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glycoprotein 93 [Drosophila melanogaster]
Protein Classification
List of domain hits
Name
Accession
Description
Interval
E-value
HSP90
pfam00183 Hsp90 protein;
257-748
0e+00
Hsp90 protein;
Pssm-ID: 459703
Cd Length: 516
Bit Score: 777.89
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 257 DF LEE DTVR EL IR KYS Q FINFPI RM W SS K TV E E EVP V EEE AKP E K s E DDV ED E D A KVEE AED E -- K P KTKKV SK T T W D W T 334
Cdd:pfam00183 1 EY LEE KKIK EL VK KYS E FINFPI YL W VE K EE E V EVP D EEE EEE E E - E EEE ED D D P KVEE EDE E ee K K KTKKV KE T V W E W E 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 335 L I N DS KPIWTR K P A EVTE D EY TS FYKSL T KD SSE PL TQT HF IA EGEV T FKSLL YV PK VQ P SES F NRY g T K SD NIKLYVRR 414
Cdd:pfam00183 80 L L N KT KPIWTR N P K EVTE E EY AE FYKSL S KD WED PL AVK HF SV EGEV E FKSLL FI PK RA P FDL F ENK - K K KN NIKLYVRR 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 415 VFITD E F N D MM P N YL S F IR GVVDSDDLPLNVSRETLQQ H K LI KVIKKKLVRK V LDM L K K I -- D KE A Y E KFWKEF ST N I KL 492
Cdd:pfam00183 159 VFITD D F E D LI P E YL N F VK GVVDSDDLPLNVSRETLQQ N K IL KVIKKKLVRK A LDM F K E I ae E KE D Y K KFWKEF GK N L KL 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 493 G VM ED P SNR SR LAKLLRF QT S NGKG - V TSL AE Y KE RMK AK Q E HIYYI A G ANRA EVE K SPF V ERL LS KGYEVLYL VEAV DE 571
Cdd:pfam00183 239 G II ED S SNR NK LAKLLRF YS S KSGD e L TSL DD Y VS RMK EG Q K HIYYI T G ESKE EVE N SPF L ERL KK KGYEVLYL TDPI DE 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 572 Y CISA L P EFDGKK FQ NVAKEG FQ L N E S E KS KK NF E S LK ST FEPL V KWL N DV a L K D QIS K AQ VS E RL SN SPC A LV AGVF GW 651
Cdd:pfam00183 319 Y AVQQ L K EFDGKK LV NVAKEG LE L E E D E EE KK KD E E LK KE FEPL T KWL K DV - L G D KVE K VV VS N RL VD SPC V LV TSQY GW 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 652 TG NMER LAMSN A HQ K sd D PQRTY Y LNQ KKTLEINPRHP LMR ELL R RVEAD EA D D TAKD M A VMMFR TA T LRSG YM L QETSQ 731
Cdd:pfam00183 398 SA NMER IMKAQ A LR K -- D SSMSS Y MSS KKTLEINPRHP IIK ELL K RVEAD KD D K TAKD L A LLLYE TA L LRSG FS L EDPAS 475
490
....*....|....*..
gi 21357739 732 FA DS I EQ M MRQT LG VSQ 748
Cdd:pfam00183 476 FA SR I YR M LKLG LG IDE 492
HATPase_Hsp90-like
cd16927 Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ...
82-275
2.83e-102
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain]
Cd Length: 189
Bit Score: 312.92
E-value: 2.83e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 82 N RMMK LII N SLY R NKEIFLRELISNASDA I DK I R L L A L SNSKE L ETN PEL H IRI KA DKEN KA L H I M D S GIGMT HQD LINN 161
Cdd:cd16927 1 N QLLD LII H SLY S NKEIFLRELISNASDA L DK L R Y L S L TDPSL L DDD PEL E IRI SP DKEN RT L T I S D T GIGMT KEE LINN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 162 LGTIA K SGT AD FL AKM Q dpsks EG LDMN D M IGQFGVGFYSAF L VAD R V V VTTK HN - DD KQ Y I WESD AN - S FS I T E DPRG d 239
Cdd:cd16927 81 LGTIA R SGT KA FL EAL Q ----- EG AKDS D L IGQFGVGFYSAF M VAD K V T VTTK SA g DD EG Y R WESD GG g S YT I E E AEGE - 154
170 180 190
....*....|....*....|....*....|....*.
