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Conserved domains on  [gi|221379662|ref|NP_732208|]
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cheerio, isoform H [Drosophila melanogaster]

Protein Classification

IG_FLMN and Filamin domain-containing protein( domain architecture ID 12215647)

IG_FLMN and Filamin domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 452-540 7.92e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 116.16  E-value: 7.92e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662   452 HLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPS--KADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHI 529
Cdd:smart00557   2 SKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHI 81

                           90
                   ....*....|.
gi 221379662   530 PDSPFKVYVSP 540
Cdd:smart00557  82 PGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 258-347 3.30e-30

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 114.62  E-value: 3.30e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662   258 AKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPS--KAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHH 335
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 221379662   336 VEGSPFTVKVAG 347
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 77-164 3.47e-29

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.54  E-value: 3.47e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662    77 YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPS--KADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIK 154
Cdd:smart00557   3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82

                           90
                   ....*....|
gi 221379662   155 GSPYFAKITG 164
Cdd:smart00557  83 GSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 640-728 1.33e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 95.75  E-value: 1.33e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662   640 PAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAVSIDGPS--KVAMDCTEVEEG-YKVRYTPLLPGEHYITVKYNNMH 716
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGtYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 221379662   717 IVGSPFKVNATG 728
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 768-857 3.48e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 94.59  E-value: 3.48e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662   768 ASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGEEH 847
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|
gi 221379662   848 IPGSPFQIDV 857
Cdd:smart00557  81 IPGSPFTVKV 90
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 545-634 3.39e-19

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 83.04  E-value: 3.39e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662   545 AHKLEVQQFPQGNIQADAPYQFMVRKNGA-KGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVH 623
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|.
gi 221379662   624 IPDSPFRIKVG 634
Cdd:smart00557  81 IPGSPFTVKVG 91
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 6-71 2.63e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 74.95  E-value: 2.63e-16
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 221379662     6 KSSFSIVTHQA-------EVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVD 71
Cdd:smart00557  19 PAEFTVDTRDAgggelevEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91
Filamin pfam00630
Filamin/ABP280 repeat;
391-439 2.48e-11

Filamin/ABP280 repeat;


:

Pssm-ID: 395505  Cd Length: 89  Bit Score: 60.38  E-value: 2.48e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 221379662  391 VTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPF 439
Cdd:pfam00630  40 VTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
 
Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 452-540 7.92e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 116.16  E-value: 7.92e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662   452 HLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPS--KADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHI 529
Cdd:smart00557   2 SKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHI 81

                           90
                   ....*....|.
gi 221379662   530 PDSPFKVYVSP 540
Cdd:smart00557  82 PGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 258-347 3.30e-30

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 114.62  E-value: 3.30e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662   258 AKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPS--KAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHH 335
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 221379662   336 VEGSPFTVKVAG 347
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 77-164 3.47e-29

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.54  E-value: 3.47e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662    77 YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPS--KADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIK 154
Cdd:smart00557   3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82

                           90
                   ....*....|
gi 221379662   155 GSPYFAKITG 164
Cdd:smart00557  83 GSPFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
255-342 5.82e-24

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 96.59  E-value: 5.82e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662  255 VGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGfGGLSVSIEGPS--KAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFA 332
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                          90
                  ....*....|
gi 221379662  333 DHHVEGSPFT 342
Cdd:pfam00630  80 GQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 640-728 1.33e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 95.75  E-value: 1.33e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662   640 PAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAVSIDGPS--KVAMDCTEVEEG-YKVRYTPLLPGEHYITVKYNNMH 716
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGtYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 221379662   717 IVGSPFKVNATG 728
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 768-857 3.48e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 94.59  E-value: 3.48e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662   768 ASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGEEH 847
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|
gi 221379662   848 IPGSPFQIDV 857
Cdd:smart00557  81 IPGSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
454-535 4.59e-22

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 91.20  E-value: 4.59e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662  454 VKAGGSGLERGVVGEAAEFNVWTREAGGGsLAISVEGPS--KADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPD 531
Cdd:pfam00630   7 VKASGPGLEPGVVGKPAEFTVDTRDAGGE-GEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85


                  ....
gi 221379662  532 SPFK 535
Cdd:pfam00630  86 SPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
78-158 5.81e-21

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 88.11  E-value: 5.81e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662   78 VTAYGPGLTHGVTGEPANFTISTKGASaGGLTMAVEGPS--KADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKG 155
Cdd:pfam00630   7 VKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85


                  ...
gi 221379662  156 SPY 158
Cdd:pfam00630  86 SPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 545-634 3.39e-19

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 83.04  E-value: 3.39e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662   545 AHKLEVQQFPQGNIQADAPYQFMVRKNGA-KGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVH 623
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|.
gi 221379662   624 IPDSPFRIKVG 634
Cdd:smart00557  81 IPGSPFTVKVG 91
Filamin pfam00630
Filamin/ABP280 repeat;
637-723 8.23e-19

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 81.95  E-value: 8.23e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662  637 VADPAAVHASGNGLDEVKTGHKADFIINTCNAGvGTLAVSIDGPS--KVAMDCTEVEEG-YKVRYTPLLPGEHYITVKYN 713
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGtYTVSYTPTEPGDYTVSVKFN 79

