|
Name |
Accession |
Description |
Interval |
E-value |
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
28-444 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 730.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 28 VVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSLFDEVL 107
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 108 KNEAKGLQhLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSEKFK 187
Cdd:pfam00709 81 ELEERGID-VPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLL-DPEVFREKLE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 188 SIVATHVRLFPSIN---VDVEAELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSNC 264
Cdd:pfam00709 159 ALLELKNKLLEKLYgepLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 265 SIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVNG 344
Cdd:pfam00709 239 TAGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRING 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 345 YTCICLTKLDILDTLPEIKVAVAYkKPNGEKLDHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVRFLE 424
Cdd:pfam00709 319 VTGLALTKLDVLDGLDEIKVCVAY-ELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIE 397
|
410 420
....*....|....*....|
gi 21356033 425 SELSVPVRWVGVGKGRESII 444
Cdd:pfam00709 398 ELLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
26-444 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 654.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 26 VDVVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSLFDE 105
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 106 VLKNEAKGLqHLENRLIISDRAHLVFDFHQHVDGMQEAEKggksLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSEK 185
Cdd:smart00788 81 IEELEAKGV-DVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLF-DEEVLREK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 186 FKSIVATHVRLFPSIN----VDVEAELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTS 261
Cdd:smart00788 155 LEELLDYKNFLLKKLYgaepVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTS 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 262 SNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSL 341
Cdd:smart00788 235 SNTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVR 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 342 VNGYTCICLTKLDILDTLPEIKVAVAYKKpNGEKLDHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVR 421
Cdd:smart00788 315 INGITGLALTKLDVLDGLDEIKVCVAYKL-DGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIE 393
|
410 420
....*....|....*....|...
gi 21356033 422 FLESELSVPVRWVGVGKGRESII 444
Cdd:smart00788 394 RIEELVGVPVSIISTGPDREQTI 416
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
23-447 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 632.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 23 KSKVDVVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSL 102
Cdd:PTZ00350 11 KSKVVVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 103 FDEVLKNEAKGLqHLENRLIISDRAHLVFDFHQHVDGMQEAE--KGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFN 180
Cdd:PTZ00350 91 LEEIEQLTKKGI-NLLGRLYISDRAHLVFDLHQAIDGIQESEkgKGGTQIGTTKRGIGPCYSTKASRTGLRVGDLL-NFE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 181 LFSEKFKSIVATHVRLFPSINVDVEAELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVT 260
Cdd:PTZ00350 169 TFEKKYRKLVEKLQEQYNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIKEGKRVLVEGANATMLDIDFGTYPYVT 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 261 SSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTS 340
Cdd:PTZ00350 249 SSNTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALRYVQ 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 341 LVNGYTCICLTKLDILDTLPEIKVAVAYK-KPNGEKLDHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSY 419
Cdd:PTZ00350 329 MINGFDSINLTKLDVLSGLKEIKICVNYKnKGTGLEIGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENAQKY 408
|
410 420
....*....|....*....|....*...
gi 21356033 420 VRFLESELSVPVRWVGVGKGRESIINVH 447
Cdd:PTZ00350 409 VLFIEELLGVPIVWIGVGPNRENMIVKK 436
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
26-447 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 627.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 26 VDVVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSLFDE 105
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 106 VLKNEAKGLqHLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSEK 185
Cdd:COG0104 81 IDGLEARGV-DVRSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLL-DPEVLREK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 186 FKSIVATHVRLFPSIN----VDVEAELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTS 261
Cdd:COG0104 159 LEELLEYKNFLLEKLYgaepLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTS 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 262 SNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSL 341
Cdd:COG0104 239 SNTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVR 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 342 VNGYTCICLTKLDILDTLPEIKVAVAYKKpNGEKLDHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVR 421
Cdd:COG0104 319 INGLTGLALTKLDVLDGLDEIKVCVAYEL-DGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVE 397
|
410 420
....*....|....*....|....*.
