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Conserved domains on  [gi|442628159|ref|NP_788072|]
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cytoplasmic linker protein 190, isoform P [Drosophila melanogaster]

Protein Classification

kinesin family protein; PEPP family PH domain-containing protein( domain architecture ID 13652248)

kinesin family protein is a microtubule-dependent molecular motor that plays an important role in intracellular transport and in cell division and has ATPase-containing motor domain; similar to carboxy-terminal kinesins that contains a C-terminal domain responsible for the motor activity (it hydrolyzes ATP and binds microtubules)| PEPP (phosphoinositol 3-phosphate-binding protein) family PH (pleckstrin homology) domain-containing protein similar to PH domain region of vertebrate pleckstrin homology domain-containing family A member 4/5/6/7

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 172-239 9.54e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.44  E-value: 9.54e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442628159   172 VGDRVIVSsgfGSRPGILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFVPIAKV 239
Cdd:pfam01302    1 VGDRVEVP---GGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 58-122 6.18e-30

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 113.27  E-value: 6.18e-30
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442628159    58 IGQRVWLGGTRPGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSRLTRL 122
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 571-1424 1.74e-27

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 121.70  E-value: 1.74e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   571 LDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEklvrem 650
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEK------ 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   651 tenaINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQA 730
Cdd:TIGR02168  269 ----LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   731 ALEELKKEKETI---IKEKEQELQQLQSKSAESESALkvvqvqleqlqqqaaasgEEGSKTVAKLHDEISQLKSQAEETQ 807
Cdd:TIGR02168  345 KLEELKEELESLeaeLEELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   808 SELKSTQSNLEAKSKQLEAANGSLEEEAKKSghLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEY 887
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   888 AESRA----------EASDLQDKVKE----------ITDTLHAELQAERSSSSALHTKLSKFSDEIATghkelTSKADAW 947
Cdd:TIGR02168  485 AQLQArldslerlqeNLEGFSEGVKAllknqsglsgILGVLSELISVDEGYEAAIEAALGGRLQAVVV-----ENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   948 SQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKE--KSFEESIKNLQEEVTKAKTeNLELSTGTQTTIKDLQERLEIT 1025
Cdd:TIGR02168  560 KAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKniEGFLGVAKDLVKFDPKLRK-ALSYLLGGVLVVDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1026 NaELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELstvlevlqaeksetnhifelfemeadmnsERLIEKVTG 1105
Cdd:TIGR02168  639 K-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREI-----------------------------EELEEKIEE 688

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1106 IKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSS 1185
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEE 768

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1186 IIEAQNTKLNESNVQLENKTSCLKETQDQ-------LLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVK 1258
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEElkalreaLDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1259 VLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1338
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1339 TVLESQKKSHNEIQDKL--------EQAQQKERTLQEETSKLAEQLSQLKQ-----------ANEELQKSLQQKQLLLEK 1399
Cdd:TIGR02168  929 LRLEGLEVRIDNLQERLseeysltlEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaAIEEYEELKERYDFLTAQ 1008

                          890       900
                   ....*....|....*....|....*
gi 442628159  1400 GNEFDTQLAEYQKVIDEMDDAASVK 1424
Cdd:TIGR02168 1009 KEDLTEAKETLEEAIEEIDREARER 1033
NIP100 super family cl34954
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 170-748 3.43e-10

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG5244:

Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 64.71  E-value: 3.43e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  170 MAVGDRVIVSSGFGsrpgILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFV--------------- 234
Cdd:COG5244     4 LSVNDRVLLGDKFG----TVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIrpdddsllngnaaye 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  235 --------------PIAKVSLSPSSKKTRLSRTGSRESLTSIGTMNSIATTATSRMR--------MNAQQRKSSTPVKPI 292
Cdd:COG5244    80 kikgglvceskgmdKDGEIKQENHEDRIHFEESKIRRLEETIEALKSTEKEEIVELRreneeldkINLSLRERISSEEPE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  293 LATPKSQFSMQDL--LREKQQHVEKLMVERDLDREDAQNQALQLQKNI--NELKARIVE--------LESALDNERKKTE 360
Cdd:COG5244   160 LNKDGSKLSYDELkeFVEESRVQVYDMVELVSDISETLNRNGSIQRSSvrECERSNIHDvlflvngiLDGVIDELNGELE 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  361 ELQ---CSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLvsATPSLQSILPPDLPSDDGALQEEIAKLQEKMTIQQkeV 437
Cdd:COG5244   240 RLRrqlVSLMSSHGIEVEENSRLKATLEKFQSLELKVNTL--QEELYQNKLLKKFYQIYEPFAQAALSSQLQYLAEV--I 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  438 ESRIAEQLEeeqrlrenvkylNEQIATLQSELVSKDEALEKFSLSECgiENLRRELELLKEENEKQAQEAQAEFTRKLAE 517
Cdd:COG5244   316 ESENFGKLE------------NIEIHIILKVLSSISYALHIYTIKNT--PDHLETTLQCFVNIAPISMWLSEFLQRKFSS 381

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  518 KSVEVLrlsSELQNLKATSDSLE----------------------SERVNKTDECEILQTEVRMRdeQIRELNQQlDEVT 575
Cdd:COG5244   382 KQETAF---SICQFLEDNKDVTLilkilhpilettvpkllaflrtNSNFNDNDTLCLIGSLYEIA--RIDKLIGK-EEIS 455

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  576 TQLN----VQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMT 651
Cdd:COG5244   456 KQDNrlflYPSCDITLSSILTILFSDKLEVFFQGIESLLENITIFPEQPSQQTSDSENIKENSLLSDRLNEENIRLKEVL 535

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  652 ENAINQIQLEKESieQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHE---KL 728
Cdd:COG5244   536 VQKENMLTEETKI--KIIIGRDLERKTLEENIKTLKVELNNKNNKLKEENFNLVNRLKNMELKLYQIKDNNTLNKiylDL 613

                         650       660
                  ....*....|....*....|
gi 442628159  729 QAALEELKKEKETIIKEKEQ 748
Cdd:COG5244   614 VSEIMELRETIRRQIKEQKR 633
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1601-1617 1.25e-06

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 45.92  E-value: 1.25e-06
                           10
                   ....*....|....*..
gi 442628159  1601 RKYCDSCEVFGHDTSEC 1617
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1554-1571 9.17e-05

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.91  E-value: 9.17e-05
                           10
                   ....*....|....*...
gi 442628159  1554 RLFCDICDEFDqHDTEDC 1571
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
COG4913 super family cl25907
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1362-1531 1.20e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


The actual alignment was detected with superfamily member COG4913:

Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1362 ERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLL---EKGNEFDTQLAEYQkVIDEMDDAASV--KSALLEQLQNRVA 1436
Cdd:COG4913   220 EPDTFEAADALVEHFDDLERAHEALEDAREQIELLEpirELAERYAAARERLA-ELEYLRAALRLwfAQRRLELLEAELE 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1437 ELETALRQANDAQKtayletkELRRQLESLEleksREVLSLKAQMNGASsrsgkGDEVESLDietslAKINFLNSIIADM 1516
Cdd:COG4913   299 ELRAELARLEAELE-------RLEARLDALR----EELDELEAQIRGNG-----GDRLEQLE-----REIERLERELEER 357

                         170
                  ....*....|....*
gi 442628159 1517 QQKNDALKAKVQTLE 1531
Cdd:COG4913   358 ERRRARLEALLAALG 372
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 172-239 9.54e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.44  E-value: 9.54e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442628159   172 VGDRVIVSsgfGSRPGILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFVPIAKV 239
Cdd:pfam01302    1 VGDRVEVP---GGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 58-122 6.18e-30

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 113.27  E-value: 6.18e-30
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442628159    58 IGQRVWLGGTRPGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSRLTRL 122
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 172-240 2.57e-29

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 111.91  E-value: 2.57e-29
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159    172 VGDRVIVSSGfgSRPGILRYLGETQFAPGNWCGVELDEP-SGKNDGTVDDIRYFECKPKYGVFVPIAKVS 240
Cdd:smart01052    1 VGDRVEVGGG--GRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 571-1424 1.74e-27

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 121.70  E-value: 1.74e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   571 LDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEklvrem 650
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEK------ 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   651 tenaINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQA 730
Cdd:TIGR02168  269 ----LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   731 ALEELKKEKETI---IKEKEQELQQLQSKSAESESALkvvqvqleqlqqqaaasgEEGSKTVAKLHDEISQLKSQAEETQ 807
Cdd:TIGR02168  345 KLEELKEELESLeaeLEELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   808 SELKSTQSNLEAKSKQLEAANGSLEEEAKKSghLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEY 887
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   888 AESRA----------EASDLQDKVKE----------ITDTLHAELQAERSSSSALHTKLSKFSDEIATghkelTSKADAW 947
Cdd:TIGR02168  485 AQLQArldslerlqeNLEGFSEGVKAllknqsglsgILGVLSELISVDEGYEAAIEAALGGRLQAVVV-----ENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   948 SQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKE--KSFEESIKNLQEEVTKAKTeNLELSTGTQTTIKDLQERLEIT 1025
Cdd:TIGR02168  560 KAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKniEGFLGVAKDLVKFDPKLRK-ALSYLLGGVLVVDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1026 NaELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELstvlevlqaeksetnhifelfemeadmnsERLIEKVTG 1105
Cdd:TIGR02168  639 K-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREI-----------------------------EELEEKIEE 688

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1106 IKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSS 1185
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEE 768

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1186 IIEAQNTKLNESNVQLENKTSCLKETQDQ-------LLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVK 1258
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEElkalreaLDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1259 VLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1338
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1339 TVLESQKKSHNEIQDKL--------EQAQQKERTLQEETSKLAEQLSQLKQ-----------ANEELQKSLQQKQLLLEK 1399
Cdd:TIGR02168  929 LRLEGLEVRIDNLQERLseeysltlEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaAIEEYEELKERYDFLTAQ 1008

                          890       900
                   ....*....|....*....|....*
gi 442628159  1400 GNEFDTQLAEYQKVIDEMDDAASVK 1424
Cdd:TIGR02168 1009 KEDLTEAKETLEEAIEEIDREARER 1033
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 58-123 3.33e-23

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 94.19  E-value: 3.33e-23
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442628159     58 IGQRVWLGGT-RPGQIAFIGDTHFAAGEWAGVVLDEPN-GKNDGCVSGKRYFQCEPKRGIFSRLTRLT 123
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1101-1452 2.31e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.02  E-value: 2.31e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1101 EKVTGIKEELKETH-----LQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQN 1175
Cdd:COG1196   213 ERYRELKEELKELEaelllLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1176 LEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEE 1255
Cdd:COG1196   293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1256 LVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLD 1335
Cdd:COG1196   373 ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1336 ESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVID 1415
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGV 532

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 442628159 1416 EMDDAASVKSALLEQLQNRVAELETALRQANDAQKTA 1452
Cdd:COG1196   533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAA 569
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
824-1446 3.04e-17

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 88.17  E-value: 3.04e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  824 LEAANGSLEE-----EAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEkvnkEYAESRAEASDLQ 898
Cdd:PRK02224  182 LSDQRGSLDQlkaqiEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLE----EHEERREELETLE 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  899 DKVKEITDTLhAELQAERSS-SSALHTK---LSKFSDEIA-----TGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQ 969
Cdd:PRK02224  258 AEIEDLRETI-AETEREREElAEEVRDLrerLEELEEERDdllaeAGLDDADAEAVEARREELEDRDEELRDRLEECRVA 336

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  970 DSQTKLKAEGERkeksfeESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEitnaelqhkekmasedaqKIADLKTL 1049
Cdd:PRK02224  337 AQAHNEEAESLR------EDADDLEERAEELREEAAELESELEEAREAVEDRRE------------------EIEELEEE 392

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1050 VEAIQVANANISATNAELSTVLEVLQAEKSETNHifELFEMEADMNSER-LIEKVTGIKEELK----------ETHLQ-L 1117
Cdd:PRK02224  393 IEELRERFGDAPVDLGNAEDFLEELREERDELRE--REAELEATLRTAReRVEEAEALLEAGKcpecgqpvegSPHVEtI 470

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1118 DERQKKFEELEEKLKQAQqseqklqqESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNEs 1197
Cdd:PRK02224  471 EEDRERVEELEAELEDLE--------EEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEE- 541

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1198 nvqlenktsclketqdqllesqkkekqLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQAt 1277
Cdd:PRK02224  542 ---------------------------LRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLER- 593

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1278 nkeLQELLVKSQENEGNLQgeslAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDEsntvlesqkkshneiqDKLEQ 1357
Cdd:PRK02224  594 ---IRTLLAAIADAEDEIE----RLREKREALAELNDERRERLAEKRERKRELEAEFDE----------------ARIEE 650

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1358 AQQKERTLQEETSKLAEQLSQLKQANEELQKSLqqkqlllekgNEFDTQLAEYQKVIDEMDDAASVKSAL------LEQL 1431
Cdd:PRK02224  651 AREDKERAEEYLEQVEEKLDELREERDDLQAEI----------GAVENELEELEELRERREALENRVEALealydeAEEL 720

                         650
                  ....*....|....*
gi 442628159 1432 QNRVAELETALRQAN 1446
Cdd:PRK02224  721 ESMYGDLRAELRQRN 735
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 600-1402 1.12e-16

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 86.56  E-value: 1.12e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   600 EEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLA--EQEKLVREMTENAINQIQLEKESIEQQLALKQNELE 677
Cdd:pfam02463  186 AELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLylDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   678 DFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKeketiikeKEQELQQLQSKS 757
Cdd:pfam02463  266 KLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK--------AEKELKKEKEEI 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   758 AESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKK 837
Cdd:pfam02463  338 EELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQL 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   838 SGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERS 917
Cdd:pfam02463  418 EDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEE 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   918 SSSAL--HTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLqe 995
Cdd:pfam02463  498 RSQKEskARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPL-- 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   996 evTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQ 1075
Cdd:pfam02463  576 --GARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVS 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1076 AEKSETNHIFELFEMEaDMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEI 1155
Cdd:pfam02463  654 LEEGLAEKSEVKASLS-ELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQD 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1156 QQSlQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQlQEEAAKLSGE 1235
Cdd:pfam02463  733 KIN-EELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQE-EELRALEEEL 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1236 LQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGE 1315
Cdd:pfam02463  811 KEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELES 890

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1316 LKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQL 1395
Cdd:pfam02463  891 KEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKE 970


                   ....*..
gi 442628159  1396 LLEKGNE 1402
Cdd:pfam02463  971 ELGKVNL 977
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 170-748 3.43e-10

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 64.71  E-value: 3.43e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  170 MAVGDRVIVSSGFGsrpgILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFV--------------- 234
Cdd:COG5244     4 LSVNDRVLLGDKFG----TVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIrpdddsllngnaaye 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  235 --------------PIAKVSLSPSSKKTRLSRTGSRESLTSIGTMNSIATTATSRMR--------MNAQQRKSSTPVKPI 292
Cdd:COG5244    80 kikgglvceskgmdKDGEIKQENHEDRIHFEESKIRRLEETIEALKSTEKEEIVELRreneeldkINLSLRERISSEEPE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  293 LATPKSQFSMQDL--LREKQQHVEKLMVERDLDREDAQNQALQLQKNI--NELKARIVE--------LESALDNERKKTE 360
Cdd:COG5244   160 LNKDGSKLSYDELkeFVEESRVQVYDMVELVSDISETLNRNGSIQRSSvrECERSNIHDvlflvngiLDGVIDELNGELE 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  361 ELQ---CSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLvsATPSLQSILPPDLPSDDGALQEEIAKLQEKMTIQQkeV 437
Cdd:COG5244   240 RLRrqlVSLMSSHGIEVEENSRLKATLEKFQSLELKVNTL--QEELYQNKLLKKFYQIYEPFAQAALSSQLQYLAEV--I 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  438 ESRIAEQLEeeqrlrenvkylNEQIATLQSELVSKDEALEKFSLSECgiENLRRELELLKEENEKQAQEAQAEFTRKLAE 517
Cdd:COG5244   316 ESENFGKLE------------NIEIHIILKVLSSISYALHIYTIKNT--PDHLETTLQCFVNIAPISMWLSEFLQRKFSS 381

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  518 KSVEVLrlsSELQNLKATSDSLE----------------------SERVNKTDECEILQTEVRMRdeQIRELNQQlDEVT 575
Cdd:COG5244   382 KQETAF---SICQFLEDNKDVTLilkilhpilettvpkllaflrtNSNFNDNDTLCLIGSLYEIA--RIDKLIGK-EEIS 455

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  576 TQLN----VQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMT 651
Cdd:COG5244   456 KQDNrlflYPSCDITLSSILTILFSDKLEVFFQGIESLLENITIFPEQPSQQTSDSENIKENSLLSDRLNEENIRLKEVL 535

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  652 ENAINQIQLEKESieQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHE---KL 728
Cdd:COG5244   536 VQKENMLTEETKI--KIIIGRDLERKTLEENIKTLKVELNNKNNKLKEENFNLVNRLKNMELKLYQIKDNNTLNKiylDL 613

                         650       660
                  ....*....|....*....|
gi 442628159  729 QAALEELKKEKETIIKEKEQ 748
Cdd:COG5244   614 VSEIMELRETIRRQIKEQKR 633
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 58-118 4.32e-08

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 58.16  E-value: 4.32e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 442628159   58 IGQRVWLGGTRpGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSR 118
Cdd:COG5244     6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIR 65
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 420-703 1.07e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 53.59  E-value: 1.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   420 QEEIAKLQEKMTIQQKevesRIAEQLEEEQRLRENVKYLNEQIATLqselVSKDEALEKFSLSECGIENLRRELELLKEE 499
Cdd:pfam17380  332 QAAIYAEQERMAMERE----RELERIRQEERKRELERIRQEEIAME----ISRMRELERLQMERQQKNERVRQELEAARK 403

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   500 NEKQAQEAQaeftRKLAEKSVEVLRLSSELQNLKATS-DSLESERVNktdECEILQTEVRMRDEQIRELNQQLDEvttql 578
Cdd:pfam17380  404 VKILEEERQ----RKIQQQKVEMEQIRAEQEEARQREvRRLEEERAR---EMERVRLEEQERQQQVERLRQQEEE----- 471

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   579 nvQKADSSALDDMLRLQKEGTEEKSTLLEKtekELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQI 658
Cdd:pfam17380  472 --RKRKKLELEKEKRDRKRAEEQRRKILEK---ELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQ 546

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 442628159   659 QL-EKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFE 703
Cdd:pfam17380  547 EMeERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYE 592
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1601-1617 1.25e-06

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 45.92  E-value: 1.25e-06
                           10
                   ....*....|....*..
gi 442628159  1601 RKYCDSCEVFGHDTSEC 1617
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
PRK11281 PRK11281
mechanosensitive channel MscK;
347-757 9.30e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 50.68  E-value: 9.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  347 ELESALD--NERKKTEE----LQCSIDEAQfcgdELNAQSQVYKEKIHDLESKITKlvsATPSLQSIlppdlpsddgalQ 420
Cdd:PRK11281   40 DVQAQLDalNKQKLLEAedklVQQDLEQTL----ALLDKIDRQKEETEQLKQQLAQ---APAKLRQA------------Q 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  421 EEIAKLQEKM---------TIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSelvskdealekfslsecgienlrr 491
Cdd:PRK11281  101 AELEALKDDNdeetretlsTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQT------------------------ 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  492 elellkeenekQAQEAQAEftrkLAEKSVEVLRLSSELQNLKATSDSLESERVNKtdeceiLQTEVRMRDEQIrELNQQL 571
Cdd:PRK11281  157 -----------QPERAQAA----LYANSQRLQQIRNLLKGGKVGGKALRPSQRVL------LQAEQALLNAQN-DLQRKS 214

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  572 DEVTTQLNvqkadssaldDMLRLQKEGTEEKSTLLEKT---------EKELVQSKEQAAKTLNDKE------------QL 630
Cdd:PRK11281  215 LEGNTQLQ----------DLLQKQRDYLTARIQRLEHQlqllqeainSKRLTLSEKTVQEAQSQDEaariqanplvaqEL 284

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  631 E--KQISD--------LKQLAEQEKLVREMTENAINQIQLEKESI--------------EQQLALKQNEL-EDFQKKQSE 685
Cdd:PRK11281  285 EinLQLSQrllkatekLNTLTQQNLRVKNWLDRLTQSERNIKEQIsvlkgslllsrilyQQQQALPSADLiEGLADRIAD 364

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  686 SEVHLQEIkaqNTQKDfELVESGESLKKLQQQleQKTLGHEKLQAALEELKKEKETIIKEKEQEL--------------Q 751
Cdd:PRK11281  365 LRLEQFEI---NQQRD-ALFQPDAYIDKLEAG--HKSEVTDEVRDALLQLLDERRELLDQLNKQLnnqlnlainlqlnqQ 438


                  ....*.
gi 442628159  752 QLQSKS 757
Cdd:PRK11281  439 QLLSVS 444
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1554-1571 9.17e-05

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.91  E-value: 9.17e-05
                           10
                   ....*....|....*...
gi 442628159  1554 RLFCDICDEFDqHDTEDC 1571
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1362-1531 1.20e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1362 ERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLL---EKGNEFDTQLAEYQkVIDEMDDAASV--KSALLEQLQNRVA 1436
Cdd:COG4913   220 EPDTFEAADALVEHFDDLERAHEALEDAREQIELLEpirELAERYAAARERLA-ELEYLRAALRLwfAQRRLELLEAELE 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1437 ELETALRQANDAQKtayletkELRRQLESLEleksREVLSLKAQMNGASsrsgkGDEVESLDietslAKINFLNSIIADM 1516
Cdd:COG4913   299 ELRAELARLEAELE-------RLEARLDALR----EELDELEAQIRGNG-----GDRLEQLE-----REIERLERELEER 357

                         170
                  ....*....|....*
gi 442628159 1517 QQKNDALKAKVQTLE 1531
Cdd:COG4913   358 ERRRARLEALLAALG 372
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 564-944 1.73e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 43.08  E-value: 1.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  564 IRELNQQLDEVTTQLNVqkadsSALDDMLRLQKEGTEEKSTLLEKTEKELvqSKEQAAKTLNDKEQLEKQISDL-KQLAE 642
Cdd:NF033838   71 LSEIQKSLDKRKHTQNV-----ALNKKLSDIKTEYLYELNVLKEKSEAEL--TSKTKKELDAAFEQFKKDTLEPgKKVAE 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  643 QEKLVREMTENAINQIQlEKESIEQQLALKQNELE--DFQKKQSESEVHLQEIKAQNTQKDfelvesgESLKKLQQQLEQ 720
Cdd:NF033838  144 ATKKVEEAEKKAKDQKE-EDRRNYPTNTYKTLELEiaESDVEVKKAELELVKEEAKEPRDE-------EKIKQAKAKVES 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  721 KtlgheklQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLK 800
Cdd:NF033838  216 K-------KAEATRLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKRGVLGEPATPDKKENDAKSSDS 288

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  801 SQAEET--QSELKSTQSNLEAKSKQLEAangslEEEAKksghlleqitKLKSEVGETQAALSSCHTDVESKTKQLEAANA 878
Cdd:NF033838  289 SVGEETlpSPSLKPEKKVAEAEKKVEEA-----KKKAK----------DQKEEDRRNYPTNTYKTLELEIAESDVKVKEA 353

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 442628159  879 ALEKVNKEYAESRAEasdlqDKVKEItdtlhaelQAERSSSSALHTKLSKFSDEIATGHKELTSKA 944
Cdd:NF033838  354 ELELVKEEAKEPRNE-----EKIKQA--------KAKVESKKAEATRLEKIKTDRKKAEEEAKRKA 406
ClyA-like cd21116
family of the cytolysin A (ClyA) family alpha pore-forming toxins (alpha-PFT) including ...
 1130-1278 2.96e-03

family of the cytolysin A (ClyA) family alpha pore-forming toxins (alpha-PFT) including Bacillus cereus HblB, Aeromonas hydrophila AhlB, Bacillus thuringiensis Cry6Aa and similar proteins; This family belongs to the ClyA family of alpha-PFT bacterial toxins. PFTs form the major group of virulence factors in many pathogenic bacteria and in general are critical components of the molecular offensive and defensive machinery of cells in all kingdoms of life. Bacterial PFTs facilitate the takeover of host resources by puncturing holes in the membrane. PFTs can be classified as alpha-PFTs and beta-PFTs depending on the secondary structures of their membrane component. Alpha-PFTs use a ring of amphipathic helices while beta-PFTs use a beta-barrel to construct the pore. Members of this family include the toxins: Bacillus cereus hemolysin binding component B (HblB or HBL-B) of the diarrheal enterotoxin hemolysin BL, Aeromonas hydrophila hemolytic (Ahl) component B (AhlB) of the tripartite AhlABC toxin, Vibrio cholerae cytotoxin motility associated killing factor A (MakA) cytotoxin, Xenorhabdus nematophila alpha-xenorhabdolysin (XaxA), Bacillus thuringiensis crystal 6Aa (Cry6Aa) parasporal crystal (Cry) toxin, and Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA) of the non-hemolytic enterotoxin Nhe, which, despite its name, is hemolytic, among others. In solution, ClyA proteins have an elongated, almost entirely alpha-helical structure, except for a short hydrophobic beta-hairpin known as the beta-tongue. Pore formation by ClyA requires circular oligomerization of the toxin by a sequential mechanism. This, in turn, concentrates the amphipathic helices in the center of the ring-like structure, forming a helical barrel that inserts into the membrane by a wedge-like mechanism. Compared with ClyA, NheA is almost entirely alpha-helical with an enlarged "head" domain, and an enlarged beta-tongue; it has been proposed that NheA could even form beta-barrel pores. Alpha-PFTs with similar structures are increasingly being found in eukaryotes, in particular as components of the immune systems of animals. This family may be distantly related to Escherichia coli alpha-PFT hemolysin E (HlyE, also known as ClyA or SheA).


Pssm-ID: 439149 [Multi-domain]  Cd Length: 224  Bit Score: 40.86  E-value: 2.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1130 KLKQAQQSEQKLQQESQTSKEKLteiQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLK 1209
Cdd:cd21116    74 YYPDLIELADNLIKGDQGAKQQL---LQGLEALQSQVTKKQTSVTSFINELTTFKNDLDDDSRNLQTDATKAQAQVAVLN 150

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 442628159 1210 ETQDQLlesqkkeKQLQEEAAKLSGELQQVQEANGDIKDSLvkveelvKVLEEKLQAATSQLDAQQATN 1278
Cdd:cd21116   151 ALKNQL-------NSLAEQIDAAIDALEKLSNDWQTLDSDI-------KELITDLEDAESSIDAAFLQA 205
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1154-1381 5.75e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 40.77  E-value: 5.75e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   1154 EIQQ-SLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQlLESQK-----KEKQLQE 1227
Cdd:smart00787   66 ELYQfSCKELKKYISEGRDLFKEIEEETLINNPPLFKEYFSASPDVKLLMDKQFQLVKTFAR-LEAKKmwyewRMKLLEG 144

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   1228 EAAKLSGELQQVQEAngdiKDSLVKVEELVKVLEEKLQaatsqlDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQ 1307
Cdd:smart00787  145 LKEGLDENLEGLKED----YKLLMKELELLNSIKPKLR------DRKDALEEELRQLKQLEDELEDCDPTELDRAKEKLK 214

                           170       180       190       200       210       220       230
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 442628159   1308 QLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTlqeETSKLAEQLSQLKQ 1381
Cdd:smart00787  215 KLLQEIMIKVKKLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQCRGFTFK---EIEKLKEQLKLLQS 285
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 172-239 9.54e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.44  E-value: 9.54e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442628159   172 VGDRVIVSsgfGSRPGILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFVPIAKV 239
Cdd:pfam01302    1 VGDRVEVP---GGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 58-122 6.18e-30

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 113.27  E-value: 6.18e-30
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442628159    58 IGQRVWLGGTRPGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSRLTRL 122
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 172-240 2.57e-29

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 111.91  E-value: 2.57e-29
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159    172 VGDRVIVSSGfgSRPGILRYLGETQFAPGNWCGVELDEP-SGKNDGTVDDIRYFECKPKYGVFVPIAKVS 240
Cdd:smart01052    1 VGDRVEVGGG--GRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 571-1424 1.74e-27

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 121.70  E-value: 1.74e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   571 LDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEklvrem 650
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEK------ 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   651 tenaINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQA 730
Cdd:TIGR02168  269 ----LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   731 ALEELKKEKETI---IKEKEQELQQLQSKSAESESALkvvqvqleqlqqqaaasgEEGSKTVAKLHDEISQLKSQAEETQ 807
Cdd:TIGR02168  345 KLEELKEELESLeaeLEELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   808 SELKSTQSNLEAKSKQLEAANGSLEEEAKKSghLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEY 887
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   888 AESRA----------EASDLQDKVKE----------ITDTLHAELQAERSSSSALHTKLSKFSDEIATghkelTSKADAW 947
Cdd:TIGR02168  485 AQLQArldslerlqeNLEGFSEGVKAllknqsglsgILGVLSELISVDEGYEAAIEAALGGRLQAVVV-----ENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   948 SQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKE--KSFEESIKNLQEEVTKAKTeNLELSTGTQTTIKDLQERLEIT 1025
Cdd:TIGR02168  560 KAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKniEGFLGVAKDLVKFDPKLRK-ALSYLLGGVLVVDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1026 NaELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELstvlevlqaeksetnhifelfemeadmnsERLIEKVTG 1105
Cdd:TIGR02168  639 K-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREI-----------------------------EELEEKIEE 688

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1106 IKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSS 1185
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEE 768

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1186 IIEAQNTKLNESNVQLENKTSCLKETQDQ-------LLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVK 1258
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEElkalreaLDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1259 VLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1338
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1339 TVLESQKKSHNEIQDKL--------EQAQQKERTLQEETSKLAEQLSQLKQ-----------ANEELQKSLQQKQLLLEK 1399
Cdd:TIGR02168  929 LRLEGLEVRIDNLQERLseeysltlEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaAIEEYEELKERYDFLTAQ 1008

                          890       900
                   ....*....|....*....|....*
gi 442628159  1400 GNEFDTQLAEYQKVIDEMDDAASVK 1424
Cdd:TIGR02168 1009 KEDLTEAKETLEEAIEEIDREARER 1033
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 562-1363 3.49e-24

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 110.93  E-value: 3.49e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   562 EQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKE----QLEKQISDL 637
Cdd:TIGR02169  184 ENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEeeleKLTEEISEL 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   638 KQ--------LAEQEKLVREMTENAINQIQ-------LEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQntqkdf 702
Cdd:TIGR02169  264 EKrleeieqlLEELNKKIKDLGEEEQLRVKekigeleAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAE------ 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   703 elvesgesLKKLQQQLEQKTLGHEKLQAALEELKKEKETIikekEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASG 782
Cdd:TIGR02169  338 --------IEELEREIEEERKRRDKLTEEYAELKEELEDL----RAELEEVDKEFAETRDELKDYREKLEKLKREINELK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   783 EEGSK---TVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAAL 859
Cdd:TIGR02169  406 RELDRlqeELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKEL 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   860 SSchtdvesKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALhtklskfsdEIATGH-- 937
Cdd:TIGR02169  486 SK-------LQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAI---------EVAAGNrl 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   938 KELTSKADAWSQEMLQKEKELQELRQ------QLQDSQDSQTKLKAEG------------ERKEKSFE---------ESI 990
Cdd:TIGR02169  550 NNVVVEDDAVAKEAIELLKRRKAGRAtflplnKMRDERRDLSILSEDGvigfavdlvefdPKYEPAFKyvfgdtlvvEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   991 KNLQEEVTKAKTENLE---------------LSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQV 1055
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEgelfeksgamtggsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1056 ANANISATNAELSTVLEVLQAEKSETNHIFElfEMEADMNSerLIEKVTGIKEELKETHLQLDERQKKFEELEEKL---- 1131
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLE--ELEEDLSS--LEQEIENVKSELKELEARIEELEEDLHKLEEALndle 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1132 --------KQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLEN 1203
Cdd:TIGR02169  786 arlshsriPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEE 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1204 KTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQE 1283
Cdd:TIGR02169  866 LEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEE 945

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1284 lLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDesntVLESQKKshnEIQDKLEQAQQKER 1363
Cdd:TIGR02169  946 -IPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRA----KLEEERK---AILERIEEYEKKKR 1017
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 58-123 3.33e-23

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 94.19  E-value: 3.33e-23
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442628159     58 IGQRVWLGGT-RPGQIAFIGDTHFAAGEWAGVVLDEPN-GKNDGCVSGKRYFQCEPKRGIFSRLTRLT 123
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 681-1442 1.13e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 105.91  E-value: 1.13e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   681 KKQSESEVHLQEIKAQNTQKDFELveSGESLKKLQQQLEQKtlghEKLQAALEELKKEKETIIKEKEQELQQLQSKSAES 760
Cdd:TIGR02168  206 ERQAEKAERYKELKAELRELELAL--LVLRLEELREELEEL----QEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   761 ESALKVVQVQLEQLqqqaaasgeegSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGH 840
Cdd:TIGR02168  280 EEEIEELQKELYAL-----------ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   841 LLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSS 920
Cdd:TIGR02168  349 LKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   921 ALH-TKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKE--KSFEESIKNLQEEV 997
Cdd:TIGR02168  429 KLEeAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDslERLQENLEGFSEGV 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   998 TKAKTENLELSTGTQTtikdLQERLEITNAELQHKEKMASEDAQKIadlktLVEAIQVANANISA---TNAELSTVLE-- 1072
Cdd:TIGR02168  509 KALLKNQSGLSGILGV----LSELISVDEGYEAAIEAALGGRLQAV-----VVENLNAAKKAIAFlkqNELGRVTFLPld 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1073 VLQAEKSETNHIFELFEMEADMNSERLIEK------------------VTGIKEEL------------------------ 1110
Cdd:TIGR02168  580 SIKGTEIQGNDREILKNIEGFLGVAKDLVKfdpklrkalsyllggvlvVDDLDNALelakklrpgyrivtldgdlvrpgg 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1111 ------KETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESS 1184
Cdd:TIGR02168  660 vitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE 739

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1185 SIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKL 1264
Cdd:TIGR02168  740 AEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEA 819

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1265 QAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEAlcqkengLKELQGKLDESNTVLESQ 1344
Cdd:TIGR02168  820 ANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE-------LEALLNERASLEEALALL 892

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1345 KKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQkqlLLEKGNEfdtqlaEYQKVIDEMDDAASVK 1424
Cdd:TIGR02168  893 RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN---LQERLSE------EYSLTLEEAEALENKI 963

                          810
                   ....*....|....*...
gi 442628159  1425 SALLEQLQNRVAELETAL 1442
Cdd:TIGR02168  964 EDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1101-1452 2.31e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.02  E-value: 2.31e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1101 EKVTGIKEELKETH-----LQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQN 1175
Cdd:COG1196   213 ERYRELKEELKELEaelllLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1176 LEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEE 1255
Cdd:COG1196   293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1256 LVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLD 1335
Cdd:COG1196   373 ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1336 ESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVID 1415
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGV 532

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 442628159 1416 EMDDAASVKSALLEQLQNRVAELETALRQANDAQKTA 1452
Cdd:COG1196   533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAA 569
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 433-1392 3.48e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 104.37  E-value: 3.48e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   433 QQKEVESRIAEQLEEEQRLRENVKYLNEQIATL--QSELVSK----DEALEKFSLSECGIE-NLRRELELLKEENEKQAQ 505
Cdd:TIGR02168  173 RRKETERKLERTRENLDRLEDILNELERQLKSLerQAEKAERykelKAELRELELALLVLRlEELREELEELQEELKEAE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   506 EAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKAds 585
Cdd:TIGR02168  253 EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES-- 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   586 salddMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKlvremteNAINQIQLEKESI 665
Cdd:TIGR02168  331 -----KLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR-------SKVAQLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   666 eqqlalkQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESgeSLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKE 745
Cdd:TIGR02168  399 -------NNEIERLEARLERLEDRRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEALEELREE 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   746 KEQELQQLQsksaesesalkvvqvqleqlqqqaaasgeegsktvaklhdeisQLKSQAEETQSELKSTQSNLEAKSKQLE 825
Cdd:TIGR02168  470 LEEAEQALD-------------------------------------------AAERELAQLQARLDSLERLQENLEGFSE 506

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   826 AANGSLEEEAKKSGHLLEQITKLKSEVGETQA---ALSSCHTDVESKTkqLEAANAALekvnkeyaESRAEASDLQDKVK 902
Cdd:TIGR02168  507 GVKALLKNQSGLSGILGVLSELISVDEGYEAAieaALGGRLQAVVVEN--LNAAKKAI--------AFLKQNELGRVTFL 576

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   903 EITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEkELQElrqqlqdsqdsqtklkAEGERK 982
Cdd:TIGR02168  577 PLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVD-DLDN----------------ALELAK 639

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   983 EKSFEESIKNLQEE-------VTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQV 1055
Cdd:TIGR02168  640 KLRPGYRIVTLDGDlvrpggvITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRK 719

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1056 ANANISATNAELSTVLEVLQAEksetnhifelfemeadmnSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQ 1135
Cdd:TIGR02168  720 ELEELSRQISALRKDLARLEAE------------------VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE 781

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1136 QSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQL 1215
Cdd:TIGR02168  782 AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1216 LESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNL 1295
Cdd:TIGR02168  862 EELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1296 QG---ESLAVTEKLQQLEQANGELKEALCQKEngLKELQGKLDESNTV-------LESQKKSHNEIQDKLEQAQQKERTL 1365
Cdd:TIGR02168  942 QErlsEEYSLTLEEAEALENKIEDDEEEARRR--LKRLENKIKELGPVnlaaieeYEELKERYDFLTAQKEDLTEAKETL 1019

                          970       980
                   ....*....|....*....|....*...
gi 442628159  1366 QEETSKL-AEQLSQLKQANEELQKSLQQ 1392
Cdd:TIGR02168 1020 EEAIEEIdREARERFKDTFDQVNENFQR 1047
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 628-1475 7.99e-22

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 103.22  E-value: 7.99e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   628 EQLEKQISDLKQLAEQEKLVREMTENAINQiqLEKESIEQQLALKQNELEDfQKKQSESEVHLQEIKAQNTQK---DFEL 704
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQ--LERLRREREKAERYQALLK-EKREYEGYELLKEKEALERQKeaiERQL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   705 VESGESLKKLQQQLEQKTLGHEKLQAALEELKKEketIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEE 784
Cdd:TIGR02169  247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKK---IKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   785 GSKTVAKLHD---EISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLL-------EQITKLKSEVGE 854
Cdd:TIGR02169  324 LAKLEAEIDKllaEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRdelkdyrEKLEKLKREINE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   855 TQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEIT---DTLHAELQAERSSSSALHTKLSKFSD 931
Cdd:TIGR02169  404 LKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEwklEQLAADLSKYEQELYDLKEEYDRVEK 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   932 EIATGHKELTSK---ADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKN-LQ------EEVTKAK 1001
Cdd:TIGR02169  484 ELSKLQRELAEAeaqARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNrLNnvvvedDAVAKEA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1002 TENLELSTGTQTTIkdlqerLEITNAELQHKEKMASEDAQKIADLKTLVE-AIQVANANISATNAELstVLEVLQAEKsE 1080
Cdd:TIGR02169  564 IELLKRRKAGRATF------LPLNKMRDERRDLSILSEDGVIGFAVDLVEfDPKYEPAFKYVFGDTL--VVEDIEAAR-R 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1081 TNHIFELFEMEADmnserLIEK---VTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQ 1157
Cdd:TIGR02169  635 LMGKYRMVTLEGE-----LFEKsgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1158 SLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGEL- 1236
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLs 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1237 -QQVQEangdIKDSLVKVEELVKVLEEKLQaatsqlDAQQATNKELQELLVKSQENEgNLQGESLAVTEKLQQLEQANGE 1315
Cdd:TIGR02169  790 hSRIPE----IQAELSKLEEEVSRIEARLR------EIEQKLNRLTLEKEYLEKEIQ-ELQEQRIDLKEQIKSIEKEIEN 858

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1316 LKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKslqqkql 1395
Cdd:TIGR02169  859 LNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEE------- 931

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1396 llekgnefdtQLAEYQKVIDEMDDaASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLesLELEKSREVL 1475
Cdd:TIGR02169  932 ----------ELSEIEDPKGEDEE-IPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRL--DELKEKRAKL 998
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 306-1023 8.64e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 99.75  E-value: 8.64e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   306 LREKQQHVEKL-MVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQfcgDELNAQSQvyk 384
Cdd:TIGR02168  222 LRELELALLVLrLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQ---KELYALAN--- 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   385 eKIHDLESKITKLVSATPSLQsilppdlpSDDGALQEEIAKLQEKMTIQQKE---VESRIAEQLEEEQRLRENVKYLNEQ 461
Cdd:TIGR02168  296 -EISRLEQQKQILRERLANLE--------RQLEELEAQLEELESKLDELAEElaeLEEKLEELKEELESLEAELEELEAE 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   462 IATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSS-ELQNLKATSDSLE 540
Cdd:TIGR02168  367 LEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEaELKELQAELEELE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   541 SERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEK--------- 611
Cdd:TIGR02168  447 EELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGlsgilgvls 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   612 ELVQSKEQAAKTL-------------NDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELED 678
Cdd:TIGR02168  527 ELISVDEGYEAAIeaalggrlqavvvENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKD 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   679 FQKKQSESEVHLQEI-----------KAQNTQK-----------DFELVESG------------------ESLKKLQQQL 718
Cdd:TIGR02168  607 LVKFDPKLRKALSYLlggvlvvddldNALELAKklrpgyrivtlDGDLVRPGgvitggsaktnssilerrREIEELEEKI 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   719 EQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESeSALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQ 798
Cdd:TIGR02168  687 EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQI-SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   799 LKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANA 878
Cdd:TIGR02168  766 LEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEE 845

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   879 ALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSdeiatghkELTSKADAWSQEMLQKEKEL 958
Cdd:TIGR02168  846 QIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELE--------ELSEELRELESKRSELRREL 917

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442628159   959 QELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLE 1023
Cdd:TIGR02168  918 EELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 796-1439 2.02e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 98.47  E-value: 2.02e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  796 ISQLKSQAEETQSELKSTQSNLE-------AKSKQLEaangSLEEEAKKsghlLEQITKLKSEVGETQAALS-----SCH 863
Cdd:COG1196   167 ISKYKERKEEAERKLEATEENLErledilgELERQLE----PLERQAEK----AERYRELKEELKELEAELLllklrELE 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  864 TDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALhtklskfsDEIATGHKELTSK 943
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAEL--------ARLEQDIARLEER 310

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  944 ADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLE 1023
Cdd:COG1196   311 RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1024 ITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSEtnhifELFEMEADMNSERLIEKV 1103
Cdd:COG1196   391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA-----AEEEAELEEEEEALLELL 465

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1104 TGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVkqkEELVQNLEEKVRES 1183
Cdd:COG1196   466 AELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAV---LIGVEAAYEAALEA 542

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1184 SSIIEAQNtKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEK 1263
Cdd:COG1196   543 ALAAALQN-IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1264 LQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDEsntvles 1343
Cdd:COG1196   622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELE------- 694

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1344 qkkshnEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEkgnEFDTQLAEYQKVIDEMDDAASV 1423
Cdd:COG1196   695 ------LEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE---EEELLEEEALEELPEPPDLEEL 765

                         650
                  ....*....|....*.
gi 442628159 1424 KSAlLEQLQNRVAELE 1439
Cdd:COG1196   766 ERE-LERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 563-1143 5.28e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 97.31  E-value: 5.28e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  563 QIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAE 642
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  643 QEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKT 722
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  723 LGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQ 802
Cdd:COG1196   393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  803 AEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVEskTKQLEAANAALEK 882
Cdd:COG1196   473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE--AALEAALAAALQN 550

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  883 VNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQkekELQELR 962
Cdd:COG1196   551 IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT---LLGRTL 627

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  963 QQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVT-KAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQ 1041
Cdd:COG1196   628 VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTgGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1042 KIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKEthL------ 1115
Cdd:COG1196   708 ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA--Lgpvnll 785

                         570       580       590
                  ....*....|....*....|....*....|.
gi 442628159 1116 ---QLDERQKKFEELEEKLKQAQQSEQKLQQ 1143
Cdd:COG1196   786 aieEYEELEERYDFLSEQREDLEEARETLEE 816
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 324-1162 8.95e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.66  E-value: 8.95e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   324 REDAQNQALQLQKNINELKARIVELESALDN---------------ERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIH 388
Cdd:TIGR02168  174 RKETERKLERTRENLDRLEDILNELERQLKSlerqaekaerykelkAELRELELALLVLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   389 DLESKITKLVSATPSLQsilppDLPSDDGALQEEIAKLQEKM---TIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATL 465
Cdd:TIGR02168  254 ELEELTAELQELEEKLE-----ELRLEVSELEEEIEELQKELyalANEISRLEQQKQILRERLANLERQLEELEAQLEEL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   466 QSelvSKDEALEKFSLSECGIEnLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVN 545
Cdd:TIGR02168  329 ES---KLDELAEELAELEEKLE-ELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   546 KTDECEILQTEVRMRDEQIRELNQQLDEvtTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLN 625
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLEE--AELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   626 DKEQLEKQISDLKQLAEQEklvrEMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQE------------- 692
Cdd:TIGR02168  483 ELAQLQARLDSLERLQENL----EGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGrlqavvvenlnaa 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   693 IKAQNTQKDFE------LVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKE------------TIIKEKEQELQQLQ 754
Cdd:TIGR02168  559 KKAIAFLKQNElgrvtfLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggVLVVDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   755 SKSAESESALKVVQVQLEQLQQQAAASGEEGSKTV------AKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAAN 828
Cdd:TIGR02168  639 KKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLR 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   829 GSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDtl 908
Cdd:TIGR02168  719 KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE-- 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   909 haELQAERSSSSALHTKLSKFSDEIAtghkELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEE 988
Cdd:TIGR02168  797 --ELKALREALDELRAELTLLNEEAA----NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   989 SIKNLqEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISAT-NAEL 1067
Cdd:TIGR02168  871 LESEL-EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlSEEY 949

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1068 STVLEVLQAEKSETnhifELFEMEADMNSERLIEKVTGIK-------EELKETHLQLDERQKKFEELEEKLKQAQQSEQK 1140
Cdd:TIGR02168  950 SLTLEEAEALENKI----EDDEEEARRRLKRLENKIKELGpvnlaaiEEYEELKERYDFLTAQKEDLTEAKETLEEAIEE 1025

                          890       900
                   ....*....|....*....|...
gi 442628159  1141 LQQE-SQTSKEKLTEIQQSLQEL 1162
Cdd:TIGR02168 1026 IDREaRERFKDTFDQVNENFQRV 1048
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1125-1449 7.93e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 93.46  E-value: 7.93e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1125 EELEEKLKQ-AQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVREsssiIEAQNTKLNESNVQLEN 1203
Cdd:COG1196   196 GELERQLEPlERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAE----LEELEAELAELEAELEE 271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1204 KTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQE 1283
Cdd:COG1196   272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1284 LLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKER 1363
Cdd:COG1196   352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1364 TLQEETSKLAEQLSQLKQANEELQ-KSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETAL 1442
Cdd:COG1196   432 ELEEEEEEEEEALEEAAEEEAELEeEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511


