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Conserved domains on  [gi|28893573|ref|NP_796366|]
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transmembrane protein 220 isoform 1 [Mus musculus]

Protein Classification

transmembrane 220 family protein( domain architecture ID 10633391)

transmembrane 220 (TMEM220) family protein similar to human transmembrane protein 220, which is a DNA methylation marker in human gastric cancer

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TMEM220 pfam15071
Transmembrane family 220, helix; Transmembrane 220 (TMEM220) is a domain of unknown function. ...
 29-144 1.46e-24

Transmembrane family 220, helix; Transmembrane 220 (TMEM220) is a domain of unknown function. It is thought to be a transmembrane helix. The length of this protein is typically between 150 and 160 amino acids. In humans, it is found in the chromosomal position 17p13.1.


:

Pssm-ID: 434437  Cd Length: 100  Bit Score: 92.01  E-value: 1.46e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28893573    29 VVQVNDPDAELWVtrksfcreslyqrlplpmttpgmtVVYMIPAVLTLLVGFNPLVTGnfIWKSVSAIHMLFCAL----W 104
Cdd:pfam15071   7 YVQLNDPDPYLWV------------------------PIYLLPALLCLLAALGPAVTG--LWRALAVLYLLAAILfaldW 60

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 28893573   105 AGGLAYHFLLHAKQNLLNEEEGRELSGLVIVTAWMALCHS 144
Cdd:pfam15071  61 LAMLGGLLLTEMSAEILHIEEGREFFGLLIVALWMLLCRF 100
 
Name Accession Description Interval E-value
TMEM220 pfam15071
Transmembrane family 220, helix; Transmembrane 220 (TMEM220) is a domain of unknown function. ...
 29-144 1.46e-24

Transmembrane family 220, helix; Transmembrane 220 (TMEM220) is a domain of unknown function. It is thought to be a transmembrane helix. The length of this protein is typically between 150 and 160 amino acids. In humans, it is found in the chromosomal position 17p13.1.


Pssm-ID: 434437  Cd Length: 100  Bit Score: 92.01  E-value: 1.46e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28893573    29 VVQVNDPDAELWVtrksfcreslyqrlplpmttpgmtVVYMIPAVLTLLVGFNPLVTGnfIWKSVSAIHMLFCAL----W 104
Cdd:pfam15071   7 YVQLNDPDPYLWV------------------------PIYLLPALLCLLAALGPAVTG--LWRALAVLYLLAAILfaldW 60

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 28893573   105 AGGLAYHFLLHAKQNLLNEEEGRELSGLVIVTAWMALCHS 144
Cdd:pfam15071  61 LAMLGGLLLTEMSAEILHIEEGREFFGLLIVALWMLLCRF 100
 
Name Accession Description Interval E-value
TMEM220 pfam15071
Transmembrane family 220, helix; Transmembrane 220 (TMEM220) is a domain of unknown function. ...
 29-144 1.46e-24

Transmembrane family 220, helix; Transmembrane 220 (TMEM220) is a domain of unknown function. It is thought to be a transmembrane helix. The length of this protein is typically between 150 and 160 amino acids. In humans, it is found in the chromosomal position 17p13.1.


Pssm-ID: 434437  Cd Length: 100  Bit Score: 92.01  E-value: 1.46e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28893573    29 VVQVNDPDAELWVtrksfcreslyqrlplpmttpgmtVVYMIPAVLTLLVGFNPLVTGnfIWKSVSAIHMLFCAL----W 104
Cdd:pfam15071   7 YVQLNDPDPYLWV------------------------PIYLLPALLCLLAALGPAVTG--LWRALAVLYLLAAILfaldW 60

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 28893573   105 AGGLAYHFLLHAKQNLLNEEEGRELSGLVIVTAWMALCHS 144
Cdd:pfam15071  61 LAMLGGLLLTEMSAEILHIEEGREFFGLLIVALWMLLCRF 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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