gi 21356033 422 FLESELSVPVRWVGVGKGRESIINVH 447
Cdd:COG0104 398 RIEELLGVPISIVSVGPDREQTIVRR 423
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
25-444 |
0e+00 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 520.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 25 KVDVVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSLFD 104
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 105 EVLKNEAKGLqHLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGEllgdfnlfse 184
Cdd:cd03108 81 EIEELEKKGI-DVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD---------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 185 kfksivathvrlfpsinvdveaelarykdyadkvrPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSNC 264
Cdd:cd03108 150 -----------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSSNT 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 265 SIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVNG 344
Cdd:cd03108 195 TAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRING 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 345 YTCICLTKLDIldtlpeikvavaykkpngekldhfpgtiaelgnieveyavlpgwqtsteevrnfkelpeNAQSYVRFLE 424
Cdd:cd03108 275 LTELALTKLDV-----------------------------------------------------------NAQKYIERIE 295
|
410 420
....*....|....*....|
gi 21356033 425 SELSVPVRWVGVGKGRESII 444
Cdd:cd03108 296 ELLGVPITYISVGPDREQTI 315
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
28-447 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 512.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 28 VVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSLFDEvL 107
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKE-M 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 108 KNEAKGLQHLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLGDfNLFSEKFK 187
Cdd:TIGR00184 80 EYLEKRGISVRDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDD-EAFAEKAK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 188 SIVATHVRLF----PSINVDVEAELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSN 263
Cdd:TIGR00184 159 NILEYLNEQLvkyyKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSN 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 264 CSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVN 343
Cdd:TIGR00184 239 TTAGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLN 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 344 GYTCICLTKLDILDTLPEIKVAVAYKKpNGEKLDHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVRFL 423
Cdd:TIGR00184 319 GATQLALTKLDVLDGIDEIKVCVAYRM-KGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERI 397
|
410 420
....*....|....*....|....
gi 21356033 424 ESELSVPVRWVGVGKGRESIINVH 447
Cdd:TIGR00184 398 EELTGVPVTIISTGPEREQTIDLR 421
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
26-344 |
2.43e-32 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 124.40 E-value: 2.43e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 26 VDVVLGAQWGDEGKGKVVDMLA--SDVDIVCRCqGGNNAGHTVV-ANGTEFDFHLLPSGVVNEKCVSV-IGNGVVIHLPS 101
Cdd:NF038379 1 VDVVVDGQFGSTGKGLIAGYLAerAAPDVVVRA-AGPNAGHTYIdDEGRKFVHRMLPNGIVSPPLKQVlIGPGSEIDLEV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 102 LFDEVLKNEAKGlQHLENRLIISDRAHLVfDFHQHVDgmQEAEKGGKsLGTTKKGIGPAYSSKATRNGIRVGELLGDFNL 181
Cdd:NF038379 80 LREEIEELEDAG-HDVGKRLLIHEQATVI-ELHKHVE--EEAGPMTK-IGSTKKGIGAARAAKIRRNPSTLGDAEGDFGE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 182 FSEKFksivathvrlfpsINVDVEAELARYKDYadkvrpyvkdticflHTALRNGKTILVEGANAAMLDIDFGTYPYVTS 261
Cdd:NF038379 155 GAVRD-------------QPWEIAERVVDNALY---------------DFALQAAERIQIEGTQGYSLGLHAGFYPYCTS 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 262 SNCSIGGVLTGLGLPPQ--TIGEVIGVVKAYTTRVGD-----GPFPTE-QLNDIGdlLQTrgfEVGVTTKRKRRCGWLDI 333
Cdd:NF038379 207 RDCTPADFLADAGIPLPnvDAFKVVGTARTYPIRVAGwsgnsYPDQGEtTWEELG--LPE---ELTTVTKKVRRVGTFSA 281
|
330
....*....|.
