NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|25150003|ref|NP_741577|]
View 

Autophagy-related protein 18 [Caenorhabditis elegans]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 11455410)

WD40 repeat domain-containing protein similar to proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
PubMed:  10322433|8090199
SCOP:  4002744

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
69-264 1.21e-12

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 68.78  E-value: 1.21e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003  69 FSSALMVVISQKDPRVLHVYHF-TSRNIICDHRFNKSVLTVRLNRD--RIVVCLEDC-IYIYNLKDMKMMHNImdtPTNK 144
Cdd:COG2319  86 FSPDGRLLASASADGTVRLWDLaTGLLLRTLTGHTGAVRSVAFSPDgkTLASGSADGtVRLWDLATGKLLRTL---TGHS 162

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003 145 LGVLDLTSNPGNALIAYpGSTDtGSVHLFDAINLSSVSTFNAHEGTIACLKFNQEGNMIATASTKGTViRVYSVPNGHRL 224
Cdd:COG2319 163 GAVTSVAFSPDGKLLAS-GSDD-GTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTV-RLWDLATGKLL 239

                       170       180       190       200
                ....*....|....*....|....*....|....*....|
gi 25150003 225 FEFRRGVTRcvnIYSLCFSSDSKYLTSSSNTETVHVFKLE 264
Cdd:COG2319 240 RTLTGHSGS---VRSVAFSPDGRLLASGSADGTVRLWDLA 276
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
69-264 1.21e-12

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 68.78  E-value: 1.21e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003  69 FSSALMVVISQKDPRVLHVYHF-TSRNIICDHRFNKSVLTVRLNRD--RIVVCLEDC-IYIYNLKDMKMMHNImdtPTNK 144
Cdd:COG2319  86 FSPDGRLLASASADGTVRLWDLaTGLLLRTLTGHTGAVRSVAFSPDgkTLASGSADGtVRLWDLATGKLLRTL---TGHS 162

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003 145 LGVLDLTSNPGNALIAYpGSTDtGSVHLFDAINLSSVSTFNAHEGTIACLKFNQEGNMIATASTKGTViRVYSVPNGHRL 224
Cdd:COG2319 163 GAVTSVAFSPDGKLLAS-GSDD-GTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTV-RLWDLATGKLL 239

                       170       180       190       200
                ....*....|....*....|....*....|....*....|
gi 25150003 225 FEFRRGVTRcvnIYSLCFSSDSKYLTSSSNTETVHVFKLE 264
Cdd:COG2319 240 RTLTGHSGS---VRSVAFSPDGRLLASGSADGTVRLWDLA 276
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 18-267 1.51e-11

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 64.66  E-value: 1.51e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003  18 FNQDSKVICVGHKDGymfykTADI--LENNTLTYEGENLTHlGLNNCLII---ERLFSSAL--MVVI-SQKDPRVLHVYH 89
Cdd:cd00200  17 FSPDGKLLATGSGDG-----TIKVwdLETGELLRTLKGHTG-PVRDVAASadgTYLASGSSdkTIRLwDLETGECVRTLT 90

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003  90 ftsrniicDHrfNKSVLTVRLNRDR--IVVCLED-CIYIYNLKDMKmmhNIMDTPTNKLGVLDLTSNPGNALIAypGSTD 166
Cdd:cd00200  91 --------GH--TSYVSSVAFSPDGriLSSSSRDkTIKVWDVETGK---CLTTLRGHTDWVNSVAFSPDGTFVA--SSSQ 155

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003 167 TGSVHLFDAINLSSVSTFNAHEGTIACLKFNQEGNMIATASTKGTvIRVYSVPNG---HRLFEFRRGVtrcvniYSLCFS 243
Cdd:cd00200 156 DGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGT-IKLWDLSTGkclGTLRGHENGV------NSVAFS 228

                       250       260
                ....*....|....*....|....
gi 25150003 244 SDSKYLTSSSNTETVHVFKLEKTE 267
Cdd:cd00200 229 PDGYLLASGSEDGTIRVWDLRTGE 252
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 177-217 2.15e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 38.45  E-value: 2.15e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 25150003    177 NLSSVSTFNAHEGTIACLKFNQEGNMIATASTKGTvIRVYS 217
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGT-IKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
179-217 1.10e-03

