|
Name |
Accession |
Description |
Interval |
E-value |
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
523-1297 |
2.14e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 78.56 E-value: 2.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 523 KLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDsgmaesRQMKRAEPHQLRQEdSD 602
Cdd:TIGR02168 247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQ------KQILRERLANLERQ-LE 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 603 AVWNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELN--RCMAEKREEQLFRQHEDAEVKKSTPEKNEKAIS 680
Cdd:TIGR02168 320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEaeLEELESRLEELEEQLETLRSKVAQLELQIASLN 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 681 EEtlqkVIELENRLKSFEKNSRKLKEESKRLKKEndFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITAL 760
Cdd:TIGR02168 400 NE----IERLEARLERLEDRRERLQQEIEELLKK--LEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 761 ETEVTTLRRQVTEAKALRGKDEEVvcpEERAHRPTDKAKSEMATTDVRARRCDCKTATTKV--KFKAAKRK-CSVGRHHT 837
Cdd:TIGR02168 474 EQALDAAERELAQLQARLDSLERL---QENLEGFSEGVKALLKNQSGLSGILGVLSELISVdeGYEAAIEAaLGGRLQAV 550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 838 VLNHSIKVMSHVENLSKdgwedvsegSDSETQTFQNLGTI----IVETSQNISPIEDGRNQKEIDQTEGSCAQQRAMQ-- 911
Cdd:TIGR02168 551 VVENLNAAKKAIAFLKQ---------NELGRVTFLPLDSIkgteIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyl 621
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 912 ---TYSCEDIKAPQSIShNKNTKKMTFQKKSGSLQKSLHSALPARVNREkcknlpaqkssSSTISLRERIVSLQQQNSLL 988
Cdd:TIGR02168 622 lggVLVVDDLDNALELA-KKLRPGYRIVTLDGDLVRPGGVITGGSAKTN-----------SSILERRREIEELEEKIEEL 689
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 989 QNARRAAEASAKEYKEANEKLLHQQQVSDHRFQTSRQTIKKLTLDLAELRKEKEDLLKKVESSSDIMSLAEEVSRIMAPQ 1068
Cdd:TIGR02168 690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER 769
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1069 IKVTTLGPSRSMDlEMKQLQCKLKNATNELTKQSSNVKSLRMELLAKDDHIKEMHERTSRMERDITMKRHLIEDLKFRQK 1148
Cdd:TIGR02168 770 LEEAEEELAEAEA-EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1149 VNSESNESFNEMLETLEKKVKSLTEEcsnkkvsvdslkqrLNVAVKEKSQYEQMYQKTKEELEKKDlkmsvliSKLNDTE 1228
Cdd:TIGR02168 849 ELSEDIESLAAEIEELEELIEELESE--------------LEALLNERASLEEALALLRSELEELS-------EELRELE 907
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 87299624 1229 TAMAQIETAASEqLQGLALQSEQVLEGAQKKLLSANEKI-EEFTV---FVKALVNELQSDVHGTRHQIRELKK 1297
Cdd:TIGR02168 908 SKRSELRRELEE-LREKLAQLELRLEGLEVRIDNLQERLsEEYSLtleEAEALENKIEDDEEEARRRLKRLEN 979
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
131-783 |
2.29e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.48 E-value: 2.29e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 131 RRLQATNPDLTQTVSLVVEREKQKSEAKDRkvleiLQVKDSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCD 210
Cdd:TIGR02168 260 AELQELEEKLEELRLEVSELEEEIEELQKE-----LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDE 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 211 LQKKFKDKSQEVKDAKECVQSKEEQN----------RLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDT 280
Cdd:TIGR02168 335 LAEELAELEEKLEELKEELESLEAELeeleaeleelESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLED 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 281 RVKVLEENLIEAKKEIESAQTKynVVSQQLNNKQAELLQKDMDITLIRKELQELQNVYKQNSAHTAQQADLIQQLQALNM 360
Cdd:TIGR02168 415 RRERLQQEIEELLKKLEEAELK--ELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 361 DTQKVLRNQEDVHT--AESMSYQKLYNELHMCF--------ETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQ 430
Cdd:TIGR02168 493 SLERLQENLEGFSEgvKALLKNQSGLSGILGVLselisvdeGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGR 572
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 431 GTAPSLSPHDSDSSHSGKAPLSTLETLMISQKSEIEYLQKKLKVANEKLMANRSCDQDFSEkGTEGKHKEPP-------- 502
Cdd:TIGR02168 573 VTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDN-ALELAKKLRPgyrivtld 651
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 503 ---VKRSRSLSPKSSFMGSEEL---RKLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLqmlhtnyravkEQLKQW 576
Cdd:TIGR02168 652 gdlVRPGGVITGGSAKTNSSILerrREIEELEEKIEELEEKIAELEKALAELRKELEELEEEL-----------EQLRKE 720
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 577 EEDSGMAESRQMKRAEPHQLRQEDSDAVWNELayfKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEKREE 656
Cdd:TIGR02168 721 LEELSRQISALRKDLARLEAEVEQLEERIAQL---SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE 797
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 657 qlFRQHEDAEVKKSTPEKNEKAISEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKEL 736
Cdd:TIGR02168 798 --LKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL 875
|
650 660 670 680
....*....|....*....|....*....|....*....|....*..
gi 87299624 737 EQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEAKALRGKDEE 783
Cdd:TIGR02168 876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE 922
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
154-741 |
5.71e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 60.72 E-value: 5.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 154 KSEAKDRKVLEILqvkdSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKDAKECVQSKE 233
Cdd:COG1196 219 KEELKELEAELLL----LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 234 EQNRLVIKNLEEENERLRtrctDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQLNNK 313
Cdd:COG1196 295 AELARLEQDIARLEERRR----ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 314 QAELLQKDMDITLIRKELQELQN---VYKQNSAHTAQQADLIQQLQALNMDTQKVLRNQEDVHTAESMSYQKLYNELHMC 390
Cdd:COG1196 371 EAELAEAEEELEELAEELLEALRaaaELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 391 FETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESqgtAPSLSPHDSDSSHSGKAPLSTLETLMISQKSEI----- 465
Cdd:COG1196 451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA---AARLLLLLEAEADYEGFLEGVKAALLLAGLRGLagava 527
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 466 ------EYLQKKLKVANEKLMANRSCDQDFSEKGTEGKHKE-----------PPVKRSRSLSPKSSFMGSEELRKLKKAE 528
Cdd:COG1196 528 vligveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAakagratflplDKIRARAALAAALARGAIGAAVDLVASD 607
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 529 RKIENLEKTLQLKS-QENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRAEPHQLRQEDSDAVWNE 607
Cdd:COG1196 608 LREADARYYVLGDTlLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAER 687
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 608 LAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTPEKNEKAI-SEETLQK 686
Cdd:COG1196 688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPpDLEELER 767
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*..
gi 87299624 687 VIE-LENRLKSFEK-NSRKLkEESKRLKKENDFLKSHLkhyqEDSEAREKELEQLLR 741
Cdd:COG1196 768 ELErLEREIEALGPvNLLAI-EEYEELEERYDFLSEQR----EDLEEARETLEEAIE 819
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
1147-1269 |
2.69e-05 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 48.67 E-value: 2.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1147 QKVNSESNESFNEM---LETLEKKVKSLTEECSNKKVSVDSLKQRLNvavKEKSQYEQMYQKTKEELEKKdLKMSVLISK 1223
Cdd:PRK00409 508 KKLIGEDKEKLNELiasLEELERELEQKAEEAEALLKEAEKLKEELE---EKKEKLQEEEDKLLEEAEKE-AQQAIKEAK 583
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 87299624 1224 lndtETAMAQIETAASEQLQGLALQSEQVLEGAQKKLLSANEKIEE 1269
Cdd:PRK00409 584 ----KEADEIIKELRQLQKGGYASVKAHELIEARKRLNKANEKKEK 625
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
153-358 |
4.07e-05 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 48.37 E-value: 4.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 153 QKSEAKDRKVLEilQVKDSKIQELEQTESVLKQelhdlvklKTLVDEENAFLRKELCDLQKKFKdksqevkdakecvQSK 232
Cdd:PRK11281 44 QLDALNKQKLLE--AEDKLVQQDLEQTLALLDK--------IDRQKEETEQLKQQLAQAPAKLR-------------QAQ 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 233 EEQNRLVIKNLEEENERLRTRC-TDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQLN 311
Cdd:PRK11281 101 AELEALKDDNDEETRETLSTLSlRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLK 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 87299624 312 NK---------------QAELLQKDMDITLIRKELQ---ELQNVY-KQNSAHTAQQADLIQQLQAL 358
Cdd:PRK11281 181 GGkvggkalrpsqrvllQAEQALLNAQNDLQRKSLEgntQLQDLLqKQRDYLTARIQRLEHQLQLL 246
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
385-805 |
2.23e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 45.88 E-value: 2.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 385 NELHmcfettKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDSDSSHSGKAPLSTLETLMISQKSE 464
Cdd:pfam15921 98 NELH------EKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQ 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 465 IEYLQKKLKVANEKLMANRSCDQDFSEKGTEGKHKEPPVK--RSRSLSPKSSFMGSE---ELRKLKKAERKIENLEKTLQ 539
Cdd:pfam15921 172 IEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMStmHFRSLGSAISKILREldtEISYLKGRIFPVEDQLEALK 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 540 LKSQENDE-LRDAHEKRKERLQMLHTnyravkeqlkqwEEDSGMAESRQMKRAEPHQLRQEdsdavwNELAYFKRENQEL 618
Cdd:pfam15921 252 SESQNKIElLLQQHQDRIEQLISEHE------------VEITGLTEKASSARSQANSIQSQ------LEIIQEQARNQNS 313
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 619 MVQKmtlqdELDELKMHMSIDKTTIQELNRcMAEKREEQLFRQHEDAEVKKSTPEKNEKAISEETLQKVIELENRLKSFE 698
Cdd:pfam15921 314 MYMR-----QLSDLESTVSQLRSELREAKR-MYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLH 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 699 KNSRKL---KEESKRL---KKENDFLKSHLKHYQEDSEAREKELEQLLRVSKD-----VEHDKSELQTKITALEtEVTTL 767
Cdd:pfam15921 388 KREKELsleKEQNKRLwdrDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSecqgqMERQMAAIQGKNESLE-KVSSL 466
|
410 420 430
....*....|....*....|....*....|....*...