gi 21356033 334 PLLKYTSLVNG 344
Cdd:NF038379 282 EQVREAVQANG 292
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
28-444 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 730.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 28 VVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSLFDEVL 107
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 108 KNEAKGLQhLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSEKFK 187
Cdd:pfam00709 81 ELEERGID-VPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLL-DPEVFREKLE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 188 SIVATHVRLFPSIN---VDVEAELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSNC 264
Cdd:pfam00709 159 ALLELKNKLLEKLYgepLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 265 SIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVNG 344
Cdd:pfam00709 239 TAGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRING 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 345 YTCICLTKLDILDTLPEIKVAVAYkKPNGEKLDHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVRFLE 424
Cdd:pfam00709 319 VTGLALTKLDVLDGLDEIKVCVAY-ELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIE 397
|
410 420
....*....|....*....|
gi 21356033 425 SELSVPVRWVGVGKGRESII 444
Cdd:pfam00709 398 ELLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
26-444 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 654.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 26 VDVVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSLFDE 105
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 106 VLKNEAKGLqHLENRLIISDRAHLVFDFHQHVDGMQEAEKggksLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSEK 185
Cdd:smart00788 81 IEELEAKGV-DVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLF-DEEVLREK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 186 FKSIVATHVRLFPSIN----VDVEAELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTS 261
Cdd:smart00788 155 LEELLDYKNFLLKKLYgaepVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTS 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 262 SNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSL 341
Cdd:smart00788 235 SNTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVR 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 342 VNGYTCICLTKLDILDTLPEIKVAVAYKKpNGEKLDHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVR 421
Cdd:smart00788 315 INGITGLALTKLDVLDGLDEIKVCVAYKL-DGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIE 393
|
410 420
....*....|....*....|...
gi 21356033 422 FLESELSVPVRWVGVGKGRESII 444
Cdd:smart00788 394 RIEELVGVPVSIISTGPDREQTI 416
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
23-447 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 632.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 23 KSKVDVVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSL 102
Cdd:PTZ00350 11 KSKVVVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 103 FDEVLKNEAKGLqHLENRLIISDRAHLVFDFHQHVDGMQEAE--KGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFN 180
Cdd:PTZ00350 91 LEEIEQLTKKGI-NLLGRLYISDRAHLVFDLHQAIDGIQESEkgKGGTQIGTTKRGIGPCYSTKASRTGLRVGDLL-NFE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 181 LFSEKFKSIVATHVRLFPSINVDVEAELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVT 260
Cdd:PTZ00350 169 TFEKKYRKLVEKLQEQYNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIKEGKRVLVEGANATMLDIDFGTYPYVT 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 261 SSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTS 340
Cdd:PTZ00350 249 SSNTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALRYVQ 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 341 LVNGYTCICLTKLDILDTLPEIKVAVAYK-KPNGEKLDHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSY 419
Cdd:PTZ00350 329 MINGFDSINLTKLDVLSGLKEIKICVNYKnKGTGLEIGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENAQKY 408
|
410 420
....*....|....*....|....*...
gi 21356033 420 VRFLESELSVPVRWVGVGKGRESIINVH 447
Cdd:PTZ00350 409 VLFIEELLGVPIVWIGVGPNRENMIVKK 436
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
26-447 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 627.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 26 VDVVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSLFDE 105
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 106 VLKNEAKGLqHLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSEK 185
Cdd:COG0104 81 IDGLEARGV-DVRSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLL-DPEVLREK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 186 FKSIVATHVRLFPSIN----VDVEAELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTS 261
Cdd:COG0104 159 LEELLEYKNFLLEKLYgaepLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTS 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 262 SNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSL 341
Cdd:COG0104 239 SNTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVR 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 342 VNGYTCICLTKLDILDTLPEIKVAVAYKKpNGEKLDHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVR 421
Cdd:COG0104 319 INGLTGLALTKLDVLDGLDEIKVCVAYEL-DGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVE 397
|
410 420
....*....|....*....|....*.
