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Conserved domains on  [gi|71051607|ref|NP_766450|]
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FRAS1-related extracellular matrix protein 2 precursor [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Frem_N pfam19309
Frem protein N-terminal domain; This entry represents a presumed domain found at the ...
65-277 3.25e-123

Frem protein N-terminal domain; This entry represents a presumed domain found at the N-terminus of Frem related proteins.


:

Pssm-ID: 466034  Cd Length: 202  Bit Score: 386.69  E-value: 3.25e-123
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607     65 IVVANRGLRVPFGREVWLDPLRDLVLQVQPGDRCTVTVLDNDALAQRPGHLSPKRFACDYGPGEVRYSHLGARSPSRDRV 144
Cdd:pfam19309    1 ILIANRGLRVPFGRSVWLDPLRDLVIQVQPGDRCEVTVLDNDPLPQRPGALSPRRFPCDFGPREVQYTHFGSRSPSRDRV 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    145 RLQLRYDAPGGAIVLPLALEVEVVFTQLEIVTRNLPLVVEELLGTSNALDDRSLEFAYQPETEECRVGILSGLSALPRYG 224
Cdd:pfam19309   81 RLQLRYDAPTDTLVLPFTLEVEVVFSQLEIVTRNLPLTVEKLLGTSNPIDRRVLEFAYDPGTERCKVTVLPGAGGLPRYG 160
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 71051607    225 ELLHYPQVqggagdrgtskTLLMDCKAFQELGVRYRHTAPSRSPNRDWLPMVV 277
Cdd:pfam19309  161 RLVNATGA-----------PLMVDCEAFLRAGVRYQHTATTSSPNRDYVPMVV 202
Cadherin_3 pfam16184
Cadherin-like;
1505-1612 5.67e-34

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 127.72  E-value: 5.67e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1505 NPVFRTFRISISDVDNKKPVVTIHN-LVVSESESKLITPFELTVEDRDTPDRLLKFIVTQVPVHGHLLFNNTRSVMV--F 1581
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVtnF 80
                           90       100       110
                   ....*....|....*....|....*....|.
gi 71051607   1582 TKQDLNENLISYKHDGTESTEDSFSFTVTDG 1612
Cdd:pfam16184   81 TQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1275-1390 1.05e-33

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 126.95  E-value: 1.05e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1275 HSVEKMVLIVVIPVDDETPRMTINNGLEIEIGETKVINNKVLMATDLDSDDKSLVYIIRYGPGHGLLQRQKPLGafENIT 1354
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPG--LPVT 78
                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 71051607   1355 lgmNFTQDEVDRNLIQYVHFGQEGIRDLIKFDVTDG 1390
Cdd:pfam16184   79 ---NFTQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1395-1503 8.42e-33

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 124.25  E-value: 8.42e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1395 IDRYFYVTIGSVDIVFPDVV-SKGVSLKEGGKVTLTTDLLSTSDLNSPDENLVFTITRAPMRGHLECTDRRGLSITSFTQ 1473
Cdd:pfam16184    3 VPFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQ 82
                           90       100       110
                   ....*....|....*....|....*....|
gi 71051607   1474 LQLAGNKIYYIHTAeDEVKMDSFEFQVTDG 1503
Cdd:pfam16184   83 ADIDSGLVVYVHDG-SESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
415-532 3.87e-32

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 122.33  E-value: 3.87e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    415 SDPFAFMVVVKPMNTLAPVVTRNTGLILYEGQYRPLTgpigsgPQNLVISDEDDL-EAVRLEVVAGLRHGHLVILGSPSs 493
Cdd:pfam16184    2 SVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPIT------PDLLQAEDPDTPpEDLTYTVVQGPSHGHLALKGAPG- 74
                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 71051607    494 dSAPKTFTVAELAAGQVVYQHDDKDgSLSDNLVLRMSDG 532
Cdd:pfam16184   75 -LPVTNFTQADIDSGLVVYVHDGSE-STSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1163-1273 1.03e-26

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 106.92  E-value: 1.03e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1163 SERQIFPIVIIPTNDEQPEMFMRE-FMVMEGMSLVVNRLILNAADADIPRDDLTFTITRFPTHGHVMNQLiNGTVLVESF 1241
Cdd:pfam16184    2 SVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKG-APGLPVTNF 80
                           90       100       110
                   ....*....|....*....|....*....|..
gi 71051607   1242 TLDQiIESSSIIYEHDDSETQEDSFVIKLTDG 1273
Cdd:pfam16184   81 TQAD-IDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
536-665 7.41e-26

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 104.22  E-value: 7.41e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    536 HQVQFLFPITLVPVDDQPPVLNANTGLTVAEGETVPIPPLTLSATDIDSDDSQLVFVLLPPFSSlGHLLLRqrhvpqeeq 615
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSH-GHLALK--------- 70
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 71051607    616 glwqkqgSFYERTVTEWRQQDITEGKLFYRHSGphsPGPVMDQFMFRVQD 665
Cdd:pfam16184   71 -------GAPGLPVTNFTQADIDSGLVVYVHDG---SESTSDGFTFQVTD 110
Cadherin_3 pfam16184
Cadherin-like;
1042-1159 2.64e-23

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 96.90  E-value: 2.64e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1042 VTVWVTILPVDSQAPEISLGEQFVVLEGDKSVISLTHLSAEDMDSLKDDLLCTIVIQPTSGYVENispapgseKSRAGVA 1121
Cdd:pfam16184    5 FTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLAL--------KGAPGLP 76
                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 71051607   1122 ISAFTLKDLRQGHINYvqsVHRGVEPVEDRFIFRCSDG 1159
Cdd:pfam16184   77 VTNFTQADIDSGLVVY---VHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1630-1742 2.23e-21

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 91.51  E-value: 2.23e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1630 PQVMKIQVLPVDNSVPQIVVNKGastLRTLATGHlgFMITSKILKVEDRDSLHFSLRFIVTEAPQHGYLLNLGQGNHSVT 1709
Cdd:pfam16184    4 PFTFNITIIPVNDEAPVLTTNTG---LRLWEGSS--RPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVT 78
                           90       100       110
                   ....*....|....*....|....*....|...
gi 71051607   1710 QFTQADIDDMKICYVlRERANATSDMFHFIVED 1742
Cdd:pfam16184   79 NFTQADIDSGLVVYV-HDGSESTSDGFTFQVTD 110
caca super family cl36745
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ...
2097-2332 5.78e-18

sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]


The actual alignment was detected with superfamily member TIGR00845:

