Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain; This family consists of several ...
119-318
1.23e-110
Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain; This family consists of several inositol 1, 3, 4-trisphosphate 5/6-kinase proteins. Inositol 1,3,4-trisphosphate is at a branch point in inositol phosphate metabolism. It is dephosphorylated by specific phosphatases to either inositol 3,4-bisphosphate or inositol 1,3-bisphosphate. Alternatively, it is phosphorylated to inositol 1,3,4,6-tetrakisphosphate or inositol 1,3,4,5-tetrakisphosphate by inositol trisphosphate 5/6-kinase. This entry represents the ATP-grasp domain.
:
Pssm-ID: 368606 Cd Length: 201 Bit Score: 323.26 E-value: 1.23e-110
Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain; This family consists of several ...
9-100
8.24e-42
Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain; This family consists of several inositol 1, 3, 4-trisphosphate 5/6-kinase proteins. Inositol 1,3,4-trisphosphate is at a branch point in inositol phosphate metabolism. It is dephosphorylated by specific phosphatases to either inositol 3,4-bisphosphate or inositol 1,3-bisphosphate. Alternatively, it is phosphorylated to inositol 1,3,4,6-tetrakisphosphate or inositol 1,3,4,5-tetrakisphosphate by inositol trisphosphate 5/6-kinase. This entry represents the N-terminal pre-ATP-grasp domain.
The actual alignment was detected with superfamily member pfam17927:
Pssm-ID: 407776 Cd Length: 80 Bit Score: 142.23 E-value: 8.24e-42
Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain; This family consists of several ...
119-318
1.23e-110
Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain; This family consists of several inositol 1, 3, 4-trisphosphate 5/6-kinase proteins. Inositol 1,3,4-trisphosphate is at a branch point in inositol phosphate metabolism. It is dephosphorylated by specific phosphatases to either inositol 3,4-bisphosphate or inositol 1,3-bisphosphate. Alternatively, it is phosphorylated to inositol 1,3,4,6-tetrakisphosphate or inositol 1,3,4,5-tetrakisphosphate by inositol trisphosphate 5/6-kinase. This entry represents the ATP-grasp domain.
Pssm-ID: 368606 Cd Length: 201 Bit Score: 323.26 E-value: 1.23e-110
Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain; This family consists of several ...
9-100
8.24e-42
Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain; This family consists of several inositol 1, 3, 4-trisphosphate 5/6-kinase proteins. Inositol 1,3,4-trisphosphate is at a branch point in inositol phosphate metabolism. It is dephosphorylated by specific phosphatases to either inositol 3,4-bisphosphate or inositol 1,3-bisphosphate. Alternatively, it is phosphorylated to inositol 1,3,4,6-tetrakisphosphate or inositol 1,3,4,5-tetrakisphosphate by inositol trisphosphate 5/6-kinase. This entry represents the N-terminal pre-ATP-grasp domain.
Pssm-ID: 407776 Cd Length: 80 Bit Score: 142.23 E-value: 8.24e-42
Glutathione synthase, LysX or RimK-type ligase, ATP-grasp superfamily [Amino acid transport ...
24-305
1.25e-10
Glutathione synthase, LysX or RimK-type ligase, ATP-grasp superfamily [Amino acid transport and metabolism, Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis, Secondary metabolites biosynthesis, transport and catabolism]; Glutathione synthase, LysX or RimK-type ligase, ATP-grasp superfamily is part of the Pathway/BioSystem: Lysine biosynthesis
Pssm-ID: 439959 [Multi-domain] Cd Length: 289 Bit Score: 61.88 E-value: 1.25e-10
Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain; This family consists of several ...
119-318
1.23e-110
Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain; This family consists of several inositol 1, 3, 4-trisphosphate 5/6-kinase proteins. Inositol 1,3,4-trisphosphate is at a branch point in inositol phosphate metabolism. It is dephosphorylated by specific phosphatases to either inositol 3,4-bisphosphate or inositol 1,3-bisphosphate. Alternatively, it is phosphorylated to inositol 1,3,4,6-tetrakisphosphate or inositol 1,3,4,5-tetrakisphosphate by inositol trisphosphate 5/6-kinase. This entry represents the ATP-grasp domain.
Pssm-ID: 368606 Cd Length: 201 Bit Score: 323.26 E-value: 1.23e-110
Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain; This family consists of several ...
9-100
8.24e-42
Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain; This family consists of several inositol 1, 3, 4-trisphosphate 5/6-kinase proteins. Inositol 1,3,4-trisphosphate is at a branch point in inositol phosphate metabolism. It is dephosphorylated by specific phosphatases to either inositol 3,4-bisphosphate or inositol 1,3-bisphosphate. Alternatively, it is phosphorylated to inositol 1,3,4,6-tetrakisphosphate or inositol 1,3,4,5-tetrakisphosphate by inositol trisphosphate 5/6-kinase. This entry represents the N-terminal pre-ATP-grasp domain.
Pssm-ID: 407776 Cd Length: 80 Bit Score: 142.23 E-value: 8.24e-42
Glutathione synthase, LysX or RimK-type ligase, ATP-grasp superfamily [Amino acid transport ...
24-305
1.25e-10
Glutathione synthase, LysX or RimK-type ligase, ATP-grasp superfamily [Amino acid transport and metabolism, Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis, Secondary metabolites biosynthesis, transport and catabolism]; Glutathione synthase, LysX or RimK-type ligase, ATP-grasp superfamily is part of the Pathway/BioSystem: Lysine biosynthesis
Pssm-ID: 439959 [Multi-domain] Cd Length: 289 Bit Score: 61.88 E-value: 1.25e-10
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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