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Conserved domains on  [gi|24645822|ref|NP_731529|]
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adenylate kinase 3, isoform B [Drosophila melanogaster]

Protein Classification

nucleoside monophosphate kinase( domain architecture ID 11492251)

nucleoside monophosphate kinase catalyzes the transfer of the terminal phosphoryl group from a nucleoside triphosphate, usually ATP, to a nucleoside monophosphate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 7-211 1.75e-100

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


:

Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 289.90  E-value: 1.75e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822     7 RAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVG--NRS 84
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDdnENG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    85 YILDGFPRNIAQAEALAA--REQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQREDD 162
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDAllEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDD 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 24645822   163 KPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKG-KQTKEIWPMMELFLN 211
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGnGPIDEVWKRILEALK 210
 
Name Accession Description Interval E-value
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 7-211 1.75e-100

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 289.90  E-value: 1.75e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822     7 RAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVG--NRS 84
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDdnENG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    85 YILDGFPRNIAQAEALAA--REQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQREDD 162
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDAllEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDD 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 24645822   163 KPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKG-KQTKEIWPMMELFLN 211
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGnGPIDEVWKRILEALK 210
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 7-203 2.47e-87

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 256.59  E-value: 2.47e-87
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   7 RAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVGNRS-Y 85
Cdd:COG0563   2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANgF 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822  86 ILDGFPRNIAQAEAL-----AAREQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQRE 160
Cdd:COG0563  82 ILDGFPRTVAQAEALdellaELGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRA 161

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....
gi 24645822 161 DDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQT-KEIW 203
Cdd:COG0563 162 DDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSiEEVT 205
adk PRK00279
adenylate kinase; Reviewed
 7-203 1.86e-84

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 249.30  E-value: 1.86e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    7 RAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVGNRS-Y 85
Cdd:PRK00279   2 RLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNgF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   86 ILDGFPRNIAQAEAL-----AAREQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQRE 160
Cdd:PRK00279  82 LLDGFPRTIPQAEALdemlkELGIKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQRA 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 24645822  161 DDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQT-KEIW 203
Cdd:PRK00279 162 DDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSiDEVF 205
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 7-201 2.46e-81

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 240.60  E-value: 2.46e-81
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   7 RAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARI-TEVGNRSY 85
Cdd:cd01428   1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLkKPDCKKGF 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822  86 ILDGFPRNIAQAEAL----AAREQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIgfknpkvpGKDDVTGEPLMQRED 161
Cdd:cd01428  81 ILDGFPRTVDQAEALdellDEGIKPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSD 152

                       170       180       190       200
                ....*....|....*....|....*....|....*....|
gi 24645822 162 DKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQTKE 201
Cdd:cd01428 153 DNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDID 192
ADK pfam00406
Adenylate kinase;
10-188 3.86e-78

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 232.20  E-value: 3.86e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    10 IIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARIT-EVGNRSYILD 88
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEqNDCKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    89 GFPRNIAQAEAL----AAREQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQREDDKP 164
Cdd:pfam00406  81 GFPRTVPQAEALeellERGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|....
gi 24645822   165 HVVAKRLELYDEVMSPVIAWYEKK 188
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYYKKK 184
 
Name Accession Description Interval E-value
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 7-211 1.75e-100

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 289.90  E-value: 1.75e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822     7 RAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVG--NRS 84
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDdnENG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    85 YILDGFPRNIAQAEALAA--REQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQREDD 162
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDAllEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDD 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 24645822   163 KPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKG-KQTKEIWPMMELFLN 211
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGnGPIDEVWKRILEALK 210
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 7-203 2.47e-87

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 256.59  E-value: 2.47e-87
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   7 RAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVGNRS-Y 85
Cdd:COG0563   2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANgF 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822  86 ILDGFPRNIAQAEAL-----AAREQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQRE 160
Cdd:COG0563  82 ILDGFPRTVAQAEALdellaELGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRA 161

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....
gi 24645822 161 DDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQT-KEIW 203
Cdd:COG0563 162 DDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSiEEVT 205
adk PRK00279
adenylate kinase; Reviewed
 7-203 1.86e-84

