|
Name |
Accession |
Description |
Interval |
E-value |
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
46-793 |
0e+00 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 1119.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 46 RTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLIYEGYEGMIEGGDFIKEATWNTVSDIIQQGGTIIGSARSSEFRTR 125
Cdd:TIGR02478 1 KRIAVLTSGGDAQGMNAAVRAVVRMAIYVGCRVYAIREGYQGLVDGGDNIEEAQWEDVRGILSLGGTIIGTARCKEFRER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 126 EGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMT 205
Cdd:TIGR02478 81 PGRLKAARNLVSNGIDALVVIGGDGSLTGADLFREEWPSLLEELVDTGKITAEQAEEHRHLTIVGLVGSIDNDMCGTDMT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 206 IGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQ 285
Cdd:TIGR02478 161 IGADSALHRICEAIDAISSTAQSHQRAFVVEVMGRHCGYLALMAAIATGADYVFIPERPPEEGWEDQLCHKLKRNRKAGK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 286 RLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEESEPCV 365
Cdd:TIGR02478 241 RKTIVIVAEGAIDRDLNPITSEDVKDVLVERLGLDTRITVLGHVQRGGAPSAFDRILATRQGVEAVLAVLESTPETPSPV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 366 ISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRGRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAP 445
Cdd:TIGR02478 321 ISLRGNKIVRKPLVEAVAQTKTVAKAIEEKDFDEAMRLRGREFAENLETFLFLSIPDDDKKLVPSEASRLRIAIIHVGAP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 446 AGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPtEKTMPQLAAQLKKHNI 525
Cdd:TIGR02478 401 AGGMNAATRSAVRYALARGHTVIAIHNGFSGLARHDVRELTWSDVEGWVGEGGSELGTNRSLP-GDDLGTIAYYFQQHKI 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 526 QALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKRRVFIV 605
Cdd:TIGR02478 480 DGLIIIGGFEAFEALYQLDAAREKYPAFRIPMVVIPATISNNVPGTEYSLGSDTALNEITEYCDNIKQSASASKRRVFVV 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 606 ETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKK 685
Cdd:TIGR02478 560 ETMGGYSGYLATMAGLATGADAAYIPEEGISLKDLQEDIEHLKETFAEGRAGKLILRNEKASKVYTTDFIARIISEEGKG 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 686 NFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSahTATLLGLKGRKVVFTPV-QDLKK 764
Cdd:TIGR02478 640 RFDARTAVLGHMQQGGSPSPFDRVRATRLAIRAVDFIEEKIKANKHADKLSADDT--SAVVIGIRGSNVLFTPVkQLLAN 717
|
730 740
....*....|....*....|....*....
gi 25147584 765 ETDFEHRLPSEQWWMALRPLLRVLARHRS 793
Cdd:TIGR02478 718 ETDFEHRRPKNQWWLQLRPLVRILAGRDS 746
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
44-792 |
0e+00 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 1027.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 44 KGRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLIYEGYEGMIEGGDFIKEATWNTVSDIIQQGGTIIGSARSSEFR 123
Cdd:cd00764 2 AGKAIAVLTSGGDAQGMNAAVRAVVRMGIYVGAKVFFVYEGYEGLVKGGDYIKQAEWESVSNWLQEGGTIIGSARCKEFR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 124 TREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTD 203
Cdd:cd00764 82 EREGRLQAAYNLIQRGITNLCVIGGDGSLTGADLFRSEWPSLLEELVKDGKITEEEVAKYQHLNIVGMVGSIDNDFCGTD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 204 MTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSE 283
Cdd:cd00764 162 MTIGTDSALHRICEVVDAITTTAQSHQRTFVLEVMGRHCGYLALVSGLATGADWIFIPERPPEDGWEDQMCRRLSEHRSR 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 284 GQRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEESEP 363
Cdd:cd00764 242 GKRLNIIIVAEGAIDDQLKPITSEDVKDLVVERLGLDTRVTTLGHVQRGGTPSAFDRILASLMGVEAVMALLEATPDTPA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 364 CVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRGRSFQRNLETYKLLTKMRTvekDNLSEGHKFNVAVINVG 443
Cdd:cd00764 322 CVVSLNGNKAVRLPLMECVQLTKDVQKAMDEKRFDEAAALRGKSFDKNWNLYKLLAIELP---QPLPEKTNLNIAIVNVG 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 444 APAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPtEKTMPQLAAQLKKH 523
Cdd:cd00764 399 APAAGMNAAVRSAVRYGLAHGHRPYAIYDGFEGLAKGQIVELGWIDVGGWTGRGGSELGTKRTLP-KKDLETIAYNFQKY 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 524 NIQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKRRVF 603
Cdd:cd00764 478 GIDGLIIVGGFEAYKGLLQLREAREQYEEFCIPMVLIPATVSNNVPGTDFSLGSDTALNALMKYCDRIKQSASGTKRRVF 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 604 IVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEG 683
Cdd:cd00764 558 IVETMGGYCGYLATMTGLAVGADAAYVFEEPFNIRDLQENVEHLTEKMKTTIGRGLVLRNEKCNENYTTVFTYELYSEEG 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 684 KKNFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALEFLLIQLKENlTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLK 763
Cdd:cd00764 638 KGVFDCRTNVLGHVQQGGAPSPFDRNFGTKFAVKAMKWIEQKLKEN-YAAGNEFANDPDFNCVNGVKKYAVLFEPVEELK 716
|
730 740
....*....|....*....|....*....
