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Conserved domains on  [gi|24666053|ref|NP_730294|]
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Ccn [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TSP1_spondin super family cl46269
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 118-163 1.67e-06

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


The actual alignment was detected with superfamily member pfam19035:

Pssm-ID: 480609  Cd Length: 44  Bit Score: 44.63  E-value: 1.67e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 24666053   118 CHNSTTsgNWTACSRSCGLGTATRHTTTHAGCHQLSNLRLCENRRC 163
Cdd:pfam19035   1 CEEQST--EWSPCSKTCGMGVSTRVSNDNAECKLVTETRLCQLRPC 44
VWC super family cl17735
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 41-104 4.55e-03

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


The actual alignment was detected with superfamily member smart00214:

Pssm-ID: 450195  Cd Length: 59  Bit Score: 35.57  E-value: 4.55e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24666053     41 CSVGNTTFAHGVTFKLDCKTQCVCENGRH-ACSTL-CPneqlpapeDTISCRSPRLVEVPGHCCKM 104
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGTTvLCDPVeCP--------PPPDCPNPERVKPPGECCPR 58
 
Name Accession Description Interval E-value
TSP1_CCN pfam19035
CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in ...
 118-163 1.67e-06

CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in matricellular CCN proteins that have an alternative disulphide binding pattern compared to the canonical TSP1 domains.


Pssm-ID: 465952  Cd Length: 44  Bit Score: 44.63  E-value: 1.67e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 24666053   118 CHNSTTsgNWTACSRSCGLGTATRHTTTHAGCHQLSNLRLCENRRC 163
Cdd:pfam19035   1 CEEQST--EWSPCSKTCGMGVSTRVSNDNAECKLVTETRLCQLRPC 44
VWC smart00214
von Willebrand factor (vWF) type C domain;
41-104 4.55e-03

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 35.57  E-value: 4.55e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24666053     41 CSVGNTTFAHGVTFKLDCKTQCVCENGRH-ACSTL-CPneqlpapeDTISCRSPRLVEVPGHCCKM 104
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGTTvLCDPVeCP--------PPPDCPNPERVKPPGECCPR 58
 
Name Accession Description Interval E-value
TSP1_CCN pfam19035
CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in ...
 118-163 1.67e-06

CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in matricellular CCN proteins that have an alternative disulphide binding pattern compared to the canonical TSP1 domains.


Pssm-ID: 465952  Cd Length: 44  Bit Score: 44.63  E-value: 1.67e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 24666053   118 CHNSTTsgNWTACSRSCGLGTATRHTTTHAGCHQLSNLRLCENRRC 163
Cdd:pfam19035   1 CEEQST--EWSPCSKTCGMGVSTRVSNDNAECKLVTETRLCQLRPC 44
VWC smart00214
von Willebrand factor (vWF) type C domain;
41-104 4.55e-03

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 35.57  E-value: 4.55e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24666053     41 CSVGNTTFAHGVTFKLDCKTQCVCENGRH-ACSTL-CPneqlpapeDTISCRSPRLVEVPGHCCKM 104
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGTTvLCDPVeCP--------PPPDCPNPERVKPPGECCPR 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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