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Conserved domains on  [gi|24654066|ref|NP_725541|]
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mrj, isoform A [Drosophila melanogaster]

Protein Classification

J domain-containing protein( domain architecture ID 1001220)

J domain-containing protein similar to molecular chaperone DnaJ, part of the DnaK-DnaJ-GrpE system, prevents the aggregation of unfolded substrate and acts primarily by stimulating the ATPase activity of Hsp70

CATH:  1.10.287.110
Gene Ontology:  GO:0006457
PubMed:  9644977|8016869|15170475
SCOP:  4000605

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DnaJ_bact super family cl37091
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 3-117 1.59e-37

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


The actual alignment was detected with superfamily member TIGR02349:

Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 135.04  E-value: 1.59e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066     3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDnlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLgDRGQSRSH 82
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKD--KEAEEKFKEINEAYEVLSDPEKRAQYDQFGHAGF-NGGGGGGG 77

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 24654066    83 ArhhysthDFDDFDILGgfqfaFRPPEEVFREFFG 117
Cdd:TIGR02349  78 G-------GFNGFDIGF-----FGDFGDIFGDFFG 100
 
Name Accession Description Interval E-value
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 3-117 1.59e-37

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 135.04  E-value: 1.59e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066     3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDnlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLgDRGQSRSH 82
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKD--KEAEEKFKEINEAYEVLSDPEKRAQYDQFGHAGF-NGGGGGGG 77

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 24654066    83 ArhhysthDFDDFDILGgfqfaFRPPEEVFREFFG 117
Cdd:TIGR02349  78 G-------GFNGFDIGF-----FGDFGDIFGDFFG 100
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 3-66 1.05e-35

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 121.43  E-value: 1.05e-35
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24654066     3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSDEKKRRIYD 66
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGD-PEAEEKFKEINEAYEVLSDPEKRAIYD 63
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 3-117 1.96e-35

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 129.88  E-value: 1.96e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRGQSRSh 82
Cdd:PRK10767   5 DYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGD-KEAEEKFKEIKEAYEVLSDPQKRAAYDQYGHAAFEQGGGGGG- 82

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 24654066   83 arhhysthdfddFDILGGFQFAFrppEEVFREFFG 117
Cdd:PRK10767  83 ------------FGGGGGFGDIF---GDIFGDIFG 102
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 3-91 3.00e-35

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 122.89  E-value: 3.00e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066   3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRGQSRSH 82
Cdd:COG0484   1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGD-PEAEEKFKEINEAYEVLSDPEKRAAYDRFGHAAELLLATELAE 79


                ....*....
gi 24654066  83 ARHHYSTHD 91
Cdd:COG0484  80 SAAAEAAAA 88
DnaJ smart00271
DnaJ molecular chaperone homology domain;
2-61 1.86e-29

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 105.39  E-value: 1.86e-29
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066      2 VDYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNLDEANKRFRELSEAYEVLSDEKK 61
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKEEAEEKFKEINEAYEVLSDPEK 60
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
3-118 8.93e-28

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 110.29  E-value: 8.93e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDnlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLgdrgqsrsh 82
Cdd:NF037946   6 DYYEVLGVDRDADDQEIKKAFRKLAKKYHPDRNKA--PDAAEIFAEINEAYEVLSNPEKRANYDKYGHDGV--------- 74

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 24654066   83 arhhysthdfddfDILGGFQFAfrpPEEVFREFFGI 118
Cdd:NF037946  75 -------------DGEGGFGFD---AFDVFSSFFET 94
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 3-58 5.49e-27

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 98.77  E-value: 5.49e-27
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 24654066   3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSD 58
Cdd:cd06257   1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDD-PEAEEKFKEINEAYEVLSD 55
 
Name Accession Description Interval E-value
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 3-117 1.59e-37

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 135.04  E-value: 1.59e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066     3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDnlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLgDRGQSRSH 82
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKD--KEAEEKFKEINEAYEVLSDPEKRAQYDQFGHAGF-NGGGGGGG 77

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 24654066    83 ArhhysthDFDDFDILGgfqfaFRPPEEVFREFFG 117
Cdd:TIGR02349  78 G-------GFNGFDIGF-----FGDFGDIFGDFFG 100
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 3-66 1.05e-35

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 121.43  E-value: 1.05e-35
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24654066     3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSDEKKRRIYD 66
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGD-PEAEEKFKEINEAYEVLSDPEKRAIYD 63
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 3-117 1.96e-35