gi 21356033 422 FLESELSVPVRWVGVGKGRESIINVH 447
Cdd:COG0104 398 RIEELLGVPISIVSVGPDREQTIVRR 423
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
24-444 |
0e+00 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 621.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 24 SKVDVVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVV-ANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSL 102
Cdd:PLN02513 2 SQVSAVLGTQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYnDEGKKFALHLVPSGILNEKTTCVIGNGVVVHLPGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 103 FDEVLKNEAKGLQhLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLF 182
Cdd:PLN02513 82 FEEIDGLESNGVS-CEGRLLVSDRAHLLFDFHQEVDGLREAELAGSKIGTTKRGIGPAYSSKATRNGLRVGDLR-HMDTF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 183 SEKFKSIVATHVRLFPSINVD---VEAELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYV 259
Cdd:PLN02513 160 AEKLRELLADAAARFEGFEYDasmVEEEVEAYKKFAERLEPFITDTVHYLNEAIQAGKKILVEGAQATMLDIDFGTYPFV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 260 TSSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYT 339
Cdd:PLN02513 240 TSSNPSAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTELFGELGDLLREAGQEFGTTTGRPRRCGWLDIVALKYS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 340 SLVNGYTCICLTKLDILDTLPEIKVAVAYKKPNGEKLDHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSY 419
Cdd:PLN02513 320 CQINGFTSLNLTKLDVLSGLPEIKIGVAYKTPDGKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPAAAQAY 399
|
410 420
....*....|....*....|....*
gi 21356033 420 VRFLESELSVPVRWVGVGKGRESII 444
Cdd:PLN02513 400 VERIEELVGVPVHYIGVGPGRDALI 424
|
|
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
25-447 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 606.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 25 KVDVVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSLFD 104
Cdd:PRK01117 2 KNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 105 EVLKNEAKGLQhLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSE 184
Cdd:PRK01117 82 EIDELEARGVD-VRERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLL-DPETFAE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 185 KFKSIVATH----VRLFPSINVDVEAELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVT 260
Cdd:PRK01117 160 KLEENLEYKnfllTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 261 SSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTS 340
Cdd:PRK01117 240 SSNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 341 LVNGYTCICLTKLDILDTLPEIKVAVAYKKpNGEKLDHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYV 420
Cdd:PRK01117 320 RVNGLTGLALTKLDVLDGLEEIKICVAYEL-DGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYI 398
|
410 420
....*....|....*....|....*..
gi 21356033 421 RFLESELSVPVRWVGVGKGRESIINVH 447
Cdd:PRK01117 399 KRIEELTGVPISIISTGPDRDQTIILR 425
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
25-444 |
0e+00 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 520.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 25 KVDVVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSLFD 104
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 105 EVLKNEAKGLqHLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGEllgdfnlfse 184
Cdd:cd03108 81 EIEELEKKGI-DVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD---------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 185 kfksivathvrlfpsinvdveaelarykdyadkvrPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSNC 264
Cdd:cd03108 150 -----------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSSNT 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 265 SIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVNG 344
Cdd:cd03108 195 TAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRING 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 345 YTCICLTKLDIldtlpeikvavaykkpngekldhfpgtiaelgnieveyavlpgwqtsteevrnfkelpeNAQSYVRFLE 424
Cdd:cd03108 275 LTELALTKLDV-----------------------------------------------------------NAQKYIERIE 295
|
410 420
....*....|....*....|
gi 21356033 425 SELSVPVRWVGVGKGRESII 444
Cdd:cd03108 296 ELLGVPITYISVGPDREQTI 315
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
28-447 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 512.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 28 VVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSLFDEvL 107
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKE-M 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 108 KNEAKGLQHLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLGDfNLFSEKFK 187
Cdd:TIGR00184 80 EYLEKRGISVRDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDD-EAFAEKAK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 188 SIVATHVRLF----PSINVDVEAELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSN 263
Cdd:TIGR00184 159 NILEYLNEQLvkyyKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSN 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 264 CSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVN 343
Cdd:TIGR00184 239 TTAGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLN 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 344 GYTCICLTKLDILDTLPEIKVAVAYKKpNGEKLDHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVRFL 423
Cdd:TIGR00184 319 GATQLALTKLDVLDGIDEIKVCVAYRM-KGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERI 397
|
410 420
....*....|....*....|....
