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Conserved domains on  [gi|671162303|ref|NP_726249|]
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uncharacterized protein Dmel_CG30271, isoform H [Drosophila melanogaster]

Protein Classification

ankyrin repeat domain-containing protein( domain architecture ID 12120816)

ankyrin repeat (ANK) domain-containing protein mediates specific protein-protein interactions without necessarily recognizing specific primary sequences which allows for one ankyrin repeat domain to recognize and bind to a variety of intracellular substrates and may be involved in a wide array of functions

CATH:  1.25.40.20
Gene Ontology:  GO:0005515
PubMed:  33435370|15152081|17176038
SCOP:  4000366

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Ank_2 pfam12796
Ankyrin repeats (3 copies);
86-183 2.26e-11

Ankyrin repeats (3 copies);


:

Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 60.13  E-value: 2.26e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303   86 LHQAVIDNNLETVQAQLEPPVPsalVTCKDGNGLNIIHKAAGLGHTKLLEYLVgiwPEGAHETDITGKTPLHWAASaKNN 165
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGAD---ANLQDKNGRTALHLAAKNGHLEIVKLLL---EHADVNLKDNGRTALHYAAR-SGH 73

                          90
                  ....*....|....*...
gi 671162303  166 MRCYTLLTQAGCDEEAVD 183
Cdd:pfam12796  74 LEIVKLLLEKGADINVKD 91
2A1904 super family cl36772
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 231-453 1.61e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


The actual alignment was detected with superfamily member TIGR00927:

Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 44.60  E-value: 1.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303   231 DNGAGGDASSKKLDIK----VPPSVNGRKSLDDSLENTSELDTNDGTSANEDDDlskvdaEPEAEVASPLQRRPETPATF 306
Cdd:TIGR00927  692 EQEGEGEIEAKEADHKgeteAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEG------EGEAEGKHEVETEGDRKETE 765

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303   307 NTINGDGDGEDSEPENigrAVSANGGGEAEENGVGQDEGGGGDavivENGEVREEAPEEDQPTEPEDVGKPEESAtESEL 386
Cdd:TIGR00927  766 HEGETEAEGKEDEDEG---EIQAGEDGEMKGDEGAEGKVEHEG----ETEAGEKDEHEGQSETQADDTEVKDETG-EQEL 837

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 671162303   387 EGNKKTEVEPEEPEEPVEHVEHVEQAVEQAEQVEQAEQVEQAEQVEQAEQVEHEKQETVDEPESNAK 453
Cdd:TIGR00927  838 NAENQGEAKQDEKGVDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPETRQK 904
 
Name Accession Description Interval E-value
Ank_2 pfam12796
Ankyrin repeats (3 copies);
86-183 2.26e-11

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 60.13  E-value: 2.26e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303   86 LHQAVIDNNLETVQAQLEPPVPsalVTCKDGNGLNIIHKAAGLGHTKLLEYLVgiwPEGAHETDITGKTPLHWAASaKNN 165
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGAD---ANLQDKNGRTALHLAAKNGHLEIVKLLL---EHADVNLKDNGRTALHYAAR-SGH 73

                          90
                  ....*....|....*...
gi 671162303  166 MRCYTLLTQAGCDEEAVD 183
Cdd:pfam12796  74 LEIVKLLLEKGADINVKD 91
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
86-225 3.11e-07

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 51.88  E-value: 3.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303  86 LHQAVIDNNLETVQAQLEPPvpsALVTCKDGNGLNIIHKAAGLGHTKLLEYLVGiwpEGA--HETDITGKTPLHWAASaK 163
Cdd:COG0666  124 LHLAAYNGNLEIVKLLLEAG---ADVNAQDNDGNTPLHLAAANGNLEIVKLLLE---AGAdvNARDNDGETPLHLAAE-N 196

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 671162303 164 NNMRCYTLLTQAGCDEEAVDYKMKTPSYY--RHKPHEIERAFLVYVPDAPRVSPDSATDWDALC 225
Cdd:COG0666  197 GHLEIVKLLLEAGADVNAKDNDGKTALDLaaENGNLEIVKLLLEAGADLNAKDKDGLTALLLAA 260
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 231-453 1.61e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 44.60  E-value: 1.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303   231 DNGAGGDASSKKLDIK----VPPSVNGRKSLDDSLENTSELDTNDGTSANEDDDlskvdaEPEAEVASPLQRRPETPATF 306
Cdd:TIGR00927  692 EQEGEGEIEAKEADHKgeteAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEG------EGEAEGKHEVETEGDRKETE 765

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303   307 NTINGDGDGEDSEPENigrAVSANGGGEAEENGVGQDEGGGGDavivENGEVREEAPEEDQPTEPEDVGKPEESAtESEL 386
Cdd:TIGR00927  766 HEGETEAEGKEDEDEG---EIQAGEDGEMKGDEGAEGKVEHEG----ETEAGEKDEHEGQSETQADDTEVKDETG-EQEL 837

