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Conserved domains on  [gi|28573574|ref|NP_725957|]
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uncharacterized protein Dmel_CG8929, isoform B [Drosophila melanogaster]

Protein Classification

NKAP family protein( domain architecture ID 11238890)

NKAP (NF-kappa-B-activating protein) family protein, similar to Mus musculus NKAP-like protein that is a transcriptional repressor of Notch-mediated signaling and required for spermatogenesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NKAP pfam15692
NF-kappa-B-activating protein; NKAP is a family of eukaryotic proteins that interacts with ...
 39-94 1.06e-09

NF-kappa-B-activating protein; NKAP is a family of eukaryotic proteins that interacts with NF-kappa-B. It is a nuclear regulator of TNF- and IL-1-induced NF-kappa-B activation. NKAP does not interact with RIP in mammalian cells family is often found in association with pfam06047.


:

Pssm-ID: 464805  Cd Length: 84  Bit Score: 55.15  E-value: 1.06e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 28573574    39 NVMKKARANttnDYWDKKLIEAEEKDPNRWRHTGYKKMYIQGESSSGESERDGREG 94
Cdd:pfam15692   1 NDKREARRQ---WYWNRKLYEREAGDPDRWGHSGYKELYPEEFESDSDEHTGVEGD 53
 
Name Accession Description Interval E-value
NKAP pfam15692
NF-kappa-B-activating protein; NKAP is a family of eukaryotic proteins that interacts with ...
 39-94 1.06e-09

NF-kappa-B-activating protein; NKAP is a family of eukaryotic proteins that interacts with NF-kappa-B. It is a nuclear regulator of TNF- and IL-1-induced NF-kappa-B activation. NKAP does not interact with RIP in mammalian cells family is often found in association with pfam06047.


Pssm-ID: 464805  Cd Length: 84  Bit Score: 55.15  E-value: 1.06e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 28573574    39 NVMKKARANttnDYWDKKLIEAEEKDPNRWRHTGYKKMYIQGESSSGESERDGREG 94
Cdd:pfam15692   1 NDKREARRQ---WYWNRKLYEREAGDPDRWGHSGYKELYPEEFESDSDEHTGVEGD 53
 
Name Accession Description Interval E-value
NKAP pfam15692
NF-kappa-B-activating protein; NKAP is a family of eukaryotic proteins that interacts with ...
 39-94 1.06e-09

NF-kappa-B-activating protein; NKAP is a family of eukaryotic proteins that interacts with NF-kappa-B. It is a nuclear regulator of TNF- and IL-1-induced NF-kappa-B activation. NKAP does not interact with RIP in mammalian cells family is often found in association with pfam06047.


Pssm-ID: 464805  Cd Length: 84  Bit Score: 55.15  E-value: 1.06e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 28573574    39 NVMKKARANttnDYWDKKLIEAEEKDPNRWRHTGYKKMYIQGESSSGESERDGREG 94
Cdd:pfam15692   1 NDKREARRQ---WYWNRKLYEREAGDPDRWGHSGYKELYPEEFESDSDEHTGVEGD 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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