gi 21356033 424 ESELSVPVRWVGVGKGRESIINVH 447
Cdd:TIGR00184 398 EELTGVPVTIISTGPEREQTIDLR 421
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
27-444 |
2.49e-125 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 370.05 E-value: 2.49e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 27 DVVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSLFDEV 106
Cdd:PRK13787 4 SLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQTICVIGNGVVLDPLFFIEEC 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 107 LKNEAKGLQhLENRLIISDRAHLVFDFHQHVDGMQEAEKGG-KSLGTTKKGIGPAYSSKATRNGIRVGELLGdfNLFSEK 185
Cdd:PRK13787 84 DRLQKEGFP-VKDKLLLSDACHLLFPYHSQIDSARETTSSQeHKIGTTKKGIGICYADKMMRTGLRVGDLLD--KSYKRR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 186 FKSIVATH----VRLFPSINVDVEAELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTS 261
Cdd:PRK13787 161 LKHLVDEKnrelDKLYGMPPVSYNDINDGLKFFLSKVGKNIINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 262 SNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSL 341
Cdd:PRK13787 241 SNPTTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEVLRQKGGEFGATTGRPRRCGWFDVEMLKHSVR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 342 VNGYTCICLTKLDILDTLPEIKVAVAYKKpNGEKLDHFPGTIAElgNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVR 421
Cdd:PRK13787 321 INGITSIALTKIDILSDYDTIPVAVGYKL-NGKTLDCFPSQGLE--KVEPLYEEFPGWKDDISGINEFQKLPEKCKNYIS 397
|
410 420
....*....|....*....|...
gi 21356033 422 FLESELSVPVRWVGVGKGRESII 444
Cdd:PRK13787 398 ALEKWIGVKINLVSTGPDRKDTI 420
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
29-441 |
1.31e-120 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 357.58 E-value: 1.31e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 29 VLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHlPSLFDEVLK 108
Cdd:PRK13788 6 IIGAQWGDEGKGKVVDALAPEADFVVRYQGGANAGHTVVAKGKTFKLNLLPSGVLHPHATSVLGDGMVID-PFRFAEERE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 109 NEAKGlqHLENRLIISDRAHLVFDFHQHVDGmqeaekGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSEKFKS 188
Cdd:PRK13788 85 NLRAG--GLNPKLLISERAHLVLPHHKYVDG------RKNFVGTTGRGIGPAYSDRARRVGIRFGDLL-DEAVLRERVER 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 189 IVATHvrlfPSINVD-----VEAELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSN 263
Cdd:PRK13788 156 LLEAK----PNSTREagwdtVEKALADLAPMREILLPFIADTGSLLREAIREGKRVLFEGAQATLLDLNYGTYPYVTSSH 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 264 CSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRG----FEVGVTTKRKRRCGWLDIPLLKYT 339
Cdd:PRK13788 232 PTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEVFGEMAIRLRGKGgnpwDEFGTTTGRARRVGWLDLVLLKYA 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 340 SLVNGYTCICLTKLDILDTLPEIKVAVAYkKPNGekldhfpgtiaelgniEVEYAVLPGWQTsTEEVRNFKELPENAQSY 419
Cdd:PRK13788 312 CEVNGFDGLVLTKLDVLSGLEKVKVCVEY-DDDG----------------QPVYKELPGWGD-LDGVKSREALPKEAQAY 373
|
410 420
....*....|....*....|..