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 129.88  E-value: 1.96e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRGQSRSh 82
Cdd:PRK10767   5 DYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGD-KEAEEKFKEIKEAYEVLSDPQKRAAYDQYGHAAFEQGGGGGG- 82

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 24654066   83 arhhysthdfddFDILGGFQFAFrppEEVFREFFG 117
Cdd:PRK10767  83 ------------FGGGGGFGDIF---GDIFGDIFG 102
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 3-91 3.00e-35

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 122.89  E-value: 3.00e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066   3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRGQSRSH 82
Cdd:COG0484   1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGD-PEAEEKFKEINEAYEVLSDPEKRAAYDRFGHAAELLLATELAE 79


                ....*....
gi 24654066  83 ARHHYSTHD 91
Cdd:COG0484  80 SAAAEAAAA 88
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 3-117 2.62e-33

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 124.11  E-value: 2.62e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRGQSRSh 82
Cdd:PRK14294   5 DYYEILGVTRDASEEEIKKSYRKLAMKYHPDRNPGD-KEAEELFKEAAEAYEVLSDPKKRGIYDQYGHEGLSGTGFSGF- 82

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 24654066   83 arhhystHDFDdfDILGGFQfafrppeEVFREFFG 117
Cdd:PRK14294  83 -------SGFD--DIFSSFG-------DIFEDFFG 101
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 3-117 2.24e-32

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 122.22  E-value: 2.24e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRGQSRSH 82
Cdd:PRK14281   4 DYYEVLGVSRSADKDEIKKAYRKLALKYHPDKNPDN-KEAEEHFKEVNEAYEVLSNDDKRRRYDQFGHAGVGSSAASGGG 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 24654066   83 ARHHYSTHDFDDF-----DILGGFQFAFRPPEEVFREFFG 117
Cdd:PRK14281  83 PGYGGGGGDFNDIfsafnDMFGGGARRGGGSPFGFEDVFG 122
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 3-126 1.70e-31

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 119.49  E-value: 1.70e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDnlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRGQsrsh 82
Cdd:PRK14291   4 DYYEILGVSRNATQEEIKKAYRRLARKYHPDFNKN--PEAEEKFKEINEAYQVLSDPEKRKLYDQFGHAAFSGSGQ---- 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 24654066   83 arhhysthDFDDFDILGGFQFAfrPPEEVFREFFGIHSpFADLF 126
Cdd:PRK14291  78 --------QQQGQEGFSDFGGG--NIEDILEDVFDIFG-FGDIF 110
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 3-117 1.42e-30

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 117.08  E-value: 1.42e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDnlDEANKRFRELSEAYEVLSDEKKRRIYDeYGKDGLGDRGQSRsh 82
Cdd:PRK14278   4 DYYGLLGVSRNASDAEIKRAYRKLARELHPDVNPD--EEAQEKFKEISVAYEVLSDPEKRRIVD-LGGDPLESAGGGG-- 78

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 24654066   83 arhhysthdfddfdilGGFQFAFRPPEEVFREFFG 117
Cdd:PRK14278  79 ----------------GGFGGGFGGLGDVFEAFFG 97
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 3-126 7.08e-30

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 115.03  E-value: 7.08e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNLDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRGQSrsh 82
Cdd:PRK14290   4 DYYKILGVDRNASQEDIKKAFRELAKKWHPDLHPGNKAEAEEKFKEISEAYEVLSDPQKRRQYDQTGTVDFGAGGSN--- 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 24654066   83 arhhYSTHDFDDFDILggfqfafrppEEVFREFFGihSPFADLF 126
Cdd:PRK14290  81 ----FNWDNFTHFSDI----------NDIFNQIFG--GNFGSDF 108
DnaJ smart00271
DnaJ molecular chaperone homology domain;
2-61 1.86e-29

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 105.39  E-value: 1.86e-29
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066      2 VDYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNLDEANKRFRELSEAYEVLSDEKK 61
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKEEAEEKFKEINEAYEVLSDPEK 60
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 3-73 4.61e-29

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 113.01  E-value: 4.61e-29
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNLdEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGL 73
Cdd:PRK14284   2 DYYTILGVSKTASPEEIKKAYRKLAVKYHPDKNPGDA-EAEKRFKEVSEAYEVLSDAQKRESYDRYGKDGP 71
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 3-117 6.82e-29