gi 87299624 768 RRQVTEAKALRGKDEEVVCPEERAHRPTDKAKSEMATT 805
Cdd:pfam15921 467 TAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTAS 504
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
148-775 |
5.75e-04 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 44.33 E-value: 5.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 148 VEREKQKSEAKDRKVLEILQVKDSKIQELE-QTESVLKQELHDLVKLKTLVDEENAflRKELCDLQKKFKDKSQEVKDAK 226
Cdd:pfam05483 97 IEAELKQKENKLQENRKIIEAQRKAIQELQfENEKVSLKLEEEIQENKDLIKENNA--TRHLCNLLKETCARSAEKTKKY 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 227 EcvqSKEEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSvdtRVKVLEEnliEAKKEIESAQTKYNVV 306
Cdd:pfam05483 175 E---YEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEMHFKLKEDHE---KIQHLEE---EYKKEINDKEKQVSLL 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 307 SQQLNNKQaellQKDMDITLIRKElqelqnvykqnSAHTAQQADLIQQLQALNMdtqKVLRNQEDVHTAEsmsyqklYNE 386
Cdd:pfam05483 246 LIQITEKE----NKMKDLTFLLEE-----------SRDKANQLEEKTKLQDENL---KELIEKKDHLTKE-------LED 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 387 LHMCFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDsdsshsgKAPLSTLETLMISQKSEIE 466
Cdd:pfam05483 301 IKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEF-------EATTCSLEELLRTEQQRLE 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 467 YLQKKLKVANEKLMaNRSCDQDFSEKGTEGKHKEppvkrsrsLSPKSSFMGSEElrKLKKAERKIENLEKTLQLKSQEND 546
Cdd:pfam05483 374 KNEDQLKIITMELQ-KKSSELEEMTKFKNNKEVE--------LEELKKILAEDE--KLLDEKKQFEKIAEELKGKEQELI 442
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 547 ELRDAHEKRKERLQMLHTNYRAVKEQ-LKQWEEDSGMAESRQMKRAEphqlrqedsdavwnelayFKRENQELMVQKMTL 625
Cdd:pfam05483 443 FLLQAREKEIHDLEIQLTAIKTSEEHyLKEVEDLKTELEKEKLKNIE------------------LTAHCDKLLLENKEL 504
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 626 QDELDELKMHMsidKTTIQELNRCmaEKREEQLFRQHEDAEVKKSTPEKNEKAISEETLQKVIELENRLKSFEKNSRKLK 705
Cdd:pfam05483 505 TQEASDMTLEL---KKHQEDIINC--KKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIE 579
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 706 EESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEAK 775
Cdd:pfam05483 580 YEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAK 649
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
519-784 |
3.07e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 42.23 E-value: 3.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 519 EELR-KLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEdsgmaesrqmkraephqlr 597
Cdd:COG1196 270 EELRlELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE------------------- 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 598 qedsdavwnELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTpeknek 677
Cdd:COG1196 331 ---------ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA------ 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 678 aisEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKI 757
Cdd:COG1196 396 ---AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
|
250 260
....*....|....*....|....*..
gi 87299624 758 TALETEVTTLRRQVTEAKALRGKDEEV 784
Cdd:COG1196 473 ALLEAALAELLEELAEAAARLLLLLEA 499
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
523-1297 |
2.14e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 78.56 E-value: 2.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 523 KLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDsgmaesRQMKRAEPHQLRQEdSD 602
Cdd:TIGR02168 247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQ------KQILRERLANLERQ-LE 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 603 AVWNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELN--RCMAEKREEQLFRQHEDAEVKKSTPEKNEKAIS 680
Cdd:TIGR02168 320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEaeLEELESRLEELEEQLETLRSKVAQLELQIASLN 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 681 EEtlqkVIELENRLKSFEKNSRKLKEESKRLKKEndFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITAL 760
Cdd:TIGR02168 400 NE----IERLEARLERLEDRRERLQQEIEELLKK--LEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 761 ETEVTTLRRQVTEAKALRGKDEEVvcpEERAHRPTDKAKSEMATTDVRARRCDCKTATTKV--KFKAAKRK-CSVGRHHT 837
Cdd:TIGR02168 474 EQALDAAERELAQLQARLDSLERL---QENLEGFSEGVKALLKNQSGLSGILGVLSELISVdeGYEAAIEAaLGGRLQAV 550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 838 VLNHSIKVMSHVENLSKdgwedvsegSDSETQTFQNLGTI----IVETSQNISPIEDGRNQKEIDQTEGSCAQQRAMQ-- 911
Cdd:TIGR02168 551 VVENLNAAKKAIAFLKQ---------NELGRVTFLPLDSIkgteIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyl 621
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 912 ---TYSCEDIKAPQSIShNKNTKKMTFQKKSGSLQKSLHSALPARVNREkcknlpaqkssSSTISLRERIVSLQQQNSLL 988
Cdd:TIGR02168 622 lggVLVVDDLDNALELA-KKLRPGYRIVTLDGDLVRPGGVITGGSAKTN-----------SSILERRREIEELEEKIEEL 689
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 989 QNARRAAEASAKEYKEANEKLLHQQQVSDHRFQTSRQTIKKLTLDLAELRKEKEDLLKKVESSSDIMSLAEEVSRIMAPQ 1068
Cdd:TIGR02168 690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER 769
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1069 IKVTTLGPSRSMDlEMKQLQCKLKNATNELTKQSSNVKSLRMELLAKDDHIKEMHERTSRMERDITMKRHLIEDLKFRQK 1148
Cdd:TIGR02168 770 LEEAEEELAEAEA-EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1149 VNSESNESFNEMLETLEKKVKSLTEEcsnkkvsvdslkqrLNVAVKEKSQYEQMYQKTKEELEKKDlkmsvliSKLNDTE 1228
Cdd:TIGR02168 849 ELSEDIESLAAEIEELEELIEELESE--------------LEALLNERASLEEALALLRSELEELS-------EELRELE 907
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 87299624 1229 TAMAQIETAASEqLQGLALQSEQVLEGAQKKLLSANEKI-EEFTV---FVKALVNELQSDVHGTRHQIRELKK 1297
Cdd:TIGR02168 908 SKRSELRRELEE-LREKLAQLELRLEGLEVRIDNLQERLsEEYSLtleEAEALENKIEDDEEEARRRLKRLEN 979
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
131-783 |
2.29e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.48 E-value: 2.29e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 131 RRLQATNPDLTQTVSLVVEREKQKSEAKDRkvleiLQVKDSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCD 210
Cdd:TIGR02168 260 AELQELEEKLEELRLEVSELEEEIEELQKE-----LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDE 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 211 LQKKFKDKSQEVKDAKECVQSKEEQN----------RLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDT 280
Cdd:TIGR02168 335 LAEELAELEEKLEELKEELESLEAELeeleaeleelESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLED 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 281 RVKVLEENLIEAKKEIESAQTKynVVSQQLNNKQAELLQKDMDITLIRKELQELQNVYKQNSAHTAQQADLIQQLQALNM 360
Cdd:TIGR02168 415 RRERLQQEIEELLKKLEEAELK--ELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 361 DTQKVLRNQEDVHT--AESMSYQKLYNELHMCF--------ETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQ 430
Cdd:TIGR02168 493 SLERLQENLEGFSEgvKALLKNQSGLSGILGVLselisvdeGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGR 572
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 431 GTAPSLSPHDSDSSHSGKAPLSTLETLMISQKSEIEYLQKKLKVANEKLMANRSCDQDFSEkGTEGKHKEPP-------- 502
Cdd:TIGR02168 573 VTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDN-ALELAKKLRPgyrivtld 651
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 503 ---VKRSRSLSPKSSFMGSEEL---RKLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLqmlhtnyravkEQLKQW 576
Cdd:TIGR02168 652 gdlVRPGGVITGGSAKTNSSILerrREIEELEEKIEELEEKIAELEKALAELRKELEELEEEL-----------EQLRKE 720
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 577 EEDSGMAESRQMKRAEPHQLRQEDSDAVWNELayfKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEKREE 656
Cdd:TIGR02168 721 LEELSRQISALRKDLARLEAEVEQLEERIAQL---SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE 797
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 657 qlFRQHEDAEVKKSTPEKNEKAISEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKEL 736
Cdd:TIGR02168 798 --LKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL 875
|
650 660 670 680
....*....|....*....|....*....|....*....|....*..