gi 21357739 240 t L K RG SV I S L Y LKE E A QD FLEE DTVR EL IR KYS Q FI 275
Cdd:cd16927 155 - L G RG TK I T L H LKE D A KE FLEE ARIK EL VK KYS D FI 189
Name
Accession
Description
Interval
E-value
HSP90
pfam00183 Hsp90 protein;
257-748
0e+00
Hsp90 protein;
Pssm-ID: 459703
Cd Length: 516
Bit Score: 777.89
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 257 DF LEE DTVR EL IR KYS Q FINFPI RM W SS K TV E E EVP V EEE AKP E K s E DDV ED E D A KVEE AED E -- K P KTKKV SK T T W D W T 334
Cdd:pfam00183 1 EY LEE KKIK EL VK KYS E FINFPI YL W VE K EE E V EVP D EEE EEE E E - E EEE ED D D P KVEE EDE E ee K K KTKKV KE T V W E W E 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 335 L I N DS KPIWTR K P A EVTE D EY TS FYKSL T KD SSE PL TQT HF IA EGEV T FKSLL YV PK VQ P SES F NRY g T K SD NIKLYVRR 414
Cdd:pfam00183 80 L L N KT KPIWTR N P K EVTE E EY AE FYKSL S KD WED PL AVK HF SV EGEV E FKSLL FI PK RA P FDL F ENK - K K KN NIKLYVRR 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 415 VFITD E F N D MM P N YL S F IR GVVDSDDLPLNVSRETLQQ H K LI KVIKKKLVRK V LDM L K K I -- D KE A Y E KFWKEF ST N I KL 492
Cdd:pfam00183 159 VFITD D F E D LI P E YL N F VK GVVDSDDLPLNVSRETLQQ N K IL KVIKKKLVRK A LDM F K E I ae E KE D Y K KFWKEF GK N L KL 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 493 G VM ED P SNR SR LAKLLRF QT S NGKG - V TSL AE Y KE RMK AK Q E HIYYI A G ANRA EVE K SPF V ERL LS KGYEVLYL VEAV DE 571
Cdd:pfam00183 239 G II ED S SNR NK LAKLLRF YS S KSGD e L TSL DD Y VS RMK EG Q K HIYYI T G ESKE EVE N SPF L ERL KK KGYEVLYL TDPI DE 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 572 Y CISA L P EFDGKK FQ NVAKEG FQ L N E S E KS KK NF E S LK ST FEPL V KWL N DV a L K D QIS K AQ VS E RL SN SPC A LV AGVF GW 651
Cdd:pfam00183 319 Y AVQQ L K EFDGKK LV NVAKEG LE L E E D E EE KK KD E E LK KE FEPL T KWL K DV - L G D KVE K VV VS N RL VD SPC V LV TSQY GW 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 652 TG NMER LAMSN A HQ K sd D PQRTY Y LNQ KKTLEINPRHP LMR ELL R RVEAD EA D D TAKD M A VMMFR TA T LRSG YM L QETSQ 731
Cdd:pfam00183 398 SA NMER IMKAQ A LR K -- D SSMSS Y MSS KKTLEINPRHP IIK ELL K RVEAD KD D K TAKD L A LLLYE TA L LRSG FS L EDPAS 475
490
....*....|....*..
gi 21357739 732 FA DS I EQ M MRQT LG VSQ 748
Cdd:pfam00183 476 FA SR I YR M LKLG LG IDE 492
HtpG
COG0326 Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ...
71-745
0e+00
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain]
Cd Length: 616
Bit Score: 690.32
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 71 KAKKFT FQ T EV NRMMK L I I N SLY R NKEIFLRELISNASDAIDK I R L LAL SNSKEL E TNPE L H IRI KA DKE N K A L H I M D S G 150
Cdd:COG0326 2 AKETGE FQ A EV KQLLD L M I H SLY S NKEIFLRELISNASDAIDK L R F LAL TDPELK E EDGD L K IRI EV DKE A K T L T I S D N G 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 151 IGMT HQDL I N NLGTIAKSGT AD FL A K MQDPS K SE gldm N D M IGQFGVGFYSAF L VAD R V V V T T KH -- N D DKQYI WESD AN 228
Cdd:COG0326 82 IGMT REEV I E NLGTIAKSGT RE FL E K LKGDQ K KD ---- S D L IGQFGVGFYSAF M VAD K V E V V T RS ag E D AEAVR WESD GD 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 229 - SFS I T E DPR gdt LK RG SV I S L Y LKE E A QD FLEE DTV RE L I R KYS Q FI NF PI R M wssktveeevpveeeakpekseddv E 307
Cdd:COG0326 158 g EYT I E E AEK --- AE RG TE I T L H LKE D A EE FLEE WRL RE I I K KYS D FI PV PI K M ------------------------- E 209
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 308 D E DAKV EE aedekpktkkvskttwd WTL IN DSKPI WTR KPA E V T ED EY TS FYK S L TK D SSE PL TQT H FIA EG EVTFKS LL 387
Cdd:COG0326 210 G E EEET EE ----------------- DET IN SATAL WTR SKS E I T DE EY KE FYK H L FH D FED PL FWI H LNV EG PFEYTG LL 272
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 388 Y V PK VQ P SESFN R YGTKS dn IKLYV R RVFI T D EFN D MM P N YL S F I RGVVDS D DLPLNVSRE T LQ QHKLI K V I K K KLVR KV 467
Cdd:COG0326 273 Y I PK KA P FDLYD R DRKGG -- IKLYV K RVFI M D DAE D LL P E YL R F V RGVVDS P DLPLNVSRE I LQ EDRQL K K I R K AITK KV 350
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 468 LD M L K K I --- D K E A YEKFWKEF STNI K L G VM ED PS NR SRL A K LLRF QTSNGK G VTS LAEY K ERMK AK Q EH IYYI A G AN R A 544
Cdd:COG0326 351 LD E L E K L akn D R E K YEKFWKEF GLVL K E G AL ED FK NR EKI A D LLRF ESTKEG G YVT LAEY V ERMK EG Q KK IYYI T G ES R E 430
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 545 EV E K SP FV E RLLS KG Y EVL Y L VEAV DE YC IS A L P EFDGKKF QN V AKEGFQ L NES E K s KK NF E SLKST F E PL VKWLND v AL 624
Cdd:COG0326 431 AA E Q SP HL E IFKA KG I EVL L L TDPI DE FL IS H L E EFDGKKF KS V DSGDLD L DKL E E - KK ES E EEEEE F K PL LERFKE - AL 508
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 625 K D QISKAQ VS E RL SN SP CA LVA GVFGWTGN ME RL a MSNAH Q KSDDP qrtyylnq K KT LEINP R HPL MRE L L rrve A D E AD 704
Cdd:COG0326 509 G D KVKDVR VS A RL TD SP AC LVA DEGDMSRR ME KM - LKAMG Q DMPEA -------- K PI LEINP N HPL VKK L A ---- A E E DE 575
650 660 670 680
....*....|....*....|....*....|....*....|.
