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Conserved domains on  [gi|222537714|ref|NP_694967|]
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beta-taxilin [Homo sapiens]

Protein Classification

taxilin( domain architecture ID 12101238)

taxilin is a myosin-like coiled-coil protein involved in intracellular vesicle traffic

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Taxilin pfam09728
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ...
 143-450 1.65e-105

Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.


:

Pssm-ID: 462861 [Multi-domain]  Cd Length: 302  Bit Score: 322.67  E-value: 1.65e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  143 KEANLLMQNLNKLQTPEEKFDFLFKKYAELLDEHRTEQKKLKLLQKKQVQIQKEKDQLQGEHSRAILARSKLESLCRELQ 222
Cdd:pfam09728   1 KAARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQKDLKKLKKKQDQLQKEKDQLQSELSKAILAKSKLEKLCRELQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  223 RHNKTLKEEALQRAREEEEKRKEITSHFQSTLTDIQGQIEQQSERNMKLCQENTELAEKLKSIIDQYELREEHLDKIFKH 302
Cdd:pfam09728  81 KQNKKLKEESKKLAKEEEEKRKELSEKFQSTLKDIQDKMEEKSEKNNKLREENEELREKLKSLIEQYELRELHFEKLLKT 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  303 RELQQKLVDAKLEQAQemmkEAEERHKREKEYllNQAAEWKLQAKVLKEQETVLQAQLTLYSGRFEEFQSTLTKSNEVFA 382
Cdd:pfam09728 161 KELEVQLAEAKLQQAT----EEEEKKAQEKEV--AKARELKAQVQTLSETEKELREQLNLYVEKFEEFQDTLNKSNEVFT 234

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 222537714  383 TFKQEMDKTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYECFVMKIGRLENLCRALQEE 450
Cdd:pfam09728 235 TFKKEMEKMSKKIKKLEKENLTWKRKWEKSNKALLEMAEERQKLKEELEKLQKKLEKLENLCRALQAE 302
PRK12323 super family cl46901
DNA polymerase III subunit gamma/tau;
519-683 6.73e-06

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK12323:

Pssm-ID: 481241 [Multi-domain]  Cd Length: 700  Bit Score: 49.49  E-value: 6.73e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 519 QSKETQPEIGSSQESADAALKEPEQPPLIPSRDSESPLPPLTPQAEAEGGSDAEPPSKASNSPAGLGAETQCEGLPVGAQ 598
Cdd:PRK12323 368 SGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGA 447

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 599 ADQASWKPEAEASGQAPQAPteASLQKMEADVPAPACAAEEHVAAMVP-ACEPSRQPPRAAAEELPVGASAGPQPRNVAD 677
Cdd:PRK12323 448 PAPAPAPAAAPAAAARPAAA--GPRPVAAAAAAAPARAAPAAAPAPADdDPPPWEELPPEFASPAPAQPDAAPAGWVAES 525


                 ....*.
gi 222537714 678 TNLEGV 683
Cdd:PRK12323 526 IPDPAT 531
 
Name Accession Description Interval E-value
Taxilin pfam09728
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ...
 143-450 1.65e-105

Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.


Pssm-ID: 462861 [Multi-domain]  Cd Length: 302  Bit Score: 322.67  E-value: 1.65e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  143 KEANLLMQNLNKLQTPEEKFDFLFKKYAELLDEHRTEQKKLKLLQKKQVQIQKEKDQLQGEHSRAILARSKLESLCRELQ 222
Cdd:pfam09728   1 KAARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQKDLKKLKKKQDQLQKEKDQLQSELSKAILAKSKLEKLCRELQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  223 RHNKTLKEEALQRAREEEEKRKEITSHFQSTLTDIQGQIEQQSERNMKLCQENTELAEKLKSIIDQYELREEHLDKIFKH 302
Cdd:pfam09728  81 KQNKKLKEESKKLAKEEEEKRKELSEKFQSTLKDIQDKMEEKSEKNNKLREENEELREKLKSLIEQYELRELHFEKLLKT 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  303 RELQQKLVDAKLEQAQemmkEAEERHKREKEYllNQAAEWKLQAKVLKEQETVLQAQLTLYSGRFEEFQSTLTKSNEVFA 382
Cdd:pfam09728 161 KELEVQLAEAKLQQAT----EEEEKKAQEKEV--AKARELKAQVQTLSETEKELREQLNLYVEKFEEFQDTLNKSNEVFT 234