gi 25147584 764 KeTDFEHRLPSEQWWMALRPLLRVLARHR 792
Cdd:cd00764 717 Q-TTFEHRIPKEQWWLSLRPLLKILAKYK 744
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
49-413 |
1.20e-151 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 447.13 E-value: 1.20e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 49 AIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLIYEGYEGMIEGgdFIKEATWNTVSDIIQQGGTIIGSARSSEFRTREGR 128
Cdd:cd00363 4 GVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIYEGYAGLVEG--DIKELDWESVSDIINRGGTIIGSARCKEFRTEEGR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 129 LKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQelvknqrvtaaaakkipYIQIVGLVGSIDNDFCGTDMTIGT 208
Cdd:cd00363 82 AKAAENLKKHGIDALVVIGGDGSYTGADLLTEEWPSKYQ-----------------GFNVIGLPGTIDNDIKGTDYTIGF 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 209 DSALQRIISSIDAVVATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLN 288
Cdd:cd00363 145 DTALKTIVEAIDRIRDTASSHQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAADEWEEEMVDVIKKRRERGKRHG 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 289 IIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEESEPCVISI 368
Cdd:cd00363 225 IVIVAEGAIDFIPKPITEKLLAKLVEERLGFDTRATVLGHVQRGGTPTAFDRILASRLGAEAVELLLEGTGGTPVGIQNL 304
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 25147584 369 DGNVMVRVPLLKCVERTQMVQkamadkdwttaVMLRGRSFQRNLE 413
Cdd:cd00363 305 NENQVVRHPLTEAVNMTKRVG-----------VDLEGRPFKKFAK 338
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
48-351 |
2.64e-135 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 402.10 E-value: 2.64e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 48 LAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLIYEGYEGMIEGgdFIKEATWNTVSDIIQQGGTIIGSARSSEFRTREG 127
Cdd:pfam00365 2 IGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEG--DIDELTWRDVSGILNRGGTILGTSRSKPFKTEEG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 128 RLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTdlvqelvknqrvtaaaakkipyIQIVGLVGSIDNDFCGTDMTIG 207
Cdd:pfam00365 80 REKIAENLKKLGIDALVVIGGDGSLTGANKLSEERG----------------------IPVVGIPKTIDNDIPGTDYTIG 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 208 TDSALQRIISSIDAVVATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPEnwrDVLCDKLSQMRsEGQRL 287
Cdd:pfam00365 138 FDTALNTIVEAIDRIRDTASSHNRVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDI---EELCEKIKELR-KGKRF 213
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 25147584 288 NIIIVAEGAIDrdgkaitAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAV 351
Cdd:pfam00365 214 SIIVVAEGASD-------GEFLAKLIEEGTGIETRVTVLGHVQRGGTPSAFDRILATRLGVKAV 270
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
46-388 |
5.93e-119 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 362.86 E-value: 5.93e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 46 RTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLIYEGYEGMIEGgDFIkEATWNTVSDIIQQGGTIIGSARSSEFRTR 125
Cdd:COG0205 2 KRIGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEG-DII-DLTREDVSGILQRGGTILGSSRSKPFKTE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 126 EGRLKAATNLINRGIGRLVCIGGDGSLTGANTFrlewtdlvqelvknqrvtaAAAKKIPyiqIVGLVGSIDNDFCGTDMT 205
Cdd:COG0205 80 EGREKALENLKKLGIDALVVIGGDGSLDGAAKL-------------------AEEYGIP---VVGIPKTIDNDLPGTDYT 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 206 IGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPEnwrDVLCDKLSQMRSEGQ 285
Cdd:COG0205 138 IGFDTAVNTAAEAIDRLRDTAASHERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDL---DKLLEKLKERRKRGK 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 286 RLNIIIVAEGAIDRDGKAI---------------TAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEA 350
Cdd:COG0205 215 GYSIIVVAEGAGDEDGEAVleadtdafghvrlggIGEYLAKEIEERTGIETRVTVLGHLQRGGSPSAFDRVLASRLGAAA 294
|
330 340 350
....*....|....*....|....*....|....*...
gi 25147584 351 VFALMEmtEESEpCVISIDGNVMVRVPLLKCVERTQMV 388
Cdd:COG0205 295 VELLLE--GKTG-VMVGIRRGEIVLVPLEEVANKEKPV 329
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
46-403 |
8.78e-115 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 351.31 E-value: 8.78e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 46 RTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLIYEGYEGMIEGgDFIKeATWNTVSDIIQQGGTIIGSARSSEFRTR 125
Cdd:PRK03202 2 KRIGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYDGYAGLLEG-DIVK-LDLKSVSDIINRGGTILGSARFPEFKDE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 126 EGRLKAATNLINRGIGRLVCIGGDGSLTGAntfrlewtdlvQELVKNQrvtaaaakkipyIQIVGLVGSIDNDFCGTDMT 205
Cdd:PRK03202 80 EGRAKAIENLKKLGIDALVVIGGDGSYMGA-----------KRLTEHG------------IPVIGLPGTIDNDIAGTDYT 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 206 IGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPenwRDVLCDKLSQMRSEGQ 285
Cdd:PRK03202 137 IGFDTALNTAVEAIDRLRDTASSHERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFD---IEELCAKIKKGRERGK 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 286 RLNIIIVAEGAIDrdgkaitAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEmtEESEPCV 365
Cdd:PRK03202 214 KHAIIVVAEGVMP-------AEELAKEIEERTGLETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLLE--GKGGRMV 284
|
330 340 350
....*....|....*....|....*....|....*....