Pssm-ID: 273296 [Multi-domain]  Cd Length: 928  Bit Score: 91.78  E-value: 5.78e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   2097 AALGEPSKATVSINDSASDLP-KMQFKERVYTCNENDGRV-VAMIYRSGDIQHRSSVRCYTRQGSAQVMMDFEERPntdv 2174
Cdd:TIGR00845  379 AARKAVSMHEVATDDEENDPVsKIFFEPGHYTCLENCGTVaLTVVRRGGDLTNTVYVDYRTEDGTANAGSDYEFTE---- 454
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   2175 STVTFLPGEMEKPCVLELMDDAVYEDVEELRLVLGTPQGSSAFGAAVGEQNETL----------IKIQDEADKAVIKFGE 2244
Cdd:TIGR00845  455 GTLVFKPGETQKEFRIGIIDDDIFEEDEHFYVRLSNLRVGSEDGILEANHVSAVaqlaspntatVTILDDDHAGIFTFEE 534
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   2245 TKFSVTEPSRpgesvVVKIPVIRQGDTSKVSIVRVHTKDGSAT-SGEDYHPVSEEIEFKEGETQHTVEIEVIFDGVREMR 2323
Cdd:TIGR00845  535 DVFHVSESIG-----IMEVKVLRTSGARGTVIVPYRTVEGTARgGGKDFEDTCGELEFENDETEKTIRVKIVDDEEYEKN 609

                   ....*....
gi 71051607   2324 EAFTVHLKP 2332
Cdd:TIGR00845  610 DTFFIELGE 618
caca super family cl36745
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ...
1760-1997 1.64e-17

sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]


The actual alignment was detected with superfamily member TIGR00845:

Pssm-ID: 273296 [Multi-domain]  Cd Length: 928  Bit Score: 90.24  E-value: 1.64e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1760 ISFEKEYYLINEDSKFLDIVLTRRGY-LGETSFISIGTRDGTAEKDRDFKGkAQKQVQFNPGQTRASWRVRILSDGEHEH 1838
Cdd:TIGR00845  402 IFFEPGHYTCLENCGTVALTVVRRGGdLTNTVYVDYRTEDGTANAGSDYEF-TEGTLVFKPGETQKEFRIGIIDDDIFEE 480
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1839 SETFQVVLSEP---------------VLAILEFPTVTTVEIIDpGDESTVF-IPQSEYSVEEDVGELFIPIRRSGDISRE 1902
Cdd:TIGR00845  481 DEHFYVRLSNLrvgsedgileanhvsAVAQLASPNTATVTILD-DDHAGIFtFEEDVFHVSESIGIMEVKVLRTSGARGT 559
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1903 LMVICYTQQGTATStvrtsvlSYSDYisrpEDHSSVIRFDKDEREKMCRILVIDDSLYEEEETFQVLLSMPMGGRIGDKF 1982
Cdd:TIGR00845  560 VIVPYRTVEGTARG-------GGKDF----EDTCGELEFENDETEKTIRVKIVDDEEYEKNDTFFIELGEPRWAKRGIKA 628
                          250
                   ....*....|....*
gi 71051607   1983 PGANVTILTDRDDEP 1997
Cdd:TIGR00845  629 ALLLNETITDDDQKL 643
Cadherin_3 super family cl28802
Cadherin-like;
804-909 3.70e-17

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 79.57  E-value: 3.70e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    804 PGTFTLYLQPVDNQPPEIV-NTGFTVEEKGHHILRETELHVSDVDTDVTHISFTLTQAPKHGHMQISGRPLHVGGQFHLE 882
Cdd:pfam16184    4 PFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQA 83
                           90       100
                   ....*....|....*....|....*..
gi 71051607    883 DIKHGRISYWNSGDESLTDSCSLEVSD 909
Cdd:pfam16184   84 DIDSGLVVYVHDGSESTSDGFTFQVTD 110
Calx-beta super family cl02522
Calx-beta domain;
1999-2091 6.11e-16

Calx-beta domain;


The actual alignment was detected with superfamily member pfam03160:

Pssm-ID: 413355 [Multi-domain]  Cd Length: 91  Bit Score: 75.36  E-value: 6.11e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1999 FYFGDTQYSVDESAGYVELQVWRTGTDLSKPSSVTVRsrkTESLSADAGTDYVGISRNLDFAPGVNMQTVRVVILDDLgr 2078
Cdd:pfam03160    4 IGFEPPTYQVSENDGVAEVCVVRMSGTLRRTVVVPYR---TEDGTATAGDDYEPVEGELVFGPGETEKCINVTIIDDD-- 78
                           90
                   ....*....|...
gi 71051607   2079 pILEGIEKFELVL 2091
Cdd:pfam03160   79 -VYEGDENFFVLL 90
Cadherin_3 super family cl28802
Cadherin-like;
672-797 6.71e-14

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 70.32  E-value: 6.71e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    672 QSGIQRFVIRIHPVDRLPPELGSGCPLRmvVQESQLTPLRKRWLHYTDLDTDDRELQYTVTQPPtdtdeNHspaplGTLV 751
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLR--LWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGP-----SH-----GHLA 68
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 71051607    752 FTDNPSVVVSHFTQAQVNHHKIAYrppgQELGVAARVAQFQFQVED 797
Cdd:pfam16184   69 LKGAPGLPVTNFTQADIDSGLVVY----VHDGSESTSDGFTFQVTD 110
Cadherin_3 super family cl28802
Cadherin-like;
912-1026 1.04e-12

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 66.86  E-value: 1.04e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    912 HVVPITLRVNVRPGDREGPMSVLPAGtlesyLDVLENGATEVTANIIKGAYQGTDDLMLTFLLEGPPSYGEILVNGAP-- 989
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTG-----LRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPgl 75
                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 71051607    990 -AEQFTQRDILEGSVVYAHTSGEigllPKADSFNLSLS 1026
Cdd:pfam16184   76 pVTNFTQADIDSGLVVYVHDGSE----STSDGFTFQVT 109
Cadherin_3 super family cl28802
Cadherin-like;
329-389 1.16e-09

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 58.00  E-value: 1.16e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 71051607    329 TALTPDMLAAEDAESDPDLLIFNLTSafQPGQGYLVSTDDRSLPLSSFTQRDLRLLKIAYQ 389
Cdd:pfam16184   35 RPITPDLLQAEDPDTPPEDLTYTVVQ--GPSHGHLALKGAPGLPVTNFTQADIDSGLVVYV 93
 
Name Accession Description Interval E-value
Frem_N pfam19309
Frem protein N-terminal domain; This entry represents a presumed domain found at the ...
65-277 3.25e-123

Frem protein N-terminal domain; This entry represents a presumed domain found at the N-terminus of Frem related proteins.