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 222537714  383 TFKQEMDKTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYECFVMKIGRLENLCRALQEE 450
Cdd:pfam09728 235 TFKKEMEKMSKKIKKLEKENLTWKRKWEKSNKALLEMAEERQKLKEELEKLQKKLEKLENLCRALQAE 302
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 213-456 2.04e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 2.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714   213 KLESLCRELQRHNKTLKEEALQRAREEEEKRKEITSHFQS------TLTDIQGQIEQQSERNMKLCQENTELAEKLKSII 286
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQisalrkDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714   287 DQYELREEHLDKIFKHRELQQKLVDAKLEQAQ---EMMKEAEERHKREK----------EYLLNQAAEWKLQAKVLKEQE 353
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKalrEALDELRAELTLLNeeaanlrerlESLERRIAATERRLEDLEEQI 847

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714   354 TVLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMDKTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYECF 433
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927

                          250       260
                   ....*....|....*....|...
gi 222537714   434 VMKIGRLENLCRALQEERNELHK 456
Cdd:TIGR02168  928 ELRLEGLEVRIDNLQERLSEEYS 950
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
519-683 6.73e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 49.49  E-value: 6.73e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 519 QSKETQPEIGSSQESADAALKEPEQPPLIPSRDSESPLPPLTPQAEAEGGSDAEPPSKASNSPAGLGAETQCEGLPVGAQ 598
Cdd:PRK12323 368 SGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGA 447

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 599 ADQASWKPEAEASGQAPQAPteASLQKMEADVPAPACAAEEHVAAMVP-ACEPSRQPPRAAAEELPVGASAGPQPRNVAD 677
Cdd:PRK12323 448 PAPAPAPAAAPAAAARPAAA--GPRPVAAAAAAAPARAAPAAAPAPADdDPPPWEELPPEFASPAPAQPDAAPAGWVAES 525


                 ....*.
gi 222537714 678 TNLEGV 683
Cdd:PRK12323 526 IPDPAT 531
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 192-477 6.20e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.00  E-value: 6.20e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 192 QIQKEKDQLQgehsrAILARSKLESLCRELQRHNKTLKEEALQRAReeeekrkeitshFQSTLTDIQGQIEQQSERNMKL 271
Cdd:COG1196  217 ELKEELKELE-----AELLLLKLRELEAELEELEAELEELEAELEE------------LEAELAELEAELEELRLELEEL 279

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 272 CQENTELAEKLKSIIDqyelREEHLDKIFKHRELQQKLVDAKLEQAQEMMKEAEERHKREKEyllnQAAEWKLQAKVLKE 351
Cdd:COG1196  280 ELELEEAQAEEYELLA----ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE----ELEELEEELEEAEE 351

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 352 QETVLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMDKTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYE 431
Cdd:COG1196  352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 222537714 432 CFVMKIGRLENLCRALQEERNELHKKIRDAEISEKDDQSQHNSDEE 477
Cdd:COG1196  432 ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477
 
Name Accession Description Interval E-value
Taxilin pfam09728
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ...
 143-450 1.65e-105

Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.


Pssm-ID: 462861 [Multi-domain]  Cd Length: 302  Bit Score: 322.67  E-value: 1.65e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  143 KEANLLMQNLNKLQTPEEKFDFLFKKYAELLDEHRTEQKKLKLLQKKQVQIQKEKDQLQGEHSRAILARSKLESLCRELQ 222
Cdd:pfam09728   1 KAARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQKDLKKLKKKQDQLQKEKDQLQSELSKAILAKSKLEKLCRELQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  223 RHNKTLKEEALQRAREEEEKRKEITSHFQSTLTDIQGQIEQQSERNMKLCQENTELAEKLKSIIDQYELREEHLDKIFKH 302
Cdd:pfam09728  81 KQNKKLKEESKKLAKEEEEKRKELSEKFQSTLKDIQDKMEEKSEKNNKLREENEELREKLKSLIEQYELRELHFEKLLKT 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  303 RELQQKLVDAKLEQAQemmkEAEERHKREKEYllNQAAEWKLQAKVLKEQETVLQAQLTLYSGRFEEFQSTLTKSNEVFA 382
Cdd:pfam09728 161 KELEVQLAEAKLQQAT----EEEEKKAQEKEV--AKARELKAQVQTLSETEKELREQLNLYVEKFEEFQDTLNKSNEVFT 234