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 112.14  E-value: 6.82e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRGqsrsh 82
Cdd:PRK14301   5 DYYEVLGVSRDASEDEIKKAYRKLALQYHPDRNPDN-PEAEQKFKEAAEAYEVLRDAEKRARYDRFGHAGVNGNG----- 78

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 24654066   83 ARHHYSTHDfddfDILGGFQfafrppeEVFREFFG 117
Cdd:PRK14301  79 GFGGFSSAE----DIFSHFS-------DIFGDLFG 102
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 3-117 1.05e-28

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 112.20  E-value: 1.05e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRGQSRSH 82
Cdd:PRK14277   6 DYYEILGVDRNATEEEIKKAYRRLAKKYHPDLNPGD-KEAEQKFKEINEAYEILSDPQKRAQYDQFGHAAFDPGGFGQGG 84

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 24654066   83 ARHHYSTHDFDDFDiLGGFQFAFrppEEVFREFFG 117
Cdd:PRK14277  85 FGQGGFGGGGFDFD-FGGFGDIF---EDIFGDFFG 115
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
3-118 8.93e-28

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 110.29  E-value: 8.93e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDnlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLgdrgqsrsh 82
Cdd:NF037946   6 DYYEVLGVDRDADDQEIKKAFRKLAKKYHPDRNKA--PDAAEIFAEINEAYEVLSNPEKRANYDKYGHDGV--------- 74

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 24654066   83 arhhysthdfddfDILGGFQFAfrpPEEVFREFFGI 118
Cdd:NF037946  75 -------------DGEGGFGFD---AFDVFSSFFET 94
PRK14282 PRK14282
chaperone protein DnaJ; Provisional
 3-126 1.07e-27

chaperone protein DnaJ; Provisional


Pssm-ID: 184603 [Multi-domain]  Cd Length: 369  Bit Score: 109.11  E-value: 1.07e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNLDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRGQSRSH 82
Cdd:PRK14282   5 DYYEILGVSRNATQEEIKRAYKRLVKEWHPDRHPENRKEAEQKFKEIQEAYEVLSDPQKRAMYDRFGYVGEQPPYQETES 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 24654066   83 ARHHYST--HDFDDF---DILGGFqFAFRPPEEVFREF--------FGIHSPFADLF 126
Cdd:PRK14282  85 GGGFFEDifKDFENIfnrDIFDIF-FGERRTQEEQREYarrgedirYEIEVTLSDLI 140
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 4-117 3.99e-27

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 107.38  E-value: 3.99e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    4 YYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLgdrgqsrSHA 83
Cdd:PRK14286   6 YYDILGVSKSANDEEIKSAYRKLAIKYHPDKNKGN-KESEEKFKEATEAYEILRDPKKRQAYDQFGKAGV-------NAG 77

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 24654066   84 RHHYSTHDFDDF-DILGGFQfafrppeEVFREFFG 117
Cdd:PRK14286  78 AGGFGQGAYTDFsDIFGDFG-------DIFGDFFG 105
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 3-117 5.26e-27

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 107.24  E-value: 5.26e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDnlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRgqsrsh 82
Cdd:PRK14298   6 DYYEILGLSKDASVEDIKKAYRKLAMKYHPDKNKE--PDAEEKFKEISEAYAVLSDAEKRAQYDRFGHAGIDNQ------ 77

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 24654066   83 arhhYSTHD-FDDFDiLGGFqfafrppEEVFREFFG 117
Cdd:PRK14298  78 ----YSAEDiFRGAD-FGGF-------GDIFEMFFG 101
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 3-58 5.49e-27

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 98.77  E-value: 5.49e-27
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 24654066   3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSD 58
Cdd:cd06257   1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDD-PEAEEKFKEINEAYEVLSD 55
PRK14289 PRK14289
molecular chaperone DnaJ;
3-105 6.34e-27

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 107.22  E-value: 6.34e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRGQSRSH 82
Cdd:PRK14289   6 DYYEVLGVSKTATVDEIKKAYRKKAIQYHPDKNPGD-KEAEEKFKEAAEAYDVLSDPDKRSRYDQFGHAGVGGAAGGGGF 84