gi 25147584 366 iSIDGNVMVRVPLLKCVERTqmvqKAMADKDW-TTAVML 403
Cdd:PRK03202 285 -GIQNNKIVHVPIEEAVENM----KHPFDKDLyELAKKL 318
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
436-720 |
1.36e-110 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 338.55 E-value: 1.36e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 436 NVAVINVGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLP--TEKTM 513
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEGDIDELTWRDVSGILNRGGTILGTSRSKPfkTEEGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 514 PQLAAQLKKHNIQALLLVGGFEAYHSTIILAENREkypefcIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQ 593
Cdd:pfam00365 81 EKIAENLKKLGIDALVVIGGDGSLTGANKLSEERG------IPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRD 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 594 SATGTkRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDvilsKMEVGAKRYLVVRNEWADknlTTD 673
Cdd:pfam00365 155 TASSH-NRVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDIEELCEKIK----ELRKGKRFSIIVVAEGAS---DGE 226
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 25147584 674 FVQNLFdsEGKKNFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALE 720
Cdd:pfam00365 227 FLAKLI--EEGTGIETRVTVLGHVQRGGTPSAFDRILATRLGVKAVE 271
|
|
| PFKA_ATP |
TIGR02482 |
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate ... |
48-380 |
4.30e-105 |
|
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate from ATP to fructose 6-phosphate to give fructose 1,6-bisphosphate. This represents a key control step in glycolysis. This model hits bacterial ATP-dependent 6-phosphofructokinases which lack a beta-hairpin loop present in TIGR02483 family members. TIGR02483 contains members that are ATP-dependent as well as members that are pyrophosphate-dependent. TIGR02477 represents the pyrophosphate-dependent phosphofructokinase, diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90). [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213713 [Multi-domain] Cd Length: 301 Bit Score: 325.46 E-value: 4.30e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 48 LAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLIYEGYEGMIEGGdfIKEATWNTVSDIIQQGGTIIGSARSSEFRTREG 127
Cdd:TIGR02482 2 IGILTSGGDAPGMNAAIRAVVRTAIYHGFEVYGIRRGYKGLINGK--IEPLESKNVSGIIHRGGTILGTARCPEFKTEEV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 128 RLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTdlvqelvknqrvtaaaakkipyIQIVGLVGSIDNDFCGTDMTIG 207
Cdd:TIGR02482 80 REKAVENLKKLGIEGLVVIGGDGSYTGAQKLYEEGG----------------------IPVIGLPGTIDNDIPGTDYTIG 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 208 TDSALQRIISSIDAVVATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPenwRDVLCDKLSQMRSEGQRL 287
Cdd:TIGR02482 138 FDTALNTIIDAVDKIRDTATSHERAFVIEVMGRHAGDLALYAGIATGAEIIIIPEFDYD---IDELIQRLKEQHEAGKKH 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 288 NIIIVAEGAIDRDGKAITAEdvktaVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEmtEESEPCvIS 367
Cdd:TIGR02482 215 SIIIVAEGNIVGSAKEVAKK-----IEEKTGIETRVTVLGHTQRGGSPSAFDRVLASRLGAKAVELLLE--GKGGVM-IG 286
|
330
....*....|...
gi 25147584 368 IDGNVMVRVPLLK 380
Cdd:TIGR02482 287 IQNNKIVTHPIEE 299
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
48-395 |
1.71e-93 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 295.47 E-value: 1.71e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 48 LAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLIYEGYEGMIEGGdfIKEATWNTVSDIIQQGGTIIGSARSSEFRTREG 127
Cdd:cd00763 3 IGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRDGYAGLIAGD--IVPLDRYSVSDIINRGGTFLGSARFPEFKDEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 128 RLKAATNLINRGIGRLVCIGGDGSLTGAntfrlewtdlvqelvknQRVTAAAakkipyIQIVGLVGSIDNDFCGTDMTIG 207
Cdd:cd00763 81 QAKAIEQLKKHGIDALVVIGGDGSYMGA-----------------MRLTEHG------FPCVGLPGTIDNDIPGTDYTIG 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 208 TDSALQRIISSIDAVVATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEwpAPENWRDVLcDKLSQMRSEGQRL 287
Cdd:cd00763 138 FDTALNTVVEAIDRIRDTSSSHQRISVVEVMGRHCGDIALAAGIAGGAEFIVIPE--AEFDREEVA-NRIKAGIERGKKH 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 288 NIIIVAEGAIDrdgkaitAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEmtEESEPCViS 367
Cdd:cd00763 215 AIVVVAEGVYD-------VDELAKEIEEATGFETRATVLGHIQRGGSPTAFDRILASRMGAYAVELLLA--GKGGLAV-G 284
|
330 340
....*....|....*....|....*...
gi 25147584 368 IDGNVMVRVPLLKCVERTQMVQKAMADK 395
Cdd:cd00763 285 IQNEQLVHHDIIDAIENMKPFKKDWLAL 312
|
|
| PFK_mixed |
TIGR02483 |
phosphofructokinase; Members of this family that are characterized, save one, are ... |
48-378 |
1.53e-68 |
|
phosphofructokinase; Members of this family that are characterized, save one, are phosphofructokinases dependent on pyrophosphate (EC 2.7.1.90) rather than ATP (EC 2.7.1.11). The exception is one of three phosphofructokinases from Streptomyces coelicolor. Family members are both bacterial and archaeal. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 274155 [Multi-domain] Cd Length: 324 Bit Score: 229.50 E-value: 1.53e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 48 LAIYTSGGDSQGMNSAVRSITRMAIYC-GCKVYLIYEGYEGMIEGgDFIKEATWNTVSDIIQQGGTIIGSARSSEFRT-R 125
Cdd:TIGR02483 2 IGVLTGGGDCPGLNAVIRGVVRRAIAEyGWEVIGIRDGWRGLLEG-DTVPLLDLEDVRGILPRGGTILGSSRTNPFKYeE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 126 EGRLKAATNLINRGIGRLVCIGGDGSLTGAntfrlewtdlvQELVKNqrvtaaaakkipYIQIVGLVGSIDNDFCGTDMT 205
Cdd:TIGR02483 81 DGDDKIVANLKELGLDALIAIGGDGTLGIA-----------RRLADK------------GLPVVGVPKTIDNDLEATDYT 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 206 IGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPApeNWRDVlCDKLSQMRSEGQ 285
Cdd:TIGR02483 138 FGFDTAVEIATEALDRLHTTAESHHRVMVVEVMGRHAGWIALHSGIAGGADVILIPEIPF--DIDSV-CEKVRERFARGK 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 286 RLNIIIVAEGAIDRDGKAITAEDVKTA----------------VKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAE 349
Cdd:TIGR02483 215 RFAIVVVAEGAKPKGGEMVVQEGVKDAfghvrlggignwlaeeIERRTGIETRATVLGHLQRGGSPSAFDRVLATRFGVA 294
|
330 340
....*....|....*....|....*....