                  ....*..
gi 442628159 1443 RQANDAQ 1449
Cdd:COG1196   512 AALLLAG 518
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 303-962 2.18e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 2.18e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   303 QDLLREKQQHVEKLmverdldrEDAQNQALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQFCGDELNAQSQV 382
Cdd:TIGR02168  298 SRLEQQKQILRERL--------ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEE 369

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   383 YKEKIHDLESKITKLVSATPSLQSILppdlpsddGALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENvkylneQI 462
Cdd:TIGR02168  370 LESRLEELEEQLETLRSKVAQLELQI--------ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA------EL 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   463 ATLQSELVSKDEALEKfslsecgienlrrelellKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESE 542
Cdd:TIGR02168  436 KELQAELEELEEELEE------------------LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERL 497

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   543 RVNKtdecEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDML--RLQK------------------------ 596
Cdd:TIGR02168  498 QENL----EGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALggRLQAvvvenlnaakkaiaflkqnelgrv 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   597 ---EGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEK----------- 662
Cdd:TIGR02168  574 tflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRpgyrivtldgd 653

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   663 ------------ESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQA 730
Cdd:TIGR02168  654 lvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRK 733

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   731 ALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEgSKTVAKLHDEISQLKSQAEETQSEL 810
Cdd:TIGR02168  734 DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL-EAQIEQLKEELKALREALDELRAEL 812

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   811 KST-------QSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKV 883
Cdd:TIGR02168  813 TLLneeaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALL 892

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   884 NKEYAESRAEASDLQDKVKEitdtLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSK----ADAWSQEMLQKEKELQ 959
Cdd:TIGR02168  893 RSELEELSEELRELESKRSE----LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEysltLEEAEALENKIEDDEE 968


                   ...
gi 442628159   960 ELR 962
Cdd:TIGR02168  969 EAR 971
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
824-1446 3.04e-17

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 88.17  E-value: 3.04e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  824 LEAANGSLEE-----EAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEkvnkEYAESRAEASDLQ 898
Cdd:PRK02224  182 LSDQRGSLDQlkaqiEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLE----EHEERREELETLE 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  899 DKVKEITDTLhAELQAERSS-SSALHTK---LSKFSDEIA-----TGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQ 969
Cdd:PRK02224  258 AEIEDLRETI-AETEREREElAEEVRDLrerLEELEEERDdllaeAGLDDADAEAVEARREELEDRDEELRDRLEECRVA 336

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  970 DSQTKLKAEGERkeksfeESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEitnaelqhkekmasedaqKIADLKTL 1049
Cdd:PRK02224  337 AQAHNEEAESLR------EDADDLEERAEELREEAAELESELEEAREAVEDRRE------------------EIEELEEE 392

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1050 VEAIQVANANISATNAELSTVLEVLQAEKSETNHifELFEMEADMNSER-LIEKVTGIKEELK----------ETHLQ-L 1117
Cdd:PRK02224  393 IEELRERFGDAPVDLGNAEDFLEELREERDELRE--REAELEATLRTAReRVEEAEALLEAGKcpecgqpvegSPHVEtI 470

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1118 DERQKKFEELEEKLKQAQqseqklqqESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNEs 1197
Cdd:PRK02224  471 EEDRERVEELEAELEDLE--------EEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEE- 541

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1198 nvqlenktsclketqdqllesqkkekqLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQAt 1277
Cdd:PRK02224  542 ---------------------------LRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLER- 593

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1278 nkeLQELLVKSQENEGNLQgeslAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDEsntvlesqkkshneiqDKLEQ 1357
Cdd:PRK02224  594 ---IRTLLAAIADAEDEIE----RLREKREALAELNDERRERLAEKRERKRELEAEFDE----------------ARIEE 650

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1358 AQQKERTLQEETSKLAEQLSQLKQANEELQKSLqqkqlllekgNEFDTQLAEYQKVIDEMDDAASVKSAL------LEQL 1431
Cdd:PRK02224  651 AREDKERAEEYLEQVEEKLDELREERDDLQAEI----------GAVENELEELEELRERREALENRVEALealydeAEEL 720

                         650
                  ....*....|....*
gi 442628159 1432 QNRVAELETALRQAN 1446
Cdd:PRK02224  721 ESMYGDLRAELRQRN 735
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 600-1402 1.12e-16

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 86.56  E-value: 1.12e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   600 EEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLA--EQEKLVREMTENAINQIQLEKESIEQQLALKQNELE 677
Cdd:pfam02463  186 AELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLylDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   678 DFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKeketiikeKEQELQQLQSKS 757
Cdd:pfam02463  266 KLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK--------AEKELKKEKEEI 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   758 AESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKK 837
Cdd:pfam02463  338 EELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQL 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   838 SGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERS 917
Cdd:pfam02463  418 EDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEE 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   918 SSSAL--HTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLqe 995
Cdd:pfam02463  498 RSQKEskARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPL-- 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   996 evTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQ 1075
Cdd:pfam02463  576 --GARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVS 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1076 AEKSETNHIFELFEMEaDMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEI 1155
Cdd:pfam02463  654 LEEGLAEKSEVKASLS-ELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQD 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1156 QQSlQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQlQEEAAKLSGE 1235
Cdd:pfam02463  733 KIN-EELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQE-EELRALEEEL 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1236 LQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGE 1315
Cdd:pfam02463  811 KEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELES 890

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1316 LKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQL 1395
Cdd:pfam02463  891 KEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKE 970


                   ....*..
gi 442628159  1396 LLEKGNE 1402
Cdd:pfam02463  971 ELGKVNL 977
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1151-1467 3.53e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.72  E-value: 3.53e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1151 KLTEIQQSLQELQDSVKQKEELVQNLEekvRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAA 1230
Cdd:TIGR02168  180 KLERTRENLDRLEDILNELERQLKSLE---RQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELE 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1231 KLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLE 1310
Cdd:TIGR02168  257 ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1311 QANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQL----SQLKQANEEL 1386
Cdd:TIGR02168  337 EELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIerleARLERLEDRR 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1387 QKSLQQKQLLLEKGNEfdTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESL 1466
Cdd:TIGR02168  417 ERLQQEIEELLKKLEE--AELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL 494


                   .
gi 442628159  1467 E 1467
Cdd:TIGR02168  495 E 495
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 796-1531 1.21e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.18  E-value: 1.21e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   796 ISQLKSQAEETQSELKSTQSNL---EAKSKQLEAANGSLEEEAKKSghllEQITKLKSEVGETQAALSschtdveskTKQ 872
Cdd:TIGR02168  167 ISKYKERRKETERKLERTRENLdrlEDILNELERQLKSLERQAEKA----ERYKELKAELRELELALL---------VLR 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   873 LEAANAALEKVNKEYAESRAEASDLQDKVKEiTDTLHAELQAErssssalHTKLSKFSDEIATGHKELTSKAdawsQEML 952
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQE-LEEKLEELRLE-------VSELEEEIEELQKELYALANEI----SRLE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   953 QKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTEnlelstgtqttIKDLQERLEITNAELQHK 1032
Cdd:TIGR02168  302 QQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEE-----------LESLEAELEELEAELEEL 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1033 EKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNS-ERLIEKVTGIKEELK 1111
Cdd:TIGR02168  371 ESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElKELQAELEELEEELE 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1112 ETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIE--- 1188
Cdd:TIGR02168  451 ELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSElis 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1189 -------AQNTKLNESnvqLENKTSCLKETQDQLLESQKKEKQ---------LQEEAAKLSGELQQVQEANG--DIKDSL 1250
Cdd:TIGR02168  531 vdegyeaAIEAALGGR---LQAVVVENLNAAKKAIAFLKQNELgrvtflpldSIKGTEIQGNDREILKNIEGflGVAKDL 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1251 VKV-EELVKVLE---------EKLQAATSQ------------LDAQQAT---------NKELQELLVKSQENEgNLQGES 1299
Cdd:TIGR02168  608 VKFdPKLRKALSyllggvlvvDDLDNALELakklrpgyrivtLDGDLVRpggvitggsAKTNSSILERRREIE-ELEEKI 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1300 LAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKS----HNEIQDKLEQAQQKERTLQEETSKLAEQ 1375
Cdd:TIGR02168  687 EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDlarlEAEVEQLEERIAQLSKELTELEAEIEEL 766

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1376 LSQLKQANEELQKSLQQKQLLLEKGNEF-------DTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDA 1448
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLkeelkalREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1449 QKTAYLETKELRRQLESL-----ELEKSREVLS-LKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKNDA 1522
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELeelieELESELEALLnERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ 926


                   ....*....
gi 442628159  1523 LKAKVQTLE 1531
Cdd:TIGR02168  927 LELRLEGLE 935
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1097-1477 2.84e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 81.91  E-value: 2.84e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1097 ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNL 1176
Cdd:COG1196   249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1177 EEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEEL 1256
Cdd:COG1196   329 EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1257 VKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDE 1336
Cdd:COG1196   409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1337 SNTVLESQkkshneiqdkleQAQQKERTLQEETSKLAEQLSQLKQANEELqkslqqkQLLLEKGNEFDTQLAEY------ 1410
Cdd:COG1196   489 AAARLLLL------------LEAEADYEGFLEGVKAALLLAGLRGLAGAV-------AVLIGVEAAYEAALEAAlaaalq 549

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442628159 1411 QKVIDEMDDAASVKSALLEQLQNRVAELE-TALRQANDAQKTAYLETKELRRQLESLELEKSREVLSL 1477
Cdd:COG1196   550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPlDKIRARAALAAALARGAIGAAVDLVASDLREADARYYV 617
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 436-1376 3.96e-15

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 81.37  E-value: 3.96e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   436 EVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEftRKL 515
Cdd:pfam01576   79 ELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKE--RKL 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   516 AEKSVEvlRLSSELQNLKATSDSLEseRVNKTDECEILQTEVRMRDEQ-----IRELNQQLDEVTTQLNVQKADSSALDD 590
Cdd:pfam01576  157 LEERIS--EFTSNLAEEEEKAKSLS--KLKNKHEAMISDLEERLKKEEkgrqeLEKAKRKLEGESTDLQEQIAELQAQIA 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   591 MLRLQKEGTEEK-STLLEKTEKELVQsKEQAAKTLndkEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQL 669
Cdd:pfam01576  233 ELRAQLAKKEEElQAALARLEEETAQ-KNNALKKI---RELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   670 --------------ALKQNELEDFQKKQSES----EVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEK---- 727
Cdd:pfam01576  309 edtldttaaqqelrSKREQEVTELKKALEEEtrshEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESenae 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   728 LQAALEEL---KKEKETIIKEKEQELQQLQSKSAESESA---LKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKS 801
Cdd:pfam01576  389 LQAELRTLqqaKQDSEHKRKKLEGQLQELQARLSESERQraeLAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLES 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   802 QAEETQSELKS---TQSNLEAKSKQLEAANGSL----EEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLE 874
Cdd:pfam01576  469 QLQDTQELLQEetrQKLNLSTRLRQLEDERNSLqeqlEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKK 548

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   875 AANAALEKVNKEYAESRAEASDLQ---DKVKEITDTLHAELQAERSSSSALHTKLSKFSD------EIATGHKELTSKAD 945
Cdd:pfam01576  549 RLQRELEALTQQLEEKAAAYDKLEktkNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQmlaeekAISARYAEERDRAE 628

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   946 AWSQE----MLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKS----------FEESIKNLQEEVTKAKTENLELSTGT 1011
Cdd:pfam01576  629 AEAREketrALSLARALEEALEAKEELERTNKQLRAEMEDLVSSkddvgknvheLERSKRALEQQVEEMKTQLEELEDEL 708

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1012 QTTiKDLQERLEIT--------NAELQHKEKMASED----AQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKS 1079
Cdd:pfam01576  709 QAT-EDAKLRLEVNmqalkaqfERDLQARDEQGEEKrrqlVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQID 787

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1080 ETNHIFElfemEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSL 1159
Cdd:pfam01576  788 AANKGRE----EAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQER 863

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1160 QELQDSV--------------KQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQL 1225
Cdd:pfam01576  864 DELADEIasgasgksalqdekRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQL 943

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1226 QEEAAKLSGELqqvQEANGDIKDslvKVEELVKVLEEKLQAATSQLDaQQATNKELQELLVKSQENEgnLQGESLAVTEK 1305
Cdd:pfam01576  944 ERQNKELKAKL---QEMEGTVKS---KFKSSIAALEAKIAQLEEQLE-QESRERQAANKLVRRTEKK--LKEVLLQVEDE 1014

                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 442628159  1306 LQQLEQangeLKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQL 1376
Cdd:pfam01576 1015 RRHADQ----YKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTLKSKL 1081
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 525-1261 6.18e-15

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 80.45  E-value: 6.18e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   525 LSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKST 604
Cdd:TIGR04523   45 IKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEV 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   605 LLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQS 684
Cdd:TIGR04523  125 ELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLS 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   685 ESEVHLQEIKAQNTQkdfeLVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAL 764
Cdd:TIGR04523  205 NLKKKIQKNKSLESQ----ISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNN 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   765 KVVqvqleqlqqqaaasgEEGSKTVAKLHDEISQLKSQAEetQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQ 844
Cdd:TIGR04523  281 KKI---------------KELEKQLNQLKSEISDLNNQKE--QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQ 343

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   845 ITKLKSEVGETQaalsschTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQdkvkeitdtlhaelqaerSSSSALHT 924
Cdd:TIGR04523  344 ISQLKKELTNSE-------SENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLE------------------SQINDLES 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   925 KLSKFSDEiatgHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTEN 1004
Cdd:TIGR04523  399 KIQNQEKL----NQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLS 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1005 LElstgtqttIKDLQERLEITNAELQHKEKMASEDAQKIADLKtlvEAIQVANANISatnaELSTVLEVLQAEKSETNHI 1084
Cdd:TIGR04523  475 RS--------INKIKQNLEQKQKELKSKEKELKKLNEEKKELE---EKVKDLTKKIS----SLKEKIEKLESEKKEKESK 539

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1085 F-----ELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSL 1159
Cdd:TIGR04523  540 IsdledELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKEL 619

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1160 QELQDSVKQKEELVQNLE---EKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQD---QLLESQKKEKQLQEEAAKLS 1233
Cdd:TIGR04523  620 EKAKKENEKLSSIIKNIKskkNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDdiiELMKDWLKELSLHYKKYITR 699

                          730       740       750
                   ....*....|....*....|....*....|..
gi 442628159  1234 ----GELQQVQEANGDIKDSLVKVEELVKVLE 1261
Cdd:TIGR04523  700 miriKDLPKLEEKYKEIEKELKKLDEFSKELE 731
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1015-1473 1.20e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.60  E-value: 1.20e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1015 IKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADM 1094
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1095 NSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQ 1174
Cdd:COG1196   314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1175 NLEEKVRESSSIIEAQNTKLNESNVQLENKTSC---LKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLV 1251
Cdd:COG1196   394 AAAELAAQLEELEEAEEALLERLERLEEELEELeeaLAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1252 KVEELVKVLEEKLQAATSQLDAQQATNKELQELL--VKSQENEGNLQGESLAVTEKLQ--------QLEQANGELKEALC 1321
Cdd:COG1196   474 LLEAALAELLEELAEAAARLLLLLEAEADYEGFLegVKAALLLAGLRGLAGAVAVLIGveaayeaaLEAALAAALQNIVV 553

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1322 QKENGLKELQGKLDESN----TVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLL 1397
Cdd:COG1196   554 EDDEVAAAAIEYLKAAKagraTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE 633

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 442628159 1398 EKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSRE 1473
Cdd:COG1196   634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 939-1467 1.26e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.60  E-value: 1.26e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  939 ELTSKADAWSQEMLQKEK----ELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTG---T 1011
Cdd:COG1196   228 ELLLLKLRELEAELEELEaeleELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDiarL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1012 QTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEME 1091
Cdd:COG1196   308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1092 ADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEE 1171
Cdd:COG1196   388 LLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1172 LVQNLEEKVRESSSIIEAQNTKLNESNVQLEnktsclKETQDQLLESQKKEKQLQEEAAKLSGELQQVQE---------- 1241
Cdd:COG1196   468 LLEEAALLEAALAELLEELAEAAARLLLLLE------AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGveaayeaale 541

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1242 -------ANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKL-QQLEQAN 1313
Cdd:COG1196   542 aalaaalQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADArYYVLGDT 621

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1314 GELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQlkQANEELQKSLQQK 1393
Cdd:COG1196   622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAE--RLAEEELELEEAL 699

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 442628159 1394 QLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLE 1467
Cdd:COG1196   700 LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1216-1506 1.27e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.60  E-value: 1.27e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1216 LESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVK---VLEEKLQAATSQLDAQQATNKELQELLVKSQENE 1292
Cdd:COG1196   218 LKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAelaELEAELEELRLELEELELELEEAQAEEYELLAEL 297

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1293 GNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKL 1372
Cdd:COG1196   298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1373 AEQLSQLKQANEELQKS-----------LQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETA 1441
Cdd:COG1196   378 EEELEELAEELLEALRAaaelaaqleelEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442628159 1442 LRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKI 1506
Cdd:COG1196   458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGL 522
PTZ00121 PTZ00121
MAEBL; Provisional
 596-1372 1.78e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 79.41  E-value: 1.78e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  596 KEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKE-QLEKQISDLKQLAEQEKlvremTENAiNQIQLEKESIEQQLALKQN 674
Cdd:PTZ00121 1121 KKKAEDARKAEEARKAEDARKAEEARKAEDAKRvEIARKAEDARKAEEARK-----AEDA-KKAEAARKAEEVRKAEELR 1194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  675 ELEDFQK----KQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQL-----EQKTLGHEKLQAALEELKKEKETIIKE 745
Cdd:PTZ00121 1195 KAEDARKaeaaRKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAkkaeeERNNEEIRKFEEARMAHFARRQAAIKA 1274

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  746 KE----QELQQLQS--KSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEA 819
Cdd:PTZ00121 1275 EEarkaDELKKAEEkkKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEA 1354

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  820 KSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAE----AS 895
Cdd:PTZ00121 1355 AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEekkkAD 1434

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  896 DLQDKVKEITDTLHAELQAE--RSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQT 973
Cdd:PTZ00121 1435 EAKKKAEEAKKADEAKKKAEeaKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADE 1514

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  974 KLKAEGERKE---KSFEESIKNLQ----EEVTKA----KTENLELSTGTQTTIKDLQERlEITNAELQHKEKMASEDAQK 1042
Cdd:PTZ00121 1515 AKKAEEAKKAdeaKKAEEAKKADEakkaEEKKKAdelkKAEELKKAEEKKKAEEAKKAE-EDKNMALRKAEEAKKAEEAR 1593

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1043 IADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADmnSERLIEKVTGIKEELKETHLQLDERQK 1122
Cdd:PTZ00121 1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE--EKKKAEELKKAEEENKIKAAEEAKKAE 1671

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1123 KFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEE---KVRESSSIIEAQNTKLNESNV 1199
Cdd:PTZ00121 1672 EDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEEnkiKAEEAKKEAEEDKKKAEEAKK 1751

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1200 QLE--NKTSCLKETQDQLLESQKKEKQL---QEEAAKLSGELQQVQEANGDIKDSLVKVEE-------LVKVLEEKLQAA 1267
Cdd:PTZ00121 1752 DEEekKKIAHLKKEEEKKAEEIRKEKEAvieEELDEEDEKRRMEVDKKIKDIFDNFANIIEggkegnlVINDSKEMEDSA 1831

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1268 TSQLDAQQATNKELQELLVKSQENEGNLQGESlAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKS 1347
Cdd:PTZ00121 1832 IKEVADSKNMQLEEADAFEKHKFNKNNENGED-GNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGK 1910

                         810       820
                  ....*....|....*....|....*.
gi 442628159 1348 HNE-IQDKLEQAQQKERTLQEETSKL 1372
Cdd:PTZ00121 1911 NNDiIDDKLDKDEYIKRDAEETREEI 1936
PTZ00121 PTZ00121
MAEBL; Provisional
 438-1258 4.35e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 78.26  E-value: 4.35e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  438 ESRIAEQLEEEQRLRENVKylneQIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAE 517
Cdd:PTZ00121 1086 DNRADEATEEAFGKAEEAK----KTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAE 1161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  518 --KSVEVLRLSSELQNLKATSDSLE---SERVNKTDEC----------------EILQTEVRMRDEQIR---------EL 567
Cdd:PTZ00121 1162 daRKAEEARKAEDAKKAEAARKAEEvrkAEELRKAEDArkaeaarkaeeerkaeEARKAEDAKKAEAVKkaeeakkdaEE 1241

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  568 NQQLDEVTTQLNVQKADSSALDDMLRLQKEG-TEEKSTLLEKTEKELVQSKEQAAKT--------LNDKEQLEKQISDLK 638
Cdd:PTZ00121 1242 AKKAEEERNNEEIRKFEEARMAHFARRQAAIkAEEARKADELKKAEEKKKADEAKKAeekkkadeAKKKAEEAKKADEAK 1321

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  639 QLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEI--KAQNTQKDFELVESGESLKKLQQ 716
Cdd:PTZ00121 1322 KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAkkKADAAKKKAEEKKKADEAKKKAE 1401

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  717 QLEQKTLGHEKLQAA---LEELKKEKETIIKEKEQELQQLQSKSA-ESESALKVVQVQLEQLQQQAAASGEEGSKTVAKL 792
Cdd:PTZ00121 1402 EDKKKADELKKAAAAkkkADEAKKKAEEKKKADEAKKKAEEAKKAdEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEE 1481

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  793 HDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGsleEEAKKSGHLLEQITKLKSEvgETQAALSSCHTDVESKTKQ 872
Cdd:PTZ00121 1482 AKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA---EEAKKADEAKKAEEAKKAD--EAKKAEEKKKADELKKAEE 1556

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  873 LEAANaalEKVNKEYAESRAEASDLQDKVKEITDTLHaelQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEML 952
Cdd:PTZ00121 1557 LKKAE---EKKKAEEAKKAEEDKNMALRKAEEAKKAE---EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEE 1630

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  953 QKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKnlqEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHK 1032
Cdd:PTZ00121 1631 EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKK---AEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEEL 1707

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1033 EKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKE 1112
Cdd:PTZ00121 1708 KKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDE 1787

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1113 thlqldERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNT 1192
Cdd:PTZ00121 1788 ------EDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENG 1861

                         810       820       830       840       850       860
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 442628159 1193 KLNESNVQLENKTSCLKETQDQLLESqKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVK 1258
Cdd:PTZ00121 1862 EDGNKEADFNKEKDLKEDDEEEIEEA-DEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIK 1926
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 303-913 4.86e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.67  E-value: 4.86e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  303 QDLLREKQQHVEKLmvERDldREDAQnQALQLQKNINELKA-----RIVELESALDNERKKTEELQCSIDEAQFCGDELN 377
Cdd:COG1196   192 EDILGELERQLEPL--ERQ--AEKAE-RYRELKEELKELEAellllKLRELEAELEELEAELEELEAELEELEAELAELE 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  378 AQSQVYKEKIHDLESKITklvsatpslqsilppdlpsddgALQEEIAKLQEkmtiQQKEVESRIAEQLEEEQRLRENVKY 457
Cdd:COG1196   267 AELEELRLELEELELELE----------------------EAQAEEYELLA----ELARLEQDIARLEERRRELEERLEE 320

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  458 LNEQIATLQSELVSKDEALEkfslsecgienlrrelelLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSD 537
Cdd:COG1196   321 LEEELAELEEELEELEEELE------------------ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  538 SLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSK 617
Cdd:COG1196   383 ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL 462

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  618 EQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQN-----ELEDFQKKQSESEVHLQE 692
Cdd:COG1196   463 ELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglagAVAVLIGVEAAYEAALEA 542

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  693 IKAQNTQKDfeLVESGESLKKLQQQLEQKTLG------------HEKLQAALEELKKEKETIIKEKEQELQQLQSKSAES 760
Cdd:COG1196   543 ALAAALQNI--VVEDDEVAAAAIEYLKAAKAGratflpldkiraRAALAAALARGAIGAAVDLVASDLREADARYYVLGD 620

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  761 ESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELkstQSNLEAKSKQLEAANGSLEEEAKKSGH 840
Cdd:COG1196   621 TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRREL---LAALLEAEAELEELAERLAEEELELEE 697

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442628159  841 LLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQ 913
Cdd:COG1196   698 ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1213-1531 5.02e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.79  E-value: 5.02e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1213 DQLLESQKKE-KQLQEEAAKLSGELQQVQEANG---DIKDSLVKVEELVKVLEEKLQAATSQldAQQAtnKELQELlvKS 1288
Cdd:TIGR02168  147 SEIIEAKPEErRAIFEEAAGISKYKERRKETERkleRTRENLDRLEDILNELERQLKSLERQ--AEKA--ERYKEL--KA 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1289 QENEGNLQGESLAVTEKLQQLEQANGELKEA---LCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTL 1365
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAeeeLEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1366 QEETSKLAEQLSQL----KQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETA 1441
Cdd:TIGR02168  301 EQQKQILRERLANLerqlEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1442 LRQANDAQKTAYLETKELRRQLESLELEKSRevlSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKND 1521
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEARLER---LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELE 457

                          330
                   ....*....|
gi 442628159  1522 ALKAKVQTLE 1531
Cdd:TIGR02168  458 RLEEALEELR 467
PTZ00121 PTZ00121
MAEBL; Provisional
 597-1305 2.10e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.95  E-value: 2.10e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  597 EGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTE-NAINQIQLEKESIEQQLALKQNE 675
Cdd:PTZ00121 1080 DFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKaEDARKAEEARKAEDAKRVEIARK 1159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  676 LEDFQK----------KQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKEtiIKE 745
Cdd:PTZ00121 1160 AEDARKaeearkaedaKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEE--AKK 1237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  746 KEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKtvAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLE 825
Cdd:PTZ00121 1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARK--ADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAK 1315

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  826 AAngslEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEIT 905
Cdd:PTZ00121 1316 KA----DEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKK 1391

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  906 DTLHAELQAERSSSSALHTK---LSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERK 982
Cdd:PTZ00121 1392 KADEAKKKAEEDKKKADELKkaaAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKK 1471

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  983 ---------EKSFEESIKNLQEEvTKAKTENLELSTGTQTTIKDLQERLEITNAElqhkEKMASEDAQKIADLKTLVEAI 1053
Cdd:PTZ00121 1472 adeakkkaeEAKKADEAKKKAEE-AKKKADEAKKAAEAKKKADEAKKAEEAKKAD----EAKKAEEAKKADEAKKAEEKK 1546

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1054 QVANANISATNAELSTVLEVLQAEKSETNHIFELFEME-ADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLK 1132
Cdd:PTZ00121 1547 KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEeAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELK 1626

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1133 QAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKlnesnvqlenktsclKETQ 1212
Cdd:PTZ00121 1627 KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE---------------KKAA 1691

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1213 DQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAAtSQLDAQQATNKELQELLVKSQENE 1292
Cdd:PTZ00121 1692 EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKA-EEAKKDEEEKKKIAHLKKEEEKKA 1770

                         730
                  ....*....|...
gi 442628159 1293 GNLQGESLAVTEK 1305
Cdd:PTZ00121 1771 EEIRKEKEAVIEE 1783
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 503-1432 4.14e-13

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 74.70  E-value: 4.14e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   503 QAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQK 582
Cdd:TIGR00606  203 QEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQME 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   583 ADSSALDDMLRLQKEGTEEKSTLLE--------KTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENA 654
Cdd:TIGR00606  283 KDNSELELKMEKVFQGTDEQLNDLYhnhqrtvrEKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEH 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   655 INQIQLEKESIEQQLALKQNELEDFQKKQSESEVHL----QEIKAQNTQKDFELVESGESLKKlqqqlEQKTLGHEKLQA 730
Cdd:TIGR00606  363 IRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLvierQEDEAKTAAQLCADLQSKERLKQ-----EQADEIRDEKKG 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   731 ALEELKKEKETIIKEKEQ---ELQQLQSKSAESESALKVVQVQLEQLQQQAAAsgEEGSKTVAKLHDEISQLKSQAEETQ 807
Cdd:TIGR00606  438 LGRTIELKKEILEKKQEElkfVIKELQQLEGSSDRILELDQELRKAERELSKA--EKNSLTETLKKEVKSLQNEKADLDR 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   808 SELKSTQSNleAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDveskTKQLEAAnaaLEKVNKEY 887
Cdd:TIGR00606  516 KLRKLDQEM--EQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPN----KKQLEDW---LHSKSKEI 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   888 AESRAEASDLQDKVKEITDTLHAELQAERSsssaLHTKLSKFSDEI--ATGHKELTSKADAWSQEMLQKEKELQELRQQL 965
Cdd:TIGR00606  587 NQTRDRLAKLNKELASLEQNKNHINNELES----KEEQLSSYEDKLfdVCGSQDEESDLERLKEEIEKSSKQRAMLAGAT 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   966 QDSQDSQTKLKAEgerkeksfEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIAD 1045
Cdd:TIGR00606  663 AVYSQFITQLTDE--------NQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPG 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1046 LKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFElfEMEADMNSERLIEKVTGIKEELKEthlQLDERQKKFE 1125
Cdd:TIGR00606  735 RQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLG--TIMPEEESAKVCLTDVTIMERFQM---ELKDVERKIA 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1126 ELEEKLKQA--QQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVREsssiieaqntklnesnvqlen 1203
Cdd:TIGR00606  810 QQAAKLQGSdlDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNE--------------------- 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1204 ktscLKETQDQLLESQKKEKQLQEEAAKLSGElqqVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQE 1283
Cdd:TIGR00606  869 ----LKSEKLQIGTNLQRRQQFEEQLVELSTE---VQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQD 941

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1284 LLVKSQENEGNLQGESLAVTEKLQQLEQangelkEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKER 1363
Cdd:TIGR00606  942 KVNDIKEKVKNIHGYMKDIENKIQDGKD------DYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQER 1015

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 442628159  1364 TLQEETS--KLAEQLSQLKQANEELQKSLQQKQLLLEKgnefdtqlAEYQKVIDEMDDAASVKSALLEQLQ 1432
Cdd:TIGR00606 1016 WLQDNLTlrKRENELKEVEEELKQHLKEMGQMQVLQMK--------QEHQKLEENIDLIKRNHVLALGRQK 1078
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 949-1467 1.01e-12

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 73.13  E-value: 1.01e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   949 QEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEevTKAKTENLELS-TGTQTTIKDLQERLEITNA 1027
Cdd:TIGR04523  117 EQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYND--LKKQKEELENElNLLEKEKLNIQKNIDKIKN 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1028 ELQHKEKMASEDAQKIADLKTLVEAIqvanANISATNAELSTVLEVLQAEKSETNHIFElfemEADMNSERLIEKVTGIK 1107
Cdd:TIGR04523  195 KLLKLELLLSNLKKKIQKNKSLESQI----SELKKQNNQLKDNIEKKQQEINEKTTEIS----NTQTQLNQLKDEQNKIK 266

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1108 EELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQtskeklteiQQSLQELQDSVKQKEELVQNLEEKVRESSSII 1187
Cdd:TIGR04523  267 KQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKE---------QDWNKELKSELKNQEKKLEEIQNQISQNNKII 337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1188 EAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAA 1267
Cdd:TIGR04523  338 SQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKL 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1268 TSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKS 1347
Cdd:TIGR04523  418 QQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKE 497

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1348 HNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKgNEFDTQLAEYQKVIDEMDDAasvksal 1427
Cdd:TIGR04523  498 LKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNK-DDFELKKENLEKEIDEKNKE------- 569

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|
gi 442628159  1428 LEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLE 1467
Cdd:TIGR04523  570 IEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKE 609
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 303-1196 1.52e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.79  E-value: 1.52e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   303 QDLLREKQQHVEKLMVERDldrEDAQNQALQLQKNINELKARIVELESA---LDNERKKTEELQCSIDEAQFCGDELNAQ 379
Cdd:TIGR02169  190 DLIIDEKRQQLERLRRERE---KAERYQALLKEKREYEGYELLKEKEALerqKEAIERQLASLEEELEKLTEEISELEKR 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   380 SQVYKEKIHDLESKITKLVSatpslqsilppdlpsddgalqEEIAKLQEKM---TIQQKEVESRIAEQLEEEQRLRENVK 456
Cdd:TIGR02169  267 LEEIEQLLEELNKKIKDLGE---------------------EEQLRVKEKIgelEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   457 YLNEQIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFtrklAEKSVEVLRLSSELQNLKATS 536
Cdd:TIGR02169  326 KLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF----AETRDELKDYREKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   537 DSLESERvnktdecEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQS 616
Cdd:TIGR02169  402 NELKREL-------DRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDL 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   617 KEQAAKTLNDKEQLEKQISDLKqlAEQEKLVREMTENAINQIQLeKESIEQQLALKQNELEDFQKKQSESEVhlqeikAQ 696
Cdd:TIGR02169  475 KEEYDRVEKELSKLQRELAEAE--AQARASEERVRGGRAVEEVL-KASIQGVHGTVAQLGSVGERYATAIEV------AA 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   697 NTQKDFELVESGESLKKLQQQLEQKTLGH------EKLQAALEELKKEKE---------------------------TII 743
Cdd:TIGR02169  546 GNRLNNVVVEDDAVAKEAIELLKRRKAGRatflplNKMRDERRDLSILSEdgvigfavdlvefdpkyepafkyvfgdTLV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   744 KEKEQELQQLQSK----SAESE----SALKVVQVQLEQLQQQAAASGEEgskTVAKLHDEISQLKSQAEETQSELKSTQS 815
Cdd:TIGR02169  626 VEDIEAARRLMGKyrmvTLEGElfekSGAMTGGSRAPRGGILFSRSEPA---ELQRLRERLEGLKRELSSLQSELRRIEN 702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   816 NLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSChtdveskTKQLEAANAALEKVNKEYAESRAEAS 895
Cdd:TIGR02169  703 RLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL-------EQEIENVKSELKELEARIEELEEDLH 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   896 DLQDKVKEITDTL-HAELQAERSSSSALHTKLSKFSDEIATGHKELTSKadawSQEMLQKEKELQELRQQLqdsqdsqtk 974
Cdd:TIGR02169  776 KLEEALNDLEARLsHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRL----TLEKEYLEKEIQELQEQR--------- 842

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   975 lkAEGERKEKSFEESIKNLQEEVTKAKTENLELstgtQTTIKDLQERLeitnaelqhkEKMASEDAQKIADLKTLVEAIQ 1054
Cdd:TIGR02169  843 --IDLKEQIKSIEKEIENLNGKKEELEEELEEL----EAALRDLESRL----------GDLKKERDELEAQLRELERKIE 906

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1055 VANANISATNAELSTVLEVLQAEKSETNHifelfemeadmnserlIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQA 1134
Cdd:TIGR02169  907 ELEAQIEKKRKRLSELKAKLEALEEELSE----------------IEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRAL 970

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442628159  1135 QQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRES-SSIIEAQNTKLNE 1196
Cdd:TIGR02169  971 EPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREVfMEAFEAINENFNE 1033
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 559-1378 1.68e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 72.84  E-value: 1.68e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   559 MRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELvqskeQAAKTLNdkeqlEKQISDLK 638
Cdd:pfam15921  100 LHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL-----EAAKCLK-----EDMLEDSN 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   639 QLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNEledfqkKQSESEVHLQEIKAQNTQKDFELVESGESLK----KL 714
Cdd:pfam15921  170 TQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYE------HDSMSTMHFRSLGSAISKILRELDTEISYLKgrifPV 243

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   715 QQQLEQ-KTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLH 793
Cdd:pfam15921  244 EDQLEAlKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLE 323

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   794 DEISQLKSQAEETQselKSTQSNLEAKSKQLEAANGSLEEE-------AKKSGHLLEQITKLKSEVGETQAALSSCHTDV 866
Cdd:pfam15921  324 STVSQLRSELREAK---RMYEDKIEELEKQLVLANSELTEArterdqfSQESGNLDDQLQKLLADLHKREKELSLEKEQN 400

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   867 ESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSdeiatghkELTSKADA 946
Cdd:pfam15921  401 KRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVS--------SLTAQLES 472

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   947 wSQEMLQKEKElqelrqqlqdsqdSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLElstgtqttIKDLQERLEITN 1026
Cdd:pfam15921  473 -TKEMLRKVVE-------------ELTAKKMTLESSERTVSDLTASLQEKERAIEATNAE--------ITKLRSRVDLKL 530

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1027 AELQHkekmasedaqkiadLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGI 1106
Cdd:pfam15921  531 QELQH--------------LKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLE 596

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1107 KE------ELKETHLQLDERQKKFEELE--------EKLKQAQQSEQKLQQESQTSKEK---LTEIQQSLQELQDSVKQK 1169
Cdd:pfam15921  597 KEindrrlELQEFKILKDKKDAKIRELEarvsdlelEKVKLVNAGSERLRAVKDIKQERdqlLNEVKTSRNELNSLSEDY 676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1170 EELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDS 1249
Cdd:pfam15921  677 EVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEA 756

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1250 LVKVEELVKVLEEKLQAATSQLDA-QQATNKELQEL-LVKSQEN---------EGNLQGESLAVTE---KLQQLEQANGE 1315
Cdd:pfam15921  757 MTNANKEKHFLKEEKNKLSQELSTvATEKNKMAGELeVLRSQERrlkekvanmEVALDKASLQFAEcqdIIQRQEQESVR 836

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 442628159  1316 LKealCQKENGLKELQGKLDESNTVLE-------SQKKSHNEIQDK------LEQAQQKERTLQEETSKLAEQLSQ 1378
Cdd:pfam15921  837 LK---LQHTLDVKELQGPGYTSNSSMKprllqpaSFTRTHSNVPSSqstasfLSHHSRKTNALKEDPTRDLKQLLQ 909
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
587-1177 2.49e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 71.99  E-value: 2.49e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  587 ALDDMLRLQKEGTEE-KSTLLEKTEKELVqskeqaaKTLNDKEQLEKQI-SDLKQLAEQEKLVREMTENAINQIQLEKES 664
Cdd:PRK02224  177 GVERVLSDQRGSLDQlKAQIEEKEEKDLH-------ERLNGLESELAELdEEIERYEEQREQARETRDEADEVLEEHEER 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  665 IEQQLALKQnELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIK 744
Cdd:PRK02224  250 REELETLEA-EIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRD 328

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  745 EKEQELQQLQSKSAESESALKVVQVQLEQLqqqaaasgeegsktvAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQL 824
Cdd:PRK02224  329 RLEECRVAAQAHNEEAESLREDADDLEERA---------------EELREEAAELESELEEAREAVEDRREEIEELEEEI 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  825 EAANGS-------LEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDL 897
Cdd:PRK02224  394 EELRERfgdapvdLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEED 473

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  898 QDKVKEITDTLhAELQAERSSSSALHTKLSKFSdEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKA 977
Cdd:PRK02224  474 RERVEELEAEL-EDLEEEVEEVEERLERAEDLV-EAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEA 551

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  978 EGERKEKSFEESIKNLQEevtkaktenlelstgTQTTIKDLQERLEITNAELQHKEKMASEDAqKIADLKTLVEAIQVAN 1057
Cdd:PRK02224  552 EAEEKREAAAEAEEEAEE---------------AREEVAELNSKLAELKERIESLERIRTLLA-AIADAEDEIERLREKR 615

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1058 ANISATNAELSTVLevlqAEKSETNHifelfEMEADMNSERLiekvtgikEELKETHLQLDERQkkfEELEEKLKQAQQS 1137
Cdd:PRK02224  616 EALAELNDERRERL----AEKRERKR-----ELEAEFDEARI--------EEAREDKERAEEYL---EQVEEKLDELREE 675

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|
gi 442628159 1138 EQKLQQESQTSKEKLTEiqqsLQELQDSVKQKEELVQNLE 1177
Cdd:PRK02224  676 RDDLQAEIGAVENELEE----LEELRERREALENRVEALE 711
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
787-1376 2.62e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 72.02  E-value: 2.62e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  787 KTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKsghlLEQITKLKSEVGETQAALSSCHTDV 866
Cdd:PRK03918  172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREE----LEKLEKEVKELEELKEEIEELEKEL 247

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  867 ESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITdtlhaELQAERSSSSALHTKLSKFSDEIATGHKELTSkada 946
Cdd:PRK03918  248 ESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-----ELKEKAEEYIKLSEFYEEYLDELREIEKRLSR---- 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  947 WSQEMLQKEKELQELRQQLQDSQDSQTKLKaEGERKEKSFEESIKNLQEevTKAKTENLE-----LSTGTQTTIKDLQER 1021
Cdd:PRK03918  319 LEEEINGIEERIKELEEKEERLEELKKKLK-ELEKRLEELEERHELYEE--AKAKKEELErlkkrLTGLTPEKLEKELEE 395

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1022 LEITNAELQHKEK----MASEDAQKIADLKTLVEAIQVANANISATNAELS-----TVLEVLQAE-KSETNHIFELFEME 1091
Cdd:PRK03918  396 LEKAKEEIEEEISkitaRIGELKKEIKELKKAIEELKKAKGKCPVCGRELTeehrkELLEEYTAElKRIEKELKEIEEKE 475

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1092 ADMNSE-RLIEKVTGIKEEL---KETHLQLDERQKKFEELE-EKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSV 1166
Cdd:PRK03918  476 RKLRKElRELEKVLKKESELiklKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELK 555

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1167 KQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDI 1246
Cdd:PRK03918  556 KKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEEL 635

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1247 KDSLVKVEELVKVLEEKLQAATsqldaqQATNKELQELLVKsqenegnLQGESLAVTEKLQQLEQANGELKEALCQKENG 1326
Cdd:PRK03918  636 AETEKRLEELRKELEELEKKYS------EEEYEELREEYLE-------LSRELAGLRAELEELEKRREEIKKTLEKLKEE 702

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|..
gi 442628159 1327 LKELQGKLDESNtVLESQKKSHNEIQDKLE--QAQQKERTLQeETSKLAEQL 1376
Cdd:PRK03918  703 LEEREKAKKELE-KLEKALERVEELREKVKkyKALLKERALS-KVGEIASEI 752
PRK11281 PRK11281
mechanosensitive channel MscK;
1106-1482 7.16e-12

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 70.71  E-value: 7.16e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1106 IKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQesqtskeklteIQQSLQELQDSvkQKEELVQNLeekvrESSS 1185
Cdd:PRK11281   61 VQQDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQ-----------AQAELEALKDD--NDEETRETL-----STLS 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1186 IIEAQNtKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQeeaAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQ 1265
Cdd:PRK11281  123 LRQLES-RLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQ---AALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQ 198

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1266 AATSQLDAQQ-------ATNKELQELLvKSQENEgnlqgeslaVTEKLQQLEQANGELKEALCQKEngLKELQGKLDESN 1338
Cdd:PRK11281  199 AEQALLNAQNdlqrkslEGNTQLQDLL-QKQRDY---------LTARIQRLEHQLQLLQEAINSKR--LTLSEKTVQEAQ 266

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1339 TVLESQKKSHNE-IQDKLEQAQQKERTLQEETSKLAE----------QLSQLKQAN---EE----LQKSL-------QQK 1393
Cdd:PRK11281  267 SQDEAARIQANPlVAQELEINLQLSQRLLKATEKLNTltqqnlrvknWLDRLTQSErniKEqisvLKGSLllsrilyQQQ 346

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1394 QLL--LEKGNEFDTQLAE---YQKVIDEMDDAasvksalLEQLQNRVAELEtalrqANDAQKtaylETKELRRQLESLeL 1468
Cdd:PRK11281  347 QALpsADLIEGLADRIADlrlEQFEINQQRDA-------LFQPDAYIDKLE-----AGHKSE----VTDEVRDALLQL-L 409

                         410
                  ....*....|....*....
gi 442628159 1469 EKSREVL-----SLKAQMN 1482
Cdd:PRK11281  410 DERRELLdqlnkQLNNQLN 428
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1016-1478 7.83e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 70.48  E-value: 7.83e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1016 KDLQERLEITNAELQHKEK--MASEDAQ-KIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEmEA 1092
Cdd:PRK03918  165 KNLGEVIKEIKRRIERLEKfiKRTENIEeLIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE-EL 243

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1093 DMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKlQQESQTSKEKLTEIQQSLQELQDSVKQKEEL 1172
Cdd:PRK03918  244 EKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEK-AEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1173 VQNLEEKVRESSSIiEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSG--------ELQQVQEANG 1244
Cdd:PRK03918  323 INGIEERIKELEEK-EERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGltpeklekELEELEKAKE 401

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1245 DIKDSLVKVEELVKVLEEK---LQAATSQLDAQQAT----NKELQEllvksqENEGNLQGEslaVTEKLQQLEQANGELK 1317
Cdd:PRK03918  402 EIEEEISKITARIGELKKEikeLKKAIEELKKAKGKcpvcGRELTE------EHRKELLEE---YTAELKRIEKELKEIE 472

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1318 EALCQKENGLKELQGKLDESNTV------------LESQKKSHNeiQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEE 1385
Cdd:PRK03918  473 EKERKLRKELRELEKVLKKESELiklkelaeqlkeLEEKLKKYN--LEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEK 550

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1386 LQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAAsvksalLEQLQNRVAELETALRQANDAQKTAY-LETKELRRQLE 1464
Cdd:PRK03918  551 LEELKKKLAELEKKLDELEEELAELLKELEELGFES------VEELEERLKELEPFYNEYLELKDAEKeLEREEKELKKL 624

                         490
                  ....*....|....
gi 442628159 1465 SLELEKSREVLSLK 1478
Cdd:PRK03918  625 EEELDKAFEELAET 638
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 297-927 9.42e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 70.15  E-value: 9.42e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   297 KSQFSMQDLLREKQQHVEKLMVERD----LDREDAQNQA---LQLQKNINELKARIVELESALDNERKKTEELQ------ 363
Cdd:pfam15921  103 KQKFYLRQSVIDLQTKLQEMQMERDamadIRRRESQSQEdlrNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRkmmlsh 182

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   364 ---------CSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDGALQEEIAKLQEKMTI-- 432
Cdd:pfam15921  183 egvlqeirsILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELll 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   433 --QQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSEL-VSKDEALEKFSLSECGIENLRRELELLKEenekQAQEAQA 509
Cdd:pfam15921  263 qqHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLeIIQEQARNQNSMYMRQLSDLESTVSQLRS----ELREAKR 338

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   510 EFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQI---RELNQQL-----------DEVT 575
Cdd:pfam15921  339 MYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELsleKEQNKRLwdrdtgnsitiDHLR 418

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   576 TQLNVQKADSSALDDMLRLQKE----GTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLK----QLAEQEKLV 647
Cdd:pfam15921  419 RELDDRNMEVQRLEALLKAMKSecqgQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTakkmTLESSERTV 498

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   648 REMT------ENAINQIQLEKESIEQQLALKQNELEDFQKKQSesevHLQEIKAQNTQKDFELVESGESLKKLQQQLEQK 721
Cdd:pfam15921  499 SDLTaslqekERAIEATNAEITKLRSRVDLKLQELQHLKNEGD----HLRNVQTECEALKLQMAEKDKVIEILRQQIENM 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   722 TL---GHEKLQAALEELKKEKETIIKEKEQELQQ---LQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDE 795
Cdd:pfam15921  575 TQlvgQHGRTAGAMQVEKAQLEKEINDRRLELQEfkiLKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQE 654