                         90       100
                 ....*....|....*....|....*
gi 24654066   83 ARHHYSTHD-FDDF-DILGGFQFAF 105
Cdd:PRK14289  85 SGEGMSMEDiFSMFgDIFGGHGGGF 109
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 4-78 2.56e-26

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 106.06  E-value: 2.56e-26
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24654066    4 YYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDnldeaNKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRGQ 78
Cdd:PTZ00037  30 LYEVLNLSKDCTTSEIKKAYRKLAIKHHPDKGGD-----PEKFKEISRAYEVLSDPEKRKIYDEYGEEGLEGGEQ 99
PRK14280 PRK14280
molecular chaperone DnaJ;
3-117 1.07e-25

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 103.65  E-value: 1.07e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDnlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKD----GLGDRGq 78
Cdd:PRK14280   5 DYYEVLGVSKSASKDEIKKAYRKLSKKYHPDINKE--EGADEKFKEISEAYEVLSDDQKRAQYDQFGHAgpnqGFGGGG- 81

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 24654066   79 srsharhhysthdFDDFDILGGFQFafrppEEVFREFFG 117
Cdd:PRK14280  82 -------------FGGGDFGGGFGF-----EDIFSSFFG 102
PRK14295 PRK14295
molecular chaperone DnaJ;
3-100 2.18e-25

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 103.00  E-value: 2.18e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNLdEANKRFRELSEAYEVLSDEKKRRIYDEyGKDGLGDRGQSRSH 82
Cdd:PRK14295  10 DYYKVLGVPKDATEAEIKKAYRKLAREYHPDANKGDA-KAEERFKEISEAYDVLSDEKKRKEYDE-ARSLFGNGGFRPGP 87

                         90
                 ....*....|....*...
gi 24654066   83 ARHHYSTHDFDDFDILGG 100
Cdd:PRK14295  88 GGGGGGGFNFDLGDLFGG 105
SEC63 COG5407
Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular ...
 3-63 3.19e-25

Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 444165 [Multi-domain]  Cd Length: 61  Bit Score: 94.68  E-value: 3.19e-25
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24654066   3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNLDeANKRFRELSEAYEVLSDEKKRR 63
Cdd:COG5407   1 DPYEVLGVAKTASADEIKKAYRKLAKKYHPDRNKGDPK-AEERFKEINEAYELLSDAEKRA 60
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
1-66 3.29e-25

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 95.56  E-value: 3.29e-25
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24654066   1 MVDYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNLDEANKRFRELSEAYEVLSDEKKRRIYD 66
Cdd:COG2214   4 LKDHYAVLGVPPDASLEEIRQAYRRLAKLLHPDRGGELKALAEELFQRLNEAYEVLSDPERRAEYD 69
PRK14276 PRK14276
chaperone protein DnaJ; Provisional
 3-117 4.02e-25

chaperone protein DnaJ; Provisional


Pssm-ID: 237653 [Multi-domain]  Cd Length: 380  Bit Score: 102.09  E-value: 4.02e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKN--PDnldeANKRFRELSEAYEVLSDEKKRRIYDEYGKD----GLGDR 76
Cdd:PRK14276   5 EYYDRLGVSKDASQDEIKKAYRKLSKKYHPDINkePG----AEEKYKEVQEAYETLSDPQKRAAYDQYGAAgangGFGGG 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 24654066   77 GQSRSharhhysthDFDDFDILGGFqfafrppEEVFREFFG 117
Cdd:PRK14276  81 AGGFG---------GFDGSGGFGGF-------EDIFSSFFG 105
PRK14297 PRK14297
molecular chaperone DnaJ;
3-117 6.49e-25

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 101.78  E-value: 6.49e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSDEKKRRIYDEYGK---DGLGDRGQS 79
Cdd:PRK14297   5 DYYEVLGLEKGASDDEIKKAFRKLAIKYHPDKNKGN-KEAEEKFKEINEAYQVLSDPQKKAQYDQFGTadfNGAGGFGSG 83

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 24654066   80 rsharhhysthDFDDFDI--LGGFqfafrppEEVFREFFG 117
Cdd:PRK14297  84 -----------GFGGFDFsdMGGF-------GDIFDSFFG 105
PRK14279 PRK14279
molecular chaperone DnaJ;
3-100 3.39e-24

molecular chaperone DnaJ;