gi 25147584 350 AVFALMEMTEESepcVISIDGNVMVRVPL 378
Cdd:TIGR02483 295 AVDLVHEGQFGH---MVALRGTDIVYVPI 320
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
436-723 |
3.86e-62 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 212.54 E-value: 3.86e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 436 NVAVINVGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQ--KSLPTEKTM 513
Cdd:cd00363 2 KIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIYEGYAGLVEGDIKELDWESVSDIINRGGTIIGSArcKEFRTEEGR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 514 PQLAAQLKKHNIQALLLVGGFEAYHSTIILAEN-REKYPEFciPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIK 592
Cdd:cd00363 82 AKAAENLKKHGIDALVVIGGDGSYTGADLLTEEwPSKYQGF--NVIGLPGTIDNDIKGTDYTIGFDTALKTIVEAIDRIR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 593 QSATgTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLVVRNEWA----DK 668
Cdd:cd00363 160 DTAS-SHQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAADEWEEEMVDVIKKRRERGKRHGIVIVAEGAidfiPK 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 25147584 669 NLTTDFVQNLFDSEGKknFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALEFLL 723
Cdd:cd00363 239 PITEKLLAKLVEERLG--FDTRATVLGHVQRGGTPTAFDRILASRLGAEAVELLL 291
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
436-784 |
8.14e-57 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 198.38 E-value: 8.14e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 436 NVAVINVGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLP--TEKTM 513
Cdd:COG0205 3 RIGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEGDIIDLTREDVSGILQRGGTILGSSRSKPfkTEEGR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 514 PQLAAQLKKHNIQALLLVGGFEAYHSTIILAENREkypefcIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQ 593
Cdd:COG0205 83 EKALENLKKLGIDALVVIGGDGSLDGAAKLAEEYG------IPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDRLRD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 594 SATGTkRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLsddVDVILSKMEVGAKRYLVV-----RNEWADK 668
Cdd:COG0205 157 TAASH-ERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDLDKL---LEKLKERRKRGKGYSIIVvaegaGDEDGEA 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 669 NLTTD---FVQNLFDSEGKK---------NFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALEFLLiqlkenltadnkv 736
Cdd:COG0205 233 VLEADtdaFGHVRLGGIGEYlakeieertGIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLL------------- 299
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 25147584 737 iakSAHTATLLGLKGRKVVFTPVQDLKKEtdfEHRLPSEQ-WWMALRPL 784
Cdd:COG0205 300 ---EGKTGVMVGIRRGEIVLVPLEEVANK---EKPVDPDSpLIQLAREL 342
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
437-723 |
2.80e-56 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 196.09 E-value: 2.80e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 437 VAVINVGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKS--LPTEKTMP 514
Cdd:cd00763 3 IGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRDGYAGLIAGDIVPLDRYSVSDIINRGGTFLGSARFpeFKDEEGQA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 515 QLAAQLKKHNIQALLLVGGFEAYHSTIILAEnrEKYPefcipmCV-IPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQ 593
Cdd:cd00763 83 KAIEQLKKHGIDALVVIGGDGSYMGAMRLTE--HGFP------CVgLPGTIDNDIPGTDYTIGFDTALNTVVEAIDRIRD 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 594 SATgTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLsddVDVILSKMEVGAKRYLVVRNEwadknLTTD 673
Cdd:cd00763 155 TSS-SHQRISVVEVMGRHCGDIALAAGIAGGAEFIVIPEAEFDREEV---ANRIKAGIERGKKHAIVVVAE-----GVYD 225
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 25147584 674 FVQNLFDSEGKKNFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALEFLL 723
Cdd:cd00763 226 VDELAKEIEEATGFETRATVLGHIQRGGSPTAFDRILASRMGAYAVELLL 275
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
444-772 |
2.84e-55 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 193.37 E-value: 2.84e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 444 APagGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLP--TEKTMPQLAAQLK 521
Cdd:PRK03202 13 AP--GMNAAIRAVVRTAISEGLEVYGIYDGYAGLLEGDIVKLDLKSVSDIINRGGTILGSARFPEfkDEEGRAKAIENLK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 522 KHNIQALLLVGGFEAYHSTIILAENRekypefcIPmCV-IPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATgTKR 600
Cdd:PRK03202 91 KLGIDALVVIGGDGSYMGAKRLTEHG-------IP-VIgLPGTIDNDIAGTDYTIGFDTALNTAVEAIDRLRDTAS-SHE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 601 RVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLsddVDVILSKMEVGAKRYLVVRNEWA-DKNLTTDFVQNLF 679
Cdd:PRK03202 162 RVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFDIEEL---CAKIKKGRERGKKHAIIVVAEGVmPAEELAKEIEERT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 680 DSEgkknftTRVNVLGHVQQGGSPTPFDRNMGTKLAARALEFLLiqlkenltaDNKviaksahTATLLGLKGRKVVFTPV 759
Cdd:PRK03202 239 GLE------TRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLL---------EGK-------GGRMVGIQNNKIVHVPI 296
|
330
....*....|....*
gi 25147584 760 QDL--KKETDFEHRL 772
Cdd:PRK03202 297 EEAveNMKHPFDKDL 311
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
44-351 |
3.82e-51 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 191.78 E-value: 3.82e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 44 KGRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLIYEGYEGMIEGGdfIKEATWNTVSDIIQQGGTIIGSARSsefr 123
Cdd:TIGR02478 388 SRLRIAIIHVGAPAGGMNAATRSAVRYALARGHTVIAIHNGFSGLARHD--VRELTWSDVEGWVGEGGSELGTNRS---- 461
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 124 TREGRLKA-ATNLINRGIGRLVCIGGDGSLTGANTfrlewtdLVQELVKnqrvtaAAAKKIPyiqIVGLVGSIDNDFCGT 202
Cdd:TIGR02478 462 LPGDDLGTiAYYFQQHKIDGLIIIGGFEAFEALYQ-------LDAAREK------YPAFRIP---MVVIPATISNNVPGT 525
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 203 DMTIGTDSALQRIISSIDAVVATAQ-SHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEwpAPENWRDV--LCDKLSQ 279
Cdd:TIGR02478 526 EYSLGSDTALNEITEYCDNIKQSASaSKRRVFVVETMGGYSGYLATMAGLATGADAAYIPE--EGISLKDLqeDIEHLKE 603
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 25147584 280 MRSEGQRLNIIIVAEGAIdrdgKAITAEDVKTAVKE--KLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAV 351
Cdd:TIGR02478 604 TFAEGRAGKLILRNEKAS----KVYTTDFIARIISEegKGRFDARTAVLGHMQQGGSPSPFDRVRATRLAIRAV 673
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
44-351 |
5.05e-45 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 166.01 E-value: 5.05e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 44 KGRTLAIYTSGGDSQGMNSAVRSITRMAI--YcGCKVYLIYEGYEGMIEGGDFIKEATWNTVSDIIQQGGTIIGSA---- 117
Cdd:PRK14071 3 EKKRIGILTSGGDCAGLNAVIRAVVHRARgtY-GWEVIGIRDATQGLMARPPQYIELDLDQVDDLLRMGGTILGTTnkgd 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 118 -------------RSSEFRTREGRLkaatnlinrGIGRLVCIGGDGSLTgantfrlewtdLVQELvknqrvtaAAAKKIP 184
Cdd:PRK14071 82 pfafpmpdgslrdRSQEIIDGYHSL---------GLDALIGIGGDGSLA-----------ILRRL--------AQQGGIN 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 185 yiqIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWP 264
Cdd:PRK14071 134 ---LVGIPKTIDNDVGATEVSIGFDTAVNIATEALDRLHFTAASHNRVMILEVMGRDAGHIALAAGIAGGADVILIPEIP 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 265 apenWR-DVLCDKLSQMRSEGQRLNIIIVAEGAIDRDGKAITAED-------------VKTAVKEKLKYDTRVTILGHVQ 330
Cdd:PRK14071 211 ----YTlENVCKKIRERQEEGKNFCLVVVSEAVRTEEGEQVTKTQalgedryggigqyLAEQIAERTGAETRVTVLGHIQ 286
|
330 340
....*....|....*....|.