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   796 ISQLKSQAEETQSELKS-------TQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQI-TKLKSEVGETQAALS---SCHT 864
Cdd:pfam15921  655 RDQLLNEVKTSRNELNSlsedyevLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTrNTLKSMEGSDGHAMKvamGMQK 734

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442628159   865 DVESKTKQLEAANA-------ALEKVNKEYAESRAEASDLQDKVKEIT---DTLHAELQAERSSSSALHTKLS 927
Cdd:pfam15921  735 QITAKRGQIDALQSkiqfleeAMTNANKEKHFLKEEKNKLSQELSTVAtekNKMAGELEVLRSQERRLKEKVA 807
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
588-1182 1.89e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 69.32  E-value: 1.89e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  588 LDDMLRLQKEGTEEKSTLLEKTE------KELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLE 661
Cdd:PRK03918  167 LGEVIKEIKRRIERLEKFIKRTEnieeliKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKE 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  662 KESIEQQLALKQNELEDFQKKQSESEVHLQEI--KAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELkkek 739
Cdd:PRK03918  247 LESLEGSKRKLEEKIRELEERIEELKKEIEELeeKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEE---- 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  740 etiIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQaaasgeegsKTVAKLHDEISQLKSQAEETQSELKS-TQSNLE 818
Cdd:PRK03918  323 ---INGIEERIKELEEKEERLEELKKKLKELEKRLEEL---------EERHELYEEAKAKKEELERLKKRLTGlTPEKLE 390

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  819 AKSKQLEAANGSLEEEAKKsghLLEQITKLKSEVGETQAALSSCHT------------DVESKTKQLEAANAALEKVNKE 886
Cdd:PRK03918  391 KELEELEKAKEEIEEEISK---ITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIEKE 467

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  887 YAESRAEASDLQDKVKEITDTLHAELQAerssssalhTKLSKFSDEIatghKELTSKADAWSQEML-QKEKELQELRQQL 965
Cdd:PRK03918  468 LKEIEEKERKLRKELRELEKVLKKESEL---------IKLKELAEQL----KELEEKLKKYNLEELeKKAEEYEKLKEKL 534

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  966 QDSQDSQTKLKAEGERKE------KSFEESIKNLQEEVTKAKTENLELSTGtqtTIKDLQERLEitNAELQHKEKMASED 1039
Cdd:PRK03918  535 IKLKGEIKSLKKELEKLEelkkklAELEKKLDELEEELAELLKELEELGFE---SVEELEERLK--ELEPFYNEYLELKD 609

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1040 AQKiaDLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFemeadmnSERLIEKVTGIKEELKETHLQLDE 1119
Cdd:PRK03918  610 AEK--ELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKY-------SEEEYEELREEYLELSRELAGLRA 680

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442628159 1120 RqkkFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQqslqelqdSVKQKEELVQNLEEKVRE 1182
Cdd:PRK03918  681 E---LEELEKRREEIKKTLEKLKEELEEREKAKKELE--------KLEKALERVEELREKVKK 732
mukB PRK04863
chromosome partition protein MukB;
1098-1472 1.92e-11

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 69.60  E-value: 1.92e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1098 RLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQElqdsvkqkeelvQNLE 1177
Cdd:PRK04863  283 VHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQ------------QEKI 350

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1178 EKVRESssiieaqntkLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEAngdikdslvkveelv 1257
Cdd:PRK04863  351 ERYQAD----------LEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQA--------------- 405

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1258 kvleeklqaatsqLDAQQATNKELQELLVKSQENEGNLQGESLAVT---EKLQQLEQANGELKEALCQKENGLKELQGKL 1334
Cdd:PRK04863  406 -------------LDVQQTRAIQYQQAVQALERAKQLCGLPDLTADnaeDWLEEFQAKEQEATEELLSLEQKLSVAQAAH 472

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1335 DESNTVLESQKKSHNEI--QDKLEQAQQKERTLQEEtSKLAEQLSQLKQANEELQKSLQQKQLLLEkgnefdtQLAEYQK 1412
Cdd:PRK04863  473 SQFEQAYQLVRKIAGEVsrSEAWDVARELLRRLREQ-RHLAEQLQQLRMRLSELEQRLRQQQRAER-------LLAEFCK 544

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1413 VIDEMDDAAsvksALLEQLQnrvAELETALRQANDAQKTAYLETKELRRQLESLELEKSR 1472
Cdd:PRK04863  545 RLGKNLDDE----DELEQLQ---EELEARLESLSESVSEARERRMALRQQLEQLQARIQR 597
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 802-1493 2.06e-11

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 69.23  E-value: 2.06e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   802 QAEETQSELKSTQSNLEAKSKQLEAANgSLEEEAKKSGHLLEQITKLKSEVGETQAALsschtDVESKTKQLEAANAALE 881
Cdd:TIGR00618  230 HLREALQQTQQSHAYLTQKREAQEEQL-KKQQLLKQLRARIEELRAQEAVLEETQERI-----NRARKAAPLAAHIKAVT 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   882 KVNKEYAESRAEasdLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKEL-TSKADAWSQEMLQKEKELQE 960
Cdd:TIGR00618  304 QIEQQAQRIHTE---LQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDaHEVATSIREISCQQHTLTQH 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   961 LRQQLQDSQDSQTKLKAEGERKEKsfeesiknLQEEVTKAKTENLELSTGTQ------TTIKDLQERLEITNA------- 1027
Cdd:TIGR00618  381 IHTLQQQKTTLTQKLQSLCKELDI--------LQREQATIDTRTSAFRDLQGqlahakKQQELQQRYAELCAAaitctaq 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1028 ELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSE--------TNHIFELFEMEADMNS-ER 1098
Cdd:TIGR00618  453 CEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPlcgscihpNPARQDIDNPGPLTRRmQR 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1099 LIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSvkqkeelvqnLEE 1178
Cdd:TIGR00618  533 GEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDL----------TEK 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1179 KVRESSSIIEAQNTKLNESNVQLENktsclketQDQLLESQKKEKQLQEEAAKLSGELQQVqeANGDIKDSLVKVEELVK 1258
Cdd:TIGR00618  603 LSEAEDMLACEQHALLRKLQPEQDL--------QDVRLHLQQCSQELALKLTALHALQLTL--TQERVREHALSIRVLPK 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1259 VLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1338
Cdd:TIGR00618  673 ELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQA 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1339 TvlESQKKSHNEIQDKLEQAQQKERTLQEetsklaeqLSQLKQANEELQKSLQQKQLLLEkgnefdTQLAEYQKVIDEMD 1418
Cdd:TIGR00618  753 R--TVLKARTEAHFNNNEEVTAALQTGAE--------LSHLAAEIQFFNRLREEDTHLLK------TLEAEIGQEIPSDE 816

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 442628159  1419 DAASVKSALL----EQLQNRVAELETALRQAndaqKTAYLETKELRRQLESLeLEKSREVLSLKAQMNGASSRSGKGDE 1493
Cdd:TIGR00618  817 DILNLQCETLvqeeEQFLSRLEEKSATLGEI----THQLLKYEECSKQLAQL-TQEQAKIIQLSDKLNGINQIKIQFDG 890
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 563-1467 2.34e-11

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 69.05  E-value: 2.34e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   563 QIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEK--TEKEL-VQSKEQAAKTLNDKEQLEKQISDLKQ 639
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQlqAETELcAEAEEMRARLAARKQELEEILHELES 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   640 LAEQEklvremtENAINQIQLEKESIEQQLAlkqneledfqkkqsESEVHLQEIKAQNTQKDFELVESGESLKKLQQQ-- 717
Cdd:pfam01576   83 RLEEE-------EERSQQLQNEKKKMQQHIQ--------------DLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDil 141

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   718 -LEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALkvvqVQLEQLQQQAAASGEEGSKTVAKLHDEI 796
Cdd:pfam01576  142 lLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMI----SDLEERLKKEEKGRQELEKAKRKLEGES 217

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   797 SQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQ---- 872
Cdd:pfam01576  218 TDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQrrdl 297

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   873 ---LEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQ 949
Cdd:pfam01576  298 geeLEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEK 377

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   950 EMLQKEKELQELrqqlQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELstgtQTTIKDLQERLEITNAEL 1029
Cdd:pfam01576  378 AKQALESENAEL----QAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAEL----AEKLSKLQSELESVSSLL 449

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1030 QHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELfEMEADMNSERliekvtgikeE 1109
Cdd:pfam01576  450 NEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEE-EEEAKRNVER----------Q 518

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1110 LKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTE--------------IQQSLQELQDSVKQKEELVQN 1175
Cdd:pfam01576  519 LSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEkaaaydklektknrLQQELDDLLVDLDHQRQLVSN 598

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1176 LEEKVRESSSII---EAQNTKLNESNVQLENK-----------TSCLKETQDQLLESQKKEKQLQEEAAKL--------- 1232
Cdd:pfam01576  599 LEKKQKKFDQMLaeeKAISARYAEERDRAEAEareketralslARALEEALEAKEELERTNKQLRAEMEDLvsskddvgk 678

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1233 ------------SGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQ----LDAQQATNKELQELLVKS-------Q 1289
Cdd:pfam01576  679 nvhelerskralEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQferdLQARDEQGEEKRRQLVKQvreleaeL 758

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1290 ENEGNLQGESLAVTEKLQ--------QLEQANGELKEALCQkengLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQK 1361
Cdd:pfam01576  759 EDERKQRAQAVAAKKKLEldlkeleaQIDAANKGREEAVKQ----LKKLQAQMKDLQRELEEARASRDEILAQSKESEKK 834

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1362 ERTLQEETSKLAEQLSQLKQAN-----------EELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE-------MDDAASV 1423
Cdd:pfam01576  835 LKNLEAELLQLQEDLAASERARrqaqqerdelaDEIASGASGKSALQDEKRRLEARIAQLEEELEEeqsntelLNDRLRK 914

                          970       980       990      1000
                   ....*....|....*....|....*....|....*....|....
gi 442628159  1424 KSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLE 1467
Cdd:pfam01576  915 STLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEME 958
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1260-1487 5.64e-11

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 67.35  E-value: 5.64e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1260 LEEKLQAATSQLDAQQAtnkELQELlvKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNT 1339
Cdd:COG3206   180 LEEQLPELRKELEEAEA---ALEEF--RQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPD 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1340 VLESQKKShNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQlllekgnefdtqlAEYQKVIDEMDD 1419
Cdd:COG3206   255 ALPELLQS-PVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQ-------------QEAQRILASLEA 320

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442628159 1420 AASVKSALLEQLQNRVAELETALRQANDAQKtaylETKELRRQLESLE-----LEKSREVLSLKAQMNGASSR 1487
Cdd:COG3206   321 ELEALQAREASLQAQLAQLEARLAELPELEA----ELRRLEREVEVARelyesLLQRLEEARLAEALTVGNVR 389
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1065-1526 5.80e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 67.76  E-value: 5.80e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1065 AELSTVLEVLQAEKSETNHIFELFEMEADMNSERLiEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQE 1144
Cdd:PRK02224  202 KDLHERLNGLESELAELDEEIERYEEQREQARETR-DEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEE 280

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1145 SQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQ 1224
Cdd:PRK02224  281 VRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEE 360

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1225 LQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQEllvksqenegnlqgESLAVTE 1304
Cdd:PRK02224  361 LREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELRE--------------ERDELRE 426

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1305 KLQQLEqanGELKEAlcqkENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQ--- 1381
Cdd:PRK02224  427 REAELE---ATLRTA----RERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEErle 499

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1382 ANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAAsvksallEQLQNRVAELETALRQANDAQKTAYLETKELRR 1461
Cdd:PRK02224  500 RAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERA-------EELRERAAELEAEAEEKREAAAEAEEEAEEARE 572

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 442628159 1462 QLESLEleksrevlslkaqmngaSSRSGKGDEVESLD-IETSLAKINFLNSIIADMQQKNDALKAK 1526
Cdd:PRK02224  573 EVAELN-----------------SKLAELKERIESLErIRTLLAAIADAEDEIERLREKREALAEL 621
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1189-1394 5.84e-11

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 66.33  E-value: 5.84e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1189 AQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAAT 1268
Cdd:COG4942    17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1269 SQLDAQQatnKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSH 1348
Cdd:COG4942    97 AELEAQK---EELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 442628159 1349 NEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQ 1394
Cdd:COG4942   174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQ 219
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
318-903 1.09e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 66.63  E-value: 1.09e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  318 VERDLDREDAQNQALQLQKNINELKARIVELESALdnerKKTEELQCSIDEAqfcGDELNAQSQVYKE---KIHDLESKI 394
Cdd:PRK03918  151 VRQILGLDDYENAYKNLGEVIKEIKRRIERLEKFI----KRTENIEELIKEK---EKELEEVLREINEissELPELREEL 223

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  395 TKLVSATPSLQSI--LPPDLPSDDGALQEEIAKLQEKMtiqqKEVESRIAEQLEEEQRLRENVKYLNEqiatlQSELVSK 472
Cdd:PRK03918  224 EKLEKEVKELEELkeEIEELEKELESLEGSKRKLEEKI----RELEERIEELKKEIEELEEKVKELKE-----LKEKAEE 294

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  473 DEALEKFslsecgienlrrelellkeenekqaqeaQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLEServnktdecei 552
Cdd:PRK03918  295 YIKLSEF----------------------------YEEYLDELREIEKRLSRLEEEINGIEERIKELEE----------- 335

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  553 lqtevrmRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTL----LEKTEKELVQSKEQAAKTLNDKE 628
Cdd:PRK03918  336 -------KEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLtgltPEKLEKELEELEKAKEEIEEEIS 408

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  629 QLEKQISDLKQLAEQEKLV---------------REMTE----NAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVH 689
Cdd:PRK03918  409 KITARIGELKKEIKELKKAieelkkakgkcpvcgRELTEehrkELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKV 488

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  690 LQEIKAQNTQKDF--ELVESGESLKKLQ-QQLEQKTLGHEKLQAALEELKKEKETIIKEKEqELQQLQSKSAESESALKV 766
Cdd:PRK03918  489 LKKESELIKLKELaeQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLKKELE-KLEELKKKLAELEKKLDE 567

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  767 VQVQLEQLQQQAaasGEEGSKTVAKLHDEISQLKSQAEEtQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQIT 846
Cdd:PRK03918  568 LEEELAELLKEL---EELGFESVEELEERLKELEPFYNE-YLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLE 643

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 442628159  847 KLKSEVGETQAALS-SCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKE 903
Cdd:PRK03918  644 ELRKELEELEKKYSeEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKE 701
PTZ00121 PTZ00121
MAEBL; Provisional
 871-1489 1.20e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 66.70  E-value: 1.20e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  871 KQLEAANAAlEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIAT--GHKELTSKAD-AW 947
Cdd:PTZ00121 1200 RKAEAARKA-EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAhfARRQAAIKAEeAR 1278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  948 SQEMLQKEKELQ---ELRQQLQDSQDSQTKLKAEGERKE---KSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQER 1021
Cdd:PTZ00121 1279 KADELKKAEEKKkadEAKKAEEKKKADEAKKKAEEAKKAdeaKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADE 1358

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1022 LEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAE---------KSETNHIFELFEMEA 1092
Cdd:PTZ00121 1359 AEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAaakkkadeaKKKAEEKKKADEAKK 1438

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1093 DMNSERLIEKVTGIKEELK--ETHLQLDERQKKFEELEEKLKQAQQSEQkLQQESQTSKEKLTEIQQSLQELQ--DSVKQ 1168
Cdd:PTZ00121 1439 KAEEAKKADEAKKKAEEAKkaEEAKKKAEEAKKADEAKKKAEEAKKADE-AKKKAEEAKKKADEAKKAAEAKKkaDEAKK 1517

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1169 KEELVQNLE-EKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIK 1247
Cdd:PTZ00121 1518 AEEAKKADEaKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEV 1597

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1248 DSLVKVEELVKVlEEKLQAATSQLDAQQATNKELQEllvKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKEngl 1327
Cdd:PTZ00121 1598 MKLYEEEKKMKA-EEAKKAEEAKIKAEELKKAEEEK---KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA--- 1670

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1328 KELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKE--RTLQEETSKLAEQL-----------SQLKQANEELQKSLQQKQ 1394
Cdd:PTZ00121 1671 EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEelKKKEAEEKKKAEELkkaeeenkikaEEAKKEAEEDKKKAEEAK 1750

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1395 LLLEKGNEFDTQLAEYQKVIDEM--DDAASVKSALLEQLQNRVAELETALRQA------------------NDAQKTAYL 1454
Cdd:PTZ00121 1751 KDEEEKKKIAHLKKEEEKKAEEIrkEKEAVIEEELDEEDEKRRMEVDKKIKDIfdnfaniieggkegnlviNDSKEMEDS 1830

                         650       660       670
                  ....*....|....*....|....*....|....*
gi 442628159 1455 ETKELRRQlESLELEKSREVLSLKAQMNGASSRSG 1489
Cdd:PTZ00121 1831 AIKEVADS-KNMQLEEADAFEKHKFNKNNENGEDG 1864
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 331-1234 1.23e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 66.53  E-value: 1.23e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   331 ALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQFCGDEL-NAQSQVYKEKIHDLESKITKLVSATPSLQSIL- 408
Cdd:pfam02463  182 TENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLyLDYLKLNEERIDLLQELLRDEQEEIESSKQEIe 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   409 -PPDLPSDDGALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSECGIE 487
Cdd:pfam02463  262 kEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   488 NLRRELELLKEENEKQAQEAQAEftrklaeksvevLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIREL 567
Cdd:pfam02463  342 KELKELEIKREAEEEEEEELEKL------------QEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   568 NQQLdevttqLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLV 647
Cdd:pfam02463  410 LLEL------ARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQ 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   648 REMTEnainQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKT----- 722
Cdd:pfam02463  484 EQLEL----LLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSatade 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   723 -LGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAES-------ESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHD 794
Cdd:pfam02463  560 vEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEidpilnlAQLDKATLEADEDDKRAKVVEGILKDTELTKLKE 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   795 EISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSScHTDVESKTKQLE 874
Cdd:pfam02463  640 SAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ-REKEELKKLKLE 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   875 AANAALEKVNKEYAESRAEASDLQDKVKEITDTlhaELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQK 954
Cdd:pfam02463  719 AEELLADRVQEAQDKINEELKLLKQKIDEEEEE---EEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEK 795

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   955 EKELQELRQQLQDsqdsqtKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEK 1034
Cdd:pfam02463  796 LKAQEEELRALEE------ELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1035 MASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFElfemeadmnsERLIEKVTGIKEELKETH 1114
Cdd:pfam02463  870 QELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEE----------RIKEEAEILLKYEEEPEE 939

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1115 LQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKL 1194
Cdd:pfam02463  940 LLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRL 1019

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|
gi 442628159  1195 NESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSG 1234
Cdd:pfam02463 1020 KEFLELFVSINKGWNKVFFYLELGGSAELRLEDPDDPFSG 1059
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1212-1452 1.23e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 65.17  E-value: 1.23e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1212 QDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLdaqQATNKELQELLVKSQEN 1291
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQEL---AALEAELAELEKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1292 EGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSK 1371
Cdd:COG4942    96 RAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1372 LAEQLSQLKQANEELQKSLQQKQLLLEKgneFDTQLAEYQKVIDEMDDAAsvksallEQLQNRVAELETALRQANDAQKT 1451
Cdd:COG4942   176 LEALLAELEEERAALEALKAERQKLLAR---LEKELAELAAELAELQQEA-------EELEALIARLEAEAAAAAERTPA 245


                  .
gi 442628159 1452 A 1452
Cdd:COG4942   246 A 246
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 1116-1391 1.31e-10

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 66.20  E-value: 1.31e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1116 QLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEK--LTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTK 1193
Cdd:pfam05667  215 ELAAAQEWEEEWNSQGLASRLTPEEYRKRKRTKLLKriAEQLRSAALAGTEATSGASRSAQDLAELLSSFSGSSTTDTGL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1194 LNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDA 1273
Cdd:pfam05667  295 TKGSRFTHTEKLQFTNEAPAATSSPPTKVETEEELQQQREEELEELQEQLEDLESSIQELEKEIKKLESSIKQVEEELEE 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1274 QQATNKELQE----------LLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQ-GKLDESNTVLE 1342
Cdd:pfam05667  375 LKEQNEELEKqykvkkktldLLPDAEENIAKLQALVDASAQRLVELAGQWEKHRVPLIEEYRALKEAKsNKEDESQRKLE 454

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442628159  1343 SQKKSHNEIQDKLEQAQQKE---RTLQEE-------------TSKLAEQLSQLKQANEELQKSLQ 1391
Cdd:pfam05667  455 EIKELREKIKEVAEEAKQKEelyKQLVAEyerlpkdvsrsayTRRILEIVKNIKKQKEEITKILS 519
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 306-854 1.78e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 65.81  E-value: 1.78e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   306 LREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQFCGDELN---AQSQV 382
Cdd:TIGR04523  129 LEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLElllSNLKK 208

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   383 YKEKIHDLESKITKLVSATPSLQSILPpDLPSDDGALQEEIAKLQEKMtIQQKEVESRIAEQLEEEQRLRENVKYLNEQI 462
Cdd:TIGR04523  209 KIQKNKSLESQISELKKQNNQLKDNIE-KKQQEINEKTTEISNTQTQL-NQLKDEQNKIKKQLSEKQKELEQNNKKIKEL 286

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   463 ATLQSELVSKDEALEKfsLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESE 542
Cdd:TIGR04523  287 EKQLNQLKSEISDLNN--QKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRE 364

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   543 RVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAK 622
Cdd:TIGR04523  365 LEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKD 444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   623 TLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTqkdf 702
Cdd:TIGR04523  445 LTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKIS---- 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   703 ELVESGESLKKLQQQLEQKTLGHE-KLQAALEELKKEK-ETIIKEKEQELQQL---QSKSAESESALKVVQVQLEQLQQQ 777
Cdd:TIGR04523  521 SLKEKIEKLESEKKEKESKISDLEdELNKDDFELKKENlEKEIDEKNKEIEELkqtQKSLKKKQEEKQELIDQKEKEKKD 600

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 442628159   778 AAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGE 854
Cdd:TIGR04523  601 LIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDD 677
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1142-1382 2.13e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 64.40  E-value: 2.13e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1142 QQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKK 1221
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1222 EKQLQEEAAKLSGELQQVQEANGDI----KDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLvksqenegnlqg 1297
Cdd:COG4942    99 LEAQKEELAELLRALYRLGRQPPLAlllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALR------------ 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1298 eslavteklQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLS 1377
Cdd:COG4942   167 ---------AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237


                  ....*
gi 442628159 1378 QLKQA 1382
Cdd:COG4942   238 AAAER 242
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 662-1394 2.15e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.91  E-value: 2.15e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   662 KESIEQQLALKQNELEDFQKKQSES-EVH-----------------LQEIKAQ-NTQKDFELVESgESLKKLQQQLEQKT 722
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESnELHekqkfylrqsvidlqtkLQEMQMErDAMADIRRRES-QSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   723 LGHEKLQAALEELKKEKETIIKE-------KEQELQQLQSKSAESESAL-KVVQVQLEQLQQQAAASGEEGSKTVAKLHD 794
Cdd:pfam15921  152 HELEAAKCLKEDMLEDSNTQIEQlrkmmlsHEGVLQEIRSILVDFEEASgKKIYEHDSMSTMHFRSLGSAISKILRELDT 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   795 EISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAkKSGHLLEqITKLKSEVGETQAALSSCHTDVESKTKQLE 874
Cdd:pfam15921  232 EISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQL-ISEHEVE-ITGLTEKASSARSQANSIQSQLEIIQEQAR 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   875 AANAAL--------EKVNKEYAESRAEASDLQDKVKEITDTL---HAELQAERS-------SSSALHTKLSKFSDEIATG 936
Cdd:pfam15921  310 NQNSMYmrqlsdleSTVSQLRSELREAKRMYEDKIEELEKQLvlaNSELTEARTerdqfsqESGNLDDQLQKLLADLHKR 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   937 HKELTSKADA----WSQEM---LQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQeevtkAKTENLELST 1009
Cdd:pfam15921  390 EKELSLEKEQnkrlWDRDTgnsITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ-----GKNESLEKVS 464

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1010 GTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVE----AIQVANANISATNAELSTVLEVLQAEKSETNHIf 1085
Cdd:pfam15921  465 SLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQekerAIEATNAEITKLRSRVDLKLQELQHLKNEGDHL- 543

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1086 elfemeadmnserliekvTGIKEELKETHLQLDERQKKFEELEEKLKQAQQ-------SEQKLQQESQTSKEKLTEIQQS 1158
Cdd:pfam15921  544 ------------------RNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgqhgrTAGAMQVEKAQLEKEINDRRLE 605

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1159 LQELQDSVKQKEELVQNLEEKVressSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQlqeEAAKLSGELQQ 1238
Cdd:pfam15921  606 LQEFKILKDKKDAKIRELEARV----SDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRN---ELNSLSEDYEV 678

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1239 VQEangDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQ-------ELLVKSQENEGNLQGESLAVTEKLQQLEQ 1311
Cdd:pfam15921  679 LKR---NFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEgsdghamKVAMGMQKQITAKRGQIDALQSKIQFLEE 755

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1312 ANGELKealcQKENGLKELQGKLDESNTVLESQKkshNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQ 1391
Cdd:pfam15921  756 AMTNAN----KEKHFLKEEKNKLSQELSTVATEK---NKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQ 828


                   ...
gi 442628159  1392 QKQ 1394
Cdd:pfam15921  829 RQE 831
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 739-1469 2.19e-10

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 65.97  E-value: 2.19e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   739 KETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQqqaaasgEEGSKTVAKLHDEiSQLKSQAEETQSELKSTQSNLE 818
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLC-------EEKNALQEQLQAE-TELCAEAEEMRARLAARKQELE 74

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   819 AKSKQLEAangSLEEEAKKSGHLL-------EQITKLKSEVGETQAALSSCHTD---VESKTKQLEAANAALEKVNKEYA 888
Cdd:pfam01576   75 EILHELES---RLEEEEERSQQLQnekkkmqQHIQDLEEQLDEEEAARQKLQLEkvtTEAKIKKLEEDILLLEDQNSKLS 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   889 EsraEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAwSQEMLQKEKELQELRQQLQDS 968
Cdd:pfam01576  152 K---ERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQEL-EKAKRKLEGESTDLQEQIAEL 227

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   969 QDSQTKLKAEGERKEKSFEESIKNLQEEvTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKT 1048
Cdd:pfam01576  228 QAQIAELRAQLAKKEEELQAALARLEEE-TAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKT 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1049 LVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELE 1128
Cdd:pfam01576  307 ELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESEN 386

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1129 EKLKQAQQSEQKLQQESQTSKEKLteiQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCL 1208
Cdd:pfam01576  387 AELQAELRTLQQAKQDSEHKRKKL---EGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDV 463

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1209 KETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKS 1288
Cdd:pfam01576  464 SSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEAL 543

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1289 QENEGNLQGESLAVTEKLQQLEQANGELkealcqkENGLKELQGKLDESNTVLESQKkshnEIQDKLEQAQQKERTLQEE 1368
Cdd:pfam01576  544 EEGKKRLQRELEALTQQLEEKAAAYDKL-------EKTKNRLQQELDDLLVDLDHQR----QLVSNLEKKQKKFDQMLAE 612

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1369 TSKLAEQLSQLKQANEELQKSLQQKQLLLEKgnefdtQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDA 1448
Cdd:pfam01576  613 EKAISARYAEERDRAEAEAREKETRALSLAR------ALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERS 686

                          730       740
                   ....*....|....*....|.
gi 442628159  1449 QKTAYLETKELRRQLESLELE 1469
Cdd:pfam01576  687 KRALEQQVEEMKTQLEELEDE 707
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
949-1513 2.25e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.47  E-value: 2.25e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  949 QEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEEsIKNLQEEVTKAKTENLELstgtQTTIKDLQERLEITNAE 1028
Cdd:PRK03918  200 KELEEVLREINEISSELPELREELEKLEKEVKELEELKEE-IEELEKELESLEGSKRKL----EEKIRELEERIEELKKE 274

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1029 LQHKEKMASE------DAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNhifelfemeadmNSERLIEK 1102
Cdd:PRK03918  275 IEELEEKVKElkelkeKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELE------------EKEERLEE 342

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1103 VTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESqtskekLTEIQQSLQELQDSVKQKEELVQNLEEKVRE 1182
Cdd:PRK03918  343 LKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLT------PEKLEKELEELEKAKEEIEEEISKITARIGE 416

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1183 SSSIIEAQNTKLNESNVQ-------------------LENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEAN 1243
Cdd:PRK03918  417 LKKEIKELKKAIEELKKAkgkcpvcgrelteehrkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELI 496

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1244 gdikdSLVKVEELVKVLEEKLQAAtsQLDAQQATNKELQELLVKSQENEGNLQGESLAVtEKLQQLEQANGELKEALCQK 1323
Cdd:PRK03918  497 -----KLKELAEQLKELEEKLKKY--NLEELEKKAEEYEKLKEKLIKLKGEIKSLKKEL-EKLEELKKKLAELEKKLDEL 568

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1324 ENGLKELQGKLDE----SNTVLESQ--------------KKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEE 1385
Cdd:PRK03918  569 EEELAELLKELEElgfeSVEELEERlkelepfyneylelKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKE 648

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1386 LQkslqqkqlllEKGNEFDTQlaEYQKVIDEMddaasvksallEQLQNRVAELETALRQANDAQKTAYLETKELRRQLES 1465
Cdd:PRK03918  649 LE----------ELEKKYSEE--EYEELREEY-----------LELSRELAGLRAELEELEKRREEIKKTLEKLKEELEE 705

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*...
gi 442628159 1466 LElEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSII 1513
Cdd:PRK03918  706 RE-KAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEI 752
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1305-1533 2.98e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 2.98e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1305 KLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLS----QLK 1380
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIArleeRRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1381 QANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELR 1460
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442628159 1461 RQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKNDALKAKVQTLETL 1533
Cdd:COG1196   393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 170-748 3.43e-10

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 64.71  E-value: 3.43e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  170 MAVGDRVIVSSGFGsrpgILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFV--------------- 234
Cdd:COG5244     4 LSVNDRVLLGDKFG----TVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIrpdddsllngnaaye 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  235 --------------PIAKVSLSPSSKKTRLSRTGSRESLTSIGTMNSIATTATSRMR--------MNAQQRKSSTPVKPI 292
Cdd:COG5244    80 kikgglvceskgmdKDGEIKQENHEDRIHFEESKIRRLEETIEALKSTEKEEIVELRreneeldkINLSLRERISSEEPE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  293 LATPKSQFSMQDL--LREKQQHVEKLMVERDLDREDAQNQALQLQKNI--NELKARIVE--------LESALDNERKKTE 360
Cdd:COG5244   160 LNKDGSKLSYDELkeFVEESRVQVYDMVELVSDISETLNRNGSIQRSSvrECERSNIHDvlflvngiLDGVIDELNGELE 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  361 ELQ---CSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLvsATPSLQSILPPDLPSDDGALQEEIAKLQEKMTIQQkeV 437
Cdd:COG5244   240 RLRrqlVSLMSSHGIEVEENSRLKATLEKFQSLELKVNTL--QEELYQNKLLKKFYQIYEPFAQAALSSQLQYLAEV--I 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  438 ESRIAEQLEeeqrlrenvkylNEQIATLQSELVSKDEALEKFSLSECgiENLRRELELLKEENEKQAQEAQAEFTRKLAE 517
Cdd:COG5244   316 ESENFGKLE------------NIEIHIILKVLSSISYALHIYTIKNT--PDHLETTLQCFVNIAPISMWLSEFLQRKFSS 381

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  518 KSVEVLrlsSELQNLKATSDSLE----------------------SERVNKTDECEILQTEVRMRdeQIRELNQQlDEVT 575
Cdd:COG5244   382 KQETAF---SICQFLEDNKDVTLilkilhpilettvpkllaflrtNSNFNDNDTLCLIGSLYEIA--RIDKLIGK-EEIS 455

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  576 TQLN----VQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMT 651
Cdd:COG5244   456 KQDNrlflYPSCDITLSSILTILFSDKLEVFFQGIESLLENITIFPEQPSQQTSDSENIKENSLLSDRLNEENIRLKEVL 535

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  652 ENAINQIQLEKESieQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHE---KL 728
Cdd:COG5244   536 VQKENMLTEETKI--KIIIGRDLERKTLEENIKTLKVELNNKNNKLKEENFNLVNRLKNMELKLYQIKDNNTLNKiylDL 613

                         650       660
                  ....*....|....*....|
gi 442628159  729 QAALEELKKEKETIIKEKEQ 748
Cdd:COG5244   614 VSEIMELRETIRRQIKEQKR 633
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1108-1320 4.49e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 63.63  E-value: 4.49e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1108 EELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSII 1187
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1188 EAQNTKLNESNVQLENKTsclKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAA 1267
Cdd:COG4942   100 EAQKEELAELLRALYRLG---RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 442628159 1268 TSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEAL 1320
Cdd:COG4942   177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALI 229
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1099-1467 6.66e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.32  E-value: 6.66e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1099 LIEKVTGIKE---ELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTsKEKLTEIQQSLQELQDSVKQKEElvqn 1175
Cdd:TIGR02169  158 IIDEIAGVAEfdrKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREK-AERYQALLKEKREYEGYELLKEK---- 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1176 leEKVRESSSIIEAQNTKLNESNVQLEnktsclKETQDQLLESQKKEKQLQEEAAKL----SGELQQVQEANGDIKDSLV 1251
Cdd:TIGR02169  233 --EALERQKEAIERQLASLEEELEKLT------EEISELEKRLEEIEQLLEELNKKIkdlgEEEQLRVKEKIGELEAEIA 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1252 KVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQ 1331
Cdd:TIGR02169  305 SLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1332 GKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGnefDTQLAEYQ 1411
Cdd:TIGR02169  385 DELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ---EWKLEQLA 461

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 442628159  1412 KVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLE 1467
Cdd:TIGR02169  462 ADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLK 517
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
448-1003 6.91e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 63.93  E-value: 6.91e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  448 EQRLRENVKYLNEQIatlqselvskdEALEKFSLSECGIENLRRELELLKEENEKQAQeaqaEFTRKLAEKSVEVLRLSS 527
Cdd:PRK03918  164 YKNLGEVIKEIKRRI-----------ERLEKFIKRTENIEELIKEKEKELEEVLREIN----EISSELPELREELEKLEK 228

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  528 ELQNLKATSDSLESERVnktdECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDmLRLQKEGTEEKSTLLE 607
Cdd:PRK03918  229 EVKELEELKEEIEELEK----ELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKE-LKEKAEEYIKLSEFYE 303

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  608 KTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIE--QQLALKQNELEDFQKKQSE 685
Cdd:PRK03918  304 EYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHElyEEAKAKKEELERLKKRLTG 383

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  686 SEVHLQEIKAQNTQKDFELVEsgESLKKLQQQLEQKTLGHEKLQAALEELKK---------------EKETIIKEKEQEL 750
Cdd:PRK03918  384 LTPEKLEKELEELEKAKEEIE--EEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelteeHRKELLEEYTAEL 461

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  751 QQLQSKSAESESALKVVQVQLEQLQQQAaasgeEGSKTVAKLHDEISQLKSQAEETQS--------------ELKSTQSN 816
Cdd:PRK03918  462 KRIEKELKEIEEKERKLRKELRELEKVL-----KKESELIKLKELAEQLKELEEKLKKynleelekkaeeyeKLKEKLIK 536

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  817 LEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALS----SCHTDVESKTKQLEAANA---ALEKVNKEYAE 889
Cdd:PRK03918  537 LKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEelgfESVEELEERLKELEPFYNeylELKDAEKELER 616

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  890 SRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEiatGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQ 969
Cdd:PRK03918  617 EEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEE---EYEELREEYLELSRELAGLRAELEELEKRREEIK 693

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|...
gi 442628159  970 DSQTKLKAEGERKEKSFEES---------IKNLQEEVTKAKTE 1003
Cdd:PRK03918  694 KTLEKLKEELEEREKAKKELeklekalerVEELREKVKKYKAL 736
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 301-1026 9.62e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 63.50  E-value: 9.62e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   301 SMQDLLREKQQHVEKLMVERDLDREDAQNqalqLQKNINELKARIVELESALDNERKKTEELQCSIdeaqfcgDELNAQS 380
Cdd:TIGR04523   44 TIKNELKNKEKELKNLDKNLNKDEEKINN----SNNKIKILEQQIKDLNDKLKKNKDKINKLNSDL-------SKINSEI 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   381 QVYKEKIHDLESKITKLvsatpslqsilppdlpsddgalqeeiaklqEKmtiQQKEVESRIAEQLEEEQRLRENVKYLNE 460
Cdd:TIGR04523  113 KNDKEQKNKLEVELNKL------------------------------EK---QKKENKKNIDKFLTEIKKKEKELEKLNN 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   461 QIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKqaqeaqaeFTRKLAEKSVEVLRLSSELQNLKATSDSLE 540
Cdd:TIGR04523  160 KYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLEL--------LLSNLKKKIQKNKSLESQISELKKQNNQLK 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   541 SERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLN-----VQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQ 615
Cdd:TIGR04523  232 DNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSekqkeLEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKE 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   616 SKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKkqsESEVHLQEIKA 695
Cdd:TIGR04523  312 LKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKK---ENQSYKQEIKN 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   696 QNTQKdfelvesgeslKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEkEQELQQLQSKSAESESALKVVQVQLEqlq 775
Cdd:TIGR04523  389 LESQI-----------NDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE-IERLKETIIKNNSEIKDLTNQDSVKE--- 453

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   776 qqaaasgeegsKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGE- 854
Cdd:TIGR04523  454 -----------LIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSl 522

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   855 --TQAALSSCHTDVESKTKQLEAanaalEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDE 932
Cdd:TIGR04523  523 keKIEKLESEKKEKESKISDLED-----ELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKE 597

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   933 IatghKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAegerKEKSFEESIKNLQEEVTKAKTENLELSTGTQ 1012
Cdd:TIGR04523  598 K----KDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKS----KKNKLKQEVKQIKETIKEIRNKWPEIIKKIK 669

                          730
                   ....*....|....
gi 442628159  1013 TTIKDLQERLEITN 1026
Cdd:TIGR04523  670 ESKTKIDDIIELMK 683
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
315-935 1.30e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 63.14  E-value: 1.30e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  315 KLMVERDLDreDAQNQALQLQKNINE-----LKARIVELESALDNERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIHD 389
Cdd:PRK02224  175 RLGVERVLS--DQRGSLDQLKAQIEEkeekdLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREE 252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  390 LESkitklvsatpslqsilppdlpsddgaLQEEIAKLQEKmtiqqkevesrIAEQLEEEQRLRENVKYLNEQIATLQSEL 469
Cdd:PRK02224  253 LET--------------------------LEAEIEDLRET-----------IAETEREREELAEEVRDLRERLEELEEER 295

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  470 vskDEALEKFSLSECGIEnlrrelelLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDE 549
Cdd:PRK02224  296 ---DDLLAEAGLDDADAE--------AVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREE 364

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  550 CEILQTE-------VRMRDEQIRELNQQLDEVTTQLN---VQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQ 619
Cdd:PRK02224  365 AAELESEleeareaVEDRREEIEELEEEIEELRERFGdapVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE 444

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  620 AAKTLNdkeqlEKQISDLKQLAEQEKLVREMTENainqiqlekesiEQQLALKQNELEDFQKKQSESEvhlqeikaqntq 699
Cdd:PRK02224  445 AEALLE-----AGKCPECGQPVEGSPHVETIEED------------RERVEELEAELEDLEEEVEEVE------------ 495

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  700 kdfELVESGESLKKLQQQLEQKtlghEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAlkvvQVQLEQLQQQAA 779
Cdd:PRK02224  496 ---ERLERAEDLVEAEDRIERL----EERREDLEELIAERRETIEEKRERAEELRERAAELEAE----AEEKREAAAEAE 564

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  780 ASGEEGSKTVAKLHDEISQLKSQAE------ETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVG 853
Cdd:PRK02224  565 EEAEEAREEVAELNSKLAELKERIEslerirTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFD 644

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  854 ETQaalsschtdVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLH--AELQAERSSSSALHTKLSKFSD 931
Cdd:PRK02224  645 EAR---------IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEelEELRERREALENRVEALEALYD 715


                  ....
gi 442628159  932 EIAT 935
Cdd:PRK02224  716 EAEE 719
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 1087-1398 1.82e-09

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 62.16  E-value: 1.82e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1087 LFEMEADMNSERLIEkvtgIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSV 1166
Cdd:PRK04778   88 LFEAEELNDKFRFRK----AKHEINEIESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYRELRKSLLANRFSF 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1167 --------KQKEELVQNLEEKVRESSS--IIEAQNT--KLNESNVQLENKT--------SCLKETQDQLLESQKKEKQLQ 1226
Cdd:PRK04778  164 gpaldeleKQLENLEEEFSQFVELTESgdYVEAREIldQLEEELAALEQIMeeipellkELQTELPDQLQELKAGYRELV 243

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1227 EE-----AAKLSGELQQVQEAngdIKDSLVKVEEL-VKVLEEKLQAATSQLD-----------AQQ---ATNKELQELLV 1286
Cdd:PRK04778  244 EEgyhldHLDIEKEIQDLKEQ---IDENLALLEELdLDEAEEKNEEIQERIDqlydilerevkARKyveKNSDTLPDFLE 320

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1287 KSQENEGNLQGEslavTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQ 1366
Cdd:PRK04778  321 HAKEQNKELKEE----IDRVKQSYTLNESELESVRQLEKQLESLEKQYDEITERIAEQEIAYSELQEELEEILKQLEEIE 396

                         330       340       350
                  ....*....|....*....|....*....|..
gi 442628159 1367 EETSKLAEQLSQLKQANEELQKSLQQKQLLLE 1398
Cdd:PRK04778  397 KEQEKLSEMLQGLRKDELEAREKLERYRNKLH 428
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
895-1533 2.21e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 62.36  E-value: 2.21e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  895 SDLQDKVKEITDT-LHAELQAERSSSSALHTKLSKFSDEIATGhKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSqt 973
Cdd:PRK02224  190 DQLKAQIEEKEEKdLHERLNGLESELAELDEEIERYEEQREQA-RETRDEADEVLEEHEERREELETLEAEIEDLRET-- 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  974 klKAEGERKEKSFEESIKNLQEEVTKAKTEN------LELSTGTQTTIKDLQERLEITNAELQhkekmasedaqkiadlk 1047
Cdd:PRK02224  267 --IAETEREREELAEEVRDLRERLEELEEERddllaeAGLDDADAEAVEARREELEDRDEELR----------------- 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1048 tlvEAIQVANANISATNAELSTVLEvlQAEKSETNhifelfemeadmnSERLIEKVTGIKEELKETHLQLDERQKKFEEL 1127
Cdd:PRK02224  328 ---DRLEECRVAAQAHNEEAESLRE--DADDLEER-------------AEELREEAAELESELEEAREAVEDRREEIEEL 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1128 EEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSC 1207
Cdd:PRK02224  390 EEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVET 469

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1208 LKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEangdikdsLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVK 1287
Cdd:PRK02224  470 IEEDRERVEELEAELEDLEEEVEEVEERLERAED--------LVEAEDRIERLEERREDLEELIAERRETIEEKRERAEE 541

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1288 SQENEGNLQGESLAVTEKLQQLEQANGELKEALcqkenglKELQGKLDESNTVLESQkkshNEIQDKLEQAQQKERTLQE 1367
Cdd:PRK02224  542 LRERAAELEAEAEEKREAAAEAEEEAEEAREEV-------AELNSKLAELKERIESL----ERIRTLLAAIADAEDEIER 610

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1368 etskLAEQLSQLKQANEELQKSLQQKqlllekgNEFDTQLAEyqkvidEMDDAAsvksalLEQLQNRVAELETALRQAND 1447
Cdd:PRK02224  611 ----LREKREALAELNDERRERLAEK-------RERKRELEA------EFDEAR------IEEAREDKERAEEYLEQVEE 667

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1448 aqktaylETKELRRQLESLEleksrevlslkAQMNGASSrsgkgdEVESLDietslakinflnsiiaDMQQKNDALKAKV 1527
Cdd:PRK02224  668 -------KLDELREERDDLQ-----------AEIGAVEN------ELEELE----------------ELRERREALENRV 707


                  ....*.
gi 442628159 1528 QTLETL 1533
Cdd:PRK02224  708 EALEAL 713
PTZ00121 PTZ00121
MAEBL; Provisional
 355-957 2.25e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.85  E-value: 2.25e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  355 ERKKTEELQCSIDEAQfCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSilPPDLPSDDGALQEEIAKLQEKMTIQQ 434
Cdd:PTZ00121 1300 EKKKADEAKKKAEEAK-KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKA--EAEAAADEAEAAEEKAEAAEKKKEEA 1376

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  435 KEvESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSEcgienLRRELELLKEENEKQAQEA-QAEFTR 513
Cdd:PTZ00121 1377 KK-KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAK-----KKAEEKKKADEAKKKAEEAkKADEAK 1450

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  514 KLAE--KSVEVLRLSSElQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIR---ELNQQLDEVTTQLNVQKADSSAL 588
Cdd:PTZ00121 1451 KKAEeaKKAEEAKKKAE-EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKkaaEAKKKADEAKKAEEAKKADEAKK 1529

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  589 DDMLRLQKEG--TEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIE 666
Cdd:PTZ00121 1530 AEEAKKADEAkkAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  667 QQLalKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQqqlEQKTLGHEKLQAALEELKKEKETIIKEK 746
Cdd:PTZ00121 1610 EEA--KKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAE---EENKIKAAEEAKKAEEDKKKAEEAKKAE 1684

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  747 EQELQQLQSKSAESESALKVVQVQLEQLQQQAAasGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKqleA 826
Cdd:PTZ00121 1685 EDEKKAAEALKKEAEEAKKAEELKKKEAEEKKK--AEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKK---I 1759

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  827 ANGSLEEEAKKSGHLLEQITKLKSEVGETQaalSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQD-KVKEIT 905
Cdd:PTZ00121 1760 AHLKKEEEKKAEEIRKEKEAVIEEELDEED---EKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDsAIKEVA 1836

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|..
gi 442628159  906 DTlhAELQAERSSSSALHtKLSKFSDEIATGHKELTSKADAWSQEMLQKEKE 957
Cdd:PTZ00121 1837 DS--KNMQLEEADAFEKH-KFNKNNENGEDGNKEADFNKEKDLKEDDEEEIE 1885
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1145-1388 2.28e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 61.32  E-value: 2.28e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1145 SQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLenktsclKETQDQLLESQKKEKQ 1224
Cdd:COG4942    15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRI-------RALEQELAALEAELAE 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1225 LQEEAAKLSGELQQVQEANGDIKDSLVKVEElvkvlEEKLQAATSQLDAQQA-TNKELQELLVKSQENEGNlqgeslAVT 1303
Cdd:COG4942    88 LEKEIAELRAELEAQKEELAELLRALYRLGR-----QPPLALLLSPEDFLDAvRRLQYLKYLAPARREQAE------ELR 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1304 EKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQAN 1383
Cdd:COG4942   157 ADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236