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 671162303   387 EGNKKTEVEPEEPEEPVEHVEHVEQAVEQAEQVEQAEQVEQAEQVEQAEQVEHEKQETVDEPESNAK 453
Cdd:TIGR00927  838 NAENQGEAKQDEKGVDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPETRQK 904
PHA03095 PHA03095
ankyrin-like protein; Provisional
 146-210 3.42e-04

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 43.09  E-value: 3.42e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 671162303 146 HETDITGKTPLHWAASAKNNMRCYTLLtQAGCDEEAVDYKMKTP--SYYRHKPHEIERAFLVYVPDA 210
Cdd:PHA03095 251 NARNRYGQTPLHYAAVFNNPRACRRLI-ALGADINAVSSDGNTPlsLMVRNNNGRAVRAALAKNPSA 316
rne PRK10811
ribonuclease E; Reviewed
 334-487 1.65e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 41.18  E-value: 1.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303  334 EAEENGVGQDEGGGGDAVIVENGEVREEAPEEDQPTEPEDVGKPEESATESELEGNKKTEVEPEEPEEPVEHVEHVEQAV 413
Cdd:PRK10811  852 DVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVI 931

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303  414 EQAEQVEQAEQVEQAEQV-------EQAEQVEHEKQETVDEPESNAKDEAdPEVAAMSVEEREPESENDNDDDDEVQMGV 486
Cdd:PRK10811  932 TESDVAVAQEVAEHAEPVvepqdetADIEEAAETAEVVVAEPEVVAQPAA-PVVAEVAAEVETVTAVEPEVAPAQVPEAT 1010


                  .
gi 671162303  487 L 487
Cdd:PRK10811 1011 V 1011
ZipA COG3115
Cell division protein ZipA, interacts with FtsZ [Cell cycle control, cell division, chromosome ...
 334-465 7.90e-03

Cell division protein ZipA, interacts with FtsZ [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442349 [Multi-domain]  Cd Length: 298  Bit Score: 38.13  E-value: 7.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303 334 EAEENGVGQDEGGGGDAVIVENGEVREEAPEEDQPTEP----EDVGKPEESATESELEGNKKTEVEPEEPEEPVEHVEHV 409
Cdd:COG3115   32 SSFRDKPSKRDVLLDDDGIGEVRVVAAEAPERVEPEASfdaeDEVREPDQEEVDPLLDDEADIEAAPAEPVRWAGTAAAV 111

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 671162303 410 EQAVEQAEQVEQAEQVEQAEQvEQAEQVEHEKQETVDEPESNAKDEADPEVAAMSV 465
Cdd:COG3115  112 EPAPEQEAYEEAGPAGESAEQ-EDAPAEEPEAEAPAEEALAAELCAEPEEVIVLNV 166
 
Name Accession Description Interval E-value
Ank_2 pfam12796
Ankyrin repeats (3 copies);
86-183 2.26e-11

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 60.13  E-value: 2.26e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303   86 LHQAVIDNNLETVQAQLEPPVPsalVTCKDGNGLNIIHKAAGLGHTKLLEYLVgiwPEGAHETDITGKTPLHWAASaKNN 165
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGAD---ANLQDKNGRTALHLAAKNGHLEIVKLLL---EHADVNLKDNGRTALHYAAR-SGH 73

                          90
                  ....*....|....*...
gi 671162303  166 MRCYTLLTQAGCDEEAVD 183
Cdd:pfam12796  74 LEIVKLLLEKGADINVKD 91
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
86-225 3.11e-07

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 51.88  E-value: 3.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303  86 LHQAVIDNNLETVQAQLEPPvpsALVTCKDGNGLNIIHKAAGLGHTKLLEYLVGiwpEGA--HETDITGKTPLHWAASaK 163
Cdd:COG0666  124 LHLAAYNGNLEIVKLLLEAG---ADVNAQDNDGNTPLHLAAANGNLEIVKLLLE---AGAdvNARDNDGETPLHLAAE-N 196

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 671162303 164 NNMRCYTLLTQAGCDEEAVDYKMKTPSYY--RHKPHEIERAFLVYVPDAPRVSPDSATDWDALC 225
Cdd:COG0666  197 GHLEIVKLLLEAGADVNAKDNDGKTALDLaaENGNLEIVKLLLEAGADLNAKDKDGLTALLLAA 260
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
63-204 4.05e-06

