 ITLNHPPA-NALSSQVLHELSELLDQVEKDDNVrvVVIHGEG-RFFSAGADIKEFTSVTEAEQATELAQLGQVTFERVEK 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  135 YKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKL-GLYLGLTGYRLRGADVYY 213
Cdd:PRK07658  93 FSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAkALEMMLTSEPITGAEALK 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  214 SGIATHycesskipdletallncpdADDVPELLQKyhsppekpfslqpvleqinknfsadsvegilenlqndgsewAKKT 293
Cdd:PRK07658 173 WGLVNG-------------------VFPEETLLDD-----------------------------------------AKKL 192
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28571729  294 LETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALLidKDQKPQWQ 358
Cdd:PRK07658 193 AKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFTSEDAKEGVQAFL--EKRKPSFS 255
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
47-193 1.21e-09

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 59.88  E-value: 1.21e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   47 LATESSNKgmiilnrpkaLNAINLEMVRKIYKHLKKCEKSKSLVIikgTGDK-AFCAGGDVRALVE--AGPTDESKSFFR 123
Cdd:PRK11730  23 DAPGSVNK----------LDRATLASLGEALDALEAQSDLKGLLL---TSAKdAFIVGADITEFLSlfAAPEEELSQWLH 89
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 28571729  124 EEYST-NALiGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG 193
Cdd:PRK11730  90 FANSIfNRL-EDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIG 159
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
33-205 3.08e-09

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 57.38  E-value: 3.08e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   33 TTMALSVRQSSSSVLATessnkgmIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALV 110
Cdd:PRK07827   2 TPVDTLVRYAVDGGVAT-------LTLDSPHNRNALSARLVAQLHDGLRAAAADPAVraVVLTHTG-GTFCAGADLSEAG 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  111 EAGPTDESKSFFREEYSTNAL--IGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFL 188
Cdd:PRK07827  74 GGGGDPYDAAVARAREMTALLraIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLL 153
                        170
                 ....*....|....*...
gi 28571729  189 PRLQGK-LGLYLgLTGYR 205
Cdd:PRK07827 154 PRLSPRaAARYY-LTGEK 170
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
57-200 3.32e-09

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 57.28  E-value: 3.32e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   57 IILNRPKALNAINLEM---VRKIYKHLKKCEKSKSLVIiKGTGDkAFCAGGDVRALVeaGP-----TDESKSFFReeyST 128
Cdd:PRK08258  30 ITLNRPERKNPLTFESyaeLRDLFRELVYADDVKAVVL-TGAGG-NFCSGGDVHEII--GPltkmdMPELLAFTR---MT 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  129 NALIG---NYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLF-PDVGGSYFLPRLQGkLG-----LYL 199
Cdd:PRK08258 103 GDLVKamrACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLAgADMGACALLPRIIG-QGraselLYT 181

                 .
gi 28571729  200 G 200
Cdd:PRK08258 182 G 182
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
56-358 7.02e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 56.08  E-value: 7.02e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   56 MIILNRPKAlNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEA--GPTDESKSFFREEYSTnal 131
Cdd:PRK09076  15 ILTLNNPPA-NTWTADSLQALKQLVLELNADKDVyaLVITGDGEKFFSAGADLNLFADGdkAVAREMARRFGEAFEA--- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  132 IGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKlglylG------LTGYR 205
Cdd:PRK09076  91 LSAFRGVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGE-----GwakrmiLCGER 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  206 LrgadvyysgiathycesskipDLETAL---LncpdaddVPELLqkyhsppEKPFSLQPVLeqinknfsadsvegilenl 282
Cdd:PRK09076 166 V---------------------DAATALrigL-------VEEVV-------EKGEAREAAL------------------- 191
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 28571729  283 qndgsEWAKKtletLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALLiDKdQKPQWQ 358
Cdd:PRK09076 192 -----ALAQK----VANQSPSAVAACKTLIQAARNGPRAAALALERELFVDLFDTEDQREGVNAFL-EK-RAPQWK 256
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
59-191 8.07e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 55.84  E-value: 8.07e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   59 LNRPKALNAINLEMVRKIYKHLKKCEKSKS--LVIIKGTGdKAFCAGGDV---RALVEAGPTDESKSFFREEYSTNALIG 133
Cdd:PRK07468  20 LNRPEKHNALSARMIAELTTAARRLAADAAvrVVVLTGAG-KSFCAGGDLgwmRAQMTADRATRIEEARRLAMMLKALND 98
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 28571729  134 NYKiPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRL 191
Cdd:PRK07468  99 LPK-PLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARM 155
PLN02888 PLN02888
enoyl-CoA hydratase
41-193 2.95e-08