Pssm-ID: 466034  Cd Length: 202  Bit Score: 386.69  E-value: 3.25e-123
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607     65 IVVANRGLRVPFGREVWLDPLRDLVLQVQPGDRCTVTVLDNDALAQRPGHLSPKRFACDYGPGEVRYSHLGARSPSRDRV 144
Cdd:pfam19309    1 ILIANRGLRVPFGRSVWLDPLRDLVIQVQPGDRCEVTVLDNDPLPQRPGALSPRRFPCDFGPREVQYTHFGSRSPSRDRV 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    145 RLQLRYDAPGGAIVLPLALEVEVVFTQLEIVTRNLPLVVEELLGTSNALDDRSLEFAYQPETEECRVGILSGLSALPRYG 224
Cdd:pfam19309   81 RLQLRYDAPTDTLVLPFTLEVEVVFSQLEIVTRNLPLTVEKLLGTSNPIDRRVLEFAYDPGTERCKVTVLPGAGGLPRYG 160
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 71051607    225 ELLHYPQVqggagdrgtskTLLMDCKAFQELGVRYRHTAPSRSPNRDWLPMVV 277
Cdd:pfam19309  161 RLVNATGA-----------PLMVDCEAFLRAGVRYQHTATTSSPNRDYVPMVV 202
Cadherin_3 pfam16184
Cadherin-like;
1505-1612 5.67e-34

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 127.72  E-value: 5.67e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1505 NPVFRTFRISISDVDNKKPVVTIHN-LVVSESESKLITPFELTVEDRDTPDRLLKFIVTQVPVHGHLLFNNTRSVMV--F 1581
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVtnF 80
                           90       100       110
                   ....*....|....*....|....*....|.
gi 71051607   1582 TKQDLNENLISYKHDGTESTEDSFSFTVTDG 1612
Cdd:pfam16184   81 TQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1275-1390 1.05e-33

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 126.95  E-value: 1.05e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1275 HSVEKMVLIVVIPVDDETPRMTINNGLEIEIGETKVINNKVLMATDLDSDDKSLVYIIRYGPGHGLLQRQKPLGafENIT 1354
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPG--LPVT 78
                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 71051607   1355 lgmNFTQDEVDRNLIQYVHFGQEGIRDLIKFDVTDG 1390
Cdd:pfam16184   79 ---NFTQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1395-1503 8.42e-33

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 124.25  E-value: 8.42e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1395 IDRYFYVTIGSVDIVFPDVV-SKGVSLKEGGKVTLTTDLLSTSDLNSPDENLVFTITRAPMRGHLECTDRRGLSITSFTQ 1473
Cdd:pfam16184    3 VPFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQ 82
                           90       100       110
                   ....*....|....*....|....*....|
gi 71051607   1474 LQLAGNKIYYIHTAeDEVKMDSFEFQVTDG 1503
Cdd:pfam16184   83 ADIDSGLVVYVHDG-SESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
415-532 3.87e-32

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 122.33  E-value: 3.87e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    415 SDPFAFMVVVKPMNTLAPVVTRNTGLILYEGQYRPLTgpigsgPQNLVISDEDDL-EAVRLEVVAGLRHGHLVILGSPSs 493
Cdd:pfam16184    2 SVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPIT------PDLLQAEDPDTPpEDLTYTVVQGPSHGHLALKGAPG- 74
                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 71051607    494 dSAPKTFTVAELAAGQVVYQHDDKDgSLSDNLVLRMSDG 532
Cdd:pfam16184   75 -LPVTNFTQADIDSGLVVYVHDGSE-STSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1163-1273 1.03e-26

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 106.92  E-value: 1.03e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1163 SERQIFPIVIIPTNDEQPEMFMRE-FMVMEGMSLVVNRLILNAADADIPRDDLTFTITRFPTHGHVMNQLiNGTVLVESF 1241
Cdd:pfam16184    2 SVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKG-APGLPVTNF 80
                           90       100       110
                   ....*....|....*....|....*....|..
gi 71051607   1242 TLDQiIESSSIIYEHDDSETQEDSFVIKLTDG 1273
Cdd:pfam16184   81 TQAD-IDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
536-665 7.41e-26

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 104.22  E-value: 7.41e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    536 HQVQFLFPITLVPVDDQPPVLNANTGLTVAEGETVPIPPLTLSATDIDSDDSQLVFVLLPPFSSlGHLLLRqrhvpqeeq 615
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSH-GHLALK--------- 70
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 71051607    616 glwqkqgSFYERTVTEWRQQDITEGKLFYRHSGphsPGPVMDQFMFRVQD 665
Cdd:pfam16184   71 -------GAPGLPVTNFTQADIDSGLVVYVHDG---SESTSDGFTFQVTD 110
Cadherin_3 pfam16184
Cadherin-like;
1042-1159 2.64e-23

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 96.90  E-value: 2.64e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1042 VTVWVTILPVDSQAPEISLGEQFVVLEGDKSVISLTHLSAEDMDSLKDDLLCTIVIQPTSGYVENispapgseKSRAGVA 1121
Cdd:pfam16184    5 FTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLAL--------KGAPGLP 76
                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 71051607   1122 ISAFTLKDLRQGHINYvqsVHRGVEPVEDRFIFRCSDG 1159
Cdd:pfam16184   77 VTNFTQADIDSGLVVY---VHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1630-1742 2.23e-21

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 91.51  E-value: 2.23e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1630 PQVMKIQVLPVDNSVPQIVVNKGastLRTLATGHlgFMITSKILKVEDRDSLHFSLRFIVTEAPQHGYLLNLGQGNHSVT 1709
Cdd:pfam16184    4 PFTFNITIIPVNDEAPVLTTNTG---LRLWEGSS--RPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVT 78
                           90       100       110
                   ....*....|....*....|....*....|...
gi 71051607   1710 QFTQADIDDMKICYVlRERANATSDMFHFIVED 1742
Cdd:pfam16184   79 NFTQADIDSGLVVYV-HDGSESTSDGFTFQVTD 110
caca TIGR00845
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ...
2097-2332 5.78e-18

sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]


Pssm-ID: 273296 [Multi-domain]  Cd Length: 928  Bit Score: 91.78  E-value: 5.78e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   2097 AALGEPSKATVSINDSASDLP-KMQFKERVYTCNENDGRV-VAMIYRSGDIQHRSSVRCYTRQGSAQVMMDFEERPntdv 2174
Cdd:TIGR00845  379 AARKAVSMHEVATDDEENDPVsKIFFEPGHYTCLENCGTVaLTVVRRGGDLTNTVYVDYRTEDGTANAGSDYEFTE---- 454
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   2175 STVTFLPGEMEKPCVLELMDDAVYEDVEELRLVLGTPQGSSAFGAAVGEQNETL----------IKIQDEADKAVIKFGE 2244
Cdd:TIGR00845  455 GTLVFKPGETQKEFRIGIIDDDIFEEDEHFYVRLSNLRVGSEDGILEANHVSAVaqlaspntatVTILDDDHAGIFTFEE 534
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   2245 TKFSVTEPSRpgesvVVKIPVIRQGDTSKVSIVRVHTKDGSAT-SGEDYHPVSEEIEFKEGETQHTVEIEVIFDGVREMR 2323
Cdd:TIGR00845  535 DVFHVSESIG-----IMEVKVLRTSGARGTVIVPYRTVEGTARgGGKDFEDTCGELEFENDETEKTIRVKIVDDEEYEKN 609

                   ....*....
gi 71051607   2324 EAFTVHLKP 2332
Cdd:TIGR00845  610 DTFFIELGE 618
caca TIGR00845
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ...
1760-1997 1.64e-17

sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]


Pssm-ID: 273296 [Multi-domain]  Cd Length: 928  Bit Score: 90.24  E-value: 1.64e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1760 ISFEKEYYLINEDSKFLDIVLTRRGY-LGETSFISIGTRDGTAEKDRDFKGkAQKQVQFNPGQTRASWRVRILSDGEHEH 1838
Cdd:TIGR00845  402 IFFEPGHYTCLENCGTVALTVVRRGGdLTNTVYVDYRTEDGTANAGSDYEF-TEGTLVFKPGETQKEFRIGIIDDDIFEE 480
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1839 SETFQVVLSEP---------------VLAILEFPTVTTVEIIDpGDESTVF-IPQSEYSVEEDVGELFIPIRRSGDISRE 1902
Cdd:TIGR00845  481 DEHFYVRLSNLrvgsedgileanhvsAVAQLASPNTATVTILD-DDHAGIFtFEEDVFHVSESIGIMEVKVLRTSGARGT 559
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1903 LMVICYTQQGTATStvrtsvlSYSDYisrpEDHSSVIRFDKDEREKMCRILVIDDSLYEEEETFQVLLSMPMGGRIGDKF 1982
Cdd:TIGR00845  560 VIVPYRTVEGTARG-------GGKDF----EDTCGELEFENDETEKTIRVKIVDDEEYEKNDTFFIELGEPRWAKRGIKA 628
                          250
                   ....*....|....*
gi 71051607   1983 PGANVTILTDRDDEP 1997
Cdd:TIGR00845  629 ALLLNETITDDDQKL 643
Cadherin_3 pfam16184
Cadherin-like;
804-909 3.70e-17

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 79.57  E-value: 3.70e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    804 PGTFTLYLQPVDNQPPEIV-NTGFTVEEKGHHILRETELHVSDVDTDVTHISFTLTQAPKHGHMQISGRPLHVGGQFHLE 882
Cdd:pfam16184    4 PFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQA 83
                           90       100
                   ....*....|....*....|....*..
gi 71051607    883 DIKHGRISYWNSGDESLTDSCSLEVSD 909
Cdd:pfam16184   84 DIDSGLVVYVHDGSESTSDGFTFQVTD 110
Calx-beta pfam03160
Calx-beta domain;
1999-2091 6.11e-16

Calx-beta domain;


Pssm-ID: 397326 [Multi-domain]  Cd Length: 91  Bit Score: 75.36  E-value: 6.11e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1999 FYFGDTQYSVDESAGYVELQVWRTGTDLSKPSSVTVRsrkTESLSADAGTDYVGISRNLDFAPGVNMQTVRVVILDDLgr 2078
Cdd:pfam03160    4 IGFEPPTYQVSENDGVAEVCVVRMSGTLRRTVVVPYR---TEDGTATAGDDYEPVEGELVFGPGETEKCINVTIIDDD-- 78
                           90
                   ....*....|...
gi 71051607   2079 pILEGIEKFELVL 2091
Cdd:pfam03160   79 -VYEGDENFFVLL 90
Calx-beta pfam03160
Calx-beta domain;
2239-2330 2.43e-14

Calx-beta domain;


Pssm-ID: 397326 [Multi-domain]  Cd Length: 91  Bit Score: 70.74  E-value: 2.43e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   2239 VIKFGETKFSVTEpsrpgESVVVKIPVIRQ-GDTSKVSIVRVHTKDGSATSGEDYHPVSEEIEFKEGETQHTVEIEVIFD 2317
Cdd:pfam03160    3 VIGFEPPTYQVSE-----NDGVAEVCVVRMsGTLRRTVVVPYRTEDGTATAGDDYEPVEGELVFGPGETEKCINVTIIDD 77
                           90
                   ....*....|...
gi 71051607   2318 GVREMREAFTVHL 2330
Cdd:pfam03160   78 DVYEGDENFFVLL 90
Cadherin_3 pfam16184
Cadherin-like;
672-797 6.71e-14

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 70.32  E-value: 6.71e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    672 QSGIQRFVIRIHPVDRLPPELGSGCPLRmvVQESQLTPLRKRWLHYTDLDTDDRELQYTVTQPPtdtdeNHspaplGTLV 751
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLR--LWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGP-----SH-----GHLA 68
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 71051607    752 FTDNPSVVVSHFTQAQVNHHKIAYrppgQELGVAARVAQFQFQVED 797
Cdd:pfam16184   69 LKGAPGLPVTNFTQADIDSGLVVY----VHDGSESTSDGFTFQVTD 110
Calx_beta smart00237
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin ...
2239-2330 1.15e-13

Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins)


Pssm-ID: 197594 [Multi-domain]  Cd Length: 90  Bit Score: 68.82  E-value: 1.15e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    2239 VIKFGETKFSVTEpsrpgESVVVKIPVIRQGDTSKVSIVRVHTKDGSATSGEDYHPVSEEIEFKEGETQHTVEIEVIFDG 2318
Cdd:smart00237    3 SVGFEQPVYTVSE-----SDGEVEVCVVRTGGARGPVVVPYSTEDGTATAGSDYEPVPGELTFPPGETEKEIRIKIIDDD 77
                            90
                    ....*....|..
gi 71051607    2319 VREMREAFTVHL 2330
Cdd:smart00237   78 IYEKDETFYVRL 89
Calx_beta smart00237
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin ...
1999-2091 4.37e-13

Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins)


Pssm-ID: 197594 [Multi-domain]  Cd Length: 90  Bit Score: 67.28  E-value: 4.37e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    1999 FYFGDTQYSVDESAGYVELQVWRTGtDLSKPSSVTVRsrkTESLSADAGTDYVGISRNLDFAPGVNMQTVRVVILDDlgr 2078
Cdd:smart00237    4 VGFEQPVYTVSESDGEVEVCVVRTG-GARGPVVVPYS---TEDGTATAGSDYEPVPGELTFPPGETEKEIRIKIIDD--- 76
                            90
                    ....*....|...
gi 71051607    2079 PILEGIEKFELVL 2091
Cdd:smart00237   77 DIYEKDETFYVRL 89
Calx_beta smart00237
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin ...
1871-1971 7.92e-13

Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins)


Pssm-ID: 197594 [Multi-domain]  Cd Length: 90  Bit Score: 66.51  E-value: 7.92e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    1871 STVFIPQSEYSVEEDVGELFIPIRRSGDISRELMVICYTQQGTATSTvrtsvlsySDYISRPedhsSVIRFDKDEREKMC 1950
Cdd:smart00237    2 GSVGFEQPVYTVSESDGEVEVCVVRTGGARGPVVVPYSTEDGTATAG--------SDYEPVP----GELTFPPGETEKEI 69
                            90       100
                    ....*....|....*....|.
gi 71051607    1951 RILVIDDSLYEEEETFQVLLS 1971
Cdd:smart00237   70 RIKIIDDDIYEKDETFYVRLS 90
Cadherin_3 pfam16184
Cadherin-like;
912-1026 1.04e-12

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 66.86  E-value: 1.04e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    912 HVVPITLRVNVRPGDREGPMSVLPAGtlesyLDVLENGATEVTANIIKGAYQGTDDLMLTFLLEGPPSYGEILVNGAP-- 989
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTG-----LRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPgl 75
                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 71051607    990 -AEQFTQRDILEGSVVYAHTSGEigllPKADSFNLSLS 1026
Cdd:pfam16184   76 pVTNFTQADIDSGLVVYVHDGSE----STSDGFTFQVT 109
Calx-beta pfam03160
Calx-beta domain;
1871-1971 2.46e-12

Calx-beta domain;


Pssm-ID: 397326 [Multi-domain]  Cd Length: 91  Bit Score: 64.96  E-value: 2.46e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1871 STVFIPQSEYSVEEDVGELFIPI-RRSGDISRELMVICYTQQGTATSTvrtsvlsySDYISRPEDhssvIRFDKDEREKM 1949
Cdd:pfam03160    2 GVIGFEPPTYQVSENDGVAEVCVvRMSGTLRRTVVVPYRTEDGTATAG--------DDYEPVEGE----LVFGPGETEKC 69
                           90       100
                   ....*....|....*....|..
gi 71051607   1950 CRILVIDDSLYEEEETFQVLLS 1971
Cdd:pfam03160   70 INVTIIDDDVYEGDENFFVLLS 91
Cadherin_3 pfam16184
Cadherin-like;
329-389 1.16e-09

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 58.00  E-value: 1.16e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 71051607    329 TALTPDMLAAEDAESDPDLLIFNLTSafQPGQGYLVSTDDRSLPLSSFTQRDLRLLKIAYQ 389
Cdd:pfam16184   35 RPITPDLLQAEDPDTPPEDLTYTVVQ--GPSHGHLALKGAPGLPVTNFTQADIDSGLVVYV 93
 
Name Accession Description Interval E-value
Frem_N pfam19309
Frem protein N-terminal domain; This entry represents a presumed domain found at the ...
65-277 3.25e-123

Frem protein N-terminal domain; This entry represents a presumed domain found at the N-terminus of Frem related proteins.


Pssm-ID: 466034  Cd Length: 202  Bit Score: 386.69  E-value: 3.25e-123
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607     65 IVVANRGLRVPFGREVWLDPLRDLVLQVQPGDRCTVTVLDNDALAQRPGHLSPKRFACDYGPGEVRYSHLGARSPSRDRV 144
Cdd:pfam19309    1 ILIANRGLRVPFGRSVWLDPLRDLVIQVQPGDRCEVTVLDNDPLPQRPGALSPRRFPCDFGPREVQYTHFGSRSPSRDRV 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    145 RLQLRYDAPGGAIVLPLALEVEVVFTQLEIVTRNLPLVVEELLGTSNALDDRSLEFAYQPETEECRVGILSGLSALPRYG 224
Cdd:pfam19309   81 RLQLRYDAPTDTLVLPFTLEVEVVFSQLEIVTRNLPLTVEKLLGTSNPIDRRVLEFAYDPGTERCKVTVLPGAGGLPRYG 160
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 71051607    225 ELLHYPQVqggagdrgtskTLLMDCKAFQELGVRYRHTAPSRSPNRDWLPMVV 277
Cdd:pfam19309  161 RLVNATGA-----------PLMVDCEAFLRAGVRYQHTATTSSPNRDYVPMVV 202
Cadherin_3 pfam16184
Cadherin-like;
1505-1612 5.67e-34

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 127.72  E-value: 5.67e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1505 NPVFRTFRISISDVDNKKPVVTIHN-LVVSESESKLITPFELTVEDRDTPDRLLKFIVTQVPVHGHLLFNNTRSVMV--F 1581
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVtnF 80
                           90       100       110
                   ....*....|....*....|....*....|.
gi 71051607   1582 TKQDLNENLISYKHDGTESTEDSFSFTVTDG 1612
Cdd:pfam16184   81 TQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1275-1390 1.05e-33

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 126.95  E-value: 1.05e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1275 HSVEKMVLIVVIPVDDETPRMTINNGLEIEIGETKVINNKVLMATDLDSDDKSLVYIIRYGPGHGLLQRQKPLGafENIT 1354
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPG--LPVT 78
                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 71051607   1355 lgmNFTQDEVDRNLIQYVHFGQEGIRDLIKFDVTDG 1390
Cdd:pfam16184   79 ---NFTQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1395-1503 8.42e-33

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 124.25  E-value: 8.42e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1395 IDRYFYVTIGSVDIVFPDVV-SKGVSLKEGGKVTLTTDLLSTSDLNSPDENLVFTITRAPMRGHLECTDRRGLSITSFTQ 1473
Cdd:pfam16184    3 VPFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQ 82
                           90       100       110
                   ....*....|....*....|....*....|
gi 71051607   1474 LQLAGNKIYYIHTAeDEVKMDSFEFQVTDG 1503
Cdd:pfam16184   83 ADIDSGLVVYVHDG-SESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
415-532 3.87e-32

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 122.33  E-value: 3.87e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    415 SDPFAFMVVVKPMNTLAPVVTRNTGLILYEGQYRPLTgpigsgPQNLVISDEDDL-EAVRLEVVAGLRHGHLVILGSPSs 493
Cdd:pfam16184    2 SVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPIT------PDLLQAEDPDTPpEDLTYTVVQGPSHGHLALKGAPG- 74
                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 71051607    494 dSAPKTFTVAELAAGQVVYQHDDKDgSLSDNLVLRMSDG 532
Cdd:pfam16184   75 -LPVTNFTQADIDSGLVVYVHDGSE-STSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1163-1273 1.03e-26

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 106.92  E-value: 1.03e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1163 SERQIFPIVIIPTNDEQPEMFMRE-FMVMEGMSLVVNRLILNAADADIPRDDLTFTITRFPTHGHVMNQLiNGTVLVESF 1241
Cdd:pfam16184    2 SVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKG-APGLPVTNF 80
                           90       100       110
                   ....*....|....*....|....*....|..
gi 71051607   1242 TLDQiIESSSIIYEHDDSETQEDSFVIKLTDG 1273
Cdd:pfam16184   81 TQAD-IDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
536-665 7.41e-26

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 104.22  E-value: 7.41e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    536 HQVQFLFPITLVPVDDQPPVLNANTGLTVAEGETVPIPPLTLSATDIDSDDSQLVFVLLPPFSSlGHLLLRqrhvpqeeq 615
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSH-GHLALK--------- 70
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 71051607    616 glwqkqgSFYERTVTEWRQQDITEGKLFYRHSGphsPGPVMDQFMFRVQD 665
Cdd:pfam16184   71 -------GAPGLPVTNFTQADIDSGLVVYVHDG---SESTSDGFTFQVTD 110
Cadherin_3 pfam16184
Cadherin-like;
1042-1159 2.64e-23

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 96.90  E-value: 2.64e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1042 VTVWVTILPVDSQAPEISLGEQFVVLEGDKSVISLTHLSAEDMDSLKDDLLCTIVIQPTSGYVENispapgseKSRAGVA 1121
Cdd:pfam16184    5 FTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLAL--------KGAPGLP 76
                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 71051607   1122 ISAFTLKDLRQGHINYvqsVHRGVEPVEDRFIFRCSDG 1159
Cdd:pfam16184   77 VTNFTQADIDSGLVVY---VHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1630-1742 2.23e-21

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 91.51  E-value: 2.23e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1630 PQVMKIQVLPVDNSVPQIVVNKGastLRTLATGHlgFMITSKILKVEDRDSLHFSLRFIVTEAPQHGYLLNLGQGNHSVT 1709
Cdd:pfam16184    4 PFTFNITIIPVNDEAPVLTTNTG---LRLWEGSS--RPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVT 78
                           90       100       110
                   ....*....|....*....|....*....|...
gi 71051607   1710 QFTQADIDDMKICYVlRERANATSDMFHFIVED 1742
Cdd:pfam16184   79 NFTQADIDSGLVVYV-HDGSESTSDGFTFQVTD 110
caca TIGR00845
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ...
2097-2332 5.78e-18

sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]


Pssm-ID: 273296 [Multi-domain]  Cd Length: 928  Bit Score: 91.78  E-value: 5.78e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   2097 AALGEPSKATVSINDSASDLP-KMQFKERVYTCNENDGRV-VAMIYRSGDIQHRSSVRCYTRQGSAQVMMDFEERPntdv 2174
Cdd:TIGR00845  379 AARKAVSMHEVATDDEENDPVsKIFFEPGHYTCLENCGTVaLTVVRRGGDLTNTVYVDYRTEDGTANAGSDYEFTE---- 454
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   2175 STVTFLPGEMEKPCVLELMDDAVYEDVEELRLVLGTPQGSSAFGAAVGEQNETL----------IKIQDEADKAVIKFGE 2244
Cdd:TIGR00845  455 GTLVFKPGETQKEFRIGIIDDDIFEEDEHFYVRLSNLRVGSEDGILEANHVSAVaqlaspntatVTILDDDHAGIFTFEE 534
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   2245 TKFSVTEPSRpgesvVVKIPVIRQGDTSKVSIVRVHTKDGSAT-SGEDYHPVSEEIEFKEGETQHTVEIEVIFDGVREMR 2323
Cdd:TIGR00845  535 DVFHVSESIG-----IMEVKVLRTSGARGTVIVPYRTVEGTARgGGKDFEDTCGELEFENDETEKTIRVKIVDDEEYEKN 609

                   ....*....
gi 71051607   2324 EAFTVHLKP 2332
Cdd:TIGR00845  610 DTFFIELGE 618
caca TIGR00845
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ...
1760-1997 1.64e-17

sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]


Pssm-ID: 273296 [Multi-domain]  Cd Length: 928  Bit Score: 90.24  E-value: 1.64e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1760 ISFEKEYYLINEDSKFLDIVLTRRGY-LGETSFISIGTRDGTAEKDRDFKGkAQKQVQFNPGQTRASWRVRILSDGEHEH 1838
Cdd:TIGR00845  402 IFFEPGHYTCLENCGTVALTVVRRGGdLTNTVYVDYRTEDGTANAGSDYEF-TEGTLVFKPGETQKEFRIGIIDDDIFEE 480
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1839 SETFQVVLSEP---------------VLAILEFPTVTTVEIIDpGDESTVF-IPQSEYSVEEDVGELFIPIRRSGDISRE 1902
Cdd:TIGR00845  481 DEHFYVRLSNLrvgsedgileanhvsAVAQLASPNTATVTILD-DDHAGIFtFEEDVFHVSESIGIMEVKVLRTSGARGT 559
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1903 LMVICYTQQGTATStvrtsvlSYSDYisrpEDHSSVIRFDKDEREKMCRILVIDDSLYEEEETFQVLLSMPMGGRIGDKF 1982
Cdd:TIGR00845  560 VIVPYRTVEGTARG-------GGKDF----EDTCGELEFENDETEKTIRVKIVDDEEYEKNDTFFIELGEPRWAKRGIKA 628
                          250
                   ....*....|....*
gi 71051607   1983 PGANVTILTDRDDEP 1997
Cdd:TIGR00845  629 ALLLNETITDDDQKL 643
Cadherin_3 pfam16184
Cadherin-like;
804-909 3.70e-17

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 79.57  E-value: 3.70e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    804 PGTFTLYLQPVDNQPPEIV-NTGFTVEEKGHHILRETELHVSDVDTDVTHISFTLTQAPKHGHMQISGRPLHVGGQFHLE 882
Cdd:pfam16184    4 PFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQA 83
                           90       100
                   ....*....|....*....|....*..
gi 71051607    883 DIKHGRISYWNSGDESLTDSCSLEVSD 909
Cdd:pfam16184   84 DIDSGLVVYVHDGSESTSDGFTFQVTD 110
caca TIGR00845
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ...
1866-2119 1.28e-16

sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]


Pssm-ID: 273296 [Multi-domain]  Cd Length: 928  Bit Score: 87.15  E-value: 1.28e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1866 DPGDE-STVFIPQSEYSVEEDVGELFIPI-RRSGDISRELMVICYTQQGTATSTvrtsvlsySDYISRpedhSSVIRFDK 1943
Cdd:TIGR00845  394 EENDPvSKIFFEPGHYTCLENCGTVALTVvRRGGDLTNTVYVDYRTEDGTANAG--------SDYEFT----EGTLVFKP 461
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1944 DEREKMCRILVIDDSLYEEEETFQVLLSMPmggRIGDK---FPG--------------ANVTILTDrDDEPAFYFGDTQY 2006
Cdd:TIGR00845  462 GETQKEFRIGIIDDDIFEEDEHFYVRLSNL---RVGSEdgiLEAnhvsavaqlaspntATVTILDD-DHAGIFTFEEDVF 537
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   2007 SVDESAGYVELQVWRTGtdlSKPSSVTVRSRKTESLSADAGTDYVGISRNLDFAPGVNMQTVRVVILDD----------- 2075
Cdd:TIGR00845  538 HVSESIGIMEVKVLRTS---GARGTVIVPYRTVEGTARGGGKDFEDTCGELEFENDETEKTIRVKIVDDeeyekndtffi 614
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 71051607   2076 -LGRPILegIEKFELVLRMPmNAALGEPSKATVSINDSASDLPKM 2119
Cdd:TIGR00845  615 eLGEPRW--AKRGIKAALLL-NETITDDDQKLTSKEEEERRIAEM 656
Calx-beta pfam03160
Calx-beta domain;
1999-2091 6.11e-16

Calx-beta domain;


Pssm-ID: 397326 [Multi-domain]  Cd Length: 91  Bit Score: 75.36  E-value: 6.11e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1999 FYFGDTQYSVDESAGYVELQVWRTGTDLSKPSSVTVRsrkTESLSADAGTDYVGISRNLDFAPGVNMQTVRVVILDDLgr 2078
Cdd:pfam03160    4 IGFEPPTYQVSENDGVAEVCVVRMSGTLRRTVVVPYR---TEDGTATAGDDYEPVEGELVFGPGETEKCINVTIIDDD-- 78
                           90
                   ....*....|...
gi 71051607   2079 pILEGIEKFELVL 2091
Cdd:pfam03160   79 -VYEGDENFFVLL 90
Calx-beta pfam03160
Calx-beta domain;
2239-2330 2.43e-14

Calx-beta domain;


Pssm-ID: 397326 [Multi-domain]  Cd Length: 91  Bit Score: 70.74  E-value: 2.43e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   2239 VIKFGETKFSVTEpsrpgESVVVKIPVIRQ-GDTSKVSIVRVHTKDGSATSGEDYHPVSEEIEFKEGETQHTVEIEVIFD 2317
Cdd:pfam03160    3 VIGFEPPTYQVSE-----NDGVAEVCVVRMsGTLRRTVVVPYRTEDGTATAGDDYEPVEGELVFGPGETEKCINVTIIDD 77
                           90
                   ....*....|...
gi 71051607   2318 GVREMREAFTVHL 2330
Cdd:pfam03160   78 DVYEGDENFFVLL 90
Cadherin_3 pfam16184
Cadherin-like;
672-797 6.71e-14

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 70.32  E-value: 6.71e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    672 QSGIQRFVIRIHPVDRLPPELGSGCPLRmvVQESQLTPLRKRWLHYTDLDTDDRELQYTVTQPPtdtdeNHspaplGTLV 751
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLR--LWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGP-----SH-----GHLA 68
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 71051607    752 FTDNPSVVVSHFTQAQVNHHKIAYrppgQELGVAARVAQFQFQVED 797
Cdd:pfam16184   69 LKGAPGLPVTNFTQADIDSGLVVY----VHDGSESTSDGFTFQVTD 110
caca TIGR00845
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ...
1992-2212 1.13e-13

sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]


Pssm-ID: 273296 [Multi-domain]  Cd Length: 928  Bit Score: 77.52  E-value: 1.13e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1992 DRDDEPAFYFGDTQYSVDESAGYVELQVWRTGTDLSKPSSVTVRsrkTESLSADAGTDYVGISRNLDFAPGVNMQTVRVV 2071
Cdd:TIGR00845  395 ENDPVSKIFFEPGHYTCLENCGTVALTVVRRGGDLTNTVYVDYR---TEDGTANAGSDYEFTEGTLVFKPGETQKEFRIG 471
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   2072 ILDDlgrPILEGIEKFELVLRMP---------------MNAALGEPSKATVSINDsaSDLPKM-QFKERVYTCNENDGRV 2135
Cdd:TIGR00845  472 IIDD---DIFEEDEHFYVRLSNLrvgsedgileanhvsAVAQLASPNTATVTILD--DDHAGIfTFEEDVFHVSESIGIM 546
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   2136 -VAMIYRSGdiqHRSSVRC--YTRQGSAQV-MMDFEERpntdVSTVTFLPGEMEKPCVLELMDDAVYEDVEELRLVLGTP 2211
Cdd:TIGR00845  547 eVKVLRTSG---ARGTVIVpyRTVEGTARGgGKDFEDT----CGELEFENDETEKTIRVKIVDDEEYEKNDTFFIELGEP 619

                   .
gi 71051607   2212 Q 2212
Cdd:TIGR00845  620 R 620
Calx_beta smart00237
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin ...
2239-2330 1.15e-13

Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins)


Pssm-ID: 197594 [Multi-domain]  Cd Length: 90  Bit Score: 68.82  E-value: 1.15e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    2239 VIKFGETKFSVTEpsrpgESVVVKIPVIRQGDTSKVSIVRVHTKDGSATSGEDYHPVSEEIEFKEGETQHTVEIEVIFDG 2318
Cdd:smart00237    3 SVGFEQPVYTVSE-----SDGEVEVCVVRTGGARGPVVVPYSTEDGTATAGSDYEPVPGELTFPPGETEKEIRIKIIDDD 77
                            90
                    ....*....|..
gi 71051607    2319 VREMREAFTVHL 2330
Cdd:smart00237   78 IYEKDETFYVRL 89
Calx_beta smart00237
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin ...
1999-2091 4.37e-13

Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins)


Pssm-ID: 197594 [Multi-domain]  Cd Length: 90  Bit Score: 67.28  E-value: 4.37e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    1999 FYFGDTQYSVDESAGYVELQVWRTGtDLSKPSSVTVRsrkTESLSADAGTDYVGISRNLDFAPGVNMQTVRVVILDDlgr 2078
Cdd:smart00237    4 VGFEQPVYTVSESDGEVEVCVVRTG-GARGPVVVPYS---TEDGTATAGSDYEPVPGELTFPPGETEKEIRIKIIDD--- 76
                            90
                    ....*....|...
gi 71051607    2079 PILEGIEKFELVL 2091
Cdd:smart00237   77 DIYEKDETFYVRL 89
Calx_beta smart00237
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin ...
1871-1971 7.92e-13

Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins)


Pssm-ID: 197594 [Multi-domain]  Cd Length: 90  Bit Score: 66.51  E-value: 7.92e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    1871 STVFIPQSEYSVEEDVGELFIPIRRSGDISRELMVICYTQQGTATSTvrtsvlsySDYISRPedhsSVIRFDKDEREKMC 1950
Cdd:smart00237    2 GSVGFEQPVYTVSESDGEVEVCVVRTGGARGPVVVPYSTEDGTATAG--------SDYEPVP----GELTFPPGETEKEI 69
                            90       100
                    ....*....|....*....|.
gi 71051607    1951 RILVIDDSLYEEEETFQVLLS 1971
Cdd:smart00237   70 RIKIIDDDIYEKDETFYVRLS 90
Cadherin_3 pfam16184
Cadherin-like;
912-1026 1.04e-12

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 66.86  E-value: 1.04e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    912 HVVPITLRVNVRPGDREGPMSVLPAGtlesyLDVLENGATEVTANIIKGAYQGTDDLMLTFLLEGPPSYGEILVNGAP-- 989
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTG-----LRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPgl 75
                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 71051607    990 -AEQFTQRDILEGSVVYAHTSGEigllPKADSFNLSLS 1026
Cdd:pfam16184   76 pVTNFTQADIDSGLVVYVHDGSE----STSDGFTFQVT 109
Calx-beta pfam03160
Calx-beta domain;
1871-1971 2.46e-12

Calx-beta domain;


Pssm-ID: 397326 [Multi-domain]  Cd Length: 91  Bit Score: 64.96  E-value: 2.46e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1871 STVFIPQSEYSVEEDVGELFIPI-RRSGDISRELMVICYTQQGTATSTvrtsvlsySDYISRPEDhssvIRFDKDEREKM 1949
Cdd:pfam03160    2 GVIGFEPPTYQVSENDGVAEVCVvRMSGTLRRTVVVPYRTEDGTATAG--------DDYEPVEGE----LVFGPGETEKC 69
                           90       100
                   ....*....|....*....|..
gi 71051607   1950 CRILVIDDSLYEEEETFQVLLS 1971
Cdd:pfam03160   70 INVTIIDDDVYEGDENFFVLLS 91
Calx_beta smart00237
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin ...
1760-1847 5.13e-10

Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins)


Pssm-ID: 197594 [Multi-domain]  Cd Length: 90  Bit Score: 58.42  E-value: 5.13e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    1760 ISFEKEYYLINEDSKFLDIVLTRRGYLGETSFISIGTRDGTAEKDRDFKGKAQkQVQFNPGQTRASWRVRILSDGEHEHS 1839
Cdd:smart00237    4 VGFEQPVYTVSESDGEVEVCVVRTGGARGPVVVPYSTEDGTATAGSDYEPVPG-ELTFPPGETEKEIRIKIIDDDIYEKD 82

                    ....*...
gi 71051607    1840 ETFQVVLS 1847
Cdd:smart00237   83 ETFYVRLS 90
Cadherin_3 pfam16184
Cadherin-like;
329-389 1.16e-09

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 58.00  E-value: 1.16e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 71051607    329 TALTPDMLAAEDAESDPDLLIFNLTSafQPGQGYLVSTDDRSLPLSSFTQRDLRLLKIAYQ 389
Cdd:pfam16184   35 RPITPDLLQAEDPDTPPEDLTYTVVQ--GPSHGHLALKGAPGLPVTNFTQADIDSGLVVYV 93
Calx-beta pfam03160
Calx-beta domain;
1760-1847 1.26e-09

Calx-beta domain;


Pssm-ID: 397326 [Multi-domain]  Cd Length: 91  Bit Score: 57.26  E-value: 1.26e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   1760 ISFEKEYYLINEDSKFLDIVLTRR-GYLGETSFISIGTRDGTAEKDRDFKGKAQkQVQFNPGQTRASWRVRILSDGEHEH 1838
Cdd:pfam03160    4 IGFEPPTYQVSENDGVAEVCVVRMsGTLRRTVVVPYRTEDGTATAGDDYEPVEG-ELVFGPGETEKCINVTIIDDDVYEG 82

                   ....*....
gi 71051607   1839 SETFQVVLS 1847
Cdd:pfam03160   83 DENFFVLLS 91
Calx-beta pfam03160
Calx-beta domain;
2117-2209 1.77e-08

Calx-beta domain;


Pssm-ID: 397326 [Multi-domain]  Cd Length: 91  Bit Score: 54.18  E-value: 1.77e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607   2117 PKMQFKERVYTCNENDGRV-VAMIYRSGDIQHRSSVRCYTRQGSAQVMMDFEERPntdvSTVTFLPGEMEKPCVLELMDD 2195
Cdd:pfam03160    2 GVIGFEPPTYQVSENDGVAeVCVVRMSGTLRRTVVVPYRTEDGTATAGDDYEPVE----GELVFGPGETEKCINVTIIDD 77
                           90
                   ....*....|....
gi 71051607   2196 AVYEDVEELRLVLG 2209
Cdd:pfam03160   78 DVYEGDENFFVLLS 91
Calx_beta smart00237
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin ...
2118-2209 2.69e-08

Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins)


Pssm-ID: 197594 [Multi-domain]  Cd Length: 90  Bit Score: 53.41  E-value: 2.69e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71051607    2118 KMQFKERVYTCNENDGRVVAMIYRSGDIQHRSSVRCYTRQGSAQVMMDFEERPntdvSTVTFLPGEMEKPCVLELMDDAV 2197
Cdd:smart00237    3 SVGFEQPVYTVSESDGEVEVCVVRTGGARGPVVVPYSTEDGTATAGSDYEPVP----GELTFPPGETEKEIRIKIIDDDI 78
                            90
                    ....*....|..
gi 71051607    2198 YEDVEELRLVLG 2209
Cdd:smart00237   79 YEKDETFYVRLS 90
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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