                  ....*
gi 442628159 1384 EELQK 1388
Cdd:COG4942   237 AAAAE 241
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 1130-1460 2.92e-09

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 61.78  E-value: 2.92e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1130 KLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKtscLK 1209
Cdd:PRK04778   99 RFRKAKHEINEIESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYRELRKSLLANRFSFGPALDELEKQ---LE 175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1210 ETQDQLlesqKKEKQLQEEA--AKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAatsQLDAQQATNKELQEllvk 1287
Cdd:PRK04778  176 NLEEEF----SQFVELTESGdyVEAREILDQLEEELAALEQIMEEIPELLKELQTELPD---QLQELKAGYRELVE---- 244

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1288 sqEN----EGNLQGESLAVTEKLQQLEQ--ANGELKEAlcqkENGLKELQGKLDESNTVLESQKKSHNEIQDKLEqaqqk 1361
Cdd:PRK04778  245 --EGyhldHLDIEKEIQDLKEQIDENLAllEELDLDEA----EEKNEEIQERIDQLYDILEREVKARKYVEKNSD----- 313

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1362 erTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETA 1441
Cdd:PRK04778  314 --TLPDFLEHAKEQNKELKEEIDRVKQSYTLNESELESVRQLEKQLESLEKQYDEITERIAEQEIAYSELQEELEEILKQ 391

                         330
                  ....*....|....*....
gi 442628159 1442 LRQANDAQKTAYLETKELR 1460
Cdd:PRK04778  392 LEEIEKEQEKLSEMLQGLR 410
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 307-1205 3.69e-09

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 61.99  E-value: 3.69e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   307 REKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQcSIDEAQFCGDELNAQsqvykek 386
Cdd:TIGR00606  216 KEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIK-ALKSRKKQMEKDNSE------- 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   387 ihdLESKITKLVSATPSLQSILPPDLPSDDGALQEEIAKLQ---EKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIA 463
Cdd:TIGR00606  288 ---LELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQrelEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIR 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   464 TLQSELVSKD-----EALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATsds 538
Cdd:TIGR00606  365 ARDSLIQSLAtrlelDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRT--- 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   539 LESERVNKTDECEILQtEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTE--KELVQS 616
Cdd:TIGR00606  442 IELKKEILEKKQEELK-FVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADldRKLRKL 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   617 KEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLE------KESIEQQLALKQNELEDFQKKQSESEVHL 690
Cdd:TIGR00606  521 DQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgyfpnKKQLEDWLHSKSKEINQTRDRLAKLNKEL 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   691 QEIKAQNTQKDFELVESGESLKKLQQQLEQkTLGHEKLQAALEELKKEketiIKEKEQELQQLQSKSAESESALKVVQVQ 770
Cdd:TIGR00606  601 ASLEQNKNHINNELESKEEQLSSYEDKLFD-VCGSQDEESDLERLKEE----IEKSSKQRAMLAGATAVYSQFITQLTDE 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   771 LEQLQQQAaasgEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKS 850
Cdd:TIGR00606  676 NQSCCPVC----QRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRN 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   851 EVGETQAALSSCHTDVESKTKQLEAANAAlEKVNKEYAESRAEASDLQDKVKEITDTLhaELQAERSSSSALHTKLSKFS 930
Cdd:TIGR00606  752 KLQKVNRDIQRLKNDIEEQETLLGTIMPE-EESAKVCLTDVTIMERFQMELKDVERKI--AQQAAKLQGSDLDRTVQQVN 828

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   931 DEIATGHKEL---TSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERK---EKSFEESIKNLQEEVTKAKTEN 1004
Cdd:TIGR00606  829 QEKQEKQHELdtvVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRqqfEEQLVELSTEVQSLIREIKDAK 908

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1005 LELSTGTQTTIKDLQERLEITNAELQHKEK-------MASEDAQKIADLKTLVEAIQVANANisaTNAELSTVLEVLQAE 1077
Cdd:TIGR00606  909 EQDSPLETFLEKDQQEKEELISSKETSNKKaqdkvndIKEKVKNIHGYMKDIENKIQDGKDD---YLKQKETELNTVNAQ 985

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1078 KSETNHIFELFemEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLK------------QAQQSEQKLQQES 1145
Cdd:TIGR00606  986 LEECEKHQEKI--NEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKqhlkemgqmqvlQMKQEHQKLEENI 1063

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442628159  1146 QTSKEKLTEIQQSLQELQDSVKQ-----KEELVQNLEEKVREssSIIEAQNTKLNESNVQLENKT 1205
Cdd:TIGR00606 1064 DLIKRNHVLALGRQKGYEKEIKHfkkelREPQFRDAEEKYRE--MMIVMRTTELVNKDLDIYYKT 1126
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1294-1533 9.76e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.34  E-value: 9.76e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1294 NLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLA 1373
Cdd:COG1196   236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1374 EQLSQLKQANEELQKSLQQKQLLLEkgnEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAY 1453
Cdd:COG1196   316 ERLEELEEELAELEEELEELEEELE---ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1454 LETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKNDALKAKVQTLETL 1533
Cdd:COG1196   393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1097-1532 9.89e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 60.31  E-value: 9.89e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1097 ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQS--------EQKLQQESQTSKEKLTEIQQSLQELQdsvkq 1168
Cdd:COG4913   291 ELLEAELEELRAELARLEAELERLEARLDALREELDELEAQirgnggdrLEQLEREIERLERELEERERRRARLE----- 365

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1169 keELVQNLEEKVRESSSIIEAQNTKLNEsnvQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQ---------- 1238
Cdd:COG4913   366 --ALLAALGLPLPASAEEFAALRAEAAA---LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASlerrksnipa 440

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1239 -VQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKEL----QELLVKSQ------------ENEGNLQGESLA 1301
Cdd:COG4913   441 rLLALRDALAEALGLDEAELPFVGELIEVRPEEERWRGAIERVLggfaLTLLVPPEhyaaalrwvnrlHLRGRLVYERVR 520

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1302 VTEKLQQLEQAN-GELKEALCQKENGLKE-LQGKLDESNTV--------------------LESQKKSHNEIQD------ 1353
Cdd:COG4913   521 TGLPDPERPRLDpDSLAGKLDFKPHPFRAwLEAELGRRFDYvcvdspeelrrhpraitragQVKGNGTRHEKDDrrrirs 600

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1354 ----------KLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEF------DTQLAEYQKVIDEM 1417
Cdd:COG4913   601 ryvlgfdnraKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEidvasaEREIAELEAELERL 680

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1418 DDAasvkSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLEleksREVLSLKAQMNGASSRsgkGDEVESL 1497
Cdd:COG4913   681 DAS----SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAE----EELDELQDRLEAAEDL---ARLELRA 749

                         490       500       510
                  ....*....|....*....|....*....|....*...
gi 442628159 1498 DIETSLAKI---NFLNSIIADMQQKNDALKAKVQTLET 1532
Cdd:COG4913   750 LLEERFAAAlgdAVERELRENLEERIDALRARLNRAEE 787
PTZ00121 PTZ00121
MAEBL; Provisional
 982-1474 1.03e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.54  E-value: 1.03e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  982 KEKSFEESIKNLQEEVTKAKTENLELSTGTQTTikdlqerlEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANIS 1061
Cdd:PTZ00121 1077 KDFDFDAKEDNRADEATEEAFGKAEEAKKTETG--------KAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA 1148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1062 ATNAELSTVLEVLQAEKSEtnhIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEElEEKLKQAQQSEQKL 1141
Cdd:PTZ00121 1149 EDAKRVEIARKAEDARKAE---EARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEE-ERKAEEARKAEDAK 1224

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1142 QQESQtskEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKK 1221
Cdd:PTZ00121 1225 KAEAV---KKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEK 1301

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1222 EKQlqEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLA 1301
Cdd:PTZ00121 1302 KKA--DEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKK 1379

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1302 VTEKLQQLEQANG--ELKEALCQKENGLKELQGKLDESNTVLESQKKShnEIQDKLEQAQQK--ERTLQEETSKLAEQ-- 1375
Cdd:PTZ00121 1380 ADAAKKKAEEKKKadEAKKKAEEDKKKADELKKAAAAKKKADEAKKKA--EEKKKADEAKKKaeEAKKADEAKKKAEEak 1457

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1376 -LSQLKQANEELQKS--LQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTA 1452
Cdd:PTZ00121 1458 kAEEAKKKAEEAKKAdeAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKAD 1537

                         490       500
                  ....*....|....*....|..
gi 442628159 1453 YLETKELRRQLEslELEKSREV 1474
Cdd:PTZ00121 1538 EAKKAEEKKKAD--ELKKAEEL 1557
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 809-1416 1.06e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 60.03  E-value: 1.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   809 ELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYA 888
Cdd:TIGR04523   41 KLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKN 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   889 ESRAEASDLQDKVKEiTDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDS 968
Cdd:TIGR04523  121 KLEVELNKLEKQKKE-NKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKL 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   969 QDSQTKLKaegerkekSFEESIKNLQEEVTKAKTENLELstgtQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKT 1048
Cdd:TIGR04523  200 ELLLSNLK--------KKIQKNKSLESQISELKKQNNQL----KDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1049 LVEAIQVANANISATNAELSTVLEVLQAEKSETNHifelfEMEADMNSErLIEKVTGIKEELKETHLQLDERQKKFEELE 1128
Cdd:TIGR04523  268 QLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNN-----QKEQDWNKE-LKSELKNQEKKLEEIQNQISQNNKIISQLN 341

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1129 EKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTS-- 1206
Cdd:TIGR04523  342 EQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQek 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1207 CLKETQDQLLESQKKE-----KQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKEL 1281
Cdd:TIGR04523  422 ELLEKEIERLKETIIKnnseiKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKL 501

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1282 QELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLK----------------ELQGKLDESNTVLESQK 1345
Cdd:TIGR04523  502 NEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNkddfelkkenlekeidEKNKEIEELKQTQKSLK 581

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442628159  1346 KSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQ----ANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE 1416
Cdd:TIGR04523  582 KKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKelekAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
HOOK pfam05622
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ...
 1108-1444 1.17e-08

HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.


Pssm-ID: 461694 [Multi-domain]  Cd Length: 528  Bit Score: 59.70  E-value: 1.17e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1108 EELKETHLQL----DERQKKFEELEEKLKQAQQSEQKLQ---QESQTSKEKLTEIQQS------LQELQDSVKQKEELVQ 1174
Cdd:pfam05622   69 EQLQEENFRLetarDDYRIKCEELEKEVLELQHRNEELTslaEEAQALKDEMDILRESsdkvkkLEATVETYKKKLEDLG 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1175 NLEEKVR--ESSSIIEAQNT--------KLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEAng 1244
Cdd:pfam05622  149 DLRRQVKllEERNAEYMQRTlqleeelkKANALRGQLETYKRQVQELHGKLSEESKKADKLEFEYKKLEEKLEALQKE-- 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1245 diKDSLVKVEELVKVLEEKLQAAtsqlDAQQATNKELQELLVKSQENEGNLQGE--SLAVTEKLQQLEQANGELKealCQ 1322
Cdd:pfam05622  227 --KERLIIERDTLRETNEELRCA----QLQQAELSQADALLSPSSDPGDNLAAEimPAEIREKLIRLQHENKMLR---LG 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1323 KEnglkelqgkldesntvlESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNE 1402
Cdd:pfam05622  298 QE-----------------GSYRERLTELQQLLEDANRRKNELETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSL 360

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 442628159  1403 FDTQLAEYQKVIDEMDDAASVKSALLEQLQN--------RVAELETALRQ 1444
Cdd:pfam05622  361 LKQKLEEHLEKLHEAQSELQKKKEQIEELEPkqdsnlaqKIDELQEALRK 410
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 595-828 1.80e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.62  E-value: 1.80e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  595 QKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDL-KQLAEQEKLVREmTENAINQIQLEKESIEQQLALKQ 673
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALeRRIAALARRIRA-LEQELAALEAELAELEKEIAELR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  674 NELEDFQKKQSESEVHLQEIKAQNT------QKDFELVESG--------ESLKKLQQQLEQKTLGHEKLQAALEELKKEK 739
Cdd:COG4942    97 AELEAQKEELAELLRALYRLGRQPPlalllsPEDFLDAVRRlqylkylaPARREQAEELRADLAELAALRAELEAERAEL 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  740 ETIIKEKEQELQQLQSKSAESESALKVVqvqleqlqqqaaasgeegSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEA 819
Cdd:COG4942   177 EALLAELEEERAALEALKAERQKLLARL------------------EKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                  ....*....
gi 442628159  820 KSKQLEAAN 828
Cdd:COG4942   239 AAERTPAAG 247
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
322-926 2.12e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.16  E-value: 2.12e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  322 LDREDAQNQALQLQKNINELKarivELESALDNERKKTEELQcsideaqfcgdELNAQSQVYKEKIHDLEsKITKLVSAT 401
Cdd:COG4913   218 LEEPDTFEAADALVEHFDDLE----RAHEALEDAREQIELLE-----------PIRELAERYAAARERLA-ELEYLRAAL 281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  402 PSLQSILppdlpsDDGALQEEIAKLQE---KMTIQQKEVESRIAEQLEEEQRLRENVKYL-NEQIATLQSELVSKDEALE 477
Cdd:COG4913   282 RLWFAQR------RLELLEAELEELRAelaRLEAELERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELE 355

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  478 KfslsecgienlrreleLLKEENEKQAQEAQAEFTRKLAEKSVEVLRlsselQNLKATSDSLESERvnktdecEILQTEV 557
Cdd:COG4913   356 E----------------RERRRARLEALLAALGLPLPASAEEFAALR-----AEAAALLEALEEEL-------EALEEAL 407

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  558 RMRDEQIRELNQQLDEVTTQLNVQKADSSALD-DMLRLQKEGTEEkstlLEKTEK------ELVQSKEQAAKTLNDKEQL 630
Cdd:COG4913   408 AEAEAALRDLRRELRELEAEIASLERRKSNIPaRLLALRDALAEA----LGLDEAelpfvgELIEVRPEEERWRGAIERV 483

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  631 -----------EKQISDLKQLAEQEKL--------VREMTENAINQiQLEKESIEQQLALKQNELEDFqkkqsesevhLQ 691
Cdd:COG4913   484 lggfaltllvpPEHYAAALRWVNRLHLrgrlvyerVRTGLPDPERP-RLDPDSLAGKLDFKPHPFRAW----------LE 552

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  692 EIKAQntQKDFELVESGESLKKLQQ------QLEQKTLGHEK---------------LQAALEELKKEketiIKEKEQEL 750
Cdd:COG4913   553 AELGR--RFDYVCVDSPEELRRHPRaitragQVKGNGTRHEKddrrrirsryvlgfdNRAKLAALEAE----LAELEEEL 626

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  751 QQLQSKSAESESALKVVQVQLEQLQQQAAASGEEgsKTVAKLHDEISQLksqaEETQSELKSTQSNLEAKSKQLEAANGS 830
Cdd:COG4913   627 AEAEERLEALEAELDALQERREALQRLAEYSWDE--IDVASAEREIAEL----EAELERLDASSDDLAALEEQLEELEAE 700

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  831 LEEeakksghLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHA 910
Cdd:COG4913   701 LEE-------LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEE 773

                         650
                  ....*....|....*.
gi 442628159  911 ELQAERSSSSALHTKL 926
Cdd:COG4913   774 RIDALRARLNRAEEEL 789
mukB PRK04863
chromosome partition protein MukB;
601-1467 2.21e-08

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 59.20  E-value: 2.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  601 EKSTLLEKTEKELVQSKEQAAKTLN-------DKEQLEKQISDLK----QLAEQEKLV------REMTENAINQIQLEKE 663
Cdd:PRK04863  314 RELAELNEAESDLEQDYQAASDHLNlvqtalrQQEKIERYQADLEeleeRLEEQNEVVeeadeqQEENEARAEAAEEEVD 393

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  664 SIEQQLALKQNELEDFQKKQSESEvhlQEIKAqntqkdfelvesgesLKKLQQQLEQKTLGHEKLQAALEELKKEKetii 743
Cdd:PRK04863  394 ELKSQLADYQQALDVQQTRAIQYQ---QAVQA---------------LERAKQLCGLPDLTADNAEDWLEEFQAKE---- 451

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  744 KEKEQELQQLQSKSAESESALKVVqvqleqlqqqaaasgEEGSKTVAKLHDEISqlKSQAEETQSELKSTQSNLEAKSKQ 823
Cdd:PRK04863  452 QEATEELLSLEQKLSVAQAAHSQF---------------EQAYQLVRKIAGEVS--RSEAWDVARELLRRLREQRHLAEQ 514

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  824 LEAANGSLEEeAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAAnaaLEKVNKEYAESRAEASDLQDKVKE 903
Cdd:PRK04863  515 LQQLRMRLSE-LEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEAR---LESLSESVSEARERRMALRQQLEQ 590

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  904 ItDTLHAELQAERSSSSALHTKLSKFSDEiaTGHKELTSKA-DAWSQEMLQKEKELQELRQqlqdsqdsqtklkaEGERK 982
Cdd:PRK04863  591 L-QARIQRLAARAPAWLAAQDALARLREQ--SGEEFEDSQDvTEYMQQLLERERELTVERD--------------ELAAR 653

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  983 EKSFEESIKNLQEEvtkaktenlelSTGTQTTIKDLQERLE-ITNAELQhkEKMASEDAQKI-ADLKTLVEAIQVAnani 1060
Cdd:PRK04863  654 KQALDEEIERLSQP-----------GGSEDPRLNALAERFGgVLLSEIY--DDVSLEDAPYFsALYGPARHAIVVP---- 716

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1061 satnaELSTVLEVLQAEKSETNhifELFEMEADMNSerLIEKVTGIKEELKETHLQLDERQ---KKFEEL--------EE 1129
Cdd:PRK04863  717 -----DLSDAAEQLAGLEDCPE---DLYLIEGDPDS--FDDSVFSVEELEKAVVVKIADRQwrySRFPEVplfgraarEK 786

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1130 KLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQK---------EELVQNLEEKVREsssiIEAQNTKLNESNVQ 1200
Cdd:PRK04863  787 RIEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFIGSHlavafeadpEAELRQLNRRRVE----LERALADHESQEQQ 862

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1201 LENKTSCLKETQDQL--LESQKK---EKQLQEEAAKLSGELQQVQEANGDIK---DSLVKVEELVKVLEEKlQAATSQLD 1272
Cdd:PRK04863  863 QRSQLEQAKEGLSALnrLLPRLNllaDETLADRVEEIREQLDEAEEAKRFVQqhgNALAQLEPIVSVLQSD-PEQFEQLK 941

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1273 AQQATNKELQEllvksqenegNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELqgkldesntvlesqkkshneIQ 1352
Cdd:PRK04863  942 QDYQQAQQTQR----------DAKQQAFALTEVVQRRAHFSYEDAAEMLAKNSDLNEK--------------------LR 991

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1353 DKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQlllekgnefdTQLAEYQKVIDEMDDAASvkSALLEQLQ 1432
Cdd:PRK04863  992 QRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKR----------QMLQELKQELQDLGVPAD--SGAEERAR 1059

                         890       900       910       920
                  ....*....|....*....|....*....|....*....|...
gi 442628159 1433 NRVAELETALRqANDAQKTAY--------LETKELRRQLESLE 1467
Cdd:PRK04863 1060 ARRDELHARLS-ANRSRRNQLekqltfceAEMDNLTKKLRKLE 1101
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 946-1524 2.30e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.21  E-value: 2.30e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   946 AWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEIT 1025
Cdd:pfam02463  163 AGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1026 NAEL---QHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEK 1102
Cdd:pfam02463  243 QELLrdeQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1103 VTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRE 1182
Cdd:pfam02463  323 KKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1183 SSSIIEAQNTKLNESNVQLEN-------KTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEE 1255
Cdd:pfam02463  403 EEKEAQLLLELARQLEDLLKEekkeeleILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1256 LVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELK-EALCQKENGLKELQGKL 1334
Cdd:pfam02463  483 QEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAiSTAVIVEVSATADEVEE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1335 DESNT-VLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQAneelqKSLQQKQLLLEKGNEFDTQLAEYQKV 1413
Cdd:pfam02463  563 RQKLVrALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKA-----TLEADEDDKRAKVVEGILKDTELTKL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1414 IDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVL--SLKAQMNGASSRSGKG 1491
Cdd:pfam02463  638 KESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLeiKKKEQREKEELKKLKL 717

                          570       580       590
                   ....*....|....*....|....*....|...
gi 442628159  1492 DEVESLDIETSLAKINFLNSIIADMQQKNDALK 1524
Cdd:pfam02463  718 EAEELLADRVQEAQDKINEELKLLKQKIDEEEE 750
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 794-1472 2.37e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.98  E-value: 2.37e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   794 DEISQLKSQAEETQSELKStqsNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLksevgetqaALSSCHTDVESKTKQL 873
Cdd:pfam15921  127 DAMADIRRRESQSQEDLRN---QLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKM---------MLSHEGVLQEIRSILV 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   874 EAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELqaersssSALHTKLSKFSDEIATGHKELTSKADAWSQemlQ 953
Cdd:pfam15921  195 DFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEI-------SYLKGRIFPVEDQLEALKSESQNKIELLLQ---Q 264

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   954 KEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLqeRLEITNAELQHKE 1033
Cdd:pfam15921  265 HQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQL--RSELREAKRMYED 342

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1034 KMASEDAQKIADLKTLVEAiQVANANISATNAELSTVLEVLQAEKSETNHIFELfemEADMNsERLIEKVTGIKEELKET 1113
Cdd:pfam15921  343 KIEELEKQLVLANSELTEA-RTERDQFSQESGNLDDQLQKLLADLHKREKELSL---EKEQN-KRLWDRDTGNSITIDHL 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1114 HLQLDERQKKFEELEEKLKqAQQSEQKLQQESQTSK-EKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNT 1192
Cdd:pfam15921  418 RRELDDRNMEVQRLEALLK-AMKSECQGQMERQMAAiQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSER 496

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1193 KLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGE---LQQVQEANGDIKDSLVKVEELVKVLEEKLQAATs 1269
Cdd:pfam15921  497 TVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEgdhLRNVQTECEALKLQMAEKDKVIEILRQQIENMT- 575

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1270 QLDAQQ---ATNKELQELLVKSQENEGNLQGESLAVTE-----KLQQLEQANGELKEALCQKENG----LKELQGKLDES 1337
Cdd:pfam15921  576 QLVGQHgrtAGAMQVEKAQLEKEINDRRLELQEFKILKdkkdaKIRELEARVSDLELEKVKLVNAgserLRAVKDIKQER 655

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1338 NTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDtqlAEYQKVIDEM 1417
Cdd:pfam15921  656 DQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSD---GHAMKVAMGM 732

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 442628159  1418 DDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSR 1472
Cdd:pfam15921  733 QKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNK 787
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 516-1188 2.37e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 59.21  E-value: 2.37e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   516 AEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQ 595
Cdd:TIGR00618  194 GKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   596 KEGTE--------------EKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLE 661
Cdd:TIGR00618  274 AQEAVleetqerinrarkaAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQ 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   662 KESIEQQLALKQNELEDFQKKQSESE--VHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEK 739
Cdd:TIGR00618  354 EIHIRDAHEVATSIREISCQQHTLTQhiHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQ 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   740 ETIIKEKEQELQ--QLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNL 817
Cdd:TIGR00618  434 ELQQRYAELCAAaiTCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHP 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   818 EAKSKQLeaanGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDL 897
Cdd:TIGR00618  514 NPARQDI----DNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNL 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   898 QDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELT--SKADAWSQEMLQKEKELQELRQQLQDSQDSQTK- 974
Cdd:TIGR00618  590 QNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHlqQCSQELALKLTALHALQLTLTQERVREHALSIRv 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   975 LKAEGERKEKSFEESIKNLQEEVTKAKTE----NLELSTGTQTTIKDLQERLEITNAELQHKEKMASED---AQKIADLK 1047
Cdd:TIGR00618  670 LPKELLASRQLALQKMQSEKEQLTYWKEMlaqcQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREdalNQSLKELM 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1048 TLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEEL 1127
Cdd:TIGR00618  750 HQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQE 829

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 442628159  1128 EEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIE 1188
Cdd:TIGR00618  830 EEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQFDG 890
PTZ00121 PTZ00121
MAEBL; Provisional
 308-907 2.91e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.00  E-value: 2.91e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  308 EKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTE----ELQCSIDEAQFCGDELNA---QS 380
Cdd:PTZ00121 1294 EAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEaakaEAEAAADEAEAAEEKAEAaekKK 1373

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  381 QVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDGALQEEIAKLQEKMTIQQKEV-----------ESRIAEQLE--- 446
Cdd:PTZ00121 1374 EEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKkkadeakkkaeEAKKADEAKkka 1453

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  447 EEQRLRENVKYLNEQIATLQSelvSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLS 526
Cdd:PTZ00121 1454 EEAKKAEEAKKKAEEAKKADE---AKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA 1530

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  527 SE---LQNLKATSDSLESERVNKTDECEILQtEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKS 603
Cdd:PTZ00121 1531 EEakkADEAKKAEEKKKADELKKAEELKKAE-EKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  604 TLLEKTEKELVQSKE--QAAKTLNDKEQLEKQISDLKQLAEQEKlvREMTENAINQIQLEKESIEQQLALKQNELEDFQK 681
Cdd:PTZ00121 1610 EEAKKAEEAKIKAEElkKAEEEKKKVEQLKKKEAEEKKKAEELK--KAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  682 KQSESEVHLQEIKAQNTQ----KDFELVESGESLKKLQQQLEQKTlghEKLQAALEELKKEKETIIKEKEQELQQLQSKS 757
Cdd:PTZ00121 1688 KKAAEALKKEAEEAKKAEelkkKEAEEKKKAEELKKAEEENKIKA---EEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKK 1764

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  758 AESESALKVVQVQLEQLQQQAAASGE----EGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEE 833
Cdd:PTZ00121 1765 EEEKKAEEIRKEKEAVIEEELDEEDEkrrmEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLE 1844

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 442628159  834 EAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANaALEKVNKEYAESRAEASDLQDKVKEITDT 907
Cdd:PTZ00121 1845 EADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEAD-EIEKIDKDDIEREIPNNNMAGKNNDIIDD 1917
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 653-1390 3.51e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 58.49  E-value: 3.51e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   653 NAINQIQLEKESIEQQLALKQNELEDFQKKqsesevhlqeikaqntqkdfelvesgesLKKLQQQLEQKtlgheklqaal 732
Cdd:TIGR04523   26 NIANKQDTEEKQLEKKLKTIKNELKNKEKE----------------------------LKNLDKNLNKD----------- 66

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   733 EELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSktvaKLHDEISQLKSQAEETQSELKS 812
Cdd:TIGR04523   67 EEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKN----KLEVELNKLEKQKKENKKNIDK 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   813 TQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALsschTDVESKTKQLEAANAALEKVNKEYAESRA 892
Cdd:TIGR04523  143 FLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI----DKIKNKLLKLELLLSNLKKKIQKNKSLES 218

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   893 EASDLQDKVKEITDTlhaeLQAERSSSSALHTKLSKFSDEIatghKELTSKADAWSQEMLQKEKELQelrqqlqdsqdsq 972
Cdd:TIGR04523  219 QISELKKQNNQLKDN----IEKKQQEINEKTTEISNTQTQL----NQLKDEQNKIKKQLSEKQKELE------------- 277

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   973 tklkaEGERKEKSFEESIKNLQEEVTKAKTE-NLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVE 1051
Cdd:TIGR04523  278 -----QNNKKIKELEKQLNQLKSEISDLNNQkEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELT 352

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1052 AIQVANANISATNAELSTVLEVLQAEKSETNhifelfemeadmnserliEKVTGIKEELKETHLQLDERQKKFEELEEKL 1131
Cdd:TIGR04523  353 NSESENSEKQRELEEKQNEIEKLKKENQSYK------------------QEIKNLESQINDLESKIQNQEKLNQQKDEQI 414

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1132 KQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEekvressSIIEAQNTKLNESNVQLENKTSCLKET 1211
Cdd:TIGR04523  415 KKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLD-------NTRESLETQLKVLSRSINKIKQNLEQK 487

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1212 QDQLLESQKKEKQLQEEAAKLSgelQQVQEANGDIKDSLVKVEELVKVLEEKlqaatsqldAQQATNKELQELLVKSQEN 1291
Cdd:TIGR04523  488 QKELKSKEKELKKLNEEKKELE---EKVKDLTKKISSLKEKIEKLESEKKEK---------ESKISDLEDELNKDDFELK 555

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1292 EGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSK 1371
Cdd:TIGR04523  556 KENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKN 635

                          730
                   ....*....|....*....
gi 442628159  1372 LAEQLSQLKQANEELQKSL 1390
Cdd:TIGR04523  636 IKSKKNKLKQEVKQIKETI 654
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 614-1412 4.13e-08

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 58.52  E-value: 4.13e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   614 VQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEI 693
Cdd:TIGR00606  185 IKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKI 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   694 -KAQNTQKDFELVEsgESLKKLQQQLEQKTLG-HEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESalKVVQVQL 771
Cdd:TIGR00606  265 mKLDNEIKALKSRK--KQMEKDNSELELKMEKvFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNK--ERRLLNQ 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   772 EQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSK-------QLEAANGSLEEEAKKSGHLLEQ 844
Cdd:TIGR00606  341 EKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQiknfhtlVIERQEDEAKTAAQLCADLQSK 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   845 ITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHT 924
Cdd:TIGR00606  421 ERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLK 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   925 KLSKFsdeIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTEN 1004
Cdd:TIGR00606  501 KEVKS---LQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLED 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1005 LELSTGTQttIKDLQERLEITNAELQHKEKMA----SEDAQKIADLKTLVEAI------QVANANISATNAELSTVLEVL 1074
Cdd:TIGR00606  578 WLHSKSKE--INQTRDRLAKLNKELASLEQNKnhinNELESKEEQLSSYEDKLfdvcgsQDEESDLERLKEEIEKSSKQR 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1075 QAEKSETNHIFELFEMEADMNSE--RLIEKVTGIKEELKETHLQLderQKKFEELEEKLKQAQQSEQKLQQESQTSKEKL 1152
Cdd:TIGR00606  656 AMLAGATAVYSQFITQLTDENQSccPVCQRVFQTEAELQEFISDL---QSKLRLAPDKLKSTESELKKKEKRRDEMLGLA 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1153 TEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKET---QDQLLESQKKEKQLQEEA 1229
Cdd:TIGR00606  733 PGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVtimERFQMELKDVERKIAQQA 812

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1230 AKLSGElqqvqeangDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQL 1309
Cdd:TIGR00606  813 AKLQGS---------DLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRR 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1310 EQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKS 1389
Cdd:TIGR00606  884 QQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENK 963

                          810       820
                   ....*....|....*....|....*...
gi 442628159  1390 LQQ--KQLLLEKGNEFDT---QLAEYQK 1412
Cdd:TIGR00606  964 IQDgkDDYLKQKETELNTvnaQLEECEK 991
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 58-118 4.32e-08

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 58.16  E-value: 4.32e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 442628159   58 IGQRVWLGGTRpGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSR 118
Cdd:COG5244     6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIR 65
PTZ00121 PTZ00121
MAEBL; Provisional
 421-1123 4.44e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.61  E-value: 4.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  421 EEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKfslsecgiENLRRELELLKEEN 500
Cdd:PTZ00121 1293 DEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKA--------EAEAAADEAEAAEE 1364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  501 EKQAQEAQAEFTRKLAE---KSVEVLRLSSELQNlKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQldevttq 577
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADaakKKAEEKKKADEAKK-KAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEA------- 1436

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  578 lnVQKADSSALDDMLRLQKEGTEEKSTLLEKTEkelvqsKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQ 657
Cdd:PTZ00121 1437 --KKKAEEAKKADEAKKKAEEAKKAEEAKKKAE------EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEA 1508

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  658 IQLEKESIEQQLALKQNELEDFQKKQSESEVH-LQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAAlEELK 736
Cdd:PTZ00121 1509 KKKADEAKKAEEAKKADEAKKAEEAKKADEAKkAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKA-EEAK 1587

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  737 KEKETIIKEKEQELQQLQSKSAEsesalKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSN 816
Cdd:PTZ00121 1588 KAEEARIEEVMKLYEEEKKMKAE-----EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK 1662

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  817 LEAKSKQleaangslEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASD 896
Cdd:PTZ00121 1663 AAEEAKK--------AEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEE 1734

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  897 LQDKVKEitDTLHAElqaERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKElqelrqqlqdsqdsqtKLK 976
Cdd:PTZ00121 1735 AKKEAEE--DKKKAE---EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDE----------------KRR 1793

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  977 AEGERKEKSFEESIKNLQEevtKAKTENLELSTGTQTTIKDLQERLEITNAELqhkekmasEDAQKIADLKTLVEAIQVA 1056
Cdd:PTZ00121 1794 MEVDKKIKDIFDNFANIIE---GGKEGNLVINDSKEMEDSAIKEVADSKNMQL--------EEADAFEKHKFNKNNENGE 1862

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 442628159 1057 NANISATNAELSTVLEVLQAEKSETNHIFELfeMEADMNSERLIEKVTGIKEELKETHLQLDERQKK 1123
Cdd:PTZ00121 1863 DGNKEADFNKEKDLKEDDEEEIEEADEIEKI--DKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKR 1927
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1089-1392 5.86e-08

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 57.44  E-value: 5.86e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1089 EMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQ 1168
Cdd:pfam05557   22 ELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQLAD 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1169 KEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKd 1248
Cdd:pfam05557  102 AREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAEAEQRIKELEFEIQ- 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1249 SLVKVEELVKVLEEKLqAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLK 1328
Cdd:pfam05557  181 SQEQDSEIVKNSKSEL-ARIPELEKELERLREHNKHLNENIENKLLLKEEVEDLKRKLEREEKYREEAATLELEKEKLEQ 259

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 442628159  1329 ELQG--KLDESNTVlesQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQ 1392
Cdd:pfam05557  260 ELQSwvKLAQDTGL---NLRSPEDLSRRIEQLQQREIVLKEENSSLTSSARQLEKARRELEQELAQ 322
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 521-1272 6.27e-08

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 57.93  E-value: 6.27e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   521 EVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNvQKADSSALDdmLRLQKEGTE 600
Cdd:pfam12128  242 EFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWK-EKRDELNGE--LSAADAAVA 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   601 EKSTLLEKTEKELVQSKEQAAKTLN-DKEQLEKQISDLKQLAEQEKLVremtENAINQIQLEKESIEQQLALKQN-ELED 678
Cdd:pfam12128  319 KDRSELEALEDQHGAFLDADIETAAaDQEQLPSWQSELENLEERLKAL----TGKHQDVTAKYNRRRSKIKEQNNrDIAG 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   679 FQKKQSesevhlqeikAQNTQKDFELVESGESLKKLQQQLeqktlgHEKLQAALEELKKEKETIIKEKEQELQQLQSKSA 758
Cdd:pfam12128  395 IKDKLA----------KIREARDRQLAVAEDDLQALESEL------REQLEAGKLEFNEEEYRLKSRLGELKLRLNQATA 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   759 ESEsaLKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELK-------STQSNLEAKSKQLEAANGSL 831
Cdd:pfam12128  459 TPE--LLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRqasrrleERQSALDELELQLFPQAGTL 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   832 EEEAKKSGHLLEQ-ITKLKSevgetQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHA 910
Cdd:pfam12128  537 LHFLRKEAPDWEQsIGKVIS-----PELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEE 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   911 ELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQemlqKEKELQELRQQLqdsqdsqtklKAEGERKEKSFEESI 990
Cdd:pfam12128  612 ALQSAREKQAAAEEQLVQANGELEKASREETFARTALKN----ARLDLRRLFDEK----------QSEKDKKNKALAERK 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   991 KNLQEEVTKAKTENLELSTGTQTTIKDLQER-LEITNAELQHKEKMASEDAQKIADLKTLVEAIQV-ANANISATNAELS 1068
Cdd:pfam12128  678 DSANERLNSLEAQLKQLDKKHQAWLEEQKEQkREARTEKQAYWQVVEGALDAQLALLKAAIAARRSgAKAELKALETWYK 757

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1069 TVLEVLQAEKsetnhifelfemeadmnserliEKVTGIKEELKETHLQLdERQKKFEELEEKLKQAQQSeqKLQQESQTS 1148
Cdd:pfam12128  758 RDLASLGVDP----------------------DVIAKLKREIRTLERKI-ERIAVRRQEVLRYFDWYQE--TWLQRRPRL 812

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1149 KEKLTEIQQSLQELQDSVKQKEElvqnleekvresssiieaqNTKLNESNVQLENKTSclKETQDQLLESQKKEKQLQEE 1228
Cdd:pfam12128  813 ATQLSNIERAISELQQQLARLIA-------------------DTKLRRAKLEMERKAS--EKQQVRLSENLRGLRCEMSK 871

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 442628159  1229 AAKLSgELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLD 1272
Cdd:pfam12128  872 LATLK-EDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVE 914
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1262-1491 9.24e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.31  E-value: 9.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1262 EKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVL 1341
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1342 ESQKKSHNEIQDKLEQAQQKERTL----QEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEM 1417
Cdd:COG4942   100 EAQKEELAELLRALYRLGRQPPLAlllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 442628159 1418 DDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKG 1491
Cdd:COG4942   180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKG 253
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1023-1469 1.13e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 56.70  E-value: 1.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1023 EITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANIsatnAELSTVLEVLQAEKSETNHIFELFEMEADMNS-ERLIE 1101
Cdd:COG4717    67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEEL----EELEAELEELREELEKLEKLLQLLPLYQELEAlEAELA 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1102 KVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQS-EQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKV 1180
Cdd:COG4717   143 ELPERLEELEERLEELRELEEELEELEAELAELQEElEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEEL 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1181 RESSSIIEaqntklnesnvQLENKtsclketqdqlLESQKKEKQLQEEAAKLS--GELQQVQEANGDIKDSLVKVEELVK 1258
Cdd:COG4717   223 EELEEELE-----------QLENE-----------LEAAALEERLKEARLLLLiaAALLALLGLGGSLLSLILTIAGVLF 280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1259 VLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1338
Cdd:COG4717   281 LVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELE 360

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1339 TVLEsQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEfDTQLAEYQKVIDEMD 1418
Cdd:COG4717   361 EELQ-LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLE-ALDEEELEEELEELE 438

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 442628159 1419 DAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETK--ELRRQLESLELE 1469
Cdd:COG4717   439 EELEELEEELEELREELAELEAELEQLEEDGELAELLQEleELKAELRELAEE 491
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1213-1484 1.21e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.85  E-value: 1.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1213 DQLLEsqkkEKQLQEEAAKLSGELQQVQEAngdiKDSLVKVEELVKVLE------EKLQAATSQLDAQQATnKELQELLV 1286
Cdd:COG4913   215 EYMLE----EPDTFEAADALVEHFDDLERA----HEALEDAREQIELLEpirelaERYAAARERLAELEYL-RAALRLWF 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1287 KSQENEgnlqgeslAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDEsntvLESQKKSHNeiQDKLEQAQQKERTLQ 1366
Cdd:COG4913   286 AQRRLE--------LLEAELEELRAELARLEAELERLEARLDALREELDE----LEAQIRGNG--GDRLEQLEREIERLE 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1367 EETSKLAEQLSQLKQANEELqkslqqkqlllekGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQAN 1446
Cdd:COG4913   352 RELEERERRRARLEALLAAL-------------GLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLR 418

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 442628159 1447 DaqktaylETKELRRQLESLELEKS---REVLSLKAQMNGA 1484
Cdd:COG4913   419 R-------ELRELEAEIASLERRKSnipARLLALRDALAEA 452
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 562-765 1.24e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.93  E-value: 1.24e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  562 EQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQisdlkqLA 641
Cdd:COG4942    27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE------LE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  642 EQEKLVREMtenaINQIQLEKESIEQQLALKQNELEDFQKKQSesevHLQEIKAQNTQKDFELVESGESLKKLQQQLEQK 721
Cdd:COG4942   101 AQKEELAEL----LRALYRLGRQPPLALLLSPEDFLDAVRRLQ----YLKYLAPARREQAEELRADLAELAALRAELEAE 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 442628159  722 TLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALK 765
Cdd:COG4942   173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELA 216
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1025-1526 1.28e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 56.65  E-value: 1.28e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1025 TNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERlIEKVT 1104
Cdd:pfam05483   97 IEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEK-TKKYE 175

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1105 GIKEELKETHLQLDERQKKFEELEEKLKQaqQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNL-------E 1177
Cdd:pfam05483  176 YEREETRQVYMDLNNNIEKMILAFEELRV--QAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLliqitekE 253

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1178 EKVRESSSIIEAQNTKLNesnvQLENKTsclKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELV 1257
Cdd:pfam05483  254 NKMKDLTFLLEESRDKAN----QLEEKT---KLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTI 326

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1258 KVLEEKLQAATSQLDAQQATNK-----------ELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENG 1326
Cdd:pfam05483  327 CQLTEEKEAQMEELNKAKAAHSfvvtefeattcSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVE 406

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1327 LKELQGKLDESNTVLESQK---KSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEF 1403
Cdd:pfam05483  407 LEELKKILAEDEKLLDEKKqfeKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLK 486

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1404 DTQLA--------EYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAyletKELRRQLESLELEKSREVL 1475
Cdd:pfam05483  487 NIELTahcdklllENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKE----MNLRDELESVREEFIQKGD 562

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 442628159  1476 SLKAQMNgASSRSGKGDEVESLDIETSLA-----------KINFLNSIIADMQQKNDALKAK 1526
Cdd:pfam05483  563 EVKCKLD-KSEENARSIEYEVLKKEKQMKilenkcnnlkkQIENKNKNIEELHQENKALKKK 623
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 931-1532 1.46e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 56.61  E-value: 1.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   931 DEIAtGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEK---------SFEESIKNLQEEVTKAK 1001
Cdd:TIGR02169  160 DEIA-GVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERyqallkekrEYEGYELLKEKEALERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1002 TENLELSTGTQT-TIKDLQERLEITNAELQHKEKMASEDAQKIADL--------KTLVEAIQVANANISATNAELStvLE 1072
Cdd:TIGR02169  239 KEAIERQLASLEeELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeeqlrvKEKIGELEAEIASLERSIAEKE--RE 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1073 VLQAEKSETNHIFELFEMEADM-NSERLIE----KVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQT 1147
Cdd:TIGR02169  317 LEDAEERLAKLEAEIDKLLAEIeELEREIEeerkRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1148 SKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQE 1227
Cdd:TIGR02169  397 LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKE 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1228 EAAKLSGELQQVQE--------------------ANGDIKDSLVK-----VEELVKVLEEKLQAATS------------- 1269
Cdd:TIGR02169  477 EYDRVEKELSKLQRelaeaeaqaraseervrggrAVEEVLKASIQgvhgtVAQLGSVGERYATAIEVaagnrlnnvvved 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1270 QLDAQQATN--KELQ---------------------------------------------------ELLVKSQEN----- 1291
Cdd:TIGR02169  557 DAVAKEAIEllKRRKagratflplnkmrderrdlsilsedgvigfavdlvefdpkyepafkyvfgdTLVVEDIEAarrlm 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1292 --------EGNLQGESLAVT---EKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQ 1360
Cdd:TIGR02169  637 gkyrmvtlEGELFEKSGAMTggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASR 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1361 KERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEkgnEFDTQLAEYQKVIDEMDDAasvksalLEQLQNRVAELET 1440
Cdd:TIGR02169  717 KIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIE---NVKSELKELEARIEELEED-------LHKLEEALNDLEA 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1441 ALRQAndaqktaylETKELRRQLESLELEKSREVLSLkAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKN 1520
Cdd:TIGR02169  787 RLSHS---------RIPEIQAELSKLEEEVSRIEARL-REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEI 856

                          730
                   ....*....|..
gi 442628159  1521 DALKAKVQTLET 1532
Cdd:TIGR02169  857 ENLNGKKEELEE 868
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1094-1387 1.47e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.50  E-value: 1.47e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1094 MNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELV 1173
Cdd:COG3096   340 QTALRQQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAV 419

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1174 QNLE-------------EKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQ------LLES----------QKKEKQ 1224
Cdd:COG3096   420 QALEkaralcglpdltpENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQfekayeLVCKiageversqaWQTARE 499

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1225 LQEEAAK---LSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQEL--LVKSQENEGNLQGES 1299
Cdd:COG3096   500 LLRRYRSqqaLAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELeaQLEELEEQAAEAVEQ 579

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1300 LAVTEklQQLEQANGELKEaLCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQL 1379
Cdd:COG3096   580 RSELR--QQLEQLRARIKE-LAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQLLEREREATVERDELAARKQAL 656


                  ....*...
gi 442628159 1380 KQANEELQ 1387
Cdd:COG3096   657 ESQIERLS 664
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1109-1319 1.75e-07

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 55.22  E-value: 1.75e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1109 ELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIE 1188
Cdd:COG3883    17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1189 AQNTKLNESNVQLENKT-----------SCLKETQDQLLESQKKEK-QLQEEAAKLSGELQQVQEANGDIKDSLVKVEEL 1256
Cdd:COG3883    97 RSGGSVSYLDVLLGSESfsdfldrlsalSKIADADADLLEELKADKaELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442628159 1257 VKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEA 1319
Cdd:COG3883   177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 239
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 807-1493 1.83e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.50  E-value: 1.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  807 QSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTdvesKTKQLEAANAALEKvnke 886
Cdd:COG3096   353 QEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQT----RAIQYQQAVQALEK---- 424

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  887 yAESRAEASDL-QDKVKEITDTLHAELQAERSSSSALHTKLSkFSDEIATGHKEL----------TSKADAWS--QEMLq 953
Cdd:COG3096   425 -ARALCGLPDLtPENAEDYLAAFRAKEQQATEEVLELEQKLS-VADAARRQFEKAyelvckiageVERSQAWQtaRELL- 501

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  954 keKELQELRQQLQDSQDSQTKLkAEGERKEKSfEESIKNLQEEVTKAKTENLElstgTQTTIKDLQERLEITNAELqhkE 1033
Cdd:COG3096   502 --RRYRSQQALAQRLQQLRAQL-AELEQRLRQ-QQNAERLLEEFCQRIGQQLD----AAEELEELLAELEAQLEEL---E 570

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1034 KMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFElfemeadmNSERLIEKVTGIKEELKET 1113
Cdd:COG3096   571 EQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEALA--------DSQEVTAAMQQLLEREREA 642

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1114 HLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQqsLQELQDSVKQKE----------------------- 1170
Cdd:COG3096   643 TVERDELAARKQALESQIERLSQPGGAEDPRLLALAERLGGVL--LSEIYDDVTLEDapyfsalygparhaivvpdlsav 720

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1171 -ELVQNLEEkVRESSSIIEAQNTKLNES--NVQLENKTSCLKETQDQLLESQ----------KKEKQLQ----------E 1227
Cdd:COG3096   721 kEQLAGLED-CPEDLYLIEGDPDSFDDSvfDAEELEDAVVVKLSDRQWRYSRfpevplfgraAREKRLEelraerdelaE 799

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1228 EAAKLSGELQQVQEANGDIKDSLVK---------VEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQG- 1297
Cdd:COG3096   800 QYAKASFDVQKLQRLHQAFSQFVGGhlavafapdPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKl 879