gi 87299624 737 EQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEAKALRGKDEE 783
Cdd:TIGR02168 876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE 922
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
154-741 |
5.71e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 60.72 E-value: 5.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 154 KSEAKDRKVLEILqvkdSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKDAKECVQSKE 233
Cdd:COG1196 219 KEELKELEAELLL----LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 234 EQNRLVIKNLEEENERLRtrctDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQLNNK 313
Cdd:COG1196 295 AELARLEQDIARLEERRR----ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 314 QAELLQKDMDITLIRKELQELQN---VYKQNSAHTAQQADLIQQLQALNMDTQKVLRNQEDVHTAESMSYQKLYNELHMC 390
Cdd:COG1196 371 EAELAEAEEELEELAEELLEALRaaaELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 391 FETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESqgtAPSLSPHDSDSSHSGKAPLSTLETLMISQKSEI----- 465
Cdd:COG1196 451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA---AARLLLLLEAEADYEGFLEGVKAALLLAGLRGLagava 527
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 466 ------EYLQKKLKVANEKLMANRSCDQDFSEKGTEGKHKE-----------PPVKRSRSLSPKSSFMGSEELRKLKKAE 528
Cdd:COG1196 528 vligveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAakagratflplDKIRARAALAAALARGAIGAAVDLVASD 607
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 529 RKIENLEKTLQLKS-QENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRAEPHQLRQEDSDAVWNE 607
Cdd:COG1196 608 LREADARYYVLGDTlLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAER 687
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 608 LAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTPEKNEKAI-SEETLQK 686
Cdd:COG1196 688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPpDLEELER 767
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*..
gi 87299624 687 VIE-LENRLKSFEK-NSRKLkEESKRLKKENDFLKSHLkhyqEDSEAREKELEQLLR 741
Cdd:COG1196 768 ELErLEREIEALGPvNLLAI-EEYEELEERYDFLSEQR----EDLEEARETLEEAIE 819
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
149-773 |
3.55e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.07 E-value: 3.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 149 EREKQKSEAKDRKVLEILQVKDSKIQELEQTESVLKQELHDL-VKLKTLVDEENAFLRKELCDL-------QKKFKDKSQ 220
Cdd:TIGR02169 236 ERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELnKKIKDLGEEEQLRVKEKIGELeaeiaslERSIAEKER 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 221 EVKDAKECVQSKEEQ---NRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIE 297
Cdd:TIGR02169 316 ELEDAEERLAKLEAEidkLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLE 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 298 SAQTKYNVVSQQLNNKQAELLQKDMDITLIRKELQELQNVYKQNSAHTAQQADLIQQLQALNMDTQKVLRNQEDVHTAES 377
Cdd:TIGR02169 396 KLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLK 475
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 378 MSYQKLYNELHMC------FETT-----------KSNEVMLR---QSVVNLQGQLFQKEQENVK---------LKEKLEE 428
Cdd:TIGR02169 476 EEYDRVEKELSKLqrelaeAEAQaraseervrggRAVEEVLKasiQGVHGTVAQLGSVGERYATaievaagnrLNNVVVE 555
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 429 SQGTAPSlSPHDSDSSHSGKAPLSTLETLMISQKSE---------------IEYLQKKLKV---------------ANEK 478
Cdd:TIGR02169 556 DDAVAKE-AIELLKRRKAGRATFLPLNKMRDERRDLsilsedgvigfavdlVEFDPKYEPAfkyvfgdtlvvedieAARR 634
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 479 LMANR---SCDQDFSEKG---TEGKHKEP-PVKRSRSLSPKSSFMgSEELRKLKKA-ERKIENLEKTLQLKSQENDELRD 550
Cdd:TIGR02169 635 LMGKYrmvTLEGELFEKSgamTGGSRAPRgGILFSRSEPAELQRL-RERLEGLKRElSSLQSELRRIENRLDELSQELSD 713
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 551 AHEKRKE---RLQMLHTNYRAVKEQLKQWEED-----SGMAESRQMKRAEPHQLRQEDSDAVWNELAYFKRENQELMVQK 622
Cdd:TIGR02169 714 ASRKIGEiekEIEQLEQEEEKLKERLEELEEDlssleQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRI 793
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 623 MTLQDELDELK-MHMSIDKTTI---QELNRCMAEKREEQLFRQHEDAEVKKSTPEKNEKAISEETLQKVI-ELENRLKSF 697
Cdd:TIGR02169 794 PEIQAELSKLEeEVSRIEARLReieQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKeELEEELEEL 873
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 87299624 698 EKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLlrvskdvEHDKSELQTKITALETEVTTLRRQVTE 773
Cdd:TIGR02169 874 EAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK-------RKRLSELKAKLEALEEELSEIEDPKGE 942
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
151-689 |
1.06e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 50.32 E-value: 1.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 151 EKQKSEAKDRKVLEILQVKDSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKDAKE--- 227
Cdd:COG1196 289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEall 368
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 228 CVQSKEEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVS 307
Cdd:COG1196 369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 308 QQLNNKQAELLQKDMDITLIRKELQELQNVYKQNSAHTAQQADLIQQLQALNMDTQKVLRNQEDVHTAESMS--YQKLYN 385
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglAGAVAV 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 386 ELHMCFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDSDSSHSGKAPLSTLETLMISQKSEI 465
Cdd:COG1196 529 LIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDL 608
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 466 EYLQKKLKVANEKLMANRSCDQDFSEKGTEGKHKEPPVKRSRSLSPKSSFMGSEELRKLKKAERKIENLEKTLQLKSQEN 545
Cdd:COG1196 609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 546 DELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRAEPHQLRQEDSDAVWNELAYfkrENQELMVQKMTL 625
Cdd:COG1196 689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAL---EELPEPPDLEEL 765
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 87299624 626 QDELDELKMHM----SIDKTTIQELNRcmAEKREEQLFRQHEDAevkkstpeknEKAIseETLQKVIE 689
Cdd:COG1196 766 ERELERLEREIealgPVNLLAIEEYEE--LEERYDFLSEQREDL----------EEAR--ETLEEAIE 819
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
1147-1269 |
2.69e-05 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 48.67 E-value: 2.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1147 QKVNSESNESFNEM---LETLEKKVKSLTEECSNKKVSVDSLKQRLNvavKEKSQYEQMYQKTKEELEKKdLKMSVLISK 1223
Cdd:PRK00409 508 KKLIGEDKEKLNELiasLEELERELEQKAEEAEALLKEAEKLKEELE---EKKEKLQEEEDKLLEEAEKE-AQQAIKEAK 583
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 87299624 1224 lndtETAMAQIETAASEQLQGLALQSEQVLEGAQKKLLSANEKIEE 1269
Cdd:PRK00409 584 ----KEADEIIKELRQLQKGGYASVKAHELIEARKRLNKANEKKEK 625
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
153-358 |
4.07e-05 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 48.37 E-value: 4.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 153 QKSEAKDRKVLEilQVKDSKIQELEQTESVLKQelhdlvklKTLVDEENAFLRKELCDLQKKFKdksqevkdakecvQSK 232
Cdd:PRK11281 44 QLDALNKQKLLE--AEDKLVQQDLEQTLALLDK--------IDRQKEETEQLKQQLAQAPAKLR-------------QAQ 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 233 EEQNRLVIKNLEEENERLRTRC-TDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQLN 311
Cdd:PRK11281 101 AELEALKDDNDEETRETLSTLSlRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLK 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 87299624 312 NK---------------QAELLQKDMDITLIRKELQ---ELQNVY-KQNSAHTAQQADLIQQLQAL 358
Cdd:PRK11281 181 GGkvggkalrpsqrvllQAEQALLNAQNDLQRKSLEgntQLQDLLqKQRDYLTARIQRLEHQLQLL 246
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
519-1347 |
7.29e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.44 E-value: 7.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 519 EELRKLKKAeRKIENLEKTLQLKSQEndELRDAHEKRKERLQMLHTNYRAVkEQLKQWEEDSGMAESRQMKRAEPHQLRQ 598
Cdd:PTZ00121 1167 EEARKAEDA-KKAEAARKAEEVRKAE--ELRKAEDARKAEAARKAEEERKA-EEARKAEDAKKAEAVKKAEEAKKDAEEA 1242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 599 EDSDAVWNELAYFKRENQELMVQKMTLQDELDElkmhmsiDKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTPEKNEKA 678
Cdd:PTZ00121 1243 KKAEEERNNEEIRKFEEARMAHFARRQAAIKAE-------EARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAK 1315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 679 ISEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLR----VSKDVEHDKSELQ 754
