leucine-rich repeat protein 1 isoform 1 [Homo sapiens]
leucine-rich repeat domain-containing protein( domain architecture ID 11469232)
leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions
List of domain hits
Name | Accession | Description | Interval | E-value | |||
LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
176-316 | 2.57e-27 | |||
Leucine-rich repeat (LRR) protein [Transcription]; : Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 112.33 E-value: 2.57e-27
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Name | Accession | Description | Interval | E-value | ||||
LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
176-316 | 2.57e-27 | ||||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 112.33 E-value: 2.57e-27
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PPP1R42 | cd21340 | protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
175-304 | 4.80e-07 | ||||
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation. Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 50.17 E-value: 4.80e-07
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LRR_8 | pfam13855 | Leucine rich repeat; |
178-238 | 8.72e-07 | ||||
Leucine rich repeat; Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.98 E-value: 8.72e-07
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PRK15370 | PRK15370 | type III secretion system effector E3 ubiquitin transferase SlrP; |
178-337 | 2.17e-06 | ||||
type III secretion system effector E3 ubiquitin transferase SlrP; Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 50.08 E-value: 2.17e-06
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Name | Accession | Description | Interval | E-value | ||||
LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
176-316 | 2.57e-27 | ||||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 112.33 E-value: 2.57e-27
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LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
155-304 | 2.03e-26 | ||||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 110.02 E-value: 2.03e-26
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LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
176-325 | 3.83e-26 | ||||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 109.25 E-value: 3.83e-26
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LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
192-304 | 6.50e-15 | ||||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 76.13 E-value: 6.50e-15
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LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
176-332 | 7.19e-10 | ||||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 60.33 E-value: 7.19e-10
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PPP1R42 | cd21340 | protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
175-304 | 4.80e-07 | ||||
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation. Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 50.17 E-value: 4.80e-07
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LRR_8 | pfam13855 | Leucine rich repeat; |
178-238 | 8.72e-07 | ||||
Leucine rich repeat; Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.98 E-value: 8.72e-07
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RNA1 | COG5238 | Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
177-285 | 1.65e-06 | ||||
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis]; Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 49.79 E-value: 1.65e-06
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PRK15370 | PRK15370 | type III secretion system effector E3 ubiquitin transferase SlrP; |
178-337 | 2.17e-06 | ||||
type III secretion system effector E3 ubiquitin transferase SlrP; Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 50.08 E-value: 2.17e-06
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PLN00113 | PLN00113 | leucine-rich repeat receptor-like protein kinase; Provisional |
178-318 | 8.71e-06 | ||||
leucine-rich repeat receptor-like protein kinase; Provisional Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 47.92 E-value: 8.71e-06
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PLN00113 | PLN00113 | leucine-rich repeat receptor-like protein kinase; Provisional |
182-304 | 1.19e-05 | ||||
leucine-rich repeat receptor-like protein kinase; Provisional Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 47.54 E-value: 1.19e-05
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LRR_RI | cd00116 | Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
176-261 | 1.55e-05 | ||||
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1). Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 46.58 E-value: 1.55e-05
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PLN00113 | PLN00113 | leucine-rich repeat receptor-like protein kinase; Provisional |
182-306 | 1.90e-05 | ||||
leucine-rich repeat receptor-like protein kinase; Provisional Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 47.15 E-value: 1.90e-05
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PRK15370 | PRK15370 | type III secretion system effector E3 ubiquitin transferase SlrP; |
157-288 | 2.97e-05 | ||||
type III secretion system effector E3 ubiquitin transferase SlrP; Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 46.23 E-value: 2.97e-05
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PLN00113 | PLN00113 | leucine-rich repeat receptor-like protein kinase; Provisional |
177-261 | 5.66e-05 | ||||
leucine-rich repeat receptor-like protein kinase; Provisional Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 45.61 E-value: 5.66e-05
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PRK15387 | PRK15387 | type III secretion system effector E3 ubiquitin transferase SspH2; |
179-313 | 7.44e-05 | ||||
type III secretion system effector E3 ubiquitin transferase SspH2; Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 45.15 E-value: 7.44e-05
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PLN03150 | PLN03150 | hypothetical protein; Provisional |
192-261 | 9.30e-05 | ||||
hypothetical protein; Provisional Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 44.81 E-value: 9.30e-05
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PPP1R42 | cd21340 | protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
177-242 | 1.35e-04 | ||||
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation. Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 42.85 E-value: 1.35e-04
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LRR_8 | pfam13855 | Leucine rich repeat; |
201-261 | 1.36e-04 | ||||
Leucine rich repeat; Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.43 E-value: 1.36e-04
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LRR_8 | pfam13855 | Leucine rich repeat; |
176-212 | 3.48e-04 | ||||
Leucine rich repeat; Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 38.27 E-value: 3.48e-04
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LRR_4 | pfam12799 | Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
177-212 | 5.56e-04 | ||||
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains. Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 37.22 E-value: 5.56e-04
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PLN03150 | PLN03150 | hypothetical protein; Provisional |
178-212 | 1.35e-03 | ||||
hypothetical protein; Provisional Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 40.95 E-value: 1.35e-03
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LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
202-308 | 2.46e-03 | ||||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 39.92 E-value: 2.46e-03
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LRR_RI | cd00116 | Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
155-240 | 5.99e-03 | ||||
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1). Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 38.49 E-value: 5.99e-03
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Blast search parameters | ||||
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