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 222537714  383 TFKQEMDKTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYECFVMKIGRLENLCRALQEE 450
Cdd:pfam09728 235 TFKKEMEKMSKKIKKLEKENLTWKRKWEKSNKALLEMAEERQKLKEELEKLQKKLEKLENLCRALQAE 302
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 213-456 2.04e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 2.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714   213 KLESLCRELQRHNKTLKEEALQRAREEEEKRKEITSHFQS------TLTDIQGQIEQQSERNMKLCQENTELAEKLKSII 286
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQisalrkDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714   287 DQYELREEHLDKIFKHRELQQKLVDAKLEQAQ---EMMKEAEERHKREK----------EYLLNQAAEWKLQAKVLKEQE 353
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKalrEALDELRAELTLLNeeaanlrerlESLERRIAATERRLEDLEEQI 847

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714   354 TVLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMDKTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYECF 433
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927

                          250       260
                   ....*....|....*....|...
gi 222537714   434 VMKIGRLENLCRALQEERNELHK 456
Cdd:TIGR02168  928 ELRLEGLEVRIDNLQERLSEEYS 950
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
519-683 6.73e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 49.49  E-value: 6.73e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 519 QSKETQPEIGSSQESADAALKEPEQPPLIPSRDSESPLPPLTPQAEAEGGSDAEPPSKASNSPAGLGAETQCEGLPVGAQ 598
Cdd:PRK12323 368 SGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGA 447

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 599 ADQASWKPEAEASGQAPQAPteASLQKMEADVPAPACAAEEHVAAMVP-ACEPSRQPPRAAAEELPVGASAGPQPRNVAD 677
Cdd:PRK12323 448 PAPAPAPAAAPAAAARPAAA--GPRPVAAAAAAAPARAAPAAAPAPADdDPPPWEELPPEFASPAPAQPDAAPAGWVAES 525


                 ....*.
gi 222537714 678 TNLEGV 683
Cdd:PRK12323 526 IPDPAT 531
PHA03247 PHA03247
large tegument protein UL36; Provisional
 545-677 1.54e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.78  E-value: 1.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  545 PLIPSRDSESPLPPLTPQAEAEGGSDAEPPSKASNSPAGLGAETQCEGLPVGAQADQASWkPEAEASGQAPQAPTEASLQ 624
Cdd:PHA03247 2673 AAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQAS-PALPAAPAPPAVPAGPATP 2751

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 222537714  625 KMEADVPAPACAA--EEHVAAMVPACEPSRQPPRAAAEELPVGASAGPQPRNVAD 677
Cdd:PHA03247 2752 GGPARPARPPTTAgpPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPAD 2806
PHA03247 PHA03247
large tegument protein UL36; Provisional
 525-672 2.29e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 2.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  525 PEIGSSQESADAALKEPEQPPLIPSRDSESPLPPLTpqAEAEGGSDAEP----PSKASNSPAGLGAETQcEGLPVGAQAD 600
Cdd:PHA03247 2690 PTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGP--AAARQASPALPaapaPPAVPAGPATPGGPAR-PARPPTTAGP 2766

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 222537714  601 QASWKPEAEASGQAPQAPTEASLQKMEADVPAPACAAEEHVAAMVPACEPSRQPPRAAAEELPVGASAGPQP 672
Cdd:PHA03247 2767 PAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTA 2838
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 512-672 3.10e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 47.29  E-value: 3.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 512 HPESTPHQSKETQPEIGSSQESADAALKEPEQPPLIPSRDSESPLPPLTPqAEAEGGSDAEPPSKASNSPAGLGAETQCE 591
Cdd:PRK07764 600 PPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAA-PEHHPKHVAVPDASDGGDGWPAKAGGAAP 678

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 592 GLPVGAQADQASWKPEAEASGQ-APQAPTEASLQKMEADVPAPACAAEEhvAAMVPACEPSRQPPRAAAEELPVGASAGP 670
Cdd:PRK07764 679 AAPPPAPAPAAPAAPAGAAPAQpAPAPAATPPAGQADDPAAQPPQAAQG--ASAPSPAADDPVPLPPEPDDPPDPAGAPA 756