gi 25147584 331 RGGAPSAFDRLLGCRMGAEAV 351
Cdd:PRK14071 287 RGGIPSPRDRLLASAFGVAAV 307
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
47-413 |
1.56e-35 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 140.95 E-value: 1.56e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 47 TLAIYTSGGDSQGMNSAVRSITRMAI--YCGCKVYLIYEGYEGMIEGgDFIKeATWNTVSDIIQQGGTIIGSARSSEFRT 124
Cdd:PTZ00286 89 KAGIVTCGGLCPGLNVVIRELVMNLInnYGVKTIYGAKYGYKGLYKE-DWIK-LDPKDVKTIHRLGGTILGSSRGGFDPK 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 125 regrlKAATNLINRGIGRLVCIGGDGSLTGANTfrlewtdLVQELVKnqrvtaaaaKKIPyIQIVGLVGSIDNDFCGTDM 204
Cdd:PTZ00286 167 -----VMVDTLIRHGINILFTLGGDGTHRGALA-------IYKELRR---------RKLN-ISVVGIPKTIDNDIPIIDE 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 205 TIGTDSALQRIISSIDAVVATAQSHQRAF-VIEVMGRHCGYLALVAALAS-EADFCFIPEWPAPEnwrDVLCDKLSQmRS 282
Cdd:PTZ00286 225 SFGFQTAVEEAQNAIRAAYVEAKSAKNGVgIVKLMGRDSGFIALHASVASaDVNVCLIPEFDIPL---EGVLEYIEQ-RL 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 283 EGQRLNIIIVAEGAID--RDGKAITAED-------------VKTAVKEKLKYDTRVTILGHVQ-----RGGAPSAFDRLL 342
Cdd:PTZ00286 301 QKKGHCVIVVAEGAGQslKDADLDLGTDasgnkklwdigvyLKDEITKYLKKKKPEHTVKYIDpsymiRAVPANAADAKF 380
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25147584 343 GCRMGAEAVFALME-MTEesepCVISIDGNVMVRVPLlkcvertqmvqKAMADKdWTTAVMLRGRSFQRNLE 413
Cdd:PTZ00286 381 CTQLAQNAVHGAMAgFTG----FIIGHVHNNYVMIPI-----------KEMSGN-YRRRVNPEGRLWQRMLA 436
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
49-296 |
7.87e-25 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 108.42 E-value: 7.87e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 49 AIYTSGGDSQGMNSAVRSITRMAIYC-GCK-VYLIYEGYEGMIE--GGDFIkEATWNTVSDIIQQGGTIIGSARssefrt 124
Cdd:PRK06830 84 AIVTCGGLCPGLNDVIRAIVLELHHHyGVRrILGIRYGYQGLIPryGHDPV-ELTPEVVADIHEFGGTILGSSR------ 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 125 reGRLKAAT---NLINRGIGRLVCIGGDGSLTGANTfrlewtdLVQElvknqrvtaAAAKKIPyIQIVGLVGSIDNDFCG 201
Cdd:PRK06830 157 --GPQDPEEivdTLERMNINILFVIGGDGTLRGASA-------IAEE---------IERRGLK-ISVIGIPKTIDNDINF 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 202 TDMTIGTDSALQRIISSIDAVVATAQShqrAF----VIEVMGRHCGYLALVAALAS-EADFCFIPEWPAPENWRDVLCDK 276
Cdd:PRK06830 218 IQKSFGFETAVEKATEAIRCAHVEANG---APngigLVKLMGRHSGFIAAYAALASkDVNFVLIPEVPFDLEGPNGLLAA 294
|
250 260
....*....|....*....|
gi 25147584 277 LSQmRSEGQRLNIIIVAEGA 296
Cdd:PRK06830 295 LEK-RLAERGHAVIVVAEGA 313
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
437-720 |
5.44e-23 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 101.69 E-value: 5.44e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 437 VAVINVGAPAGGMNAAVRSYVRMALYHQ-CTVYGIEDSFEGLANG--SFKQFKWSDVTNWAMNGGSFLGT-QKSLPTEKT 512
Cdd:PRK14071 7 IGILTSGGDCAGLNAVIRAVVHRARGTYgWEVIGIRDATQGLMARppQYIELDLDQVDDLLRMGGTILGTtNKGDPFAFP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 513 MP---------QLAAQLKKHNIQALLLVGGfeaYHSTIILaenREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINE 583
Cdd:PRK14071 87 MPdgslrdrsqEIIDGYHSLGLDALIGIGG---DGSLAIL---RRLAQQGGINLVGIPKTIDNDVGATEVSIGFDTAVNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 584 ICQMIDKIKQSAtGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDvdvILSKMEVGAKRYLVVRN 663
Cdd:PRK14071 161 ATEALDRLHFTA-ASHNRVMILEVMGRDAGHIALAAGIAGGADVILIPEIPYTLENVCKK---IRERQEEGKNFCLVVVS 236
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 25147584 664 EwADKNLTTDFVQNLFdSEGKKNF-----------------TTRVNVLGHVQQGGSPTPFDRNMGTKLAARALE 720
Cdd:PRK14071 237 E-AVRTEEGEQVTKTQ-ALGEDRYggigqylaeqiaertgaETRVTVLGHIQRGGIPSPRDRLLASAFGVAAVD 308
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
49-320 |
6.95e-20 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 93.66 E-value: 6.95e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 49 AIYTSGGDSQGMNSAVRSITrmaiyCGC-------KVYLIYEGYEGmieggdFIKEATWN----TVSDIIQQGGTIIGSA 117
Cdd:PLN02564 91 CIVTCGGLCPGLNTVIREIV-----CGLsymygvtRILGIDGGYRG------FYSRNTIPltpkVVNDIHKRGGTILGTS 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 118 RSSEFRTregrlKAATNLINRGIGRLVCIGGDGSLTGANtfrlewtdLVQELVKNQRVTAAAAkkipyiqivGLVGSIDN 197