Cdd:PTZ00121 1316 KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKkadaAKKKAEEKKKADE 1395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 755 TKITALET-----EVTTLRRQVTEAKALRGKDEEVVCPEERAHRPTDKAKSEMATtdvrarrcdcKTATTKVKFKAAKRK 829
Cdd:PTZ00121 1396 AKKKAEEDkkkadELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAK----------KKAEEAKKAEEAKKK 1465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 830 CSVGRHHTVLNHSIKVMSHVENLSKDGWEDVSEGSDSETQTfqnlgtiivETSQNISPIEDGRNQKEIDQTEGSCAQQRA 909
Cdd:PTZ00121 1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAA---------EAKKKADEAKKAEEAKKADEAKKAEEAKKA 1536
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 910 MQTYSCEDIKAPQSISHNKNTKKMTFQKKSGSLQKSlhsalparvnrEKCKNLPAQKSSSSTISLRERIVSLQQQNSLLQ 989
Cdd:PTZ00121 1537 DEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKA-----------EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK 1605
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 990 NARRAAEASAKEYKEANEKLLHQQQVsdhrfqtsRQTIKKLTLDLAELRKEKEDLLKkvesssdimslAEEVSRIMAPQI 1069
Cdd:PTZ00121 1606 KMKAEEAKKAEEAKIKAEELKKAEEE--------KKKVEQLKKKEAEEKKKAEELKK-----------AEEENKIKAAEE 1666
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1070 KvttlgpsRSMDLEMKQLQcklknatnELTKQSSNVKSLRMELLAKDDHIKEMHERTSRMERDITMKrhliEDLKFRQKV 1149
Cdd:PTZ00121 1667 A-------KKAEEDKKKAE--------EAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA----EELKKAEEE 1727
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1150 NSESNESFNEMLETLEKKVKSLTEECSNKKVSVDSLKQRLNVAVKEKSQYEQMyqkTKEELEKKDLKMSVLISKlndtet 1229
Cdd:PTZ00121 1728 NKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV---IEEELDEEDEKRRMEVDK------ 1798
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1230 amaqietaaseQLQGLALQSEQVLEGAQKKLLSANEKIEEFTVFVKALVNELQSdvhgTRHQIRELKKMQKSRHACKTST 1309
Cdd:PTZ00121 1799 -----------KIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNM----QLEEADAFEKHKFNKNNENGED 1863
|
810 820 830
....*....|....*....|....*....|....*...
gi 87299624 1310 HKAQTLAASILNISRSDLEEILDTEDELEIEKTKIDIE 1347
Cdd:PTZ00121 1864 GNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIERE 1901
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
150-783 |
1.67e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.21 E-value: 1.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 150 REKQKSEAKDRKVLEILQVKDSKIQELEQTESVLKQELHDLVKLktlVDEENAFLRKELCDLQKKFKDKSQEVKDAKECV 229
Cdd:TIGR02169 230 KEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQL---LEELNKKIKDLGEEEQLRVKEKIGELEAEIASL 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 230 QSKEEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEE---------------------N 288
Cdd:TIGR02169 307 ERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEeledlraeleevdkefaetrdE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 289 LIEAKKEIESAQTKYNVVSQQLNNKQAELLQKDMDITLIRKELQELQNVYKQNSAHTAQQADLIQQLQALNMDTQKVLRN 368
Cdd:TIGR02169 387 LKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 369 QEDVHTAESMSYQKLYNELHMC------FETT-----------KSNEVMLR---QSVVNLQGQLFQKEQENVK------- 421
Cdd:TIGR02169 467 YEQELYDLKEEYDRVEKELSKLqrelaeAEAQaraseervrggRAVEEVLKasiQGVHGTVAQLGSVGERYATaievaag 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 422 --LKEKLEESQGTAPSlSPHDSDSSHSGKAPLSTLETLMISQKSE---------------IEYLQKKLKV---------- 474
Cdd:TIGR02169 547 nrLNNVVVEDDAVAKE-AIELLKRRKAGRATFLPLNKMRDERRDLsilsedgvigfavdlVEFDPKYEPAfkyvfgdtlv 625
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 475 -----ANEKLMANR---SCDQDFSEKG---TEGKHKEP-PVKRSRSLSPKSSFMgSEELRKLKKA-ERKIENLEKTLQLK 541
Cdd:TIGR02169 626 vedieAARRLMGKYrmvTLEGELFEKSgamTGGSRAPRgGILFSRSEPAELQRL-RERLEGLKRElSSLQSELRRIENRL 704
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 542 SQENDELRDAHEKRKE---RLQMLHTNYRAVKEQLKQWEEDSgmaesrqmkraephQLRQEDSDAVWNELAYFKRENQEL 618
Cdd:TIGR02169 705 DELSQELSDASRKIGEiekEIEQLEQEEEKLKERLEELEEDL--------------SSLEQEIENVKSELKELEARIEEL 770
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 619 MVQKMTLQDELDELKMH--MSIDKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTPEKN--EKAIsEETLQKVIELENRL 694
Cdd:TIGR02169 771 EEDLHKLEEALNDLEARlsHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEylEKEI-QELQEQRIDLKEQI 849
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 695 KSFEKnsrklKEESKRLKKENdfLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEA 774
Cdd:TIGR02169 850 KSIEK-----EIENLNGKKEE--LEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSEL 922
|
....*....
gi 87299624 775 KALRGKDEE 783
Cdd:TIGR02169 923 KAKLEALEE 931
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
172-762 |
2.02e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 46.29 E-value: 2.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 172 KIQELEQTESVLK-QELHDLVKLKTLVDEenafLRKELCDLQKK---FKDKSQEVKDAKECVQSKEEQNRLVIKNLEEEN 247
Cdd:PTZ00121 1291 KADEAKKAEEKKKaDEAKKKAEEAKKADE----AKKKAEEAKKKadaAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKA 1366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 248 ERLRTRCTDLLNDLEKLRNQEAHWRKEKhsvdtrvkvleenliEAKKEIESAQTKynvvSQQLNNKQAEllqkdmditli 327
Cdd:PTZ00121 1367 EAAEKKKEEAKKKADAAKKKAEEKKKAD---------------EAKKKAEEDKKK----ADELKKAAAA----------- 1416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 328 RKELQELqnvykQNSAHTAQQADLIQQLQALNMDTQKVLRNQEDVHTAESMsyQKLYNELHMCFETTKSNEvmlrqsvvn 407
Cdd:PTZ00121 1417 KKKADEA-----KKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEA--KKKAEEAKKADEAKKKAE--------- 1480
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 408 lqgqlfqKEQENVKLKEKLEESQGTAPSLSphdsdsshsgkaplstletlmisQKSEIEYLQKKLKVANEKLMANRSCDQ 487
Cdd:PTZ00121 1481 -------EAKKADEAKKKAEEAKKKADEAK-----------------------KAAEAKKKADEAKKAEEAKKADEAKKA 1530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 488 DFSEKGTEGKHKEpPVKRSRSLSPKSSFMGSEELRKLKKAERKIEnlEKTLQLKSQEndELRDAHEKRKERLQMLHTNYR 567
Cdd:PTZ00121 1531 EEAKKADEAKKAE-EKKKADELKKAEELKKAEEKKKAEEAKKAEE--DKNMALRKAE--EAKKAEEARIEEVMKLYEEEK 1605
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 568 AVK-EQLKQWEEDSGMAEsrQMKRAEPHQLRQEDSDAVWNELayfKRENQELMVQKMTLQDELDELKMHMSIDKTTIQEL 646
Cdd:PTZ00121 1606 KMKaEEAKKAEEAKIKAE--ELKKAEEEKKKVEQLKKKEAEE---KKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEA 1680
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 647 NRCMAEKR--EEQLFRQHEDA----EVKKSTPEKNEKA--ISEETLQKVIELENRLKSFEKNSRKlKEESKRLKKENDFL 718
Cdd:PTZ00121 1681 KKAEEDEKkaAEALKKEAEEAkkaeELKKKEAEEKKKAeeLKKAEEENKIKAEEAKKEAEEDKKK-AEEAKKDEEEKKKI 1759
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 87299624 719 KSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALET 762
Cdd:PTZ00121 1760 AHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDI 1803
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
385-805 |
2.23e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 45.88 E-value: 2.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 385 NELHmcfettKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDSDSSHSGKAPLSTLETLMISQKSE 464
Cdd:pfam15921 98 NELH------EKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQ 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 465 IEYLQKKLKVANEKLMANRSCDQDFSEKGTEGKHKEPPVK--RSRSLSPKSSFMGSE---ELRKLKKAERKIENLEKTLQ 539
Cdd:pfam15921 172 IEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMStmHFRSLGSAISKILREldtEISYLKGRIFPVEDQLEALK 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 540 LKSQENDE-LRDAHEKRKERLQMLHTnyravkeqlkqwEEDSGMAESRQMKRAEPHQLRQEdsdavwNELAYFKRENQEL 618
Cdd:pfam15921 252 SESQNKIElLLQQHQDRIEQLISEHE------------VEITGLTEKASSARSQANSIQSQ------LEIIQEQARNQNS 313
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 619 MVQKmtlqdELDELKMHMSIDKTTIQELNRcMAEKREEQLFRQHEDAEVKKSTPEKNEKAISEETLQKVIELENRLKSFE 698
Cdd:pfam15921 314 MYMR-----QLSDLESTVSQLRSELREAKR-MYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLH 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 699 KNSRKL---KEESKRL---KKENDFLKSHLKHYQEDSEAREKELEQLLRVSKD-----VEHDKSELQTKITALEtEVTTL 767
Cdd:pfam15921 388 KREKELsleKEQNKRLwdrDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSecqgqMERQMAAIQGKNESLE-KVSSL 466
|
410 420 430
....*....|....*....|....*....|....*...
