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Conserved domains on  [gi|24646017|ref|NP_652712|]
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uncharacterized protein Dmel_CG18764 [Drosophila melanogaster]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 10657792)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940|30718982
SCOP:  4003583

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-AD smart00868
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 4-75 2.30e-09

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


:

Pssm-ID: 214871  Cd Length: 73  Bit Score: 53.67  E-value: 2.30e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24646017      4 QCRTCGSIIYNKMPknLFHIENEKML-QDINLVTGTTLHNDPELPSSICACCTLDLNQAILFRERCILTQKQL 75
Cdd:smart00868   1 VCRLCLSESENLVS--IFDESSEASLaEKIEECTGIEIEPDDGLPKVICGDCLEKLESFHKFRERCRESDELL 71
zf-H2C2_2 pfam13465
Zinc-finger double domain;
272-297 3.44e-03

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 3.44e-03
                          10        20
                  ....*....|....*....|....*.
gi 24646017   272 NFKLHMLRHTGNKNFACQQCGKRFYT 297
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
333-354 6.45e-03

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 6.45e-03
                          10        20
                  ....*....|....*....|..
gi 24646017   333 HERTHTNAKPYSCHHCDKCFKS 354
Cdd:pfam13465   5 HMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
zf-AD smart00868
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 4-75 2.30e-09

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 214871  Cd Length: 73  Bit Score: 53.67  E-value: 2.30e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24646017      4 QCRTCGSIIYNKMPknLFHIENEKML-QDINLVTGTTLHNDPELPSSICACCTLDLNQAILFRERCILTQKQL 75
Cdd:smart00868   1 VCRLCLSESENLVS--IFDESSEASLaEKIEECTGIEIEPDDGLPKVICGDCLEKLESFHKFRERCRESDELL 71
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 4-75 3.52e-06

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 462262  Cd Length: 75  Bit Score: 44.37  E-value: 3.52e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24646017     4 QCRTCGSIIYNKMPKNLFHIENEKMLQDINLVTGTTLHNDPELPSSICACCTLDLNQAILFRERCILTQKQL 75
Cdd:pfam07776   1 VCRLCLDESDELIPIFDPSDSEKTLAEILEDCTGIELDPNDLLPKQICERCLSKLQEFYSFRERCLESQELL 72
zf-H2C2_2 pfam13465
Zinc-finger double domain;
272-297 3.44e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 3.44e-03
                          10        20
                  ....*....|....*....|....*.
gi 24646017   272 NFKLHMLRHTGNKNFACQQCGKRFYT 297
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
333-354 6.45e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 6.45e-03
                          10        20
                  ....*....|....*....|..
gi 24646017   333 HERTHTNAKPYSCHHCDKCFKS 354
Cdd:pfam13465   5 HMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
zf-AD smart00868
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 4-75 2.30e-09

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 214871  Cd Length: 73  Bit Score: 53.67  E-value: 2.30e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24646017      4 QCRTCGSIIYNKMPknLFHIENEKML-QDINLVTGTTLHNDPELPSSICACCTLDLNQAILFRERCILTQKQL 75
Cdd:smart00868   1 VCRLCLSESENLVS--IFDESSEASLaEKIEECTGIEIEPDDGLPKVICGDCLEKLESFHKFRERCRESDELL 71
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 4-75 3.52e-06

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 462262  Cd Length: 75  Bit Score: 44.37  E-value: 3.52e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24646017     4 QCRTCGSIIYNKMPKNLFHIENEKMLQDINLVTGTTLHNDPELPSSICACCTLDLNQAILFRERCILTQKQL 75
Cdd:pfam07776   1 VCRLCLDESDELIPIFDPSDSEKTLAEILEDCTGIELDPNDLLPKQICERCLSKLQEFYSFRERCLESQELL 72
zf-H2C2_2 pfam13465
Zinc-finger double domain;
272-297 3.44e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 3.44e-03
                          10        20
                  ....*....|....*....|....*.
gi 24646017   272 NFKLHMLRHTGNKNFACQQCGKRFYT 297
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
333-354 6.45e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 6.45e-03
                          10        20
                  ....*....|....*....|..
gi 24646017   333 HERTHTNAKPYSCHHCDKCFKS 354
Cdd:pfam13465   5 HMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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