gi 21356033 420 VRFLESELSVPVRWVGVGKGRE 441
Cdd:PRK13788 374 LELIEETTGVPVVMFSTSPRRE 395
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
28-444 |
1.79e-117 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 350.25 E-value: 1.79e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 28 VVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVsVIGNGVVIHLPSLFDEVL 107
Cdd:PRK13786 4 IITGAQFGDEGKGKIVDLLAKDYDIVARFQGGDNAGHTVKVGDEVYKLHLIPSGFLLDARV-LIGPGVVLNPEVLAEEID 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 108 KNEAKGLQHLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKsLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSEKFK 187
Cdd:PRK13786 83 MLEKHGVKVDAEKLGIDAKTSIIMPYHIELDGLRESARTEK-IGTTKRGIGFAYIDKIARDEVRMSDLV-DKERLMRRLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 188 SIVATHVRLF------PSINVDvEAELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTS 261
Cdd:PRK13786 161 ELAPQKEKEIkelggdPSIVRD-EALIDKYLELGRQLAPYITDVSYEINKALDEGKSVLAEGAQGTHLDVIHGTQKFVTS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 262 SNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSL 341
Cdd:PRK13786 240 SSTIAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTELKDEAGEHLQDVGGEFGTTTGRPRRCGWFDLPLLKKAIY 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 342 VNGYTCICLTKLDILDTLPEIKVAVAYKKpNGEKLDHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVR 421
Cdd:PRK13786 320 LNGYTEIALTKLDVLTGLDPIKICVGYEL-DGEILDYPPELTSDLARCVPVYEELEGWSTDLTEVKAYEDLPENARNYVE 398
|
410 420
....*....|....*....|...
gi 21356033 422 FLESELSVPVRWVGVGKGRESII 444
Cdd:PRK13786 399 RLEELMGVPIKYISVGPGREQTF 421
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
29-444 |
2.31e-111 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 335.58 E-value: 2.31e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 29 VLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKcVSVIGNGVVIHLPSLFDEVLK 108
Cdd:PRK13785 5 IVGSQLGDEGKGGVVDLYGDAADVVVRYQGGDNAGHTVVHGGEEYKLSLVPSGAVRGK-IGVLGNGCVVNPETLFDEIDA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 109 NEAKGlqhLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSL--GTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSEKF 186
Cdd:PRK13785 84 LRERG---LDPDVRVAERAHVILPYHRVLDGIEEEAKSDSDLevGTTGRGIGPTYEDKAGRRGVRVGDLL-DPDVLRDRL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 187 KSIVATHVRLFPSI----------NVDVEAELARYKDYADKVRPYVKDTIC--FLHTALRNGKTILVEGANAAMLDIDFG 254
Cdd:PRK13785 160 EYVVPQKRALAEDVygldasetpeAFDVDALFEEYREYGERLAEEDMTVNAgdFLAERIDDGDNVMLEGAQGTSIDIDHG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 255 TYPYVTSSNCSIGGVLTGLGLPPQTI--GEVIGVVKAYTTRVGDGPFPTEQLNDIGDL---------------LQTRGFE 317
Cdd:PRK13785 240 NYPYVTSSNPTAGGAATGTGLGPTVVgqGEVVGIVKAYLSRVGSGPLPTELGGVEGDTpdeggrpdeeelatyIREEGGE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 318 VGVTTKRKRRCGWLDIPLLKYTSLVNGYTCICLTKLDILDTLPEIKVAVAYKKpNGEKLDHFPGTIAELGNIEVEYAVLP 397
Cdd:PRK13785 320 YGTVTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYEL-DGEELLTMPATTERWARCEPNFRSFD 398
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 21356033 398 GWQTSTEEV---RNFKELPENAQSYVRFLESELSVPVRWVGVGKGRESII 444
Cdd:PRK13785 399 GWPEVDWAAvaeEGYDALPENARTYLEYVSDELDTPIYAVGVGPGREETV 448
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
28-446 |
1.37e-110 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 331.68 E-value: 1.37e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 28 VVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVvaNGTEFDF--HLLPSGVVNEKCVSVIGNGVVIHLPSLFDE 105
Cdd:PRK13783 4 VIVGLQWGDEGKGKVVTYLSRYYDIVVRYSGGANAGHTV--NYGDFKVvhHLLPSADFKKNVGAAIGNGVVLDLEVLVEE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 106 VLKNEAKGLQhLENRLIISDRAHLVFDFHQHVDGMQEAEKGgKSLGTTKKGIGPAYSSKATRNGIRVGELlGDFNLFSEK 185
Cdd:PRK13783 82 LEELKEKFPD-YSGRIFISELAHVVLPVHKELDEIIESVRK-NAIGTTKRGIGPAYADKVMRVGVRLADL-FDEEKLREF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 186 FKSIVATHVRLFpSINVDVEAELARYKDYADKVRPYVKDTIcFLHTALRNgKTILVEGANAAMLDIDFGTYPYVTSSNCS 265
Cdd:PRK13783 159 LEKILSLYKKLY-GIEFDVEKMMEDLLTFYEKIKDLVVSPV-EIKRILEE-KSVLFEGTQGVLLDLDVGTYPYVTSSNCS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 266 IGGVLTGLGLPPQtIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVNGY 345
Cdd:PRK13783 236 TTGVSAGMGFPVK-VDEVIGVFKAYTTRVGEGPFPTELFGEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLRYAIEVSGV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 346 TCICLTKLDILDTLPEIKVAVAYKKpNGEKLDHfPGTIAELGNIEVEYAVLPGWQtSTEEVrNFKElpenaqsYVRFLES 425
Cdd:PRK13783 315 DSLVMTKADVLNGFEKIKVCVRYEI-GGKEVRD-PSSLRDLEKAEPVYEEFDGWK-SLEDK-NFLK-------FVDFIER 383
|
410 420
....*....|....*....|.