gi 87299624 768 RRQVTEAKALRGKDEEVVCPEERAHRPTDKAKSEMATT 805
Cdd:pfam15921 467 TAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTAS 504
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
512-783 |
3.67e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.06 E-value: 3.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 512 KSSFMGSEELRKLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRA 591
Cdd:TIGR02169 220 KREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGEL 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 592 EPHQLRQEDSdavwneLAYFKRENQELMVQKMTLQDELDELKmhmsidkTTIQELNRcmaEKREEQLFRQHEDAEVKKST 671
Cdd:TIGR02169 300 EAEIASLERS------IAEKERELEDAEERLAKLEAEIDKLL-------AEIEELER---EIEEERKRRDKLTEEYAELK 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 672 PEKNEKaiseetlqkVIELENRLKSFEKNSRKLKEESKR---LKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEH 748
Cdd:TIGR02169 364 EELEDL---------RAELEEVDKEFAETRDELKDYREKlekLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA 434
|
250 260 270
....*....|....*....|....*....|....*
gi 87299624 749 DKSELQTKITALETEVTTLRRQVTEAKALRGKDEE 783
Cdd:TIGR02169 435 KINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQ 469
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
519-780 |
3.94e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 45.05 E-value: 3.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 519 EELRKLKKAERKIENL----EKTLQLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRAEPH 594
Cdd:PRK03918 179 ERLEKFIKRTENIEELikekEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 595 QLRQEDSDAVwNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRcmAEKREEQLFRQHEDAEVKKSTPEK 674
Cdd:PRK03918 259 EKIRELEERI-EELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELRE--IEKRLSRLEEEINGIEERIKELEE 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 675 NEKAIsEETLQKVIELENRLKSFEKNSRKLkEESKRLKKENDFLKSHLKHYQedSEAREKELEQLLRVSKDVEHDKSELQ 754
Cdd:PRK03918 336 KEERL-EELKKKLKELEKRLEELEERHELY-EEAKAKKEELERLKKRLTGLT--PEKLEKELEELEKAKEEIEEEISKIT 411
|
250 260
....*....|....*....|....*.
gi 87299624 755 TKITALETEVTTLRRQVTEAKALRGK 780
Cdd:PRK03918 412 ARIGELKKEIKELKKAIEELKKAKGK 437
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
139-361 |
4.12e-04 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 44.90 E-value: 4.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 139 DLTQTVSLVVEREKQKSEAKDRKvleilqvkdskiQELEQTESVLKQELHDLVKLKTLVDEENA--FLRKELCDLQKKFK 216
Cdd:PRK11281 64 DLEQTLALLDKIDRQKEETEQLK------------QQLAQAPAKLRQAQAELEALKDDNDEETRetLSTLSLRQLESRLA 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 217 DKSQEVKDAKECVQskeEQNRLVIkNLEEENERLRTRCTDLLNDLEKLRNQeahwrkeKHSVDTRVKVL---EENLIEAK 293
Cdd:PRK11281 132 QTLDQLQNAQNDLA---EYNSQLV-SLQTQPERAQAALYANSQRLQQIRNL-------LKGGKVGGKALrpsQRVLLQAE 200
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 87299624 294 KEIESAQTKYNVVSQQLNNKQAELLQKDMD-----ITLIRKELQELQNV----YKQNSAHTAQQADLIQQLQALNMD 361
Cdd:PRK11281 201 QALLNAQNDLQRKSLEGNTQLQDLLQKQRDyltarIQRLEHQLQLLQEAinskRLTLSEKTVQEAQSQDEAARIQAN 277
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
148-775 |
5.75e-04 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 44.33 E-value: 5.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 148 VEREKQKSEAKDRKVLEILQVKDSKIQELE-QTESVLKQELHDLVKLKTLVDEENAflRKELCDLQKKFKDKSQEVKDAK 226
Cdd:pfam05483 97 IEAELKQKENKLQENRKIIEAQRKAIQELQfENEKVSLKLEEEIQENKDLIKENNA--TRHLCNLLKETCARSAEKTKKY 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 227 EcvqSKEEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSvdtRVKVLEEnliEAKKEIESAQTKYNVV 306
Cdd:pfam05483 175 E---YEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEMHFKLKEDHE---KIQHLEE---EYKKEINDKEKQVSLL 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 307 SQQLNNKQaellQKDMDITLIRKElqelqnvykqnSAHTAQQADLIQQLQALNMdtqKVLRNQEDVHTAEsmsyqklYNE 386
Cdd:pfam05483 246 LIQITEKE----NKMKDLTFLLEE-----------SRDKANQLEEKTKLQDENL---KELIEKKDHLTKE-------LED 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 387 LHMCFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDsdsshsgKAPLSTLETLMISQKSEIE 466
Cdd:pfam05483 301 IKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEF-------EATTCSLEELLRTEQQRLE 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 467 YLQKKLKVANEKLMaNRSCDQDFSEKGTEGKHKEppvkrsrsLSPKSSFMGSEElrKLKKAERKIENLEKTLQLKSQEND 546
Cdd:pfam05483 374 KNEDQLKIITMELQ-KKSSELEEMTKFKNNKEVE--------LEELKKILAEDE--KLLDEKKQFEKIAEELKGKEQELI 442
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 547 ELRDAHEKRKERLQMLHTNYRAVKEQ-LKQWEEDSGMAESRQMKRAEphqlrqedsdavwnelayFKRENQELMVQKMTL 625
Cdd:pfam05483 443 FLLQAREKEIHDLEIQLTAIKTSEEHyLKEVEDLKTELEKEKLKNIE------------------LTAHCDKLLLENKEL 504
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 626 QDELDELKMHMsidKTTIQELNRCmaEKREEQLFRQHEDAEVKKSTPEKNEKAISEETLQKVIELENRLKSFEKNSRKLK 705
Cdd:pfam05483 505 TQEASDMTLEL---KKHQEDIINC--KKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIE 579
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 706 EESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEAK 775
Cdd:pfam05483 580 YEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAK 649
|
|
| Golgin_A5 |
pfam09787 |
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ... |
164-310 |
9.98e-04 |
|
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.