Cdd:PLN02564 160 RGGHDTS-----KIVDSIQDRGINQVYIIGGDGTQKGAS--------VIYEEIRRRGLKVAVA---------GIPKTIDN 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 198 DFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAF-VIEVMGRHCGYLALVAALAS-EADFCFIPEWPAPENWRDVLCD 275
Cdd:PLN02564 218 DIPVIDKSFGFDTAVEEAQRAINAAHVEAESVENGIgLVKLMGRYSGFIAMYATLASrDVDCCLIPESPFYLEGKGGLFE 297
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 25147584 276 KLSQMRSEGQRLnIIIVAEGA-IDRDGKAITAEDVKTAVKEKLKYD 320
Cdd:PLN02564 298 FIEKRLKENGHM-VIVVAEGAgQDLIAESMESSDLQDASGNKLLLD 342
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
437-661 |
9.45e-17 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 83.94 E-value: 9.45e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 437 VAVINVGAPAGGMNAAVRSYVRMAL--YHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMp 514
Cdd:PTZ00286 90 AGIVTCGGLCPGLNVVIRELVMNLInnYGVKTIYGAKYGYKGLYKEDWIKLDPKDVKTIHRLGGTILGSSRGGFDPKVM- 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 515 qlAAQLKKHNIQALLLVGGFEAYHSTIILAE--NREKYPefcIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIK 592
Cdd:PTZ00286 169 --VDTLIRHGINILFTLGGDGTHRGALAIYKelRRRKLN---ISVVGIPKTIDNDIPIIDESFGFQTAVEEAQNAIRAAY 243
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 593 QSATGTKRRVFIVETMGGYCGYLATLSALSSG-ADNAYIFEEPFTVQDLsddVDVILSKMEvgAKRYLVV 661
Cdd:PTZ00286 244 VEAKSAKNGVGIVKLMGRDSGFIALHASVASAdVNVCLIPEFDIPLEGV---LEYIEQRLQ--KKGHCVI 308
|
|
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
177-354 |
2.33e-15 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 79.13 E-value: 2.33e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 177 AAAAKKIPY-IQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSI-----DAVVATAQShqRAFVIEVMGRHCGYLALVAA 250
Cdd:PRK14072 123 SQLAKKMGYpIRCIGIPKTIDNDLPGTDHCPGFGSAAKYIATSVleaalDVAAMANTS--KVFILEVMGRHAGWLAAAAA 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 251 LASE-----ADFCFIPEWPAPEnwrdvlcDK-LSQMRSEGQRLN--IIIVAEGAIDRDGKAI----TAED---------- 308
Cdd:PRK14072 201 LAKQnpddaPHLIYLPERPFDE-------EKfLADVRAIVKRYGycVVVVSEGIRDADGKFIaeagLAEDafghaqlggv 273
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 25147584 309 ---VKTAVKEKLKYDTRVTILGHVQR--GGAPSAFDRLLGCRMGAEAV-FAL 354
Cdd:PRK14072 274 apvLANLIKEKLGKKVHWAVLDYLQRaaRHIASKTDVEEAYAVGKAAVeYAL 325
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
49-264 |
2.90e-15 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 78.70 E-value: 2.90e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 49 AIYTSGGDSQGMNSAVRSIT-RMAIYCGCKVYLIYEGYEGMIEGGDFIKEATWNTVSDIIQQGGTIIGSARSSEfRTREg 127
Cdd:PLN02884 57 AIVTCGGLCPGLNDVIRQIVfTLEIYGVKNIVGIPFGYRGFFEKGLSEMPLSRKVVQNIHLSGGSLLGVSRGGA-KTSD- 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 128 rlkAATNLINRGIGRLVCIGGDGSLTGANTFRLEwtdlvqelvknqrvtaaAAKKIPYIQIVGLVGSIDNDFCGTDMTIG 207
Cdd:PLN02884 135 ---IVDSIEARGINMLFVLGGNGTHAGANAIHNE-----------------CRKRKMKVSVVGVPKTIDNDILLMDKTFG 194
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 25147584 208 TDSALQRIISSIDAVVATAQSHQRAF-VIEVMGRHCGYLALVAALAS-EADFCFIPEWP 264
Cdd:PLN02884 195 FDTAVEEAQRAINSAYIEAHSAYHGIgLVKLMGRSSGFIAMHASLASgQVDICLIPEVP 253
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
436-637 |
1.65e-08 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 57.51 E-value: 1.65e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 436 NVAVINVGAPAGGMNAAVRSYV-RMALYHQCTVYGIEDSFEGLANGSFKQFKWSD--VTNWAMNGGSFLGTQKSLPTekt 512
Cdd:PLN02884 55 KAAIVTCGGLCPGLNDVIRQIVfTLEIYGVKNIVGIPFGYRGFFEKGLSEMPLSRkvVQNIHLSGGSLLGVSRGGAK--- 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 513 MPQLAAQLKKHNIQALLLVGGfEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIK 592
Cdd:PLN02884 132 TSDIVDSIEARGINMLFVLGG-NGTHAGANAIHNECRKRKMKVSVVGVPKTIDNDILLMDKTFGFDTAVEEAQRAINSAY 210
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 25147584 593 QSATGTKRRVFIVETMGGYCGYLATLSALSSG-ADNAYIFEEPFTV 637
Cdd:PLN02884 211 IEAHSAYHGIGLVKLMGRSSGFIAMHASLASGqVDICLIPEVPFTL 256
|
|
| PRK06555 |
PRK06555 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated |
46-303 |
9.19e-08 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated
Pssm-ID: 180620 [Multi-domain] Cd Length: 403 Bit Score: 55.01 E-value: 9.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 46 RTLAIYTSGGDSQGMNSAVRSI----TRMAIycgcKVYLIY--EGYEGMIeGGDFIK--EATWNTVSDIIQQGGTIIGSA 117