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 249.30  E-value: 1.86e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    7 RAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVGNRS-Y 85
Cdd:PRK00279   2 RLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNgF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   86 ILDGFPRNIAQAEAL-----AAREQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQRE 160
Cdd:PRK00279  82 LLDGFPRTIPQAEALdemlkELGIKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQRA 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 24645822  161 DDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQT-KEIW 203
Cdd:PRK00279 162 DDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSiDEVF 205
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 7-201 2.46e-81

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 240.60  E-value: 2.46e-81
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   7 RAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARI-TEVGNRSY 85
Cdd:cd01428   1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLkKPDCKKGF 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822  86 ILDGFPRNIAQAEAL----AAREQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIgfknpkvpGKDDVTGEPLMQRED 161
Cdd:cd01428  81 ILDGFPRTVDQAEALdellDEGIKPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSD 152

                       170       180       190       200
                ....*....|....*....|....*....|....*....|
gi 24645822 162 DKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQTKE 201
Cdd:cd01428 153 DNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDID 192
ADK pfam00406
Adenylate kinase;
10-188 3.86e-78

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 232.20  E-value: 3.86e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    10 IIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARIT-EVGNRSYILD 88
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEqNDCKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    89 GFPRNIAQAEAL----AAREQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQREDDKP 164
Cdd:pfam00406  81 GFPRTVPQAEALeellERGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|....
gi 24645822   165 HVVAKRLELYDEVMSPVIAWYEKK 188
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYYKKK 184
PLN02674 PLN02674
adenylate kinase
 7-202 1.55e-53

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 171.99  E-value: 1.55e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    7 RAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVG-NRSY 85
Cdd:PLN02674  33 RLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVGIIDEAMKKPScQKGF 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   86 ILDGFPRNIAQAEAL---AARE--QIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQRE 160
Cdd:PLN02674 113 ILDGFPRTVVQAQKLdemLAKQgaKIDKVLNFAIDDAILEERITGRWIHPSSGRTYHTKFAPPKVPGVDDVTGEPLIQRK 192

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 24645822  161 DDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKG-KQTKEI 202
Cdd:PLN02674 193 DDTAAVLKSRLEAFHKQTEPVIDYYAKKGVVANLHAeKPPKEV 235
PRK14530 PRK14530
adenylate kinase; Provisional
 7-214 1.90e-45

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 150.32  E-value: 1.90e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    7 RAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKN-----TELGKkAKQYIAEGKLVPDAIVTKTMLARITEVG 81
Cdd:PRK14530   5 RILLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALRANKQMDisdmdTEYDT-PGEYMDAGELVPDAVVNEIVEEALSDAD 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   82 nrSYILDGFPRNIAQAEALAAREQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQRED 161
Cdd:PRK14530  84 --GFVLDGYPRNLEQAEYLESITDLDVVLYLDVSEEELVDRLTGRRVCPDCGANYHVEFNQPEEEGVCDECGGELIQRDD 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 24645822  162 DKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQT-KEIWPMMELFLNDRI 214
Cdd:PRK14530 162 DTEETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTpDEVWADIQDAIDDAT 215
PLN02842 PLN02842
nucleotide kinase
 9-202 6.50e-41

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 145.39  E-value: 6.50e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    9 VIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARIT--EVGNRSYI 86
Cdd:PLN02842   1 MISGAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGRLSreDAKEKGWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   87 LDGFPRNIAQAEALAA-REQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFknpkVPGKDDVTGEPLMQREDDKPH 165
Cdd:PLN02842  81 LDGYPRSFAQAQSLEKlKIRPDIFILLDVPDEILIDRCVGRRLDPVTGKIYHIKN----FPPESEEIKARLITRPDDTEE 156

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 24645822  166 VVAKRLELYDEVMSPVIAWYEKkgLVATFKGKQTKEI 202
Cdd:PLN02842 157 KVKARLQIYKKNAEAILSTYSD--IMVKIDGNRPKEV 191
adk PRK02496
adenylate kinase; Provisional
 7-201 9.68e-38