Pssm-ID: 237655 [Multi-domain]  Cd Length: 392  Bit Score: 99.81  E-value: 3.39e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSDEKKRRIYDE----YGKDGLGDRGQ 78
Cdd:PRK14279  10 DFYKELGVSSDASAEEIKKAYRKLARELHPDANPGD-PAAEERFKAVSEAHDVLSDPAKRKEYDEtrrlFAGGGFGGRRF 88

                         90       100
                 ....*....|....*....|....*.
gi 24654066   79 SRSHA----RHHYSTHDFDDFDILGG 100
Cdd:PRK14279  89 DGGGGfggfGTGGDGAEFNLNDLFDA 114
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 3-117 1.20e-23

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 97.97  E-value: 1.20e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDnlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGdrGQSrsh 82
Cdd:PRK14283   6 DYYEVLGVDRNADKKEIKKAYRKLARKYHPDVSEE--EGAEEKFKEISEAYAVLSDDEKRQRYDQFGHAGMD--GFS--- 78

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 24654066   83 ARHHYSTHDFDdfDILGGFQFAFrppEEVFREF-FG 117
Cdd:PRK14283  79 QEDIFNNINFE--DIFQGFGFGI---GNIFDMFgFG 109
PRK14293 PRK14293
molecular chaperone DnaJ;
1-117 1.39e-23

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 97.75  E-value: 1.39e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    1 MVDYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDnlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRGqsr 80
Cdd:PRK14293   2 AADYYEILGVSRDADKDELKRAYRRLARKYHPDVNKE--PGAEDRFKEINRAYEVLSDPETRARYDQFGEAGVSGAA--- 76

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 24654066   81 sharhhysthDFDDFDILGGFQfafrppeEVFREFFG 117
Cdd:PRK14293  77 ----------GFPDMGDMGGFA-------DIFETFFS 96
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 3-108 2.59e-23

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 95.78  E-value: 2.59e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDnlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRGQSR-- 80
Cdd:PRK14299   5 DYYAILGVPKNASQDEIKKAFKKLARKYHPDVNKS--PGAEEKFKEINEAYTVLSDPEKRRIYDTYGTTAASAGWQGPpp 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 24654066   81 ----SHARHHYSTHDFDDF--------DILGGFQFAFRPP 108
Cdd:PRK14299  83 gppgGGDFSGFNVGDFSDFfqqlfggrGGFGGFGDLFGSV 122
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 1-117 5.81e-23

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 96.11  E-value: 5.81e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    1 MVDYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDnlDEANKRFRELSEAYEVLSDEKKRRIYDEYGK-DGLGDRGQs 79
Cdd:PRK14292   1 MMDYYELLGVSRTASADEIKSAYRKLALKYHPDRNKE--KGAAEKFAQINEAYAVLSDAEKRAHYDRFGTaPGAGMPGG- 77

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 24654066   80 rsharhhysthdfddfDILGGFQFafrPPEEVFREFFG 117
Cdd:PRK14292  78 ----------------DPFGGMGF---DPMDIFEQLFG 96
termin_org_DnaJ TIGR03835
terminal organelle assembly protein TopJ; This model describes TopJ (MG_200, CbpA), a DnaJ ...
 3-73 3.09e-22

terminal organelle assembly protein TopJ; This model describes TopJ (MG_200, CbpA), a DnaJ homolog and probable assembly protein of the Mycoplasma terminal organelle. The terminal organelle is involved in both cytadherence and gliding motility. [Cellular processes, Chemotaxis and motility]


Pssm-ID: 274808 [Multi-domain]  Cd Length: 871  Bit Score: 95.65  E-value: 3.09e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24654066     3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDnlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGL 73
Cdd:TIGR03835   3 DYYEVLGIDRDADEQEIKKAFRKLAKKYHPDRNKA--PDAASIFAEINEANDVLSNPKKRANYDKYGHDGV 71
PRK14288 PRK14288
molecular chaperone DnaJ;
2-105 1.14e-20

molecular chaperone DnaJ;


Pssm-ID: 172776 [Multi-domain]  Cd Length: 369  Bit Score: 89.75  E-value: 1.14e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    2 VDYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRGQSRS 81
Cdd:PRK14288   3 LSYYEILEVEKHSNQETIKKSYRKLALKYHPDRNAGD-KEAEEKFKLINEAYGVLSDEKKRALYDRYGKKGLNQAGASQS 81