Cdd:PRK06555 4 KKVALLTAGGLAPCLSSAVGGLieryTEIAP----EVEIIAyrSGYQGLL-LGDSIEitPAVRANAGLLHRYGGSPIGNS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 118 RSSEFRT---------REGR--LK-AATNLINRGIGRLVCIGGDGSLTGAntfrlewTDLVQELVKNQrvtaaaakkipY 185
Cdd:PRK06555 79 RVKLTNVadcvkrglvKEGEnpLKvAAERLAADGVDILHTIGGDDTNTTA-------ADLAAYLAENG-----------Y 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 186 -IQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAFVI-EVMGRHCGYLALVAALASEadfcfipEW 263
Cdd:PRK06555 141 dLTVVGLPKTIDNDVVPIRQSLGAWTAAEQGARFFDNVINEHSANPRMLIIhEVMGRNCGWLTAATARAYR-------EW 213
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 25147584 264 PAPENWRDVLcdklsQMRSEGQRLNIIIVAEGAIDRDGKA 303
Cdd:PRK06555 214 LDRQEYVPGF-----GLSAERWDIHAVYLPEMAFDLEAEA 248
|
|
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
520-701 |
2.10e-06 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 51.01 E-value: 2.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 520 LKKHNIQALLLVGGFEAYHSTIILAENREK--YPEFCIPmcvIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQ--SA 595
Cdd:PRK14072 99 FKAHDIGYFFYNGGNDSMDTALKVSQLAKKmgYPIRCIG---IPKTIDNDLPGTDHCPGFGSAAKYIATSVLEAALdvAA 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 596 TGTKRRVFIVETMGGYCGYLATLSALSS-----GADNAYIFEEPFTVQDLSDDVDVILSKmevgAKRYLVVRNE---WAD 667
Cdd:PRK14072 176 MANTSKVFILEVMGRHAGWLAAAAALAKqnpddAPHLIYLPERPFDEEKFLADVRAIVKR----YGYCVVVVSEgirDAD 251
|
170 180 190
....*....|....*....|....*....|....
gi 25147584 668 KNLTTDFVqnlfdsegkknftTRVNVLGHVQQGG 701
Cdd:PRK14072 252 GKFIAEAG-------------LAEDAFGHAQLGG 272
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
43-298 |
3.46e-06 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 50.81 E-value: 3.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 43 FKGRT---LAIYTSGGDSQGMNSAVRsitrmAIYCGCKVYLIYEGYEGMIEGGDFIKEATWNTVSDIIQQ------GGTI 113
Cdd:PTZ00287 172 FKGGNvlkIGIILSGGPAPGGHNVIS-----GIYDYAKRYNEQSQVIGFLGGIDGLYSKNYVTITDSLMNrfrnlgGFNM 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 114 IGSARSsEFRTREGrLKAATNLINR-GIGRLVCIGGDGSLTGANtfrlewtdLVQELVknqrvtaaAAKKIPyIQIVGLV 192
Cdd:PTZ00287 247 LWSGRG-KVRNKDD-LIAIENIVAKlKLNGLVIIGGDGSNSNAA--------LISEYF--------AERQIP-ISIIGIP 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 193 GSIDNDFC--GTDMTIGTDSALQ---RIISSIDAVVATAqsHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPE 267
Cdd:PTZ00287 308 KTIDGDLKseAIEISFGFDTATKtysEVIGNLCTDVKTG--HNVYHVVRVMGRSASHVVLECALQTRPNIVLIGEEVEKE 385
|
250 260 270
....*....|....*....|....*....|....*.
gi 25147584 268 N--WRDV---LCDKLSQMRSEGQRLNIIIVAEGAID 298
Cdd:PTZ00287 386 NlsLKDIvsnIVNTILKRRSLNKNYGVILIPEGLIE 421
|
|
| Pyrophosphate_PFK |
cd00765 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
426-654 |
3.50e-06 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include pyrophosphate-dependent phosphofructokinases. These are found in bacteria as well as plants. These may be dimeric nonallosteric enzymes as in bacteria or allosteric heterotetramers as in plants.
Pssm-ID: 238390 Cd Length: 550 Bit Score: 50.64 E-value: 3.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 426 KDNLSEGHKFNVAVINVGAPA-GGMNAAVRSYVRMALYHQ-CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGG-SFLG 502
Cdd:cd00765 64 QDAPSSAPKLKIGIVLSGGQApGGHNVISGLFDYLKERAKgSTLYGFKGGPAGILKCDYIELNAEYIQPYRNTGGfDMIC 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 503 TQKS-LPTEKTMPQLAAQLKKHNIQALLLVGGFEAYHSTIILAENREKYPEfCIPMCVIPCTISNNVPGTMV--SLGSDT 579
Cdd:cd00765 144 SGRTkIETEDQFKQAEETAKKLDLDALVVIGGDDSNTNAALLAENFRSKGL-KTRVIGVPKTIDGDLKNKEIetSFGFDT 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 580 AINEICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEE----PFTVQDLSDD-VDVILSKMEVG 654
Cdd:cd00765 223 ATKIYSELIGNVMRDARSTGKYWHFVKLMGRSASHIALECALKTHPNICIISEEvsaqKQTLKNITDYmVDVICKRAELG 302
|
|
| Pyrophosphate_PFK |
cd00765 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
44-298 |
3.69e-06 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include pyrophosphate-dependent phosphofructokinases. These are found in bacteria as well as plants. These may be dimeric nonallosteric enzymes as in bacteria or allosteric heterotetramers as in plants.