gi 21356033 426 ELSVPVRWVGVGKGRESIINV 446
Cdd:PRK13783 384 ETGRKIAYISTGPKIEEIVEV 404
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
28-444 |
2.07e-100 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 306.56 E-value: 2.07e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 28 VVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSLFDEVL 107
Cdd:PRK13784 5 VIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALDEEIT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 108 KNEAKGLQHLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKsLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSEKFK 187
Cdd:PRK13784 85 RLQAKGIAISAENLFVSESCTIITSYHKLLDAVRESNTSEK-IGTTGKGIGPAYEDKVSRKGIKFKHLF-DKDLLRSRLA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 188 SIVATHVRLFPSINV----DVEAELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSN 263
Cdd:PRK13784 163 ISLAEKETLFRDLYKveypTLEQEFDKLFALGQKLKQYAADTFSIIDQAIAAGKNVVYEGAQGVLLDVDYGTYPFVTSSN 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 264 CSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVN 343
Cdd:PRK13784 243 TSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLDLPLLKYSAKCS 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 344 GYTCICLTKLDILDTLPEIKVAVAYKKPNGEKLDHFPGtiaeLGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVRFL 423
Cdd:PRK13784 323 NLTSIALTKVDVLSDMDTLKVCIGYKYEGKEIYCAYPG----IDLYKVEPILVEMEPFSIDETVTKDNMPAALKTYLKTI 398
|
410 420
....*....|....*....|.
gi 21356033 424 ESELSVPVRWVGVGKGRESII 444
Cdd:PRK13784 399 ENHVGIPISSLAYGPSREQIL 419
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
26-446 |
6.57e-60 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 198.57 E-value: 6.57e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 26 VDVVLGAQWGDEGKGKVVDMLA-SD-VDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLpslf 103
Cdd:PRK04293 3 CTIVVGGFFGDEGKGKIIAYLAlKDkPSIIARGGVGPNAGHTVEYNGKKYGLRMIPSGFVNKDAKLAIGAGVLVDP---- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 104 dEVLKNEAKGLQhLENRLIISDRAHLVFDFHQhvdgmqEAEKGG----KSLGTTKKGIGPAYSSKAtrngIRVGELLGDF 179
Cdd:PRK04293 79 -EVLLKEVEELN-VGGRVFVDYRCGIIEEKHV------EEDRSDehlsKKIGSTGTGCGPANADRV----LRRLKLAKDV 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 180 nlfsekfksivathvrlfpsinvdveaelarykdyaDKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYV 259
Cdd:PRK04293 147 ------------------------------------EELEKYLTDVPEEVNEALDRGENVLIEGTQGFGLSLYYGTYPYV 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 260 TSSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTE-QLNDIgdllQTRGF-EVGVTTKRKRRCGWLDIPLLK 337
Cdd:PRK04293 191 TSKDTTASGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTElSLEEA----EKLGLvEYGTVTGRRRRVGPFDFELAR 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 338 YTSLVNGYTCICLTKLDILDtlPEIKvavaykkpngekldhfpgtiaelgnieveyavlpgwqtsteEVRNFKELPENAQ 417
Cdd:PRK04293 267 RAARINGATQIAITKLDKLD--KEAY-----------------------------------------GVTEYDKLPPEAK 303
|
410 420
....*....|....*....|....*....