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1298 ---------ESLAvtEKLQQLEQANGELKEA---LCQKENGLKELQGKLDesntVLESQKKSHNEIQDKLEQAQQKERTL 1365
Cdd:COG3096   880 lpqanlladETLA--DRLEELREELDAAQEAqafIQQHGKALAQLEPLVA----VLQSDPEQFEQLQADYLQAKEQQRRL 953

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1366 QEETSKLAE---------------QLSQLKQANEELQKSLQQKQLLLEKGNE----FDTQLAEYQKVIDEMDDAASVKSA 1426
Cdd:COG3096   954 KQQIFALSEvvqrrphfsyedavgLLGENSDLNEKLRARLEQAEEARREAREqlrqAQAQYSQYNQVLASLKSSRDAKQQ 1033

                         730       740       750       760       770       780       790
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 442628159 1427 LLEQLQNRVAELEtaLRQANDAQKTAYLETKELRRQLESL-----ELEKSREVlsLKAQMNGASSRSGKGDE 1493
Cdd:COG3096  1034 TLQELEQELEELG--VQADAEAEERARIRRDELHEELSQNrsrrsQLEKQLTR--CEAEMDSLQKRLRKAER 1101
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1100-1481 2.02e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.93  E-value: 2.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1100 IEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQtSKEKLTEIQQSLQELQDSVKQKEELVQNLEEK 1179
Cdd:COG4717    73 LKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE-KLEKLLQLLPLYQELEALEAELAELPERLEEL 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1180 VRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKV 1259
Cdd:COG4717   152 EERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQ 231

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1260 LEEKL--QAATSQLDAQQATNKELQELLVKSQENE-----------------GNLQGESLAVTEKLQQLEQANGELKEAL 1320
Cdd:COG4717   232 LENELeaAALEERLKEARLLLLIAAALLALLGLGGsllsliltiagvlflvlGLLALLFLLLAREKASLGKEAEELQALP 311

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1321 CQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQAN-------------EELQ 1387
Cdd:COG4717   312 ALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAAllaeagvedeeelRAAL 391

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1388 KSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASvksalLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLE 1467
Cdd:COG4717   392 EQAEEYQELKEELEELEEQLEELLGELEELLEALD-----EEELEEELEELEEELEELEEELEELREELAELEAELEQLE 466

                         410
                  ....*....|....
gi 442628159 1468 LEKSREVLSLKAQM 1481
Cdd:COG4717   467 EDGELAELLQELEE 480
COG5022 COG5022
Myosin heavy chain [General function prediction only];
979-1438 2.12e-07

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 56.24  E-value: 2.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  979 GERKE-KSFEESIKNLQEEVTKAKT-----------ENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQK-IAD 1045
Cdd:COG5022   807 GSRKEyRSYLACIIKLQKTIKREKKlreteevefslKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVELAERqLQE 886

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1046 LKTLVEAIQvanaNISATNAEL-STVLEVLQAEKS----ETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDER 1120
Cdd:COG5022   887 LKIDVKSIS----SLKLVNLELeSEIIELKKSLSSdlieNLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPELNKLHEV 962

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1121 QKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESnvq 1200
Cdd:COG5022   963 ESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSES--- 1039

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1201 leNKTSCLKETQDQLLESQKKEKQLQEEAAKLsgelqQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKE 1280
Cdd:COG5022  1040 --TELSILKPLQKLKGLLLLENNQLQARYKAL-----KLRRENSLLDDKQLYQLESTENLLKTINVKDLEVTNRNLVKPA 1112

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1281 -LQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEAlcqkengLKELQGKLDESNTVLESQKKSHNEIQDKLEQA- 1358
Cdd:COG5022  1113 nVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVL-------QLELDGLFWEANLEALPSPPPFAALSEKRLYQs 1185

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1359 ---QQKERTLQEETSKLAEQLSQL-KQANEELQKSLQQKQLLLEK--GNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQ 1432
Cdd:COG5022  1186 alyDEKSKLSSSEVNDLKNELIALfSKIFSGWPRGDKLKKLISEGwvPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSLL 1265


                  ....*.
gi 442628159 1433 NRVAEL 1438
Cdd:COG5022  1266 NSIDNL 1271
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1097-1475 2.20e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.54  E-value: 2.20e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1097 ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSK--EKLTEIQQSLQELQ---DSVKQKEE 1171
Cdd:COG4717    77 EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPerlEELEERLE 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1172 LVQNLEEKVRESSSIIEAQNTKLNESNVQLENKT-SCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSL 1250
Cdd:COG4717   157 ELRELEEELEELEAELAELQEELEELLEQLSLATeEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENEL 236

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1251 VKVEELVKVLEEK-LQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALcQKENGLKE 1329
Cdd:COG4717   237 EAAALEERLKEARlLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEEL-QALPALEE 315

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1330 LQGKldESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQkslqQKQLLLEKGNEFDTQLAE 1409
Cdd:COG4717   316 LEEE--ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQE----IAALLAEAGVEDEEELRA 389

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 442628159 1410 YQKVIDEMDDAAsvksALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVL 1475
Cdd:COG4717   390 ALEQAEEYQELK----EELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEEL 451
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
606-1342 2.24e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.08  E-value: 2.24e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  606 LEKTEKELVQSKEQAaKTLND-KEQLEKQISDLKQLAEQEKLVREMT----ENAINQIQLEKESIEQQLALKQNELEDFQ 680
Cdd:COG4913   237 LERAHEALEDAREQI-ELLEPiRELAERYAAARERLAELEYLRAALRlwfaQRRLELLEAELEELRAELARLEAELERLE 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  681 KKQSESEVHLQEIKAQNTQKDfelvesGESLKKLQQQLEQKTLGHEKLQAALEELkkeketiikekEQELQQLQSKSAES 760
Cdd:COG4913   316 ARLDALREELDELEAQIRGNG------GDRLEQLEREIERLERELEERERRRARL-----------EALLAALGLPLPAS 378

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  761 ESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSE---LKSTQSNLEAKS----KQLEAANGSLEE 833
Cdd:COG4913   379 AEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEiasLERRKSNIPARLlalrDALAEALGLDEA 458

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  834 EAKKSGHLLEqitkLKSEVGETQAA----LSSCHTD--VESktkqlEAANAALEKVNKEYAESRaeasdLQ-DKVKEITD 906
Cdd:COG4913   459 ELPFVGELIE----VRPEEERWRGAiervLGGFALTllVPP-----EHYAAALRWVNRLHLRGR-----LVyERVRTGLP 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  907 TLHAELQAERSSSSALHTKLSKFSDEIatgHKELTSKADAWSQEmlqkekELQELRQqlqdsqdsqtklkaegerkeksf 986
Cdd:COG4913   525 DPERPRLDPDSLAGKLDFKPHPFRAWL---EAELGRRFDYVCVD------SPEELRR----------------------- 572

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  987 eesiknlqeeVTKAKTENLELSTGTQTTIKDLQERLEitnAELQhkekMASEDAQKIADLKTLVEAIQVANANISATNAE 1066
Cdd:COG4913   573 ----------HPRAITRAGQVKGNGTRHEKDDRRRIR---SRYV----LGFDNRAKLAALEAELAELEEELAEAEERLEA 635

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1067 LSTVLEVLQAEKSETNHIFELFEMEADMNSerLIEKVTGIKEELKethlQLDERQKKFEELEEKLKQAQQSEQKLQQESQ 1146
Cdd:COG4913   636 LEAELDALQERREALQRLAEYSWDEIDVAS--AEREIAELEAELE----RLDASSDDLAALEEQLEELEAELEELEEELD 709

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1147 TSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVResssiiEAQNTKLnesnvqlenktsclketqDQLLESQKKEKQLQ 1226
Cdd:COG4913   710 ELKGEIGRLEKELEQAEEELDELQDRLEAAEDLAR------LELRALL------------------EERFAAALGDAVER 765

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1227 EEAAKLSGELQQVQEANGDikdslvKVEELVKVLEEKLQ---AATSQLDAQQATNKELQELLVKsqenegnLQGESLAVT 1303
Cdd:COG4913   766 ELRENLEERIDALRARLNR------AEEELERAMRAFNRewpAETADLDADLESLPEYLALLDR-------LEEDGLPEY 832

                         730       740       750       760
                  ....*....|....*....|....*....|....*....|..
gi 442628159 1304 EK--LQQLEQANGELKEALCQK-ENGLKELQGKLDESNTVLE 1342
Cdd:COG4913   833 EErfKELLNENSIEFVADLLSKlRRAIREIKERIDPLNDSLK 874
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 600-1470 2.37e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.11  E-value: 2.37e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  600 EEKSTLLEKT---EKELVQSKEQAAktlNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQ--LALKQN 674
Cdd:COG3096   278 NERRELSERAlelRRELFGARRQLA---EEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQekIERYQE 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  675 ELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQL--------EQKTLGHEKLQA--ALEELK-------- 736
Cdd:COG3096   355 DLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLadyqqaldVQQTRAIQYQQAvqALEKARalcglpdl 434

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  737 -----KEKETIIKEKEQELQQ----LQSKSAESESALKVVqvqleqlqqqaaasgEEGSKTVAKLHDEISqlKSQAEETQ 807
Cdd:COG3096   435 tpenaEDYLAAFRAKEQQATEevleLEQKLSVADAARRQF---------------EKAYELVCKIAGEVE--RSQAWQTA 497

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  808 SELKSTQSNLEAKSKQLEAANGSLEEEAKksghLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEY 887
Cdd:COG3096   498 RELLRRYRSQQALAQRLQQLRAQLAELEQ----RLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQA 573

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  888 AESRAEASDLQDKVKEITdTLHAELQAERSSSSALHTKLSKFSDEIatgHKELTSKAD--AWSQEMLQKEKELQELRQQL 965
Cdd:COG3096   574 AEAVEQRSELRQQLEQLR-ARIKELAARAPAWLAAQDALERLREQS---GEALADSQEvtAAMQQLLEREREATVERDEL 649

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  966 QdsqdsqtklkaegERKEkSFEESIKNLQEevtKAKTENLELSTgtqttikdLQERLeitNAELQHK--EKMASEDAQKI 1043
Cdd:COG3096   650 A-------------ARKQ-ALESQIERLSQ---PGGAEDPRLLA--------LAERL---GGVLLSEiyDDVTLEDAPYF 701

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1044 -ADLKTLVEAIQVAnanisatnaELSTVLEVLQAEKSETNHIFeLFEMEADMNSERLIEKvtgikEELKETHL-QLDERQ 1121
Cdd:COG3096   702 sALYGPARHAIVVP---------DLSAVKEQLAGLEDCPEDLY-LIEGDPDSFDDSVFDA-----EELEDAVVvKLSDRQ 766

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1122 ---KKFEEL--------EEKLKqaqqseqKLQQESQTSKEKLTEIQQSLQELQdsvkqkeELVQNLEEKVRESSSII--- 1187
Cdd:COG3096   767 wrySRFPEVplfgraarEKRLE-------ELRAERDELAEQYAKASFDVQKLQ-------RLHQAFSQFVGGHLAVAfap 832

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1188 --EAQNTKLNESNVQLEnktsclketqDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIkdSLVK---VEELVKVLEE 1262
Cdd:COG3096   833 dpEAELAALRQRRSELE----------RELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQA--NLLAdetLADRLEELRE 900

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1263 KLQAATSQ---LDAQQATNKELQELLVKSQ---ENEGNLQGESLAVTEKLQQLEQANGELKEALCQKEN-GLKELQGKLD 1335
Cdd:COG3096   901 ELDAAQEAqafIQQHGKALAQLEPLVAVLQsdpEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHfSYEDAVGLLG 980

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1336 ESNTVLESqkkshneIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLekgNEFDTQLAEYQKVID 1415
Cdd:COG3096   981 ENSDLNEK-------LRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTL---QELEQELEELGVQAD 1050

                         890       900       910       920       930
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 442628159 1416 emDDAAsvksallEQLQNRVAELETALRQaNDAQKTaYLETKELRRQLESLELEK 1470
Cdd:COG3096  1051 --AEAE-------ERARIRRDELHEELSQ-NRSRRS-QLEKQLTRCEAEMDSLQK 1094
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
983-1487 4.05e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.92  E-value: 4.05e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  983 EKSFEESIKNLQEEVtkaktENLElstGTQTTIKDLQERLEITNAELQHKEKMAsEDAQKIADLKTLVEAIQVANANISA 1062
Cdd:COG4913   220 EPDTFEAADALVEHF-----DDLE---RAHEALEDAREQIELLEPIRELAERYA-AARERLAELEYLRAALRLWFAQRRL 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1063 tnAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIE-----------KVTGIKEELKETHLQLDERQKKFEELEEKL 1131
Cdd:COG4913   291 --ELLEAELEELRAELARLEAELERLEARLDALREELDEleaqirgnggdRLEQLEREIERLERELEERERRRARLEALL 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1132 KQAQQSE-------QKLQQESQTSKEKLTEIQQSLQELQDSVKQKEelvQNLEEKVRESSSIIEAqntklnesnvqLENK 1204
Cdd:COG4913   369 AALGLPLpasaeefAALRAEAAALLEALEEELEALEEALAEAEAAL---RDLRRELRELEAEIAS-----------LERR 434

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1205 TSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKV----------------------------EEL 1256
Cdd:COG4913   435 KSNIPARLLALRDALAEALGLDEAELPFVGELIEVRPEEERWRGAIERVlggfaltllvppehyaaalrwvnrlhlrGRL 514

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1257 V--KVLEEKLQAATSQLDAQQATNK----------ELQELLVKSQ-----ENEGNLQGESLAVTEKLQ------------ 1307
Cdd:COG4913   515 VyeRVRTGLPDPERPRLDPDSLAGKldfkphpfraWLEAELGRRFdyvcvDSPEELRRHPRAITRAGQvkgngtrhekdd 594

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1308 --------QLEQANGELKEALcQKEngLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKE---------RTLQEETS 1370
Cdd:COG4913   595 rrrirsryVLGFDNRAKLAAL-EAE--LAELEEELAEAEERLEALEAELDALQERREALQRLAeyswdeidvASAEREIA 671

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1371 KLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQK 1450
Cdd:COG4913   672 ELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL 751

                         570       580       590
                  ....*....|....*....|....*....|....*..
gi 442628159 1451 TAYLETKELRRQLESLELEKSREVLSLKAQMNGASSR 1487
Cdd:COG4913   752 EERFAAALGDAVERELRENLEERIDALRARLNRAEEE 788
PRK11281 PRK11281
mechanosensitive channel MscK;
1209-1452 4.22e-07

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 54.92  E-value: 4.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1209 KETQDQLlESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLE---EKLQAATSQLDAQQATNKElqell 1285
Cdd:PRK11281   39 ADVQAQL-DALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQQLAqapAKLRQAQAELEALKDDNDE----- 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1286 VKSQENEgnlqgeslavTEKLQQLEQangelkeALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKertL 1365
Cdd:PRK11281  113 ETRETLS----------TLSLRQLES-------RLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQR---L 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1366 QEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAE--------YQKVIDEMddaaSVKSALLEQ----LQN 1433
Cdd:PRK11281  173 QQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQRKSLEgntqlqdlLQKQRDYL----TARIQRLEHqlqlLQE 248

                         250       260
                  ....*....|....*....|....
gi 442628159 1434 -----RVAELETALRQANDAQKTA 1452
Cdd:PRK11281  249 ainskRLTLSEKTVQEAQSQDEAA 272
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 338-1456 4.23e-07

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 55.44  E-value: 4.23e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   338 INELKARIVELESALDNERKKTEELQCS----IDE--AQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILppd 411
Cdd:TIGR01612 1113 INKIKDDIKNLDQKIDHHIKALEEIKKKsenyIDEikAQINDLEDVADKAISNDDPEEIEKKIENIVTKIDKKKNIY--- 1189

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   412 lpSDDGALQEEIAKLQEKMTIQQ----------KEVESRIAEQLEEEQRLRENVkylneqIATLQSELVSKDEALEKFSL 481
Cdd:TIGR01612 1190 --DEIKKLLNEIAEIEKDKTSLEevkginlsygKNLGKLFLEKIDEEKKKSEHM------IKAMEAYIEDLDEIKEKSPE 1261

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   482 SECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSelqnLKATSDSLESERVNktDECEILQTEVRMRD 561
Cdd:TIGR01612 1262 IENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISDIREKS----LKIIEDFSEESDIN--DIKKELQKNLLDAQ 1335

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   562 EQIRELNQQLDEVTTQLNVQKadssalddmlrlqkegteekstlLEKTEKELVQSKEQAaktlNDKEQLEKQISDlkQLA 641
Cdd:TIGR01612 1336 KHNSDINLYLNEIANIYNILK-----------------------LNKIKKIIDEVKEYT----KEIEENNKNIKD--ELD 1386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   642 EQEKLVREMTENainqIQLEKESIEQQLALKQNELEDFQKKQSESEVHlqeIKAQNTQKDFELVESGESLKKLQQQLEQK 721
Cdd:TIGR01612 1387 KSEKLIKKIKDD----INLEECKSKIESTLDDKDIDECIKKIKELKNH---ILSEESNIDTYFKNADENNENVLLLFKNI 1459

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   722 TLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSaeseSALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLks 801
Cdd:TIGR01612 1460 EMADNKSQHILKIKKDNATNDHDFNINELKEHIDKS----KGCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSAL-- 1533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   802 qaeETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALE 881
Cdd:TIGR01612 1534 ---AIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFL 1610

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   882 KVnkeyaesraeaSDLQDKVKE-ITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAwSQEMLQKEKELQE 960
Cdd:TIGR01612 1611 KI-----------SDIKKKINDcLKETESIEKKISSFSIDSQDTELKENGDNLNSLQEFLESLKDQ-KKNIEDKKKELDE 1678

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   961 LRQQLQdsqdsqtKLKAEGERKEKSFEESIKNLQEEVTKAKTENLE-LSTGTQTTIKDLQERLEITNAE-LQHKEKMASE 1038
Cdd:TIGR01612 1679 LDSEIE-------KIEIDVDQHKKNYEIGIIEKIKEIAIANKEEIEsIKELIEPTIENLISSFNTNDLEgIDPNEKLEEY 1751

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1039 DAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLD 1118
Cdd:TIGR01612 1752 NTEIGDIYEEFIELYNIIAGCLETVSKEPITYDEIKNTRINAQNEFLKIIEIEKKSKSYLDDIEAKEFDRIINHFKKKLD 1831

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1119 ERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKlteiqqslQELQDSVKQKEELVQNLEEKV-----RESSSIIEAQNTK 1193
Cdd:TIGR01612 1832 HVNDKFTKEYSKINEGFDDISKSIENVKNSTDE--------NLLFDILNKTKDAYAGIIGKKyysykDEAEKIFINISKL 1903

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1194 LNESNVQLENKT--SCLKETQDQLLESQKKEKqlqEEAAKLSGELQQVQEANGDIKDSLVKVEELVKvleeklqaatsql 1271
Cdd:TIGR01612 1904 ANSINIQIQNNSgiDLFDNINIAILSSLDSEK---EDTLKFIPSPEKEPEIYTKIRDSYDTLLDIFK------------- 1967

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1272 dAQQATNKELQELLvksqenegNLQGESLAVTEKLQQLEQANGELKEALCQKE---NGLKELQGKLDESN---------- 1338
Cdd:TIGR01612 1968 -KSQDLHKKEQDTL--------NIIFENQQLYEKIQASNELKDTLSDLKYKKEkilNDVKLLLHKFDELNklscdsqnyd 2038

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1339 TVLESQKksHNEIQDKLEQAQQKERTL--QEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE 1416
Cdd:TIGR01612 2039 TILELSK--QDKIKEKIDNYEKEKEKFgiDFDVKAMEEKFDNDIKDIEKFENNYKHSEKDNHDFSEEKDNIIQSKKKLKE 2116

                         1130      1140      1150      1160
                   ....*....|....*....|....*....|....*....|
gi 442628159  1417 MDDAASVKsalLEQLQNRVAELETALRQANDAQKTAYLET 1456
Cdd:TIGR01612 2117 LTEAFNTE---IKIIEDKIIEKNDLIDKLIEMRKECLLFS 2153
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 950-1462 4.99e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 54.73  E-value: 4.99e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   950 EMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKaktenlelSTGTQTTIKDLQERLEITNAEL 1029
Cdd:pfam05483  100 ELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKE--------NNATRHLCNLLKETCARSAEKT 171

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1030 QHKEKMASEDAQKIADLKTLVEAIQVA--NANISATNAELSTVLEvLQAEKSETNHIFELFEMEADMNSER---LIEKVT 1104
Cdd:pfam05483  172 KKYEYEREETRQVYMDLNNNIEKMILAfeELRVQAENARLEMHFK-LKEDHEKIQHLEEEYKKEINDKEKQvslLLIQIT 250

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1105 GIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESS 1184
Cdd:pfam05483  251 EKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLT 330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1185 SIIEAQNTKLNESN-------VQLENKTSCLKE---TQDQLLEsqKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVE 1254
Cdd:pfam05483  331 EEKEAQMEELNKAKaahsfvvTEFEATTCSLEEllrTEQQRLE--KNEDQLKIITMELQKKSSELEEMTKFKNNKEVELE 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1255 ELVKVLEEKlqaaTSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGK- 1333
Cdd:pfam05483  409 ELKKILAED----EKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEk 484

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1334 ------LDESNTVLESQKKSHNEIQD---KLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQ-KQLLLEKGNEF 1403
Cdd:pfam05483  485 lknielTAHCDKLLLENKELTQEASDmtlELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESvREEFIQKGDEV 564

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 442628159  1404 DTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQ 1462
Cdd:pfam05483  565 KCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKK 623
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 734-1398 6.00e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 54.67  E-value: 6.00e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   734 ELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGS-------KTVAKLHDEISQL------- 799
Cdd:TIGR00606  109 EFKTLEGVITRYKHGEKVSLSSKCAEIDREMISHLGVSKAVLNNVIFCHQEDSnwplsegKALKQKFDEIFSAtryikal 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   800 ----------KSQAEETQSELKSTQSNLEAKSK---QLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHtDV 866
Cdd:TIGR00606  189 etlrqvrqtqGQKVQEHQMELKYLKQYKEKACEirdQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIM-KL 267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   867 ESKTKQLEAANAALEKVNKEYAESRAEA-SDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKAD 945
Cdd:TIGR00606  268 DNEIKALKSRKKQMEKDNSELELKMEKVfQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLV 347

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   946 AWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTEnlELSTGTQTTikdlqerleit 1025
Cdd:TIGR00606  348 EQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQED--EAKTAAQLC----------- 414

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1026 nAELQHKEKMASEDAQKIADLKT-LVEAIQVANANISATNAELSTVLEVLQaeksetnhifelfemEADMNSERLIEKvt 1104
Cdd:TIGR00606  415 -ADLQSKERLKQEQADEIRDEKKgLGRTIELKKEILEKKQEELKFVIKELQ---------------QLEGSSDRILEL-- 476

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1105 giKEELKETHLQLDERQKKfeELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESS 1184
Cdd:TIGR00606  477 --DQELRKAERELSKAEKN--SLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIR 552

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1185 SIIEAQNTKLNESNVQLENKtsclKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKL 1264
Cdd:TIGR00606  553 KIKSRHSDELTSLLGYFPNK----KQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKL 628

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1265 QAATSQlDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLE--------------QANGELKEALCQKENGLKEL 1330
Cdd:TIGR00606  629 FDVCGS-QDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTdenqsccpvcqrvfQTEAELQEFISDLQSKLRLA 707

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442628159  1331 QGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLE 1398
Cdd:TIGR00606  708 PDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLG 775
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 993-1483 6.29e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 54.46  E-value: 6.29e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   993 LQEEVTKAKTENLELST------GTQTTIKDLQERLEITNAELqhKEKMASEDAQkiadlktlveaiqvANANISATNAE 1066
Cdd:pfam12128  246 LQQEFNTLESAELRLSHlhfgykSDETLIASRQEERQETSAEL--NQLLRTLDDQ--------------WKEKRDELNGE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1067 LSTVLEVLQAEKSEtnhiFELFEMEADMNSERLIEKVTGIKEelkethlQLDERQKKFEELEEKLKQAQQSEQKLQQESQ 1146
Cdd:pfam12128  310 LSAADAAVAKDRSE----LEALEDQHGAFLDADIETAAADQE-------QLPSWQSELENLEERLKALTGKHQDVTAKYN 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1147 TSKEKLteiqqSLQELQDSVKQKEELVQNLEEKVR---ESSSIIEAQNTKLNEsnvqlenktsclkETQDQLLESQKKEK 1223
Cdd:pfam12128  379 RRRSKI-----KEQNNRDIAGIKDKLAKIREARDRqlaVAEDDLQALESELRE-------------QLEAGKLEFNEEEY 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1224 QLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQqatnKELQELLVKSQENEGNLQGESLAVT 1303
Cdd:pfam12128  441 RLKSRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAANAEVERLQ----SELRQARKRRDQASEALRQASRRLE 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1304 EKLQQLEQAN-------GELKEALCQKENGLKELQGKL---------------------DESN---TVLESQKKSHNEIQ 1352
Cdd:pfam12128  517 ERQSALDELElqlfpqaGTLLHFLRKEAPDWEQSIGKVispellhrtdldpevwdgsvgGELNlygVKLDLKRIDVPEWA 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1353 DKLEQAQQK----ERTLQEETSKLAEQLSQLKQANEELQKS---------------LQQKQLLLEKGNEFDT---QLAEY 1410
Cdd:pfam12128  597 ASEEELRERldkaEEALQSAREKQAAAEEQLVQANGELEKAsreetfartalknarLDLRRLFDEKQSEKDKknkALAER 676

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442628159  1411 QK-VIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRR-QLESLELEKSREVLSLKAQMNG 1483
Cdd:pfam12128  677 KDsANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDaQLALLKAAIAARRSGAKAELKA 751
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 786-1010 8.83e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 8.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  786 SKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTD 865
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  866 VESKTKQLEAANAALEKVNKEY-------AESRAEASDLQDKVKEITDTLHA---ELQAERSSSSALHTKLSKFSDEIAT 935
Cdd:COG4942    99 LEAQKEELAELLRALYRLGRQPplalllsPEDFLDAVRRLQYLKYLAPARREqaeELRADLAELAALRAELEAERAELEA 178

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442628159  936 GHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTG 1010
Cdd:COG4942   179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKG 253
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 420-703 1.07e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 53.59  E-value: 1.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   420 QEEIAKLQEKMTIQQKevesRIAEQLEEEQRLRENVKYLNEQIATLqselVSKDEALEKFSLSECGIENLRRELELLKEE 499
Cdd:pfam17380  332 QAAIYAEQERMAMERE----RELERIRQEERKRELERIRQEEIAME----ISRMRELERLQMERQQKNERVRQELEAARK 403

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   500 NEKQAQEAQaeftRKLAEKSVEVLRLSSELQNLKATS-DSLESERVNktdECEILQTEVRMRDEQIRELNQQLDEvttql 578
Cdd:pfam17380  404 VKILEEERQ----RKIQQQKVEMEQIRAEQEEARQREvRRLEEERAR---EMERVRLEEQERQQQVERLRQQEEE----- 471

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   579 nvQKADSSALDDMLRLQKEGTEEKSTLLEKtekELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQI 658
Cdd:pfam17380  472 --RKRKKLELEKEKRDRKRAEEQRRKILEK---ELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQ 546

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 442628159   659 QL-EKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFE 703
Cdd:pfam17380  547 EMeERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYE 592
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 940-1198 1.10e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.84  E-value: 1.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  940 LTSKADAWSQEMLQKEKELQELRQQLQDSQdsqtKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELstgtQTTIKDLQ 1019
Cdd:COG4942    11 LALAAAAQADAAAEAEAELEQLQQEIAELE----KELAALKKEEKALLKQLAALERRIAALARRIRAL----EQELAALE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1020 ERLEITNAELQHKEKmaSEDAQKiADLKTLVEAIQvananisaTNAELSTVLEVLQAEKSetNHIFELFEMEADMNSERl 1099
Cdd:COG4942    83 AELAELEKEIAELRA--ELEAQK-EELAELLRALY--------RLGRQPPLALLLSPEDF--LDAVRRLQYLKYLAPAR- 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1100 IEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEK 1179
Cdd:COG4942   149 REQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228

                         250
                  ....*....|....*....
gi 442628159 1180 VRESSSIIEAQNTKLNESN 1198
Cdd:COG4942   229 IARLEAEAAAAAERTPAAG 247
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
833-1455 1.18e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.77  E-value: 1.18e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  833 EEAKKSGHLLEQITKLKSEVGETQAALSSCHT-----DVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDT 907
Cdd:COG4913   245 EDAREQIELLEPIRELAERYAAARERLAELEYlraalRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREE 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  908 LhAELQAERSSSsalhtklskfsdeiatGHKELtskaDAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFE 987
Cdd:COG4913   325 L-DELEAQIRGN----------------GGDRL----EQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFA 383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  988 ESIKNLQEEVTKAKTE---NLELSTGTQTTIKDLQERLEITNAELQH---------------KEKMASEDAQKIADLKTL 1049
Cdd:COG4913   384 ALRAEAAALLEALEEEleaLEEALAEAEAALRDLRRELRELEAEIASlerrksniparllalRDALAEALGLDEAELPFV 463

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1050 VEAIQVANANISATNA-E----------------LSTVLEVLQAEKSETNHIFELFE--------MEADMNSerLIEKVT 1104
Cdd:COG4913   464 GELIEVRPEEERWRGAiErvlggfaltllvppehYAAALRWVNRLHLRGRLVYERVRtglpdperPRLDPDS--LAGKLD 541

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1105 gIK------------------------EELKE---------------THLQLDERQKKFEEL------EEKLKQAQQSEQ 1139
Cdd:COG4913   542 -FKphpfrawleaelgrrfdyvcvdspEELRRhpraitragqvkgngTRHEKDDRRRIRSRYvlgfdnRAKLAALEAELA 620

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1140 KLQQESQTSKEKLTEIQQSLQELQdsvkQKEELVQNLEEKVRESSSIIEAQnTKLNESNVQLENktscLKETQDQLLESQ 1219
Cdd:COG4913   621 ELEEELAEAEERLEALEAELDALQ----ERREALQRLAEYSWDEIDVASAE-REIAELEAELER----LDASSDDLAALE 691

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1220 KKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATN--KELQELLVKSQENE--GNL 1295
Cdd:COG4913   692 EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALleERFAAALGDAVERElrENL 771

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1296 QGESLAVTEKLQQLEQANGELKEALCQK-ENGLKELQGKLDEsntvLESQKKSHNEIQ-DKLEQAQQKERTLQEETS--K 1371
Cdd:COG4913   772 EERIDALRARLNRAEEELERAMRAFNREwPAETADLDADLES----LPEYLALLDRLEeDGLPEYEERFKELLNENSieF 847

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1372 LAEQLSQLKQANEE-------LQKSLQQKQ------LLLEKGNEFDTQLAEYQKVIDEMDDAASVKSA-LLEQLQNRVAE 1437
Cdd:COG4913   848 VADLLSKLRRAIREikeridpLNDSLKRIPfgpgryLRLEARPRPDPEVREFRQELRAVTSGASLFDEeLSEARFAALKR 927

                         730
                  ....*....|....*...
gi 442628159 1438 LETALRQANDAQKTAYLE 1455
Cdd:COG4913   928 LIERLRSEEEESDRRWRA 945
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1601-1617 1.25e-06

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 45.92  E-value: 1.25e-06
                           10
                   ....*....|....*..
gi 442628159  1601 RKYCDSCEVFGHDTSEC 1617
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
PRK12704 PRK12704
phosphodiesterase; Provisional
 627-759 1.37e-06

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 52.86  E-value: 1.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  627 KEQLEKQISDLKQLAEQeklVREMTENAINQIQLEKESIEQQLALKQNEleDFQKKQSESEVHLQEIKAQNTQKDFELVE 706
Cdd:PRK12704   26 KKIAEAKIKEAEEEAKR---ILEEAKKEAEAIKKEALLEAKEEIHKLRN--EFEKELRERRNELQKLEKRLLQKEENLDR 100

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 442628159  707 SGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAE 759
Cdd:PRK12704  101 KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAE 153
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1116-1438 1.43e-06

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 53.13  E-value: 1.43e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1116 QLDERQkkfeeLEEKLKQAQQSEQKLQQES----QTSKEKLTEIQQSL---QELQDSVKQKEELVQNLEEKVRESSSiiE 1188
Cdd:PRK10929   22 APDEKQ-----ITQELEQAKAAKTPAQAEIvealQSALNWLEERKGSLeraKQYQQVIDNFPKLSAELRQQLNNERD--E 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1189 AQNTKLNESNVQLENKtscLKETQDQLLEsqkkekqlqeeaakLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAAT 1268
Cdd:PRK10929   95 PRSVPPNMSTDALEQE---ILQVSSQLLE--------------KSRQAQQEQDRAREISDSLSQLPQQQTEARRQLNEIE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1269 SQLDAQQATNKELQELLVKSqenegnLQGESLAVTEKLQQLE---------QANGELKEALCQKENglKELQGKLDESNT 1339
Cdd:PRK10929  158 RRLQTLGTPNTPLAQAQLTA------LQAESAALKALVDELElaqlsannrQELARLRSELAKKRS--QQLDAYLQALRN 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1340 VLESQKkshneiQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSL-QQKQLLLEKGNEFDTQLAEYQKV----- 1413
Cdd:PRK10929  230 QLNSQR------QREAERALESTELLAEQSGDLPKSIVAQFKINRELSQALnQQAQRMDLIASQQRQAASQTLQVrqaln 303

                         330       340
                  ....*....|....*....|....*.
gi 442628159 1414 -IDEMDDAASVKSALLEQLQNRVAEL 1438
Cdd:PRK10929  304 tLREQSQWLGVSNALGEALRAQVARL 329
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
306-854 1.45e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.14  E-value: 1.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  306 LREKQQHVEKLMVERDLDRE---DAQNQALQLQKNINELKARIVELESALDNERKKTEELQ------CSIDEAQFCGDEL 376
Cdd:PRK03918  219 LREELEKLEKEVKELEELKEeieELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEekvkelKELKEKAEEYIKL 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  377 NAQSQVYKEKIHDLESKITKLVSATPSLQSILppdlpSDDGALQEEIAKLQEKMtiqqKEVESRIAEqLEEEQRLRENVK 456
Cdd:PRK03918  299 SEFYEEYLDELREIEKRLSRLEEEINGIEERI-----KELEEKEERLEELKKKL----KELEKRLEE-LEERHELYEEAK 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  457 YLNEQIATLQSELvsKDEALEKFslsecgienlrrelellkEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATS 536
Cdd:PRK03918  369 AKKEELERLKKRL--TGLTPEKL------------------EKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAI 428

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  537 DSLESERvnktDECEILQTEvrMRDEQIRELnqqLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKtEKELVQS 616
Cdd:PRK03918  429 EELKKAK----GKCPVCGRE--LTEEHRKEL---LEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKK-ESELIKL 498

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  617 KEQAAKTLNDKEQLEK-QISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKqNELEDFQKKQSESEVHLQEIKA 695
Cdd:PRK03918  499 KELAEQLKELEEKLKKyNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELK-KKLAELEKKLDELEEELAELLK 577

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  696 QNTQKDFELVESGES-LKKLQ----QQLEQKTLGHEkLQAALEELKKEKETiIKEKEQELQQLQSKSAESESALKVVQVQ 770
Cdd:PRK03918  578 ELEELGFESVEELEErLKELEpfynEYLELKDAEKE-LEREEKELKKLEEE-LDKAFEELAETEKRLEELRKELEELEKK 655

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  771 -LEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANgSLEEEAKKSGHLLEQITKLK 849
Cdd:PRK03918  656 ySEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELE-KLEKALERVEELREKVKKYK 734


                  ....*
gi 442628159  850 SEVGE 854
Cdd:PRK03918  735 ALLKE 739
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 334-1418 1.71e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 53.13  E-value: 1.71e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   334 LQKNINELKArIVElESALDN--ERKKTEELQCSIDEAQfcgDEL-NAQSQVYKEKIHDLESKITKLVSATPSLQSILpp 410
Cdd:TIGR01612  673 IDALYNELSS-IVK-ENAIDNteDKAKLDDLKSKIDKEY---DKIqNMETATVELHLSNIENKKNELLDIIVEIKKHI-- 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   411 dlpsdDGALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRenvKYlNEQIATLQSELvskdealekfslsecgieNLR 490
Cdd:TIGR01612  746 -----HGEINKDLNKILEDFKNKEKELSNKINDYAKEKDELN---KY-KSKISEIKNHY------------------NDQ 798

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   491 RELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECeilQTEVRMRDEQIREL-NQ 569
Cdd:TIGR01612  799 INIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFINFENNC---KEKIDSEHEQFAELtNK 875

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   570 QLDEVT-TQLNVQKA---DSSALDDMLRLQKEGTEEKSTLLEKTEK--ELVQSKEQAAKTLNDK-----EQLEKQISDLK 638
Cdd:TIGR01612  876 IKAEISdDKLNDYEKkfnDSKSLINEINKSIEEEYQNINTLKKVDEyiKICENTKESIEKFHNKqnilkEILNKNIDTIK 955

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   639 QLAEQEKLVREMTENAINQIQLEKESIeqqlaLKQNELEDFQKKQSESEVHLQEIKAQ-NTQKDFELVESGESLKKLQQQ 717
Cdd:TIGR01612  956 ESNLIEKSYKDKFDNTLIDKINELDKA-----FKDASLNDYEAKNNELIKYFNDLKANlGKNKENMLYHQFDEKEKATND 1030

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   718 LEQKTlghEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESesalkvvQVQLEQLQQQAAASGEEGSKTVAKLHDEIS 797
Cdd:TIGR01612 1031 IEQKI---EDANKNIPNIEIAIHTSIYNIIDEIEKEIGKNIEL-------LNKEILEEAEINITNFNEIKEKLKHYNFDD 1100

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   798 QLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSghlleqitklksevgetqaalsschtdvESKTKQLEAAN 877
Cdd:TIGR01612 1101 FGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKS----------------------------ENYIDEIKAQI 1152

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   878 AALEKVnkeyaesrAEASDLQDKVKEITDTLHaELQAERSSSSALHTKLSKFSDEIATGHKELTSkadawsqemLQKEKE 957
Cdd:TIGR01612 1153 NDLEDV--------ADKAISNDDPEEIEKKIE-NIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTS---------LEEVKG 1214

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   958 LQeLRQQLQDSQDSQTKLKAEGERKE---KSFEESIKNLQEevTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEK 1034
Cdd:TIGR01612 1215 IN-LSYGKNLGKLFLEKIDEEKKKSEhmiKAMEAYIEDLDE--IKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHI 1291

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1035 MASEDAQKIADLKTLVEAIQVAN---ANISATNAELSTVLEVLQAEKSETN----HIFELFEMEADMNSERLIEKVTGIK 1107
Cdd:TIGR01612 1292 ISKKHDENISDIREKSLKIIEDFseeSDINDIKKELQKNLLDAQKHNSDINlylnEIANIYNILKLNKIKKIIDEVKEYT 1371

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1108 EELKETHLQLDERQKKFEELEEKLKQAQQSEQ-KLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSsi 1186
Cdd:TIGR01612 1372 KEIEENNKNIKDELDKSEKLIKKIKDDINLEEcKSKIESTLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADENN-- 1449

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1187 ieaQNTKLNESNVQL-ENKTSCLKETQ------------DQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKV 1253
Cdd:TIGR01612 1450 ---ENVLLLFKNIEMaDNKSQHILKIKkdnatndhdfniNELKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTEL 1526

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1254 EELVKVLEEKLQAATSQLDAQQATN--KELQELLV----KSQENEGNLQGESLAVTEKLQQLEQANgelkEALCQKENGL 1327
Cdd:TIGR01612 1527 LNKYSALAIKNKFAKTKKDSEIIIKeiKDAHKKFIleaeKSEQKIKEIKKEKFRIEDDAAKNDKSN----KAAIDIQLSL 1602

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1328 KELQGKLDESNTVlesqKKSHNEIQDKLEQAQQKERTLQEET--SKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDT 1405
Cdd:TIGR01612 1603 ENFENKFLKISDI----KKKINDCLKETESIEKKISSFSIDSqdTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELDE 1678

                         1130
                   ....*....|...
gi 442628159  1406 QLAEYQKVIDEMD 1418
Cdd:TIGR01612 1679 LDSEIEKIEIDVD 1691
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1074-1444 2.17e-06

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 52.20  E-value: 2.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1074 LQAEKSETNHIFELFEMeADMNSERLIEKVTGIKEELKETHLQLDERqkkFEELEEKLKQAQQSEQKLQQESQTSKEKLT 1153
Cdd:pfam07888   36 LEECLQERAELLQAQEA-ANRQREKEKERYKRDREQWERQRRELESR---VAELKEELRQSREKHEELEEKYKELSASSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1154 EIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLS 1233
Cdd:pfam07888  112 ELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLS 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1234 GELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKEL---QELLVKSQENEGNLqGESLAVTEKLQQLE 1310
Cdd:pfam07888  192 KEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELrslQERLNASERKVEGL-GEELSSMAAQRDRT 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1311 QAngELKEALCQkengLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERtlqeetSKLAEQLSQLKQANEELQKSL 1390
Cdd:pfam07888  271 QA--ELHQARLQ----AAQLTLQLADASLALREGRARWAQERETLQQSAEADK------DRIEKLSAELQRLEERLQEER 338

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 442628159  1391 QQKQLL-LEKGNEFD---TQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQ 1444
Cdd:pfam07888  339 MEREKLeVELGREKDcnrVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQ 396
PRK12704 PRK12704
phosphodiesterase; Provisional
 1073-1232 2.18e-06

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 52.09  E-value: 2.18e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1073 VLQAEKsETNHIFELFEMEADMNSErliEKVTGIKEELK----ETHLQLDERQKKFEELEEKLkqaQQSEQKLQQESqts 1148
Cdd:PRK12704   33 IKEAEE-EAKRILEEAKKEAEAIKK---EALLEAKEEIHklrnEFEKELRERRNELQKLEKRL---LQKEENLDRKL--- 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1149 kEKLTEIQQSLQELQDSVKQKEELVQNLEEKVREsssIIEAQNTKLNE-SNVQLEnktsclkETQDQLLESQKKEkqLQE 1227
Cdd:PRK12704  103 -ELLEKREEELEKKEKELEQKQQELEKKEEELEE---LIEEQLQELERiSGLTAE-------EAKEILLEKVEEE--ARH 169


                  ....*
gi 442628159 1228 EAAKL 1232
Cdd:PRK12704  170 EAAVL 174
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 301-1240 2.63e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.48  E-value: 2.63e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   301 SMQDLLREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALdneRKKTEELQCSIDEAQfcgDELNAQS 380
Cdd:pfam01576  187 AMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQL---AKKEEELQAALARLE---EETAQKN 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   381 QVYKeKIHDLESKITKLvsatpslqsilppdlpsddgalqeeiaklqekmtiqQKEVESRIAEQLEEEQRLRENVKYLNE 460
Cdd:pfam01576  261 NALK-KIRELEAQISEL------------------------------------QEDLESERAARNKAEKQRRDLGEELEA 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   461 QIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLE 540
Cdd:pfam01576  304 LKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALE 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   541 SERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLN-VQKADSSALDDMLRLQKEgTEEKSTLLEKTEKELVQSKEQ 619
Cdd:pfam01576  384 SENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSeSERQRAELAEKLSKLQSE-LESVSSLLNEAEGKNIKLSKD 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   620 AAktlndkeQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQnTQ 699
Cdd:pfam01576  463 VS-------SLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKK-LE 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   700 KDFELVESG-ESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQA 778
Cdd:pfam01576  535 EDAGTLEALeEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEK 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   779 AASgeegsktvAKLHDEISQLKSQAEETQSELKSTqsnleakSKQLEAANGSLEEeakksghLLEQITKLKSEVGEtqaa 858
Cdd:pfam01576  615 AIS--------ARYAEERDRAEAEAREKETRALSL-------ARALEEALEAKEE-------LERTNKQLRAEMED---- 668

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   859 LSSCHTDVESKTKQLEAANAALEkvnkeyaesrAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHK 938
Cdd:pfam01576  669 LVSSKDDVGKNVHELERSKRALE----------QQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQARDE 738

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   939 ELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTenlelstgTQTTIKDL 1018
Cdd:pfam01576  739 QGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKK--------LQAQMKDL 810

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1019 QERLEITNAELQHKEKMASEDAQKI----ADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFElfemeadm 1094
Cdd:pfam01576  811 QRELEEARASRDEILAQSKESEKKLknleAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQD-------- 882

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1095 NSERLIEKVTGIKEELKETHLQ---LDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKL----TEIQQSLQELQDSVK 1167
Cdd:pfam01576  883 EKRRLEARIAQLEEELEEEQSNtelLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLerqnKELKAKLQEMEGTVK 962

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 442628159  1168 QKEEL-VQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQ 1240
Cdd:pfam01576  963 SKFKSsIAALEAKIAQLEEQLEQESRERQAANKLVRRTEKKLKEVLLQVEDERRHADQYKDQAEKGNSRMKQLK 1036
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1120-1532 3.26e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.94  E-value: 3.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1120 RQKKFEELEEKLKQAQ----QSEQKL-------------------------QQESQ------TSKEKLTEIQQSLQELQD 1164
Cdd:TIGR04523   31 QDTEEKQLEKKLKTIKnelkNKEKELknldknlnkdeekinnsnnkikileQQIKDlndklkKNKDKINKLNSDLSKINS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1165 SVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANG 1244
Cdd:TIGR04523  111 EIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNID 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1245 DIKDSLVKVEELVKVLEEKLQ---AATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALC 1321
Cdd:TIGR04523  191 KIKNKLLKLELLLSNLKKKIQknkSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLS 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1322 QKENGLKELQGKLDESN----------TVLESQKKS--HNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKS 1389
Cdd:TIGR04523  271 EKQKELEQNNKKIKELEkqlnqlkseiSDLNNQKEQdwNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKE 350

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1390 LQQKQLlleKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDaqktaylETKELRRQLESLELE 1469
Cdd:TIGR04523  351 LTNSES---ENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEK-------LNQQKDEQIKKLQQE 420

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442628159  1470 KSrevLSLKAQMNGASSRSGKGDEVESLDIETSLAK--INFLNSIIADMQQKNDALKAKVQTLET 1532
Cdd:TIGR04523  421 KE---LLEKEIERLKETIIKNNSEIKDLTNQDSVKEliIKNLDNTRESLETQLKVLSRSINKIKQ 482
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 801-1027 3.27e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 3.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  801 SQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAAL 880
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  881 EKVNKEYAEsRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQE 960
Cdd:COG4942   100 EAQKEELAE-LLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 442628159  961 LRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNA 1027
Cdd:COG4942   179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
441-688 3.46e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.94  E-value: 3.46e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  441 IAEQLEEEQ-RLRENVKYLNEQIATLQSELVSKDEALEKFslsecgienlrrelelLKEENEKQAQEAQAEFTRKLAEKS 519
Cdd:COG3206   162 LEQNLELRReEARKALEFLEEQLPELRKELEEAEAALEEF----------------RQKNGLVDLSEEAKLLLQQLSELE 225