Pssm-ID: 238390 Cd Length: 550 Bit Score: 50.25 E-value: 3.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 44 KGRTLAIYTSGGDSQGMNSAVR----SITRMAiyCGCKVYLIYEGYEGMIEGgDFIkEATWNTVSDIIQQGG-TIIGSAR 118
Cdd:cd00765 71 PKLKIGIVLSGGQAPGGHNVISglfdYLKERA--KGSTLYGFKGGPAGILKC-DYI-ELNAEYIQPYRNTGGfDMICSGR 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 119 SsEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANtfrlewtdLVQELVKNQRVTaaaakkipyIQIVGLVGSIDND 198
Cdd:cd00765 147 T-KIETEDQFKQAEETAKKLDLDALVVIGGDDSNTNAA--------LLAENFRSKGLK---------TRVIGVPKTIDGD 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 199 FCGTDMTI--GTDSALQRIISSIDAVVATAQSHQRAF-VIEVMGRHCGYLALVAALASEADFCFIPEWPAPE-----NWR 270
Cdd:cd00765 209 LKNKEIETsfGFDTATKIYSELIGNVMRDARSTGKYWhFVKLMGRSASHIALECALKTHPNICIISEEVSAQkqtlkNIT 288
|
250 260
....*....|....*....|....*...
gi 25147584 271 DVLCDKLSQMRSEGQRLNIIIVAEGAID 298
Cdd:cd00765 289 DYMVDVICKRAELGYNFGVVLVPEGLIE 316
|
|
| PRK07085 |
PRK07085 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
84-297 |
6.59e-05 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 235930 Cd Length: 555 Bit Score: 46.45 E-value: 6.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 84 GYEGMIEGGdfIKEATWNTVSDIIQQGG-TIIGSARSsEFRTREGRLKAATNLINRGIGRLVCIGGDGSltgantfrlew 162
Cdd:PRK07085 111 GPLGLLNGK--YIEITEEVIDEYRNTGGfDMIGSGRT-KIETEEQKEACLETVKKLKLDGLVIIGGDDS----------- 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 163 tdlvqelvkNqrvTAAA------AKKIPYIQIVGLVGSIDNDFCGT--DMTIGTDSALqRIISSI------DAVVATAQS 228
Cdd:PRK07085 177 ---------N---TNAAilaeyfAKHGCKTQVIGVPKTIDGDLKNEfiETSFGFDTAT-KTYSEMignisrDALSAKKYW 243
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 25147584 229 HqrafVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWR-----DVLCDKLSQMRSEGQRLNIIIVAEGAI 297
Cdd:PRK07085 244 H----FIKLMGRSASHIALECALQTHPNICLISEEVAEKKMSlqdivHYIASVIADRAAKGKNYGVILIPEGLI 313
|
|
| PTZ00468 |
PTZ00468 |
phosphofructokinase family protein; Provisional |
439-633 |
7.04e-05 |
|
phosphofructokinase family protein; Provisional
Pssm-ID: 185647 [Multi-domain] Cd Length: 1328 Bit Score: 46.51 E-value: 7.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 439 VINVGAPAGGMN--AAVRSYVRMAlYHQCTVYGIEDSFEGLANGSFKQFKWSDVtNWAMNGGSF---LGTQKSLPTEKTM 513
Cdd:PTZ00468 108 VLSGGQASGGHNviAGLMSYIKLC-NQSSQLFGFLGGPEGVYSERYRELTEDDI-NGILNQGGFniiCSGRHKIETEEQM 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 514 PQLAAQLKKHNIQALLLVGGFEAYHSTIILAENREKYPEFCIpmcVIPC--TISNNVPGTMV--SLGSDTAINEICQMID 589
Cdd:PTZ00468 186 RASLEICEKLKLHGLVVIGGDDSNTNAAVLAEYFKRNSSSTV---VVGCpkTIDGDLKNEVIetSFGYDTAVKTYSEQIG 262
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 25147584 590 KIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEE 633
Cdd:PTZ00468 263 SIMDAIKTEGYGYYFVRLMGRSASHITLECGLQTRANMILIGEE 306
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
560-635 |
7.68e-05 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 45.89 E-value: 7.68e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 25147584 560 IPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSS-GADNAYIFEEPF 635
Cdd:PLN02564 211 IPKTIDNDIPVIDKSFGFDTAVEEAQRAINAAHVEAESVENGIGLVKLMGRYSGFIAMYATLASrDVDCCLIPESPF 287
|
|
| PRK07085 |
PRK07085 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
423-661 |
4.25e-04 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 235930 Cd Length: 555 Bit Score: 43.76 E-value: 4.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 423 TVEKDNLSEGHKFNVAVINVGAPA-GGMNaavrsyVRMALYH-------QCTVYGIEDSFEGLANGSFKQFKwSDVTNWA 494
Cdd:PRK07085 59 TFVKGSESSSKPLKVGVILSGGQApGGHN------VIAGLFDglkklnpDSKLFGFIGGPLGLLNGKYIEIT-EEVIDEY 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 495 MNGGSF--LGTQKS-LPTEKTMPQLAAQLKKHNIQALLLVGGFEAYHSTIILAEnreKYPEFCIPMCVI--PCTISNNVP 569
Cdd:PRK07085 132 RNTGGFdmIGSGRTkIETEEQKEACLETVKKLKLDGLVIIGGDDSNTNAAILAE---YFAKHGCKTQVIgvPKTIDGDLK 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25147584 570 GTMV--SLGSDTAINEICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEE----PFTVQDLSDD 643
Cdd:PRK07085 209 NEFIetSFGFDTATKTYSEMIGNISRDALSAKKYWHFIKLMGRSASHIALECALQTHPNICLISEEvaekKMSLQDIVHY 288
|
250
....*....|....*....
gi 25147584 644 -VDVILSKMEVGaKRYLVV 661
Cdd:PRK07085 289 iASVIADRAAKG-KNYGVI 306
|
|
| |