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 129.48  E-value: 9.68e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    7 RAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVGNRS-Y 85
Cdd:PRK02496   3 RLIFLGPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTPLGIKAQGYMDKGELVPDQLVLDLVQERLQQPDAANgW 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   86 ILDGFPRNIAQAEALAA-----REQIDAVITLDVPHSVIIDRVKNRwihapsgrvynigfknpkvpgkddvtgeplmQRE 160
Cdd:PRK02496  83 ILDGFPRKVTQAAFLDEllqeiGQSGERVVNLDVPDDVVVERLLAR-------------------------------GRK 131

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 24645822  161 DDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQTKE 201
Cdd:PRK02496 132 DDTEEVIRRRLEVYREQTAPLIDYYRDRQKLLTIDGNQSVE 172
PRK14531 PRK14531
adenylate kinase; Provisional
 7-201 9.83e-38

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 129.55  E-value: 9.83e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    7 RAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVGNRSYI 86
Cdd:PRK14531   4 RLLFLGPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSALGQEAEAVMNRGELVSDALVLAIVESQLKALNSGGWL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   87 LDGFPRNIAQAEALAA-----REQIDAVITLDVPHSVIIDRVKNRwihapsgrvynigfknpkvpgkddvtgeplmQRED 161
Cdd:PRK14531  84 LDGFPRTVAQAEALEPlleelKQPIEAVVLLELDDAVLIERLLAR-------------------------------GRAD 132

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 24645822  162 DKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQTKE 201
Cdd:PRK14531 133 DNEAVIRNRLEVYREKTAPLIDHYRQRGLLQSVEAQGSIE 172
PLN02459 PLN02459
probable adenylate kinase
 9-194 5.47e-37

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 129.58  E-value: 5.47e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    9 VIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTM---LARITEVGNRSY 85
Cdd:PLN02459  33 VFLGCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLskrLEAGEEEGESGF 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   86 ILDGFPRNIAQAEALAAREQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPK-VPGKDDVTGEPLM------- 157
Cdd:PLN02459 113 ILDGFPRTVRQAEILEGVTDIDLVVNLKLREEVLVEKCLGRRICSECGKNFNVADIDLKgEDGRPGIVMPPLLpppecas 192

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 24645822  158 ---QREDDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATF 194
Cdd:PLN02459 193 kliTRADDTEEVVKARLRVYKEESQPVEDFYRKRGKLLEF 232
PRK14526 PRK14526
adenylate kinase; Provisional
 9-187 2.03e-36

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 126.89  E-value: 2.03e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    9 VIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVGNR-SYIL 87
Cdd:PRK14526   4 VFLGPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKEIKQIVENGQLVPDSITIKIVEDKINTIKNNdNFIL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   88 DGFPRNIAQAEALAAREQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQREDDKPHVV 167
Cdd:PRK14526  84 DGFPRNINQAKALDKFLPNIKIINFLIDEELLIKRLSGRRICKSCNNIFNIYTLPTKEKGICDVCKGDLYQRKDDKEESL 163

                        170       180
                 ....*....|....*....|
gi 24645822  168 AKRLELYDEVMSPVIAWYEK 187
Cdd:PRK14526 164 KTRLQEYKLQTKPLIEFYSK 183
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 7-189 1.73e-35

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 124.91  E-value: 1.73e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    7 RAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVGN---R 83
Cdd:PTZ00088   8 KIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIVKDEIAKVTDdcfK 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   84 SYILDGFPRNIAQAEALAAREQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKN-------PKVPGKDDVT--GE 154
Cdd:PTZ00088  88 GFILDGFPRNLKQCKELGKITNIDLFVNIYLPRNILIKKLLGRRICNTCNRNFNIAHIRsdpydmpPILPPADCEGckGN 167

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 24645822  155 P-LMQREDDKPHVVAKRLELYDEVMSPVIAWYEKKG 189
Cdd:PTZ00088 168 PkLQKRSDDTEEIVAHRLNTYESTNSPIIQFFKNEN 203
PRK14532 PRK14532
adenylate kinase; Provisional
 9-201 3.68e-34

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 120.31  E-value: 3.68e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    9 VIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEV-GNRSYIL 87
Cdd:PRK14532   4 ILFGPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIEERLPEAeAAGGAIF 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   88 DGFPRNIAQAEA----LAAREQ-IDAVITLDVPHSVIIDRVKNRWihAPSGrvynigfknpkvpgkddvtgeplmqREDD 162
Cdd:PRK14532  84 DGFPRTVAQAEAldkmLASRGQkIDVVIRLKVDDEALIERIVKRF--EEQG-------------------------RPDD 136