gi 21357739 705 DTA KD M A VMMFRT A T L RS G YM L QETSQ F ADSIEQMMRQT LG 745
Cdd:COG0326 576 ELF KD L A ELLYDQ A L L AE G GL L EDPAA F VKRLNKLLEKA LG 616
PRK05218
PRK05218 heat shock protein 90; Provisional
74-745
0e+00
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain]
Cd Length: 613
Bit Score: 683.76
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 74 KFT FQ T EV NRMMK L I I N SLY R NKEIFLRELISNASDAIDK I R LL AL SNSKEL E TNPE L H IRI KA DKE NKA L H I M D S GIGM 153
Cdd:PRK05218 5 TGE FQ A EV KQLLH L M I H SLY S NKEIFLRELISNASDAIDK L R FE AL TDPALY E GDGD L K IRI SF DKE ART L T I S D N GIGM 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 154 T HQDL I N NLGTIAKSGT AD FL A K MQDPS K SE gldm NDM IGQFGVGFYSAF L VAD R V V V T T KH -- NDDKQYI WESD - ANSF 230
Cdd:PRK05218 85 T REEV I E NLGTIAKSGT KE FL E K LKGDQ K KD ---- SQL IGQFGVGFYSAF M VAD K V T V I T RS ag PAAEAVR WESD g EGEY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 231 S I T E DPRGD tlk RG SV I S L Y LKE EAQD FL E E DTV R EL I R KYS Q FI NF PI RM wssktveeevpveeeakpekseddveded 310
Cdd:PRK05218 161 T I E E IEKEE --- RG TE I T L H LKE DEDE FL D E WRI R SI I K KYS D FI PV PI KL ----------------------------- 208
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 311 akv E EA E D E K pktkkvskttwdwtl IN DSKPI WTR KPA E V T ED EY TS FYK S L TK D SSE PL TQT H FIA EG EVTFKS LLY V P 390
Cdd:PRK05218 209 --- E KE E E E T --------------- IN SASAL WTR SKS E I T DE EY KE FYK H L AH D FDD PL FWI H NNV EG PFEYTG LLY I P 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 391 K VQ P SES FNR ygtks D N --- I KLYV R RVFI T D EFNDMM P N YL S F IR GV V DS D DLPLNVSRE T LQ QHKLI K V I K K KLVR KV 467
Cdd:PRK05218 271 K KA P FDL FNR ----- D R kgg L KLYV K RVFI M D DAEELL P E YL R F VK GV I DS E DLPLNVSRE I LQ EDRVV K K I R K AITK KV 345
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 468 LD M L K K I --- D K E A YEKFWKEF STNI K L G VM ED PS NR SR LAKLLRF QTSNGKGVT SLAEY K ERMK AK Q EH IYYI A G AN R A 544
Cdd:PRK05218 346 LD E L E K L akn D R E K YEKFWKEF GPVL K E G LY ED FA NR EK LAKLLRF ASTHEGKYV SLAEY V ERMK EG Q KK IYYI T G DS R E 425
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 545 EVEK SP FV E RLLS KG Y EVL Y L VEAV DE YC IS A L P EFDGK K F QN VA KEGFQ L - N E S E KS K KNF E SLKST F E PL VKW L ND v A 623
Cdd:PRK05218 426 AAKN SP HL E LFKK KG I EVL L L TDPI DE FW IS Y L E EFDGK P F KS VA RGDLD L g K E D E EE K EEK E EAEEE F K PL LER L KE - A 504
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 624 L K D QISKAQV S E RL SN SP CA LVA GVFGWTGN ME R L a MSN A H Q KSDDP qrtyylnq K KT LEINP R HPL MRE L L rrve ADEA 703
Cdd:PRK05218 505 L G D KVKDVRL S H RL TD SP AC LVA DEGDMSTQ ME K L - LKA A G Q EVPES -------- K PI LEINP N HPL VKK L A ---- DEAD 571
650 660 670 680
....*....|....*....|....*....|....*....|..
gi 21357739 704 DDTA KD M A VMMFRT A T L RS G YM L QETSQ F ADSIEQMMRQT L G 745
Cdd:PRK05218 572 EAKF KD L A ELLYDQ A L L AE G GS L EDPAA F VKRLNELLLKL L A 613
HATPase_Hsp90-like
cd16927 Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ...
82-275
2.83e-102
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain]
Cd Length: 189
Bit Score: 312.92
E-value: 2.83e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 82 N RMMK LII N SLY R NKEIFLRELISNASDA I DK I R L L A L SNSKE L ETN PEL H IRI KA DKEN KA L H I M D S GIGMT HQD LINN 161
Cdd:cd16927 1 N QLLD LII H SLY S NKEIFLRELISNASDA L DK L R Y L S L TDPSL L DDD PEL E IRI SP DKEN RT L T I S D T GIGMT KEE LINN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 162 LGTIA K SGT AD FL AKM Q dpsks EG LDMN D M IGQFGVGFYSAF L VAD R V V VTTK HN - DD KQ Y I WESD AN - S FS I T E DPRG d 239
Cdd:cd16927 81 LGTIA R SGT KA FL EAL Q ----- EG AKDS D L IGQFGVGFYSAF M VAD K V T VTTK SA g DD EG Y R WESD GG g S YT I E E AEGE - 154
170 180 190
....*....|....*....|....*....|....*.