Pssm-ID: 462900 [Multi-domain] Cd Length: 305 Bit Score: 42.82 E-value: 9.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 164 EILQVKDSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKDAKECVQSKEEQNRLVIKNL 243
Cdd:pfam09787 51 ELRQERDLLREEIQKLRGQIQQLRTELQELEAQQQEEAESSREQLQELEEQLATERSARREAEAELERLQEELRYLEEEL 130
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 244 EEENERLRTRCTDLLNDLEKLRNQ---EAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQL 310
Cdd:pfam09787 131 RRSKATLQSRIKDREAEIEKLRNQltsKSQSSSSQSELENRLHQLTETLIQKQTMLEALSTEKNSLVLQL 200
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
259-478 |
1.07e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.21 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 259 NDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQLNNKQAELLQKDMDITLIRKELQELQNVY 338
Cdd:COG4942 27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 339 kqnsahtaqqADLIQQLQAL-NMDTQKVLRNQEDVHTAE-SMSYQKLYN----ELHMCFETTKSNEVMLRQSVVNLQGQL 412
Cdd:COG4942 107 ----------AELLRALYRLgRQPPLALLLSPEDFLDAVrRLQYLKYLAparrEQAEELRADLAELAALRAELEAERAEL 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 87299624 413 FQKEQENVKLKEKLEESQGTAPSLSPHDSDSSHSGKAPLSTLETLMISQKSEIEYLQKKLKVANEK 478
Cdd:COG4942 177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
519-776 |
1.12e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.57 E-value: 1.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 519 EELRKLKKAERKIENLEKTLQLKSQEN-----DELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRAEP 593
Cdd:pfam17380 306 EEKAREVERRRKLEEAEKARQAEMDRQaaiyaEQERMAMERERELERIRQEERKRELERIRQEEIAMEISRMRELERLQM 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 594 HqlRQEDSDAVWNEL-AYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEK-------REEQLFRQHEDA 665
Cdd:pfam17380 386 E--RQQKNERVRQELeAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERaremervRLEEQERQQQVE 463
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 666 EVKKSTPEKNEKAIS---EETLQKVIELENRL---KSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQl 739
Cdd:pfam17380 464 RLRQQEEERKRKKLElekEKRDRKRAEEQRRKileKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEER- 542
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 87299624 740 lRVSKDVEHDK---------SELQTKITALETEVTTLRRQVTEAKA 776
Cdd:pfam17380 543 -RKQQEMEERRriqeqmrkaTEERSRLEAMEREREMMRQIVESEKA 587
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
618-767 |
1.42e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 42.99 E-value: 1.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 618 LMVQKM------TLQDELDElkmhmsidktTIQELnrcmaekREEQLFrQHEDAEVKKSTpEKNEKAISEetLQKVIELE 691
Cdd:PRK05771 1 LAPVRMkkvlivTLKSYKDE----------VLEAL-------HELGVV-HIEDLKEELSN-ERLRKLRSL--LTKLSEAL 59
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 87299624 692 NRLKSFEKNSRKLKEESKRLKKENdflkshlkhYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEVTTL 767
Cdd:PRK05771 60 DKLRSYLPKLNPLREEKKKVSVKS---------LEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERL 126
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
241-785 |
2.08e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 42.74 E-value: 2.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 241 KNLEEENERLrTRCTDLLNDLEK-----------------LRNQEAHWrkEKHSVDTRVKVLEENLIEAKKEIESAQTKY 303
Cdd:TIGR02168 179 RKLERTRENL-DRLEDILNELERqlkslerqaekaerykeLKAELREL--ELALLVLRLEELREELEELQEELKEAEEEL 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 304 NVVSQQLNNKQAELLQKDMDITLIRKELQELQNVYKqnsAHTAQQADLIQQLQALNMDTQKVLRNQEdvhtaesmsyqkl 383
Cdd:TIGR02168 256 EELTAELQELEEKLEELRLEVSELEEEIEELQKELY---ALANEISRLEQQKQILRERLANLERQLE------------- 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 384 ynELHMCFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLsphdsdsshsgKAPLSTLETLMISQKS 463
Cdd:TIGR02168 320 --ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEEL-----------ESRLEELEEQLETLRS 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 464 EIEYLQKKLKVANEKL--------MANRSCDQDFSEKGTEGKHKEPPVKRSRSLSPKSSFMGSEELRK-LKKAERKIENL 534
Cdd:TIGR02168 387 KVAQLELQIASLNNEIerlearleRLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEeLERLEEALEEL 466
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 535 EKTLQLKSQENDELRDAHEKRKERLQMLHT-------NYRAVKEQLKQWEEDSGMAE--SRQMKRAEPHQLRQE------ 599
Cdd:TIGR02168 467 REELEEAEQALDAAERELAQLQARLDSLERlqenlegFSEGVKALLKNQSGLSGILGvlSELISVDEGYEAAIEaalggr 546
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 600 -------DSDAVWNELAYFKRENQ------------------ELMVQKMTLQDELDELKMHMSIDK-------------- 640
Cdd:TIGR02168 547 lqavvveNLNAAKKAIAFLKQNELgrvtflpldsikgteiqgNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggvl 626
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 641 --TTIQELNRCMAEKREEQLF---------------RQHEDAEV----KKSTPEKNEKAIsEETLQKVIELENRLKSFEK 699
Cdd:TIGR02168 627 vvDDLDNALELAKKLRPGYRIvtldgdlvrpggvitGGSAKTNSsileRRREIEELEEKI-EELEEKIAELEKALAELRK 705
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 700 NSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEAKALRG 779
Cdd:TIGR02168 706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785
|
....*.
gi 87299624 780 KDEEVV 785
Cdd:TIGR02168 786 ELEAQI 791
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
154-734 |
2.26e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 42.36 E-value: 2.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 154 KSEAKDRKVLEILQVKDSKIQELE---QTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKD---AKE 227
Cdd:PRK03918 159 DYENAYKNLGEVIKEIKRRIERLEkfiKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEleeLKE 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 228 CVQSKEEQNRLVIKNLEEENERLR---TRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLE--ENLIEAKKEIESAQTK 302
Cdd:PRK03918 239 EIEELEKELESLEGSKRKLEEKIReleERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEfyEEYLDELREIEKRLSR 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 303 YNVVSQQLNNKQAELLQKDMDITLIRKELQELQNVYkqnsahtaqqADLIQQLQALNMDTQKVLRNQEDVHTAESMSYQK 382
Cdd:PRK03918 319 LEEEINGIEERIKELEEKEERLEELKKKLKELEKRL----------EELEERHELYEEAKAKKEELERLKKRLTGLTPEK 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 383 LYNELHMcFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDSDSSHSGKAPLSTLETLMIS-Q 461
Cdd:PRK03918 389 LEKELEE-LEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEkE 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 462 KSEIEYLQKKLKVANEKLMANRSCDQDFSEKGTEGKHKEPPVKRSRSLSPKSSFMGSEELRKLKKAERKIENLEKTLQLK 541
Cdd:PRK03918 468 LKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKE 547
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 542 SQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRAEPHQLRqedsdavWNELAYFKRENQELMVQ 621
Cdd:PRK03918 548 LEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNE-------YLELKDAEKELEREEKE 620
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 622 KMTLQDELDELKMHMSIDKTTIQELnrcmaEKREEQLFRQHEDAEVKKSTPEKNEKAISEETLQKVIE-LENRLKSFEKN 700
Cdd:PRK03918 621 LKKLEEELDKAFEELAETEKRLEEL-----RKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEeLEKRREEIKKT 695
|
570 580 590
....*....|....*....|....*....|....
gi 87299624 701 SRKLKEESKRLKKENDFLKSHLKHYQEDSEAREK 734
Cdd:PRK03918 696 LEKLKEELEEREKAKKELEKLEKALERVEELREK 729
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
528-1303 |
2.40e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 42.65 E-value: 2.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 528 ERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTN---YRAVKEQLKQWEEDSGMAESRQMKRAEphQLRQEDSDAV 604
Cdd:pfam02463 169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAkkaLEYYQLKEKLELEEEYLLYLDYLKLNE--ERIDLLQELL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 605 WNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEKREEQLFRQHEDAEVKKstpEKNEKAISEETL 684
Cdd:pfam02463 247 RDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVD---DEEKLKESEKEK 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 685 QKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEV 764
Cdd:pfam02463 324 KKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEE 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 765 TTLRRQVTEAKALRGKDEEVVCPEERAHRPTDKAKSEMATTDVRARRCDCKTATTKVKFKAAKRKCSVGRHHTVLNHSIK 844
Cdd:pfam02463 404 EKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQ 483
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 845 VMSHVENLSKDGWEDVSEGSDSETQTFQNLGTIIVETSQNISPIEDGRNQKEIDQTEGSCAQQRAMQTYSCEDIKAPQSI 924
Cdd:pfam02463 484 EQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 925 SHNKNTKKMTFQKKSGSLQKSLHSALPARVNREKCKNLPAQKSSSSTISLRERiVSLQQQNSLLQNARRAAEASAKEYKE 1004
Cdd:pfam02463 564 QKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEAD-EDDKRAKVVEGILKDTELTKLKESAK 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1005 ANEKLLhQQQVSDHRFQTSRQTIKKLTLDLAELRKEKEDLLKKVESSSDIMSLAEEVSRIMAPQIKVTTlgpsrsmdlEM 1084
Cdd:pfam02463 643 AKESGL-RKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKE---------EL 712
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1085 KQLQCKLKNATNELTKQSSNVKSLRMELLAKDDHIKEMHERTSRMERDITMKRHLIEDLKFRQKVNSESNESFNEMLETL 1164
Cdd:pfam02463 713 KKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEK 792
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1165 EKKVKSLTEECSNKKVSVDSLKQRLNVAVKEKSQYEQMYQKTKEELEkKDLKMSVLISKLNDTETAMAQIETAASEQLQG 1244
Cdd:pfam02463 793 EEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELA-LELKEEQKLEKLAEEELERLEEEITKEELLQE 871
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*....