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 24645822  163 KPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQTKE 201
Cdd:PRK14532 137 NPEVFVTRLDAYNAQTAPLLPYYAGQGKLTEVDGMGSIE 175
PRK14527 PRK14527
adenylate kinase; Provisional
 7-196 4.59e-33

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 117.58  E-value: 4.59e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    7 RAVI-IGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVGNRSY 85
Cdd:PRK14527   7 KVVIfLGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRDELAGMEPVRV 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   86 ILDGFPRNIAQAEAL-------AAReqIDAVITLDVPHSVIIDRVKNRWIHApsgrvynigfknpkvpgkddvtgeplmQ 158
Cdd:PRK14527  87 IFDGFPRTLAQAEALdrlleelGAR--LLAVVLLEVPDEELIRRIVERARQE---------------------------G 137

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 24645822  159 REDDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKG 196
Cdd:PRK14527 138 RSDDNEETVRRRQQVYREQTQPLVDYYEARGHLKRVDG 175
PRK13808 PRK13808
adenylate kinase; Provisional
 7-202 9.88e-32

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 117.68  E-value: 9.88e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    7 RAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEV-GNRSY 85
Cdd:PRK13808   2 RLILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPVGLKAKDIMASGGLVPDEVVVGIISDRIEQPdAANGF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   86 ILDGFPRNIAQAEALAA-----REQIDAVITLDVPHSVIIDRVKNRwIHAPSGRvynigfknpkvpgkddvtGEPLmqRE 160
Cdd:PRK13808  82 ILDGFPRTVPQAEALDAllkdkQLKLDAVVELRVNEGALLARVETR-VAEMRAR------------------GEEV--RA 140

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 24645822  161 DDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKG-----KQTKEI 202
Cdd:PRK13808 141 DDTPEVLAKRLASYRAQTEPLVHYYSEKRKLLTVDGmmtidEVTREI 187
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 10-202 1.42e-29

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 108.23  E-value: 1.42e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    10 IIGAPGSGKGTISELICKNHGCVHISTGDILRQNI-IKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVG-NRSYIL 87
Cdd:TIGR01359   4 VLGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIkREGSENGSLIESYIKEGKIVPSEVTVELLKKAIQEDGsSKKFLI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    88 DGFPRNiaqAEALAAREQ-------IDAVITLDVPHSVIIDRVKNRwiHAPSGRVynigfknpkvpgkddvtgeplmqre 160
Cdd:TIGR01359  84 DGFPRN---EENLEAWEKlmdnkvnFKFVLFFDCPEETMIKRLLKR--GQTSGRV------------------------- 133

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 24645822   161 DDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQTKEI 202
Cdd:TIGR01359 134 DDNIETLKKRFRTYNEETLPIIEHFENKGKVKEINAEGSVEE 175
PRK14528 PRK14528
adenylate kinase; Provisional
 7-201 1.92e-29

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 108.18  E-value: 1.92e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    7 RAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVGNRS-Y 85
Cdd:PRK14528   3 NIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKDRIREADCKNgF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   86 ILDGFPRNIAQAEALAA-----REQIDAVITLDVPHSVIIDRVKNRWIhapsgrvynigfknpkvpgkddvtgepLMQRE 160
Cdd:PRK14528  83 LLDGFPRTVEQADALDAllkneGKSIDKAINLEVPDGELLKRLLGRAE---------------------------IEGRA 135

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 24645822  161 DDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQTKE 201
Cdd:PRK14528 136 DDNEATIKNRLDNYNKKTLPLLDFYAAQKKLSQVNGVGSLE 176
PRK14529 PRK14529
adenylate kinase; Provisional
 9-197 7.29e-29

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 107.50  E-value: 7.29e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    9 VIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVGNRSYILD 88
Cdd:PRK14529   4 LIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKKAKEYIDRGDLVPDDITIPMILETLKQDGKNGWLLD 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   89 GFPRNIAQAEALAAREQ-----IDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDD--VTGEPLMQRED 161
Cdd:PRK14529  84 GFPRNKVQAEKLWEALQkegmkLDYVIEILLPREVAKNRIMGRRLCKNDNNHPNNIFIDAIKPDGDVcrVCGGELSTRAD 163