gi 21357739 240 t L K RG SV I S L Y LKE E A QD FLEE DTVR EL IR KYS Q FI 275
Cdd:cd16927 155 - L G RG TK I T L H LKE D A KE FLEE ARIK EL VK KYS D FI 189
HATPase_c
smart00387 Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
95-212
2.70e-06
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain]
Cd Length: 111
Bit Score: 46.87
E-value: 2.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 95 NKEIF LR ELI SN A sdaidkirlla L S N S - K ELETNPELHIRIKA D KENKALHIM D S G I G M thqdlinnlgtiaksg TADF 173
Cdd:smart00387 1 GDPDR LR QVL SN L ----------- L D N A i K YTPEGGRITVTLER D GDHVEITVE D N G P G I ---------------- PPED 53
90 100 110
....*....|....*....|....*....|....*....
gi 21357739 174 L A K MQD P SKSEG l DMNDM IG QF G V G FYSAFLVADRVVVT 212
Cdd:smart00387 54 L E K IFE P FFRTD - KRSRK IG GT G L G LSIVKKLVELHGGE 91
HATPase_c_3
pfam13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, ...
97-218
3.50e-03
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433332 [Multi-domain]
Cd Length: 135
Bit Score: 38.47
E-value: 3.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 97 E IF L R ELI S N AS DA I dkirll A LSNSK E LET N PELHIR I K adkenkalh I M D S G I GM THQD LIN N L G t I A K S gtadfl AK 176
Cdd:pfam13589 2 E GA L A ELI D N SI DA D ------ A TNIKI E VNK N RGGGTE I V --------- I E D D G H GM SPEE LIN A L R - L A T S ------ AK 59
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 21357739 177 MQDPSK segldmn DMI G QF G V G FYS A F L VADR - VV VT T K HNDD 218
Cdd:pfam13589 60 EAKRGS ------- TDL G RY G I G LKL A S L SLGA k LT VT S K KEGK 95
Name
Accession
Description
Interval
E-value
HSP90
pfam00183 Hsp90 protein;
257-748
0e+00
Hsp90 protein;
Pssm-ID: 459703
Cd Length: 516
Bit Score: 777.89
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 257 DF LEE DTVR EL IR KYS Q FINFPI RM W SS K TV E E EVP V EEE AKP E K s E DDV ED E D A KVEE AED E -- K P KTKKV SK T T W D W T 334
Cdd:pfam00183 1 EY LEE KKIK EL VK KYS E FINFPI YL W VE K EE E V EVP D EEE EEE E E - E EEE ED D D P KVEE EDE E ee K K KTKKV KE T V W E W E 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 335 L I N DS KPIWTR K P A EVTE D EY TS FYKSL T KD SSE PL TQT HF IA EGEV T FKSLL YV PK VQ P SES F NRY g T K SD NIKLYVRR 414
Cdd:pfam00183 80 L L N KT KPIWTR N P K EVTE E EY AE FYKSL S KD WED PL AVK HF SV EGEV E FKSLL FI PK RA P FDL F ENK - K K KN NIKLYVRR 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 415 VFITD E F N D MM P N YL S F IR GVVDSDDLPLNVSRETLQQ H K LI KVIKKKLVRK V LDM L K K I -- D KE A Y E KFWKEF ST N I KL 492
Cdd:pfam00183 159 VFITD D F E D LI P E YL N F VK GVVDSDDLPLNVSRETLQQ N K IL KVIKKKLVRK A LDM F K E I ae E KE D Y K KFWKEF GK N L KL 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 493 G VM ED P SNR SR LAKLLRF QT S NGKG - V TSL AE Y KE RMK AK Q E HIYYI A G ANRA EVE K SPF V ERL LS KGYEVLYL VEAV DE 571
Cdd:pfam00183 239 G II ED S SNR NK LAKLLRF YS S KSGD e L TSL DD Y VS RMK EG Q K HIYYI T G ESKE EVE N SPF L ERL KK KGYEVLYL TDPI DE 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 572 Y CISA L P EFDGKK FQ NVAKEG FQ L N E S E KS KK NF E S LK ST FEPL V KWL N DV a L K D QIS K AQ VS E RL SN SPC A LV AGVF GW 651
Cdd:pfam00183 319 Y AVQQ L K EFDGKK LV NVAKEG LE L E E D E EE KK KD E E LK KE FEPL T KWL K DV - L G D KVE K VV VS N RL VD SPC V LV TSQY GW 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 652 TG NMER LAMSN A HQ K sd D PQRTY Y LNQ KKTLEINPRHP LMR ELL R RVEAD EA D D TAKD M A VMMFR TA T LRSG YM L QETSQ 731
Cdd:pfam00183 398 SA NMER IMKAQ A LR K -- D SSMSS Y MSS KKTLEINPRHP IIK ELL K RVEAD KD D K TAKD L A LLLYE TA L LRSG FS L EDPAS 475
490
....*....|....*..
gi 21357739 732 FA DS I EQ M MRQT LG VSQ 748
Cdd:pfam00183 476 FA SR I YR M LKLG LG IDE 492
HtpG
COG0326 Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ...
