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Conserved domains on  [gi|24665293|ref|NP_730162|]
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1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform D [Drosophila melanogaster]

Protein Classification

lysophospholipid acyltransferase family protein( domain architecture ID 11240680)

lysophospholipid acyltransferase (LPLAT) family protein may act as an acyltransferase of a de novo or remodeling pathway of glycerophospholipid biosynthesis, catalyzing the incorporation of an acyl group from either acyl-CoAs or acyl-acyl carrier proteins (acyl-ACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Acyltransf_C pfam16076
Acyltransferase C-terminus; This domain is found at the C-terminus of several different ...
 3-82 1.71e-33

Acyltransferase C-terminus; This domain is found at the C-terminus of several different acyltransferases including 1-acyl-sn-glycerol-3-phosphate acyltransferase, acyl-CoA:lysophosphatidylglycerol acyltransferase 1 and lysocardiolipin acyltransferase 1.


:

Pssm-ID: 465006 [Multi-domain]  Cd Length: 74  Bit Score: 112.28  E-value: 1.71e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24665293     3 SLLHGKSVEPHLLMRRIPLEQVPEDEKEAAAWLQNLFVEKDKIIDSFLETGSFFktsgikEVPAYVNKRRLCSLVNFVCW 82
Cdd:pfam16076   1 SLLNGKPSEVHMYIRRIPLEELPEDEEELAQWLHDLFVEKDKLLDYFYETGTFF------PGKEHIIPRRLKSLLVFIFW 74
 
Name Accession Description Interval E-value
Acyltransf_C pfam16076
Acyltransferase C-terminus; This domain is found at the C-terminus of several different ...
 3-82 1.71e-33

Acyltransferase C-terminus; This domain is found at the C-terminus of several different acyltransferases including 1-acyl-sn-glycerol-3-phosphate acyltransferase, acyl-CoA:lysophosphatidylglycerol acyltransferase 1 and lysocardiolipin acyltransferase 1.


Pssm-ID: 465006 [Multi-domain]  Cd Length: 74  Bit Score: 112.28  E-value: 1.71e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24665293     3 SLLHGKSVEPHLLMRRIPLEQVPEDEKEAAAWLQNLFVEKDKIIDSFLETGSFFktsgikEVPAYVNKRRLCSLVNFVCW 82
Cdd:pfam16076   1 SLLNGKPSEVHMYIRRIPLEELPEDEEELAQWLHDLFVEKDKLLDYFYETGTFF------PGKEHIIPRRLKSLLVFIFW 74
PLN02510 PLN02510
probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
 11-93 7.92e-11

probable 1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 178126 [Multi-domain]  Cd Length: 374  Bit Score: 58.56  E-value: 7.92e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24665293   11 EPHLLMRRIPLEQVPEDEKEAAAWLQNLFVEKDKIIDSFLETGSFFKTSGIKEVPAyvnkrrLCSLVNFVcwAVFSLSCI 90
Cdd:PLN02510 254 EVHIHIRRIPLKQIPTSEDEVSAWLMDRFQLKDQLLSDFYAQGHFPNEGTEGELST------LKCLANFL--AVIALTTV 325


                 ...
gi 24665293   91 FYY 93
Cdd:PLN02510 326 FTY 328
 
Name Accession Description Interval E-value
Acyltransf_C pfam16076
Acyltransferase C-terminus; This domain is found at the C-terminus of several different ...
 3-82 1.71e-33

Acyltransferase C-terminus; This domain is found at the C-terminus of several different acyltransferases including 1-acyl-sn-glycerol-3-phosphate acyltransferase, acyl-CoA:lysophosphatidylglycerol acyltransferase 1 and lysocardiolipin acyltransferase 1.


Pssm-ID: 465006 [Multi-domain]  Cd Length: 74  Bit Score: 112.28  E-value: 1.71e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24665293     3 SLLHGKSVEPHLLMRRIPLEQVPEDEKEAAAWLQNLFVEKDKIIDSFLETGSFFktsgikEVPAYVNKRRLCSLVNFVCW 82
Cdd:pfam16076   1 SLLNGKPSEVHMYIRRIPLEELPEDEEELAQWLHDLFVEKDKLLDYFYETGTFF------PGKEHIIPRRLKSLLVFIFW 74
PLN02510 PLN02510
probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
 11-93 7.92e-11

probable 1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 178126 [Multi-domain]  Cd Length: 374  Bit Score: 58.56  E-value: 7.92e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24665293   11 EPHLLMRRIPLEQVPEDEKEAAAWLQNLFVEKDKIIDSFLETGSFFKTSGIKEVPAyvnkrrLCSLVNFVcwAVFSLSCI 90
Cdd:PLN02510 254 EVHIHIRRIPLKQIPTSEDEVSAWLMDRFQLKDQLLSDFYAQGHFPNEGTEGELST------LKCLANFL--AVIALTTV 325


                 ...
gi 24665293   91 FYY 93
Cdd:PLN02510 326 FTY 328
PLN02380 PLN02380
1-acyl-sn-glycerol-3-phosphate acyltransferase
 1-133 2.31e-09

1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 178006 [Multi-domain]  Cd Length: 376  Bit Score: 54.36  E-value: 2.31e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24665293    1 MLSLLHGKSVEPHLLMRRIPLEQVPEDEKEAAAWLQNLFVEKDKIIDSFLETGSFfktsGIKEvpaYVNKRR-LCSLVNF 79
Cdd:PLN02380 237 MLRIFRGQSSVVHVHIKRHSMKELPETDDGIAQWCKDVFVAKDALLDKHFAEDTF----GDQE---YQDIGRpKKSLIVV 309

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 24665293   80 VCWAVFSLSCIFYYVITSLLAANWTAFITALSVLGLFYWLMGQAINKTQISKAS 133
Cdd:PLN02380 310 ISWACLLILGAIKFLQWLSLLSSWKGIASLAAGLVIVTILMQILIESSQSERST 363
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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