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 24645822  162 DKPH-VVAKRLEL-YDEVMSPVIAWYEKKGLVATFKGK 197
Cdd:PRK14529 164 DQDEeAINKRHDIyYDTETGTLAAAYFFKDLAAKGSTK 201
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 10-201 4.49e-27

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 102.20  E-value: 4.49e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    10 IIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIV----TKTMLARITEvgNRSY 85
Cdd:TIGR01360   8 IVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVldllKDAMVAALGT--SKGF 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    86 ILDGFPRNIAQAEALAAR-EQIDAVITLDVPHSVIIDRVKNRwiHAPSGRVynigfknpkvpgkddvtgeplmqreDDKP 164
Cdd:TIGR01360  86 LIDGYPREVKQGEEFERRiGPPTLVLYFDCSEDTMVKRLLKR--AETSGRV-------------------------DDNE 138

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 24645822   165 HVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQTKE 201
Cdd:TIGR01360 139 KTIKKRLETYYKATEPVIAYYETKGKLRKINAEGTVD 175
PLN02200 PLN02200
adenylate kinase family protein
 6-189 3.51e-23

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 93.03  E-value: 3.51e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    6 FRAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVGNRSY 85
Cdd:PLN02200  44 FITFVLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEHGAMILNTIKEGKIVPSEVTVKLIQKEMESSDNNKF 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   86 ILDGFPRNiaqAEALAAREQI-----DAVITLDVPHSVIIDRVKNRwihaPSGRVynigfknpkvpgkddvtgeplmqre 160
Cdd:PLN02200 124 LIDGFPRT---EENRIAFERIigaepNVVLFFDCPEEEMVKRVLNR----NQGRV------------------------- 171

                        170       180
                 ....*....|....*....|....*....
gi 24645822  161 DDKPHVVAKRLELYDEVMSPVIAWYEKKG 189
Cdd:PLN02200 172 DDNIDTIKKRLKVFNALNLPVIDYYSKKG 200
AAA_17 pfam13207
AAA domain;
12-136 8.58e-23

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 89.22  E-value: 8.58e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    12 GAPGSGKGTISELICKNHGCVHISTGDILRQnIIKNTELGkKAKQYIAEGKLVPDAIVTKTMLARITE-VGNRSYILDGF 90
Cdd:pfam13207   2 GVPGSGKTTQLKKLAEKLGFPHISAGDLLRE-EAKERGLV-EDRDEMRKLPLEPQKELQKLAAERIAEeAGEGGVIVDGH 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 24645822    91 PRNIAQAEALAAREQ-------IDAVITLDVPHSVIIDRVKNRwihAPSGRVY 136
Cdd:pfam13207  80 PRIKTPAGYLPGLPVevlrelkPDAIILLEADPEEILERRLKD---RTRGRDD 129
ADK_lid pfam05191
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular ...
 126-161 5.64e-15

Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organizms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function.


Pssm-ID: 461578 [Multi-domain]  Cd Length: 36  Bit Score: 65.95  E-value: 5.64e-15
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 24645822   126 RWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQRED 161
Cdd:pfam05191   1 RRVCPKCGRIYHVYFNPPKVEGVCDVCGGELVQRDD 36
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 9-126 5.73e-09

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 52.70  E-value: 5.73e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822     9 VIIGAPGSGKGTISELICKNHGCVHISTGDILRQniIKNTELGKKAKqYIAEGKLVPDAIVTktmLARITEVGNRSYILD 88
Cdd:pfam13671   3 LLVGLPGSGKSTLARRLLEELGAVRLSSDDERKR--LFGEGRPSISY-YTDATDRTYERLHE---LARIALRAGRPVILD 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 24645822    89 -GFPRNIAQAEALAAREQIDA---VITLDVPHSVIIDRVKNR 126
Cdd:pfam13671  77 aTNLRRDERARLLALAREYGVpvrIVVFEAPEEVLRERLAAR 118
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
9-126 3.02e-07