71-745
0e+00
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain]
Cd Length: 616
Bit Score: 690.32
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 71 KAKKFT FQ T EV NRMMK L I I N SLY R NKEIFLRELISNASDAIDK I R L LAL SNSKEL E TNPE L H IRI KA DKE N K A L H I M D S G 150
Cdd:COG0326 2 AKETGE FQ A EV KQLLD L M I H SLY S NKEIFLRELISNASDAIDK L R F LAL TDPELK E EDGD L K IRI EV DKE A K T L T I S D N G 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 151 IGMT HQDL I N NLGTIAKSGT AD FL A K MQDPS K SE gldm N D M IGQFGVGFYSAF L VAD R V V V T T KH -- N D DKQYI WESD AN 228
Cdd:COG0326 82 IGMT REEV I E NLGTIAKSGT RE FL E K LKGDQ K KD ---- S D L IGQFGVGFYSAF M VAD K V E V V T RS ag E D AEAVR WESD GD 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 229 - SFS I T E DPR gdt LK RG SV I S L Y LKE E A QD FLEE DTV RE L I R KYS Q FI NF PI R M wssktveeevpveeeakpekseddv E 307
Cdd:COG0326 158 g EYT I E E AEK --- AE RG TE I T L H LKE D A EE FLEE WRL RE I I K KYS D FI PV PI K M ------------------------- E 209
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 308 D E DAKV EE aedekpktkkvskttwd WTL IN DSKPI WTR KPA E V T ED EY TS FYK S L TK D SSE PL TQT H FIA EG EVTFKS LL 387
Cdd:COG0326 210 G E EEET EE ----------------- DET IN SATAL WTR SKS E I T DE EY KE FYK H L FH D FED PL FWI H LNV EG PFEYTG LL 272
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 388 Y V PK VQ P SESFN R YGTKS dn IKLYV R RVFI T D EFN D MM P N YL S F I RGVVDS D DLPLNVSRE T LQ QHKLI K V I K K KLVR KV 467
Cdd:COG0326 273 Y I PK KA P FDLYD R DRKGG -- IKLYV K RVFI M D DAE D LL P E YL R F V RGVVDS P DLPLNVSRE I LQ EDRQL K K I R K AITK KV 350
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 468 LD M L K K I --- D K E A YEKFWKEF STNI K L G VM ED PS NR SRL A K LLRF QTSNGK G VTS LAEY K ERMK AK Q EH IYYI A G AN R A 544
Cdd:COG0326 351 LD E L E K L akn D R E K YEKFWKEF GLVL K E G AL ED FK NR EKI A D LLRF ESTKEG G YVT LAEY V ERMK EG Q KK IYYI T G ES R E 430
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 545 EV E K SP FV E RLLS KG Y EVL Y L VEAV DE YC IS A L P EFDGKKF QN V AKEGFQ L NES E K s KK NF E SLKST F E PL VKWLND v AL 624
Cdd:COG0326 431 AA E Q SP HL E IFKA KG I EVL L L TDPI DE FL IS H L E EFDGKKF KS V DSGDLD L DKL E E - KK ES E EEEEE F K PL LERFKE - AL 508
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 625 K D QISKAQ VS E RL SN SP CA LVA GVFGWTGN ME RL a MSNAH Q KSDDP qrtyylnq K KT LEINP R HPL MRE L L rrve A D E AD 704
Cdd:COG0326 509 G D KVKDVR VS A RL TD SP AC LVA DEGDMSRR ME KM - LKAMG Q DMPEA -------- K PI LEINP N HPL VKK L A ---- A E E DE 575
650 660 670 680
....*....|....*....|....*....|....*....|.
gi 21357739 705 DTA KD M A VMMFRT A T L RS G YM L QETSQ F ADSIEQMMRQT LG 745
Cdd:COG0326 576 ELF KD L A ELLYDQ A L L AE G GL L EDPAA F VKRLNKLLEKA LG 616
PRK05218
PRK05218 heat shock protein 90; Provisional
74-745
0e+00
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain]
Cd Length: 613
Bit Score: 683.76
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 74 KFT FQ T EV NRMMK L I I N SLY R NKEIFLRELISNASDAIDK I R LL AL SNSKEL E TNPE L H IRI KA DKE NKA L H I M D S GIGM 153
Cdd:PRK05218 5 TGE FQ A EV KQLLH L M I H SLY S NKEIFLRELISNASDAIDK L R FE AL TDPALY E GDGD L K IRI SF DKE ART L T I S D N GIGM 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 154 T HQDL I N NLGTIAKSGT AD FL A K MQDPS K SE gldm NDM IGQFGVGFYSAF L VAD R V V V T T KH -- NDDKQYI WESD - ANSF 230
Cdd:PRK05218 85 T REEV I E NLGTIAKSGT KE FL E K LKGDQ K KD ---- SQL IGQFGVGFYSAF M VAD K V T V I T RS ag PAAEAVR WESD g EGEY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 231 S I T E DPRGD tlk RG SV I S L Y LKE EAQD FL E E DTV R EL I R KYS Q FI NF PI RM wssktveeevpveeeakpekseddveded 310
Cdd:PRK05218 161 T I E E IEKEE --- RG TE I T L H LKE DEDE FL D E WRI R SI I K KYS D FI PV PI KL ----------------------------- 208
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 311 akv E EA E D E K pktkkvskttwdwtl IN DSKPI WTR KPA E V T ED EY TS FYK S L TK D SSE PL TQT H FIA EG EVTFKS LLY V P 390
Cdd:PRK05218 209 --- E KE E E E T --------------- IN SASAL WTR SKS E I T DE EY KE FYK H L AH D FDD PL FWI H NNV EG PFEYTG LLY I P 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 391 K VQ P SES FNR ygtks D N --- I KLYV R RVFI T D EFNDMM P N YL S F IR GV V DS D DLPLNVSRE T LQ QHKLI K V I K K KLVR KV 467