                         90       100
                 ....*....|....*....|....*.
gi 24654066   82 harhhysthDFDDF--DILGGFQFAF 105
Cdd:PRK14288  82 ---------DFSDFfeDLGSFFEDAF 98
PRK14285 PRK14285
chaperone protein DnaJ; Provisional
 3-101 1.28e-20

chaperone protein DnaJ; Provisional


Pssm-ID: 172773 [Multi-domain]  Cd Length: 365  Bit Score: 89.67  E-value: 1.28e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNlDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGDRGQSRSH 82
Cdd:PRK14285   4 DYYEILGLSKGASKDEIKKAYRKIAIKYHPDKNKGN-KEAESIFKEATEAYEVLIDDNKRAQYDRFGHTAFEGGGGFEGF 82

                         90       100
                 ....*....|....*....|.
gi 24654066   83 ARHHYSTHD-FDDF-DILGGF 101
Cdd:PRK14285  83 SGGFSGFSDiFEDFgDIFDSF 103
PRK14300 PRK14300
chaperone protein DnaJ; Provisional
 3-100 1.56e-20

chaperone protein DnaJ; Provisional


Pssm-ID: 172788 [Multi-domain]  Cd Length: 372  Bit Score: 89.30  E-value: 1.56e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNpdNLDEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGLGD---RGQS 79
Cdd:PRK14300   4 DYYQILGVSKTASQADLKKAYLKLAKQYHPDTT--DAKDAEKKFKEINAAYDVLKDEQKRAAYDRFGHDAFQNqqsRGGG 81

                         90       100
                 ....*....|....*....|....
gi 24654066   80 RSHARHHYSTHD-FDDF--DILGG 100
Cdd:PRK14300  82 GNHGGFHPDINDiFGDFfsDFMGG 105
PRK10266 PRK10266
curved DNA-binding protein;
3-119 1.28e-19

curved DNA-binding protein;


Pssm-ID: 182347 [Multi-domain]  Cd Length: 306  Bit Score: 86.03  E-value: 1.28e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPD--KNPDnldeANKRFRELSEAYEVLSDEKKRRIYDEY--GKDGLGDRGQ 78
Cdd:PRK10266   5 DYYAIMGVKPTDDLKTIKTAYRRLARKYHPDvsKEPD----AEARFKEVAEAWEVLSDEQRRAEYDQLwqHRNDPQFNRQ 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 24654066   79 SRSHARHHYSTHDFDDFdilggfqfafrppeevFREFFGIH 119
Cdd:PRK10266  81 FQHGDGQSFNAEDFDDI----------------FSSIFGQH 105
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
 3-117 5.41e-17

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 79.22  E-value: 5.41e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNldEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGL-GDRGQSRS 81
Cdd:PRK14296   5 DYYEVLGVSKTASEQEIRQAYRKLAKQYHPDLNKSP--DAHDKMVEINEAADVLLDKDKRKQYDQFGHAAFdGSSGFSSN 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 24654066   82 HArhhysthDFDDF----DILGGFQFAfrppeEVFREFFG 117
Cdd:PRK14296  83 FG-------DFEDLfsnmGSSGFSSFT-----NIFSDFFG 110
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 3-69 3.20e-16

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 77.36  E-value: 3.20e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDnlDEANKRFRELSEAYEVLSDEKKRRIYDEYG 69
Cdd:PRK14287   5 DYYEVLGVDRNASVDEVKKAYRKLARKYHPDVNKA--PDAEDKFKEVKEAYDTLSDPQKKAHYDQFG 69
DjlA COG1076
DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];
1-64 2.54e-14

DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440694 [Multi-domain]  Cd Length: 75  Bit Score: 65.97  E-value: 2.54e-14
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24654066   1 MVDYYKILDVSRSATDSEVKKAYRKLALKWHPDK-----NPDNLDEANKRFRELSEAYEVLSDEKKRRI 64
Cdd:COG1076   3 LDDAFELLGLPPDADDAELKRAYRKLQREHHPDRlaaglPEEEQRLALQKAAAINEAYETLKDPRGIDL 71
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 4-73 1.53e-11

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 64.04  E-value: 1.53e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066     4 YYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNldEANKRFRELSEAYEVLSDEKKRRIYDEYGKDGL 73
Cdd:PTZ00341  575 FYDILGVGVNADMKEISERYFKLAENYYPPKRSGN--EGFHKFKKINEAYQILGDIDKKKMYNKFGYDGI 642
djlA PRK09430
co-chaperone DjlA;
3-63 8.77e-09

co-chaperone DjlA;