                 ..
gi 222537714 671 QP 672
Cdd:PRK07764 757 QP 758
PHA03247 PHA03247
large tegument protein UL36; Provisional
 513-676 8.40e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.08  E-value: 8.40e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  513 PESTPHQSKETQPEIGSSQESADAALKEPEQP--------PLIPSRDSESPLPPLT--PQAEAEGGSDAEPPSKASNSPA 582
Cdd:PHA03247 2708 PEPAPHALVSATPLPPGPAAARQASPALPAAPappavpagPATPGGPARPARPPTTagPPAPAPPAAPAAGPPRRLTRPA 2787

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  583 GLGAETQCEGLP-------VGAQADQASWKPEAEASGQAPQAPTEASLQKMEADVPAPACAAEEHVAAMVPACEPSRQPP 655
Cdd:PHA03247 2788 VASLSESRESLPspwdpadPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPP 2867

                         170       180
                  ....*....|....*....|.
gi 222537714  656 RAAAEELPvGASAGPQPRNVA 676
Cdd:PHA03247 2868 SRSPAAKP-AAPARPPVRRLA 2887
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 194-465 2.60e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.28  E-value: 2.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714   194 QKEKDQLQGEHSRAILARskLESLCRELQRHNKTLKEEAlQRAREEEEKRKEITS-HFQSTLTDIQGQIEQQSERNMKLC 272
Cdd:TIGR02168  173 RRKETERKLERTRENLDR--LEDILNELERQLKSLERQA-EKAERYKELKAELRElELALLVLRLEELREELEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714   273 QENTELaEKLKSIIDQYElrEEHLDKIFKHRELQQKLVDA------------KLEQAQEMMKEAEERHKREKEYLLNQAA 340
Cdd:TIGR02168  250 EAEEEL-EELTAELQELE--EKLEELRLEVSELEEEIEELqkelyalaneisRLEQQKQILRERLANLERQLEELEAQLE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714   341 EWKLQAKVLKEQETVLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMDkttkkmkklekdtaTWKARFENCNKALLDMI 420
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLE--------------ELEEQLETLRSKVAQLE 392

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 222537714   421 EEKALRAKEYECFVMKIGRLENLCRALQEERNELHKKIRDAEISE 465
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKE 437
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 548-683 3.36e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 3.36e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 548 PSRDSESPLPPLTPQAEAEGGSDAEPPSKASNSPAGLGAETQCEGLPVGAQADQASWKPEAEASGQAPQAPTEAslqkme 627
Cdd:PRK07764 398 APSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPA------ 471

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 222537714 628 ADVPAPACAAEEHVAAMVPACEPsRQPPRAAAeelPVGASAGPQPRNVADTNLEGV 683
Cdd:PRK07764 472 AAPEPTAAPAPAPPAAPAPAAAP-AAPAAPAA---PAGADDAATLRERWPEILAAV 523
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 192-477 6.20e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.00  E-value: 6.20e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 192 QIQKEKDQLQgehsrAILARSKLESLCRELQRHNKTLKEEALQRAReeeekrkeitshFQSTLTDIQGQIEQQSERNMKL 271
Cdd:COG1196  217 ELKEELKELE-----AELLLLKLRELEAELEELEAELEELEAELEE------------LEAELAELEAELEELRLELEEL 279

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 272 CQENTELAEKLKSIIDqyelREEHLDKIFKHRELQQKLVDAKLEQAQEMMKEAEERHKREKEyllnQAAEWKLQAKVLKE 351
Cdd:COG1196  280 ELELEEAQAEEYELLA----ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE----ELEELEEELEEAEE 351

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 352 QETVLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMDKTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYE 431
Cdd:COG1196  352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 222537714 432 CFVMKIGRLENLCRALQEERNELHKKIRDAEISEKDDQSQHNSDEE 477
Cdd:COG1196  432 ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 46-474 8.44e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 42.65  E-value: 8.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714    46 EKEASVHPDISEELNRQLEDIINTYGSAASTAGKEGSARASEQPENAESPDNEDGDCEETTEEAGREPVASGEPPTVKE- 124
Cdd:pfam02463  622 AKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEi 701

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714   125 --PVSNKEQKLEKKILKGLGKEANLLMQNLNKLQTPEEKFDFLFKKYAELLDEHRTEQKKLKLLQKKQVQIQKeKDQLQG 202
Cdd:pfam02463  702 kkKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEK-ELAEER 780