gi 87299624 1245 LALQSEQVLEGAQKKLLSanEKIEEFTVFVKALVNELQSDVHGTRHQIRELKKMQKSRH 1303
Cdd:pfam02463 872 LLLKEEELEEQKLKDELE--SKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAE 928
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
285-795 |
2.80e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 42.26 E-value: 2.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 285 LEENLIEAKKEIESAQTKYnvvsQQLNNKQAELLQKDMDITLIRKELQELQNvykQNSAHTAQQADLIQQLQALnmdtqK 364
Cdd:TIGR00618 227 ELKHLREALQQTQQSHAYL----TQKREAQEEQLKKQQLLKQLRARIEELRA---QEAVLEETQERINRARKAA-----P 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 365 VLRNQEDVHTAEsMSYQKLYNELhmcfettksnevmlrQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDSDSS 444
Cdd:TIGR00618 295 LAAHIKAVTQIE-QQAQRIHTEL---------------QSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIR 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 445 HSGKAPLSTLETLMiSQKSEIEYLQKKLKVANEKLMANRSCDQDFSEKGTEGKHKEPPVKRSRSLSPKSSFMGSEELRKL 524
Cdd:TIGR00618 359 DAHEVATSIREISC-QQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQ 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 525 KKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTnyravKEQLKQWEEDSGMAESrqmKRAEPHQLRQEDSDAV 604
Cdd:TIGR00618 438 RYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQT-----KEQIHLQETRKKAVVL---ARLLELQEEPCPLCGS 509
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 605 WNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELnrcmaekreeqlfrqheDAEVKKSTPEKNEKAISEETL 684
Cdd:TIGR00618 510 CIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQL-----------------TSERKQRASLKEQMQEIQQSF 572
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 685 QKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEV 764
Cdd:TIGR00618 573 SILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQ 652
|
490 500 510
....*....|....*....|....*....|.
gi 87299624 765 TTLRRQVTEAKALRGKDEEVVCPEERAHRPT 795
Cdd:TIGR00618 653 LTLTQERVREHALSIRVLPKELLASRQLALQ 683
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
157-335 |
2.95e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.06 E-value: 2.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 157 AKDRKVLEILQVKDSKIQELEQTESVLKQELHDLvklktlvdeenaflRKELCDLQKKFKDKSQEVKDAKECVQSKEEQn 236
Cdd:COG1579 3 PEDLRALLDLQELDSELDRLEHRLKELPAELAEL--------------EDELAALEARLEAAKTELEDLEKEIKRLELE- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 237 rlvIKNLEEENERLRTRctdlLNDLEKLRNQEAHwRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQLNNKQAE 316
Cdd:COG1579 68 ---IEEVEARIKKYEEQ----LGNVRNNKEYEAL-QKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAE 139
|
170 180
....*....|....*....|...
gi 87299624 317 LLQK----DMDITLIRKELQELQ 335
Cdd:COG1579 140 LEEKkaelDEELAELEAELEELE 162
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1036-1387 |
2.96e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 41.97 E-value: 2.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1036 ELRKEKEDLLKKVESSSDIMSLAEEVSRIMAPQIKVTTLGPSRSMDLEMKqlQCKLKNATNELTKQSSNVKSLRMELLAK 1115
Cdd:PRK03918 173 EIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREE--LEKLEKEVKELEELKEEIEELEKELESL 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1116 DDHIKEMHERTSRMERDITMKRHLIEDLKFRQKvNSESNESFNEMLETLEKKVKSLTEECSNKKVSVDSLKQRLNV---A 1192
Cdd:PRK03918 251 EGSKRKLEEKIRELEERIEELKKEIEELEEKVK-ELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGieeR 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1193 VKEKSQYEQMYQKTKEELEKKDLKMSVLISKLNDTETAMaQIETAASEQLQGLALQSEQVLEGAQKKLLSANEKIEEFTV 1272
Cdd:PRK03918 330 IKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAK-AKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEIS 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1273 FVKALVNELQSDVHGTRHQIRELKKMQKSRHACK---TSTHKAQTLAASILNISR--SDLEEILDTEDELEIEKTKIDIE 1347
Cdd:PRK03918 409 KITARIGELKKEIKELKKAIEELKKAKGKCPVCGrelTEEHRKELLEEYTAELKRieKELKEIEEKERKLRKELRELEKV 488
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 87299624 1348 NDKEWMLYIQKLLEGQLPFASYLLEAV-LEKIKENKKLTEG 1387
Cdd:PRK03918 489 LKKESELIKLKELAEQLKELEEKLKKYnLEELEKKAEEYEK 529
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
519-784 |
3.07e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 42.23 E-value: 3.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 519 EELR-KLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEdsgmaesrqmkraephqlr 597
Cdd:COG1196 270 EELRlELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE------------------- 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 598 qedsdavwnELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTpeknek 677
Cdd:COG1196 331 ---------ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA------ 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 678 aisEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKI 757
Cdd:COG1196 396 ---AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
|
250 260
....*....|....*....|....*..
gi 87299624 758 TALETEVTTLRRQVTEAKALRGKDEEV 784
Cdd:COG1196 473 ALLEAALAELLEELAEAAARLLLLLEA 499
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
149-1065 |
3.72e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 41.97 E-value: 3.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 149 EREKQKSEAKDRKVLEIL----QVKDSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKD 224
Cdd:TIGR02168 213 ERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYA 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 225 AKECVQSKEEQNRLV---IKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQT 301
Cdd:TIGR02168 293 LANEISRLEQQKQILrerLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELES 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 302 KYNVVSQQLNNKQAELLQKDMDITLIRKELQELQNvYKQNSAHTAQQADLIQQLQALNMDTQKVLRNQEDVhtaesmsyq 381
Cdd:TIGR02168 373 RLEELEEQLETLRSKVAQLELQIASLNNEIERLEA-RLERLEDRRERLQQEIEELLKKLEEAELKELQAEL--------- 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 382 klyNELHMCFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDSDSSHSGKAPLSTLE-----T 456
Cdd:TIGR02168 443 ---EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKnqsglS 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 457 LMISQKSEIEYLQKKLKVANEKLMANRSCD------------QDFSEKGTEGK----------HKEPPVKRSRSLSPKSS 514
Cdd:TIGR02168 520 GILGVLSELISVDEGYEAAIEAALGGRLQAvvvenlnaakkaIAFLKQNELGRvtflpldsikGTEIQGNDREILKNIEG 599
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 515 FMGSeeLRKLKKAERKIENLEKTLQLKSQENDELRDAHEKRKErlqmLHTNYRAVKEQLKQWEEDSGMAESRQMKRAEPH 594
Cdd:TIGR02168 600 FLGV--AKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKK----LRPGYRIVTLDGDLVRPGGVITGGSAKTNSSIL 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 595 QLRQEdSDAVWNELAYFKRENQELMVQKMTLQDELDELkmhmsidkttiqelnrcmaEKREEQLFRQHEDAEvkkstpek 674
Cdd:TIGR02168 674 ERRRE-IEELEEKIEELEEKIAELEKALAELRKELEEL-------------------EEELEQLRKELEELS-------- 725
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 675 nekaiseetlQKVIELENRLKSFEKNSRKLKEESKRLKKEndflkshLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQ 754
Cdd:TIGR02168 726 ----------RQISALRKDLARLEAEVEQLEERIAQLSKE-------LTELEAEIEELEERLEEAEEELAEAEAEIEELE 788
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 755 TKITALETEVTTLRRQVTEAKAlrgkdeEVVCPEERAHRPTDKAKSEmattdvrarrcdcktattkvkfkaAKRKCSVGR 834
Cdd:TIGR02168 789 AQIEQLKEELKALREALDELRA------ELTLLNEEAANLRERLESL------------------------ERRIAATER 838
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 835 HHTVLNHSIKVMSHVENLSKDGWEDVSEGSDSETQTFQNLGTIIVETSQNISPIEDGRNQKEIDQTEGSCAQQRAMQtys 914
Cdd:TIGR02168 839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRR--- 915
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 915 ceDIKAPQSISHNKNTKKMTFQKKSGSLQKSLHSAlpARVNREKCKNLPAQKSSSSTiSLRERIVSLQQQNSLLQNARRA 994
Cdd:TIGR02168 916 --ELEELREKLAQLELRLEGLEVRIDNLQERLSEE--YSLTLEEAEALENKIEDDEE-EARRRLKRLENKIKELGPVNLA 990
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 87299624 995 AEAsakEYKEANEkllhqqqvsdhRFQtsrqtikkltldlaELRKEKEDLLKKVEsssDIMSLAEEVSRIM 1065
Cdd:TIGR02168 991 AIE---EYEELKE-----------RYD--------------FLTAQKEDLTEAKE---TLEEAIEEIDREA 1030
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
149-320 |
3.92e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.85 E-value: 3.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 149 EREKQKSEAKDRKVLEILQVKDSKIQELEQTESVLKQELHDLVKLKTLVDEEnaflRKELCDLQKKFKDKSQEVKDAKEC 228
Cdd:COG1196 322 EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE----LAEAEEELEELAEELLEALRAAAE 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 229 VQSKEEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQ 308
Cdd:COG1196 398 LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477
|
170
....*....|..
gi 87299624 309 QLNNKQAELLQK 320
Cdd:COG1196 478 ALAELLEELAEA 489
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
150-322 |
4.29e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.68 E-value: 4.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 150 REKQKSEAKDRKVLEILQVKDSKIQELEQTESVLKQELHDLVKLKTLVDeenafLRKELCDLQKKFKDKSQEVKDAkecv 229
Cdd:COG4717 81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLP-----LYQELEALEAELAELPERLEEL---- 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 230 qskeEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQ-EAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQ 308
Cdd:COG4717 152 ----EERLEELRELEEELEELEAELAELQEELEELLEQlSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEE 227
|
170
....*....|....