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 48.41  E-value: 4.05e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303  63 ASNNGR---VKRFLA--AVPHVMNAIKD--LHQAVIDNNLETVQAQLEPPvpsALVTCKDGNGLNIIHKAAGLGHTKLLE 135
Cdd:COG0666  127 AAYNGNleiVKLLLEagADVNAQDNDGNtpLHLAAANGNLEIVKLLLEAG---ADVNARDNDGETPLHLAAENGHLEIVK 203

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 671162303 136 YLVGiwpEGA--HETDITGKTPLHWAAsAKNNMRCYTLLTQAGCDEEAVDYKMKTPSYYRHKPHEIERAFL 204
Cdd:COG0666  204 LLLE---AGAdvNAKDNDGKTALDLAA-ENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKL 270
Ank_4 pfam13637
Ankyrin repeats (many copies);
86-138 2.33e-05

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 41.88  E-value: 2.33e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 671162303   86 LHQAVIDNNLETVQAQLEPPVPsalVTCKDGNGLNIIHKAAGLGHTKLLEYLV 138
Cdd:pfam13637   5 LHAAAASGHLELLRLLLEKGAD---INAVDGNGETALHFAASNGNVEVLKLLL 54
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 231-453 1.61e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 44.60  E-value: 1.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303   231 DNGAGGDASSKKLDIK----VPPSVNGRKSLDDSLENTSELDTNDGTSANEDDDlskvdaEPEAEVASPLQRRPETPATF 306
Cdd:TIGR00927  692 EQEGEGEIEAKEADHKgeteAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEG------EGEAEGKHEVETEGDRKETE 765

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303   307 NTINGDGDGEDSEPENigrAVSANGGGEAEENGVGQDEGGGGDavivENGEVREEAPEEDQPTEPEDVGKPEESAtESEL 386
Cdd:TIGR00927  766 HEGETEAEGKEDEDEG---EIQAGEDGEMKGDEGAEGKVEHEG----ETEAGEKDEHEGQSETQADDTEVKDETG-EQEL 837

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 671162303   387 EGNKKTEVEPEEPEEPVEHVEHVEQAVEQAEQVEQAEQVEQAEQVEQAEQVEHEKQETVDEPESNAK 453
Cdd:TIGR00927  838 NAENQGEAKQDEKGVDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPETRQK 904
Ank_4 pfam13637
Ankyrin repeats (many copies);
118-164 2.92e-04

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 38.79  E-value: 2.92e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 671162303  118 GLNIIHKAAGLGHTKLLEYLVGIWPEgAHETDITGKTPLHWAASAKN 164
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEKGAD-INAVDGNGETALHFAASNGN 46
PHA03095 PHA03095
ankyrin-like protein; Provisional
 146-210 3.42e-04

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 43.09  E-value: 3.42e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 671162303 146 HETDITGKTPLHWAASAKNNMRCYTLLtQAGCDEEAVDYKMKTP--SYYRHKPHEIERAFLVYVPDA 210
Cdd:PHA03095 251 NARNRYGQTPLHYAAVFNNPRACRRLI-ALGADINAVSSDGNTPlsLMVRNNNGRAVRAALAKNPSA 316
Ank pfam00023
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 152-183 7.83e-04

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.


Pssm-ID: 459634 [Multi-domain]  Cd Length: 34  Bit Score: 36.88  E-value: 7.83e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 671162303  152 GKTPLHWAASAKNNMRCYTLLTQAGCDEEAVD 183
Cdd:pfam00023   2 GNTPLHLAAGRRGNLEIVKLLLSKGADVNARD 33
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 255-469 8.44e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 42.29  E-value: 8.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303   255 KSLDDSLENTSELDTNDGTSAN----EDDDLSKVDAEPEAEVASPLQRRPEtpatfNTINGDGDGEDsEPENIGRAVSAN 330
Cdd:TIGR00927  632 KGDVAEAEHTGERTGEEGERPTeaegENGEESGGEAEQEGETETKGENESE-----GEIPAERKGEQ-EGEGEIEAKEAD 705

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303   331 GGGEAEENGvgqdeggggdavIVENGEVREEAPEEDQPTEPEDVGKPEESATESELEGNKKTEVEPEEPEEPVEHVEHVE 410
Cdd:TIGR00927  706 HKGETEAEE------------VEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAE 773

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 671162303   411 QAVEQAE-QVEQAEQVEQAEQVEQAEQVEHEKQETVDEPESNAKDE---ADPEVAAMSVEERE 469
Cdd:TIGR00927  774 GKEDEDEgEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSetqADDTEVKDETGEQE 836
rne PRK10811
ribonuclease E; Reviewed
 334-487 1.65e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 41.18  E-value: 1.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303  334 EAEENGVGQDEGGGGDAVIVENGEVREEAPEEDQPTEPEDVGKPEESATESELEGNKKTEVEPEEPEEPVEHVEHVEQAV 413
Cdd:PRK10811  852 DVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVI 931