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 36.55  E-value: 1.10e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 25150003   179 SSVSTFNAHEGTIACLKFNQEGNMIATASTKGTvIRVYS 217
Cdd:pfam00400   2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGT-VKVWD 39
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
69-264 1.21e-12

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 68.78  E-value: 1.21e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003  69 FSSALMVVISQKDPRVLHVYHF-TSRNIICDHRFNKSVLTVRLNRD--RIVVCLEDC-IYIYNLKDMKMMHNImdtPTNK 144
Cdd:COG2319  86 FSPDGRLLASASADGTVRLWDLaTGLLLRTLTGHTGAVRSVAFSPDgkTLASGSADGtVRLWDLATGKLLRTL---TGHS 162

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003 145 LGVLDLTSNPGNALIAYpGSTDtGSVHLFDAINLSSVSTFNAHEGTIACLKFNQEGNMIATASTKGTViRVYSVPNGHRL 224
Cdd:COG2319 163 GAVTSVAFSPDGKLLAS-GSDD-GTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTV-RLWDLATGKLL 239

                       170       180       190       200
                ....*....|....*....|....*....|....*....|
gi 25150003 225 FEFRRGVTRcvnIYSLCFSSDSKYLTSSSNTETVHVFKLE 264
Cdd:COG2319 240 RTLTGHSGS---VRSVAFSPDGRLLASGSADGTVRLWDLA 276
WD40 COG2319
WD40 repeat [General function prediction only];
155-267 2.60e-12

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 67.63  E-value: 2.60e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003 155 GNALIAypGSTDtGSVHLFDAINLSSVSTFNAHEGTIACLKFNQEGNMIATASTKGTViRVYSVPNGHRLFEFRrGVTRC 234
Cdd:COG2319 132 GKTLAS--GSAD-GTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTV-RLWDLATGKLLRTLT-GHTGA 206

                        90       100       110
                ....*....|....*....|....*....|...
gi 25150003 235 VNiySLCFSSDSKYLTSSSNTETVHVFKLEKTE 267
Cdd:COG2319 207 VR--SVAFSPDGKLLASGSADGTVRLWDLATGK 237
WD40 COG2319
WD40 repeat [General function prediction only];
104-264 1.47e-11

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 65.32  E-value: 1.47e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003 104 SVLTVRLNRD--RIVVCLEDC-IYIYNLKDMKMMHnIMDTPTNklGVLDLTSNPGNALIAYpGSTDtGSVHLFDAINLSS 180
Cdd:COG2319 248 SVRSVAFSPDgrLLASGSADGtVRLWDLATGELLR-TLTGHSG--GVNSVAFSPDGKLLAS-GSDD-GTVRLWDLATGKL 322

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003 181 VSTFNAHEGTIACLKFNQEGNMIATASTKGTViRVYSVPNGHRLFEFrRGVTRcvNIYSLCFSSDSKYLTSSSNTETVHV 260
Cdd:COG2319 323 LRTLTGHTGAVRSVAFSPDGKTLASGSDDGTV-RLWDLATGELLRTL-TGHTG--AVTSVAFSPDGRTLASGSADGTVRL 398


                ....
gi 25150003 261 FKLE 264
Cdd:COG2319 399 WDLA 402
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 18-267 1.51e-11

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 64.66  E-value: 1.51e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003  18 FNQDSKVICVGHKDGymfykTADI--LENNTLTYEGENLTHlGLNNCLII---ERLFSSAL--MVVI-SQKDPRVLHVYH 89
Cdd:cd00200  17 FSPDGKLLATGSGDG-----TIKVwdLETGELLRTLKGHTG-PVRDVAASadgTYLASGSSdkTIRLwDLETGECVRTLT 90

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003  90 ftsrniicDHrfNKSVLTVRLNRDR--IVVCLED-CIYIYNLKDMKmmhNIMDTPTNKLGVLDLTSNPGNALIAypGSTD 166
Cdd:cd00200  91 --------GH--TSYVSSVAFSPDGriLSSSSRDkTIKVWDVETGK---CLTTLRGHTDWVNSVAFSPDGTFVA--SSSQ 155