Cdd:PRK05218 271 K KA P FDL FNR ----- D R kgg L KLYV K RVFI M D DAEELL P E YL R F VK GV I DS E DLPLNVSRE I LQ EDRVV K K I R K AITK KV 345
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 468 LD M L K K I --- D K E A YEKFWKEF STNI K L G VM ED PS NR SR LAKLLRF QTSNGKGVT SLAEY K ERMK AK Q EH IYYI A G AN R A 544
Cdd:PRK05218 346 LD E L E K L akn D R E K YEKFWKEF GPVL K E G LY ED FA NR EK LAKLLRF ASTHEGKYV SLAEY V ERMK EG Q KK IYYI T G DS R E 425
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 545 EVEK SP FV E RLLS KG Y EVL Y L VEAV DE YC IS A L P EFDGK K F QN VA KEGFQ L - N E S E KS K KNF E SLKST F E PL VKW L ND v A 623
Cdd:PRK05218 426 AAKN SP HL E LFKK KG I EVL L L TDPI DE FW IS Y L E EFDGK P F KS VA RGDLD L g K E D E EE K EEK E EAEEE F K PL LER L KE - A 504
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 624 L K D QISKAQV S E RL SN SP CA LVA GVFGWTGN ME R L a MSN A H Q KSDDP qrtyylnq K KT LEINP R HPL MRE L L rrve ADEA 703
Cdd:PRK05218 505 L G D KVKDVRL S H RL TD SP AC LVA DEGDMSTQ ME K L - LKA A G Q EVPES -------- K PI LEINP N HPL VKK L A ---- DEAD 571
650 660 670 680
....*....|....*....|....*....|....*....|..
gi 21357739 704 DDTA KD M A VMMFRT A T L RS G YM L QETSQ F ADSIEQMMRQT L G 745
Cdd:PRK05218 572 EAKF KD L A ELLYDQ A L L AE G GS L EDPAA F VKRLNELLLKL L A 613
PTZ00272
PTZ00272 heat shock protein 83 kDa (Hsp83); Provisional
75-747
0e+00
heat shock protein 83 kDa (Hsp83); Provisional
Pssm-ID: 240341
Cd Length: 701
Bit Score: 639.42
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 75 F T FQ T E V N RM M K LIIN SL Y R NKEIFLRELISNASDA I DKIR LLA L SNSKE L ETN P E L H IR IKA DKENK A L HIM D S GIGMT 154
Cdd:PTZ00272 5 F A FQ A E I N QL M S LIIN TF Y S NKEIFLRELISNASDA C DKIR YQS L TDPSV L GES P R L C IR VVP DKENK T L TVE D N GIGMT 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 155 HQ DL I NNLGTIA K SGT AD F LAKMQ dpsks E G L DM N d MIGQFGVGFYSA F LVADRV V VT T K H N D D KQ Y I WES D A - NS F S IT 233
Cdd:PTZ00272 85 KA DL V NNLGTIA R SGT KA F MEALE ----- A G G DM S - MIGQFGVGFYSA Y LVADRV T VT S K N N S D ES Y V WES S A g GT F T IT 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 234 ED P RG D t L KRG SV I S L Y LKE EAQDF LE EDTVR ELI R K Y S Q FI NFP I RMWSS KT V E E EV PV E E E AKPE K SED dv ED E DA KV 313
Cdd:PTZ00272 159 ST P ES D - M KRG TR I T L H LKE DQMEY LE PRRLK ELI K K H S E FI GYD I ELMVE KT T E K EV TD E D E EDTK K ADE -- DG E EP KV 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 314 EE ---- A E DE K P KTKKV SKT T WDWTLI N DS KP I WTR K P AE VT ED EY TS FYK SLTK D SSE P LTQT HF IA EG EVT F K S LLY V 389
Cdd:PTZ00272 236 EE vkeg D E GK K K KTKKV KEV T KEYEVQ N KH KP L WTR D P KD VT KE EY AA FYK AISN D WED P AATK HF SV EG QLE F R S IMF V 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 390 PK VQ P SES F NR y GT K SD NIKLYVRRVFI T D EFN D MM P NY L S F IR GVVDS D DLPLN V SRE T LQQ H K LI KVI K K KL V R K V L D 469
Cdd:PTZ00272 316 PK RA P FDM F EP - NK K RN NIKLYVRRVFI M D NCE D LC P DW L G F VK GVVDS E DLPLN I SRE N LQQ N K IL KVI R K NI V K K C L E 394
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 470 M LKKI -- D KE A Y EK F WKE F ST NIKLG VM ED PS NR SR L AK LLRF QTS - N G KGV T S L AE Y KE RMKA K Q EH IYYI A G ANRAEV 546
Cdd:PTZ00272 395 M FDEV ae N KE D Y KQ F YEQ F GK NIKLG IH ED TA NR KK L ME LLRF YST e S G EEM T T L KD Y VT RMKA G Q KS IYYI T G DSKKKL 474
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 547 E K SPF V E RLLSK G Y EVL YLV E AV DEY CISALPE F DG KKF QNVA KEG FQLN ESE KS K KNF E SL K STF E P L V K WLND V a L K D 626
Cdd:PTZ00272 475 E T SPF I E QARRR G L EVL FMT E PI DEY VMQQVKD F ED KKF ACLT KEG VHFE ESE EE K QQR E EE K AAC E K L C K TMKE V - L G D 553
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 627 QIS K AQ VSERLS N SPC A LV AGV FGW TGN ME RL a M S N ah Q KSD D PQRTY Y LNQ KKT L E I NPRHP LMR EL L RRV E ADE A D DT 706
Cdd:PTZ00272 554 KVE K VI VSERLS T SPC I LV TSE FGW SAH ME QI - M R N -- Q ALR D SSMAQ Y MMS KKT M E L NPRHP IIK EL R RRV G ADE N D KA 630
650 660 670 680
....*....|....*....|....*....|....*....|.