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303  414 EQAEQVEQAEQVEQAEQV-------EQAEQVEHEKQETVDEPESNAKDEAdPEVAAMSVEEREPESENDNDDDDEVQMGV 486
Cdd:PRK10811  932 TESDVAVAQEVAEHAEPVvepqdetADIEEAAETAEVVVAEPEVVAQPAA-PVVAEVAAEVETVTAVEPEVAPAQVPEAT 1010


                  .
gi 671162303  487 L 487
Cdd:PRK10811 1011 V 1011
PTZ00121 PTZ00121
MAEBL; Provisional
 357-467 1.65e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.28  E-value: 1.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303  357 EVR--EEAPEEDQPTEPEDVGKPEESATESELEGNKKtevEPEEPEEPVEHVEHVEQAVEQAEQVEQAEQVEQAEQVEQA 434
Cdd:PTZ00121 1216 EARkaEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNE---EIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA 1292

                          90       100       110
                  ....*....|....*....|....*....|....
gi 671162303  435 EQVEH-EKQETVDEPESNAKDEADPEVAAMSVEE 467
Cdd:PTZ00121 1293 DEAKKaEEKKKADEAKKKAEEAKKADEAKKKAEE 1326
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
81-189 4.15e-03

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 39.17  E-value: 4.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303  81 NAIKDLHQAVIDNNLETVQAQLEPPVPSALvtcKDGNGLNIIHKAAGLGHTKLLEYLVGiwpEGA--HETDITGKTPLHW 158
Cdd:COG0666   53 LGALLLLAAALAGDLLVALLLLAAGADINA---KDDGGNTLLHAAARNGDLEIVKLLLE---AGAdvNARDKDGETPLHL 126

                         90       100       110
                 ....*....|....*....|....*....|.
gi 671162303 159 AAsAKNNMRCYTLLTQAGCDEEAVDYKMKTP 189
Cdd:COG0666  127 AA-YNGNLEIVKLLLEAGADVNAQDNDGNTP 156
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 268-457 4.46e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 39.59  E-value: 4.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303   268 DTNDGTSANEDDDLSKVDAEPEAEVasPLQRR------PETPATFNTINGDGDGEDSEPENIGRA--VSANGGGEAEENG 339
Cdd:TIGR00927  661 EESGGEAEQEGETETKGENESEGEI--PAERKgeqegeGEIEAKEADHKGETEAEEVEHEGETEAegTEDEGEIETGEEG 738

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303   340 VGQDEGGGGDAVIVENGEVREEAPEEDQPTEPEDVGKPEESATESELEGNkktevepeepeEPVEHVEHVEQAVEQAEQV 419
Cdd:TIGR00927  739 EEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEIQAGED-----------GEMKGDEGAEGKVEHEGET 807

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 671162303   420 EQAEQVEQAEQVEQAEQVEHEKQETvDEPESNAKDEAD 457
Cdd:TIGR00927  808 EAGEKDEHEGQSETQADDTEVKDET-GEQELNAENQGE 844
ZipA COG3115
Cell division protein ZipA, interacts with FtsZ [Cell cycle control, cell division, chromosome ...
 334-465 7.90e-03

Cell division protein ZipA, interacts with FtsZ [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442349 [Multi-domain]  Cd Length: 298  Bit Score: 38.13  E-value: 7.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303 334 EAEENGVGQDEGGGGDAVIVENGEVREEAPEEDQPTEP----EDVGKPEESATESELEGNKKTEVEPEEPEEPVEHVEHV 409
Cdd:COG3115   32 SSFRDKPSKRDVLLDDDGIGEVRVVAAEAPERVEPEASfdaeDEVREPDQEEVDPLLDDEADIEAAPAEPVRWAGTAAAV 111

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 671162303 410 EQAVEQAEQVEQAEQVEQAEQvEQAEQVEHEKQETVDEPESNAKDEADPEVAAMSV 465
Cdd:COG3115  112 EPAPEQEAYEEAGPAGESAEQ-EDAPAEEPEAEAPAEEALAAELCAEPEEVIVLNV 166
PTZ00121 PTZ00121
MAEBL; Provisional
 334-482 8.11e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.97  E-value: 8.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671162303  334 EAEENGVGQDEGGGGDAVIVENGEVREEAPEEDQPTEPEDVGKPEESATESEleGNKKTEVEPEEPEEPVEHVEHVEQAV 413
Cdd:PTZ00121 1627 KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAE--EAKKAEEDEKKAAEALKKEAEEAKKA 1704

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 671162303  414 EQ-----AEQVEQAEQVEQAEQVE--QAEQVEHEKQETVDEPESNAKDEADPEVAAMSVEEREPESENDNDDDDEV 482
Cdd:PTZ00121 1705 EElkkkeAEEKKKAEELKKAEEENkiKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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