Pssm-ID: 236512 [Multi-domain]  Cd Length: 267  Bit Score: 54.82  E-value: 8.77e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24654066    3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDK------NPDNLDEANKRFRELSEAYEVLSDEKKRR 63
Cdd:PRK09430 201 DAYKVLGVSESDDDQEIKRAYRKLMSEHHPDKlvakglPPEMMEMAKEKAQEIQAAYELIKKQKGFK 267
ZUO1 COG5269
Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / ...
 2-66 2.05e-07

Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227594 [Multi-domain]  Cd Length: 379  Bit Score: 51.19  E-value: 2.05e-07
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24654066   2 VDYYKILDVSR---SATDSEVKKAYRKLALKWHPDKNPD----NLDEAnkrFRELSEAYEVLSDEKKRRIYD 66
Cdd:COG5269  43 VDLYALLGLSKyrtKAIPPQILKAHKKKVYKYHPDKTAAggnkGCDEF---FKLIQKAREVLGDRKLRLQYD 111
PHA03102 PHA03102
Small T antigen; Reviewed
 6-85 5.91e-04

Small T antigen; Reviewed


Pssm-ID: 222986 [Multi-domain]  Cd Length: 153  Bit Score: 39.27  E-value: 5.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654066    6 KILDVSRSATDSE--VKKAYRKLALKWHPDK--NPDNLDEAN---KRFRE-LSEAYEVLSDEKKRRIYDEYGKDGLGDRG 77
Cdd:PHA03102   9 DLLGLPRSAWGNLplMRKAYLRKCLEFHPDKggDEEKMKELNtlyKKFREsVKSLRDLDGEEDSSSEEEDVPSGYVGATF 88


                 ....*...
gi 24654066   78 QSRSHARH 85
Cdd:PHA03102  89 GDRVNALY 96
Ubl_TECR_like cd01801
ubiquitin-like (Ubl) domain found in trans-2,3-enoyl-CoA reductase (TECR) and similar proteins; ...
 5-66 5.19e-03

ubiquitin-like (Ubl) domain found in trans-2,3-enoyl-CoA reductase (TECR) and similar proteins; This family includes TECR and many TECR-like proteins, such as TECRL. TECR, also termed very-long-chain enoyl-CoA reductase, or synaptic glycoprotein SC2, or TER, or GPSN2, is a synaptic glycoprotein that catalyzes the fourth reaction in the synthesis of very long-chain fatty acids (VLCFA) which is the reduction step of the microsomal fatty acyl-elongation process. Diseases involving perturbations to normal synthesis and degradation of VLCFA (e.g. adrenoleukodystrophy and Zellweger syndrome) have significant neurological consequences. The mammalian TECR P182L mutation causes nonsyndromic mental retardation. Deletion of the yeast TECR (TSC13) homolog is lethal. TECR contains an N-terminal ubiquitin-like (Ubl) domain with a beta-grasp Ubl fold, a common structure involved in protein-protein interactions, as well as a C-terminal catalytic domain. TECRL, also termed steroid 5-alpha-reductase 2-like 2 protein (SRD5A2L2), is associated with life-threatening inherited arrhythmias displaying features of both long QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardia (CPVT). Both TECR and TECRL contain an N-terminal Ubl domain with a beta-grasp Ubl fold, and a C-terminal catalytic domain.


Pssm-ID: 340499 [Multi-domain]  Cd Length: 77  Bit Score: 34.95  E-value: 5.19e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24654066   5 YKILDVSRSATDSEVKKAYRKLALKWHPDKnpdnldeanKRFRELSEAYEVLSDEKKRRIYD 66
Cdd:cd01801  13 IITLEVSSSATVADLKKAIHKKKKKLYPER---------QRLRLEVPKGKVLKDDKTLSSYG 65
PTZ00100 PTZ00100
DnaJ chaperone protein; Provisional
 5-33 6.69e-03

DnaJ chaperone protein; Provisional


Pssm-ID: 240265  Cd Length: 116  Bit Score: 35.60  E-value: 6.69e-03
                         10        20
                 ....*....|....*....|....*....
gi 24654066    5 YKILDVSRSATDSEVKKAYRKLALKWHPD 33
Cdd:PTZ00100  68 YKILNISPTASKERIREAHKQLMLRNHPD 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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