gi 21357739 707 A KD MAVMM F R T AT L R SG YM L QETSQF A DS I EQ M MR qt LG V S 747
Cdd:PTZ00272 631 V KD LVFLL F D T SL L T SG FQ L EDPTGY A ER I NR M IK -- LG L S 669
PTZ00130
PTZ00130 heat shock protein 90; Provisional
49-746
0e+00
heat shock protein 90; Provisional
Pssm-ID: 185466 [Multi-domain]
Cd Length: 814
Bit Score: 546.18
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 49 K R E E E AIQL D GL N VAQLKEIR --- EKAKKFTF QTEV N R M M KL I I NSLY RN KE I FLRELISNA S DA ID KIR L L A LS NSKE L 125
Cdd:PTZ00130 39 K E E K E EVKK D RD N IPEIEDGE kpt SGIEQHQY QTEV T R L M DI I V NSLY TQ KE V FLRELISNA A DA LE KIR F L S LS DESV L 118
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 126 ETNPE L H IRI K A D KE NKA L H I M D S GIGMT HQ DLINNLGTIAKSGT AD FL AKM qdp SKS E G l DM N d M IGQFGVGFYSAFLV 205
Cdd:PTZ00130 119 GEEKK L E IRI S A N KE KNI L S I T D T GIGMT KE DLINNLGTIAKSGT SN FL EAI --- SKS G G - DM S - L IGQFGVGFYSAFLV 193
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 206 AD R V V V T TK H N D D K QYIWES D A NS - F S I TE DPRG D TLKRG SV ISL Y LKE E A QDFLEEDTVRE LI R KYSQFI NF PI RMWSS 284
Cdd:PTZ00130 194 AD K V I V Y TK N N N D E QYIWES T A DA k F T I YK DPRG S TLKRG TR ISL H LKE D A TNLMNDKKLVD LI S KYSQFI QY PI YLLHE 273
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 285 KTVE EEV PVEEE akp EKS E D D VEDEDA KVEE AE D EKP KT KK V S K TTWD W T L I N DS KPIW T R K P A E V T EDE Y TS F YKS L TK 364
Cdd:PTZ00130 274 NVYT EEV LADIA --- KEM E N D PNYDSV KVEE TD D PNK KT RT V E K KVKK W K L M N EQ KPIW L R P P K E L T DED Y KK F FSV L SG 350
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 365 DSS EPL TQT HF I AEGE VT FK S L L Y V P KVQ PS ESFNRY g TK SDN IKLYVRRV FIT DEF NDMM P N Y L SF IR GVVDSDDLPLN 444
Cdd:PTZ00130 351 FND EPL YHI HF F AEGE IE FK C L I Y I P SRA PS INDHLF - TK QNS IKLYVRRV LVA DEF VEFL P R Y M SF VK GVVDSDDLPLN 429
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 445 VSRE T LQQ H K LI K VIK K KL VRK V LD MLKKID KE A -------------------------------- Y EKFW KE FSTNI K L 492
Cdd:PTZ00130 430 VSRE Q LQQ N K IL K AVS K RI VRK I LD TFRTLY KE G kknketlraelaketdeekkkeiqkkinepst Y KLIY KE YRKYL K T 509
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 493 G VM ED PS NR SRLA KLL R F Q T SNGKGVT SL AE Y K E R MK AK Q EH IYY IA G ANRAEVE K S P FVERLLS K GYE V LY L V E A VDE Y 572
Cdd:PTZ00130 510 G CY ED DI NR NKIV KLL L F K T MLHPKSI SL DT Y I E N MK PD Q KF IYY AS G DSYEYLS K I P QLQIFKK K NID V VF L T E S VDE S 589
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 573 C ISALP E F DGKKF QNVA K EGFQLNES E KS KK NF E SL K STFEP L VKWLN D v A L KD QI S K AQV S E RL SNS PCA L V AGVF G WT 652
Cdd:PTZ00130 590 C VQRVQ E Y DGKKF KSIQ K GEITFELT E DE KK KE E KV K KMYKA L IDVIS D - T L RN QI F K VEI S R RL VDA PCA V V STEW G LS 668
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 653 G N ME R L AMS N A hqks DDPQRTYYLNQK K T LEINP R HP L M RE LL R R VEADEA D DTAKDMAVMMFRT A T L R SG YM L QE T SQF 732
Cdd:PTZ00130 669 G Q ME K L MKI N V ---- NNSDQIKAMSGQ K I LEINP D HP I M ID LL K R SVSNPK D SQLTESIKIIYQS A K L A SG FD L ED T ADL 744
730
....*....|....
gi 21357739 733 A DSIEQMMR Q T LGV 746
Cdd:PTZ00130 745 A QIVYDHIN Q K LGV 758
HATPase_Hsp90-like
cd16927 Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ...