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  520 VEVLRLSSELQNLKATSDSLESERVNKTDECEILQTevrmrDEQIRELNQQLDEVTTQLNVQKADSSALD-DMLRLQKEG 598
Cdd:COG3206   226 SQLAEARAELAEAEARLAALRAQLGSGPDALPELLQ-----SPVIQQLRAQLAELEAELAELSARYTPNHpDVIALRAQI 300

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  599 TEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQeklvremtenaINQIQLEKESIEQQLALKQNELED 678
Cdd:COG3206   301 AALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAE-----------LPELEAELRRLEREVEVARELYES 369

                         250
                  ....*....|
gi 442628159  679 FQKKQSESEV 688
Cdd:COG3206   370 LLQRLEEARL 379
46 PHA02562
endonuclease subunit; Provisional
 1039-1255 3.73e-06

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 51.55  E-value: 3.73e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1039 DAQKIADLKTLVEA-IQVANANISATNAELSTVLEVLqaeKSETNHIFELfEMEADMNSERLIEKVTGIKEELKETHLQL 1117
Cdd:PHA02562  161 DISVLSEMDKLNKDkIRELNQQIQTLDMKIDHIQQQI---KTYNKNIEEQ-RKKNGENIARKQNKYDELVEEAKTIKAEI 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1118 DERQKKFEELEE----------KLKQAQ-------QSEQKL--------------QQESQTsKEKLTEIQQSLQELQDSV 1166
Cdd:PHA02562  237 EELTDELLNLVMdiedpsaalnKLNTAAakikskiEQFQKVikmyekggvcptctQQISEG-PDRITKIKDKLKELQHSL 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1167 KQKEELVQNLEEKVREsssiIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDI 1246
Cdd:PHA02562  316 EKLDTAIDELEEIMDE----FNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKI 391


                  ....*....
gi 442628159 1247 KDSLVKVEE 1255
Cdd:PHA02562  392 VKTKSELVK 400
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1100-1479 3.82e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.90  E-value: 3.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1100 IEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESqtskEKLTEIQQSLQELQDSVKQKEELVQNLEEK 1179
Cdd:pfam02463  144 IEIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELI----IDLEELKLQELKLKEQAKKALEYYQLKEKL 219

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1180 VRESSSIIEAQNTKLNESNvqlenktscLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKV 1259
Cdd:pfam02463  220 ELEEEYLLYLDYLKLNEER---------IDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKL 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1260 LEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNT 1339
Cdd:pfam02463  291 LAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQ 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1340 VLESQKKSHNEIQDKLEQAQ---QKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE 1416
Cdd:pfam02463  371 LEEELLAKKKLESERLSSAAklkEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEK 450

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442628159  1417 mddAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKA 1479
Cdd:pfam02463  451 ---EELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLK 510
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1127-1362 3.96e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.56  E-value: 3.96e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1127 LEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELqdsvKQKEELVqNLEEKVRESSSIIEAQNTKLNESNVQLENKTS 1206
Cdd:COG3206   166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEF----RQKNGLV-DLSEEAKLLLQQLSELESQLAEARAELAEAEA 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1207 CLKETQDQLLESQKKEKQLQEEAAkLSGELQQVQEANGDIKDSLVKVEE---LVKVLEEKLQAATSQLDAqqatnkELQE 1283
Cdd:COG3206   241 RLAALRAQLGSGPDALPELLQSPV-IQQLRAQLAELEAELAELSARYTPnhpDVIALRAQIAALRAQLQQ------EAQR 313

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 442628159 1284 LLVksqenegNLQGESLAVTEKLQQLEQANGELKEALcqkeNGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKE 1362
Cdd:COG3206   314 ILA-------SLEAELEALQAREASLQAQLAQLEARL----AELPELEAELRRLEREVEVARELYESLLQRLEEARLAE 381
46 PHA02562
endonuclease subunit; Provisional
 636-908 4.06e-06

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 51.55  E-value: 4.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  636 DLKQLAEQEKL----VREMTENaINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAqntqkdfELVESGESL 711
Cdd:PHA02562  161 DISVLSEMDKLnkdkIRELNQQ-IQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYD-------ELVEEAKTI 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  712 KklqQQLEQktlghekLQAALEELKKEKEtiikEKEQELQQLQSKSAESESALKVVQVQLEQLQQqaaasgeegsktvak 791
Cdd:PHA02562  233 K---AEIEE-------LTDELLNLVMDIE----DPSAALNKLNTAAAKIKSKIEQFQKVIKMYEK--------------- 283

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  792 lHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKsevgETQAALSSCHTDVESKTK 871
Cdd:PHA02562  284 -GGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLL----ELKNKISTNKQSLITLVD 358

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 442628159  872 QLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTL 908
Cdd:PHA02562  359 KAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTK 395
PRK09039 PRK09039
peptidoglycan -binding protein;
552-691 4.55e-06

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 50.73  E-value: 4.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  552 ILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDML-RLQKEgteekstlLEKTEKELVQSKEQAAKTLNDKEQL 630
Cdd:PRK09039   43 FLSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVaNLRAS--------LSAAEAERSRLQALLAELAGAGAAA 114

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442628159  631 EKQISDL-KQLAEQEKLvremTENAINQIQLEKESIEQ---QLALKQNELEDFQKKQSESEVHLQ 691
Cdd:PRK09039  115 EGRAGELaQELDSEKQV----SARALAQVELLNQQIAAlrrQLAALEAALDASEKRDRESQAKIA 175
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 975-1480 5.59e-06

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 51.28  E-value: 5.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   975 LKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQttikDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQ 1054
Cdd:pfam05557   14 LQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQ----ELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALN 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1055 VANANISATNAELSTVLEVLQAEKSETNHIFelfeMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQA 1134
Cdd:pfam05557   90 KKLNEKESQLADAREVISCLKNELSELRRQI----QRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSL 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1135 QQSEQKLQQESQ--TSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEaQNTKLNESNVQLENKTSCLKETQ 1212
Cdd:pfam05557  166 AEAEQRIKELEFeiQSQEQDSEIVKNSKSELARIPELEKELERLREHNKHLNENIE-NKLLLKEEVEDLKRKLEREEKYR 244

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1213 DQL----LESQKKEKQLQE-------------EAAKLSGELQQVQ-------EANGDIKDSLVKVEELVKVLEEKLQAAT 1268
Cdd:pfam05557  245 EEAatleLEKEKLEQELQSwvklaqdtglnlrSPEDLSRRIEQLQqreivlkEENSSLTSSARQLEKARRELEQELAQYL 324

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1269 SQLDAQQATNKELQELLVKSQE------NEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN---T 1339
Cdd:pfam05557  325 KKIEDLNKKLKRHKALVRRLQRrvllltKERDGYRAILESYDKELTMSNYSPQLLERIEEAEDMTQKMQAHNEEMEaqlS 404

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1340 VLESQKKSHNEIQDKLEQAQQ--KERTLQEETSKLAEQLSQLKQANEELQkslQQKQLLLEKGNEFDTQLA--EYQKVID 1415
Cdd:pfam05557  405 VAEEELGGYKQQAQTLERELQalRQQESLADPSYSKEEVDSLRRKLETLE---LERQRLREQKNELEMELErrCLQGDYD 481

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1416 E------------MDDAASVKSALLEQLQNRV-----------AELETALRQANDAQKTAYLETKELRRQLESLEL--EK 1470
Cdd:pfam05557  482 PkktkvlhlsmnpAAEAYQQRKNQLEKLQAEIerlkrllkkleDDLEQVLRLPETTSTMNFKEVLDLRKELESAELknQR 561

                          570
                   ....*....|
gi 442628159  1471 SREVLSLKAQ 1480
Cdd:pfam05557  562 LKEVFQAKIQ 571
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
602-1076 5.75e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.92  E-value: 5.75e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  602 KSTLLEKTEKELVQSKEQAAKTLNdKEQLEKQISDLKQLAEQEKLVREMTEN--AINQIQLEKESIEQQLALKQNELEDF 679
Cdd:COG4717    36 KSTLLAFIRAMLLERLEKEADELF-KPQGRKPELNLKELKELEEELKEAEEKeeEYAELQEELEELEEELEELEAELEEL 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  680 QKKQSESEVHLQeikaqntqkdfeLVESGESLKKLQQQLEQktlghekLQAALEELKkeketiikEKEQELQQLQSKSAE 759
Cdd:COG4717   115 REELEKLEKLLQ------------LLPLYQELEALEAELAE-------LPERLEELE--------ERLEELRELEEELEE 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  760 SESALKVVQVQLEQLQQQAAASGEEgskTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKsg 839
Cdd:COG4717   168 LEAELAELQEELEELLEQLSLATEE---ELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE-- 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  840 hllEQITKLKS--EVGETQAALSSCHTDVESKTKQLEAANAAL----------EKVNKEYAESRAEASDLQDKVKEITDT 907
Cdd:COG4717   243 ---ERLKEARLllLIAAALLALLGLGGSLLSLILTIAGVLFLVlgllallfllLAREKASLGKEAEELQALPALEELEEE 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  908 LHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQK--EKELQELRQQLQDSQDSQTKLKAEGERKEKS 985
Cdd:COG4717   320 ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEelEQEIAALLAEAGVEDEEELRAALEQAEEYQE 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  986 FEESIKNLQEEVTKAKTENLELSTGTQTTikDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQvANANISATNA 1065
Cdd:COG4717   400 LKEELEELEEQLEELLGELEELLEALDEE--ELEEELEELEEELEELEEELEELREELAELEAELEQLE-EDGELAELLQ 476

                         490
                  ....*....|.
gi 442628159 1066 ELSTVLEVLQA 1076
Cdd:COG4717   477 ELEELKAELRE 487
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
670-1160 5.79e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.92  E-value: 5.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  670 ALKQNELEDFQKKQSESEVHLQEIKAQNTQKDfELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKE-- 747
Cdd:COG4717    50 RLEKEADELFKPQGRKPELNLKELKELEEELK-EAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQll 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  748 ---QELQQLQSKSAESESALKVVqvqleqlqqqaaasgEEGSKTVAKLHDEISQLKSQAEETQSELKstqsnlEAKSKQL 824
Cdd:COG4717   129 plyQELEALEAELAELPERLEEL---------------EERLEELRELEEELEELEAELAELQEELE------ELLEQLS 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  825 EAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAAlEKVNKEYAESRAEAS--DLQDKVK 902
Cdd:COG4717   188 LATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE-ERLKEARLLLLIAAAllALLGLGG 266

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  903 EITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAegerk 982
Cdd:COG4717   267 SLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLE----- 341

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  983 eksFEESIKNLQEEVTKAKTENLELstgtqttikdLQERLEITNAELQHKEKMASED-----AQKIADLKTLVEAIQVAN 1057
Cdd:COG4717   342 ---LLDRIEELQELLREAEELEEEL----------QLEELEQEIAALLAEAGVEDEEelraaLEQAEEYQELKEELEELE 408

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1058 ANISATNAELSTVLEVLQAEKSETnhifELFEMEADMNS-----ERLIEKVTGIKEELK--ETHLQLDERQKKFEELEEK 1130
Cdd:COG4717   409 EQLEELLGELEELLEALDEEELEE----ELEELEEELEEleeelEELREELAELEAELEqlEEDGELAELLQELEELKAE 484

                         490       500       510
                  ....*....|....*....|....*....|
gi 442628159 1131 LKQAQQSEQKLQQESQTSKEKLTEIQQSLQ 1160
Cdd:COG4717   485 LRELAEEWAALKLALELLEEAREEYREERL 514
PRK11281 PRK11281
mechanosensitive channel MscK;
347-757 9.30e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 50.68  E-value: 9.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  347 ELESALD--NERKKTEE----LQCSIDEAQfcgdELNAQSQVYKEKIHDLESKITKlvsATPSLQSIlppdlpsddgalQ 420
Cdd:PRK11281   40 DVQAQLDalNKQKLLEAedklVQQDLEQTL----ALLDKIDRQKEETEQLKQQLAQ---APAKLRQA------------Q 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  421 EEIAKLQEKM---------TIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSelvskdealekfslsecgienlrr 491
Cdd:PRK11281  101 AELEALKDDNdeetretlsTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQT------------------------ 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  492 elellkeenekQAQEAQAEftrkLAEKSVEVLRLSSELQNLKATSDSLESERVNKtdeceiLQTEVRMRDEQIrELNQQL 571
Cdd:PRK11281  157 -----------QPERAQAA----LYANSQRLQQIRNLLKGGKVGGKALRPSQRVL------LQAEQALLNAQN-DLQRKS 214

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  572 DEVTTQLNvqkadssaldDMLRLQKEGTEEKSTLLEKT---------EKELVQSKEQAAKTLNDKE------------QL 630
Cdd:PRK11281  215 LEGNTQLQ----------DLLQKQRDYLTARIQRLEHQlqllqeainSKRLTLSEKTVQEAQSQDEaariqanplvaqEL 284

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  631 E--KQISD--------LKQLAEQEKLVREMTENAINQIQLEKESI--------------EQQLALKQNEL-EDFQKKQSE 685
Cdd:PRK11281  285 EinLQLSQrllkatekLNTLTQQNLRVKNWLDRLTQSERNIKEQIsvlkgslllsrilyQQQQALPSADLiEGLADRIAD 364

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  686 SEVHLQEIkaqNTQKDfELVESGESLKKLQQQleQKTLGHEKLQAALEELKKEKETIIKEKEQEL--------------Q 751
Cdd:PRK11281  365 LRLEQFEI---NQQRD-ALFQPDAYIDKLEAG--HKSEVTDEVRDALLQLLDERRELLDQLNKQLnnqlnlainlqlnqQ 438


                  ....*.
gi 442628159  752 QLQSKS 757
Cdd:PRK11281  439 QLLSVS 444
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 514-760 9.81e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 9.81e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  514 KLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLR 593
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  594 LQKEgteEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQeklvREMTENAINQIQLEKESIEQQLALKQ 673
Cdd:COG4942   101 AQKE---ELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPA----RREQAEELRADLAELAALRAELEAER 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  674 NELEDFQKKQSESEVHLQEIKAQNTQKdfelvesgesLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQL 753
Cdd:COG4942   174 AELEALLAELEEERAALEALKAERQKL----------LARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243


                  ....*..
gi 442628159  754 QSKSAES 760
Cdd:COG4942   244 PAAGFAA 250
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 397-645 9.89e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 9.89e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  397 LVSATPSLQSILPPDLPSDDGALQEEIAKLQEKMtiqqKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEAL 476
Cdd:COG4942    10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKEL----AALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAEL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  477 EKFSLSEcgienlrrelellkeeneKQAQEAQAEFTRKLAEKSVEVLRLS--SELQNLKATSDSLESERVNktdecEILQ 554
Cdd:COG4942    86 AELEKEI------------------AELRAELEAQKEELAELLRALYRLGrqPPLALLLSPEDFLDAVRRL-----QYLK 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  555 TEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKE-------GTEEKSTLLEKTEKELVQSKEQAAKTLNDK 627
Cdd:COG4942   143 YLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEeraaleaLKAERQKLLARLEKELAELAAELAELQQEA 222

                         250
                  ....*....|....*...
gi 442628159  628 EQLEKQISDLKQLAEQEK 645
Cdd:COG4942   223 EELEALIARLEAEAAAAA 240
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1208-1453 1.07e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 49.83  E-value: 1.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1208 LKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQAtnkELQELLVK 1287
Cdd:COG3883    18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERRE---ELGERARA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1288 SQENEGNLQgeslavteKLQQLEQANGelkealcqkengLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQE 1367
Cdd:COG3883    95 LYRSGGSVS--------YLDVLLGSES------------FSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1368 ETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQAND 1447
Cdd:COG3883   155 KLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAA 234


                  ....*.
gi 442628159 1448 AQKTAY 1453
Cdd:COG3883   235 AAAAAA 240
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 1087-1417 1.10e-05

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 49.85  E-value: 1.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1087 LFEMEADMNSERLIEkvtgIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQE----L 1162
Cdd:pfam06160   69 LFEAEELNDKYRFKK----AKKALDEIEELLDDIEEDIKQILEELDELLESEEKNREEVEELKDKYRELRKTLLAnrfsY 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1163 QDSVKQKEELVQNLEEK------VRESSSIIEAQNT--KLNESNVQLENKTS--------CLKETQDQLLESQKKEKQLQ 1226
Cdd:pfam06160  145 GPAIDELEKQLAEIEEEfsqfeeLTESGDYLEAREVleKLEEETDALEELMEdipplyeeLKTELPDQLEELKEGYREME 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1227 E-----EAAKLSGELQQVQEangDIKDSLVKVEEL-VKVLEEKLQAATSQLDAqqatnkeLQELLVKSQENEGNLQGESL 1300
Cdd:pfam06160  225 EegyalEHLNVDKEIQQLEE---QLEENLALLENLeLDEAEEALEEIEERIDQ-------LYDLLEKEVDAKKYVEKNLP 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1301 AVTEKLQQLEQANGELKE--ALCQKENGL--KELQgKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQL 1376
Cdd:pfam06160  295 EIEDYLEHAEEQNKELKEelERVQQSYTLneNELE-RVRGLEKQLEELEKRYDEIVERLEEKEVAYSELQEELEEILEQL 373

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 442628159  1377 SQLKQANEELQKSLQQkqllLEKGnEFDTQ--LAEYQKVIDEM 1417
Cdd:pfam06160  374 EEIEEEQEEFKESLQS----LRKD-ELEARekLDEFKLELREI 411
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1138-1394 1.18e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.02  E-value: 1.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1138 EQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLeekvRESSSIIEAQNtklnESNVQLENktscLKETQDQLLE 1217
Cdd:COG3206   163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEF----RQKNGLVDLSE----EAKLLLQQ----LSELESQLAE 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1218 SQKKEKQLQEEAAKLSGELQQVQEANGDIKDSlvkveELVKVLEEKLQAATSQLDAQQATNKElqellvksqenegnlqg 1297
Cdd:COG3206   231 ARAELAEAEARLAALRAQLGSGPDALPELLQS-----PVIQQLRAQLAELEAELAELSARYTP----------------- 288

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1298 ESLAVTEKLQQLEQANGELKEalcqkenglkELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEqLS 1377
Cdd:COG3206   289 NHPDVIALRAQIAALRAQLQQ----------EAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRR-LE 357

                         250
                  ....*....|....*..
gi 442628159 1378 QLKQANEELQKSLQQKQ 1394
Cdd:COG3206   358 REVEVARELYESLLQRL 374
CagA_N pfam18971
CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial ...
 1174-1456 1.45e-05

CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial virulence determinant and critical for gastric carcinogenesis. X-ray crystallographic analysis of the N-terminal CagA fragment (residues 1-876) revealed that the region has a structure comprised of three discrete domains. Domain I constitutes a mobile CagA N terminus, while Domain II tethers CagA to the plasma membrane by interacting with membrane phosphatidylserine. Domain III interacts intramolecularly with the intrinsically disordered C-terminal region, and this interaction potentiates the pathogenic scaffold/hub function of CagA.


Pssm-ID: 408741 [Multi-domain]  Cd Length: 876  Bit Score: 49.77  E-value: 1.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1174 QNLEEKvresssiIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQlqeeaAKLSGELQQVQEANGDIKDSLVKV 1253
Cdd:pfam18971  559 RNLENK-------LTAKGLSLQEANKLIKDFLSSNKELAGKALNFNKAVAE-----AKSTGNYDEVKKAQKDLEKSLRKR 626

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1254 EELVKVLEEKLQAAT---SQLDAQQATNKELQEL--LVKSQENEG--------NLQGESLAVTEKLQQLEQANGELKEAL 1320
Cdd:pfam18971  627 EHLEKEVEKKLESKSgnkNKMEAKAQANSQKDEIfaLINKEANRDaraiaytqNLKGIKRELSDKLEKISKDLKDFSKSF 706

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1321 CQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLqqKQLLLEkg 1400
Cdd:pfam18971  707 DEFKNGKNKDFSKAEETLKALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSV--KDVIIN-- 782

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442628159  1401 nefdtqlaeyQKVIDEMDD---AASVKSAL--LEQLQNRVAELETALRQ--ANDAQKTAYLET 1456
Cdd:pfam18971  783 ----------QKVTDKVDNlnqAVSVAKAMgdFSRVEQVLADLKNFSKEqlAQQAQKNEDFNT 835
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1127-1402 1.60e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 49.13  E-value: 1.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1127 LEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTS 1206
Cdd:COG4372    29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1207 CLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLV 1286
Cdd:COG4372   109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDEL 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1287 KSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQ 1366
Cdd:COG4372   189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 442628159 1367 EETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNE 1402
Cdd:COG4372   269 VEKDTEEEELEIAALELEALEEAALELKLLALLLNL 304
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
956-1392 1.85e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.38  E-value: 1.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  956 KELQELRQQLQDSQDSQTKLKAEGERKEKSfEESIKNLQEEVTKAKTENLELSTGTQttIKDLQERLEITNAELQHKEKM 1035
Cdd:COG4717    71 KELKELEEELKEAEEKEEEYAELQEELEEL-EEELEELEAELEELREELEKLEKLLQ--LLPLYQELEALEAELAELPER 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1036 ASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETnhifelfemeadmnSERLIEKVTGIKEELKETHL 1115
Cdd:COG4717   148 LEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEE--------------LQDLAEELEELQQRLAELEE 213

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1116 QLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQS-LQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKL 1194
Cdd:COG4717   214 ELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAaLLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLL 293

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1195 NESNVQLENKT------SCLKETQDQLLESQKKEKQLQ-----EEAAKLSGELQQVQEANGDIKDSL--VKVEELVKVLE 1261
Cdd:COG4717   294 AREKASLGKEAeelqalPALEELEEEELEELLAALGLPpdlspEELLELLDRIEELQELLREAEELEeeLQLEELEQEIA 373

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1262 EKLQAATS----QLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQAngELKEALCQKENGLKELQGKLDES 1337
Cdd:COG4717   374 ALLAEAGVedeeELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEE--ELEEELEELEEELEELEEELEEL 451

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 442628159 1338 NTVLES--QKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQ 1392
Cdd:COG4717   452 REELAEleAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREE 508
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
640-861 2.01e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 49.24  E-value: 2.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  640 LAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFqkKQSESEVHLQEIKAQNTQKdfelvesgesLKKLQQQLE 719
Cdd:COG3206   162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEF--RQKNGLVDLSEEAKLLLQQ----------LSELESQLA 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  720 QktlghekLQAALEELKKEKETIIKEKEQELQQLQSKSAESE-SALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQ 798
Cdd:COG3206   230 E-------ARAELAEAEARLAALRAQLGSGPDALPELLQSPViQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAA 302

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 442628159  799 LKSQ----AEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSS 861
Cdd:COG3206   303 LRAQlqqeAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYES 369
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 627-764 2.36e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 47.61  E-value: 2.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  627 KEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQS------ESEVHLQEIKAQNTQK 700
Cdd:COG1579    26 LKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGnvrnnkEYEALQKEIESLKRRI 105

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 442628159  701 DF---ELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAL 764
Cdd:COG1579   106 SDledEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKI 172
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1210-1378 2.73e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 47.23  E-value: 2.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1210 ETQDQLLESQKKEKQLQE---EAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELL- 1285
Cdd:COG1579     4 EDLRALLDLQELDSELDRlehRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLg 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1286 -VKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKshnEIQDKLEQAQQKERT 1364
Cdd:COG1579    84 nVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKA---ELDEELAELEAELEE 160

                         170
                  ....*....|....
gi 442628159 1365 LQEETSKLAEQLSQ 1378
Cdd:COG1579   161 LEAEREELAAKIPP 174
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1173-1482 2.97e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.96  E-value: 2.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1173 VQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAA-KLSGELQQVQEA----NGDIK 1247
Cdd:pfam15921   87 VKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRnQLQNTVHELEAAkclkEDMLE 166

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1248 DSLVKVEELVKVL---EEKLQAATSQL-DAQQATNKELQEllvksQENEGNLQGESL--AVTEKLQQLEQANGELKEALC 1321
Cdd:pfam15921  167 DSNTQIEQLRKMMlshEGVLQEIRSILvDFEEASGKKIYE-----HDSMSTMHFRSLgsAISKILRELDTEISYLKGRIF 241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1322 QKENGLKELQGkldESNTVLESQKKSHneiQDKLEQAQQKERTlqeETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGN 1401
Cdd:pfam15921  242 PVEDQLEALKS---ESQNKIELLLQQH---QDRIEQLISEHEV---EITGLTEKASSARSQANSIQSQLEIIQEQARNQN 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1402 E-FDTQLAEYQKVI----DEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESL--ELEKSREV 1474
Cdd:pfam15921  313 SmYMRQLSDLESTVsqlrSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLlaDLHKREKE 392


                   ....*...
gi 442628159  1475 LSLKAQMN 1482
Cdd:pfam15921  393 LSLEKEQN 400
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
1108-1395 3.15e-05

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 47.60  E-value: 3.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1108 EELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSII 1187
Cdd:COG1340     1 SKTDELSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEER 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1188 EAQNTKLNESNVQLENktscLKETQDQLLESQKKEKQLQEEAAKLSGElQQVQEANGDIKDSLVkveELVKVLEEKLQAA 1267
Cdd:COG1340    81 DELNEKLNELREELDE----LRKELAELNKAGGSIDKLRKEIERLEWR-QQTEVLSPEEEKELV---EKIKELEKELEKA 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1268 TSQLDAqqatNKELQELLvksqenegnlqGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKS 1347
Cdd:COG1340   153 KKALEK----NEKLKELR-----------AELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKE 217

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 442628159 1348 HNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQL 1395
Cdd:COG1340   218 IVEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKEEL 265
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1003-1484 3.53e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.68  E-value: 3.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1003 ENLELSTGTQ-TTIKDLQERLEITNAE--LQHKEKMASEDAQKIADLKTlVEAIQVANA--------NISATNAELSTVL 1071
Cdd:pfam12128  149 QNDRTLLGRErVELRSLARQFALCDSEspLRHIDKIAKAMHSKEGKFRD-VKSMIVAILeddgvvppKSRLNRQQVEHWI 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1072 EVLQAEKSETNHIFELFEMEADMNS-ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQaqqseqKLQQESQTSKE 1150
Cdd:pfam12128  228 RDIQAIAGIMKIRPEFTKLQQEFNTlESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQ------LLRTLDDQWKE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1151 KLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIiEAQNTKLNESNV-QLENKTSCLKETQDQLLESQ---------K 1220
Cdd:pfam12128  302 KRDELNGELSAADAAVAKDRSELEALEDQHGAFLDA-DIETAAADQEQLpSWQSELENLEERLKALTGKHqdvtakynrR 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1221 KEKQLQEEAAKLSGeLQQVQEANGDIKDSLVKVEElvKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESL 1300
Cdd:pfam12128  381 RSKIKEQNNRDIAG-IKDKLAKIREARDRQLAVAE--DDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQAT 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1301 AVTEKLQQLEQANGEL---KEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQL- 1376
Cdd:pfam12128  458 ATPELLLQLENFDERIeraREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLl 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1377 ----SQLKQANEELQKSLQQKQLLlekgnefdtqlaeyQKVIDEMDDAASVKSAL--------LEQLQ-NRVAELETALR 1443
Cdd:pfam12128  538 hflrKEAPDWEQSIGKVISPELLH--------------RTDLDPEVWDGSVGGELnlygvkldLKRIDvPEWAASEEELR 603

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|.
gi 442628159  1444 QANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMNGA 1484
Cdd:pfam12128  604 ERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFA 644
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 515-851 3.66e-05

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 48.66  E-value: 3.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   515 LAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRL 594
Cdd:pfam10174  361 LNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTT 440

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   595 QKEGTEEKSTLLEKTEKELVQSKEQAAKTLndkEQLEKQISDLKQ--------LAEQEKLVREMTENAINQIQlekESIE 666
Cdd:pfam10174  441 LEEALSEKERIIERLKEQREREDRERLEEL---ESLKKENKDLKEkvsalqpeLTEKESSLIDLKEHASSLAS---SGLK 514

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   667 QQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFEL-VESGESLKKLQQQLEQKTLGHEKLQAALEEL---------- 735
Cdd:pfam10174  515 KDSKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVRTnPEINDRIRLLEQEVARYKEESGKAQAEVERLlgilrevene 594

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   736 KKEKETIIKE---------KEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEET 806
Cdd:pfam10174  595 KNDKDKKIAElesltlrqmKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQLEELMGALEKTRQELDAT 674

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 442628159   807 QSELKSTQSNLEAKSKQLEaangSLEEEAKKSghlLEQITKLKSE 851
Cdd:pfam10174  675 KARLSSTQQSLAEKDGHLT----NLRAERRKQ---LEEILEMKQE 712
PRK12704 PRK12704
phosphodiesterase; Provisional
 1102-1286 3.95e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 48.24  E-value: 3.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1102 KVTGIKEELKEThlqLDERQKKFEEL-EEKLKQAQQSEQKLQQE-SQTSKEKLTEIQQslqeLQDSVKQKEELVQNLEEK 1179
Cdd:PRK12704   32 KIKEAEEEAKRI---LEEAKKEAEAIkKEALLEAKEEIHKLRNEfEKELRERRNELQK----LEKRLLQKEENLDRKLEL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1180 VRESSSIIEAQNTKLNESNVQLENKtsclKETQDQLLESQKKEkqlQEEAAKLSGElqqvqEANgdikdslvkvEELVKV 1259
Cdd:PRK12704  105 LEKREEELEKKEKELEQKQQELEKK----EEELEELIEEQLQE---LERISGLTAE-----EAK----------EILLEK 162

                         170       180       190
                  ....*....|....*....|....*....|...
gi 442628159 1260 LEEKLQAATSQL------DAQQATNKELQELLV 1286
Cdd:PRK12704  163 VEEEARHEAAVLikeieeEAKEEADKKAKEILA 195
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
592-1023 5.00e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 5.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  592 LRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKEsiEQQLAL 671
Cdd:COG4717    83 AEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEER--LEELRE 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  672 KQNELEDFQKKQSESEVHLQEIKAQNT-QKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKE--Q 748
Cdd:COG4717   161 LEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEaaA 240

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  749 ELQQLQSK--SAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEA 826
Cdd:COG4717   241 LEERLKEArlLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEE 320

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  827 ANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVES-KTKQLEAANAALEK----VNKEYAESRAEASDLQDKV 901
Cdd:COG4717   321 LEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEElQLEELEQEIAALLAeagvEDEEELRAALEQAEEYQEL 400

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  902 KEITDTLHAELQAERSSSSALHTKLSKfsDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGER 981
Cdd:COG4717   401 KEELEELEEQLEELLGELEELLEALDE--EELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQEL 478

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 442628159  982 KEKsfEESIKNLQEEVTKAKTenlelstgTQTTIKDLQERLE 1023
Cdd:COG4717   479 EEL--KAELRELAEEWAALKL--------ALELLEEAREEYR 510
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1036-1277 5.44e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 5.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1036 ASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQaeksetnhifelfemEADMNSERLIEKVTGIKEELKETHL 1115
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA---------------ALERRIAALARRIRALEQELAALEA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1116 QLDERQKKFEELEEKLKQAQQSEQK----LQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVREsssiIEAQN 1191
Cdd:COG4942    84 ELAELEKEIAELRAELEAQKEELAEllraLYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEE----LRADL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1192 TKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQL 1271
Cdd:COG4942   160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239


                  ....*.
gi 442628159 1272 DAQQAT 1277
Cdd:COG4942   240 AERTPA 245
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
326-525 6.67e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.99  E-value: 6.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  326 DAQNQALQLQKNINELKARIVELES---ALDNERKKTEELQCSIDE-AQFCGDELNAQSqvYKEKIHDLESKITKLVSAT 401
Cdd:COG4913   607 DNRAKLAALEAELAELEEELAEAEErleALEAELDALQERREALQRlAEYSWDEIDVAS--AEREIAELEAELERLDASS 684

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  402 PSLQsilppdlpsddgALQEEIAKLQEkmtiQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSL 481
Cdd:COG4913   685 DDLA------------ALEEQLEELEA----ELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR 748

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 442628159  482 SECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRL 525
Cdd:COG4913   749 ALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERA 792
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 620-827 6.70e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 6.70e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  620 AAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQ 699
Cdd:COG4942    15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  700 KDFELVESGESLKKL------------------QQQLEQKTLGHEKLQAALEELKKEKETIIKEKEqELQQLQSKSAESE 761
Cdd:COG4942    95 LRAELEAQKEELAELlralyrlgrqpplalllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLA-ELAALRAELEAER 173

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 442628159  762 SALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAA 827
Cdd:COG4942   174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
46 PHA02562
endonuclease subunit; Provisional
 1014-1252 6.92e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 47.32  E-value: 6.92e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1014 TIKDLQERLE-ITNAELQHKEKMASEDAQKIADLKTLVEAIQVAnanisatnaelstVLEVLQAEKSETNHIFELFEMEA 1092
Cdd:PHA02562  199 TYNKNIEEQRkKNGENIARKQNKYDELVEEAKTIKAEIEELTDE-------------LLNLVMDIEDPSAALNKLNTAAA 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1093 DMNSErlIEKVTGIKEELKETHL------QLDERQKKFEELEEKLKQAQQSEQKL---QQESQTSKEKLTEIQQSLQELQ 1163
Cdd:PHA02562  266 KIKSK--IEQFQKVIKMYEKGGVcptctqQISEGPDRITKIKDKLKELQHSLEKLdtaIDELEEIMDEFNEQSKKLLELK 343

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1164 DSVKQKEELVQNLEEKVRESSSIIEaqntKLNESNVqleNKTSCLKETQDQLlesqkkeKQLQEEAAKLSGELQQVQEAN 1243
Cdd:PHA02562  344 NKISTNKQSLITLVDKAKKVKAAIE----ELQAEFV---DNAEELAKLQDEL-------DKIVKTKSELVKEKYHRGIVT 409


                  ....*....
gi 442628159 1244 GDIKDSLVK 1252
Cdd:PHA02562  410 DLLKDSGIK 418
PLN02939 PLN02939
transferase, transferring glycosyl groups
 999-1355 7.12e-05

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 47.59  E-value: 7.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  999 KAKTENLELSTGTQTTIKDLQERLEiTNAELQHKEKMASEDAQKIADlkTLVEAIQVANANISATNAELSTVLEVLQAEK 1078
Cdd:PLN02939   36 RARRRGFSSQQKKKRGKNIAPKQRS-SNSKLQSNTDENGQLENTSLR--TVMELPQKSTSSDDDHNRASMQRDEAIAAID 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1079 SETNHIFELFEMEADMNSERLIEKvtgIKEELKETHLQLDERQKKFEELEEKLKQaqqsEQKLQQESQTSKEKLTEIQQS 1158
Cdd:PLN02939  113 NEQQTNSKDGEQLSDFQLEDLVGM---IQNAEKNILLLNQARLQALEDLEKILTE----KEALQGKINILEMRLSETDAR 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1159 LQeLQDSVKQKEELVQNLEEKVRESSSIIEAQN-----------TKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQE 1227
Cdd:PLN02939  186 IK-LAAQEKIHVEILEEQLEKLRNELLIRGATEglcvhslskelDVLKEENMLLKDDIQFLKAELIEVAETEERVFKLEK 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1228 EAAKLSGELQQVQ----EANGDI-KDSLVKVE---ELVKVLEEKLQAATSQLDAQQAT---NKELQELLVKSQEN--EGN 1294
Cdd:PLN02939  265 ERSLLDASLRELEskfiVAQEDVsKLSPLQYDcwwEKVENLQDLLDRATNQVEKAALVldqNQDLRDKVDKLEASlkEAN 344

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 442628159 1295 LQGESLAVTEKLQQ--------LEQANGELKEALCQKENGLKELQGKLdeSNTVLESQKKSHNEIQDKL 1355
Cdd:PLN02939  345 VSKFSSYKVELLQQklklleerLQASDHEIHSYIQLYQESIKEFQDTL--SKLKEESKKRSLEHPADDM 411
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 594-1389 8.82e-05

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 47.52  E-value: 8.82e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  594 LQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLaeqeklvremtENAINQIQLEKESIEQQLALKQ 673
Cdd:PTZ00440  839 LQKFPTEDENLNLKELEKEFNENNQIVDNIIKDIENMNKNINIIKTL-----------NIAINRSNSNKQLVEHLLNNKI 907

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  674 NELEDFQKkqsesevHLQEIKAQN----TQKDFELVESGESLKKLQQQLEQKTLGHEKLQA--ALEELKKEKETIIKEKE 747
Cdd:PTZ00440  908 DLKNKLEQ-------HMKIINTDNiiqkNEKLNLLNNLNKEKEKIEKQLSDTKINNLKMQIekTLEYYDKSKENINGNDG 980

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  748 QELQQLQSKSAESEsALKVVQVQLEQLQQQAAASGEEgskTVAKLHDEISQLksqaeeTQSELKSTQSNLEAKSKQLEAa 827
Cdd:PTZ00440  981 THLEKLDKEKDEWE-HFKSEIDKLNVNYNILNKKIDD---LIKKQHDDIIEL------IDKLIKEKGKEIEEKVDQYIS- 1049

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  828 ngSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEItdt 907
Cdd:PTZ00440 1050 --LLEKMKTKLSSFHFNIDIKKYKNPKIKEEIKLLEEKVEALLKKIDENKNKLIEIKNKSHEHVVNADKEKNKQTEH--- 1124

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  908 lhaeLQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFE 987
Cdd:PTZ00440 1125 ----YNKKKKSLEKIYKQMEKTLKELENMNLEDITLNEVNEIEIEYERILIDHIVEQINNEAKKSKTIMEEIESYKKDID 1200

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  988 ESIKNLQEEvTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKmaSEDAQKIADLKT--------LVEAIQVANAn 1059
Cdd:PTZ00440 1201 QVKKNMSKE-RNDHLTTFEYNAYYDKATASYENIEELTTEAKGLKGE--ANRSTNVDELKEiklqvfsyLQQVIKENNK- 1276

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1060 ISATNAELSTVLEVLQAEKSET------NHIFELFEMEADMNSErlIEKVTGIKEELKETHLQLDERQKKFEELEEKlKQ 1133
Cdd:PTZ00440 1277 MENALHEIKNMYEFLISIDSEKilkeilNSTKKAEEFSNDAKKE--LEKTDNLIKQVEAKIEQAKEHKNKIYGSLED-KQ 1353

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1134 AQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEE-KVRESSSIIEAQNTKLNESNVQLENKTSCLKETQ 1212
Cdd:PTZ00440 1354 IDDEIKKIEQIKEEISNKRKEINKYLSNIKSNKEKCDLHVRNASRgKDKIDFLNKHEAIEPSNSKEVNIIKITDNINKCK 1433

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1213 DQLLESQKKEKQLQEEAAKLsgeLQQVQEANGDIKDSLVKVEElvKVLEEKLQAATSQLDAQQATNKELQELLVKSQENE 1292
Cdd:PTZ00440 1434 QYSNEAMETENKADENNDSI---IKYEKEITNILNNSSILGKK--TKLEKKKKEATNIMDDINGEHSIIKTKLTKSSEKL 1508

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1293 GNLQ--------GESLA---VTEKLQQLEQANGELKEALCQKENGLKELQ----------------GKLDESNTvLESQK 1345
Cdd:PTZ00440 1509 NQLNeqpnikreGDVLNndkSTIAYETIQYNLGRVKHNLLNILNIKDEIEtilnkaqdlmrdiskiSKIVENKN-LENLN 1587

                         810       820       830       840
                  ....*....|....*....|....*....|....*....|....
gi 442628159 1346 KSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKS 1389
Cdd:PTZ00440 1588 DKEADYVKYLDNILKEKQLMEAEYKKLNEIYSDVDNIEKELKKH 1631
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1554-1571 9.17e-05

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.91  E-value: 9.17e-05
                           10
                   ....*....|....*...
gi 442628159  1554 RLFCDICDEFDqHDTEDC 1571
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1115-1306 9.70e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.69  E-value: 9.70e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1115 LQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSsiiEAQNTKL 1194
Cdd:COG1579    10 LDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYE---EQLGNVR 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1195 NESNVQlenktSCLKEtqdqlLESQKKEKQLQEEaaklsgELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQ 1274
Cdd:COG1579    87 NNKEYE-----ALQKE-----IESLKRRISDLED------EILELMERIEELEEELAELEAELAELEAELEEKKAELDEE 150

                         170       180       190
                  ....*....|....*....|....*....|...
gi 442628159 1275 QA-TNKELQELLVKSQENEGNLQGESLAVTEKL 1306
Cdd:COG1579   151 LAeLEAELEELEAEREELAAKIPPELLALYERI 183
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 629-765 9.97e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.69  E-value: 9.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  629 QLEKQISDL-KQLAEQEKLVREMtENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKaqnTQKDFELVES 707
Cdd:COG1579    21 RLEHRLKELpAELAELEDELAAL-EARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVR---NNKEYEALQK 96

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442628159  708 G-ESLKKLQQQLEQKTLGH----EKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALK 765
Cdd:COG1579    97 EiESLKRRISDLEDEILELmeriEELEEELAELEAELAELEAELEEKKAELDEELAELEAELE 159
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 702-1329 1.05e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 47.02  E-value: 1.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   702 FELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAAS 781
Cdd:pfam05483  215 FKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   782 GEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSleeeakKSGHLLeQITKLKSEVGETQAALSS 861
Cdd:pfam05483  295 TKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKA------KAAHSF-VVTEFEATTCSLEELLRT 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   862 CHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLhaelqAERSSSSALHTKLSKFSDEIATGHKELT 941
Cdd:pfam05483  368 EQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKIL-----AEDEKLLDEKKQFEKIAEELKGKEQELI 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   942 SKADAwsqemlqKEKELQELRQQLQDSQDSqtklkaegerkEKSFEESIKNLQEEVTKAKTENLELSTGtqttikdlqer 1021
Cdd:pfam05483  443 FLLQA-------REKEIHDLEIQLTAIKTS-----------EEHYLKEVEDLKTELEKEKLKNIELTAH----------- 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1022 leiTNAELQHKEKMASEDAQKIADLKTLVEAIqvananISATNAELSTVLEVLQAEKSETNhifelFEMEADMNSERLIE 1101
Cdd:pfam05483  494 ---CDKLLLENKELTQEASDMTLELKKHQEDI------INCKKQEERMLKQIENLEEKEMN-----LRDELESVREEFIQ 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1102 KVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVR 1181
Cdd:pfam05483  560 KGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVN 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1182 ESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQqvQEANGDIKDSLVKVEELVKVLE 1261
Cdd:pfam05483  640 KLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEID--KRCQHKIAEMVALMEKHKHQYD 717

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442628159  1262 EKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKE 1329
Cdd:pfam05483  718 KIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKD 785
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1147-1464 1.19e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.84  E-value: 1.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1147 TSKEKLTEIQQSLQELQdsvkqkeeLVQnLEEKVRESSSiieAQNTKLNESNVQLENKTSCLKetqdQLLESQKKEKQLQ 1226
Cdd:PRK05771   13 TLKSYKDEVLEALHELG--------VVH-IEDLKEELSN---ERLRKLRSLLTKLSEALDKLR----SYLPKLNPLREEK 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1227 EEAAKLSGElqqvqEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQ-----ELLVKSQENEGNLQGESLA 1301
Cdd:PRK05771   77 KKVSVKSLE-----ELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEpwgnfDLDLSLLLGFKYVSVFVGT 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1302 VTEKLQQLEQANGELKEALCQKENGLKE------LQGKLDESNTVLESQKKSHNEIQDkleqaqqkERTLQEETSKLAEQ 1375
Cdd:PRK05771  152 VPEDKLEELKLESDVENVEYISTDKGYVyvvvvvLKELSDEVEEELKKLGFERLELEE--------EGTPSELIREIKEE 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1376 LSQLKQANEELQKSLqqkqlllekgNEFDTQLAEYQKVIDEMDDAASVKSALLEQL--------------QNRVAELETA 1441
Cdd:PRK05771  224 LEEIEKERESLLEEL----------KELAKKYLEELLALYEYLEIELERAEALSKFlktdktfaiegwvpEDRVKKLKEL 293

                         330       340
                  ....*....|....*....|...
gi 442628159 1442 LRQANDaqKTAYLETKELRRQLE 1464
Cdd:PRK05771  294 IDKATG--GSAYVEFVEPDEEEE 314
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
306-738 1.32e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.98  E-value: 1.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  306 LREKQQHVEKlMVERDLDREDAQNQALQLQKNINELKAR-----IVELESALDNERKKTEELQCSIDEaqfcgdelnaqs 380
Cdd:PRK03918  343 LKKKLKELEK-RLEELEERHELYEEAKAKKEELERLKKRltgltPEKLEKELEELEKAKEEIEEEISK------------ 409

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  381 qvYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDGALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLnE 460
Cdd:PRK03918  410 --ITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELREL-E 486

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  461 QIATLQSELVSKDEALEKfslsecgIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSEL---QNLKATSD 537
Cdd:PRK03918  487 KVLKKESELIKLKELAEQ-------LKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELeklEELKKKLA 559

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  538 SLESERVNKTDECEILQTEVRMRD-EQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEgteekstlLEKTEKELVQS 616
Cdd:PRK03918  560 ELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPFYNEYLELKDAEKELEREEKE--------LKKLEEELDKA 631

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  617 KEQAAKTLNDKEQLEKQISDLKQLAEQEKLVRemtenainqIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQ 696
Cdd:PRK03918  632 FEELAETEKRLEELRKELEELEKKYSEEEYEE---------LREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEE 702

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 442628159  697 NTqkdfELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKE 738
Cdd:PRK03918  703 LE----EREKAKKELEKLEKALERVEELREKVKKYKALLKER 740
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 305-904 1.53e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 46.58  E-value: 1.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   305 LLREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVE--LESALDNERKKTEELQCSIDEAQFCGDELNAQSQV 382
Cdd:TIGR00606  369 LIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAqlCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEI 448

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   383 YKEKIHDLESKITKLVSATPSLQSILppdlpsddgalqeeiaKLQEKMTiqQKEVESRIAEQLEEEQRLRENVKYLNEQI 462
Cdd:TIGR00606  449 LEKKQEELKFVIKELQQLEGSSDRIL----------------ELDQELR--KAERELSKAEKNSLTETLKKEVKSLQNEK 510

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   463 ATLQSELVSKDEALEKfslsecgiENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESE 542
Cdd:TIGR00606  511 ADLDRKLRKLDQEMEQ--------LNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSK 582

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   543 RVnktdecEILQTEVRMRDEQ--IRELNQQLDEVTTQLNVQKADSSALDDMLrLQKEGTEEKSTLLEKTEKELVQSKEQA 620
Cdd:TIGR00606  583 SK------EINQTRDRLAKLNkeLASLEQNKNHINNELESKEEQLSSYEDKL-FDVCGSQDEESDLERLKEEIEKSSKQR 655

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   621 AKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQK 700
Cdd:TIGR00606  656 AMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGR 735

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   701 DFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQE---------LQQLQSKSAESESalKVVQVQL 771
Cdd:TIGR00606  736 QSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAkvcltdvtiMERFQMELKDVER--KIAQQAA 813

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   772 EQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQ---SNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKL 848
Cdd:TIGR00606  814 KLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQeqiQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVEL 893

