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Conserved domains on  [gi|24647534|ref|NP_732176|]
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abdominal A, isoform B [Drosophila melanogaster]

Protein Classification

homeodomain and Abdominal-A domain-containing protein( domain architecture ID 11079060)

homeodomain and Abdominal-A domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
399-455 2.75e-27

Homeodomain;


:

Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 104.12  E-value: 2.75e-27
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 24647534   399 RRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKK 455
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
Abdominal-A pfam12407
Homeobox protein; This domain family is found in eukaryotes, and is approximately 30 amino ...
 456-478 4.08e-09

Homeobox protein; This domain family is found in eukaryotes, and is approximately 30 amino acids in length. The family is found in association with pfam00046. This family is a homeobox protein involved in differentiation of embryonic cells to form the abdominal region.


:

Pssm-ID: 403567  Cd Length: 24  Bit Score: 52.10  E-value: 4.08e-09
                          10        20
                  ....*....|....*....|...
gi 24647534   456 ELRAVKEINEQARRDREEQEKMK 478
Cdd:pfam12407   1 ELRAVKEINEQARRERDEQAKKK 23
 
Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
399-455 2.75e-27

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 104.12  E-value: 2.75e-27
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 24647534   399 RRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKK 455
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 399-456 4.16e-23

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 92.69  E-value: 4.16e-23
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 24647534 399 RRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKE 456
Cdd:cd00086   1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRS 58
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 398-454 4.17e-23

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 92.31  E-value: 4.17e-23
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 24647534    398 RRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLK 454
Cdd:smart00389   1 KRRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
397-478 1.80e-11

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 62.45  E-value: 1.80e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647534 397 PRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEineqARRDREEQEK 476
Cdd:COG5576  50 PPKSKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAKEKKKRSGKVE----QRPGEEEADL 125


                ..
gi 24647534 477 MK 478
Cdd:COG5576 126 AK 127
Abdominal-A pfam12407
Homeobox protein; This domain family is found in eukaryotes, and is approximately 30 amino ...
 456-478 4.08e-09

Homeobox protein; This domain family is found in eukaryotes, and is approximately 30 amino acids in length. The family is found in association with pfam00046. This family is a homeobox protein involved in differentiation of embryonic cells to form the abdominal region.


Pssm-ID: 403567  Cd Length: 24  Bit Score: 52.10  E-value: 4.08e-09
                          10        20
                  ....*....|....*....|...
gi 24647534   456 ELRAVKEINEQARRDREEQEKMK 478
Cdd:pfam12407   1 ELRAVKEINEQARRERDEQAKKK 23
 
Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
399-455 2.75e-27

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 104.12  E-value: 2.75e-27
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 24647534   399 RRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKK 455
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 399-456 4.16e-23

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 92.69  E-value: 4.16e-23
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 24647534 399 RRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKE 456
Cdd:cd00086   1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRS 58
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 398-454 4.17e-23

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 92.31  E-value: 4.17e-23
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 24647534    398 RRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLK 454
Cdd:smart00389   1 KRRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
397-478 1.80e-11

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 62.45  E-value: 1.80e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647534 397 PRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEineqARRDREEQEK 476
Cdd:COG5576  50 PPKSKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAKEKKKRSGKVE----QRPGEEEADL 125


                ..
gi 24647534 477 MK 478
Cdd:COG5576 126 AK 127
Abdominal-A pfam12407
Homeobox protein; This domain family is found in eukaryotes, and is approximately 30 amino ...
 456-478 4.08e-09

Homeobox protein; This domain family is found in eukaryotes, and is approximately 30 amino acids in length. The family is found in association with pfam00046. This family is a homeobox protein involved in differentiation of embryonic cells to form the abdominal region.


Pssm-ID: 403567  Cd Length: 24  Bit Score: 52.10  E-value: 4.08e-09
                          10        20
                  ....*....|....*....|...
gi 24647534   456 ELRAVKEINEQARRDREEQEKMK 478
Cdd:pfam12407   1 ELRAVKEINEQARRERDEQAKKK 23
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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