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003 167 TGSVHLFDAINLSSVSTFNAHEGTIACLKFNQEGNMIATASTKGTvIRVYSVPNG---HRLFEFRRGVtrcvniYSLCFS 243
Cdd:cd00200 156 DGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGT-IKLWDLSTGkclGTLRGHENGV------NSVAFS 228

                       250       260
                ....*....|....*....|....
gi 25150003 244 SDSKYLTSSSNTETVHVFKLEKTE 267
Cdd:cd00200 229 PDGYLLASGSEDGTIRVWDLRTGE 252
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 102-262 1.61e-11

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 64.28  E-value: 1.61e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003 102 NKSVLTVRLNRDRIVV---CLEDCIYIYNLKDMKMMHNIMDtptNKLGVLDLT-SNPGNALIAypGSTDtGSVHLFDAIN 177
Cdd:cd00200 135 TDWVNSVAFSPDGTFVassSQDGTIKLWDLRTGKCVATLTG---HTGEVNSVAfSPDGEKLLS--SSSD-GTIKLWDLST 208

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003 178 LSSVSTFNAHEGTIACLKFNQEGNMIATASTKGTvIRVYSVPNGHRLFEFRRGVTRcvnIYSLCFSSDSKYLTSSSNTET 257
Cdd:cd00200 209 GKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGT-IRVWDLRTGECVQTLSGHTNS---VTSLAWSPDGKRLASGSADGT 284


                ....*
gi 25150003 258 VHVFK 262
Cdd:cd00200 285 IRIWD 289
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 180-267 1.41e-06

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 49.26  E-value: 1.41e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003 180 SVSTFNAHEGTIACLKFNQEGNMIATASTKGTvIRVYSVPNGHRLFEFR---RGVTRCVniyslcFSSDSKYLTSSSNTE 256
Cdd:cd00200   1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGT-IKVWDLETGELLRTLKghtGPVRDVA------ASADGTYLASGSSDK 73

                        90
                ....*....|.
gi 25150003 257 TVHVFKLEKTE 267
Cdd:cd00200  74 TIRLWDLETGE 84
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 11-217 5.67e-06

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 47.71  E-value: 5.67e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003  11 DSINYIGFNQDSKVICVGHKDgymfyKTADILENNTLTYEGENLTHLGLNNCLiierLFSSALMVVISQKDPRVLHVYHF 90
Cdd:cd00200  94 SYVSSVAFSPDGRILSSSSRD-----KTIKVWDVETGKCLTTLRGHTDWVNSV----AFSPDGTFVASSSQDGTIKLWDL 164

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003  91 tsRNIICDHRF---NKSVLTVRL--NRDRIVVCLED-CIYIYNLKDMKMMHNImdtPTNKLGVLDLTSNPGNALIAypGS 164
Cdd:cd00200 165 --RTGKCVATLtghTGEVNSVAFspDGEKLLSSSSDgTIKLWDLSTGKCLGTL---RGHENGVNSVAFSPDGYLLA--SG 237

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|...
gi 25150003 165 TDTGSVHLFDAINLSSVSTFNAHEGTIACLKFNQEGNMIATASTKGTvIRVYS 217
Cdd:cd00200 238 SEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGT-IRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
174-267 1.63e-05

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 46.44  E-value: 1.63e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25150003 174 DAINLSSVSTFNAHEGTIACLKFNQEGNMIATASTKGTViRVYSVPNGHRLFEFRrGVTRcvNIYSLCFSSDSKYLTSSS 253
Cdd:COG2319  64 DAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTV-RLWDLATGLLLRTLT-GHTG--AVRSVAFSPDGKTLASGS 139

                        90
                ....*....|....
gi 25150003 254 NTETVHVFKLEKTE 267
Cdd:COG2319 140 ADGTVRLWDLATGK 153
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 177-217 2.15e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 38.45  E-value: 2.15e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 25150003    177 NLSSVSTFNAHEGTIACLKFNQEGNMIATASTKGTvIRVYS 217
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGT-IKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
179-217 1.10e-03

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 36.55  E-value: 1.10e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 25150003   179 SSVSTFNAHEGTIACLKFNQEGNMIATASTKGTvIRVYS 217
Cdd:pfam00400   2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGT-VKVWD 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH