|
Name |
Accession |
Description |
Interval |
E-value |
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
60-788 |
1.67e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 82.41 E-value: 1.67e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 60 LASYESQIAKLRSEVEKGEALRQ------SLEYDLAVAR-KEAGLGRRAAEERLAEAHRIQEKLCAQNSELQAKTNETEK 132
Cdd:TIGR02168 195 LNELERQLKSLERQAEKAERYKElkaelrELELALLVLRlEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 133 AFQtsqqKWKEECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEKTLQEALEkhQREKNEMESHIRETALEEFRLQEEQ 212
Cdd:TIGR02168 275 EVS----ELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEA--QLEELESKLDELAEELAELEEKLEE 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 213 WEAERRELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEAERA 292
Cdd:TIGR02168 349 LKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK 428
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 293 AHLESKFnsEIIQLRIRDLEGALQVEKASQAEAVADLEIIKNEFKEVESAYEREKHNAQESFAKLNLLE-----KEYFSK 367
Cdd:TIGR02168 429 KLEEAEL--KELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLErlqenLEGFSE 506
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 368 NKKLNEDIEEQKKVIID-------------------LSKRLQY----NEKSCSELQEELVMAKKHQAFLVETCENNVKEL 424
Cdd:TIGR02168 507 GVKALLKNQSGLSGILGvlselisvdegyeaaieaaLGGRLQAvvveNLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEI 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 425 ESILDSFTVSGQWTSGIHKDKDK-PPSFSVVLE-RLRRTL--TDYQNKLEDASN------------------------EE 476
Cdd:TIGR02168 587 QGNDREILKNIEGFLGVAKDLVKfDPKLRKALSyLLGGVLvvDDLDNALELAKKlrpgyrivtldgdlvrpggvitggSA 666
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 477 KACNELDSTKQKIDSHTKNIK-------ELQDKLADVNKELSHLHTKCADREAL---ISTLKVELQNVLHCWEKEKAQAA 546
Cdd:TIGR02168 667 KTNSSILERRREIEELEEKIEeleekiaELEKALAELRKELEELEEELEQLRKEleeLSRQISALRKDLARLEAEVEQLE 746
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 547 QSESELQKLSQAFHKDAEEKLTFLHTLYQHLVAGCVLIKQPEGMLDKFswSELCAVLQENVDALIADLNRANEKIRHLEY 626
Cdd:TIGR02168 747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQL--KEELKALREALDELRAELTLLNEEAANLRE 824
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 627 ICKNKSDTMRELQQTQEDTftkvaeqikaqescwHRQKKELELQyselflevqkraqkfQEIAEKNMEKLN-HIEKSHEQ 705
Cdd:TIGR02168 825 RLESLERRIAATERRLEDL---------------EEQIEELSED---------------IESLAAEIEELEeLIEELESE 874
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 706 LVlensHFKKLLSQTQREQMSLLAACALMAGALYPLYSRSCALSTQRDFLQEQVNTFEL----FKLEIRTLAQALSTVEE 781
Cdd:TIGR02168 875 LE----ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELrlegLEVRIDNLQERLSEEYS 950
|
....*..
gi 38348729 782 KKQEEAK 788
Cdd:TIGR02168 951 LTLEEAE 957
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
64-378 |
1.17e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 66.11 E-value: 1.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 64 ESQIAKLRSEVEKgeALR-QSLEYDLAvarkeaglgRRAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAfQTSQQKWK 142
Cdd:COG1196 199 ERQLEPLERQAEK--AERyRELKEELK---------ELEAELLLLKLRELEAELEELEAELEELEAELEEL-EAELAELE 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 143 EECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEKTLQEALEKHQREKNEmeshiretaLEEFRLQEEQWEAERRELQF 222
Cdd:COG1196 267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER---------LEELEEELAELEEELEELEE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 223 IVQEQDTAVQNMHKKVEKLETEhmdcsdLLRRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEAE-RAAHLESKfnS 301
Cdd:COG1196 338 ELEELEEELEEAEEELEEAEAE------LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAaQLEELEEA--E 409
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 38348729 302 EIIQLRIRDLEGALQVEKASQAEAVADLEIIKNEFKEVESAYEREKHNAQESFAKLNLLEKEYFSKNKKLNEDIEEQ 378
Cdd:COG1196 410 EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
68-377 |
9.81e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 63.55 E-value: 9.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 68 AKLRSEVEKGEALRQSLEYDLAVARKEaglgRRAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAFQTSQQKWKEecrr 147
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKRELSSLQSE----LRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEE---- 741
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 148 FEHDLEERDNMIQNCNREYDLLMKEKSRLEKTL---QEALEkhqreknEMESHIRETALEEFRLQEEQWEAERRELQFIV 224
Cdd:TIGR02169 742 LEEDLSSLEQEIENVKSELKELEARIEELEEDLhklEEALN-------DLEARLSHSRIPEIQAELSKLEEEVSRIEARL 814
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 225 QEQDTAVQNMHKKVEKLETEHMDcsdlLRRQTSELEfstQREERLRKEFEATTLRVRKLEENIEAeraahleskfnseiI 304
Cdd:TIGR02169 815 REIEQKLNRLTLEKEYLEKEIQE----LQEQRIDLK---EQIKSIEKEIENLNGKKEELEEELEE--------------L 873
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 38348729 305 QLRIRDLEGALQVEKASQAEAVADLEIIKNEFKEVESAYEREKHNAQESFAKLNLLEKEYFSKNKKLNEDIEE 377
Cdd:TIGR02169 874 EAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEI 946
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
164-430 |
2.65e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.88 E-value: 2.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 164 REYDLLMKEKSRLEKTL-----QEALEKHQREKNEMESHirETALEEFRLQEEQWEAERRELQFIVQEQDTAVQNMHKKV 238
Cdd:COG1196 213 ERYRELKEELKELEAELlllklRELEAELEELEAELEEL--EAELEELEAELAELEAELEELRLELEELELELEEAQAEE 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 239 EKLETEHMDCSDLLRRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHLESKFNSEIIQLRIRDLEGALQVE 318
Cdd:COG1196 291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 319 KASQAEAVADLEIIKNEFKEVESA---YEREKHNAQESFAKLNLLEKEYFSKNKKLNEDIEEQKKVIIDLSKRLQYNEKS 395
Cdd:COG1196 371 EAELAEAEEELEELAEELLEALRAaaeLAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
|
250 260 270
....*....|....*....|....*....|....*
gi 38348729 396 CSELQEELVMAKKHQAFLVETCENNVKELESILDS 430
Cdd:COG1196 451 EAELEEEEEALLELLAELLEEAALLEAALAELLEE 485
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
131-402 |
3.53e-09 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 61.29 E-value: 3.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 131 EKAFQTSQQKWKEECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEKTLQEALEKHQREKNEMEshiRETALEEFRLQE 210
Cdd:pfam17380 281 QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAME---RERELERIRQEE 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 211 EqweaeRRELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQ-TSELEFSTQREERLRK--EFEATTLRVRKLEENI 287
Cdd:pfam17380 358 R-----KRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQElEAARKVKILEEERQRKiqQQKVEMEQIRAEQEEA 432
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 288 EAERAAHLESKFNSEIIQLRIRDLEGALQVEKASQAEA---VADLEIIKNEFKEVESAYEREKHNAQESFA-KLNLLEKE 363
Cdd:pfam17380 433 RQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEerkRKKLELEKEKRDRKRAEEQRRKILEKELEErKQAMIEEE 512
|
250 260 270
....*....|....*....|....*....|....*....
gi 38348729 364 yfSKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEE 402
Cdd:pfam17380 513 --RKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEME 549
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
62-377 |
6.23e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.84 E-value: 6.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 62 SYESQIAKLRSEVEKGEALRQSLEYDLAVARKEAGLGRRAAEERLAEAHRIQEKLCAQNSELQAKTNEtekafqtsQQKW 141
Cdd:TIGR02168 674 ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAE--------VEQL 745
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 142 KEECRRFEHDLEERDNMIqncnreydllMKEKSRLEKtLQEALEKHQREKNEMESHIretalEEFRLQEEQWEAERRELQ 221
Cdd:TIGR02168 746 EERIAQLSKELTELEAEI----------EELEERLEE-AEEELAEAEAEIEELEAQI-----EQLKEELKALREALDELR 809
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 222 FIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEA---------ERA 292
Cdd:TIGR02168 810 AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAllnerasleEAL 889
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 293 AHLESKFNSEIIQLR-----IRDLEGALQVEKASQAEAVADLEIIKNEFKEVESA----YEREKHNAQESFAKLNLLEKE 363
Cdd:TIGR02168 890 ALLRSELEELSEELReleskRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlseeYSLTLEEAEALENKIEDDEEE 969
|
330
....*....|....
gi 38348729 364 YFSKNKKLNEDIEE 377
Cdd:TIGR02168 970 ARRRLKRLENKIKE 983
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
91-431 |
6.49e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.84 E-value: 6.49e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 91 ARKEAGLGRRAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAFQTSQQkwkeecrrfehDLEERDNMIQNCNREYDLLM 170
Cdd:TIGR02168 664 GSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEE-----------ELEQLRKELEELSRQISALR 732
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 171 KEKSRLEKTLQEALEKHQREKNEMESHIRETALEEFRLQEEQW-----EAERRELQFIVQEQDTAVQNMHKKVEKLETEH 245
Cdd:TIGR02168 733 KDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEelaeaEAEIEELEAQIEQLKEELKALREALDELRAEL 812
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 246 MDCSDLLRRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEAeraahleskfnseiiqlrirdLEGALQVEKASQAEA 325
Cdd:TIGR02168 813 TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES---------------------LAAEIEELEELIEEL 871
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 326 VADLEIIKNEFKEVESAYEREKHNAQESFAKLNLLEKEYFSKNKKLNEDIEEQKKVIIDLSK---RLQYNEKSCSELQE- 401
Cdd:TIGR02168 872 ESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGlevRIDNLQERLSEEYSl 951
|
330 340 350
....*....|....*....|....*....|...
gi 38348729 402 ELVMAKKHQAFLV---ETCENNVKELESILDSF 431
Cdd:TIGR02168 952 TLEEAEALENKIEddeEEARRRLKRLENKIKEL 984
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
485-1246 |
4.00e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.14 E-value: 4.00e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 485 TKQKIDSHTKNIKELQDKLADVNKELSHLHT--KCADR-----------------------EALISTLKVELQNVLHCWE 539
Cdd:TIGR02168 177 TERKLERTRENLDRLEDILNELERQLKSLERqaEKAERykelkaelrelelallvlrleelREELEELQEELKEAEEELE 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 540 KEKAQAAQSESELQKLSQAFHKDAEEKLTFLHTLYQHLvagcVLIKQPEGMLdkfswselcAVLQENVDALIADLNRANE 619
Cdd:TIGR02168 257 ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA----NEISRLEQQK---------QILRERLANLERQLEELEA 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 620 KIRHLEyickNKSDTMRE---LQQTQEDTFTKVAEQIKAQESCWHRQKKELELQYSELFLEVQKRAQKFQEI---AEKNM 693
Cdd:TIGR02168 324 QLEELE----SKLDELAEelaELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLelqIASLN 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 694 EKLNHIEKSHEQLvleNSHFKKLLSQTQREQMSLLAAcalmagALYPLYSRSCALSTQRDFLQEQVNTFELFKLEIRTLA 773
Cdd:TIGR02168 400 NEIERLEARLERL---EDRRERLQQEIEELLKKLEEA------ELKELQAELEELEEELEELQEELERLEEALEELREEL 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 774 QALSTVEEKKQEEAKMKKKTFKGLIRIFR------KGVIAVLA-ANRLKILGQSCASLFTWMESFK--------EGIGML 838
Cdd:TIGR02168 471 EEAEQALDAAERELAQLQARLDSLERLQEnlegfsEGVKALLKnQSGLSGILGVLSELISVDEGYEaaieaalgGRLQAV 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 839 VCTGEPQDKhkfpkhqkeqlrclQALSWLTSSDLLAAiisSMAELQDVIGKADPNSR---ICGHLLIGAAKNSFAKLMDK 915
Cdd:TIGR02168 551 VVENLNAAK--------------KAIAFLKQNELGRV---TFLPLDSIKGTEIQGNDreiLKNIEGFLGVAKDLVKFDPK 613
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 916 ISLVMEciPLHSSRSITyvekDSLVQ--RLAHGLHKVNTLALKYG--LRGHVPITKSTASLQKQILGFTQrlhaaevERR 991
Cdd:TIGR02168 614 LRKALS--YLLGGVLVV----DDLDNalELAKKLRPGYRIVTLDGdlVRPGGVITGGSAKTNSSILERRR-------EIE 680
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 992 SLRLEVTEFKRSVNEMKKELDKAQGLQMQL-NEFKQSKLITHE---KFESACEELNNALLREEQAQMLLNEQAQQLQELN 1067
Cdd:TIGR02168 681 ELEEKIEELEEKIAELEKALAELRKELEELeEELEQLRKELEElsrQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 1068 YKLELHSSEEADKNQTLGEAVKSLSEAKMELRRKDQSLRQLNRHLTQLEQDKRRLEENIHDAESALRMAAKDKECVANHM 1147
Cdd:TIGR02168 761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL 840
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 1148 RAVENTLHKVRDQISLswSAASRNDFTLQLPKLHLETFAMEGLKGgpevvACQAMIKSFMDVYQLASTRIMTLEKEMTSH 1227
Cdd:TIGR02168 841 EDLEEQIEELSEDIES--LAAEIEELEELIEELESELEALLNERA-----SLEEALALLRSELEELSEELRELESKRSEL 913
|
810
....*....|....*....
gi 38348729 1228 RSHIAALKSELHTACLREN 1246
Cdd:TIGR02168 914 RRELEELREKLAQLELRLE 932
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
261-558 |
5.38e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.76 E-value: 5.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 261 FSTQRE-ERLRKEFEATTLRVRKLEENIEAERAAHLEskfnseiIQLRIRDLEGALQVEKASQAEAVADLEIIKNEFKEV 339
Cdd:TIGR02168 673 LERRREiEELEEKIEELEEKIAELEKALAELRKELEE-------LEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 340 ESAYEREKHNAQESFAKLNLLEK---EYFSKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEELVMAKKHQAFLVET 416
Cdd:TIGR02168 746 EERIAQLSKELTELEAEIEELEErleEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRER 825
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 417 CENNVKELESILDSFTVSGQWTSGIHKDKDkppSFSVVLERLRRTLTDYQNKLEDASNE--------EKACNELDSTKQK 488
Cdd:TIGR02168 826 LESLERRIAATERRLEDLEEQIEELSEDIE---SLAAEIEELEELIEELESELEALLNErasleealALLRSELEELSEE 902
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 38348729 489 IDSHTKNIKELQDKLADVNKELSHLHTKCADREALISTLK--------VELQNVLHCWEKEKAQAAQSESELQKLSQA 558
Cdd:TIGR02168 903 LRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQerlseeysLTLEEAEALENKIEDDEEEARRRLKRLENK 980
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
134-475 |
5.89e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.39 E-value: 5.89e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 134 FQTSQQKWKEECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEKtlqeaLEKHQREKNEMESHIRETALEEFRLQEEQW 213
Cdd:TIGR02169 168 FDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER-----YQALLKEKREYEGYELLKEKEALERQKEAI 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 214 EAERRELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQTSElefstqREERLRKEFEATTLRVRKLEENI-----E 288
Cdd:TIGR02169 243 ERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE------EQLRVKEKIGELEAEIASLERSIaekerE 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 289 AERAAHLESKFNSEI--IQLRIRDLEGALQVEKASQAEAVADLEIIKNEFKEVESAYEREKHNAQESFAKLnlleKEYFS 366
Cdd:TIGR02169 317 LEDAEERLAKLEAEIdkLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDEL----KDYRE 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 367 KNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEELVMAKKHQAFLVETCENNVKELESIldsftvsGQWTSGIHKDKD 446
Cdd:TIGR02169 393 KLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ-------EWKLEQLAADLS 465
|
330 340
....*....|....*....|....*....
gi 38348729 447 KppsFSVVLERLRRTLTDYQNKLEDASNE 475
Cdd:TIGR02169 466 K---YEQELYDLKEEYDRVEKELSKLQRE 491
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
29-567 |
1.20e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 56.23 E-value: 1.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 29 ETELDITDNLRKKLHWAKKEKLEITTKHN---AELASYESQIAKLRSEVEKGEALRQSLEyDLAVARKEAGLGRRAAEER 105
Cdd:PRK03918 182 EKFIKRTENIEELIKEKEKELEEVLREINeisSELPELREELEKLEKEVKELEELKEEIE-ELEKELESLEGSKRKLEEK 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 106 LAEAHRIQEKLCAQNSELQAKTNETEK---------AFQTSQQKWKEECRRFEHDLEERDNMIQNCNREYDLLMKEKSRL 176
Cdd:PRK03918 261 IRELEERIEELKKEIEELEEKVKELKElkekaeeyiKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERL 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 177 EKtLQEALEKHQREKNEMEShiRETALEEFRLQEEQWEAERRELQFIVQEQdtaVQNMHKKVEKLETEHMDCSDLLRRQT 256
Cdd:PRK03918 341 EE-LKKKLKELEKRLEELEE--RHELYEEAKAKKEELERLKKRLTGLTPEK---LEKELEELEKAKEEIEEEISKITARI 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 257 SELEfstQREERLRKEFEA-------TTLRVRKLEENIEAE--RAAHLE-SKFNSEIIQL--RIRDLEGAL-QVEKA-SQ 322
Cdd:PRK03918 415 GELK---KEIKELKKAIEElkkakgkCPVCGRELTEEHRKEllEEYTAElKRIEKELKEIeeKERKLRKELrELEKVlKK 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 323 AEAVADLEIIKNEFKEVESayEREKHNAQESFAKLNLLE--KEYFSKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQ 400
Cdd:PRK03918 492 ESELIKLKELAEQLKELEE--KLKKYNLEELEKKAEEYEklKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELE 569
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 401 EELVMAKKHQAFL----VETCENNVKELESILDSFTVSGQWTSGIHKDKDKppsfsvvLERLRRTLTDYQNKLEDASNE- 475
Cdd:PRK03918 570 EELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKE-------LKKLEEELDKAFEELAETEKRl 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 476 EKACNELDSTKQKIDShtKNIKELQDKLADVNKELSHLHTKCADREALISTLKVELQNVLHcwEKEKAQAAQSESELQKL 555
Cdd:PRK03918 643 EELRKELEELEKKYSE--EEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKE--ELEEREKAKKELEKLEK 718
|
570
....*....|..
gi 38348729 556 SQAFHKDAEEKL 567
Cdd:PRK03918 719 ALERVEELREKV 730
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
22-503 |
7.31e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 53.99 E-value: 7.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 22 VKQILKNETELDITDNLRKKLHWAKKEkleittkhnAELASYESQIAKLRSEVEKGEALRQSLEYDLAVARKEAGLGRRA 101
Cdd:PTZ00121 1304 ADEAKKKAEEAKKADEAKKKAEEAKKK---------ADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE 1374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 102 AEERLAEAHRIQEKLCAQNSELQAKTNETEKafQTSQQKWKEECRRFEHDLEERDNMIQNCNrEYDLLMKEKSRLEKTLQ 181
Cdd:PTZ00121 1375 EAKKKADAAKKKAEEKKKADEAKKKAEEDKK--KADELKKAAAAKKKADEAKKKAEEKKKAD-EAKKKAEEAKKADEAKK 1451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 182 EALEKHQREKNEMESHIRETALEEFRLQEEQWEAErrELQFIVQEQDTAVQNMHKKVE-KLETEHMDCSDLLRR--QTSE 258
Cdd:PTZ00121 1452 KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKAD--EAKKKAEEAKKKADEAKKAAEaKKKADEAKKAEEAKKadEAKK 1529
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 259 LEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHLESKFNSEIIQ-LRIRDLEGALQVEKASQAEAVADLEIIKNEFK 337
Cdd:PTZ00121 1530 AEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKnMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 338 EVESAYEREKHNAQE---------SFAKLNLLEKEYFSKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEELVMAKK 408
Cdd:PTZ00121 1610 EEAKKAEEAKIKAEElkkaeeekkKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK 1689
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 409 HQAFLVETCENNvKELESILDSFTVSGQWTSGIHKDKDKPpsfSVVLERLRRTLTDYQNKLEDASNEEKACNELDSTKQK 488
Cdd:PTZ00121 1690 AAEALKKEAEEA-KKAEELKKKEAEEKKKAEELKKAEEEN---KIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKE 1765
|
490
....*....|....*
gi 38348729 489 IDSHTKNIKELQDKL 503
Cdd:PTZ00121 1766 EEKKAEEIRKEKEAV 1780
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
173-513 |
3.47e-06 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 51.43 E-value: 3.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 173 KSRLEKTLQEALEKHQreKNEMESHIRETALEEFRLQEEQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLl 252
Cdd:pfam07888 33 QNRLEECLQERAELLQ--AQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSAS- 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 253 rrqtseLEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHLESKFNSEIIQLRIRDLEGALQVEKASQAEAVADLEII 332
Cdd:pfam07888 110 ------SEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQT 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 333 KNEFKEVESAYEREKHNAQESFAKLNLLEKEYFSKNKKLNE------DIEEQKKVIIDLSKRLQYNEKSCSELQEEL--- 403
Cdd:pfam07888 184 EEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTahrkeaENEALLEELRSLQERLNASERKVEGLGEELssm 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 404 ------VMAKKHQAFLvETCENNVKELESILDSFTVSGQWTS-------GIHKDKDKPPSFSVVLERLRRTLTdyqnklE 470
Cdd:pfam07888 264 aaqrdrTQAELHQARL-QAAQLTLQLADASLALREGRARWAQeretlqqSAEADKDRIEKLSAELQRLEERLQ------E 336
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 38348729 471 DASNEEKACNEL----DSTKQKIDSHTKNIKELQDKLADVNKELSHL 513
Cdd:pfam07888 337 ERMEREKLEVELgrekDCNRVQLSESRRELQELKASLRVAQKEKEQL 383
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
54-291 |
3.95e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.48 E-value: 3.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 54 TKHNAELASYESQIAKLRSEVEKGEALRQSLE---YDLAVARKEAGLGRRAAEERLAEAHRIQEKLCAQNSELQAKTNET 130
Cdd:COG1196 284 EEAQAEEYELLAELARLEQDIARLEERRRELEerlEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 131 EKAFQTSQQKWKEECRRFEHDLEERDNMIQNCNREYDLLmKEKSRLEKTLQEALEKHQREKNEMESHIRETALEefRLQE 210
Cdd:COG1196 364 EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL-EELEEAEEALLERLERLEEELEELEEALAELEEE--EEEE 440
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 211 EQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEAE 290
Cdd:COG1196 441 EEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR 520
|
.
gi 38348729 291 R 291
Cdd:COG1196 521 G 521
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
36-566 |
4.19e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 51.68 E-value: 4.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 36 DNLRKKLHWAKKEKLEITTKHNAELASYESQIAKLRSEVEKGEALRQSLEYDLAVARKEAGLGRRAAEERLAEAHRIQEK 115
Cdd:PTZ00121 1233 EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAE 1312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 116 LCAQNSELQAKTNETEKAFQTSQQKWKE-----ECRRFEHDLEERDNMIQNCNREYDLLMKEKSRL----------EKTL 180
Cdd:PTZ00121 1313 EAKKADEAKKKAEEAKKKADAAKKKAEEakkaaEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKkadaakkkaeEKKK 1392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 181 QEALEKHQREKNEMESHIRETALEEFRLQEEQWEAERR----ELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQT 256
Cdd:PTZ00121 1393 ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKkkadEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA 1472
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 257 SELEFSTQ---REERLRKEFEATTLRVRKLEENIEAERAAHLESKFNSEIIQLRIRDLEGALQVEKASQAEAVADLEIIK 333
Cdd:PTZ00121 1473 DEAKKKAEeakKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK 1552
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 334 N--------EFKEVESAyEREKHNAQESFAKLNLLEKEYFSKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEELVM 405
Cdd:PTZ00121 1553 KaeelkkaeEKKKAEEA-KKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEE 1631
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 406 AKKHQAfLVETCENNVKELESIldsftvsgqwtsgihkdKDKPPSFSVVLERLRRTLTDYQNKLEDASNEEKACNELDST 485
Cdd:PTZ00121 1632 KKKVEQ-LKKKEAEEKKKAEEL-----------------KKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEA 1693
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 486 KQKIDSHTKNIKELQDKLADVNKELSHLHTKCADREALISTLKVELQNvlhcwEKEKAQAAQSESELQKLSQAFHKDAEE 565
Cdd:PTZ00121 1694 LKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE-----DKKKAEEAKKDEEEKKKIAHLKKEEEK 1768
|
.
gi 38348729 566 K 566
Cdd:PTZ00121 1769 K 1769
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
23-509 |
6.07e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.91 E-value: 6.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 23 KQILKNETELDITDNLRKKLHWAKK----EKLEITTKHNAELASYESQIAKLRSEVEKGEALRQSLEYDLAVARKEAGLG 98
Cdd:PTZ00121 1460 EEAKKKAEEAKKADEAKKKAEEAKKadeaKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEA 1539
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 99 RRAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAFQTSQQKWKEECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEK 178
Cdd:PTZ00121 1540 KKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK 1619
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 179 TLQEALEKHQREKNEMESHIRETAlEEFRLQEEQWEAERRELQFIVQEQDTAVQNMHKKVE--KLETEHMDCSDLLRRQT 256
Cdd:PTZ00121 1620 IKAEELKKAEEEKKKVEQLKKKEA-EEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEakKAEEDEKKAAEALKKEA 1698
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 257 SElefsTQREERLRKEFEAttlRVRKLEENIEAEraahleskfnsEIIQLRIRDLEGALQVEKASQAEAVADlEIIKNEF 336
Cdd:PTZ00121 1699 EE----AKKAEELKKKEAE---EKKKAEELKKAE-----------EENKIKAEEAKKEAEEDKKKAEEAKKD-EEEKKKI 1759
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 337 KEVESayEREKHNAQESFAKLNLLEKEYFSKNKKLNEDIEEQKKVIIDLSKRLQYNEKS----CSELQEELVMAKKHQAF 412
Cdd:PTZ00121 1760 AHLKK--EEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEgnlvINDSKEMEDSAIKEVAD 1837
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 413 LVETCENNVKELESILDSF----TVSGQWTSGIHKDKDKPPSFSVVLERLRRTLTDYQNKLE-DASNEEKACNELDSTKQ 487
Cdd:PTZ00121 1838 SKNMQLEEADAFEKHKFNKnnenGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIErEIPNNNMAGKNNDIIDD 1917
|
490 500
....*....|....*....|....*
gi 38348729 488 KIDSH---TKNIKELQDKLADVNKE 509
Cdd:PTZ00121 1918 KLDKDeyiKRDAEETREEIIKISKK 1942
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
88-516 |
6.79e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.83 E-value: 6.79e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 88 LAVARKEAGLGRRAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAFQTSQQKWKE--ECRRFEHDLEERDNMIQNCNRE 165
Cdd:PRK03918 167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREEleKLEKEVKELEELKEEIEELEKE 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 166 YDLLMKEKSRLEKTLQEaLEKHQREKnemESHIRETALEEFRLQEEQWEAER-RELQFIVQEQDTAVQNMHKKVEKLETE 244
Cdd:PRK03918 247 LESLEGSKRKLEEKIRE-LEERIEEL---KKEIEELEEKVKELKELKEKAEEyIKLSEFYEEYLDELREIEKRLSRLEEE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 245 hmdcSDLLRRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEA-ERAAHLESKFNseiiqlRIRDLEGALQVEKasqa 323
Cdd:PRK03918 323 ----INGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELyEEAKAKKEELE------RLKKRLTGLTPEK---- 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 324 eavadleiIKNEFKEVESAYEREKHNAQESFAKLNLLEKEYFSKNKKLNE----------------------DIEEQKKV 381
Cdd:PRK03918 389 --------LEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEElkkakgkcpvcgrelteehrkeLLEEYTAE 460
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 382 IIDLSKRLQYNEKSCSELQEELV-----MAKKHQAFLVETCENNVKELESILDSFTvsgqwtsgihkdkdkppsfsvvLE 456
Cdd:PRK03918 461 LKRIEKELKEIEEKERKLRKELRelekvLKKESELIKLKELAEQLKELEEKLKKYN----------------------LE 518
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 457 RLRRTLTDYQNKLEDASNEEKACNELDSTKQKIDSHTKNIKELQDKLADVNKELSHLHTK 516
Cdd:PRK03918 519 ELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKE 578
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
171-790 |
7.58e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.45 E-value: 7.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 171 KEKSRLEKTLQEALEKHQREKNEMESHIREtaLEEFRLQEEQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEhmdcsd 250
Cdd:PRK03918 210 NEISSELPELREELEKLEKEVKELEELKEE--IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEK------ 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 251 llRRQTSELEFSTQREERLRKEFEATTLRVRKLEEnieaeRAAHLESKFNSeiIQLRIRDLEgalqvekasqaEAVADLE 330
Cdd:PRK03918 282 --VKELKELKEKAEEYIKLSEFYEEYLDELREIEK-----RLSRLEEEING--IEERIKELE-----------EKEERLE 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 331 IIKNEFKEVESAYEREKHNA---QESFAKLNLLEKeyfSKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEELVMAK 407
Cdd:PRK03918 342 ELKKKLKELEKRLEELEERHelyEEAKAKKEELER---LKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELK 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 408 KHQAFLvetcENNVKELEsildsftvsgqwtsgihKDKDKPPSfsvvlerLRRTLTdyqnkledasnEEKACNELDSTKQ 487
Cdd:PRK03918 419 KEIKEL----KKAIEELK-----------------KAKGKCPV-------CGRELT-----------EEHRKELLEEYTA 459
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 488 KIDSHTKNIKELQDKLADVNKELSHLHTKCADREALIstlkvelqnvlhcweKEKAQAAQSESELQKLSQAFHKDAEEKL 567
Cdd:PRK03918 460 ELKRIEKELKEIEEKERKLRKELRELEKVLKKESELI---------------KLKELAEQLKELEEKLKKYNLEELEKKA 524
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 568 TFLHTLYQHLVAgcvLIKQPEGMLDKFswselcavlqENVDALIADLNRANEKIRHLEyicKNKSDTMRELQQTQEDTFT 647
Cdd:PRK03918 525 EEYEKLKEKLIK---LKGEIKSLKKEL----------EKLEELKKKLAELEKKLDELE---EELAELLKELEELGFESVE 588
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 648 KVAEQIKAQESCWhrqKKELELQYSELFLEV-QKRAQKFQEIAEKNMEKLNHIEKSHEQLVLENSHFKKLLSQTQ----- 721
Cdd:PRK03918 589 ELEERLKELEPFY---NEYLELKDAEKELEReEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEyeelr 665
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 38348729 722 REQMSLLAACALMAGALYPLYSRSCALSTQRDFLQEQVNTFELFKLEIRTLAQALSTVEEKKQEEAKMK 790
Cdd:PRK03918 666 EEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYK 734
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
100-622 |
7.82e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 50.68 E-value: 7.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 100 RAAEERLAEAHRIQEKLCAQNSELQAKTNETEKA-FQTSQQKWKEECRRFEHDLEERDNMIQNCNREYDLLMKEKS---- 174
Cdd:COG4913 258 RELAERYAAARERLAELEYLRAALRLWFAQRRLElLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRgngg 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 175 RLEKTLQEALEKHQREKNEMEsHIRETALEEFRLQEEQWEAERRELQfivqeqdTAVQNMHKKVEKLETEHMDCSDLLRR 254
Cdd:COG4913 338 DRLEQLEREIERLERELEERE-RRRARLEALLAALGLPLPASAEEFA-------ALRAEAAALLEALEEELEALEEALAE 409
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 255 QTSELEFSTQREERLRKEFEAttLRVRKLeeNIEAeraahleskfnsEIIQLRiRDLEGALQVeKASQAEAVADLEIIKN 334
Cdd:COG4913 410 AEAALRDLRRELRELEAEIAS--LERRKS--NIPA------------RLLALR-DALAEALGL-DEAELPFVGELIEVRP 471
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 335 EFKEVESAYEREKHNaqesfAKLNLL-EKEYFSK-------NK--------KLNEDIEEQKKVIID---LSKRLQYNEKS 395
Cdd:COG4913 472 EEERWRGAIERVLGG-----FALTLLvPPEHYAAalrwvnrLHlrgrlvyeRVRTGLPDPERPRLDpdsLAGKLDFKPHP 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 396 CSE-LQEELvmakkHQAFLVETCEnNVKELESILDSFTVSGQ----WTSGIHKDKDKPPSFSVV--------------LE 456
Cdd:COG4913 547 FRAwLEAEL-----GRRFDYVCVD-SPEELRRHPRAITRAGQvkgnGTRHEKDDRRRIRSRYVLgfdnraklaaleaeLA 620
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 457 RLRRTLTDYQNKLEDASNEEKACNELDSTKQKIDSHT---KNIKELQDKLADVNKELSHLHTKCADREAL---ISTLKVE 530
Cdd:COG4913 621 ELEEELAEAEERLEALEAELDALQERREALQRLAEYSwdeIDVASAEREIAELEAELERLDASSDDLAALeeqLEELEAE 700
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 531 LQNVlhcwEKEKAQAAQSESELQKLsqafHKDAEEKLTFLHTLYQHLVAGCV------LIKQPEGMLDKFSWSELCAVLQ 604
Cdd:COG4913 701 LEEL----EEELDELKGEIGRLEKE----LEQAEEELDELQDRLEAAEDLARlelralLEERFAAALGDAVERELRENLE 772
|
570
....*....|....*...
gi 38348729 605 ENVDALIADLNRANEKIR 622
Cdd:COG4913 773 ERIDALRARLNRAEEELE 790
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
295-545 |
7.90e-06 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 50.31 E-value: 7.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 295 LESKFNSEIIQLRIRDLEGALQVEKASQAEAVADLEIIKNEFKEVESAyerekhnAQESFAKLNLLEKEYFSKNKKLNEd 374
Cdd:PRK05771 40 LSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEEL-------IKDVEEELEKIEKEIKELEEEISE- 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 375 IEEQKKVIIDLSKRLQYNEKSCSELQEELvmAKKH-QAFLVETCENNVKELESILDSFTVsgqwtSGIHKDKDKPPSFSV 453
Cdd:PRK05771 112 LENEIKELEQEIERLEPWGNFDLDLSLLL--GFKYvSVFVGTVPEDKLEELKLESDVENV-----EYISTDKGYVYVVVV 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 454 VLERLrrtLTDYQNKLEDASNEEKACNELDSTKQKIDSHTKNIKELQDKLADVNKELSHLHTKCADreaLISTLKVELQN 533
Cdd:PRK05771 185 VLKEL---SDEVEEELKKLGFERLELEEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLE---ELLALYEYLEI 258
|
250
....*....|..
gi 38348729 534 vlhcwEKEKAQA 545
Cdd:PRK05771 259 -----ELERAEA 265
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
970-1141 |
2.06e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 49.16 E-value: 2.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 970 ASLQKQILGFTQRLHAAEVERRSLRLEVTEFKRSVNEMKKELDKAQGlqmQLNEFKQSKLITHEKFESACEELNNALLRE 1049
Cdd:COG1196 242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQA---EEYELLAELARLEQDIARLEERRRELEERL 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 1050 EQAQM----LLNEQA---QQLQELNYKLELHSSEEADKNQTLGEAVKSLSEAKMELRRKDQSLRQLNRHLTQLEQDKRRL 1122
Cdd:COG1196 319 EELEEelaeLEEELEeleEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAEL 398
|
170
....*....|....*....
gi 38348729 1123 EENIHDAESALRMAAKDKE 1141
Cdd:COG1196 399 AAQLEELEEAEEALLERLE 417
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
46-284 |
2.06e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 49.27 E-value: 2.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 46 KKEKLEittkhnAELASYESQIAKLRSEVEKGEALRQsleydlAVARKEAGLGRR-AAEERLAEAH-RIQEK------LC 117
Cdd:PRK02224 476 RVEELE------AELEDLEEEVEEVEERLERAEDLVE------AEDRIERLEERReDLEELIAERReTIEEKreraeeLR 543
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 118 AQNSELQAKTNETEKAFQTSQQKwKEECRR----FEHDLEERDNMIQNCNREYDLLmKEKSRLEKTLQEALEKHQrEKNE 193
Cdd:PRK02224 544 ERAAELEAEAEEKREAAAEAEEE-AEEAREevaeLNSKLAELKERIESLERIRTLL-AAIADAEDEIERLREKRE-ALAE 620
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 194 MESHIRETaLEEFR-----LQEEQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEHmdcsDLLRRQTSELEFSTQREER 268
Cdd:PRK02224 621 LNDERRER-LAEKRerkreLEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREER----DDLQAEIGAVENELEELEE 695
|
250
....*....|....*.
gi 38348729 269 LRKEFEATTLRVRKLE 284
Cdd:PRK02224 696 LRERREALENRVEALE 711
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
23-537 |
2.87e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 48.89 E-value: 2.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 23 KQILKNETELDItdnLRKKLHWAKKEKL-EITTKHNAELASYESQIAKLRSEVEKGEALRQSLeydlavARKEAGLGRRA 101
Cdd:TIGR00606 279 KQMEKDNSELEL---KMEKVFQGTDEQLnDLYHNHQRTVREKERELVDCQRELEKLNKERRLL------NQEKTELLVEQ 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 102 AEERLaEAHRIQEKLCAQNSELQAKTNETEkafqtsqqkwkeeCRRFEHDLE---ERDNMIQNCNREYDLLMKEKSRLEK 178
Cdd:TIGR00606 350 GRLQL-QADRHQEHIRARDSLIQSLATRLE-------------LDGFERGPFserQIKNFHTLVIERQEDEAKTAAQLCA 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 179 TLQEALEKHQREKNEMESHIRETAlEEFRLQEEQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQTSE 258
Cdd:TIGR00606 416 DLQSKERLKQEQADEIRDEKKGLG-RTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNS 494
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 259 LEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHLESKFNSEIIQL-------RIRDLEGALQVEKASQAEAVADLEI 331
Cdd:TIGR00606 495 LTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKdkmdkdeQIRKIKSRHSDELTSLLGYFPNKKQ 574
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 332 IKNEFKEVEsayeREKHNAQESFAKLNLLEKEYFSKNKKLNEDIEEQKKVIIDLSKRL------QYNEKSCSELQEELVM 405
Cdd:TIGR00606 575 LEDWLHSKS----KEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsQDEESDLERLKEEIEK 650
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 406 AKKHQAFLVETCENNVKELESILDSFTVSGQWTSGIHKDKDKPPSFSVVLERLRRTLTDYQNKLE-DASNEEKACNEL-- 482
Cdd:TIGR00606 651 SSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTEsELKKKEKRRDEMlg 730
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 38348729 483 --DSTKQKIDSHTKNIKELQDKLADVNKELSHLHTKCADREALISTLKVELQNVLHC 537
Cdd:TIGR00606 731 laPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVC 787
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
60-316 |
3.41e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 48.37 E-value: 3.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 60 LASYESQIAKLRSEVEKGEALRQSLEydlavARKEAGLGRRAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAFQTSQq 139
Cdd:COG4913 612 LAALEAELAELEEELAEAEERLEALE-----AELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSD- 685
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 140 kwkeECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEKTLQEALEKHQR------EKNEMESHIRETALEEFRLQEEQW 213
Cdd:COG4913 686 ----DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDElqdrleAAEDLARLELRALLEERFAAALGD 761
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 214 EAERRELQFIVQEQDTAVQNMHKKVEKLETE--------HMDCSDLlrrqTSELEFSTQREERLRK-------EFEAttl 278
Cdd:COG4913 762 AVERELRENLEERIDALRARLNRAEEELERAmrafnrewPAETADL----DADLESLPEYLALLDRleedglpEYEE--- 834
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 38348729 279 RVRK-LEENIEAERaAHLESKFNSEI--IQLRIRDLEGALQ 316
Cdd:COG4913 835 RFKElLNENSIEFV-ADLLSKLRRAIreIKERIDPLNDSLK 874
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
103-560 |
4.59e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.84 E-value: 4.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 103 EERLAEAHRIQEKLCAQNSELQAKTNETEKAFQTSQQKWKEECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEKTLQE 182
Cdd:COG4717 48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 183 ALEKHQREKNEMESHIRETALEEFRLQEEQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEHmdcSDLLRRQTSELEFS 262
Cdd:COG4717 128 LPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLAT---EEELQDLAEELEEL 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 263 TQREERLRKEFEATTLRVRKLEENIEAERAAHLESKFNSEIIQLRIRDLEGALQVEKASQAEAVADLEIIKNEF------ 336
Cdd:COG4717 205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVlflvlg 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 337 --KEVESAYEREKHNAQESFAKLNLLEKEYFSKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEELVMAKKHQAFLv 414
Cdd:COG4717 285 llALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL- 363
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 415 eTCENNVKELESILDSFTVSG--QWTSGIHKDKDKppsfsvvlERLRRTLTDYQNKLEDASNEEKAcnelDSTKQKIDSH 492
Cdd:COG4717 364 -QLEELEQEIAALLAEAGVEDeeELRAALEQAEEY--------QELKEELEELEEQLEELLGELEE----LLEALDEEEL 430
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 493 TKNIKELQDKLADVNKELSHLHTKCADREALISTLK--VELQNVLHCWEKEKAQAAQSESELQKLSQAFH 560
Cdd:COG4717 431 EEELEELEEELEELEEELEELREELAELEAELEQLEedGELAELLQELEELKAELRELAEEWAALKLALE 500
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
472-691 |
5.20e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.07 E-value: 5.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 472 ASNEEKACNELDSTKQKIDSHTKNIKELQDKLADVNKELSHLHTKCADREALISTLKVELQNVlhcwEKEKAQAAQSESE 551
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAAL----EAELAELEKEIAE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 552 LQKLSQAFHKDAEEKLTFLHTLYQHlvAGCVLIKQPEGMLDKFSWSELCAVLQENVDALIADLNRANEKIRHLEYICKNK 631
Cdd:COG4942 95 LRAELEAQKEELAELLRALYRLGRQ--PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 632 SDTMRELQQTQEDTFTKVAEQIKAQESCWHRQKKELELQYSELfLEVQKRAQKFQEIAEK 691
Cdd:COG4942 173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAEL-AELQQEAEELEALIAR 231
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
11-348 |
9.24e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 46.96 E-value: 9.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 11 DTQRLKIASLDvKQILKNETELDITDNLRKKLHWAKKEKLEITTKHNAELASYESQIAKLRSEVEKGEALR--------- 81
Cdd:PRK02224 380 EDRREEIEELE-EEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLeagkcpecg 458
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 82 QSLEYDLAVARKEaglgrrAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAfqtsqqkwKEECRRFEHDLEERDNMIQn 161
Cdd:PRK02224 459 QPVEGSPHVETIE------EDRERVEELEAELEDLEEEVEEVEERLERAEDL--------VEAEDRIERLEERREDLEE- 523
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 162 cnreydLLMKEKSRLEKTlQEALEKHQREKNEMESHIRETAlEEFRLQEEQWEAERRELQFIVQEQdTAVQNMHKKVEKL 241
Cdd:PRK02224 524 ------LIAERRETIEEK-RERAEELRERAAELEAEAEEKR-EAAAEAEEEAEEAREEVAELNSKL-AELKERIESLERI 594
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 242 ETEHMDCSDL------LRRQTSEL-EFSTQREERLRKEFEattlRVRKLEENIEAERAAHLESKfnSEIIQLRIRDLEGA 314
Cdd:PRK02224 595 RTLLAAIADAedeierLREKREALaELNDERRERLAEKRE----RKRELEAEFDEARIEEARED--KERAEEYLEQVEEK 668
|
330 340 350
....*....|....*....|....*....|....
gi 38348729 315 LQVEKASQAEAVADLEIIKNEFKEVESAYEREKH 348
Cdd:PRK02224 669 LDELREERDDLQAEIGAVENELEELEELRERREA 702
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
50-336 |
9.28e-05 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 46.60 E-value: 9.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 50 LEITTKHNAELasyESQIAKLRSEVEKGEALRQSLEYDLAVARKEAGLgrraAEERLAEAHRIQEKLCAQNSELQAKTNE 129
Cdd:pfam19220 127 LAAETEQNRAL---EEENKALREEAQAAEKALQRAEGELATARERLAL----LEQENRRLQALSEEQAAELAELTRRLAE 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 130 TEKAFQTSQQKWKEECRRFEHDLEERdnmiqncnreydllmkekSRLEKTLQEALEKHQREKNEM-----ESHIRETALE 204
Cdd:pfam19220 200 LETQLDATRARLRALEGQLAAEQAER------------------ERAEAQLEEAVEAHRAERASLrmkleALTARAAATE 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 205 EF---------RLQEEQWEAERRELQFIVqEQDTAvqnmHKKVEKLETEHMDcsdlLRRQTSELEFS----TQREERLRK 271
Cdd:pfam19220 262 QLlaearnqlrDRDEAIRAAERRLKEASI-ERDTL----ERRLAGLEADLER----RTQQFQEMQRAraelEERAEMLTK 332
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 38348729 272 EFEATTLRVRKLEENIEA--ERAAHLESKFNSEIIQL--RIRDLEGALQVEKASQAEAVADLEIIKNEF 336
Cdd:pfam19220 333 ALAAKDAALERAEERIASlsDRIAELTKRFEVERAALeqANRRLKEELQRERAERALAQGALEIARESR 401
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
62-408 |
1.09e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.06 E-value: 1.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 62 SYESQIAKLRSEVEKGEALRQSLEYDLAVARKEAGLGRRAAEERLAEAHRIQEKlcAQNSELQAKTNETEKafQTSQQKW 141
Cdd:PTZ00121 1169 ARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAED--AKKAEAVKKAEEAKK--DAEEAKK 1244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 142 KEECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEKTLQEALEKHQREKNEMESHIREtALEEFRLQEEQWEAErrELQ 221
Cdd:PTZ00121 1245 AEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKK-ADEAKKKAEEAKKAD--EAK 1321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 222 FIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHlESKFNS 301
Cdd:PTZ00121 1322 KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD-EAKKKA 1400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 302 EIIQLRIRDLEGALQVEKAS-----QAEAVADLEIIKNEFKEVESAYEREKhNAQESFAKLNLLEK-EYFSKNKKLNEDI 375
Cdd:PTZ00121 1401 EEDKKKADELKKAAAAKKKAdeakkKAEEKKKADEAKKKAEEAKKADEAKK-KAEEAKKAEEAKKKaEEAKKADEAKKKA 1479
|
330 340 350
....*....|....*....|....*....|...
gi 38348729 376 EEQKKViIDLSKRLQYNEKSCSELQEELVMAKK 408
Cdd:PTZ00121 1480 EEAKKA-DEAKKKAEEAKKKADEAKKAAEAKKK 1511
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
47-724 |
1.10e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.98 E-value: 1.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 47 KEKLEITTkhnAELASYESQIAKLRSEVEKGEALRQSLEYDL-AVARKEAGLGRRAAEERLAEAHRIQE--KLCAQNSEL 123
Cdd:TIGR02169 293 KEKIGELE---AEIASLERSIAEKERELEDAEERLAKLEAEIdKLLAEIEELEREIEEERKRRDKLTEEyaELKEELEDL 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 124 QAKTNETEKAFQTSQQKWKEECRRfehdleerdnmIQNCNREYDLLMKEKSRLEKTLQEALEKHQREKNEMEShiRETAL 203
Cdd:TIGR02169 370 RAELEEVDKEFAETRDELKDYREK-----------LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAG--IEAKI 436
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 204 EEFrlqeeqwEAERRELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQTSELefstqreERLRKEFEATTLRVRKL 283
Cdd:TIGR02169 437 NEL-------EEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKEL-------SKLQRELAEAEAQARAS 502
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 284 EENIEAERAAHLESKFNSEIIQLRIRDL-----EGALQVEKAsqAEAVADLEIIKNEFKEVES-AYEREKHNAQESFAKL 357
Cdd:TIGR02169 503 EERVRGGRAVEEVLKASIQGVHGTVAQLgsvgeRYATAIEVA--AGNRLNNVVVEDDAVAKEAiELLKRRKAGRATFLPL 580
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 358 NLLekeyfsKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSE----LQEELVM-----AKKHQA-FLVETCENnvkelesi 427
Cdd:TIGR02169 581 NKM------RDERRDLSILSEDGVIGFAVDLVEFDPKYEPAfkyvFGDTLVVedieaARRLMGkYRMVTLEG-------- 646
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 428 lDSFTVSGQWTSGIHKDKDK---PPSFSVVLERLRRTLTDYQNKLEDASNE-EKACNELDSTKQKIDSHTKNIKELQDKL 503
Cdd:TIGR02169 647 -ELFEKSGAMTGGSRAPRGGilfSRSEPAELQRLRERLEGLKRELSSLQSElRRIENRLDELSQELSDASRKIGEIEKEI 725
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 504 ADVNKELSHLHTKCADREALISTLKVELQNVlhcwekeKAQAAQSESELQKLSQAFHKDAEEkltflhtlyqhlvagcvl 583
Cdd:TIGR02169 726 EQLEQEEEKLKERLEELEEDLSSLEQEIENV-------KSELKELEARIEELEEDLHKLEEA------------------ 780
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 584 IKQPEGMLDKFSWSElcavLQENVDALIADLNRANEKIRHLEYICKNKSdtmRELQQTQEDTFTKVAEQIKAQEscwhrQ 663
Cdd:TIGR02169 781 LNDLEARLSHSRIPE----IQAELSKLEEEVSRIEARLREIEQKLNRLT---LEKEYLEKEIQELQEQRIDLKE-----Q 848
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 38348729 664 KKELELQYSELflevQKRAQKFQEIAEKNMEKLNHIEKSHEQLVLENSHFKKLLSQTQREQ 724
Cdd:TIGR02169 849 IKSIEKEIENL----NGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
457-1133 |
1.13e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 46.59 E-value: 1.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 457 RLRRTLTDYQnKLEDASNE-EKACNELDSTKQKidshTKNIKELQDKLADVNKELSHLHTKCADREalISTLKVELQNVL 535
Cdd:TIGR02168 180 KLERTRENLD-RLEDILNElERQLKSLERQAEK----AERYKELKAELRELELALLVLRLEELREE--LEELQEELKEAE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 536 HCWEKEKAQAAQSESELQKLSQAFHKDAEEKLTFLHTLYQHLVagcvLIKQPEGMLdkfswselcAVLQENVDALIADLN 615
Cdd:TIGR02168 253 EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN----EISRLEQQK---------QILRERLANLERQLE 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 616 RANEKIRHLEyickNKSDTMRE---LQQTQEDTFTKVAEQIKAQESCWHRQKKELELQYSELFLEVQKRAQKFQEI---A 689
Cdd:TIGR02168 320 ELEAQLEELE----SKLDELAEelaELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLelqI 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 690 EKNMEKLNHIEKSHEQLvleNSHFKKLLSQTQREQMSLLAAcalmagALYPLYSRSCALSTQRDFLQEQVNTFELFKLEI 769
Cdd:TIGR02168 396 ASLNNEIERLEARLERL---EDRRERLQQEIEELLKKLEEA------ELKELQAELEELEEELEELQEELERLEEALEEL 466
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 770 RTLAQALSTVEEKKQEEAKMKKKTFKGLIRIFR------KGVIAVLA-ANRLKILGQSCASLFTWMESFK--------EG 834
Cdd:TIGR02168 467 REELEEAEQALDAAERELAQLQARLDSLERLQEnlegfsEGVKALLKnQSGLSGILGVLSELISVDEGYEaaieaalgGR 546
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 835 IGMLVCTGEPQDKhkfpkhqkeqlrclQALSWLTSSDLLAAiisSMAELQDVIGKADPNSR---ICGHLLIGAAKNSFAK 911
Cdd:TIGR02168 547 LQAVVVENLNAAK--------------KAIAFLKQNELGRV---TFLPLDSIKGTEIQGNDreiLKNIEGFLGVAKDLVK 609
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 912 LMDKISLVMECIPLHSSRSITYVEKDSLVQRLAHGLHKV---NTLALKYGL--RGHVPITKSTASLQKQILGFTQRLHAA 986
Cdd:TIGR02168 610 FDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVtldGDLVRPGGVitGGSAKTNSSILERRREIEELEEKIEEL 689
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 987 EVERRSLRLEVTEFKRSVNEMKKELDKAQ----GLQMQLNEFKQSKLITHEKFESACEELNNALLREEQAQMLLNEQAQQ 1062
Cdd:TIGR02168 690 EEKIAELEKALAELRKELEELEEELEQLRkeleELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER 769
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 1063 LQELNYKLELHSSEEADKNQ----------TLGEAVKSLSEAKMELRRKDQSLRQ-----------LNRHLTQLEQDKRR 1121
Cdd:TIGR02168 770 LEEAEEELAEAEAEIEELEAqieqlkeelkALREALDELRAELTLLNEEAANLRErleslerriaaTERRLEDLEEQIEE 849
|
730
....*....|..
gi 38348729 1122 LEENIHDAESAL 1133
Cdd:TIGR02168 850 LSEDIESLAAEI 861
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
70-559 |
1.49e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 46.26 E-value: 1.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 70 LRSEVEKGEALRQSLEYDLAVARKEAGLGRRAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAFQTSQQKWKEECRRFE 149
Cdd:pfam15921 262 LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYE 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 150 HDLEERDNMIQNCNREY-------DLLMKEKSRLEKTLQEAL-EKHQREKN---EMESHIR---------------ETAL 203
Cdd:pfam15921 342 DKIEELEKQLVLANSELtearterDQFSQESGNLDDQLQKLLaDLHKREKElslEKEQNKRlwdrdtgnsitidhlRREL 421
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 204 EEFRLQEEQWEA----ERRELQFIVQEQDTAVQNMHKKVEK---LETEHMDCSDLLRRQTSELEFSTQREERLRKEFEAT 276
Cdd:pfam15921 422 DDRNMEVQRLEAllkaMKSECQGQMERQMAAIQGKNESLEKvssLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDL 501
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 277 TLRVRKLEENIEAERA--AHLESKFNSEIIQLR--------IRDLEGALQVEKASQAEAVADLEIIKNEFKEVESAYERE 346
Cdd:pfam15921 502 TASLQEKERAIEATNAeiTKLRSRVDLKLQELQhlknegdhLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQH 581
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 347 KHNAQESFAKLNLLEKEYFSKNKKLNE-DIEEQKKviidlSKRLQYNEKSCSELQEELVMAKKHQAFLVETCENNVKELE 425
Cdd:pfam15921 582 GRTAGAMQVEKAQLEKEINDRRLELQEfKILKDKK-----DAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERD 656
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 426 SILDSFTVSGQWTSGIHKD--------KDKPPSFSVVLERLRRTLTDYQNKLEDASNEEKAC---------------NEL 482
Cdd:pfam15921 657 QLLNEVKTSRNELNSLSEDyevlkrnfRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMegsdghamkvamgmqKQI 736
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 483 DSTKQKIDSHTKNIKELQDKLADVNKELSHLHTKCADREALISTLKVELQN------VLHCWEKE-KAQAAQSESELQKL 555
Cdd:pfam15921 737 TAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKmageleVLRSQERRlKEKVANMEVALDKA 816
|
....
gi 38348729 556 SQAF 559
Cdd:pfam15921 817 SLQF 820
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
164-721 |
1.49e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 46.67 E-value: 1.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 164 REYDLLMKEKSRLEKTLQEALEKHQREKNEMESHIRETALEEfrlqeeqwEAERRELQFIVQEQDTAVQNMHKKVEKLET 243
Cdd:PTZ00121 1077 KDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAE--------EAKKKAEDARKAEEARKAEDARKAEEARKA 1148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 244 EHMDCSDLLRR--QTSELEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHLESKFNSEiiqlRIRDLEGALQVEKAS 321
Cdd:PTZ00121 1149 EDAKRVEIARKaeDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAE----EERKAEEARKAEDAK 1224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 322 QAEAVADLEIIKnefKEVESAYEREKHNAQESFAKLNLLEKEYFSKN---------------------KKLNEDIEEQKK 380
Cdd:PTZ00121 1225 KAEAVKKAEEAK---KDAEEAKKAEEERNNEEIRKFEEARMAHFARRqaaikaeearkadelkkaeekKKADEAKKAEEK 1301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 381 VIIDLSKRLQYNEKSCSELQEELVMAKKHQAFLVETCENNVKELESIldsftvsgqwTSGIHKDKDKPPSFSVVLERLRR 460
Cdd:PTZ00121 1302 KKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAA----------KAEAEAAADEAEAAEEKAEAAEK 1371
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 461 TLTDYQNKLEDASNEEKACNELDSTKQKIDSHTKNIKELQdKLADVNKELSHLHTKCAD-REALISTLKVElqnvlhcwE 539
Cdd:PTZ00121 1372 KKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELK-KAAAAKKKADEAKKKAEEkKKADEAKKKAE--------E 1442
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 540 KEKAQAAQSESELQKLSQAFHKDAEE--KLTFLHTLYQHLVAGCVLIKQPEGMLDKFSWSELCAVLQENVDaliaDLNRA 617
Cdd:PTZ00121 1443 AKKADEAKKKAEEAKKAEEAKKKAEEakKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKAD----EAKKA 1518
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 618 NEkirhleyicKNKSDTMRELQQTQEDTFTKVAEQIKAQESCwhRQKKELELQYSELFLEVQKRAQKFQEIAEKNMEKLN 697
Cdd:PTZ00121 1519 EE---------AKKADEAKKAEEAKKADEAKKAEEKKKADEL--KKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAK 1587
|
570 580
....*....|....*....|....
gi 38348729 698 HIEKSHEQLVLENSHFKKLLSQTQ 721
Cdd:PTZ00121 1588 KAEEARIEEVMKLYEEEKKMKAEE 1611
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
174-791 |
1.81e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 46.12 E-value: 1.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 174 SRLEKTLQEALEKHQREKNEMESHIRETALEEFRLQEEQWEAER--RELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDL 251
Cdd:pfam02463 165 SRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKalEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 252 LRRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEA---ERAAHLESKFNSEIIQLRIRDlegaLQVEKASQAEAVAD 328
Cdd:pfam02463 245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKlqeEELKLLAKEEEELKSELLKLE----RRKVDDEEKLKESE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 329 LEIIKNEFKEVESAYEREKHNAQESFAKLNLLEKEYFSKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEELVMAKK 408
Cdd:pfam02463 321 KEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELK 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 409 HQafLVETCENNVKELESILDSFTVSGQWTSGIHKDKDKPPSFSVVLERLRRTLTDYQNKLEDASNEEKACNELDstKQK 488
Cdd:pfam02463 401 SE--EEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL--LKE 476
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 489 IDSHTKNIKELQDKLADVNKELSHLHTKCADREALISTLKVELQNVLHCWEKEKAQAAQSESELQKLSQAFHKDAE-EKL 567
Cdd:pfam02463 477 TQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEvSAT 556
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 568 TFLHTLYQHLVAGCVLIKQPEGMLDKFSWSELCAVLQENVDALIADLNRANEKIRHLEYICKNKSDTMRELQ-QTQEDTF 646
Cdd:pfam02463 557 ADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGIlKDTELTK 636
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 647 TKVAEQIKAQESCWHRQKKELELQYSELFLEVQKRAQKFQEIAEKNMEKLNHIEKSHEQLVLENSHFKKlLSQTQREQMS 726
Cdd:pfam02463 637 LKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKE-QREKEELKKL 715
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 38348729 727 LLAACALMAGALYPLYSRScalSTQRDFLQEQVNTFELFKLEIRTlaQALSTVEEKKQEEAKMKK 791
Cdd:pfam02463 716 KLEAEELLADRVQEAQDKI---NEELKLLKQKIDEEEEEEEKSRL--KKEEKEEEKSELSLKEKE 775
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
55-715 |
2.11e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.90 E-value: 2.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 55 KHNAELASYESQIaKLRSEVEKGEALRQSLEYDLAVARKEAGLGRRAAEERLAE-AHRIQEKLCAQNSELQAKTNETEKA 133
Cdd:PTZ00121 1085 EDNRADEATEEAF-GKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEdARKAEEARKAEDAKRVEIARKAEDA 1163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 134 FQTSQQKWKEECRRFEHDLE-------ERDNMIQNCNREYDLLMKEKSRLEKTLQEALEKHQREKNEMESHIRETALEEF 206
Cdd:PTZ00121 1164 RKAEEARKAEDAKKAEAARKaeevrkaEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAK 1243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 207 RLQEEQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQTselefSTQREERLRKEFEATtlrvRKLEEN 286
Cdd:PTZ00121 1244 KAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAD-----EAKKAEEKKKADEAK----KKAEEA 1314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 287 IEAERAAHL--ESKFNSEIIQLRIRDLEGALQVEKASQAEAVADLEIIKNEFKEVESAYEREKHNAQESFAKlnlleKEY 364
Cdd:PTZ00121 1315 KKADEAKKKaeEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK-----AEE 1389
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 365 FSKNKKLNEDIEEQKKVIIDLSKRLQYNEKScselqEELvmakKHQAFLVETCENNVKELESILDSFTVSGQwtsgiHKD 444
Cdd:PTZ00121 1390 KKKADEAKKKAEEDKKKADELKKAAAAKKKA-----DEA----KKKAEEKKKADEAKKKAEEAKKADEAKKK-----AEE 1455
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 445 KDKPPSFSVVLERLRRTlTDYQNKLEDASNEEKACNELDSTKQKIDSHTKniKELQDKLADvnkELSHLHTKCADREALI 524
Cdd:PTZ00121 1456 AKKAEEAKKKAEEAKKA-DEAKKKAEEAKKADEAKKKAEEAKKKADEAKK--AAEAKKKAD---EAKKAEEAKKADEAKK 1529
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 525 STLKVELQNVLHCWEKEKAQAAQSESELQKLSQAfhKDAEEK----------LTFLHTLYQHLVAGCVLIKQPEGMLDKF 594
Cdd:PTZ00121 1530 AEEAKKADEAKKAEEKKKADELKKAEELKKAEEK--KKAEEAkkaeedknmaLRKAEEAKKAEEARIEEVMKLYEEEKKM 1607
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 595 SWSELCAVLQENVDAliADLNRANEKIRHLEYICKNKSDTMR---ELQQTQEDTFTKVAEQIKAQEscwHRQKKELELQY 671
Cdd:PTZ00121 1608 KAEEAKKAEEAKIKA--EELKKAEEEKKKVEQLKKKEAEEKKkaeELKKAEEENKIKAAEEAKKAE---EDKKKAEEAKK 1682
|
650 660 670 680
....*....|....*....|....*....|....*....|....
gi 38348729 672 SElflEVQKRAQKFQEIAEKNMEKLNHIEKSHEQLVLENSHFKK 715
Cdd:PTZ00121 1683 AE---EDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
143-557 |
2.30e-04 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 45.48 E-value: 2.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 143 EECRRFEHDLEER----DNMIQNCNREYDLLMKEKSRLEKTLQEAL--EKHQREKNEMESHIRETALEEFRLQEEQWEAE 216
Cdd:pfam05483 264 EESRDKANQLEEKtklqDENLKELIEKKDHLTKELEDIKMSLQRSMstQKALEEDLQIATKTICQLTEEKEAQMEELNKA 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 217 RRELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQTSELEFSTQREERLRKEFEATTLRVRKLEEnIEAERAAHLE 296
Cdd:pfam05483 344 KAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKK-ILAEDEKLLD 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 297 SKFNSEIIQLRIRDLEGALQVEKASQAEAVADLEIIKNEFKEVESAYEREKHNAQESFAKLNLLEKEYFSKNKKLNEDIE 376
Cdd:pfam05483 423 EKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENK 502
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 377 EQKKVIIDLSKRLQYNEKSCSELQEELVMAKKHQAFLVETCENNVKELESILDSFtvsgqwtsgIHKDKDKPPSFSVVLE 456
Cdd:pfam05483 503 ELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEF---------IQKGDEVKCKLDKSEE 573
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 457 RLRRTLTDYQNKLEDASNEEKACNELdstKQKIDSHTKNIKELQDKLADVNKELSHLHTKCADREALISTLKVELQNVLH 536
Cdd:pfam05483 574 NARSIEYEVLKKEKQMKILENKCNNL---KKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQ 650
|
410 420
....*....|....*....|.
gi 38348729 537 CWEkEKAQAAQSESELQKLSQ 557
Cdd:pfam05483 651 KFE-EIIDNYQKEIEDKKISE 670
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
59-426 |
2.39e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 45.80 E-value: 2.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 59 ELASYESQIAKLRSEVEKGEALRQSLEYDLAVARKEAGLGRRAAEERLAEAhriqeklcaqnsELQAKTNETEKAFQTSQ 138
Cdd:PRK02224 252 ELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEA------------GLDDADAEAVEARREEL 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 139 QKWKEECRRfehDLEERDNMIQNCNREYDLLMKEKSRLEKTLQEALEKHQREKNEMEShiRETALEEFRLQEEQWEAERR 218
Cdd:PRK02224 320 EDRDEELRD---RLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEE--AREAVEDRREEIEELEEEIE 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 219 ELQfivqeqdtavqnmhKKVEKLETEHMDCSDLLRRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHLEsk 298
Cdd:PRK02224 395 ELR--------------ERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECG-- 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 299 fnseiiqlriRDLEGALQVEKASQ-----AEAVADLEIIKNEFKEVESAYEREKhNAQESFAKLNLLEKeyfsKNKKLNE 373
Cdd:PRK02224 459 ----------QPVEGSPHVETIEEdrervEELEAELEDLEEEVEEVEERLERAE-DLVEAEDRIERLEE----RREDLEE 523
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 38348729 374 DIEEQKKVIIDLSKRLQYNEKSCSELQEEL-----VMAKKHQAflVETCENNVKELES 426
Cdd:PRK02224 524 LIAERRETIEEKRERAEELRERAAELEAEAeekreAAAEAEEE--AEEAREEVAELNS 579
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
24-408 |
2.76e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.40 E-value: 2.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 24 QILKNETELDITDNLRKKLHWAKKEKLEITTkhnaELASYESQIAKLRSEVEKGEALRQSLEydlavarkeaglgrraae 103
Cdd:TIGR04523 298 SDLNNQKEQDWNKELKSELKNQEKKLEEIQN----QISQNNKIISQLNEQISQLKKELTNSE------------------ 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 104 erlAEAHRIQEKLCAQNSELQAKTNETEKAFQTSQqKWKEECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEKTLQEA 183
Cdd:TIGR04523 356 ---SENSEKQRELEEKQNEIEKLKKENQSYKQEIK-NLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERL 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 184 LEKHQREKNEMEShiretaLEEfrlQEEQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQTSELEFST 263
Cdd:TIGR04523 432 KETIIKNNSEIKD------LTN---QDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLN 502
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 264 QREERLRKEFEATTLRVRKLEENIEaeraahlesKFNSEI--IQLRIRDLEGalqvekasqaeavadlEIIKNEFKEVES 341
Cdd:TIGR04523 503 EEKKELEEKVKDLTKKISSLKEKIE---------KLESEKkeKESKISDLED----------------ELNKDDFELKKE 557
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 38348729 342 AYEREKHNAQESFAKLNLLEKEYFSKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEELVMAKK 408
Cdd:TIGR04523 558 NLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKK 624
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
20-557 |
3.72e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.01 E-value: 3.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 20 LDVKQILKNETELditdnlrKKLHWAKKEKLEITTKHNAELASYESQIAKLRSEVEKGEALRQSLEYDLAVARKE----- 94
Cdd:TIGR04523 114 NDKEQKNKLEVEL-------NKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEklniq 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 95 -----AGLGRRAAEERLAEAHRIQEK---LCAQNSELQAKTNETEKAFQTSQQKWKEECRRFEHDLEERDNMIQNCNREY 166
Cdd:TIGR04523 187 knidkIKNKLLKLELLLSNLKKKIQKnksLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIK 266
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 167 DLLMKEKSRLEKT------LQEALEKHQREKNEMESHIRETALEEFRLQEEQWEAERRELQFIVQEQDTAVQNMHKKVEK 240
Cdd:TIGR04523 267 KQLSEKQKELEQNnkkikeLEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQ 346
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 241 LETEhmdcsdllrRQTSELEFSTQREERLRKEFEAttlrvrkleENIEAERAAHLESKFNSEIiqlRIRDLEGALQVEKA 320
Cdd:TIGR04523 347 LKKE---------LTNSESENSEKQRELEEKQNEI---------EKLKKENQSYKQEIKNLES---QINDLESKIQNQEK 405
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 321 SQAEAVADLEIIKNEFKEVESAYEREKHNAQESFAKLNLLEKEYFSKN---KKLNEDIEEQKKVIIDLSKRLQYNEKSCS 397
Cdd:TIGR04523 406 LNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKEliiKNLDNTRESLETQLKVLSRSINKIKQNLE 485
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 398 ELQEELVMAKKHQAFLVE---TCENNVKELESILDSFTVS-GQWTSGIHKDKDKPPSFSVVLERLRRTLTDYQNKLEDAS 473
Cdd:TIGR04523 486 QKQKELKSKEKELKKLNEekkELEEKVKDLTKKISSLKEKiEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDE 565
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 474 NEEkacnELDSTKQKIDSHTKNIKELQDKLADVNKELSHLHTKCADREALISTLKVELQNVLHCWEKEKAQAAQSESELQ 553
Cdd:TIGR04523 566 KNK----EIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKN 641
|
....
gi 38348729 554 KLSQ 557
Cdd:TIGR04523 642 KLKQ 645
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
174-565 |
4.35e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.67 E-value: 4.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 174 SRLEKTLQEaLEKHQREKNEMESHIRETALEEFRLQEEQWEAER-RELQFIVQEqdTAVQNMHKKVEKLETEHMDCSDLL 252
Cdd:TIGR02169 170 RKKEKALEE-LEEVEENIERLDLIIDEKRQQLERLRREREKAERyQALLKEKRE--YEGYELLKEKEALERQKEAIERQL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 253 RRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEAEraahleskfnSEIIQLRIRDLEGALQVEKASQAEAVAdleii 332
Cdd:TIGR02169 247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDL----------GEEEQLRVKEKIGELEAEIASLERSIA----- 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 333 knefkevesAYEREKHNAQESFAKLNLLEKEYFSKNKKLNEDIEEQKKVIIDLSKRLQynekscsELQEELvmakkhqaf 412
Cdd:TIGR02169 312 ---------EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYA-------ELKEEL--------- 366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 413 lvetcENNVKELESIldsftvsgqwtsgihkdkdkppsfSVVLERLRRTLTDYQNKLEDasneekacneldsTKQKIDSH 492
Cdd:TIGR02169 367 -----EDLRAELEEV------------------------DKEFAETRDELKDYREKLEK-------------LKREINEL 404
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 38348729 493 TKNIKELQDKLADVNKELSHLHTKCADREALISTLKVELQNVLHCWEKEKAQAAQSESELQKLSQAFHKDAEE 565
Cdd:TIGR02169 405 KRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE 477
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
178-402 |
4.80e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.98 E-value: 4.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 178 KTLQEALEKHQREKNEMESHIRETaleefrlqeeqwEAERRELQFIVQEQDTAVQNMHKKVEKLETEhmdcsdlLRRQTS 257
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAAL------------KKEEKALLKQLAALERRIAALARRIRALEQE-------LAALEA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 258 ELEFSTQREERLRKEFEATTLRVRKLEENIE-AERAAHLESKFNSEIIQLRIRDLEGALQVEKASQAEAvADLEIIKNEF 336
Cdd:COG4942 84 ELAELEKEIAELRAELEAQKEELAELLRALYrLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQA-EELRADLAEL 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 38348729 337 KEVESAYEREKhnaqesfAKLNLLEKEYFSKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEE 402
Cdd:COG4942 163 AALRAELEAER-------AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
23-562 |
5.19e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.52 E-value: 5.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 23 KQILKNETELDITDNLRKKL-HWAKKEKLEI----TTKHNAELASYESQIAKLRSEVEKGEALRQSLEydlaVARKEAGL 97
Cdd:COG4913 262 ERYAAARERLAELEYLRAALrLWFAQRRLELleaeLEELRAELARLEAELERLEARLDALREELDELE----AQIRGNGG 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 98 GR--------RAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAFQTSQQKWKEEcrrfehdLEERDNMIQNCNREYDLL 169
Cdd:COG4913 338 DRleqlereiERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAAL-------LEALEEELEALEEALAEA 410
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 170 MKEKSRlektLQEALEKHQREKNEME---SHIREtALEEFRLQ-EEQWEAERRELQFI-----VQEQDTAVQNmhkKVEK 240
Cdd:COG4913 411 EAALRD----LRRELRELEAEIASLErrkSNIPA-RLLALRDAlAEALGLDEAELPFVgelieVRPEEERWRG---AIER 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 241 letehmdcsdLLRRQTSELEFSTQREERLRKEFEATTLRVR----KLEENIEAERAAHLESKFNSEIIQLRIRDLEGALQ 316
Cdd:COG4913 483 ----------VLGGFALTLLVPPEHYAAALRWVNRLHLRGRlvyeRVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLE 552
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 317 VEKASQAEA--VADLEiiknEFKEVESA----------YEREKHNAQESF-----------AKLNLLEKEYfsknKKLNE 373
Cdd:COG4913 553 AELGRRFDYvcVDSPE----ELRRHPRAitragqvkgnGTRHEKDDRRRIrsryvlgfdnrAKLAALEAEL----AELEE 624
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 374 DIEEQKKVIIDLSKRLQYNEKSCSELQ--EELVMAKKHQAFLVETCENNVKELESILDSftvsgqwtsgihkdkdkppsf 451
Cdd:COG4913 625 ELAEAEERLEALEAELDALQERREALQrlAEYSWDEIDVASAEREIAELEAELERLDAS--------------------- 683
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 452 SVVLERLRRTLTDYQNKLEDASNEEKACN-ELDSTKQKIDSHTKNIKELQDKLADVNKELSHLHTKCAD-------REAL 523
Cdd:COG4913 684 SDDLAALEEQLEELEAELEELEEELDELKgEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEerfaaalGDAV 763
|
570 580 590
....*....|....*....|....*....|....*....
gi 38348729 524 ISTLKVELQNVLhcwEKEKAQAAQSESELQKLSQAFHKD 562
Cdd:COG4913 764 ERELRENLEERI---DALRARLNRAEEELERAMRAFNRE 799
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
344-566 |
5.52e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.98 E-value: 5.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 344 EREKHNAQESFAKLNLLEKEYFSKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEELVMAKKHQAFLVETCENNVKE 423
Cdd:COG4942 26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 424 LESILDSFTVSGQWTSGIHKDKDKPPSFSVVLERLRRTLTDYQNKLEDASNEEKAcnELDSTKQKIDSHTKNIKELQDKL 503
Cdd:COG4942 106 LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLA--ELAALRAELEAERAELEALLAEL 183
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 38348729 504 ADVNKELSHLHtkcADREALISTLKVELQNVlhcwEKEKAQAAQSESELQKLSQAFHKDAEEK 566
Cdd:COG4942 184 EEERAALEALK---AERQKLLARLEKELAEL----AAELAELQQEAEELEALIARLEAEAAAA 239
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1006-1176 |
5.89e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.54 E-value: 5.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 1006 EMKKELD--KAQGLQMQLNEFKQSKLITHEKFESACEELNNALLREEQAQMLLNEQAQQLQELNYKLELHSSEEADKNQT 1083
Cdd:COG1196 217 ELKEELKelEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 1084 LGEAVKSLSEAKMELRRKDQSLRQLNRHLTQLEQDKRRLEENIHDAESALRMAAKDKECVANHMRAVENTLHKV---RDQ 1160
Cdd:COG1196 297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAeaeLAE 376
|
170
....*....|....*.
gi 38348729 1161 ISLSWSAASRNDFTLQ 1176
Cdd:COG1196 377 AEEELEELAEELLEAL 392
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
99-277 |
7.54e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.96 E-value: 7.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 99 RRAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAFQTSQQKWKEECRRFEHDlEERDNMIQNCNREYDLLMKEKSRLEK 178
Cdd:pfam17380 438 RRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAE-EQRRKILEKELEERKQAMIEEERKRK 516
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 179 TLQEALEKHQREKNEMEShiRETALEEFRLQEEQWEAERrelqfiVQEQDTAVQNMHKKVEKLETEHMdcsdlLRRQTSE 258
Cdd:pfam17380 517 LLEKEMEERQKAIYEEER--RREAEEERRKQQEMEERRR------IQEQMRKATEERSRLEAMERERE-----MMRQIVE 583
|
170
....*....|....*....
gi 38348729 259 lefstqrEERLRKEFEATT 277
Cdd:pfam17380 584 -------SEKARAEYEATT 595
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
169-403 |
8.06e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.14 E-value: 8.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 169 LMKEKSRLEKTLQEALEkHQREKNEMESHIRET-----ALEEFRLQEEQWEAERRELQFIVQEQDTA-VQNMHKKVEKLE 242
Cdd:COG4913 216 YMLEEPDTFEAADALVE-HFDDLERAHEALEDAreqieLLEPIRELAERYAAARERLAELEYLRAALrLWFAQRRLELLE 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 243 TEhmdcsdlLRRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHLESkfnseiIQLRIRDLEGALQVEKASQ 322
Cdd:COG4913 295 AE-------LEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQ------LEREIERLERELEERERRR 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 323 AEAVADLEIIKNEFKEVESAYEREKHNAQESFAKLNLLEKEyfsknkkLNEDIEEQKKVIIDLSKRLQynekscsELQEE 402
Cdd:COG4913 362 ARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEA-------LEEALAEAEAALRDLRRELR-------ELEAE 427
|
.
gi 38348729 403 L 403
Cdd:COG4913 428 I 428
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
65-418 |
8.58e-04 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 43.94 E-value: 8.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 65 SQIAKLRSEVEKGEALRQSLEYDLAVARKEAGLGRRAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAFQTSQQKWK-- 142
Cdd:pfam05483 296 KELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEkn 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 143 ------------------EECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEKTLQEALEKHQR-----EKNEMESHIR 199
Cdd:pfam05483 376 edqlkiitmelqkksselEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQElifllQAREKEIHDL 455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 200 ETALEEFRLQEEQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEH----MDCSDL---LRRQTSELEFSTQREERLRKE 272
Cdd:pfam05483 456 EIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENkeltQEASDMtleLKKHQEDIINCKKQEERMLKQ 535
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 273 FEATTLRVRKLEENIEAERAahlESKFNSEIIQLRIRDLEGALQVEKASQAEAVADLEIIKNEFKEVESAYEREKHNAQE 352
Cdd:pfam05483 536 IENLEEKEMNLRDELESVRE---EFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEE 612
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 38348729 353 SFAKLNLLEKEYFSKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEELVMAKKHQAFLVETCE 418
Cdd:pfam05483 613 LHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVE 678
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
108-795 |
1.35e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.11 E-value: 1.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 108 EAHRIQEKLCAQNSELQAKTNETEKAFQTSQQKWKEECRRFEHDLEERDNMIQNCNREYDLLMKeksrLEKTLQeALEKH 187
Cdd:TIGR00606 203 QEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMK----LDNEIK-ALKSR 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 188 QREKNEMESHIRETALEEFRLQEEQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEhmdcSDLLRRQTSELEFSTQR-- 265
Cdd:TIGR00606 278 KKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKE----RRLLNQEKTELLVEQGRlq 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 266 ------------------EERLRKEFE--------------ATTLRVRKLEEniEAERAAHLESKFNSEI---------I 304
Cdd:TIGR00606 354 lqadrhqehirardsliqSLATRLELDgfergpfserqiknFHTLVIERQED--EAKTAAQLCADLQSKErlkqeqadeI 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 305 QLRIRDLEGALQVEKASQAEAVADLEIIKNEFKEVESAYEREKHNAQE---SFAKLNLLEKEYFSKNKKLNEDIEEQKKV 381
Cdd:TIGR00606 432 RDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQElrkAERELSKAEKNSLTETLKKEVKSLQNEKA 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 382 IIDLSKRL------QYNEKSCSELQEELVMAKKHQAF--LVETCENNVKELESILDSFTVSGQWTSGIH-KDKDKPPS-- 450
Cdd:TIGR00606 512 DLDRKLRKldqemeQLNHHTTTRTQMEMLTKDKMDKDeqIRKIKSRHSDELTSLLGYFPNKKQLEDWLHsKSKEINQTrd 591
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 451 ------------------FSVVLERLRRTLTDYQNKLEDASNEEKACNELDSTKQKIDSHTKNIKELQDKLADVNKELSH 512
Cdd:TIGR00606 592 rlaklnkelasleqnknhINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQ 671
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 513 LHTK---CADREALISTLKVELQNVLHCWEKEKAQAAQSESELQKLSQAFHKDAEEKLTFLHTLYQHLVAGCVLIKQPEG 589
Cdd:TIGR00606 672 LTDEnqsCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRN 751
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 590 MLDKFSWSelCAVLQENVDALIADLNRANEKIRHLEyICKNKSDTMRELQQTQEDTFTKVAEQIKAQESCwhrqkkELEL 669
Cdd:TIGR00606 752 KLQKVNRD--IQRLKNDIEEQETLLGTIMPEEESAK-VCLTDVTIMERFQMELKDVERKIAQQAAKLQGS------DLDR 822
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 670 QYSELFLEVQKRAQKFQEIAEKNMEKLNHIEKSHEQLvlenSHFKKLLSQTQREQMSL---LAACALMAGALYPLYSRSC 746
Cdd:TIGR00606 823 TVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQI----QHLKSKTNELKSEKLQIgtnLQRRQQFEEQLVELSTEVQ 898
|
730 740 750 760
....*....|....*....|....*....|....*....|....*....
gi 38348729 747 ALSTQRDFLQEQVNTFELFKLEIRTLAQALSTVEEKKQEEAKMKKKTFK 795
Cdd:TIGR00606 899 SLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIK 947
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
982-1141 |
1.46e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 43.00 E-value: 1.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 982 RLHAAEVERRSLRLEVTEFKRSVNEMKKELDKAQ----GLQMQLNEFKQSKLITHEKFESACEELNNALLREEQAQMLLN 1057
Cdd:COG1196 226 EAELLLLKLRELEAELEELEAELEELEAELEELEaelaELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 1058 EQAQQLQELNYKLELHSSEEADKNQTLGEAVKSLSEAKMELRRKDQSLRQLNRHLTQLEQDKRRLEENIHDAESALRMAA 1137
Cdd:COG1196 306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385
|
....
gi 38348729 1138 KDKE 1141
Cdd:COG1196 386 EELL 389
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
976-1141 |
1.93e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 1.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 976 ILGFT--QRLHAAEVERRSLRLEVTEFKRSVNEMKKELDKAQGLQMQLnefkqsklithekfeSACEELNNALLREEQAQ 1053
Cdd:COG4913 603 VLGFDnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAL---------------QRLAEYSWDEIDVASAE 667
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 1054 MLLNEQAQQLQELnyklelhsseEADkNQTLGEAVKSLSEAKMELRRKDQSLRQLNRHLTQLEQDKRRLEENIHDAESAL 1133
Cdd:COG4913 668 REIAELEAELERL----------DAS-SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRL 736
|
....*...
gi 38348729 1134 RMAAKDKE 1141
Cdd:COG4913 737 EAAEDLAR 744
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
313-558 |
1.94e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.12 E-value: 1.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 313 GALQVEKASQAEAVADLEIIKNEFKEVESAYEREKHNAQESFAKLNLLEKEYfsknKKLNEDIEEQKKVIIDLSKRLQYN 392
Cdd:COG3883 2 LALALAAPTPAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEY----NELQAELEALQAEIDKLQAEIAEA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 393 EKSCSELQEELvmakKHQAFLVETCENNVKELESILDSftvsgqwtsgihkdkdkpPSFSVVLERL--RRTLTDYQNKLE 470
Cdd:COG3883 78 EAEIEERREEL----GERARALYRSGGSVSYLDVLLGS------------------ESFSDFLDRLsaLSKIADADADLL 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 471 DASNEEKAcnELDSTKQKIDshtKNIKELQDKLADVNKELSHLHTKCADREALISTLKVELQNVLHCWEKEKAQAAQSES 550
Cdd:COG3883 136 EELKADKA--ELEAKKAELE---AKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEA 210
|
....*...
gi 38348729 551 ELQKLSQA 558
Cdd:COG3883 211 AAAAAAAA 218
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
58-307 |
2.10e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.06 E-value: 2.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 58 AELASYESQIAKLRSEVEKGEALRQSLEYDLAvarkeaglgrrAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAFQTS 137
Cdd:COG4942 27 AELEQLQQEIAELEKELAALKKEEKALLKQLA-----------ALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 138 QQKWKEEcrrfEHDLEERDNMIQNCNREYDLLMKEKSRLEKTLQEALEKHQREKNEmeshiRETALEEFRLQEEQWEAER 217
Cdd:COG4942 96 RAELEAQ----KEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPA-----RREQAEELRADLAELAALR 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 218 RELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHLES 297
Cdd:COG4942 167 AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
|
250
....*....|
gi 38348729 298 KFNSEIIQLR 307
Cdd:COG4942 247 GFAALKGKLP 256
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
967-1133 |
2.30e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 42.59 E-value: 2.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 967 KSTASLQKQILGFTQRLhaaeverRSLRLEVTEFKRSVNEMKKE----LDKAQgLQMQLNEfkqskliTHEKFESACEEL 1042
Cdd:PRK11281 80 EETEQLKQQLAQAPAKL-------RQAQAELEALKDDNDEETREtlstLSLRQ-LESRLAQ-------TLDQLQNAQNDL 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 1043 N--NALL-----REEQAQMLLNEQAQQLQELNykLELHSSEEADKN-----QTLGEAVKSLSEAKMELRRKD-------Q 1103
Cdd:PRK11281 145 AeyNSQLvslqtQPERAQAALYANSQRLQQIR--NLLKGGKVGGKAlrpsqRVLLQAEQALLNAQNDLQRKSlegntqlQ 222
|
170 180 190
....*....|....*....|....*....|
gi 38348729 1104 SLRQLNRHLTQLEQDkrRLEENIHDAESAL 1133
Cdd:PRK11281 223 DLLQKQRDYLTARIQ--RLEHQLQLLQEAI 250
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
970-1126 |
3.31e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.68 E-value: 3.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 970 ASLQKQILGFTQRLHAAEVERRSLRLEVTEFKRSVNEMKKELDKAQGLQMQLNEFKQSKLITHEkfesaceelnnallrE 1049
Cdd:COG1579 34 AELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEALQKE---------------I 98
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 38348729 1050 EQAQMLLNEQAQQLQELNYKLELHSSEEADKNQTLGEAVKSLSEAKMELrrkDQSLRQLNRHLTQLEQDKRRLEENI 1126
Cdd:COG1579 99 ESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAEL---DEELAELEAELEELEAEREELAAKI 172
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
38-403 |
3.56e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.68 E-value: 3.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 38 LRKKLHWAKKEKLEITTKHNaELASYESQIAKLRSEVEKGEALRQSLEYdlAVARKEAGLGRRAAEERLAEAHRIQEKLC 117
Cdd:COG4717 76 LEEELKEAEEKEEEYAELQE-ELEELEEELEELEAELEELREELEKLEK--LLQLLPLYQELEALEAELAELPERLEELE 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 118 AQNSELQAKTNETEKAFQTSQQKWKEECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLE---KTLQEALEKHQREKNEM 194
Cdd:COG4717 153 ERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEeelEEAQEELEELEEELEQL 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 195 ESHIRETALEEfRLQEEQWEAERRELQFIVQEQDTAVQNMHKKVEK----------LETEHMDCSDLLRRQTSELEFSTQ 264
Cdd:COG4717 233 ENELEAAALEE-RLKEARLLLLIAAALLALLGLGGSLLSLILTIAGvlflvlgllaLLFLLLAREKASLGKEAEELQALP 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 265 REERLRKEFEATTLRVRKLEENIEAERAAHLESKFnSEIIQL--RIRDLEGALQVEkASQAEAVADLEIIKNEFKE---- 338
Cdd:COG4717 312 ALEELEEEELEELLAALGLPPDLSPEELLELLDRI-EELQELlrEAEELEEELQLE-ELEQEIAALLAEAGVEDEEelra 389
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 38348729 339 -VESAYEREKHNAQESFAKLNLLEKEYFSKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEEL 403
Cdd:COG4717 390 aLEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREEL 455
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
986-1162 |
3.66e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.98 E-value: 3.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 986 AEVERRSLRLEvtEFKRSVNEMKKELDKAQGLqmqLNEFKQSKLITHEKFESACEELNNALLREEQAQMLLNEQAQQLQE 1065
Cdd:TIGR02169 674 AELQRLRERLE--GLKRELSSLQSELRRIENR---LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSS 748
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 1066 LNYKLELHSSEEADKNQTLGEAVKSLSEAKMEL-----RRKDQSLRQLNRHLTQLEQDKRRLEENIHDAESALRMAAKDK 1140
Cdd:TIGR02169 749 LEQEIENVKSELKELEARIEELEEDLHKLEEALndleaRLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK 828
|
170 180
....*....|....*....|..
gi 38348729 1141 ECVANHMRAVENTLHKVRDQIS 1162
Cdd:TIGR02169 829 EYLEKEIQELQEQRIDLKEQIK 850
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
965-1138 |
3.74e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.29 E-value: 3.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 965 ITKSTASLQKQILGFTQRLHAAEVERRSLRLEVTEFKRSVNEMKKELDKAQG-LQMQLNEFKQSKLITHEKFESACEELN 1043
Cdd:COG4942 53 LLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEeLAELLRALYRLGRQPPLALLLSPEDFL 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 1044 ---------NALLREEQAQML-LNEQAQQLQELNYKLELHSSEEADKNQTLGEAVKSLSEAKME----LRRKDQSLRQLN 1109
Cdd:COG4942 133 davrrlqylKYLAPARREQAEeLRADLAELAALRAELEAERAELEALLAELEEERAALEALKAErqklLARLEKELAELA 212
|
170 180
....*....|....*....|....*....
gi 38348729 1110 RHLTQLEQDKRRLEENIHDAESALRMAAK 1138
Cdd:COG4942 213 AELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
45-585 |
4.85e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 41.49 E-value: 4.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 45 AKKEKLEITTKHNAELASYESQIAKLRSEVEKGEALRQSLEYDLAVARKEAGLGRRAAEE--------------RLAEAH 110
Cdd:TIGR00618 383 TLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELcaaaitctaqceklEKIHLQ 462
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 111 RIQEKLCAQNSELQAKTNETEKAFQTSQ--QKWKEECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEKTLQEALEKHQ 188
Cdd:TIGR00618 463 ESAQSLKEREQQLQTKEQIHLQETRKKAvvLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLET 542
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 189 REKNemESHIRETALEEFRLQEEQWEAERRELQFIVQeQDTAVQNMHKKVEKLETEHMDCSDLLRRQTSELEFSTQREER 268
Cdd:TIGR00618 543 SEED--VYHQLTSERKQRASLKEQMQEIQQSFSILTQ-CDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLR 619
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 269 lRKEFEATTLRVRKLEENIEaERAAHLESKFNSEIIQLRIRDLEGALQVEKASQAEAvadLEIIKNEFKEVESAYEREKH 348
Cdd:TIGR00618 620 -KLQPEQDLQDVRLHLQQCS-QELALKLTALHALQLTLTQERVREHALSIRVLPKEL---LASRQLALQKMQSEKEQLTY 694
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 349 NaQESFAKLNLLEKEYFSKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEELvMAKKHQAFLVETCENNVKELESIL 428
Cdd:TIGR00618 695 W-KEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKEL-MHQARTVLKARTEAHFNNNEEVTA 772
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 429 DSFTvsgqwtsgihkdkdkppsfsvvLERLRRTLTDYQNKLEDASNEEKACNELDSTKQKIDSHTKNIKELQDKLadVNK 508
Cdd:TIGR00618 773 ALQT----------------------GAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCET--LVQ 828
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 38348729 509 ELSHLHTKCADREALISTLKVELQNVLHCwEKEKAQAAQSESELQKLSQAFHKDAEEKLTFLHTLYQHLVAGCVLIK 585
Cdd:TIGR00618 829 EEEQFLSRLEEKSATLGEITHQLLKYEEC-SKQLAQLTQEQAKIIQLSDKLNGINQIKIQFDGDALIKFLHEITLYA 904
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
16-515 |
6.10e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 41.04 E-value: 6.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 16 KIASLDVKQILKNETELDITDNLRKKLHWAKKE---KLEITTKHNAELASYESQIAKLRSEVEKGEALRQ---SLEYDLA 89
Cdd:PRK01156 211 KSHSITLKEIERLSIEYNNAMDDYNNLKSALNElssLEDMKNRYESEIKTAESDLSMELEKNNYYKELEErhmKIINDPV 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 90 VARKEAGLGRRAAEERLAEAHRIQEKLCAQ----------NSELQAKTNETEKafqtsQQKWKEECRRFEHDLEERDNMI 159
Cdd:PRK01156 291 YKNRNYINDYFKYKNDIENKKQILSNIDAEinkyhaiikkLSVLQKDYNDYIK-----KKSRYDDLNNQILELEGYEMDY 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 160 QNCNREYDLLMKEksrlektlqeaLEKHQREKNEMESHIRETALEEFrLQEEQWEAERRELQFIVQEQDTAVQNMHKKVE 239
Cdd:PRK01156 366 NSYLKSIESLKKK-----------IEEYSKNIERMSAFISEILKIQE-IDPDAIKKELNEINVKLQDISSKVSSLNQRIR 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 240 KLETEHMDcsdlLRRQTSELE-----------FSTQREERLRKEFEATTLR----VRKLEENIEA--ERAAHLEsKFNSE 302
Cdd:PRK01156 434 ALRENLDE----LSRNMEMLNgqsvcpvcgttLGEEKSNHIINHYNEKKSRleekIREIEIEVKDidEKIVDLK-KRKEY 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 303 IIQLRIRDLEGALQVEKASQAEaVADLEIIKNEFKEVESAYEREKH--------------------NAQESFAKLNLLEK 362
Cdd:PRK01156 509 LESEEINKSINEYNKIESARAD-LEDIKIKINELKDKHDKYEEIKNrykslkledldskrtswlnaLAVISLIDIETNRS 587
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 363 EYFSKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEElVMAKKHQAFLVETCENNVKELESILDSFtvsgqwTSGIH 442
Cdd:PRK01156 588 RSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENE-ANNLNNKYNEIQENKILIEKLRGKIDNY------KKQIA 660
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 38348729 443 KDKDKPPSFSVVLERLRRTLTDYqNKLEDASNEEKAcnELDSTKQKIDSHTKNIKELQDKLADVNKELSHLHT 515
Cdd:PRK01156 661 EIDSIIPDLKEITSRINDIEDNL-KKSRKALDDAKA--NRARLESTIEILRTRINELSDRINDINETLESMKK 730
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
67-373 |
6.11e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 40.98 E-value: 6.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 67 IAKLRSEVEKGEALRQSLEYDLAvarKEAGLGRRAAEERLAEAHRIQEKlcaqnselQAKTNETEKAFQTSQQKWKEECR 146
Cdd:pfam12128 236 IMKIRPEFTKLQQEFNTLESAEL---RLSHLHFGYKSDETLIASRQEER--------QETSAELNQLLRTLDDQWKEKRD 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 147 RFEHDLEERDNMIQNCNREYDLLMKEKSRLEKTLQEALEKHQRE----KNEMESHIRETALEEFRLQEEQWEAERRElQF 222
Cdd:pfam12128 305 ELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQlpswQSELENLEERLKALTGKHQDVTAKYNRRR-SK 383
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 223 IVQEQDTAVQNMHKKVEKL----ETEHMDCSDLLRRQTSElefstqreerLRKEFEATTLRVRKLEENIEaERAAHL--- 295
Cdd:pfam12128 384 IKEQNNRDIAGIKDKLAKIrearDRQLAVAEDDLQALESE----------LREQLEAGKLEFNEEEYRLK-SRLGELklr 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 296 --------ESKFNSEIIQLRIRDLEGALQVEKASQAEAVADLEIIKNEFKEVESAYEREKHNAQESFAKLNLLEKEYFSK 367
Cdd:pfam12128 453 lnqatatpELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQ 532
|
....*.
gi 38348729 368 NKKLNE 373
Cdd:pfam12128 533 AGTLLH 538
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
336-723 |
8.09e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 40.82 E-value: 8.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 336 FKEVESAYEREKhnAQESFAKLNLLEKEYFSknkkLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEELVMAKKHQAFLVE 415
Cdd:TIGR02169 664 GGILFSRSEPAE--LQRLRERLEGLKRELSS----LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKE 737
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 416 TCENNVKELESILDsftvsgqwtsGIHKDKDKPPSFSVVLERLRRTLTDYQNKLEDASNEEkACNELDSTKQKIDSHTKN 495
Cdd:TIGR02169 738 RLEELEEDLSSLEQ----------EIENVKSELKELEARIEELEEDLHKLEEALNDLEARL-SHSRIPEIQAELSKLEEE 806
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 496 IKELQDKLADVNKELSHLHTkcadREALISTLKVELQNVLHCWEKEKAQAAQSESELQKLSQAFHKDAEEKLTFLHTLYQ 575
Cdd:TIGR02169 807 VSRIEARLREIEQKLNRLTL----EKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLES 882
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 576 HLVAgcvlikqpegmldkfswselcavLQENVDALIADLNRANEKIRHLEYicknKSDTMRELQQTQEDTFTKVAEQIKA 655
Cdd:TIGR02169 883 RLGD-----------------------LKKERDELEAQLRELERKIEELEA----QIEKKRKRLSELKAKLEALEEELSE 935
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 656 QESCWHRQKK--ELELQYSELFLEVQKRAQKFQEIAEKNM----------EKLNHIEKSHEQLVLENSHFKKLLSQTQRE 723
Cdd:TIGR02169 936 IEDPKGEDEEipEEELSLEDVQAELQRVEEEIRALEPVNMlaiqeyeevlKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
97-294 |
8.12e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.53 E-value: 8.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 97 LGRRAAEERLAEAHRIQEKLcAQNSELQAKTNETEKAFQtSQQKWKEECRRFEHDLEERDNMIQncnreydllmkeksRL 176
Cdd:PRK12704 24 VRKKIAEAKIKEAEEEAKRI-LEEAKKEAEAIKKEALLE-AKEEIHKLRNEFEKELRERRNELQ--------------KL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 177 EKTLQealekhQREKNeMESHIRETALEEFRLQEEQWEAERRELQfivqeqdtaVQNMHKKVEKLETEHMDcsdllrrqt 256
Cdd:PRK12704 88 EKRLL------QKEEN-LDRKLELLEKREEELEKKEKELEQKQQE---------LEKKEEELEELIEEQLQ--------- 142
|
170 180 190
....*....|....*....|....*....|....*...
gi 38348729 257 sELEfstqREERLRKEfEATTLRVRKLEENIEAERAAH 294
Cdd:PRK12704 143 -ELE----RISGLTAE-EAKEILLEKVEEEARHEAAVL 174
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
51-289 |
8.36e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 40.54 E-value: 8.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 51 EITTKHNAELASYESQIAKLRSEVEKGEALRQSLEYDlavaRKEAGLGRRAAEERLAEAHRIQEKLCAQNSELQAKTNET 130
Cdd:pfam01576 349 EMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESE----NAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSES 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 131 EKAfqtsQQKWKEECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEKTL---QEALEKHQREKNEMESHIRetaleefr 207
Cdd:pfam01576 425 ERQ----RAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLqdtQELLQEETRQKLNLSTRLR-------- 492
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 208 lqeeQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQTSELEFSTQREERLRKEFEATTLRvrkLEENI 287
Cdd:pfam01576 493 ----QLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQ---LEEKA 565
|
..
gi 38348729 288 EA 289
Cdd:pfam01576 566 AA 567
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
346-565 |
8.50e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 40.38 E-value: 8.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 346 EKHNAQEsfaKLNLLEKEYFSKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEELVmakkhqaflvetceNNVKELE 425
Cdd:PHA02562 189 KIDHIQQ---QIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELL--------------NLVMDIE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 426 SILDSFtvsGQWTSGIHKDKDKPPSFSVVLERLR---------RTLTDYQNKLEDASNEEKACN-ELDstkqKIDSHTKN 495
Cdd:PHA02562 252 DPSAAL---NKLNTAAAKIKSKIEQFQKVIKMYEkggvcptctQQISEGPDRITKIKDKLKELQhSLE----KLDTAIDE 324
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 496 IKELQDKLADVNKELSHLHTKcadrealISTLKVELQNvlhcwekEKAQAAQSESELQKLSQAFHKDAEE 565
Cdd:PHA02562 325 LEEIMDEFNEQSKKLLELKNK-------ISTNKQSLIT-------LVDKAKKVKAAIEELQAEFVDNAEE 380
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
121-341 |
8.81e-03 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 40.49 E-value: 8.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 121 SELQAKTNETEKAFQTSQQKWKEECRRFEHdLEERDNMIQNCNREydllMKEKSRLEKTLQEALEKHQREKNEMESHIRE 200
Cdd:pfam05557 30 IELEKKASALKRQLDRESDRNQELQKRIRL-LEKREAEAEEALRE----QAELNRLKKKYLEALNKKLNEKESQLADARE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 201 TALE-EFRLQEEQWEAERRELQFIVQ------------EQDTAVQNMHKKVEKLETEHMDCSDlLRRQTSELEFSTQREE 267
Cdd:pfam05557 105 VISClKNELSELRRQIQRAELELQSTnseleelqerldLLKAKASEAEQLRQNLEKQQSSLAE-AEQRIKELEFEIQSQE 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38348729 268 R---LRKEFEATTLRVRKLEENIEA--ERAAHL-ESKFNSEIIQLRIRDLEGALQVEKASQAEAVA---DLEIIKNEFKE 338
Cdd:pfam05557 184 QdseIVKNSKSELARIPELEKELERlrEHNKHLnENIENKLLLKEEVEDLKRKLEREEKYREEAATlelEKEKLEQELQS 263
|
...
gi 38348729 339 VES 341
Cdd:pfam05557 264 WVK 266
|
|
| |