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 54.37  E-value: 2.95e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   41 QSSSSVLATESSNKGMII-LNRPKALNAINLEMVRKIYKHLKKC--EKSKSLVIIKGTGdKAFCAGGDVRAlveagPTDE 117
Cdd:PLN02888   6 VSENLILVPKSRNGIATItINRPKALNALTRPMMVELAAAFKRLdeDDSVKVIILTGSG-RAFCSGVDLTA-----AEEV 79
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 28571729  118 SKSFFR-EEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG 193
Cdd:PLN02888  80 FKGDVKdVETDPVAQMERCRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIG 156
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
56-193 5.96e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 53.68  E-value: 5.96e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   56 MIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRAlveAGPTDESKSFFREEYSTNAL-- 131
Cdd:PRK05864  22 LITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVrvVVLTGAG-RGFSSGADHKS---AGVVPHVEGLTRPTYALRSMel 97
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  132 -------IGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLF-PDVGGSYFLPRLQG 193
Cdd:PRK05864  98 lddvilaLRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTaSELGLSYLLPRAIG 167
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
53-180 1.88e-07

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 51.61  E-value: 1.88e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   53 NKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSLVIIKGTGDkAFCAGGDVRALVEAGPTDESKSFFREEYstnali 132
Cdd:PRK07112  13 DVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHAATIVVLEGLPE-VFCFGADFSAIAEKPDAGRADLIDAEPL------ 85
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 28571729  133 gnYKI-------PYIAI--IDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFP 180
Cdd:PRK07112  86 --YDLwhrlatgPYVTIahVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIP 140
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
49-178 2.45e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 51.18  E-value: 2.45e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   49 TESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSLVI-IKGTGdKAFCAGGDVRALVEAgptdesKSFFREEYS 127
Cdd:PRK07854   5 TRDGQVLTIELQRPERRNALNAELCEELREAVRKAVDESARAIvLTGQG-TVFCAGADLSGDVYA------DDFPDALIE 77
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 28571729  128 TNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGL 178
Cdd:PRK07854  78 MLHAIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGI 128
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
66-210 4.61e-07

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 50.35  E-value: 4.61e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   66 NAINLEMVRKIYKHLKKCEKSKSL--VIIKGTgDKAFCAGGDVRALVEAgpTDESKSFFREEYSTNALigNYKIPYIAII 143
Cdd:PRK07110  27 NAFSDELCDQLHEAFDTIAQDPRYkvVILTGY-PNYFATGGTQEGLLSL--QTGKGTFTEANLYSLAL--NCPIPVIAAM 101
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 28571729  144 DGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRlqgKLGLYLG----LTGYRLRGAD 210
Cdd:PRK07110 102 QGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPE---KLGLALGqemlLTARYYRGAE 169
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
57-193 1.28e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 49.20  E-value: 1.28e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   57 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRAL------VEAGPTDESKSFFREEY-- 126
Cdd:PRK06142  19 VTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVraVVLSGSG-KHFSYGIDLPAMagvfgqLGKDGLARPRTDLRREIlr 97
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  127 ---STNAlIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG 193
Cdd:PRK06142  98 lqaAINA-VADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRIIG 166
PLN02921 PLN02921
naphthoate synthase
57-193 2.36e-06

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 49.02  E-value: 2.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   57 IILNRPKALNAINLEMVRKIYKHLKKC--EKSKSLVIIKGTGDKAFCAGGDvRALVEAGPTDESKSFFReeysTNALIGN 134
Cdd:PLN02921  80 ITINRPERRNAFRPRTVKELQRAFNDArdDSSVGVIILTGKGTKAFCSGGD-QAVRGKDGYVGPDDAGR----LNVLDLQ 154
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28571729  135 YKI-----PYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFpDVG-GSYFLPRLQG 193
Cdd:PLN02921 155 IQIrrlpkPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSF-DAGyGSSIMARLVG 218
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
57-193 3.99e-06

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 47.97  E-value: 3.99e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   57 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAGPTDESK-------SFFReeys 127
Cdd:PRK07396  26 ITINRPEVRNAFRPKTVKEMIDAFADARDDDNIgvIILTGAGDKAFCSGGDQKVRGYGGYVDDDGvprlnvlDLQR---- 101
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 28571729  128 tnaLIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFpDVG-GSYFLPRLQG 193
Cdd:PRK07396 102 ---LIRTCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSF-DGGyGASYLARIVG 164
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
39-193 5.15e-06