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 48.37  E-value: 3.02e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822   9 VIIGAPGSGKGTISELICKNHGCVHISTgDILRQNIikntelgkkAKQYIAEGKLVPDA--IVTKTMLARITEV--GNRS 84
Cdd:COG0645   3 LVCGLPGSGKSTLARALAERLGAVRLRS-DVVRKRL---------FGAGLAPLERSPEAtaRTYARLLALARELlaAGRS 72

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 24645822  85 YILD-GFPRNI--AQAEALAAREQID-AVITLDVPHSVIIDRVKNR 126
Cdd:COG0645  73 VILDaTFLRRAqrEAFRALAEEAGAPfVLIWLDAPEEVLRERLEAR 118
AAA_18 pfam13238
AAA domain;
9-126 5.03e-05

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 41.65  E-value: 5.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822     9 VIIGAPGSGKGTISELICKNHGCVHIStGDILRQNIIKNTELGKKAKQYIA-EGKlvpDAIVTKTMLARITEVGNRSYIL 87
Cdd:pfam13238   2 LITGTPGVGKTTLAKELSKRLGFGDNV-RDLALENGLVLGDDPETRESKRLdEDK---LDRLLDLLEENAALEEGGNLII 77

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 24645822    88 DGFPrniaqAEALAAREQIDAVITLDVPHSVIIDRVKNR 126
Cdd:pfam13238  78 DGHL-----AELEPERAKDLVGIVLRASPEELLERLEKR 111
PRK04182 PRK04182
cytidylate kinase; Provisional
 9-42 8.00e-05

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 41.72  E-value: 8.00e-05
                         10        20        30
                 ....*....|....*....|....*....|....
gi 24645822    9 VIIGAPGSGKGTISELICKNHGCVHISTGDILRQ 42
Cdd:PRK04182   4 TISGPPGSGKTTVARLLAEKLGLKHVSAGEIFRE 37
cyt_kin_arch TIGR02173
cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. ...
 9-42 5.50e-04

cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. Members of this family are found in the archaea and in spirochaetes, and differ considerably from the common bacterial form of cytidylate kinase described by TIGR00017.


Pssm-ID: 274012 [Multi-domain]  Cd Length: 171  Bit Score: 39.33  E-value: 5.50e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 24645822     9 VIIGAPGSGKGTISELICKNHGCVHISTGDILRQ 42
Cdd:TIGR02173   4 TISGPPGSGKTTVAKILAEKLSLKLISAGDIFRE 37
PRK01184 PRK01184
flagellar hook-basal body complex protein FliE;
9-126 1.40e-03

flagellar hook-basal body complex protein FliE;


Pssm-ID: 234914 [Multi-domain]  Cd Length: 184  Bit Score: 38.00  E-value: 1.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822    9 VIIGAPGSGKGTISElICKNHGCVHISTGDILRQNIIKN------TELGKKAKQYIAEgkLVPDAIVTKTmLARITEVGN 82
Cdd:PRK01184   5 GVVGMPGSGKGEFSK-IAREMGIPVVVMGDVIREEVKKRgleptdENIGKVAIDLRKE--LGMDAVAKRT-VPKIREKGD 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 24645822   83 RSYILDGFpRNIAQAEALaaREQIDA---VITLDVPHSVIIDRVKNR 126
Cdd:PRK01184  81 EVVVIDGV-RGDAEVEYF--RKEFPEdfiLIAIHAPPEVRFERLKKR 124
COG3911 COG3911
Predicted ATPase [General function prediction only];
1-42 6.87e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443117  Cd Length: 180  Bit Score: 35.95  E-value: 6.87e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....
gi 24645822   1 MFTKIFraVIIGAPGSGKGT-ISELICKNHGCVH-ISTGDILRQ 42
Cdd:COG3911   1 MMTRRI--VITGGPGSGKTTlLNALARRGYACVPeAGREIIREQ 42
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 10-89 8.06e-03

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 35.54  E-value: 8.06e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645822  10 IIGAPGSGKGTISELICKNHGCVHISTGDilrqniIKNTELGKKAKQYIAegklVPDaiVTKTMLARITEVG-NRSYILD 88
Cdd:cd02020   4 IDGPAGSGKSTVAKLLAKKLGLPYLDTGG------IRTEEVGKLASEVAA----IPE--VRKALDERQRELAkKPGIVLE 71


                .
gi 24645822  89 G 89
Cdd:cd02020  72 G 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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