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   849 KSEVGETQAALSSCHT----DVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEI 904
Cdd:TIGR00606  894 STEVQSLIREIKDAKEqdspLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNI 953
PRK11281 PRK11281
mechanosensitive channel MscK;
602-849 1.59e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 46.44  E-value: 1.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  602 KSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQ-LAEQEKLVREMTEN---------AINQIQLEKESI---EQQ 668
Cdd:PRK11281   50 KQKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQqLAQAPAKLRQAQAElealkddndEETRETLSTLSLrqlESR 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  669 LALKQNELEDFQKK-----------QSESE----------VHLQEIKAQ-NTQKDFELVESGESLKKLQQQL-------- 718
Cdd:PRK11281  130 LAQTLDQLQNAQNDlaeynsqlvslQTQPEraqaalyansQRLQQIRNLlKGGKVGGKALRPSQRVLLQAEQallnaqnd 209

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  719 -EQKTL-GHEKLQAALEELKKEKETIIKEKEQELQQLQskSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAK---LH 793
Cdd:PRK11281  210 lQRKSLeGNTQLQDLLQKQRDYLTARIQRLEHQLQLLQ--EAINSKRLTLSEKTVQEAQSQDEAARIQANPLVAQeleIN 287

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 442628159  794 DEISQLKSQAEETQSELksTQSNLEAKSkQLEAANGSleEEAKKsghllEQITKLK 849
Cdd:PRK11281  288 LQLSQRLLKATEKLNTL--TQQNLRVKN-WLDRLTQS--ERNIK-----EQISVLK 333
PRK11281 PRK11281
mechanosensitive channel MscK;
909-1446 1.70e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 46.44  E-value: 1.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  909 HAELQAERSSSSALHTKLSKFSDeiatghKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEE 988
Cdd:PRK11281   28 RAASNGDLPTEADVQAQLDALNK------QKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  989 SIKNLQEEVTKAKTENLElstgtQTTIKDLQERLEITNAELQhkekmaseDAQkiadlktlvEAIQVANANISAtnaeLS 1068
Cdd:PRK11281  102 ELEALKDDNDEETRETLS-----TLSLRQLESRLAQTLDQLQ--------NAQ---------NDLAEYNSQLVS----LQ 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1069 TVLEVLQAEKSEtnhifelfemeadmNSERLiekvtgikeelkethlqlderqkkfEELEEKLKQAQQSEQKLQQESQTs 1148
Cdd:PRK11281  156 TQPERAQAALYA--------------NSQRL-------------------------QQIRNLLKGGKVGGKALRPSQRV- 195

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1149 kekLTEIQQSLQELQDSVKQKE----ELVQNLEEKVREsssiieaqntKLNESNVQLEnktsclKETQD-QLLESQKKEK 1223
Cdd:PRK11281  196 ---LLQAEQALLNAQNDLQRKSlegnTQLQDLLQKQRD----------YLTARIQRLE------HQLQLlQEAINSKRLT 256

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1224 QLQEEAAklsgELQQVQEANGDIKDSLVKveelvkvleeklqaatsqldAQQATNKELQELLVKSqenegnlqgeslavT 1303
Cdd:PRK11281  257 LSEKTVQ----EAQSQDEAARIQANPLVA--------------------QELEINLQLSQRLLKA--------------T 298

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1304 EKLQQLEQANGELK---EALCQKENGLKE----LQGKLdesntVLesqkkshNEIqdkLEQAQQKERTLQeETSKLAEQL 1376
Cdd:PRK11281  299 EKLNTLTQQNLRVKnwlDRLTQSERNIKEqisvLKGSL-----LL-------SRI---LYQQQQALPSAD-LIEGLADRI 362

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1377 SQLKQAneelQKSLQQKQLLLEKGNEFDTQLAEYQKVidEMDDAasVKSALLEQLQNRVAELETALRQAN 1446
Cdd:PRK11281  363 ADLRLE----QFEINQQRDALFQPDAYIDKLEAGHKS--EVTDE--VRDALLQLLDERRELLDQLNKQLN 424
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1123-1470 1.78e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 46.58  E-value: 1.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1123 KFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKeelvQNLEEKVRESSSIIEAQNTKLNESNVQLE 1202
Cdd:TIGR00606  183 RYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSK----EAQLESSREIVKSYENELDPLKNRLKEIE 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1203 NKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQV-QEANGDIKDSLVKVEELVKVLEEKLQAATSQLDA----QQAT 1277
Cdd:TIGR00606  259 HNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVfQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKlnkeRRLL 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1278 NKELQELLVK------------SQENEGNLQGESLAVTEKLQQLEQ---ANGELKEALCQKENGLKELQGKLDESNTVLE 1342
Cdd:TIGR00606  339 NQEKTELLVEqgrlqlqadrhqEHIRARDSLIQSLATRLELDGFERgpfSERQIKNFHTLVIERQEDEAKTAAQLCADLQ 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1343 SQKKSHNEIQDKLE-QAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVidEMDDAA 1421
Cdd:TIGR00606  419 SKERLKQEQADEIRdEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKA--EKNSLT 496

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 442628159  1422 SVKSALLEQLQNRVAELETALRQanDAQKTAYLE-TKELRRQLESLELEK 1470
Cdd:TIGR00606  497 ETLKKEVKSLQNEKADLDRKLRK--LDQEMEQLNhHTTTRTQMEMLTKDK 544
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
841-1445 1.84e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 1.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  841 LLEQITKLKSEVGEtqaaLSSCHTDVESKTKQLEAAnAALEKVNKEYAESRAEASDLQD--------KVKEITDTLHAEL 912
Cdd:COG4913   223 TFEAADALVEHFDD----LERAHEALEDAREQIELL-EPIRELAERYAAARERLAELEYlraalrlwFAQRRLELLEAEL 297

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  913 QAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLqdsqdsqTKLKAEGERKEKSFEESIKN 992
Cdd:COG4913   298 EELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERL-------ERELEERERRRARLEALLAA 370

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  993 LQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVL- 1071
Cdd:COG4913   371 LGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALa 450

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1072 EVLQAEKSETNHIFELFEMEADMNS-----ERLI--------------EKVTGIKEELK-ETHLQLderqkkfeeleEKL 1131
Cdd:COG4913   451 EALGLDEAELPFVGELIEVRPEEERwrgaiERVLggfaltllvppehyAAALRWVNRLHlRGRLVY-----------ERV 519

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1132 KQAQQSEQKLQQESQTSKEKLT--------EIQQSLQELQDSVKqkeelVQNLEEKVRESSSI-IEAQ------------ 1190
Cdd:COG4913   520 RTGLPDPERPRLDPDSLAGKLDfkphpfraWLEAELGRRFDYVC-----VDSPEELRRHPRAItRAGQvkgngtrhekdd 594

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1191 NTKLNESNV-------QLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSG---ELQQVQEANGDIKDslvkveelVKVL 1260
Cdd:COG4913   595 RRRIRSRYVlgfdnraKLAALEAELAELEEELAEAEERLEALEAELDALQErreALQRLAEYSWDEID--------VASA 666

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1261 EEKLQAATSQLDAQQATNKELQELlvksQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDE---- 1336
Cdd:COG4913   667 EREIAELEAELERLDASSDDLAAL----EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaedl 742

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1337 --SNTVLESQKKSHNEIQDKLEqaQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLekGNEFDTQLAEYQKVI 1414
Cdd:COG4913   743 arLELRALLEERFAAALGDAVE--RELRENLEERIDALRARLNRAEEELERAMRAFNREWPAE--TADLDADLESLPEYL 818

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|
gi 442628159 1415 DEMDDAASV---------KSALLEQLQNRVAELETALRQA 1445
Cdd:COG4913   819 ALLDRLEEDglpeyeerfKELLNENSIEFVADLLSKLRRA 858
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 306-478 2.04e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 2.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  306 LREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQfcgDELNAQSQVYKE 385
Cdd:COG4942    32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR---AELEAQKEELAE 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  386 KIHDLEskitkLVSATPSLQSILPPDLPSDDG---------------------ALQEEIAKLQEKMTIQQKEVESRIAEQ 444
Cdd:COG4942   109 LLRALY-----RLGRQPPLALLLSPEDFLDAVrrlqylkylaparreqaeelrADLAELAALRAELEAERAELEALLAEL 183

                         170       180       190
                  ....*....|....*....|....*....|....
gi 442628159  445 LEEEQRLRENVKYLNEQIATLQSELVSKDEALEK 478
Cdd:COG4942   184 EEERAALEALKAERQKLLARLEKELAELAAELAE 217
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1159-1383 2.35e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.59  E-value: 2.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1159 LQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQ 1238
Cdd:COG3883    18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1239 vQEANGDIKDSLVKVEEL------VKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQA 1312
Cdd:COG3883    98 -SGGSVSYLDVLLGSESFsdfldrLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 442628159 1313 NGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQAN 1383
Cdd:COG3883   177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAA 247
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 628-905 2.47e-04

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 46.19  E-value: 2.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  628 EQLEKQisdLKQLAEQEKLVREMTENAINQIQLEKESIEQQLalKQNELEDF----QKKQSESEVHLQEIKAQNTQKDFE 703
Cdd:PTZ00108 1002 GKLERE---LARLSNKVRFIKHVINGELVITNAKKKDLVKEL--KKLGYVRFkdiiKKKSEKITAEEEEGAEEDDEADDE 1076

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  704 LVESG--------------------ESLKKLQQQLEQKTLGHEKLQAA------LEELKKEKETIIKEKEQE----LQQL 753
Cdd:PTZ00108 1077 DDEEElgaavsydyllsmpiwsltkEKVEKLNAELEKKEKELEKLKNTtpkdmwLEDLDKFEEALEEQEEVEekeiAKEQ 1156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  754 QSKSAESESALKVVQ-VQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLE 832
Cdd:PTZ00108 1157 RLKSKTKGKASKLRKpKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPK 1236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442628159  833 EEAKKSGHLLEQITKLKSEVGETQaalSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEIT 905
Cdd:PTZ00108 1237 KSSVKRLKSKKNNSSKSSEDNDEF---SSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPT 1306
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
306-750 2.56e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 2.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  306 LREKQQHVEKLMVERDlDREDAQNQALQLQKNINELKARIVELESALDNER--KKTEELQCSIDEAQFCGDELNAQSQVY 383
Cdd:COG4717    80 LKEAEEKEEEYAELQE-ELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPERLEELEERLEEL 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  384 KEKIHDLESKITKLVSATPSLQSILPPDLPSDDGALQEEIAKLQekmtiqqkEVESRIAEQLEEEQRLRENVKYLNEQIA 463
Cdd:COG4717   159 RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE--------ELQQRLAELEEELEEAQEELEELEEELE 230

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  464 TLQSELVSKDEALEKFSLSE--------CGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKAT 535
Cdd:COG4717   231 QLENELEAAALEERLKEARLllliaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQAL 310

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  536 SDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEvttqlnVQKADSSALDDMLRLQKEGTE-EKSTLLEKTEKELV 614
Cdd:COG4717   311 PALEELEEEELEELLAALGLPPDLSPEELLELLDRIEE------LQELLREAEELEEELQLEELEqEIAALLAEAGVEDE 384

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  615 QSKEQAAKTLNDKEQLEKQISDLK-QLAEQEKLVREMTENAI-NQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQE 692
Cdd:COG4717   385 EELRAALEQAEEYQELKEELEELEeQLEELLGELEELLEALDeEELEEELEELEEELEELEEELEELREELAELEAELEQ 464

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 442628159  693 IKAQNtqkdfELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQEL 750
Cdd:COG4717   465 LEEDG-----ELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPPV 517
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1097-1236 2.94e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.15  E-value: 2.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1097 ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQ---ESQTSKEkLTEIQQSLQELQDSVKQKEELV 1173
Cdd:COG1579    34 AELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEqlgNVRNNKE-YEALQKEIESLKRRISDLEDEI 112

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442628159 1174 QNLEEKVRESSSIIEAQNTKLNESNVQLENKTsclKETQDQLLESQKKEKQLQEEAAKLSGEL 1236
Cdd:COG1579   113 LELMERIEELEEELAELEAELAELEAELEEKK---AELDEELAELEAELEELEAEREELAAKI 172
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
615-818 3.32e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.39  E-value: 3.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  615 QSKEQAAKTLndkEQLEKQISDLK-QLAEQEKLVRE-MTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQE 692
Cdd:COG3206   168 LRREEARKAL---EFLEEQLPELRkELEEAEAALEEfRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAA 244

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  693 IKAQNTQKDFELVESGES---------LKKLQQQLEQKTL----GHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAE 759
Cdd:COG3206   245 LRAQLGSGPDALPELLQSpviqqlraqLAELEAELAELSArytpNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEA 324

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 442628159  760 SESALKVVQVQLEQLQQQaaasgeegSKTVAKLHDEISQLKSQAEETQSELKSTQSNLE 818
Cdd:COG3206   325 LQAREASLQAQLAQLEAR--------LAELPELEAELRRLEREVEVARELYESLLQRLE 375
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 727-894 3.40e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.15  E-value: 3.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  727 KLQAALEELKKEKETI---IKEKEQELQQLQSKSAESESALKVVQvqleqlqqqaaasgeegsKTVAKLHDEISQLKSQA 803
Cdd:COG1579    14 ELDSELDRLEHRLKELpaeLAELEDELAALEARLEAAKTELEDLE------------------KEIKRLELEIEEVEARI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  804 EETQSELKSTQSN--LEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALE 881
Cdd:COG1579    76 KKYEEQLGNVRNNkeYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELE 155

                         170
                  ....*....|...
gi 442628159  882 KVNKEYAESRAEA 894
Cdd:COG1579   156 AELEELEAEREEL 168
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 312-1045 3.51e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 45.60  E-value: 3.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   312 HVEKL---MVERDLDREDAQNQalqlqknineLKARIVELESALDNERKKTEELQCSIDEAQfcgdeLNAQSQVYKEKIH 388
Cdd:pfam12128  180 HIDKIakaMHSKEGKFRDVKSM----------IVAILEDDGVVPPKSRLNRQQVEHWIRDIQ-----AIAGIMKIRPEFT 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   389 DLESKITKLVSATPSLQSilppdlpsddgaLQEEIAKLQEKMTIQQKEVESRIAEQleeEQRLRENVKYLNEQIATLQSE 468
Cdd:pfam12128  245 KLQQEFNTLESAELRLSH------------LHFGYKSDETLIASRQEERQETSAEL---NQLLRTLDDQWKEKRDELNGE 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   469 LVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERV--NK 546
Cdd:pfam12128  310 LSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKeqNN 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   547 TDECEILQTEVRMRDEQIRelnqqldevttQLNVQKADSSALDDMLRLQKEGT----EEKSTLLEKTEKELVQSKEQAAK 622
Cdd:pfam12128  390 RDIAGIKDKLAKIREARDR-----------QLAVAEDDLQALESELREQLEAGklefNEEEYRLKSRLGELKLRLNQATA 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   623 TLNDKEQLEKQISDLKQLAE-QEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKD 701
Cdd:pfam12128  459 TPELLLQLENFDERIERAREeQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLH 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   702 FELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQsksaesesalkvvqvqleqlqqqaaas 781
Cdd:pfam12128  539 FLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRID--------------------------- 591

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   782 geegsktVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKsghlLEQITKLKSEVGETQAALSS 861
Cdd:pfam12128  592 -------VPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASRE----ETFARTALKNARLDLRRLFD 660

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   862 CHTDVESK-TKQLEAANA-ALEKVNKEYAESRAEASDLQDKVKEITDTL----HAELQAERSSSSALHTKLSKFSDEIA- 934
Cdd:pfam12128  661 EKQSEKDKkNKALAERKDsANERLNSLEAQLKQLDKKHQAWLEEQKEQKrearTEKQAYWQVVEGALDAQLALLKAAIAa 740

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   935 --TGHKELTSKADAWSQEMLQK-----------EKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAK 1001
Cdd:pfam12128  741 rrSGAKAELKALETWYKRDLASlgvdpdviaklKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIE 820

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 442628159  1002 TENLELstgtQTTIKDLQERLEITNAELQhKEKMASEDAQKIAD 1045
Cdd:pfam12128  821 RAISEL----QQQLARLIADTKLRRAKLE-MERKASEKQQVRLS 859
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
438-682 4.03e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 4.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  438 ESRIAEQLEEEQRLRENVKYLNEQIATLQSELvskdEALEKFSLSECGIENLRRELELLKeenekQAQEAQAEFTRKLAE 517
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAEL----DALQERREALQRLAEYSWDEIDVA-----SAEREIAELEAELER 679

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  518 ksveVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNvqkadssalddmlRLQKE 597
Cdd:COG4913   680 ----LDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE-------------AAEDL 742

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  598 GTEEKSTLLEKTEKELVQSKEQAAKtlndKEQLEKQISDLKQLAEQ--EKLVREMTE------NAINQIQLEKESIEQQL 669
Cdd:COG4913   743 ARLELRALLEERFAAALGDAVEREL----RENLEERIDALRARLNRaeEELERAMRAfnrewpAETADLDADLESLPEYL 818

                         250
                  ....*....|....*..
gi 442628159  670 A----LKQNELEDFQKK 682
Cdd:COG4913   819 AlldrLEEDGLPEYEER 835
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 680-921 4.56e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 4.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  680 QKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQktlgHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAE 759
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAA----LERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  760 SESALKVVQVQLEQLQQQAAASGEegsktvaklHDEISQLKSQAEETQSE--LKSTQSNLEAKSKQLEAANGSLEEEAKK 837
Cdd:COG4942    95 LRAELEAQKEELAELLRALYRLGR---------QPPLALLLSPEDFLDAVrrLQYLKYLAPARREQAEELRADLAELAAL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  838 SGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERS 917
Cdd:COG4942   166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245


                  ....
gi 442628159  918 SSSA 921
Cdd:COG4942   246 AGFA 249
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1301-1506 4.98e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 4.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1301 AVTEKLQQLEQANGELKEALCQKengLKELQGKLDEsntvLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLK 1380
Cdd:COG4717    50 RLEKEADELFKPQGRKPELNLKE---LKELEEELKE----AEEKEEEYAELQEELEELEEELEELEAELEELREELEKLE 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1381 QANE------ELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYL 1454
Cdd:COG4717   123 KLLQllplyqELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE 202

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 442628159 1455 ETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKI 1506
Cdd:COG4717   203 ELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLI 254
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1028-1475 5.17e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 44.81  E-value: 5.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1028 ELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEK--SETNHIFELFEMEADMN-SERLIEKVT 1104
Cdd:pfam10174  213 EELHRRNQLQPDPAKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGllHTEDREEEIKQMEVYKShSKFMKNKID 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1105 GIKEEL--KETHL------------QLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKE 1170
Cdd:pfam10174  293 QLKQELskKESELlalqtkletltnQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLT 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1171 ELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDI---- 1246
Cdd:pfam10174  373 EEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKerii 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1247 --------KDSLVKVEELvKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKE 1318
Cdd:pfam10174  453 erlkeqreREDRERLEEL-ESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKE 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1319 ALCQKENGLKELQGkldesntvLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQlllE 1398
Cdd:pfam10174  532 ECSKLENQLKKAHN--------AEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKD---K 600

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 442628159  1399 KGNEFDTQLAEYQKviDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAyletkeLRRQLESL--ELEKSREVL 1475
Cdd:pfam10174  601 KIAELESLTLRQMK--EQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNS------QQLQLEELmgALEKTRQEL 671
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1097-1418 5.21e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.12  E-value: 5.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1097 ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNL 1176
Cdd:COG4372    48 EQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDL 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1177 EEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEEL 1256
Cdd:COG4372   128 EQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEK 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1257 VKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDE 1336
Cdd:COG4372   208 LIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEA 287

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1337 SNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE 1416
Cdd:COG4372   288 LEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLSKGAEAGV 367


                  ..
gi 442628159 1417 MD 1418
Cdd:COG4372   368 AD 369
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
587-763 5.28e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 5.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  587 ALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQL-----E 661
Cdd:COG4717    54 EADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLlplyqE 133

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  662 KESIEQQLALKQNELEDFQKKQ---SESEVHLQEIKAQNTQKDFELVESGESLK-KLQQQLEQKTLGHEKLQAALEELKK 737
Cdd:COG4717   134 LEALEAELAELPERLEELEERLeelRELEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQRLAELEE 213

                         170       180
                  ....*....|....*....|....*.
gi 442628159  738 EKETIIKEKEQELQQLQSKSAESESA 763
Cdd:COG4717   214 ELEEAQEELEELEEELEQLENELEAA 239
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 690-921 5.30e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.44  E-value: 5.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  690 LQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEketiIKEKEQELQQLQSKSAESESALKVVQV 769
Cdd:COG3883    18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAE----IDKLQAEIAEAEAEIEERREELGERAR 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  770 QLEQLQQQAAASGE-EGSKTVAKLHDEISQLKSQAEETQS---ELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQI 845
Cdd:COG3883    94 ALYRSGGSVSYLDVlLGSESFSDFLDRLSALSKIADADADlleELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 442628159  846 TKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSA 921
Cdd:COG3883   174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGA 249
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
1149-1409 6.04e-04

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 44.30  E-value: 6.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1149 KEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSsIIEAQNTKLNESNvqlenktscLKETQDQLLESqkkEKQLQEE 1228
Cdd:COG0497   154 EELLEEYREAYRAWRALKKELEELRADEAERARELD-LLRFQLEELEAAA---------LQPGEEEELEE---ERRRLSN 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1229 AAKLSGELQQVQEAngdIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVT---EK 1305
Cdd:COG0497   221 AEKLREALQEALEA---LSGGEGGALDLLGQALRALERLAEYDPSLAELAERLESALIELEEAASELRRYLDSLEfdpER 297

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1306 LQQLEQANGELKeALCQKENG--------LKELQGKLDEsntvLESqkkshneIQDKLEQAQQKERTLQEETSKLAEQLS 1377
Cdd:COG0497   298 LEEVEERLALLR-RLARKYGVtveellayAEELRAELAE----LEN-------SDERLEELEAELAEAEAELLEAAEKLS 365

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 442628159 1378 QL-KQANEELQKSLQQ--KQLLLEKGnEFDTQLAE 1409
Cdd:COG0497   366 AArKKAAKKLEKAVTAelADLGMPNA-RFEVEVTP 399
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 302-960 6.12e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.65  E-value: 6.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   302 MQDLLREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVE---LESALDNERKKTEELQCSidEAQFCGDELNA 378
Cdd:TIGR00606  417 LQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKElqqLEGSSDRILELDQELRKA--ERELSKAEKNS 494

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   379 QSQVYKEKIHDLESKitklvsatpslqsilPPDLPSDDGALQEEIAKLQEKMTiQQKEVESRIAEQLEEEQRLRENVKYL 458
Cdd:TIGR00606  495 LTETLKKEVKSLQNE---------------KADLDRKLRKLDQEMEQLNHHTT-TRTQMEMLTKDKMDKDEQIRKIKSRH 558

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   459 NEQIATLQSELVSKDEaLEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSEL------QNL 532
Cdd:TIGR00606  559 SDELTSLLGYFPNKKQ-LEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsQDE 637

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   533 KATSDSLESERVNKTDECEILQTEVRMRDEQIREL---NQQLDEVTTQLNVQKAD----SSALDDMLRLQKEGTEEKSTL 605
Cdd:TIGR00606  638 ESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLtdeNQSCCPVCQRVFQTEAElqefISDLQSKLRLAPDKLKSTESE 717

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   606 LEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQlaEQEKLVREMTE--NAINQIQLEKESIEQQLALKQNELED----- 678
Cdd:TIGR00606  718 LKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRN--KLQKVNRDIQRlkNDIEEQETLLGTIMPEEESAKVCLTDvtime 795

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   679 -FQKKQSESEVHLQEIKAQNTQKDFELvesgeSLKKLQQQLEQKTLGHEKLQAALEELKKeketIIKEKEQELQQLQSKS 757
Cdd:TIGR00606  796 rFQMELKDVERKIAQQAAKLQGSDLDR-----TVQQVNQEKQEKQHELDTVVSKIELNRK----LIQDQQEQIQHLKSKT 866

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   758 AESESAlKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKK 837
Cdd:TIGR00606  867 NELKSE-KLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVND 945

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   838 SGHLLEQITKLKSEV------------GETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQD------ 899
Cdd:TIGR00606  946 IKEKVKNIHGYMKDIenkiqdgkddylKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDnltlrk 1025

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442628159   900 ---KVKEITDTLHAEL----QAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQE 960
Cdd:TIGR00606 1026 renELKEVEEELKQHLkemgQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELRE 1093
COG5022 COG5022
Myosin heavy chain [General function prediction only];
512-832 7.36e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 44.30  E-value: 7.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  512 TRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEIL---QTEVRMRDEQIRELNQQLDEVTTQLNVQKAD---- 584
Cdd:COG5022   829 EKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYlqsAQRVELAERQLQELKIDVKSISSLKLVNLELesei 908

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  585 ---SSALDDMLRLQKEGTEEKSTLLEKTEKElVQSKEQAAKTLNDKEQLEK---QISDLKQLAEQEKLVREMTENAINQI 658
Cdd:COG5022   909 ielKKSLSSDLIENLEFKTELIARLKKLLNN-IDLEEGPSIEYVKLPELNKlheVESKLKETSEEYEDLLKKSTILVREG 987

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  659 QLEKESIE---QQLALKQNELEDFQKKQSESEVHLQEI--KAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALE 733
Cdd:COG5022   988 NKANSELKnfkKELAELSKQYGALQESTKQLKELPVEVaeLQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYK 1067

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  734 ELKKEKETIIKEKEQELQQLQSKSAESESALKvvqvqleqlqqQAAASGEEGSKTVAKLHDEISQLKSQAEETQSE--LK 811
Cdd:COG5022  1068 ALKLRRENSLLDDKQLYQLESTENLLKTINVK-----------DLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISkfLS 1136

                         330       340
                  ....*....|....*....|.
gi 442628159  812 STQSNLEAKSKQLEAANGSLE 832
Cdd:COG5022  1137 QLVNTLEPVFQKLSVLQLELD 1157
mukB PRK04863
chromosome partition protein MukB;
1016-1387 7.56e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.56  E-value: 7.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1016 KDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANisatnaeLSTVLEVLQAEKSETNHIFELFEM----- 1090
Cdd:PRK04863  293 RELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDH-------LNLVQTALRQQEKIERYQADLEELeerle 365

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1091 -------EADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQ-ESQTSKEKLTE--IQQSLQ 1160
Cdd:PRK04863  366 eqnevveEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALERaKQLCGLPDLTAdnAEDWLE 445

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1161 ELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLN---------ESNVQLENKTSCLKETQDQLLESQKKEkQLQEEAAK 1231
Cdd:PRK04863  446 EFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQlvrkiagevSRSEAWDVARELLRRLREQRHLAEQLQ-QLRMRLSE 524

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1232 LSGELQQVQEANgDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQ 1311
Cdd:PRK04863  525 LEQRLRQQQRAE-RLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAP 603

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 442628159 1312 ANGELKEALCQkengLKELQGKLDESNTVLESQkkshneIQDKLEqaqqKERTLQEETSKLAEQLSQLKQANEELQ 1387
Cdd:PRK04863  604 AWLAAQDALAR----LREQSGEEFEDSQDVTEY------MQQLLE----RERELTVERDELAARKQALDEEIERLS 665
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
546-745 8.63e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 8.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  546 KTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKA---DSSALDDMLRLQKEgteekstlLEKTEKELvqskEQAAK 622
Cdd:COG4913   615 LEAELAELEEELAEAEERLEALEAELDALQERREALQRlaeYSWDEIDVASAERE--------IAELEAEL----ERLDA 682

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  623 TLNDKEQLEKQISDLKQLAEQeklvremTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDF 702
Cdd:COG4913   683 SSDDLAALEEQLEELEAELEE-------LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERF 755

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 442628159  703 ELVESGESLKKLQQQLEQKTlghEKLQAALEELKKEKETIIKE 745
Cdd:COG4913   756 AAALGDAVERELRENLEERI---DALRARLNRAEEELERAMRA 795
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1315-1504 9.23e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.67  E-value: 9.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1315 ELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEEtskLAEQLSQLKQANEELQKSLQQKQ 1394
Cdd:COG3883    20 AKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAE---IAEAEAEIEERREELGERARALY 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1395 -------------------------LLLEKGNEFDTQ-LAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDA 1448
Cdd:COG3883    97 rsggsvsyldvllgsesfsdfldrlSALSKIADADADlLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 442628159 1449 QKTAYLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLA 1504
Cdd:COG3883   177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAA 232
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1173-1480 1.10e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.79  E-value: 1.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1173 VQNLEEKVRESSSIIEAQNTKLNESNVQLENKTScLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEA---------- 1242
Cdd:COG3096   274 MRHANERRELSERALELRRELFGARRQLAEEQYR-LVEMARELEELSARESDLEQDYQAASDHLNLVQTAlrqqekiery 352

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1243 NGDIKDSLVKVEELVKVLE---EKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQAngelkEA 1319
Cdd:COG3096   353 QEDLEELTERLEEQEEVVEeaaEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKA-----RA 427

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1320 LCQK--------ENGLKELQGKLDE-SNTVLESQKK------SHNEIQDKLE------------QAQQKERTLQE---ET 1369
Cdd:COG3096   428 LCGLpdltpenaEDYLAAFRAKEQQaTEEVLELEQKlsvadaARRQFEKAYElvckiageversQAWQTARELLRryrSQ 507

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1370 SKLAEQLSQLKQANEELQKSLQQKQlllekgnEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQ 1449
Cdd:COG3096   508 QALAQRLQQLRAQLAELEQRLRQQQ-------NAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQR 580

                         330       340       350
                  ....*....|....*....|....*....|.
gi 442628159 1450 KTAYLETKELRRQLESLElekSREVLSLKAQ 1480
Cdd:COG3096   581 SELRQQLEQLRARIKELA---ARAPAWLAAQ 608
PRK01156 PRK01156
chromosome segregation protein; Provisional
 714-1318 1.12e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 43.74  E-value: 1.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  714 LQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAlkvvqvqleqlqqqaaasgEEGSKTVAKLH 793
Cdd:PRK01156  188 LEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNL-------------------KSALNELSSLE 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  794 DEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQL 873
Cdd:PRK01156  249 DMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAII 328

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  874 EAAnAALEKVNKEYAESRAEASDLQDKVKEItDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQ 953
Cdd:PRK01156  329 KKL-SVLQKDYNDYIKKKSRYDDLNNQILEL-EGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDA 406

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  954 KEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTT---IKDLQERLEITNAELQ 1030
Cdd:PRK01156  407 IKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVCGTTLGEEKSnhiINHYNEKKSRLEEKIR 486

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1031 HKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVlqaeksetnhifelfEMEADMNSErliekvtgikEEL 1110
Cdd:PRK01156  487 EIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIESARA---------------DLEDIKIKI----------NEL 541

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1111 KETHLQLDERQKKFEELEEKLKQAQQSEQkLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQ 1190
Cdd:PRK01156  542 KDKHDKYEEIKNRYKSLKLEDLDSKRTSW-LNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKS 620

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1191 NTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSlvkvEELVKVLEEKLQAATSQ 1270
Cdd:PRK01156  621 IREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDI----EDNLKKSRKALDDAKAN 696

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|..
gi 442628159 1271 LDAQQATNKEL----QELLVKSQENEGNLqgeslavtEKLQQLEQANGELKE 1318
Cdd:PRK01156  697 RARLESTIEILrtriNELSDRINDINETL--------ESMKKIKKAIGDLKR 740
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 663-1245 1.15e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 43.59  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   663 ESIEQQLALKQNELEDFQKKQSEsevhLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETI 742
Cdd:pfam07111   59 QALSQQAELISRQLQELRRLEEE----VRLLRETSLQQKMRLEAQAMELDALAVAEKAGQAEAEGLRAALAGAEMVRKNL 134

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   743 IKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTV----AKLHDEISQLKSQAEETQSELKSTQSNLE 818
Cdd:pfam07111  135 EEGSQRELEEIQRLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLNSLetkrAGEAKQLAEAQKEAELLRKQLSKTQEELE 214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   819 AKSKQLEAANGSLEEEAKKSGH----------LLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEK------ 882
Cdd:pfam07111  215 AQVTLVESLRKYVGEQVPPEVHsqtwelerqeLLDTMQHLQEDRADLQATVELLQVRVQSLTHMLALQEEELTRkiqpsd 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   883 -VNKEYAES-RAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSkfsdeiatghkELTSKADAWSQEMLQKEKELQE 960
Cdd:pfam07111  295 sLEPEFPKKcRSLLNRWREKVFALMVQLKAQDLEHRDSVKQLRGQVA-----------ELQEQVTSQSQEQAILQRALQD 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   961 LRQQLQDSQDSQTKLKAEGERKEKSfeesiKNLQEEVTKAKTENLELSTG----TQTTIKDLQERLEITNAELQHKEKMA 1036
Cdd:pfam07111  364 KAAEVEVERMSAKGLQMELSRAQEA-----RRRQQQQTASAEEQLKFVVNamssTQIWLETTMTRVEQAVARIPSLSNRL 438

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1037 SEDAQKIADLKTLVeAIQVANANISA-----------TNAELSTVLEVLQAEKSETNHIFELfemeadmnSERLIEKVTG 1105
Cdd:pfam07111  439 SYAVRKVHTIKGLM-ARKVALAQLRQescpppppappVDADLSLELEQLREERNRLDAELQL--------SAHLIQQEVG 509

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1106 IKEELKEThlqlderqkkfeELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDS-----------VKQKEELVQ 1174
Cdd:pfam07111  510 RAREQGEA------------ERQQLSEVAQQLEQELQRAQESLASVGQQLEVARQGQQESteeaaslrqelTQQQEIYGQ 577

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1175 NLEEKVRESSSIIEAQ--NTKLNESNVQLENKTSCLKETQDQLLESQKKE-----KQLQEEAAKLSGE--LQQVQEANGD 1245
Cdd:pfam07111  578 ALQEKVAEVETRLREQlsDTKRRLNEARREQAKAVVSLRQIQHRATQEKErnqelRRLQDEARKEEGQrlARRVQELERD 657
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1362-1531 1.20e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1362 ERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLL---EKGNEFDTQLAEYQkVIDEMDDAASV--KSALLEQLQNRVA 1436
Cdd:COG4913   220 EPDTFEAADALVEHFDDLERAHEALEDAREQIELLEpirELAERYAAARERLA-ELEYLRAALRLwfAQRRLELLEAELE 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1437 ELETALRQANDAQKtayletkELRRQLESLEleksREVLSLKAQMNGASsrsgkGDEVESLDietslAKINFLNSIIADM 1516
Cdd:COG4913   299 ELRAELARLEAELE-------RLEARLDALR----EELDELEAQIRGNG-----GDRLEQLE-----REIERLERELEER 357

                         170
                  ....*....|....*
gi 442628159 1517 QQKNDALKAKVQTLE 1531
Cdd:COG4913   358 ERRRARLEALLAALG 372
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 791-1485 1.33e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 43.64  E-value: 1.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  791 KLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAkksgHLLEQITKLKSEVGETQAALSSCHTDVESKT 870
Cdd:PRK10246  202 KLQAQASGVALLTPEQVQSLTASLQVLTDEEKQLLTAQQQQQQSL----NWLTRLDELQQEASRRQQALQQALAAEEKAQ 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  871 KQLEAAN-------------------AALEKVNKEYAESRA---EASDLQDKVKEITDTLHAELQAERSSSS---ALHTK 925
Cdd:PRK10246  278 PQLAALSlaqparqlrphweriqeqsAALAHTRQQIEEVNTrlqSTMALRARIRHHAAKQSAELQAQQQSLNtwlAEHDR 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  926 LSKFSDEIATGHKELT------SKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTK 999
Cdd:PRK10246  358 FRQWNNELAGWRAQFSqqtsdrEQLRQWQQQLTHAEQKLNALPAITLTLTADEVAAALAQHAEQRPLRQRLVALHGQIVP 437

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1000 AKTENLELstgtQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAiqvananiSATNAELSTVLEVLQAEK- 1078
Cdd:PRK10246  438 QQKRLAQL----QVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQ--------EARIKDLEAQRAQLQAGQp 505

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1079 ----SETNH--IFELFEMEADMNSERL--IEK-VTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSK 1149
Cdd:PRK10246  506 cplcGSTSHpaVEAYQALEPGVNQSRLdaLEKeVKKLGEEGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAVC 585

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1150 EKLTEIQQSLQELQDSVKQKEELVQNLEE--KVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQL---LESQKKEKQ 1224
Cdd:PRK10246  586 ASLNITLQPQDDIQPWLDAQEEHERQLRLlsQRHELQGQIAAHNQQIIQYQQQIEQRQQQLLTALAGYaltLPQEDEEAS 665

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1225 LQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQgeslavte 1304
Cdd:PRK10246  666 WLATRQQEAQSWQQRQNELTALQNRIQQLTPLLETLPQSDDLPHSEETVALDNWRQVHEQCLSLHSQLQTLQ-------- 737

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1305 klQQLEQANGELKEALCQKENGLKelqgkldesNTVLESqkkshneiqdkleQAQQKERTLQEETsklAEQLSQLKQAne 1384
Cdd:PRK10246  738 --QQDVLEAQRLQKAQAQFDTALQ---------ASVFDD-------------QQAFLAALLDEET---LTQLEQLKQN-- 788

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1385 eLQKSLQQKQLLLEKGNEfdtQLAEYQKVIDE-MDDAASVksallEQLQNRVAELETALRQANDAQktayletKELRRQL 1463
Cdd:PRK10246  789 -LENQRQQAQTLVTQTAQ---ALAQHQQHRPDgLDLTVTV-----EQIQQELAQLAQQLRENTTRQ-------GEIRQQL 852

                         730       740
                  ....*....|....*....|..
gi 442628159 1464 ESlELEKSREVLSLKAQMNGAS 1485
Cdd:PRK10246  853 KQ-DADNRQQQQALMQQIAQAT 873
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 333-707 1.33e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 43.50  E-value: 1.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  333 QLQKNINELKARIVE-LESALD--NERKKTEElqcSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLvsatpslqsilP 409
Cdd:PRK10929   34 QAKAAKTPAQAEIVEaLQSALNwlEERKGSLE---RAKQYQQVIDNFPKLSAELRQQLNNERDEPRSV-----------P 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  410 PDLPSDDgaLQEEIAKLQEKMTIQqkevesriAEQLEEEQ-RLRENVKYLNeQIATLQSELvskdealeKFSLSEcgIEN 488
Cdd:PRK10929  100 PNMSTDA--LEQEILQVSSQLLEK--------SRQAQQEQdRAREISDSLS-QLPQQQTEA--------RRQLNE--IER 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  489 LRRELELLKeenekqAQEAQAEFTRKLAEKSVevlrlsselqnLKATSDSLESERVNKTDECEIlqteVRMRDE----QI 564
Cdd:PRK10929  159 RLQTLGTPN------TPLAQAQLTALQAESAA-----------LKALVDELELAQLSANNRQEL----ARLRSElakkRS 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  565 RELNQQLDEVTTQLNV--QKADSSALDDMLRLQKEGTEEKSTLLE--KTEKELVQSKEQAAKTLND-------------- 626
Cdd:PRK10929  218 QQLDAYLQALRNQLNSqrQREAERALESTELLAEQSGDLPKSIVAqfKINRELSQALNQQAQRMDLiasqqrqaasqtlq 297

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  627 --------KEQ-------------LEKQISDLKQLAEQEKLVREMTENAINQIQLEkESIEQQLALKQNELEDFQKKQSE 685
Cdd:PRK10929  298 vrqalntlREQsqwlgvsnalgeaLRAQVARLPEMPKPQQLDTEMAQLRVQRLRYE-DLLNKQPQLRQIRQADGQPLTAE 376

                         410       420
                  ....*....|....*....|...
gi 442628159  686 SEVHLQE-IKAQNtqkdfELVES 707
Cdd:PRK10929  377 QNRILDAqLRTQR-----ELLNS 394
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 1011-1396 1.36e-03

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 43.29  E-value: 1.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1011 TQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQvanANISATNAELSTVLEVLQAEKSETNHIFELFE- 1089
Cdd:PRK04778  110 IESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYRELR---KSLLANRFSFGPALDELEKQLENLEEEFSQFVe 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1090 -------MEADMNSERLIEKVTGIKEELKETHLQLDERQKKF----EELEEKLKQAQQS-----EQKLQQESQTSKEKLT 1153
Cdd:PRK04778  187 ltesgdyVEAREILDQLEEELAALEQIMEEIPELLKELQTELpdqlQELKAGYRELVEEgyhldHLDIEKEIQDLKEQID 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1154 EIQQSLQELQdsVKQKEELVQNLEEKVRESSSIIEaqnTKLNESNVQLENKtsclKETQDQLLESQKKEKQLQEEAAKLS 1233
Cdd:PRK04778  267 ENLALLEELD--LDEAEEKNEEIQERIDQLYDILE---REVKARKYVEKNS----DTLPDFLEHAKEQNKELKEEIDRVK 337

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1234 -------GELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATS---QLDAQQATNKELQELLVKSQENEGNLQGESLAVT 1303
Cdd:PRK04778  338 qsytlneSELESVRQLEKQLESLEKQYDEITERIAEQEIAYSElqeELEEILKQLEEIEKEQEKLSEMLQGLRKDELEAR 417

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1304 EKLQQLEQANGELKEALcQKEN--GL--------KELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSK-- 1371
Cdd:PRK04778  418 EKLERYRNKLHEIKRYL-EKSNlpGLpedylemfFEVSDEIEALAEELEEKPINMEAVNRLLEEATEDVETLEEETEElv 496

                         410       420       430
                  ....*....|....*....|....*....|...
gi 442628159 1372 ----LAEQLSQ----LKQANEELQKSLQQKQLL 1396
Cdd:PRK04778  497 enatLTEQLIQyanrYRSDNEEVAEALNEAERL 529
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 346-1369 1.39e-03

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 43.67  E-value: 1.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  346 VELESALDNERKKTEELQCSIDEAQFCGDELNAQSQ---VYKEKIHDLESKITKLVSATP-SLQSILppDLPSDDGALQ- 420
Cdd:PTZ00440  487 EKKESSDSNYQEKVDELLQIINSIKEKNNIVNNNFKnieDYYITIEGLKNEIEGLIELIKyYLQSIE--TLIKDEKLKRs 564

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  421 -------------------EEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSL 481
Cdd:PTZ00440  565 mkndiknkikyieenvdhiKDIISLNDEIDNIIQQIEELINEALFNKEKFINEKNDLQEKVKYILNKFYKGDLQELLDEL 644

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  482 SECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVL-----RLSSELQNLKATSDSLESERVNKtdeceiLQTE 556
Cdd:PTZ00440  645 SHFLDDHKYLYHEAKSKEDLQTLLNTSKNEYEKLEFMKSDNIdniikNLKKELQNLLSLKENIIKKQLNN------IEQD 718

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  557 VRMRDEQIRElnqQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQL---EKQ 633
Cdd:PTZ00440  719 ISNSLNQYTI---KYNDLKSSIEEYKEEEEKLEVYKHQIINRKNEFILHLYENDKDLPDGKNTYEEFLQYKDTIlnkENK 795

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  634 IS-DLKQLAEQEKLVREMTENAINQIQLEK-------ESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELV 705
Cdd:PTZ00440  796 ISnDINILKENKKNNQDLLNSYNILIQKLEahtekndEELKQLLQKFPTEDENLNLKELEKEFNENNQIVDNIIKDIENM 875

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  706 ESG-ESLKKLQQQLEqktlGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAlkvvqvqleqLQQQAAASGEE 784
Cdd:PTZ00440  876 NKNiNIIKTLNIAIN----RSNSNKQLVEHLLNNKIDLKNKLEQHMKIINTDNIIQKNE----------KLNLLNNLNKE 941

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  785 GSKTVAKLHDE-ISQLKSQAEETQSELKSTQSNLEAKSK-QLEaangSLEEEAKKSGHLLEQITKLKSEVGETQAALSSc 862
Cdd:PTZ00440  942 KEKIEKQLSDTkINNLKMQIEKTLEYYDKSKENINGNDGtHLE----KLDKEKDEWEHFKSEIDKLNVNYNILNKKIDD- 1016

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  863 hTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTS 942
Cdd:PTZ00440 1017 -LIKKQHDDIIELIDKLIKEKGKEIEEKVDQYISLLEKMKTKLSSFHFNIDIKKYKNPKIKEEIKLLEEKVEALLKKIDE 1095

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  943 KADAWSQEMLQKEKELQELRQQLQdsqdsqtKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTqttikdlqerl 1022
Cdd:PTZ00440 1096 NKNKLIEIKNKSHEHVVNADKEKN-------KQTEHYNKKKKSLEKIYKQMEKTLKELENMNLEDITLN----------- 1157

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1023 EITNAELQHKEKMASEDAQKIAD-----------LKTLVEAIQVANANISATNAELSTVLEVLQAEKSETnhifelfemE 1091
Cdd:PTZ00440 1158 EVNEIEIEYERILIDHIVEQINNeakksktimeeIESYKKDIDQVKKNMSKERNDHLTTFEYNAYYDKAT---------A 1228

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1092 ADMNSERLIEKVTGIKEElkethlqlDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQ------------QSL 1159
Cdd:PTZ00440 1229 SYENIEELTTEAKGLKGE--------ANRSTNVDELKEIKLQVFSYLQQVIKENNKMENALHEIKnmyeflisidseKIL 1300

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1160 QELQDSVKQKEELVQNLEEKVRESSSIIEaqntklnesnvQLENKTSCLKETQDQLLESQkKEKQLQEEAAKLSGELQQV 1239
Cdd:PTZ00440 1301 KEILNSTKKAEEFSNDAKKELEKTDNLIK-----------QVEAKIEQAKEHKNKIYGSL-EDKQIDDEIKKIEQIKEEI 1368

                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1240 QEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEklQQLEQANGELKEA 1319
Cdd:PTZ00440 1369 SNKRKEINKYLSNIKSNKEKCDLHVRNASRGKDKIDFLNKHEAIEPSNSKEVNIIKITDNINKCK--QYSNEAMETENKA 1446

                        1050      1060      1070      1080      1090      1100
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 442628159 1320 LCQKENGLK-------------------ELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEET 1369
Cdd:PTZ00440 1447 DENNDSIIKyekeitnilnnssilgkktKLEKKKKEATNIMDDINGEHSIIKTKLTKSSEKLNQLNEQP 1515
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 292-685 1.43e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 42.96  E-value: 1.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   292 ILATPKSQFsMQDLLREKQQHVEKLMVE-------RDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQC 364
Cdd:pfam07888   23 LLVVPRAEL-LQNRLEECLQERAELLQAqeaanrqREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEE 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   365 SIDEAQFCGDELNAQSQVYKEKIHDLESKITKlvsatpslqsilppdlpsddgaLQEEIAKLQEKMTIQQKEVEsRIAEQ 444
Cdd:pfam07888  102 KYKELSASSEELSEEKDALLAQRAAHEARIRE----------------------LEEDIKTLTQRVLERETELE-RMKER 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   445 LEEEQRLRENVKYLNEQiatLQSELVSKDEALEKFSLSECGIENlrreLELLKEENEKQAQEAQAEFTRKLAEKSVEVLR 524
Cdd:pfam07888  159 AKKAGAQRKEEEAERKQ---LQAKLQQTEEELRSLSKEFQELRN----SLAQRDTQVLQLQDTITTLTQKLTTAHRKEAE 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   525 LSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVtTQLNVQKADSSAldDMLRLQKEGTEEKST 604
Cdd:pfam07888  232 NEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQARLQA-AQLTLQLADASL--ALREGRARWAQERET 308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   605 LLEKTEKELVQSKEQAAKTLNDKEQLEKQISDlKQLAEQEkLVREMTENAINQIQLEKESIEQQLALK--QNELEDFQKK 682
Cdd:pfam07888  309 LQQSAEADKDRIEKLSAELQRLEERLQEERME-REKLEVE-LGREKDCNRVQLSESRRELQELKASLRvaQKEKEQLQAE 386