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 47.14  E-value: 5.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   39 VRQSSSSVLATESSNKG--MIILNRPKAlNAINLEMVRKIYKHLKKCEKSKSL--VIIKGtGDKAFCAGGDVRAL----- 109
Cdd:PRK05869   1 MNEFVNVVVSDGSQDAGlaTLLLSRPPT-NALTRQVYREIVAAANELGRRDDVaaVILYG-GHEIFSAGDDMPELrtlsa 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  110 VEAGPTDESKsffREEYSTNALIGNykiPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLP 189
Cdd:PRK05869  79 QEADTAARVR---QQAVDAVAAIPK---PTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLT 152

                 ....
gi 28571729  190 RLQG 193
Cdd:PRK05869 153 RAAG 156
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
56-193 2.42e-05

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 45.34  E-value: 2.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   56 MIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKaFCAGGDvraLVEAGPTDESKSFFREEYSTN--AL 131
Cdd:PRK06563  11 LIGLDRPAKRNAFDSAMLDDLALALGEYEADDELrvAVLFAHGEH-FTAGLD---LADVAPKLAAGGFPFPEGGIDpwGT 86
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28571729  132 IGN-YKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG 193
Cdd:PRK06563  87 VGRrLSKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAG 149
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
42-233 7.77e-05

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 43.86  E-value: 7.77e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   42 SSSSVLATESSNK-GMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSLVII--KGTGDKAFCAGGDVRALVEAG--PTD 116
Cdd:PRK11423   1 MSMQYVNVVTINKiATITFNNPAKRNALSKVLIDDLMQALSDLNRPEIRVVIlrAPSGSKVWSAGHDIHELPSGGrdPLS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  117 ESKSFfreEYSTNAlIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGsyfLPRLQGKLG 196
Cdd:PRK11423  81 YDDPL---RQILRM-IQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSG---ILNFTNDAG 153
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 28571729  197 LYLG----LTGYRLRGADVYYSGIATHYCESSKIPDLETAL 233
Cdd:PRK11423 154 FHIVkemfFTASPITAQRALAVGILNHVVEVEELEDFTLQM 194
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
90-191 1.06e-04

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 43.42  E-value: 1.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729   90 VIIKGTGdKAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLF 169
Cdd:PRK07938  49 VVLRAEG-RGFNAGVDIKELQATPGFTALIDANRGCFAAFRAVYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATF 127
                         90       100
                 ....*....|....*....|..
gi 28571729  170 AMPETAIGLfpdVGGSYFLPRL 191
Cdd:PRK07938 128 GLPEVDRGA---LGAATHLQRL 146
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
57-116 1.08e-03

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 40.39  E-value: 1.08e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28571729   57 IILNRPKALNAINLEMVR---KIYKHLKKcEKSKSLVIIKGTGdKAFCAGGDVrALVEAGPTD 116
Cdd:PRK07327  25 IVLNGPGALNAADARMHRelaDIWRDVDR-DPDVRVVLIRGEG-KAFSAGGDL-ALVEEMADD 84
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
57-193 1.18e-03

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 40.19  E-value: 1.18e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729  57 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDK-----AFCAGGDVRALVEAGPTDESKsffreeystn 129
Cdd:COG0447  31 IAINRPEVRNAFRPETVDELYDALDHAREDPDVgvVLLTGNGPSkdggwAFCSGGDQRVRGRGGYVYEDG---------- 100
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28571729 130 alIGNYKI------------PYIAIIDGITMGGgvGLSVHgkyrVASDRTLFAmpETAIglF----PDVG------GSYF 187
Cdd:COG0447 101 --VGRLNIlevqrlirfmpkPVIAMVAGWAIGG--GHVLH----VVCDLTIAS--ENAR--FgqtgPDVGsfdagyGSAY 168

                ....*.
gi 28571729 188 LPRLQG 193
Cdd:COG0447 169 LARQVG 174
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
57-113 4.75e-03

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 38.48  E-value: 4.75e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 28571729   57 IILNRPKALNAINLEMVRKIYKHLKKCE--KSKSLVIIKGTGdKAFCAGGDVRALVEAG 113
Cdd:PRK08272  23 ITLNRPEKGNAITADTPLELRAAVERADldPGVHVILVSGAG-KGFCAGYDLSAYAEGS 80
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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