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714   203 EHSRAILARSKLESLCRELQRHNKTLKEEALQRAREEEEKRKEITshfqstltdiQGQIEQQSERNMKLCQENTELAEKL 282
Cdd:pfam02463  781 EKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIE----------QEEKIKEEELEELALELKEEQKLEK 850

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714   283 KSIIDQYELREEHLDKIFKHRELQQKLVDAKLEQAQEMMKEAEERHKREKEYLLNQAAEWKLQAKVLKEQETVLQAQLTL 362
Cdd:pfam02463  851 LAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEIL 930

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714   363 YSGRFEEFQSTLTKSNEVFATFKQEMDKTTKKMKKlekdtatwKARFENCNKALLDMIEEKALRAKEYECFVMKIGRLEN 442
Cdd:pfam02463  931 LKYEEEPEELLLEEADEKEKEENNKEEEEERNKRL--------LLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEE 1002

                          410       420       430
                   ....*....|....*....|....*....|..
gi 222537714   443 LCRALQEERNELHKKIRDAEISEKDDQSQHNS 474
Cdd:pfam02463 1003 EKKKLIRAIIEETCQRLKEFLELFVSINKGWN 1034
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
525-673 9.14e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.53  E-value: 9.14e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 525 PEIGSSQESADAALKEPEQPPLipsrdSESPLPPLTPQAEAEGGSDAEPPSKASNSPAGLGAETQCEGL-PVGAQADQAS 603
Cdd:PRK07003 381 PAPGARAAAAVGASAVPAVTAV-----TGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADgDAPVPAKANA 455

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 222537714 604 WKPEAEASGQAPQAPTEASLQKMEADVPAPACAAEE------HVAAMVPACEPSRQPPRAAAEELPVGASAGPQPR 673
Cdd:PRK07003 456 RASADSRCDERDAQPPADSGSASAPASDAPPDAAFEpapraaAPSAATPAAVPDARAPAAASREDAPAAAAPPAPE 531
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
531-668 1.22e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.14  E-value: 1.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 531 QESADAALKEPEQPPLIPSRDSESPLPPLTPQAEAEGGSDAEPPSKASNSPAGLGAETQCEGLPVGAQADQASWKPEAEA 610
Cdd:PRK07003 413 KAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEP 492

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 222537714 611 SGQAPQAPTEASLQKMEADVPAPACAAEEHVAAMVPACEPSRQPPRAAAEELPVGASA 668
Cdd:PRK07003 493 APRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAA 550
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 121-371 1.55e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 1.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714   121 TVKEPVSNKEQKLEKKILKGLGKEANL------LMQNLNKLQTPEEKFDFLFKKYAELLDEHRTEQKKLKLLQKKQVQIQ 194
Cdd:TIGR02168  702 ELRKELEELEEELEQLRKELEELSRQIsalrkdLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE 781

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714   195 KEKDQLQGEHSRAILARSKLESLCRELQRHNKTLKEEALQRAREEEEKRKEITShFQSTLTDIQGQIEQQSER------N 268
Cdd:TIGR02168  782 AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAA-TERRLEDLEEQIEELSEDieslaaE 860

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714   269 MKLCQEN-TELAEKLKSIIDQYELREEHLDKIFKHRELQQKLVDAKLEQAQEMMKEAEE-RHKREKEYLLNQAAEWK--- 343
Cdd:TIGR02168  861 IEELEELiEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEElREKLAQLELRLEGLEVRidn 940

                          250       260
                   ....*....|....*....|....*...
gi 222537714   344 LQAKVLKEQETVLQAQLTLYSGRFEEFQ 371
Cdd:TIGR02168  941 LQERLSEEYSLTLEEAEALENKIEDDEE 968
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 535-684 1.71e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.51  E-value: 1.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 535 DAALKEPEQPPLIPSRDSESPLPPLTPQAEAEGGSDAEPPSKASNSPAGLGAETQCEGLPVGAQADQASWKPEAEASGQA 614
Cdd:PRK07764 591 APGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWP 670

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 615 PQAPTEASlqkmEADVPAPACAAEEHVAAMVPACEPSRQPPRAAAEElpvGASAGPQPRNVADTNLEGVD 684
Cdd:PRK07764 671 AKAGGAAP----AAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQ---ADDPAAQPPQAAQGASAPSP 733
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
534-670 1.84e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 41.76  E-value: 1.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 534 ADAALKEPEQPPLIPSRDSESPLPPLTPQAEAEGGSDAEPPSkASNSPAGLGAETQCEGLPVGAQADQASWKPEAEASGQ 613
Cdd:PRK07003 402 VTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAA-DGDAPVPAKANARASADSRCDERDAQPPADSGSASAP 480