                          90
                  ....*....|
gi 221379662  714 NMHIVGSPFK 723
Cdd:pfam00630  80 GQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 6-71 2.63e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 74.95  E-value: 2.63e-16
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 221379662     6 KSSFSIVTHQA-------EVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVD 71
Cdd:smart00557  19 PAEFTVDTRDAgggelevEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91
Filamin pfam00630
Filamin/ABP280 repeat;
542-630 2.74e-15

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 71.94  E-value: 2.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662  542 AGDAHKLEVQQFPQGNIQADAPYQFMVRKNGAKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNG 621
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*....
gi 221379662  622 VHIPDSPFR 630
Cdd:pfam00630  81 QHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
766-853 1.41e-14

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 69.63  E-value: 1.41e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662  766 SDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILyVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGE 845
Cdd:pfam00630   2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGEGE-VEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*...
gi 221379662  846 EHIPGSPF 853
Cdd:pfam00630  81 QHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
2-67 3.30e-12

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 63.08  E-value: 3.30e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 221379662    2 PLNFKSSFSIVTHQA------EVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFK 67
Cdd:pfam00630  18 VVGKPAEFTVDTRDAggegevEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
391-439 2.48e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 60.38  E-value: 2.48e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 221379662  391 VTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPF 439
Cdd:pfam00630  40 VTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
 
Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 452-540 7.92e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 116.16  E-value: 7.92e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662   452 HLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPS--KADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHI 529
Cdd:smart00557   2 SKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHI 81

                           90
                   ....*....|.
gi 221379662   530 PDSPFKVYVSP 540
Cdd:smart00557  82 PGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 258-347 3.30e-30

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 114.62  E-value: 3.30e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662   258 AKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPS--KAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHH 335
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 221379662   336 VEGSPFTVKVAG 347
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 77-164 3.47e-29

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.54  E-value: 3.47e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662    77 YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPS--KADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIK 154
Cdd:smart00557   3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82

                           90
                   ....*....|
gi 221379662   155 GSPYFAKITG 164
Cdd:smart00557  83 GSPFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
255-342 5.82e-24

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 96.59  E-value: 5.82e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662  255 VGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGfGGLSVSIEGPS--KAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFA 332
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                          90
                  ....*....|
gi 221379662  333 DHHVEGSPFT 342
Cdd:pfam00630  80 GQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 640-728 1.33e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 95.75  E-value: 1.33e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662   640 PAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAVSIDGPS--KVAMDCTEVEEG-YKVRYTPLLPGEHYITVKYNNMH 716
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGtYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 221379662   717 IVGSPFKVNATG 728
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 768-857 3.48e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 94.59  E-value: 3.48e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662   768 ASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGEEH 847
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|
gi 221379662   848 IPGSPFQIDV 857
Cdd:smart00557  81 IPGSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
454-535 4.59e-22

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 91.20  E-value: 4.59e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662  454 VKAGGSGLERGVVGEAAEFNVWTREAGGGsLAISVEGPS--KADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPD 531
Cdd:pfam00630   7 VKASGPGLEPGVVGKPAEFTVDTRDAGGE-GEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85


                  ....
gi 221379662  532 SPFK 535
Cdd:pfam00630  86 SPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
78-158 5.81e-21

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 88.11  E-value: 5.81e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662   78 VTAYGPGLTHGVTGEPANFTISTKGASaGGLTMAVEGPS--KADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKG 155
Cdd:pfam00630   7 VKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85


                  ...
gi 221379662  156 SPY 158
Cdd:pfam00630  86 SPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 545-634 3.39e-19

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 83.04  E-value: 3.39e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662   545 AHKLEVQQFPQGNIQADAPYQFMVRKNGA-KGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVH 623
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|.
gi 221379662   624 IPDSPFRIKVG 634
Cdd:smart00557  81 IPGSPFTVKVG 91
Filamin pfam00630
Filamin/ABP280 repeat;
637-723 8.23e-19

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 81.95  E-value: 8.23e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662  637 VADPAAVHASGNGLDEVKTGHKADFIINTCNAGvGTLAVSIDGPS--KVAMDCTEVEEG-YKVRYTPLLPGEHYITVKYN 713
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGtYTVSYTPTEPGDYTVSVKFN 79

                          90
                  ....*....|
gi 221379662  714 NMHIVGSPFK 723
Cdd:pfam00630  80 GQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 6-71 2.63e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 74.95  E-value: 2.63e-16
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 221379662     6 KSSFSIVTHQA-------EVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVD 71
Cdd:smart00557  19 PAEFTVDTRDAgggelevEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91
Filamin pfam00630
Filamin/ABP280 repeat;
542-630 2.74e-15

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 71.94  E-value: 2.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662  542 AGDAHKLEVQQFPQGNIQADAPYQFMVRKNGAKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNG 621
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*....
gi 221379662  622 VHIPDSPFR 630
Cdd:pfam00630  81 QHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
766-853 1.41e-14

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 69.63  E-value: 1.41e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221379662  766 SDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILyVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGE 845
Cdd:pfam00630   2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGEGE-VEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*...
gi 221379662  846 EHIPGSPF 853
Cdd:pfam00630  81 QHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
2-67 3.30e-12

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 63.08  E-value: 3.30e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 221379662    2 PLNFKSSFSIVTHQA------EVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFK 67
Cdd:pfam00630  18 VVGKPAEFTVDTRDAggegevEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
391-439 2.48e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 60.38  E-value: 2.48e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 221379662  391 VTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPF 439
Cdd:pfam00630  40 VTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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