                   ...
gi 442628159   683 QSE 685
Cdd:pfam07888  387 KQE 389
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 604-839 1.45e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.89  E-value: 1.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  604 TLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDF---Q 680
Cdd:COG3883    16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERaraL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  681 KKQSESEVHLQEIKAQNTQKDFelVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAES 760
Cdd:COG3883    96 YRSGGSVSYLDVLLGSESFSDF--LDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 442628159  761 ESALKVVQVQLEQLqqqaaasgeegSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSG 839
Cdd:COG3883   174 EAQQAEQEALLAQL-----------SAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 241
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
512-761 1.48e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 1.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  512 TRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQT---------EVRMRDEQIRELNQQLDEVTtqlnvqk 582
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRlaeyswdeiDVASAEREIAELEAELERLD------- 681

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  583 ADSSALDdmlRLQKEgteekstlLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQI---- 658
Cdd:COG4913   682 ASSDDLA---ALEEQ--------LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLElral 750

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  659 ------QLEKESIEQQLALK-QNELEDFQKKQSESEVHLQEIKAQ-NTQKDFELVESGESLKKLQQQLEQktlgHEKLQA 730
Cdd:COG4913   751 leerfaAALGDAVERELRENlEERIDALRARLNRAEEELERAMRAfNREWPAETADLDADLESLPEYLAL----LDRLEE 826

                         250       260       270
                  ....*....|....*....|....*....|...
gi 442628159  731 -ALEELKKE-KETIIKEKEQELQQLQSKSAESE 761
Cdd:COG4913   827 dGLPEYEERfKELLNENSIEFVADLLSKLRRAI 859
46 PHA02562
endonuclease subunit; Provisional
 1149-1396 1.48e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 43.08  E-value: 1.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1149 KEKLTEIQQSLQEL---QDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQL-ENKTSCLKETQDQLLEsqkkekq 1224
Cdd:PHA02562  173 KDKIRELNQQIQTLdmkIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEaKTIKAEIEELTDELLN------- 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1225 LQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEE--KLQAATSQLDaqqatnkELQELLVKSQENEGNLQGESLAV 1302
Cdd:PHA02562  246 LVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKggVCPTCTQQIS-------EGPDRITKIKDKLKELQHSLEKL 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1303 TEKLQQLEQANGELKEAlcqkENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQA 1382
Cdd:PHA02562  319 DTAIDELEEIMDEFNEQ----SKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKT 394

                         250
                  ....*....|....
gi 442628159 1383 NEELQKSLQQKQLL 1396
Cdd:PHA02562  395 KSELVKEKYHRGIV 408
PRK11637 PRK11637
AmiB activator; Provisional
 1148-1384 1.53e-03

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 42.76  E-value: 1.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1148 SKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKlnesnvqlenktscLKETQDQLLESQKKEKQLQE 1227
Cdd:PRK11637   45 NRDQLKSIQQDIAAKEKSVRQQQQQRASLLAQLKKQEEAISQASRK--------------LRETQNTLNQLNKQIDELNA 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1228 EAAKLsgELQQVQeangdikdslvkveelvkvlEEKLQAAtsQLDA--QQATNKELQELLvksqENEGNLQGESL----- 1300
Cdd:PRK11637  111 SIAKL--EQQQAA--------------------QERLLAA--QLDAafRQGEHTGLQLIL----SGEESQRGERIlayfg 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1301 ----AVTEKLQQLEQANGELKEalcQKenglKELQGKLDESNTVLESQKKShneiQDKLEQAQQ-KERTLQEETSKLAE- 1374
Cdd:PRK11637  163 ylnqARQETIAELKQTREELAA---QK----AELEEKQSQQKTLLYEQQAQ----QQKLEQARNeRKKTLTGLESSLQKd 231

                         250
                  ....*....|..
gi 442628159 1375 --QLSQLKQaNE 1384
Cdd:PRK11637  232 qqQLSELRA-NE 242
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1096-1318 1.57e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 43.28  E-value: 1.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1096 SERLIEKVtgiKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQElqdsvkQKEELVQN 1175
Cdd:PRK00409  500 PENIIEEA---KKLIGEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQE------EEDKLLEE 570

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1176 LEEKVREsssIIEAqntklnesnvqlenktscLKETQDQLLesqkKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEE 1255
Cdd:PRK00409  571 AEKEAQQ---AIKE------------------AKKEADEII----KELRQLQKGGYASVKAHELIEARKRLNKANEKKEK 625

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 442628159 1256 LVKVleeklqaatsqldaQQATNKELQ--------------ELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKE 1318
Cdd:PRK00409  626 KKKK--------------QKEKQEELKvgdevkylslgqkgEVLSIPDDKEAIVQAGIMKMKVPLSDLEKIQKPKKK 688
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 977-1171 1.65e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.89  E-value: 1.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  977 AEGERKEKSFEESIKNLQEEVTKAKTENLELstgtQTTIKDLQERLEITNAELQHKEKmasEDAQKIADLKTLVEAIQVA 1056
Cdd:COG3883    26 SELQAELEAAQAELDALQAELEELNEEYNEL----QAELEALQAEIDKLQAEIAEAEA---EIEERREELGERARALYRS 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1057 NANISATNAelstvleVLQAEK-SETNHIFELFEMEADMNSErLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQ 1135
Cdd:COG3883    99 GGSVSYLDV-------LLGSESfSDFLDRLSALSKIADADAD-LLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 442628159 1136 QSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEE 1171
Cdd:COG3883   171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELA 206
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 1132-1388 1.70e-03

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 42.49  E-value: 1.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1132 KQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEA---QNTKLNESNVQLENKTSCL 1208
Cdd:pfam15905   55 KVKSLELKKKSQKNLKESKDQKELEKEIRALVQERGEQDKRLQALEEELEKVEAKLNAavrEKTSLSASVASLEKQLLEL 134

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1209 KETQDqLLESQKKEKQLQEEAAKLSGELQQVQ-EANGDIKDSLVKVEELvkvlEEKLQAATSQLDAQQATNKELQELLVK 1287
Cdd:pfam15905  135 TRVNE-LLKAKFSEDGTQKKMSSLSMELMKLRnKLEAKMKEVMAKQEGM----EGKLQVTQKNLEHSKGKVAQLEEKLVS 209

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1288 S--QENEGNLQGESL--------AVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHN-------- 1349
Cdd:pfam15905  210 TekEKIEEKSETEKLleyitelsCVSEQVEKYKLDIAQLEELLKEKNDEIESLKQSLEEKEQELSKQIKDLNekcklles 289

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 442628159  1350 EIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQK 1388
Cdd:pfam15905  290 EKEELLREYEEKEQTLNAELEELKEKLTLEEQEHQKLQQ 328
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 564-944 1.73e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 43.08  E-value: 1.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  564 IRELNQQLDEVTTQLNVqkadsSALDDMLRLQKEGTEEKSTLLEKTEKELvqSKEQAAKTLNDKEQLEKQISDL-KQLAE 642
Cdd:NF033838   71 LSEIQKSLDKRKHTQNV-----ALNKKLSDIKTEYLYELNVLKEKSEAEL--TSKTKKELDAAFEQFKKDTLEPgKKVAE 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  643 QEKLVREMTENAINQIQlEKESIEQQLALKQNELE--DFQKKQSESEVHLQEIKAQNTQKDfelvesgESLKKLQQQLEQ 720
Cdd:NF033838  144 ATKKVEEAEKKAKDQKE-EDRRNYPTNTYKTLELEiaESDVEVKKAELELVKEEAKEPRDE-------EKIKQAKAKVES 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  721 KtlgheklQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLK 800
Cdd:NF033838  216 K-------KAEATRLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKRGVLGEPATPDKKENDAKSSDS 288

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  801 SQAEET--QSELKSTQSNLEAKSKQLEAangslEEEAKksghlleqitKLKSEVGETQAALSSCHTDVESKTKQLEAANA 878
Cdd:NF033838  289 SVGEETlpSPSLKPEKKVAEAEKKVEEA-----KKKAK----------DQKEEDRRNYPTNTYKTLELEIAESDVKVKEA 353

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 442628159  879 ALEKVNKEYAESRAEasdlqDKVKEItdtlhaelQAERSSSSALHTKLSKFSDEIATGHKELTSKA 944
Cdd:NF033838  354 ELELVKEEAKEPRNE-----EKIKQA--------KAKVESKKAEATRLEKIKTDRKKAEEEAKRKA 406
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1267-1452 1.96e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 1.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1267 ATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKK 1346
Cdd:COG3883    14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERAR 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1347 S----------------HNEIQDKLEQAQQKERtLQEETSKLAEQLSQLKQANEELQKSLQQKQlllekgNEFDTQLAEY 1410
Cdd:COG3883    94 AlyrsggsvsyldvllgSESFSDFLDRLSALSK-IADADADLLEELKADKAELEAKKAELEAKL------AELEALKAEL 166

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 442628159 1411 QKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTA 1452
Cdd:COG3883   167 EAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAA 208
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 1114-1217 2.00e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 42.76  E-value: 2.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1114 HLQLDERQKKFEELEEKLKQAQQSEQKLQQESQT-SKEKLTEIQQSLQELQ---DSVKQKEELVQNLEEKVRESSSIIEA 1189
Cdd:COG0542   403 RMEIDSKPEELDELERRLEQLEIEKEALKKEQDEaSFERLAELRDELAELEeelEALKARWEAEKELIEEIQELKEELEQ 482

                          90       100
                  ....*....|....*....|....*...
gi 442628159 1190 QNTKLNESNVQLENKTSCLKETQDQLLE 1217
Cdd:COG0542   483 RYGKIPELEKELAELEEELAELAPLLRE 510
PRK01156 PRK01156
chromosome segregation protein; Provisional
 513-1191 2.08e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 42.97  E-value: 2.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  513 RKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDeceiLQTEVRMRDEQIRELNQQLDEvttqlnvqkaDSSALDDML 592
Cdd:PRK01156  152 KKILDEILEINSLERNYDKLKDVIDMLRAEISNIDY----LEEKLKSSNLELENIKKQIAD----------DEKSHSITL 217

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  593 RLQKEGTEEkstlLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQlAEQEKLVREMTENAINQIQLEKESIEQQLAL- 671
Cdd:PRK01156  218 KEIERLSIE----YNNAMDDYNNLKSALNELSSLEDMKNRYESEIKT-AESDLSMELEKNNYYKELEERHMKIINDPVYk 292

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  672 KQNELEDFQKKQSESEVHLQEIKaqntQKDFELVESGESLKKLQQQleqktlghEKLQAALEELKKEKETIikekEQELQ 751
Cdd:PRK01156  293 NRNYINDYFKYKNDIENKKQILS----NIDAEINKYHAIIKKLSVL--------QKDYNDYIKKKSRYDDL----NNQIL 356

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  752 QLQSKSAESESALKVVQVQLEQLqqqaaasgEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSL 831
Cdd:PRK01156  357 ELEGYEMDYNSYLKSIESLKKKI--------EEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSL 428

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  832 EEEAKKSGHLLEQITKlKSEVGETQAALSSCHTDV--ESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEitdtlh 909
Cdd:PRK01156  429 NQRIRALRENLDELSR-NMEMLNGQSVCPVCGTTLgeEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVD------ 501

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  910 aelqaerssssalhtkLSKFSDEIATGHKEltskadawsqEMLQKEKELQELRQQLQDSQDSQTKLKaEGERKEKSFEES 989
Cdd:PRK01156  502 ----------------LKKRKEYLESEEIN----------KSINEYNKIESARADLEDIKIKINELK-DKHDKYEEIKNR 554

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  990 IKNLQEEVTKAKTE--NLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEaiqvananisatnael 1067
Cdd:PRK01156  555 YKSLKLEDLDSKRTswLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYID---------------- 618

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1068 STVLEVLQAEKSETNHIFELFEMEadmnseRLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQT 1147
Cdd:PRK01156  619 KSIREIENEANNLNNKYNEIQENK------ILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDD 692

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....
gi 442628159 1148 SKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQN 1191
Cdd:PRK01156  693 AKANRARLESTIEILRTRINELSDRINDINETLESMKKIKKAIG 736
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
1091-1318 2.12e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 42.21  E-value: 2.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1091 EADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKE 1170
Cdd:COG1340    19 ELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNEKLNELREELDELR 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1171 ELVQNLEEKVRESSSI---IEAQNTKLNESNVQLENKTSCLKETQD--QLLESQKKEKQLQEEAAKLSGELQQVQEANGD 1245
Cdd:COG1340    99 KELAELNKAGGSIDKLrkeIERLEWRQQTEVLSPEEEKELVEKIKEleKELEKAKKALEKNEKLKELRAELKELRKEAEE 178

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442628159 1246 IKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKE 1318
Cdd:COG1340   179 IHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEIVEAQEKADELHEEIIELQKELRELRKELKKLRK 251
mukB PRK04863
chromosome partition protein MukB;
802-1452 2.30e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 2.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  802 QAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAAL------SSCHTDVESKTKQLEA 875
Cdd:PRK04863  287 EALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALrqqekiERYQADLEELEERLEE 366

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  876 ANAALEKVNKEYAESRAEASDLQDKVKEITDTL-----------------HAELQAERSSSSALHtkLSKFSDEIATG-H 937
Cdd:PRK04863  367 QNEVVEEADEQQEENEARAEAAEEEVDELKSQLadyqqaldvqqtraiqyQQAVQALERAKQLCG--LPDLTADNAEDwL 444

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  938 KELTSKADAWSQEMLQKEKEL---QELRQQLQDSQDSQTKLKAEGERKE--KSFEESIKNLQEEvtKAKTENLElstGTQ 1012
Cdd:PRK04863  445 EEFQAKEQEATEELLSLEQKLsvaQAAHSQFEQAYQLVRKIAGEVSRSEawDVARELLRRLREQ--RHLAEQLQ---QLR 519

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1013 TTIKDLQERLEitnaelQHKekmaseDAQKIADlktlvEAIQVANANIsaTNAELstvLEVLQAEKSETnhifelfemea 1092
Cdd:PRK04863  520 MRLSELEQRLR------QQQ------RAERLLA-----EFCKRLGKNL--DDEDE---LEQLQEELEAR----------- 566

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1093 dmnserliekvtgiKEELKETHLQLDERQkkfEELEEKLKQAQQSEQKLQQES---QTSKEKLTEIQQSLQELQDSVKQK 1169
Cdd:PRK04863  567 --------------LESLSESVSEARERR---MALRQQLEQLQARIQRLAARApawLAAQDALARLREQSGEEFEDSQDV 629

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1170 EELVQNLEEKVREsssiieaqntkLNESNVQLENKTSCLKETQDQLLESQKKE-KQLQEEAAKLSGELQ-------QVQE 1241
Cdd:PRK04863  630 TEYMQQLLERERE-----------LTVERDELAARKQALDEEIERLSQPGGSEdPRLNALAERFGGVLLseiyddvSLED 698

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1242 A---------------------------------------NGDI---KDSLVKVEELVKVLEEKL--------------- 1264
Cdd:PRK04863  699 ApyfsalygparhaivvpdlsdaaeqlagledcpedlyliEGDPdsfDDSVFSVEELEKAVVVKIadrqwrysrfpevpl 778

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1265 ---QAATSQLDAQQATNKELQELLVKSQENEGNLQ----------GESLAV--------------------TEKLQQLEQ 1311
Cdd:PRK04863  779 fgrAAREKRIEQLRAEREELAERYATLSFDVQKLQrlhqafsrfiGSHLAVafeadpeaelrqlnrrrvelERALADHES 858

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1312 ANGELKEALCQKENGLKELQGKLDESNTVL-ESQKKSHNEIQDKLEQAQQKERTLQEETSKLA-------------EQLS 1377
Cdd:PRK04863  859 QEQQQRSQLEQAKEGLSALNRLLPRLNLLAdETLADRVEEIREQLDEAEEAKRFVQQHGNALAqlepivsvlqsdpEQFE 938

                         730       740       750       760       770       780       790
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442628159 1378 QLKQA---NEELQKSLQQKQLLLEKGNEFDTQLAeYQKVIDEMDDAasvkSALLEQLQNRVAELETALRQANDAQKTA 1452
Cdd:PRK04863  939 QLKQDyqqAQQTQRDAKQQAFALTEVVQRRAHFS-YEDAAEMLAKN----SDLNEKLRQRLEQAEQERTRAREQLRQA 1011
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 557-761 2.67e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.22  E-value: 2.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  557 VRMRDEQIRELNQQLDEVTTQLnvQKADSSALDDMLR-LQKEGTEEKSTLLEKTEKELVQ-----SKEQAAKTLN---DK 627
Cdd:PRK05771    4 VRMKKVLIVTLKSYKDEVLEAL--HELGVVHIEDLKEeLSNERLRKLRSLLTKLSEALDKlrsylPKLNPLREEKkkvSV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  628 EQLEKQISDLKQLAEQ-EKLVREMTENaINQIQLEKESIEQQLA--------------LKQNEL----------EDFQKK 682
Cdd:PRK05771   82 KSLEELIKDVEEELEKiEKEIKELEEE-ISELENEIKELEQEIErlepwgnfdldlslLLGFKYvsvfvgtvpeDKLEEL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  683 QSESEVHLQEIKAQNTQKDFELV--------ESGESLKKLQQQlEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQ 754
Cdd:PRK05771  161 KLESDVENVEYISTDKGYVYVVVvvlkelsdEVEEELKKLGFE-RLELEEEGTPSELIREIKEELEEIEKERESLLEELK 239


                  ....*..
gi 442628159  755 SKSAESE 761
Cdd:PRK05771  240 ELAKKYL 246
ClyA-like cd21116
family of the cytolysin A (ClyA) family alpha pore-forming toxins (alpha-PFT) including ...
 1130-1278 2.96e-03

family of the cytolysin A (ClyA) family alpha pore-forming toxins (alpha-PFT) including Bacillus cereus HblB, Aeromonas hydrophila AhlB, Bacillus thuringiensis Cry6Aa and similar proteins; This family belongs to the ClyA family of alpha-PFT bacterial toxins. PFTs form the major group of virulence factors in many pathogenic bacteria and in general are critical components of the molecular offensive and defensive machinery of cells in all kingdoms of life. Bacterial PFTs facilitate the takeover of host resources by puncturing holes in the membrane. PFTs can be classified as alpha-PFTs and beta-PFTs depending on the secondary structures of their membrane component. Alpha-PFTs use a ring of amphipathic helices while beta-PFTs use a beta-barrel to construct the pore. Members of this family include the toxins: Bacillus cereus hemolysin binding component B (HblB or HBL-B) of the diarrheal enterotoxin hemolysin BL, Aeromonas hydrophila hemolytic (Ahl) component B (AhlB) of the tripartite AhlABC toxin, Vibrio cholerae cytotoxin motility associated killing factor A (MakA) cytotoxin, Xenorhabdus nematophila alpha-xenorhabdolysin (XaxA), Bacillus thuringiensis crystal 6Aa (Cry6Aa) parasporal crystal (Cry) toxin, and Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA) of the non-hemolytic enterotoxin Nhe, which, despite its name, is hemolytic, among others. In solution, ClyA proteins have an elongated, almost entirely alpha-helical structure, except for a short hydrophobic beta-hairpin known as the beta-tongue. Pore formation by ClyA requires circular oligomerization of the toxin by a sequential mechanism. This, in turn, concentrates the amphipathic helices in the center of the ring-like structure, forming a helical barrel that inserts into the membrane by a wedge-like mechanism. Compared with ClyA, NheA is almost entirely alpha-helical with an enlarged "head" domain, and an enlarged beta-tongue; it has been proposed that NheA could even form beta-barrel pores. Alpha-PFTs with similar structures are increasingly being found in eukaryotes, in particular as components of the immune systems of animals. This family may be distantly related to Escherichia coli alpha-PFT hemolysin E (HlyE, also known as ClyA or SheA).


Pssm-ID: 439149 [Multi-domain]  Cd Length: 224  Bit Score: 40.86  E-value: 2.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1130 KLKQAQQSEQKLQQESQTSKEKLteiQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLK 1209
Cdd:cd21116    74 YYPDLIELADNLIKGDQGAKQQL---LQGLEALQSQVTKKQTSVTSFINELTTFKNDLDDDSRNLQTDATKAQAQVAVLN 150

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 442628159 1210 ETQDQLlesqkkeKQLQEEAAKLSGELQQVQEANGDIKDSLvkveelvKVLEEKLQAATSQLDAQQATN 1278
Cdd:cd21116   151 ALKNQL-------NSLAEQIDAAIDALEKLSNDWQTLDSDI-------KELITDLEDAESSIDAAFLQA 205
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 342-670 2.99e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.22  E-value: 2.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  342 KARIVelesALDNERKKT-EELQcSIDEAQFCgdELNAQSQVykEKIHDLESKITKLVSATPSLQSILPPDlpsddGALQ 420
Cdd:PRK05771    8 KVLIV----TLKSYKDEVlEALH-ELGVVHIE--DLKEELSN--ERLRKLRSLLTKLSEALDKLRSYLPKL-----NPLR 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  421 EEIAKLQEKMTIQQKEVESRIAEQLEEEqrlrenVKYLNEQIATLQSELvskdEALEKfslsecgienlrrelellkeen 500
Cdd:PRK05771   74 EEKKKVSVKSLEELIKDVEEELEKIEKE------IKELEEEISELENEI----KELEQ---------------------- 121

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  501 ekqaqeaqaeftrklAEKSVEVLR-LSSELQNLKATSD-SLESERVNKTDECEILQTEVrmrDEQIRELNQQLDEVTTQL 578
Cdd:PRK05771  122 ---------------EIERLEPWGnFDLDLSLLLGFKYvSVFVGTVPEDKLEELKLESD---VENVEYISTDKGYVYVVV 183

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  579 NVQKADSSALDDMLRlqKEGTEEKSTLLEKTEKELVQSKEQAAKTLND-KEQLEKQISDLKQLAEQEKLVREmtenAINQ 657
Cdd:PRK05771  184 VVLKELSDEVEEELK--KLGFERLELEEEGTPSELIREIKEELEEIEKeRESLLEELKELAKKYLEELLALY----EYLE 257

                         330
                  ....*....|...
gi 442628159  658 IQLEKESIEQQLA 670
Cdd:PRK05771  258 IELERAEALSKFL 270
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 598-755 3.57e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 41.94  E-value: 3.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   598 GTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQeklvremTENAINQIQLEKESIEQQLALK----- 672
Cdd:pfam05667  322 KVETEEELQQQREEELEELQEQLEDLESSIQELEKEIKKLESSIKQ-------VEEELEELKEQNEELEKQYKVKkktld 394

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   673 -----QNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKL--------QQQLEQKTLGHEKLQAALEELKKek 739
Cdd:pfam05667  395 llpdaEENIAKLQALVDASAQRLVELAGQWEKHRVPLIEEYRALKEAksnkedesQRKLEEIKELREKIKEVAEEAKQ-- 472

                          170
                   ....*....|....*.
gi 442628159   740 etiikeKEQELQQLQS 755
Cdd:pfam05667  473 ------KEELYKQLVA 482
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 979-1370 3.72e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 41.87  E-value: 3.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  979 GERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANA 1058
Cdd:COG5185   177 KKLEIFGLTLGLLKGISELKKAEPSGTVNSIKESETGNLGSESTLLEKAKEIINIEEALKGFQDPESELEDLAQTSDKLE 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1059 NISATNAELSTVLEVLQAEKSE-----TNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQldeRQKKFEELEEKLKQ 1133
Cdd:COG5185   257 KLVEQNTDLRLEKLGENAESSKrlnenANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLA---AAEAEQELEESKRE 333

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1134 AQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNlEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKET-Q 1212
Cdd:COG5185   334 TETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVELSKS-SEELDSFKDTIESTKESLDEIPQNQRGYAQEILATlE 412

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1213 DQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLeeklqaatSQLDAQQATNKELQELLVKSQENE 1292
Cdd:COG5185   413 DTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEE--------SQSRLEEAYDEINRSVRSKKEDLN 484

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1293 GNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTV--LESQKKSHNEIQDKLEQAQQKERTLQEETS 1370
Cdd:COG5185   485 EELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRArgYAHILALENLIPASELIQASNAKTDGQAAN 564
COG4487 COG4487
Uncharacterized conserved protein, contains DUF2130 domain [Function unknown];
601-761 3.75e-03

Uncharacterized conserved protein, contains DUF2130 domain [Function unknown];


Pssm-ID: 443580 [Multi-domain]  Cd Length: 425  Bit Score: 41.47  E-value: 3.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  601 EKSTLLEKTEKELVQSKEQAAKTLNDK-EQLEKQISDLKQ-----LAEQEKLVREMTENAINQIQLEKESIEQQLALKQN 674
Cdd:COG4487    37 ERLADAAKREAALELAEAKAKAQLQEQvAEKDAEIAELRArleaeERKKALAVAEEKEKELAALQEALAEKDAKLAELQA 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  675 ELEDFQKKQSESEVHLQEIKAQnTQKdfELVESGESLK-KLQQQLEQKTLGHEKLQAA-----LEELKKEKETIIKEKEQ 748
Cdd:COG4487   117 KELELLKKERELEDAKREAELT-VEK--ERDEELDELKeKLKKEEEEKQLAEKSLKVAeyekqLKDMQEQIEELKRKKEQ 193

                         170
                  ....*....|...
gi 442628159  749 ELQQLQSKSAESE 761
Cdd:COG4487   194 GSTQLQGEVLELE 206
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1012-1242 3.84e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 3.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1012 QTTIKDLQERLEITNA------ELqhkeKMASEDAQKIAD-LKTLVEA-----IQVANANISATNAELSTVLEVLQAEKS 1079
Cdd:COG3206   117 EAAIERLRKNLTVEPVkgsnviEI----SYTSPDPELAAAvANALAEAyleqnLELRREEARKALEFLEEQLPELRKELE 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1080 ETNHIFELFE-----MEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLK--------------------QA 1134
Cdd:COG3206   193 EAEAALEEFRqknglVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGsgpdalpellqspviqqlraQL 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1135 QQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQ 1214
Cdd:COG3206   273 AELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAE 352

                         250       260
                  ....*....|....*....|....*...
gi 442628159 1215 LLESQKKEKQLQEEAAKLSGELQQVQEA 1242
Cdd:COG3206   353 LRRLEREVEVARELYESLLQRLEEARLA 380
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 302-1001 4.72e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 41.88  E-value: 4.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   302 MQDLLREKQQHVEKLMVERDldredAQNQALQLQKNINELKARIVEL---ESALDNERKKTEeLQCSIDEAQFCGDELNA 378
Cdd:TIGR00618  231 LREALQQTQQSHAYLTQKRE-----AQEEQLKKQQLLKQLRARIEELraqEAVLEETQERIN-RARKAAPLAAHIKAVTQ 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   379 QSQVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDGALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYL 458
Cdd:TIGR00618  305 IEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTL 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   459 NEQIATLQSELVSKDEALEKFSlsecgiENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQnlkatsds 538
Cdd:TIGR00618  385 QQQKTTLTQKLQSLCKELDILQ------REQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCT-------- 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   539 leservnktdeceilQTEVRMRDEQIRELNQQLDEvttqlnvqkadssalddmlRLQKEGTEEKSTLLEKTEKELVQSKE 618
Cdd:TIGR00618  451 ---------------AQCEKLEKIHLQESAQSLKE-------------------REQQLQTKEQIHLQETRKKAVVLARL 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   619 QaaktlndkEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKesIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNT 698
Cdd:TIGR00618  497 L--------ELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQR--GEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQ 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   699 QKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQA 778
Cdd:TIGR00618  567 EIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLT 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   779 AASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAA 858
Cdd:TIGR00618  647 ALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENA 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   859 LSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHK 938
Cdd:TIGR00618  727 SSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEA 806

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442628159   939 ELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAK 1001
Cdd:TIGR00618  807 EIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQA 869
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
605-859 5.31e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.04  E-value: 5.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  605 LLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQS 684
Cdd:COG4372    18 LRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  685 ESEVHLQEIKAQNTQKDFELvesgESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAL 764
Cdd:COG4372    98 QAQEELESLQEEAEELQEEL----EELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQEL 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  765 KVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQ 844
Cdd:COG4372   174 QALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLE 253

                         250
                  ....*....|....*
gi 442628159  845 ITKLKSEVGETQAAL 859
Cdd:COG4372   254 EVILKEIEELELAIL 268
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1154-1381 5.75e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 40.77  E-value: 5.75e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   1154 EIQQ-SLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQlLESQK-----KEKQLQE 1227
Cdd:smart00787   66 ELYQfSCKELKKYISEGRDLFKEIEEETLINNPPLFKEYFSASPDVKLLMDKQFQLVKTFAR-LEAKKmwyewRMKLLEG 144

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   1228 EAAKLSGELQQVQEAngdiKDSLVKVEELVKVLEEKLQaatsqlDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQ 1307
Cdd:smart00787  145 LKEGLDENLEGLKED----YKLLMKELELLNSIKPKLR------DRKDALEEELRQLKQLEDELEDCDPTELDRAKEKLK 214

                           170       180       190       200       210       220       230
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 442628159   1308 QLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTlqeETSKLAEQLSQLKQ 1381
Cdd:smart00787  215 KLLQEIMIKVKKLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQCRGFTFK---EIEKLKEQLKLLQS 285
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1223-1531 6.23e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.48  E-value: 6.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1223 KQLQEEAAKLSGELQQVQEANGDIKDSLVkveELVKVLEEkLQAATSQLDAQ-QATNKELqellvksqenegNLQGESLA 1301
Cdd:COG3096   281 RELSERALELRRELFGARRQLAEEQYRLV---EMARELEE-LSARESDLEQDyQAASDHL------------NLVQTALR 344

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1302 VTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEEtsklAEQLSQLKQ 1381
Cdd:COG3096   345 QQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTR----AIQYQQAVQ 420

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1382 ANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE-----------MDDAASVKSALLEQLQNRVAELETA--------- 1441
Cdd:COG3096   421 ALEKARALCGLPDLTPENAEDYLAAFRAKEQQATEevleleqklsvADAARRQFEKAYELVCKIAGEVERSqawqtarel 500

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1442 LRQANDAQKTAYLETkELRRQLESLE--LEKSREVLSLKAQMNGASSRS-GKGDEVESL------DIETSLAKINFLNSI 1512
Cdd:COG3096   501 LRRYRSQQALAQRLQ-QLRAQLAELEqrLRQQQNAERLLEEFCQRIGQQlDAAEELEELlaeleaQLEELEEQAAEAVEQ 579

                         330
                  ....*....|....*....
gi 442628159 1513 IADMQQKNDALKAKVQTLE 1531
Cdd:COG3096   580 RSELRQQLEQLRARIKELA 598
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
513-754 6.50e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 6.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  513 RKLAEKSVEVLRL--------SSELQNLKATSDSLESERVNKTDeceILQTEVRMRD-EQIRELNQQLDE--VTTQLNVQ 581
Cdd:COG3206    93 RPVLERVVDKLNLdedplgeeASREAAIERLRKNLTVEPVKGSN---VIEISYTSPDpELAAAVANALAEayLEQNLELR 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  582 KADSSALDDMLRLQKEGTEEKstlLEKTEKELV--QSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQI- 658
Cdd:COG3206   170 REEARKALEFLEEQLPELRKE---LEEAEAALEefRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALr 246

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  659 -QLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLG--------HEKLQ 729
Cdd:COG3206   247 aQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRilasleaeLEALQ 326

                         250       260       270
                  ....*....|....*....|....*....|.
gi 442628159  730 AALEELKKEKETI------IKEKEQELQQLQ 754
Cdd:COG3206   327 AREASLQAQLAQLearlaeLPELEAELRRLE 357
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1045-1190 6.61e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 40.39  E-value: 6.61e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   1045 DLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNH-IFELFEMEADMNSERLIEkVTGIKEELKETHLQLDERQKK 1123
Cdd:smart00787  148 GLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEeLRQLKQLEDELEDCDPTE-LDRAKEKLKKLLQEIMIKVKK 226

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 442628159   1124 FEELEEKLkqaqqseQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQ 1190
Cdd:smart00787  227 LEELEEEL-------QELESKIEDLTNKKSELNTEIAEAEKKLEQCRGFTFKEIEKLKEQLKLLQSL 286
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1305-1452 6.82e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.91  E-value: 6.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1305 KLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQE--ETSKLAEQLSQLKQA 1382
Cdd:COG1579    18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEqlGNVRNNKEYEALQKE 97

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 442628159 1383 NEELQKSLQQ-KQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTA 1452
Cdd:COG1579    98 IESLKRRISDlEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1280-1394 7.14e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 40.97  E-value: 7.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1280 ELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDES-NTVLESQKKSHNEIQDKLEQA 1358
Cdd:PRK00409  517 KLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEaQQAIKEAKKEADEIIKELRQL 596

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 442628159 1359 QQKERTLQEEtSKLAEQLSQLKQANEELQKSLQQKQ 1394
Cdd:PRK00409  597 QKGGYASVKA-HELIEARKRLNKANEKKEKKKKKQK 631
PRK01156 PRK01156
chromosome segregation protein; Provisional
 899-1399 7.45e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 41.04  E-value: 7.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  899 DKVKEITDTLhaelQAERSSSSALHTKLSKFSDEIATGHKELTSkaDAWSQEMLQKEKElqELRQQLQDSQDSQTKLKAE 978
Cdd:PRK01156  169 DKLKDVIDML----RAEISNIDYLEEKLKSSNLELENIKKQIAD--DEKSHSITLKEIE--RLSIEYNNAMDDYNNLKSA 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  979 GERKeKSFEESIKNLQEEVTKAKTEnLELSTGTQTTIKDLQERL-EITNAELQHKEKMASEDAQKIADLKTLVEAIQVAN 1057
Cdd:PRK01156  241 LNEL-SSLEDMKNRYESEIKTAESD-LSMELEKNNYYKELEERHmKIINDPVYKNRNYINDYFKYKNDIENKKQILSNID 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1058 ANISATNAELSTvLEVLQAEKSE-----------TNHIFELFEMEADMNS-----ERLIEKV-----------TGIKEEL 1110
Cdd:PRK01156  319 AEINKYHAIIKK-LSVLQKDYNDyikkksryddlNNQILELEGYEMDYNSylksiESLKKKIeeyskniermsAFISEIL 397

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1111 KETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQEL------------------QDSVKQKEEL 1172
Cdd:PRK01156  398 KIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLngqsvcpvcgttlgeeksNHIINHYNEK 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1173 VQNLEEKVREsssiIEAQNTKLNESNVQLENKTSCLK-------ETQDQLLESQKKE-KQLQEEAAKLSGELQQVQEANG 1244
Cdd:PRK01156  478 KSRLEEKIRE----IEIEVKDIDEKIVDLKKRKEYLEseeinksINEYNKIESARADlEDIKIKINELKDKHDKYEEIKN 553

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1245 DIKDslVKVEELVKVLEE--KLQAATSQLDAQ------QATNKELQELLVKSQENEGNLQGESLAVTEKLQQLE------ 1310
Cdd:PRK01156  554 RYKS--LKLEDLDSKRTSwlNALAVISLIDIEtnrsrsNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIEneannl 631

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1311 -------QANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQAN 1383
Cdd:PRK01156  632 nnkyneiQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRI 711

                         570
                  ....*....|....*.
gi 442628159 1384 EELQKSLQQKQLLLEK 1399
Cdd:PRK01156  712 NELSDRINDINETLES 727
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 1101-1348 7.85e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 41.19  E-value: 7.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1101 EKVTGIKEELKETHLQLDERQKK------FEELEEKLKQAQQSEQKLQQESQTSkEKLTEIQQSLQELQDSVKQKEELVQ 1174
Cdd:PTZ00108 1102 EKVEKLNAELEKKEKELEKLKNTtpkdmwLEDLDKFEEALEEQEEVEEKEIAKE-QRLKSKTKGKASKLRKPKLKKKEKK 1180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1175 NLEEKVRESSSIIEAQNTKLNESNVQLE-----NKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDS 1249
Cdd:PTZ00108 1181 KKKSSADKSKKASVVGNSKRVDSDEKRKlddkpDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNDEF 1260

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1250 LVKVEELVKVLEEKLQAATSQLDAQQATNKEL-QELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLK 1328
Cdd:PTZ00108 1261 SSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPdGESNGGSKPSSPTKKKVKKRLEGSLAALKKKKKSEKKTARKKKSKTR 1340

                         250       260
                  ....*....|....*....|
gi 442628159 1329 ELQGKlDESNTVLESQKKSH 1348
Cdd:PTZ00108 1341 VKQAS-ASQSSRLLRRPRKK 1359
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 854-1471 7.92e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 41.19  E-value: 7.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   854 ETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITD------TLHAELQAERSSSSALHTKLS 927
Cdd:TIGR01612  541 EIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDeiiyinKLKLELKEKIKNISDKNEYIK 620

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159   928 KfsdeiATGHKELTSKADAWSQEmLQKEKELQELRQQLQDSQDSQTkLKAEgerKEKSFEESIKNLQEEVTKAKTENLEL 1007
Cdd:TIGR01612  621 K-----AIDLKKIIENNNAYIDE-LAKISPYQVPEHLKNKDKIYST-IKSE---LSKIYEDDIDALYNELSSIVKENAID 690

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1008 STGTQTTIKDLQERLEITNAELQHKEKMASE------DAQKIADLKTLVEAIQVANANIsatNAELSTVLEVLQA-EKSE 1080
Cdd:TIGR01612  691 NTEDKAKLDDLKSKIDKEYDKIQNMETATVElhlsniENKKNELLDIIVEIKKHIHGEI---NKDLNKILEDFKNkEKEL 767

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1081 TNHIFELFEMEADMNSERliEKVTGIK--------------EELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQE-- 1144
Cdd:TIGR01612  768 SNKINDYAKEKDELNKYK--SKISEIKnhyndqinidnikdEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDfl 845

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1145 ---------SQTSKEKLTEIQQSLQELQDSVKQK--EELVQNLEEKVRESSSIIEAQNTKLNE--SNVQLENKTS----C 1207
Cdd:TIGR01612  846 nkvdkfinfENNCKEKIDSEHEQFAELTNKIKAEisDDKLNDYEKKFNDSKSLINEINKSIEEeyQNINTLKKVDeyikI 925

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1208 LKETQDQLLESQKKEKQLQEeaaKLSGELQQVQEAN-------GDIKDSLV-KVEELVKVLEEklqaatSQLDAQQATNK 1279
Cdd:TIGR01612  926 CENTKESIEKFHNKQNILKE---ILNKNIDTIKESNlieksykDKFDNTLIdKINELDKAFKD------ASLNDYEAKNN 996

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1280 ELQELLVKSQENEGNLQGESL---------AVTEKLQQLEQANGELKE-------ALCQKENGLKELQGKLDES--NTVL 1341
Cdd:TIGR01612  997 ELIKYFNDLKANLGKNKENMLyhqfdekekATNDIEQKIEDANKNIPNieiaihtSIYNIIDEIEKEIGKNIELlnKEIL 1076

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1342 ESQKKS---HNEIQDKLEQAQQKErTLQEETSKLAEQLSQLKQ----ANEELQKSLQQKQLLLEKG----NEFDTQLAEY 1410
Cdd:TIGR01612 1077 EEAEINitnFNEIKEKLKHYNFDD-FGKEENIKYADEINKIKDdiknLDQKIDHHIKALEEIKKKSenyiDEIKAQINDL 1155

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 442628159  1411 QKVIDEMDDAASVKSaLLEQLQNRVAELetalrqanDAQKTAYLETKELRRQLESLELEKS 1471
Cdd:TIGR01612 1156 EDVADKAISNDDPEE-IEKKIENIVTKI--------DKKKNIYDEIKKLLNEIAEIEKDKT 1207
COG5391 COG5391
Phox homology (PX) domain protein [Intracellular trafficking and secretion / General function ...
 1083-1238 8.61e-03

Phox homology (PX) domain protein [Intracellular trafficking and secretion / General function prediction only];


Pssm-ID: 227680 [Multi-domain]  Cd Length: 524  Bit Score: 40.55  E-value: 8.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1083 HIFELFEMEAdMNSERLIEKVTGIKEELKETHLQ-LDERQ---KKFEELEEKLkqAQQSEQKLQQESQTSKEKLTEIQ-- 1156
Cdd:COG5391   301 SIFSLFEKIL-IQLESEEESLTRLLESLNNLLLLvLNFSGvfaKRLEQNQNSI--LNEGVVQAETLRSSLKELLTQLQde 377

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1157 -QSLQELQDSVKQKEELVQNLEEKVRESSSIiEAQNTKLNESNV-QLENKTSCLKETQ-----DQLLESQKKEKQLQEEA 1229
Cdd:COG5391   378 iKSRESLILTDSNLEKLTDQNLEDVEELSRS-LRKNSSQRAVVSqQPEGLTSFSKLSYklrdfVQEKSRSKSIESLQQDK 456


                  ....*....
gi 442628159 1230 AKLSGELQQ 1238
Cdd:COG5391   457 EKLEEQLAI 465
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
562-1163 9.11e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.67  E-value: 9.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  562 EQIRELNQQLDEVTTQLNVQKAdssaLDDMLRLQKEgtEEKSTLLEKtekELVQSKEQAAKTLNDKEQLEKQISDLKQLA 641
Cdd:COG4913   255 EPIRELAERYAAARERLAELEY----LRAALRLWFA--QRRLELLEA---ELEELRAELARLEAELERLEARLDALREEL 325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  642 EQeklvremTENAINQIQLE-KESIEQQLALKQNELEDFQKKQSESEVHLQEIkaqntqkDFELVESGESLKKLQQQLEQ 720
Cdd:COG4913   326 DE-------LEAQIRGNGGDrLEQLEREIERLERELEERERRRARLEALLAAL-------GLPLPASAEEFAALRAEAAA 391

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  721 KTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAlkvvqvqleqlqqqaaasgeeGSKTVAKLHDEISQLK 800
Cdd:COG4913   392 LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR---------------------KSNIPARLLALRDALA 450

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  801 SQAEETQSELK------------------------STQSNLEAKSKQLEAANGSLE----------EEAKKSGHLLEQIT 846
Cdd:COG4913   451 EALGLDEAELPfvgelievrpeeerwrgaiervlgGFALTLLVPPEHYAAALRWVNrlhlrgrlvyERVRTGLPDPERPR 530

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  847 --------KLKSEVGETQAALSS---------CHTDVE--------------------------------------SKTK 871
Cdd:COG4913   531 ldpdslagKLDFKPHPFRAWLEAelgrrfdyvCVDSPEelrrhpraitragqvkgngtrhekddrrrirsryvlgfDNRA 610

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  872 QLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSS-----ALHTKLSKFSDEIAtghkeltsKADA 946
Cdd:COG4913   611 KLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDeidvaSAEREIAELEAELE--------RLDA 682

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  947 WSQEMLQKEKELQELRQQLQDSQDSQTKLKaegeRKEKSFEESIKNLQEEVTKAKTENLEL-STGTQTTIKDLQERLEIT 1025
Cdd:COG4913   683 SSDDLAALEEQLEELEAELEELEEELDELK----GEIGRLEKELEQAEEELDELQDRLEAAeDLARLELRALLEERFAAA 758

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1026 NAELQHKEKMASedaqkiadlktLVEAIQVANANISATNAELSTVLEVLQAEksetnHIFELFEMEADMNSerlIEKVTG 1105
Cdd:COG4913   759 LGDAVERELREN-----------LEERIDALRARLNRAEEELERAMRAFNRE-----WPAETADLDADLES---LPEYLA 819

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159 1106 IKEELKETHLQldERQKKFEELEEKLKQAQQSE--QKLQQESQTSKEKLTEIQQSLQELQ 1163
Cdd:COG4913   820 LLDRLEEDGLP--EYEERFKELLNENSIEFVADllSKLRRAIREIKERIDPLNDSLKRIP 877
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
418-805 9.13e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.52  E-value: 9.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  418 ALQEEIAKLQEkmtiQQKEVESRIAEQLEEEQRLRENVKYLN--EQIATLQSELVSKDEALEKFSLSECGIENLRRELEl 495
Cdd:COG4717    92 ELQEELEELEE----ELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPERLEELEERLEELRELEEELE- 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  496 lkeENEKQAQEAQAEFTRKLAEKSVEVLRlssELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVT 575
Cdd:COG4717   167 ---ELEAELAELQEELEELLEQLSLATEE---ELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAA 240

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  576 TQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAA-----KTLNDKEQLEKQISDLKQLAEQEKLVREM 650
Cdd:COG4717   241 LEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLallflLLAREKASLGKEAEELQALPALEELEEEE 320

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  651 TENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDF-------------ELVESGESLKKLQQQ 717
Cdd:COG4717   321 LEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIaallaeagvedeeELRAALEQAEEYQEL 400

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  718 LEQKTLGHEKLQAALEELKKEKETIIKEK-EQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGskTVAKLHDEI 796
Cdd:COG4717   401 KEELEELEEQLEELLGELEELLEALDEEElEEELEELEEELEELEEELEELREELAELEAELEQLEEDG--ELAELLQEL 478


                  ....*....
gi 442628159  797 SQLKSQAEE 805
Cdd:COG4717   479 EELKAELRE 487
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1097-1500 9.47e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 40.58  E-value: 9.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1097 ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLK------QAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKE 1170
Cdd:pfam10174  126 ERQAKELFLLRKTLEEMELRIETQKQTLGARDESIKkllemlQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKE 205

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1171 -ELVQNLEEKVRESSSIIEAQNTKLNESNVQLenktsclKETQDQLLESQKKEKQLQEEAAKLSGELqqvqeaNGDIKDS 1249
Cdd:pfam10174  206 kENIHLREELHRRNQLQPDPAKTKALQTVIEM-------KDTKISSLERNIRDLEDEVQMLKTNGLL------HTEDREE 272

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1250 LVKVEELVKVLEEKLQAATSQLDaqQATNKELQELLVksqenegnLQGESLAVTEKLQQLEQANGELKEALCQKENGLKE 1329
Cdd:pfam10174  273 EIKQMEVYKSHSKFMKNKIDQLK--QELSKKESELLA--------LQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAAI 342

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1330 LQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQkqlLLEKGNEFDTQLAE 1409
Cdd:pfam10174  343 LQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIEN---LQEQLRDKDKQLAG 419

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628159  1410 YQKVIDE--------------MDDAASVKSALLEQLQNRVAELETALRQANDAQKTaylETKELRRQLESLE---LEKSR 1472
Cdd:pfam10174  420 LKERVKSlqtdssntdtalttLEEALSEKERIIERLKEQREREDRERLEELESLKK---ENKDLKEKVSALQpelTEKES 496

                          410       420
                   ....*....|....*....|....*....
gi 442628159  1473 EVLSLKAQMNGASSRSGKGD-EVESLDIE 1500
Cdd:pfam10174  497 SLIDLKEHASSLASSGLKKDsKLKSLEIA 525
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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