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Conserved domains on  [gi|21358561|ref|NP_651737|]
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dim gamma-tubulin 1, isoform A [Drosophila melanogaster]

Protein Classification

zf-C3Hc3H domain-containing protein( domain architecture ID 10620855)

zf-C3Hc3H domain-containing protein may be a DNA-binding protein and is similar to human KAT8 regulatory NSL complex subunit 2 that, as part of the NSL complex, is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 354-411 1.15e-15

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


:

Pssm-ID: 464023  Cd Length: 62  Bit Score: 71.23  E-value: 1.15e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358561   354 GGVKCGERTLPCCKHCRKHILEDKRQVLFRACGVERSG-VVCQEPVASILEDSS-CVLHL 411
Cdd:pfam13891   3 YGVGCKQKALPGTKYCYRHILEDPNQALFKQCSYVFSGnKRCGNPVLKSDVPSPlCPEHA 62
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 42-108 2.31e-14

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


:

Pssm-ID: 464023  Cd Length: 62  Bit Score: 67.37  E-value: 2.31e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 21358561    42 CANpTYECSLMRIEGYEYCIRHILRDPRSN-FRQCSHVYSNGRKCINAVAKYDNKKeliltTLCFEHN 108
Cdd:pfam13891   1 CSY-GVGCKQKALPGTKYCYRHILEDPNQAlFKQCSYVFSGNKRCGNPVLKSDVPS-----PLCPEHA 62
 
Name Accession Description Interval E-value
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 354-411 1.15e-15

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


Pssm-ID: 464023  Cd Length: 62  Bit Score: 71.23  E-value: 1.15e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358561   354 GGVKCGERTLPCCKHCRKHILEDKRQVLFRACGVERSG-VVCQEPVASILEDSS-CVLHL 411
Cdd:pfam13891   3 YGVGCKQKALPGTKYCYRHILEDPNQALFKQCSYVFSGnKRCGNPVLKSDVPSPlCPEHA 62
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 42-108 2.31e-14

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


Pssm-ID: 464023  Cd Length: 62  Bit Score: 67.37  E-value: 2.31e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 21358561    42 CANpTYECSLMRIEGYEYCIRHILRDPRSN-FRQCSHVYSNGRKCINAVAKYDNKKeliltTLCFEHN 108
Cdd:pfam13891   1 CSY-GVGCKQKALPGTKYCYRHILEDPNQAlFKQCSYVFSGNKRCGNPVLKSDVPS-----PLCPEHA 62
 
Name Accession Description Interval E-value
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 354-411 1.15e-15

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


Pssm-ID: 464023  Cd Length: 62  Bit Score: 71.23  E-value: 1.15e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358561   354 GGVKCGERTLPCCKHCRKHILEDKRQVLFRACGVERSG-VVCQEPVASILEDSS-CVLHL 411
Cdd:pfam13891   3 YGVGCKQKALPGTKYCYRHILEDPNQALFKQCSYVFSGnKRCGNPVLKSDVPSPlCPEHA 62
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 42-108 2.31e-14

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


Pssm-ID: 464023  Cd Length: 62  Bit Score: 67.37  E-value: 2.31e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 21358561    42 CANpTYECSLMRIEGYEYCIRHILRDPRSN-FRQCSHVYSNGRKCINAVAKYDNKKeliltTLCFEHN 108
Cdd:pfam13891   1 CSY-GVGCKQKALPGTKYCYRHILEDPNQAlFKQCSYVFSGNKRCGNPVLKSDVPS-----PLCPEHA 62
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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