gi 87299624 309 QLNNKQAELLQKDM 322
Cdd:COG4717 228 ELEQLENELEAAAL 241
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
522-761 |
4.46e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 41.35 E-value: 4.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 522 RKLKKAERKIENLEKTLQLKSQENDELrdahekrKERLQMLHTNYRAVKEQLKQWEEdsGMAESRQMKRAEPHQLRQEDS 601
Cdd:pfam10174 394 RKINVLQKKIENLQEQLRDKDKQLAGL-------KERVKSLQTDSSNTDTALTTLEE--ALSEKERIIERLKEQREREDR 464
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 602 DAVwNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMaekreeqlfrqhedaeVKKSTPEKNEKAISE 681
Cdd:pfam10174 465 ERL-EELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSG----------------LKKDSKLKSLEIAVE 527
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 682 ETLQKVIELENRLK---SFEKNSRKLKEESKRLKKendfLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKIT 758
Cdd:pfam10174 528 QKKEECSKLENQLKkahNAEEAVRTNPEINDRIRL----LEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIA 603
|
...
gi 87299624 759 ALE 761
Cdd:pfam10174 604 ELE 606
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
558-1270 |
5.11e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 41.36 E-value: 5.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 558 RLQMLHTNYRA--VKEQLKQWEEDSGMAESRQ---MKRAEPHQLRQE---DSDAVWNELAYFKRENQELMVQKMTLQDE- 628
Cdd:pfam12128 259 RLSHLHFGYKSdeTLIASRQEERQETSAELNQllrTLDDQWKEKRDElngELSAADAAVAKDRSELEALEDQHGAFLDAd 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 629 LDELKMHMSIDKTTIQELNrcMAEKREEQLFRQHEDAEVKKstpEKNEKAISEETLQKVIELENRL-KSFEKNSRKLKEE 707
Cdd:pfam12128 339 IETAAADQEQLPSWQSELE--NLEERLKALTGKHQDVTAKY---NRRRSKIKEQNNRDIAGIKDKLaKIREARDRQLAVA 413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 708 SKRLKKENDFLKShlKHYQEDSEAREKELEQLLRVSkdvehDKSELQTKITALETEVTTLRRQVTEAKALRGKDEEVVCP 787
Cdd:pfam12128 414 EDDLQALESELRE--QLEAGKLEFNEEEYRLKSRLG-----ELKLRLNQATATPELLLQLENFDERIERAREEQEAANAE 486
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 788 EERAHRPTDKAKSEMATTDVRARRCDcktattkvkFKAAKRKCSVGRHHTVLNHSIKVMSHVENLSKDGWEdvsegsdse 867
Cdd:pfam12128 487 VERLQSELRQARKRRDQASEALRQAS---------RRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWE--------- 548
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 868 tqtfQNLGTIIvetsqniSPIEDGRNQKEIDQTEGSCAQQRAMQ--TYSCEDIKAPQSISHNKNTKKMTFQKKSG----- 940
Cdd:pfam12128 549 ----QSIGKVI-------SPELLHRTDLDPEVWDGSVGGELNLYgvKLDLKRIDVPEWAASEEELRERLDKAEEAlqsar 617
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 941 SLQKSLHSAL-PARVNREKCK---NLPAQKSSSSTISLRERIVSLQQQNSLLQNARRAAEASAKEYKEaneKLLHQQQVS 1016
Cdd:pfam12128 618 EKQAAAEEQLvQANGELEKASreeTFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLN---SLEAQLKQL 694
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1017 DHRFQTSRQTIKKltlDLAELRKEKEDLLKKVESSSDImSLAEEVSRIMAPQIkvttlgpsrSMDLEMKQLQCKLKNATN 1096
Cdd:pfam12128 695 DKKHQAWLEEQKE---QKREARTEKQAYWQVVEGALDA-QLALLKAAIAARRS---------GAKAELKALETWYKRDLA 761
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1097 ELTKQSSNVKSLRMEllakddhIKEMHERTSRMERditmkrhliedlkFRQKVNsesnESFNEMLETLEKKVKSLTEECS 1176
Cdd:pfam12128 762 SLGVDPDVIAKLKRE-------IRTLERKIERIAV-------------RRQEVL----RYFDWYQETWLQRRPRLATQLS 817
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 1177 NKKVSVDSLKQRLNVAVKEKSQYEQMYQKTKEELEKKDLKMSVLISKLNDTETAMAQI-ETAASEQLQGLALQSEQVLEG 1255
Cdd:pfam12128 818 NIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLkEDANSEQAQGSIGERLAQLED 897
|
730
....*....|....*
gi 87299624 1256 AQKKLLSANEKIEEF 1270
Cdd:pfam12128 898 LKLKRDYLSESVKKY 912
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
150-389 |
5.78e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 41.26 E-value: 5.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 150 REKQKSEAKDRKVLEILQVKDSKIQELE-------QTESVLKQELHDLVKLKTLVDEEnaflrkelcdlQKKFKDKSQEV 222
Cdd:pfam17380 354 RQEERKRELERIRQEEIAMEISRMRELErlqmerqQKNERVRQELEAARKVKILEEER-----------QRKIQQQKVEM 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 223 KDA-KECVQSKEEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTrvkvleenliEAKKEIESAQT 301
Cdd:pfam17380 423 EQIrAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEK----------EKRDRKRAEEQ 492
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 302 KYNVVSQQLNNKQAELLQKDMDITLIRKELQELQN-VYKQNSAHTAQQADLIQQlqalNMDTQKVLRNQEDVHTAESMSY 380
Cdd:pfam17380 493 RRKILEKELEERKQAMIEEERKRKLLEKEMEERQKaIYEEERRREAEEERRKQQ----EMEERRRIQEQMRKATEERSRL 568
|
....*....
gi 87299624 381 QKLYNELHM 389
Cdd:pfam17380 569 EAMEREREM 577
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
510-742 |
6.03e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.91 E-value: 6.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 510 SPKSSFMGSEELRKLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQmK 589
Cdd:COG4717 34 AGKSTLLAFIRAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAEL-E 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 590 RAEPHQLRQEDSDAVWNELAYFKRENQELMvqkmTLQDELDELKMHMsidkTTIQELNRCMAEKREEQLFRQHEDAEVKK 669
Cdd:COG4717 113 ELREELEKLEKLLQLLPLYQELEALEAELA----ELPERLEELEERL----EELRELEEELEELEAELAELQEELEELLE 184
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 87299624 670 STPEKNEKAIsEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEdsEAREKELEQLLRV 742
Cdd:COG4717 185 QLSLATEEEL-QDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAAL--EERLKEARLLLLI 254
|
|
| COG4026 |
COG4026 |
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General ... |
684-763 |
6.49e-03 |
|
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General function prediction only];
Pssm-ID: 443204 [Multi-domain] Cd Length: 287 Bit Score: 40.10 E-value: 6.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 684 LQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETE 763
Cdd:COG4026 127 IPEYNELREELLELKEKIDEIAKEKEKLTKENEELESELEELREEYKKLREENSILEEEFDNIKSEYSDLKSRFEELLKK 206
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
584-778 |
6.60e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 40.65 E-value: 6.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 584 ESRQMKRAEPHQLRQEDSDAVWNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNR----------CMAEK 653
Cdd:pfam07888 37 EECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEkykelsasseELSEE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 654 ReEQLFRQHEDAEVKKSTPEKNEKAISEETLQKVIELENRLKSFEKNSRKLKEEskrlKKENDFLKSHLKHYQEDSEARE 733
Cdd:pfam07888 117 K-DALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEE----EAERKQLQAKLQQTEEELRSLS 191
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 87299624 734 KELEQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEAKALR 778
Cdd:pfam07888 192 KEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALL 236
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
546-794 |
9.28e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 40.67 E-value: 9.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 546 DELRDAHEKRK--ERLQMLHTNYRAVKEQLkqweedsgmAESRQMKRAEPHQLRQEDSDAVWNELAYFKRENQELMVQKM 623
Cdd:COG4913 242 EALEDAREQIEllEPIRELAERYAAARERL---------AELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELE 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 624 TLQDELDElkmhmsidkttiqelnrcmAEKREEQLFRQHEDAEVKKSTPEKNEKAISEETLQkviELENRLKSFEKNSRK 703
Cdd:COG4913 313 RLEARLDA-------------------LREELDELEAQIRGNGGDRLEQLEREIERLERELE---ERERRRARLEALLAA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87299624 704 LKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQ----LLRVSKDVEHDKSELQTKITALET-------EVTTLRRQVt 772
Cdd:COG4913 371 LGLPLPASAEEFAALRAEAAALLEALEEELEALEEalaeAEAALRDLRRELRELEAEIASLERrksnipaRLLALRDAL- 449
|
250 260 270
....*....|....*....|....*....|
gi 87299624 773 eAKALRGKDEEV--------VCPEERAHRP 794
Cdd:COG4913 450 -AEALGLDEAELpfvgelieVRPEEERWRG 478
|
|
| |