gi 21356033 418 SYVRFLESELSVPVRWVGVGKGRESIINV 446
Cdd:PRK04293 304 KFIEEIEEELGVPVTLISTGPELEDTIDL 332
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
26-344 |
2.43e-32 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 124.40 E-value: 2.43e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 26 VDVVLGAQWGDEGKGKVVDMLA--SDVDIVCRCqGGNNAGHTVV-ANGTEFDFHLLPSGVVNEKCVSV-IGNGVVIHLPS 101
Cdd:NF038379 1 VDVVVDGQFGSTGKGLIAGYLAerAAPDVVVRA-AGPNAGHTYIdDEGRKFVHRMLPNGIVSPPLKQVlIGPGSEIDLEV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 102 LFDEVLKNEAKGlQHLENRLIISDRAHLVfDFHQHVDgmQEAEKGGKsLGTTKKGIGPAYSSKATRNGIRVGELLGDFNL 181
Cdd:NF038379 80 LREEIEELEDAG-HDVGKRLLIHEQATVI-ELHKHVE--EEAGPMTK-IGSTKKGIGAARAAKIRRNPSTLGDAEGDFGE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 182 FSEKFksivathvrlfpsINVDVEAELARYKDYadkvrpyvkdticflHTALRNGKTILVEGANAAMLDIDFGTYPYVTS 261
Cdd:NF038379 155 GAVRD-------------QPWEIAERVVDNALY---------------DFALQAAERIQIEGTQGYSLGLHAGFYPYCTS 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 262 SNCSIGGVLTGLGLPPQ--TIGEVIGVVKAYTTRVGD-----GPFPTE-QLNDIGdlLQTrgfEVGVTTKRKRRCGWLDI 333
Cdd:NF038379 207 RDCTPADFLADAGIPLPnvDAFKVVGTARTYPIRVAGwsgnsYPDQGEtTWEELG--LPE---ELTTVTKKVRRVGTFSA 281
|
330
....*....|.
gi 21356033 334 PLLKYTSLVNG 344
Cdd:NF038379 282 EQVREAVQANG 292
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
26-301 |
1.01e-16 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 82.79 E-value: 1.01e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 26 VDVVLGAQWGDEGKGKVVDMLASDVDIVC--RCQGGNNAGHTVVAN-GTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSL 102
Cdd:PTZ00351 171 VIMVAGAFFGDEGKGKTVDAVAHHPLCTCiaRVNSGENAGHTVYDKaGRKFVFNLAPSGLLLPGKRNYIGPECVMDPVSF 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 103 FD-EVLKNEAKGLQHlENRLIISDRAhLVFDFHQHVDGMqeaekGGKSLGTTKKGIGPAYSSKATRNGIRVGELLGDFNL 181
Cdd:PTZ00351 251 MEkEIIQLIDAGIDY-RDRLFIGNVC-IVTPYHKLLDLL-----GSAANSSTLKGMAPVHGSKVMKRGIRLDHIFNDDET 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356033 182 FSEKFKSIVATHVRLFPSINV---------------------DVEAELARYKD--------YADKVR-----PYVKDTIC 227
Cdd:PTZ00351 324 LRKRLEKDMDTYLGLLKVKNLsdadvvrlcreensdgvvrvpDYVIAFAQAKDkveflvklYRDRVRhnpdfPARCDVTY 403
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 21356033 228 FLHTALRNGKTILVEGANAAML-DIDFGTYPYVTSSNCSIGGVLTGLGLPPQTIGEVI-GVVKAY-TTRVGDGPFPT 301
Cdd:PTZ00351 404 ELHAAVLRGEKVLLEGPQSYWLsNARTKFWESTTSADTTAAGLLAASQLNFQKFKSVVlNVHKAPgSSRVGIGACPS 480
|
|
| |
