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Conserved domains on  [gi|24649667|ref|NP_651259|]
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uncharacterized protein Dmel_CG17780, isoform A [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DM4_12 super family cl11657
DM4/DM12 family; This family contains sequences derived from hypothetical proteins expressed ...
 133-220 2.69e-16

DM4/DM12 family; This family contains sequences derived from hypothetical proteins expressed by two insect species, D. melanogaster and A. gambiae. The region in question is approximately 115 amino acid residues long and contains four highly- conserved cysteine residues.


The actual alignment was detected with superfamily member smart00718:

Pssm-ID: 472236  Cd Length: 95  Bit Score: 71.59  E-value: 2.69e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649667    133 RLFKRDLFSKLETALDGHGFDGRACMLKSFCTAINDVDnpkQKSGMLFKMLKLIFRL-DEHDKRHMPHLREE-------- 203
Cdd:smart00718   3 DRSRRLLYEALENLLDQLGFNGRACLLRAICESAQKLD---DHRGLLGELLRIVLTPpDELEEVLDPDYREAyragragg 79

                           90
                   ....*....|....*..
gi 24649667    204 NCEQIMHsHCPLSFDSI 220
Cdd:smart00718  80 DCDRLYS-HCPLSLLLL 95
 
Name Accession Description Interval E-value
DM4_12 smart00718
DM4/DM12 family of domains in Drosophila melanogaster proteins of unknown function;
133-220 2.69e-16

DM4/DM12 family of domains in Drosophila melanogaster proteins of unknown function;


Pssm-ID: 214785  Cd Length: 95  Bit Score: 71.59  E-value: 2.69e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649667    133 RLFKRDLFSKLETALDGHGFDGRACMLKSFCTAINDVDnpkQKSGMLFKMLKLIFRL-DEHDKRHMPHLREE-------- 203
Cdd:smart00718   3 DRSRRLLYEALENLLDQLGFNGRACLLRAICESAQKLD---DHRGLLGELLRIVLTPpDELEEVLDPDYREAyragragg 79

                           90
                   ....*....|....*..
gi 24649667    204 NCEQIMHsHCPLSFDSI 220
Cdd:smart00718  80 DCDRLYS-HCPLSLLLL 95
DM4_12 pfam07841
DM4/DM12 family; This family contains sequences derived from hypothetical proteins expressed ...
 136-213 2.15e-15

DM4/DM12 family; This family contains sequences derived from hypothetical proteins expressed by two insect species, D. melanogaster and A. gambiae. The region in question is approximately 115 amino acid residues long and contains four highly- conserved cysteine residues.


Pssm-ID: 462285  Cd Length: 86  Bit Score: 68.86  E-value: 2.15e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649667   136 KRDLFSKLETALDGHGFDGRACMLKSFCTAINdvDNPKQKSGMLFKMLKLIFR----LDEHDKRHMPHLREE-------N 204
Cdd:pfam07841   1 RRDLYRKLEELLERYGFDGRACLLRAICEAAQ--RPLPENNGLLGELLHILFTpsssEDEELDDDDEYLEAEragrsgaD 78


                  ....*....
gi 24649667   205 CEQIMhSHC 213
Cdd:pfam07841  79 CAQLY-PEC 86
 
Name Accession Description Interval E-value
DM4_12 smart00718
DM4/DM12 family of domains in Drosophila melanogaster proteins of unknown function;
133-220 2.69e-16

DM4/DM12 family of domains in Drosophila melanogaster proteins of unknown function;


Pssm-ID: 214785  Cd Length: 95  Bit Score: 71.59  E-value: 2.69e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649667    133 RLFKRDLFSKLETALDGHGFDGRACMLKSFCTAINDVDnpkQKSGMLFKMLKLIFRL-DEHDKRHMPHLREE-------- 203
Cdd:smart00718   3 DRSRRLLYEALENLLDQLGFNGRACLLRAICESAQKLD---DHRGLLGELLRIVLTPpDELEEVLDPDYREAyragragg 79

                           90
                   ....*....|....*..
gi 24649667    204 NCEQIMHsHCPLSFDSI 220
Cdd:smart00718  80 DCDRLYS-HCPLSLLLL 95
DM4_12 pfam07841
DM4/DM12 family; This family contains sequences derived from hypothetical proteins expressed ...
 136-213 2.15e-15

DM4/DM12 family; This family contains sequences derived from hypothetical proteins expressed by two insect species, D. melanogaster and A. gambiae. The region in question is approximately 115 amino acid residues long and contains four highly- conserved cysteine residues.


Pssm-ID: 462285  Cd Length: 86  Bit Score: 68.86  E-value: 2.15e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649667   136 KRDLFSKLETALDGHGFDGRACMLKSFCTAINdvDNPKQKSGMLFKMLKLIFR----LDEHDKRHMPHLREE-------N 204
Cdd:pfam07841   1 RRDLYRKLEELLERYGFDGRACLLRAICEAAQ--RPLPENNGLLGELLHILFTpsssEDEELDDDDEYLEAEragrsgaD 78


                  ....*....
gi 24649667   205 CEQIMhSHC 213
Cdd:pfam07841  79 CAQLY-PEC 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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