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 222537714 614 APQAPTEASLQKMEADVPAPACAAEEHVAAMVPACEPSRQPPRAAAEELPVGASAGP 670
Cdd:PRK07003 481 ASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTP 537
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 167-481 2.53e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.08  E-value: 2.53e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 167 KKYAELLDEHRteqkkLKLLQKKQVQIQKEKDQLQGEHSRAILARSKLESLCRELQRHNKTLKEEALQRAREEEEKRKEI 246
Cdd:COG1196  213 ERYRELKEELK-----ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ 287

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 247 TSHFQ--STLTDIQGQIEQQSERNMKLCQENTELAEKLKSIIDQYELREEHLDKIfkhrELQQKLVDAKLEQAQEMMKEA 324
Cdd:COG1196  288 AEEYEllAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEEL----EEELEEAEEELEEAEAELAEA 363

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 325 EERHKREKEyllnQAAEWKLQAKVLKEQETVLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMDKTTKKMKKLEKDTAT 404
Cdd:COG1196  364 EEALLEAEA----ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 222537714 405 WKARFENCNKALLDMIEEKALRAKEYEcfvmkigrlenlcrALQEERNELHKKIRDAEISEKDDQSQHNSDEEPESN 481
Cdd:COG1196  440 EEEALEEAAEEEAELEEEEEALLELLA--------------ELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
513-655 2.92e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.99  E-value: 2.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 513 PESTPHQSKETQPEIGSSQESADAALKEPEQPPLIPSRDSESPLPPLTPQAEAEGGSDAEPPSKASNSPAGLGAeTQCEG 592
Cdd:PRK07003 482 SDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDV-LRNAG 560

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 222537714 593 LPVGA---QADQASWKPEAEASGQAPQAPTEASLQKMEADVPAPACAAEEHVAAMVPACEPSRQPP 655
Cdd:PRK07003 561 MRVSSdrgARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPPNGAARAEQAAESRGAP 626
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 522-673 4.50e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.54  E-value: 4.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  522 ETQPEIGSSQESADAALKEPEQPPLIP-----SRDSESPLPPlTPQAEAEGGSDAEPPSKASNSPAGLGAETQCEGLPVG 596
Cdd:PHA03307   68 PTGPPPGPGTEAPANESRSTPTWSLSTlapasPAREGSPTPP-GPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGP 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  597 AQADQASWKPEAEASGQAPQA-PTEAS--LQKMEADVPAPACAAEEhvaaMVPACEPSRQPPRAAAEELPVGASAG-PQP 672
Cdd:PHA03307  147 PPAASPPAAGASPAAVASDAAsSRQAAlpLSSPEETARAPSSPPAE----PPPSTPPAAASPRPPRRSSPISASASsPAP 222


                  .
gi 222537714  673 R 673
Cdd:PHA03307  223 A 223
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
515-676 4.92e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.22  E-value: 4.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 515 STPHQSKETQPEIGSSQESADAALKEPEQPPLIPsrDSESPLPPLTPQAEAEGGSDAEPPSKASNSPAGlGAETQCEGLP 594
Cdd:PRK07003 430 PAPPATADRGDDAADGDAPVPAKANARASADSRC--DERDAQPPADSGSASAPASDAPPDAAFEPAPRA-AAPSAATPAA 506

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 595 VGAQADQASWKPEAEASGQAPQAPTEASLQKMEADVPAPACAAEEHV-----AAMVPACEPSRQPPRAAAEELPVGASAG 669
Cdd:PRK07003 507 VPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALdvlrnAGMRVSSDRGARAAAAAKPAAAPAAAPK 586


                 ....*..
gi 222537714 670 PQPRNVA 676
Cdd:PRK07003 587 PAAPRVA 593
PHA03247 PHA03247
large tegument protein UL36; Provisional
 535-678 5.26e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.31  E-value: 5.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  535 DAALKEPEQPPL---------IPSRDSESPLPPLTPQAEAEGGSDAEPPSKASNSPAG--LGAETQCEGLPVGAQADQAS 603
Cdd:PHA03247 2522 DEPVGEPVHPRMltwirgleeLASDDAGDPPPPLPPAAPPAAPDRSVPPPRPAPRPSEpaVTSRARRPDAPPQSARPRAP 2601