82-275
2.83e-102
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain]
Cd Length: 189
Bit Score: 312.92
E-value: 2.83e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 82 N RMMK LII N SLY R NKEIFLRELISNASDA I DK I R L L A L SNSKE L ETN PEL H IRI KA DKEN KA L H I M D S GIGMT HQD LINN 161
Cdd:cd16927 1 N QLLD LII H SLY S NKEIFLRELISNASDA L DK L R Y L S L TDPSL L DDD PEL E IRI SP DKEN RT L T I S D T GIGMT KEE LINN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 162 LGTIA K SGT AD FL AKM Q dpsks EG LDMN D M IGQFGVGFYSAF L VAD R V V VTTK HN - DD KQ Y I WESD AN - S FS I T E DPRG d 239
Cdd:cd16927 81 LGTIA R SGT KA FL EAL Q ----- EG AKDS D L IGQFGVGFYSAF M VAD K V T VTTK SA g DD EG Y R WESD GG g S YT I E E AEGE - 154
170 180 190
....*....|....*....|....*....|....*.
gi 21357739 240 t L K RG SV I S L Y LKE E A QD FLEE DTVR EL IR KYS Q FI 275
Cdd:cd16927 155 - L G RG TK I T L H LKE D A KE FLEE ARIK EL VK KYS D FI 189
PRK14083
PRK14083 HSP90 family protein; Provisional
76-527
6.72e-33
HSP90 family protein; Provisional
Pssm-ID: 237603 [Multi-domain]
Cd Length: 601
Bit Score: 135.07
E-value: 6.72e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 76 T FQ TEVNRMMK L IINS LY RNKEIFL REL IS NA S DAI DKI R L L alsnsk ELETNPELH I RI k A D KENKA L HIM D S GIG M T H 155
Cdd:PRK14083 4 R FQ VDLRGVID L LSRH LY SSPRVYV REL LQ NA V DAI TAR R A L ------ DPTAPGRIR I EL - T D AGGGT L IVE D N GIG L T E 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 156 QDLINN L G TI AK S gtadflakmqdp SK SE --- G LDM ND MI GQFG V G FY S A FLVAD RV VV TTKHND D KQYI - W ESD A N - SF 230
Cdd:PRK14083 77 EEVHEF L A TI GR S ------------ SK RD enl G FAR ND FL GQFG I G LL S C FLVAD EI VV VSRSAK D GPAV e W RGK A D g TY 144
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 231 S ITEDP r GDTLKR G SVIS L YLKEE A QDF LE ED TV R EL IR KY SQFINF PIR mwssktveeevpveeeakpeksedd VE D E D 310
Cdd:PRK14083 145 S VRKLE - TERAEP G TTVY L RPRPD A EEW LE RE TV E EL AK KY GSLLPV PIR ------------------------- VE G E K 198
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 311 akveeaedekpktkkvskttwdw TLI N DSK P I WTR KPAEVTEDE ----------- YTSFYKSLTK D S se P LTQTHFI A eg 379
Cdd:PRK14083 199 ----------------------- GGV N ETP P P WTR DYPDPETRR eallaygeell GFTPLDVIPL D V -- P SGGLEGV A -- 251
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 380 evtfksll YV - P - K V Q P SES f NRY gtksdni KL Y VR R VFITD E FNDMM P NYLS F I R G VV DS D D L PLNV SRE T L QQHKLIK 457
Cdd:PRK14083 252 -------- YV l P y A V S P AAR - RKH ------- RV Y LK R MLLSE E AENLL P DWAF F V R C VV NT D E L RPTA SRE A L YEDDALA 315
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 21357739 458 VIKK --- KLV RK V L DM L KKI D K E AYEKFWKEFSTNI K - L GVME D PSN R S r LAKL L R F Q T SN gk G VTS LAE YKE R 527
Cdd:PRK14083 316 AVRE elg EAI RK W L IG L ATT D P E RLRRLLAVHHLGV K a L ASHD D ELL R L - ILPW L P F E T TD -- G RMT LAE IRR R 386
HATPase_c
smart00387 Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
95-212
2.70e-06
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain]
Cd Length: 111
Bit Score: 46.87
E-value: 2.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 95 NKEIF LR ELI SN A sdaidkirlla L S N S - K ELETNPELHIRIKA D KENKALHIM D S G I G M thqdlinnlgtiaksg TADF 173
Cdd:smart00387 1 GDPDR LR QVL SN L ----------- L D N A i K YTPEGGRITVTLER D GDHVEITVE D N G P G I ---------------- PPED 53
90 100 110
....*....|....*....|....*....|....*....
gi 21357739 174 L A K MQD P SKSEG l DMNDM IG QF G V G FYSAFLVADRVVVT 212
Cdd:smart00387 54 L E K IFE P FFRTD - KRSRK IG GT G L G LSIVKKLVELHGGE 91
HATPase_c_3
pfam13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, ...
97-218
3.50e-03
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433332 [Multi-domain]
Cd Length: 135
Bit Score: 38.47
E-value: 3.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21357739 97 E IF L R ELI S N AS DA I dkirll A LSNSK E LET N PELHIR I K adkenkalh I M D S G I GM THQD LIN N L G t I A K S gtadfl AK 176
Cdd:pfam13589 2 E GA L A ELI D N SI DA D ------ A TNIKI E VNK N RGGGTE I V --------- I E D D G H GM SPEE LIN A L R - L A T S ------ AK 59
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 21357739 177 MQDPSK segldmn DMI G QF G V G FYS A F L VADR - VV VT T K HNDD 218
Cdd:pfam13589 60 EAKRGS ------- TDL G RY G I G LKL A S L SLGA k LT VT S K KEGK 95
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