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  604 WKPEAEASGQAPQAPTEASLQKMEADVPAPACAAEE----HVAAMVPACEPSRQPP--------RAAAEELPVGASA--- 668
Cdd:PHA03247 2602 VDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEpdphPPPTVPPPERPRDDPApgrvsrprRARRLGRAAQASSppq 2681

                         170
                  ....*....|
gi 222537714  669 GPQPRNVADT 678
Cdd:PHA03247 2682 RPRRRAARPT 2691
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
193-460 6.96e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.90  E-value: 6.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  193 IQKEKDQLQGEHSRAILARSKLESLCRELQRhnktlKEEALQRAREEEEKRKEITSHfQSTLTDIQGQIEQQSERNMKLc 272
Cdd:COG4913   615 LEAELAELEEELAEAEERLEALEAELDALQE-----RREALQRLAEYSWDEIDVASA-EREIAELEAELERLDASSDDL- 687

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  273 QENTELAEKLKSIIDqyELREEHLDKIFKHRELQQKLVDAK--LEQAQEMMKEAEERHKREKEYLLNQAAEWKLQAKVLK 350
Cdd:COG4913   688 AALEEQLEELEAELE--ELEEELDELKGEIGRLEKELEQAEeeLDELQDRLEAAEDLARLELRALLEERFAAALGDAVER 765

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  351 EQETVLQAQLTLYSGRFEEFQSTLTKsneVFATFKQEMDKTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEy 430
Cdd:COG4913   766 ELRENLEERIDALRARLNRAEEELER---AMRAFNREWPAETADLDADLESLPEYLALLDRLEEDGLPEYEERFKELLN- 841

                         250       260       270
                  ....*....|....*....|....*....|
gi 222537714  431 ecfVMKIGRLENLCRALQEERNELHKKIRD 460
Cdd:COG4913   842 ---ENSIEFVADLLSKLRRAIREIKERIDP 868
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 561-672 6.99e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 39.70  E-value: 6.99e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 561 PQAEAEGGSDAE-----PPSKASNSPAGLgAETQCEGLPVGAQADQASWKPEAEASGQAPQAPTEASLQKMEADVPAPAC 635
Cdd:PRK14951 366 PAAAAEAAAPAEkktpaRPEAAAPAAAPV-AQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAA 444

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 222537714 636 AAEEHVAAMVPACEPSRQPPRAAAEelPVGASAGPQP 672
Cdd:PRK14951 445 VALAPAPPAQAAPETVAIPVRVAPE--PAVASAAPAP 479
rne PRK10811
ribonuclease E; Reviewed
 478-656 7.42e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 39.64  E-value: 7.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  478 PESNVSVDQEIDAEEVNSVQTAVKNLATAfmiihhpestphqsketQPEIGSSQESADAALKEPEQPPLIPSRDSESPLP 557
Cdd:PRK10811  849 RPQDVQVEEQREAEEVQVQPVVAEVPVAA-----------------AVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVV 911

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714  558 PLTPQAEAEGGSDAEPPSKASNSPAGLGAETQCEGLPVGAQADQASWKPEAEASG-QAPQAPTEASLQKMEADVPAPACA 636
Cdd:PRK10811  912 VETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAeVVVAEPEVVAQPAAPVVAEVAAEV 991

                         170       180
                  ....*....|....*....|
gi 222537714  637 AEEHVAAMVPACEPSRQPPR 656
Cdd:PRK10811  992 ETVTAVEPEVAPAQVPEATV 1011
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
533-679 8.28e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 39.45  E-value: 8.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 533 SADAALKEPEQPPLIPS---RDSESPLPPLTPQAEAEGGSDAEPPSKASNSPAglgAETQCEGLPVGAQADQASWKPEAE 609
Cdd:PRK07003 366 GAPGGGVPARVAGAVPApgaRAAAAVGASAVPAVTAVTGAAGAALAPKAAAAA---AATRAEAPPAAPAPPATADRGDDA 442

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222537714 610 ASGQAPQAPTEASlqKMEADVPAPACAAEEHVAAMVPACEPSRQPPRAAAEELPVGASAGPQPRNVADTN 679
Cdd:PRK07003 443 ADGDAPVPAKANA--RASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDA 510
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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